메뉴 건너뛰기




Volumn 3, Issue 11, 2007, Pages 2037-2048

Lessons from "lower" organisms: What worms, flies, and zebrafish can teach US about human energy metabolism

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; SOMATOMEDIN;

EID: 37348999201     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0030199     Document Type: Review
Times cited : (145)

References (115)
  • 1
    • 34347245585 scopus 로고    scopus 로고
    • A nonadaptive scenario explaining the genetic predisposition to obesity: The "predation release" hypothesis
    • Speakman JR (2007) A nonadaptive scenario explaining the genetic predisposition to obesity: the "predation release" hypothesis. Cell Metab 6: 5-12.
    • (2007) Cell Metab , vol.6 , pp. 5-12
    • Speakman, J.R.1
  • 2
    • 20144363712 scopus 로고    scopus 로고
    • A potential decline in life expectancy in the United States in the 21st century
    • Olshansky SJ, Passaro DJ, Hershow RC, Layden J, Carnes BA, et al. (2005) A potential decline in life expectancy in the United States in the 21st century. N Engl J Med 352: 1138-1145.
    • (2005) N Engl J Med , vol.352 , pp. 1138-1145
    • Olshansky, S.J.1    Passaro, D.J.2    Hershow, R.C.3    Layden, J.4    Carnes, B.A.5
  • 4
    • 34047095297 scopus 로고    scopus 로고
    • The two TORCs and Akt
    • Bhaskar PT, Hay N (2007) The two TORCs and Akt. Dev Cell 12: 487-502.
    • (2007) Dev Cell , vol.12 , pp. 487-502
    • Bhaskar, P.T.1    Hay, N.2
  • 5
    • 34247140294 scopus 로고    scopus 로고
    • Role of insulin-like signalling in Drosophila lifespan
    • Giannakou ME, Partridge L (2007) Role of insulin-like signalling in Drosophila lifespan. Trends Biochem Sci 32: 180-188.
    • (2007) Trends Biochem Sci , vol.32 , pp. 180-188
    • Giannakou, M.E.1    Partridge, L.2
  • 6
    • 13944269223 scopus 로고    scopus 로고
    • The plasticity of aging: Insights from long-lived mutants
    • Kenyon C (2005) The plasticity of aging: insights from long-lived mutants. Cell 120: 449-460.
    • (2005) Cell , vol.120 , pp. 449-460
    • Kenyon, C.1
  • 7
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: Navigating downstream
    • Manning BD, Cantley LC (2007) AKT/PKB signaling: navigating downstream. Cell 129: 1261-1274.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 10
    • 34249657825 scopus 로고    scopus 로고
    • Bariatric surgery for morbid obesity
    • DeMaria EJ (2007) Bariatric surgery for morbid obesity. N Engl J Med 356: 2176-2183.
    • (2007) N Engl J Med , vol.356 , pp. 2176-2183
    • DeMaria, E.J.1
  • 11
    • 34548090763 scopus 로고    scopus 로고
    • Effects of bariatric surgery on mortality in Swedish obese subjects
    • Sjostrom L, Narbro K, Sjostrom CD, Karason K, Larsson B, et al. (2007) Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med 357: 741-752.
    • (2007) N Engl J Med , vol.357 , pp. 741-752
    • Sjostrom, L.1    Narbro, K.2    Sjostrom, C.D.3    Karason, K.4    Larsson, B.5
  • 12
    • 0022585682 scopus 로고
    • The autofluorescent "lipofuscin granules" in the intestinal cells of Caenorhabditis elegans are secondary lysosomes
    • Clokey GV, Jacobson LA (1986) The autofluorescent "lipofuscin granules" in the intestinal cells of Caenorhabditis elegans are secondary lysosomes. Mech Ageing Dev 35: 79-94.
    • (1986) Mech Ageing Dev , vol.35 , pp. 79-94
    • Clokey, G.V.1    Jacobson, L.A.2
  • 14
    • 27744446443 scopus 로고    scopus 로고
    • The ABC transporter PGP-2 from Caenorhabditis elegans is expressed in the sensory neuron pair AWA and contributes to lysosome formation and lipid storage within the intestine
    • Nunes F, Wolf M, Hartmann J, Paul RJ (2005) The ABC transporter PGP-2 from Caenorhabditis elegans is expressed in the sensory neuron pair AWA and contributes to lysosome formation and lipid storage within the intestine. Biochem Biophys Res Commun 338: 862-871.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 862-871
    • Nunes, F.1    Wolf, M.2    Hartmann, J.3    Paul, R.J.4
  • 15
    • 33947158693 scopus 로고    scopus 로고
    • Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle
    • Schroeder LK, Kremer S, Kramer MJ, Currie E, Kwan E, et al. (2007) Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle. Mol Biol Cell 18: 995-1008.
