Nitric oxide activation of peroxisome proliferator-activated receptor gamma through a p38 MAPK signaling pathway

FASEB Journal

Volumn 21, Issue 3, 2007, Pages 950-961

  Ptasinska, Anetta ^a   Wang, Shuibang ^a   Zhang, Jianhua ^a   Wesley, Robert A ^a   Danner, Robert L ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Endothelial cells; Gene expression; Inflammation; Peroxisome proliferator response element; Vascular homeostasis

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYCLOOXYGENASE 2; DIACYLGLYCEROL KINASE; DIACYLGLYCEROL KINASE ALPHA; DIETHYLENETRIAMINE; HEME OXYGENASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; N MONOMETHYL LEVO ARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; S NITROSOGLUTATHIONE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VIVO STUDY; PRIORITY JOURNAL; UMBILICAL VEIN;

CELLS, CULTURED; CYCLIC GMP; CYCLOOXYGENASE 2; DIACYLGLYCEROL KINASE; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; HUMANS; MEMBRANE PROTEINS; NITRIC OXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PPAR GAMMA; PROMOTER REGIONS (GENETICS); SIGNAL TRANSDUCTION;

EID: 33847413743     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.06-6822com     Document Type: Article

References (48)

1. Cines, D. B., Pollak, E. S., Buck, C. A., Loscalzo, J., Zimmerman, G. A., McEver, R. P., Pober, J. S., Wick, T. M., Konkle, B. A., Schwartz, B. S., et al. (1998) Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 91, 3527-3561
2. Forstermann, U., Schmidt, H. H., Pollock, J. S., Sheng, H., Mitchell, J. A., Warner, T. D., Nakane, M., and Murad, F. (1991) Isoforms of nitric oxide synthase. Characterization and purification from different cell types. Biochem. Pharmacol. 42, 1849-1857
3. Moncada, S., Palmer, R. M., and Higgs, E. A. (1991) Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43, 109-142
4. Cobb, J. P., and Danner, R. L. (1996) Nitric oxide and septic shock. JAMA 275, 1192-1196
5. Van Dervort, A. L., Yan, L., Madara, P. J., Cobb, J. P., Wesley, R. A., Corriveau, C. C., Tropea, M. M., and Danner, R. L. (1994) Nitric oxide regulates endotoxin-induced TNF-alpha production by human neutrophils. J. Immunol. 152, 4102-4109
6. Peng, H. B., Rajavashisth, T. B., Libby, P., and Liao, J. K. (1995) Nitric oxide inhibits macrophage-colony stimulating factor gene transcription in vascular endothelial cells. J. Biol. Chem. 270, 17050-17055
7. Cui, X., Zhang, J., Ma, P., Myers, D. E., Goldberg, I. G., Sittler, K. J., Barb, J. J., Munson, P. J., Cintron Adel, P., McCoy, J. P., et al. (2005) cGMP-independent nitric oxide signaling and regulation of the cell cycle. BMC Genomics 6, 151
8. Pilz, R. B., Suhasini, M., Idriss, S., Meinkoth, J. L., and Boss, G. R. (1995) Nitric oxide and cGMP analogs activate transcription from AP-1-responsive promoters in mammalian cells. FASEB J. 9, 552-558
9. Corriveau, C. C., Madara, P. J., Van Dervort, A. L., Tropea, M. M., Wesley, R. A., and Danner, R. L. (1998) Effects of nitric oxide on chemotaxis and endotoxin-induced interleukin-8 production in human neutrophils. J. Infect. Dis. 177, 116-126
10. Azuma, H., Ishikawa, M., and Sekizaki, S. (1986) Endotheliumdependent inhibition of platelet aggregation. Br. J. Pharmacol. 88, 411-415
11. Wever, R. M., Luscher, T. F., Cosentino, F., and Rabelink, T. J. (1998) Atherosclerosis and the two faces of endothelial nitric oxide synthase. Circulation 97, 108-112
12. Patel, R. P., Levonen, A., Crawford, J. H., and Darley-Usmar, V. M. (2000) Mechanisms of the pro- and anti-oxidant actions of nitric oxide in atherosclerosis. Cardiovasc. Res. 47, 465-474
13. Garthwaite, J., Charles, S. L., and Chess-Williams, R. (1988) Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature 336, 385-388
14. Knowles, R. G., Palacios, M., Palmer, R. M., and Moncada, S. (1989) Formation of nitric oxide from l-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase. Proc. Natl. Acad. Sci. U. S. A. 86, 5159-5162
15. Kubes, P., Kanwar, S., Niu, X. F., and Gaboury, J. P. (1993) Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells. FASEB J. 7, 1293-1299
16. Wang, S., Yan, L., Wesley, R. A., and Danner, R. L. (1997) Nitric oxide increases tumor necrosis factor production in differentiated U937 cells by decreasing cyclic AMP. J. Biol. Chem. 272, 5959-5965
17. Zhang, J., Wang, S., Wesley, R. A., and Danner, R. L. (2003) Adjacent sequence controls the response polarity of nitric oxide-sensitive Sp factor binding sites. J. Biol. Chem. 278, 29192-291200
18. Ma, P., Cui, X., Wang, S., Zhang, J., Nishanian, E. V., Wang, W., Wesley, R. A., and Danner, R. L. (2004) Nitric oxide posttranscriptionally up-regulates LPS-induced IL-8 expression through p38 MAPK activation. J. Leukoc. Biol. 76, 278-287
19. Kota, B. P., Huang, T. H., and Roufogalis, B. D. (2005) An overview on biological mechanisms of PPARs. Pharmacol. Res. 51, 85-94
20. Marx, N., Duez, H., Fruchart, J. C., and Staels, B. (2004) Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells. Circ. Res. 94, 1168-1178
21. Marx, N., Bourcier, T., Sukhova, G. K., Libby, P., and Plutzky, J. (1999) PPARgamma activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARgamma as a potential mediator in vascular disease. Arterioscler. Thromb. Vasc. Biol. 19, 546-551
22. Chen, Y. E., Fu, M., Zhang, J., Zhu, X., Lin, Y., Akinbami, M. A., and Song, Q. (2003) Peroxisome proliferator-activated receptors and the cardiovascular system. Vitam. Horm. 66, 157-188
23. Marx, N., Mach, F., Sauty, A., Leung, J. H., Sarafi, M. N., Ransohoff, R. M., Libby, P., Plutzky, J., and Luster, A. D. (2000) Peroxisome proliferator-activated receptor-gamma activators inhibit IFN-gamma-induced expression of the T cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells. J. Immunol. 164, 6503-6508
24. Inoue, I., Goto, S., Matsunaga, T., Nakajima, T., Awata, T., Hokari, S., Komoda, T., and Katayama, S. (2001) The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2, Zn2-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells. Metabolism 50, 3-11
25. Von Knethen, A., and Brune, B. (2002) Activation of peroxisome proliferator-activated receptor gamma by nitric oxide in monocytes/macrophages down-regulates p47phox and attenuates the respiratory burst. J. Immunol. 169, 2619-2626
26. Polikandriotis, J. A., Mazzella, L. J., Rupnow, H. L., and Hart, C. M. (2005) Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms. Arterioscler. Thromb. Vasc. Biol. 25, 1810-1816
27. Caballero, A. E., Saouaf, R., Lim, S. C., Hamdy, O., Abou-Elenin, K., O'Connor, C., Logerfo, F. W., Horton, E. S., and Veves, A. (2003) The effects of troglitazone, an insulin-sensitizing agent, on the endothelial function in early and late type 2 diabetes: a placebo-controlled randomized clinical trial. Metabolism 52, 173-180
28. Semple, R. K., Chatterjee, V. K., and O'Rahilly, S. (2006) PPARgamma and human metabolic disease. J. Clin. Invest. 116, 581-589
29. Delerive, P., Martin-Nizard, F., Chinetti, G., Trottein, F., Fruchart, J. C., Najib, J., Duriez, P., and Staels, B. (1999) Peroxisome proliferator-activated receptor activators inhibit thrombininduced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway. Circ. Res. 85, 394-402
30. Jackson, S. M., Parhami, F., Xi, X. P., Berliner, J. A., Hsueh, W. A., Law, R. E., and Demer, L. L. (1999) Peroxisome proliferator-activated receptor activators target human endothelial cells to inhibit leukocyte-endothelial cell interaction. Arterioscler. Thromb. Vasc. Biol. 19, 2094-2104
31. Yki-Jarvinen, H. (2004) Thiazolidinediones. N. Engl. J. Med. 351, 1106-1118