    • (2007) Mol Biol Cell , vol.18 , pp. 995-1008
    • Schroeder, L.K.1    Kremer, S.2    Kramer, M.J.3    Currie, E.4    Kwan, E.5
  • 16
    • 0037237117 scopus 로고    scopus 로고
    • C elegans: A model for exploring the genetics of fat storage
    • McKay RM, McKay JP, Avery L, Graff JM (2003) C elegans: a model for exploring the genetics of fat storage. Dev Cell 4: 131-142.
    • (2003) Dev Cell , vol.4 , pp. 131-142
    • McKay, R.M.1    McKay, J.P.2    Avery, L.3    Graff, J.M.4
  • 17
    • 0037448528 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
    • Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, et al. (2003) Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421: 268-272.
    • (2003) Nature , vol.421 , pp. 268-272
    • Ashrafi, K.1    Chang, F.Y.2    Watts, J.L.3    Fraser, A.G.4    Kamath, R.S.5
  • 18
    • 0032787396 scopus 로고    scopus 로고
    • Implication of tubby proteins as transcription factors by structure-based functional analysis
    • Boggon TJ, Shan WS, Santagata S, Myers SC, Shapiro L (1999) Implication of tubby proteins as transcription factors by structure-based functional analysis. Science 286: 2119-2125.
    • (1999) Science , vol.286 , pp. 2119-2125
    • Boggon, T.J.1    Shan, W.S.2    Santagata, S.3    Myers, S.C.4    Shapiro, L.5
  • 20
    • 0033609793 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of tub and its association with Src homology 2 domain-containing proteins implicate tub in intracellular signaling by insulin
    • Kapeller R, Moriarty A, Strauss A, Stubdal H, Theriault K, et al. (1999) Tyrosine phosphorylation of tub and its association with Src homology 2 domain-containing proteins implicate tub in intracellular signaling by insulin. J Biol Chem 274: 24980-24986.
    • (1999) J Biol Chem , vol.274 , pp. 24980-24986
    • Kapeller, R.1    Moriarty, A.2    Strauss, A.3    Stubdal, H.4    Theriault, K.5
  • 23
    • 0030813398 scopus 로고    scopus 로고
    • daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G (1997) daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942-946.
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 24
    • 0034613164 scopus 로고    scopus 로고
    • Regulation of C. elegans life-span by insulinlike signaling in the nervous system
    • Wolkow CA, Kimura KD, Lee MS, Ruvkun G (2000) Regulation of C. elegans life-span by insulinlike signaling in the nervous system. Science 290: 147-150.
    • (2000) Science , vol.290 , pp. 147-150
    • Wolkow, C.A.1    Kimura, K.D.2    Lee, M.S.3    Ruvkun, G.4
  • 25
    • 27244443371 scopus 로고    scopus 로고
    • Mukhopadhyay A, Deplancke B, Walhout AJ, Tissenbaum HA (2005) C. elegans tubby regulates life span and fat storage by two independent mechanisms. Cell Metab 2: 35-42.
    • Mukhopadhyay A, Deplancke B, Walhout AJ, Tissenbaum HA (2005) C. elegans tubby regulates life span and fat storage by two independent mechanisms. Cell Metab 2: 35-42.
  • 26
    • 0342680006 scopus 로고    scopus 로고
    • Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
    • Sze JY, Victor M, Loer C, Shi Y, Ruvkun G (2000) Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant. Nature 403: 560-564.
    • (2000) Nature , vol.403 , pp. 560-564
    • Sze, J.Y.1    Victor, M.2    Loer, C.3    Shi, Y.4    Ruvkun, G.5
  • 27
    • 34249891333 scopus 로고    scopus 로고
    • Two neurons mediate diet-restriction-induced longevity in C. elegans
    • Bishop NA, Guarente L (2007) Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature 447: 545-549.
    • (2007) Nature , vol.447 , pp. 545-549
    • Bishop, N.A.1    Guarente, L.2
  • 28
    • 34249888736 scopus 로고    scopus 로고
    • PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
    • Panowski SH, Wolff S, Aguilaniu H, Durieux J, Dillin A (2007) PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature 447: 550-555.
    • (2007) Nature , vol.447 , pp. 550-555
    • Panowski, S.H.1    Wolff, S.2    Aguilaniu, H.3    Durieux, J.4    Dillin, A.5
  • 29
    • 26444442036 scopus 로고    scopus 로고
    • A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49
    • Van Gilst MR, Hadjivassiliou H, Yamamoto KR (2005) A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Proc Natl Acad Sci U S A 102: 13496-13501.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13496-13501
    • Van Gilst, M.R.1    Hadjivassiliou, H.2    Yamamoto, K.R.3
  • 30
    • 15744386624 scopus 로고    scopus 로고
    • Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans
    • doi:10.1371/journal.pbio.0030053
    • Van Gilst MR, Hadjivassiliou H, Jolly A, Yamamoto KR (2005) Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans. PLoS Biol 3: e53. doi:10.1371/journal.pbio.0030053
    • (2005) PLoS Biol , vol.3
    • Van Gilst, M.R.1    Hadjivassiliou, H.2    Jolly, A.3    Yamamoto, K.R.4
  • 31
    • 22544480378 scopus 로고    scopus 로고
    • New hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis
    • Chakravarthy MV, Pan Z, Zhu Y, Tordjman K, Schneider JG, et al. (2005) "New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis. Cell Metab 1: 309-322.
    • (2005) Cell Metab , vol.1 , pp. 309-322
    • Chakravarthy, M.V.1    Pan, Z.2    Zhu, Y.3    Tordjman, K.4    Schneider, J.G.5
  • 32
    • 0023726860 scopus 로고
    • Maturation and degeneration of the fat body in the Drosophila larva and pupa as revealed by morphometric analysis
    • Butterworth FM, Emerson L, Rasch EM (1988) Maturation and degeneration of the fat body in the Drosophila larva and pupa as revealed by morphometric analysis. Tissue Cell 20: 255-268.
    • (1988) Tissue Cell , vol.20 , pp. 255-268
    • Butterworth, F.M.1    Emerson, L.2    Rasch, E.M.3
  • 33
    • 34247539980 scopus 로고    scopus 로고
    • The role of larval fat cells in adult Drosophila melanogaster
    • Aguila JR, Suszko J, Gibbs AG, Hoshizaki DK (2007) The role of larval fat cells in adult Drosophila melanogaster. J Exp Biol 210: 956-963.
    • (2007) J Exp Biol , vol.210 , pp. 956-963
    • Aguila, J.R.1    Suszko, J.2    Gibbs, A.G.3    Hoshizaki, D.K.4
  • 34
    • 33846481841 scopus 로고    scopus 로고
    • A role for the adult fat body in Drosophila male courtship behavior
    • doi:10.1371/journal.pgen.0030016
    • Lazareva AA, Roman G, Mattox W, Hardin PE, Dauwalder B (2007) A role for the adult fat body in Drosophila male courtship behavior. PLoS Genet 3:: e16. doi:10.1371/journal.pgen.0030016
    • (2007) PLoS Genet , vol.3
    • Lazareva, A.A.1    Roman, G.2    Mattox, W.3    Hardin, P.E.4    Dauwalder, B.5
  • 35
    • 0013415751 scopus 로고
    • Developmental physiology of the mutant female sterile(2)adipose of Drosophila melanogaster. I. Adult morphology, longevity, egg production, and egg lethality
    • Doane WW (1960) Developmental physiology of the mutant female sterile(2)adipose of Drosophila melanogaster. I. Adult morphology, longevity, egg production, and egg lethality. J Exp Zool 145: 1-21.
    • (1960) J Exp Zool , vol.145 , pp. 1-21
    • Doane, W.W.1
  • 36
    • 0037858382 scopus 로고
    • Developmental physiology of the mutant female sterile(2)adipose of Drosophila melanogaster. III. Corpus allatum-complex and ovarian transplantations
    • Doane WW (1961) Developmental physiology of the mutant female sterile(2)adipose of Drosophila melanogaster. III. Corpus allatum-complex and ovarian transplantations. J Exp Zool 146: 275-298.
    • (1961) J Exp Zool , vol.146 , pp. 275-298
    • Doane, W.W.1
  • 37
    • 0038569111 scopus 로고
    • Developmental physiology of the mutant female sterile(2)adipose of Drosophila melanogaster. II. Effects of altered environment and residual genome on its expression
    • Doane WW (1960) Developmental physiology of the mutant female sterile(2)adipose of Drosophila melanogaster. II. Effects of altered environment and residual genome on its expression. J Exp Zool 145: 23-41.
    • (1960) J Exp Zool , vol.145 , pp. 23-41
    • Doane, W.W.1
  • 39
    • 34548244121 scopus 로고    scopus 로고
    • Adipose is a conserved dosage-sensitive antiobesity gene
    • Suh JM, Zeve D, McKay R, Seo J, Salo Z, et al. (2007) Adipose is a conserved dosage-sensitive antiobesity gene. Cell Metab 6: 195-207.
    • (2007) Cell Metab , vol.6 , pp. 195-207
    • Suh, J.M.1    Zeve, D.2    McKay, R.3    Seo, J.4    Salo, Z.5
  • 40
    • 33748942837 scopus 로고    scopus 로고
    • Transcriptional control of adipocyte formation
    • Farmer SR (2006) Transcriptional control of adipocyte formation. Cell Metab 4: 263-273.