32. Hata, K., Nishimura, R., Ikeda, F., Yamashita, K., Matsubara, T., Nokubi, T., and Yoneda, T. (2003) Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor gamma during bone morphogenetic protein 2-induced adipogenesis. Mol. Biol. Cell 14, 545-555
33. Wang, W., Wang, S., Nishanian, E. V., Del Pilar Cintron, A., Wesley, R. A., and Danner, R. L. (2001) Signaling by eNOS through a superoxide-dependent p42/44 mitogen-activated protein kinase pathway. Am. J. Physiol. Cell Physiol. 281, C544-C554
34. Hu, E., Kim, J. B., Sarraf, P., and Spiegelman, B. M. (1996) Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma. Science 274, 2100-2103
35. Puigserver, P., Rhee, J., Lin, J., Wu, Z., Yoon, J. C., Zhang, C. Y., Krauss, S., Mootha, V. K., Lowell, B. B., and Spiegelman, B. M. (2001) Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. Mol. Cell 8, 971-982
36. Davis, R. J. (2000) Signal transduction by the JNK group of MAP kinases. Cell 103, 239-252
37. Schopfer, F. J., Lin, Y., Baker, P. R., Cui, T., Garcia-Barrio, M., Zhang, J., Chen, K., Chen, Y. E., and Freeman, B. A. (2005) Nitrolinoleic acid: an endogenous peroxisome proliferatoractivated receptor gamma ligand. Proc. Natl. Acad. Sci. U. S. A. 102, 2340-2345
38. Beckman, J. S. (1999) Parsing the effects of nitric oxide, S-nitrosothiols, and peroxynitrite on inducible nitric oxide synthase-dependent cardiac myocyte apoptosis. Circ. Res. 85, 870-871
39. Estevez, A. G., Spear, N., Manuel, S. M., Radi, R., Henderson, C. E., Barbeito, L., and Beckman, J. S. (1998) Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation. J. Neurosci. 18, 923-931
40. Wang, S., Zang, J., Theel, S., Barb, J. J., Munson, P. J., and Danner, R. L. (2006) Nitric Oxide Activation of Erk1/2 Regulates the Stability and Translation of mRNA Transcripts Containing CU-Rich Elements. Nucleic Acids Res. 34, 3044-3056
41. Pawliczak, R., Han, C., Huang, X. L., Demetris, A. J., Shelhamer, J. H., and Wu, T. (2002) 85-kDa cytosolic phospholipase A2 mediates peroxisome proliferator-activated receptor gamma activation in human lung epithelial cells. J. Biol. Chem. 277, 33153-33163
42. Pontsler, A. V., St Hilaire, A., Marathe, G. K., Zimmerman, G. A., and McIntyre, T. M. (2002) Cyclooxygenase-2 is induced in monocytes by peroxisome proliferator activated receptor gamma and oxidized alkyl phospholipids from oxidized low density lipoprotein. J. Biol. Chem. 277, 13029-13036
43. Pang, L., Nie, M., Corbett, L., and Knox, A. J. (2003) Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors. J. Immunol. 170, 1043-1051
44. Verrier, E., Wang, L., Wadham, C., Albanese, N., Hahn, C., Gamble, J. R., Chatterjee, V. K., Vadas, M. A., and Xia, P. (2004) PPARgamma agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: role of diacylglycerol kinase. Circ. Res. 94, 1515-1522
45. Zingarelli, B., Sheehan, M., Hake, P. W., O'Connor, M., Denenberg, A., and Cook, J. A. (2003) Peroxisome proliferator activator receptor-gamma ligands, 15-deoxy-Delta(12,14)-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways. J. Immunol. 171, 6827-6837
46. Bolego, C., Buccellati, C., Radaelli, T., Cetin, I., Puglisi, L., Folco, G., and Sala, A. (2006) eNOS, COX-2, and prostacyclin production are impaired in endothelial cells from diabetics. Biochem. Biophys. Res. Commun. 339, 188-190
47. Wang, N., Verna, L., Chen, N. G., Chen, J., Li, H., Forman, B. M., and Stemerman, M. B. (2002) Constitutive activation of peroxisome proliferator-activated receptor-gamma suppresses pro-inflammatory adhesion molecules in human vascular endothelial cells. J. Biol. Chem. 277, 34176-34181
48. Takata, Y., Kitami, Y., Yang, Z. H., Nakamura, M., Okura, T., and Hiwada, K. (2002) Vascular inflammation is negatively autoregulated by interaction between CCAAT/enhancer-binding protein-delta and peroxisome proliferator- activated receptorgamma. Circ. Res. 91, 427-433