    • (2006) Cell Metab , vol.4 , pp. 263-273
    • Farmer, S.R.1
  • 41
    • 33845325476 scopus 로고    scopus 로고
    • Adipocyte differentiation from the inside out
    • Rosen ED, MacDougald OA (2006) Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 7: 885-896.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 885-896
    • Rosen, E.D.1    MacDougald, O.A.2
  • 42
    • 34447535560 scopus 로고    scopus 로고
    • SnapShot: Hedgehog signaling pathway
    • Chen M-H, Wilson CW, Chuang P-T (2007) SnapShot: Hedgehog signaling pathway Cell 130: 386.
    • (2007) Cell , vol.130 , pp. 386
    • Chen, M.-H.1    Wilson, C.W.2    Chuang, P.-T.3
  • 43
    • 33645046358 scopus 로고    scopus 로고
    • Hedgehog signaling plays a conserved role in inhibiting fat formation
    • Suh JM, Gao X, McKay J, McKay R, Salo Z, et al. (2006) Hedgehog signaling plays a conserved role in inhibiting fat formation. Cell Metab 3: 25-34.
    • (2006) Cell Metab , vol.3 , pp. 25-34
    • Suh, J.M.1    Gao, X.2    McKay, J.3    McKay, R.4    Salo, Z.5
  • 44
    • 0036868308 scopus 로고    scopus 로고
    • Increases in adipose and total body weight, but not in lean body mass, associated with subcutaneous administration of Sonic hedgehog-Ig fusion protein to mice
    • Martin P, Lane J, Pouliot L, Gains M, Stejskal R, et al. (2002) Increases in adipose and total body weight, but not in lean body mass, associated with subcutaneous administration of Sonic hedgehog-Ig fusion protein to mice. Drug Dev Res 57: 107-114.
    • (2002) Drug Dev Res , vol.57 , pp. 107-114
    • Martin, P.1    Lane, J.2    Pouliot, L.3    Gains, M.4    Stejskal, R.5
  • 45
    • 1542510700 scopus 로고    scopus 로고
    • Acquired and inherited lipodystrophies
    • Garg A (2004) Acquired and inherited lipodystrophies. N Engl J Med 350: 1220-1234.
    • (2004) N Engl J Med , vol.350 , pp. 1220-1234
    • Garg, A.1
  • 46
    • 0037052544 scopus 로고    scopus 로고
    • Ablation of insulin-producing neurons in flies: Growth and diabetic phenotypes
    • Rulifson EJ, Kim SK, Nusse R (2002) Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science 296: 1118-1120.
    • (2002) Science , vol.296 , pp. 1118-1120
    • Rulifson, E.J.1    Kim, S.K.2    Nusse, R.3
  • 47
    • 20044393471 scopus 로고    scopus 로고
    • Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands
    • Broughton SJ, Piper MD, Ikeya T, Bass TM, Jacobson J, et al. (2005) Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proc Natl Acad Sci U S A 102: 3105-3110.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 3105-3110
    • Broughton, S.J.1    Piper, M.D.2    Ikeya, T.3    Bass, T.M.4    Jacobson, J.5
  • 48
    • 33845543340 scopus 로고    scopus 로고
    • Control of metabolism and growth through insulin-like peptides in Drosophila
    • Geminard C, Arquier N, Layalle S, Bourouis M, Slaidina M, et al. (2006) Control of metabolism and growth through insulin-like peptides in Drosophila. Diabetes. 55: S5-8.
    • (2006) Diabetes , vol.55
    • Geminard, C.1    Arquier, N.2    Layalle, S.3    Bourouis, M.4    Slaidina, M.5
  • 49
    • 1542398216 scopus 로고    scopus 로고
    • Insect adipokinetic hormones: Release and integration of flight energy metabolism
    • Van der Horst DJ (2003) Insect adipokinetic hormones: release and integration of flight energy metabolism. Comp Biochem Physiol B Biochem Mol Biol 136: 217-226.
    • (2003) Comp Biochem Physiol B Biochem Mol Biol , vol.136 , pp. 217-226
    • Van der Horst, D.J.1
  • 50
    • 2942590660 scopus 로고    scopus 로고
    • Hemolymph sugar homeostasis and starvation-induced hyperactivity affected by genetic manipulations of the adipokinetic hormone-encoding gene in Drosophila melanogaster
    • Lee G, Park JH (2004) Hemolymph sugar homeostasis and starvation-induced hyperactivity affected by genetic manipulations of the adipokinetic hormone-encoding gene in Drosophila melanogaster. Genetics 167: 311-323.
    • (2004) Genetics , vol.167 , pp. 311-323
    • Lee, G.1    Park, J.H.2
  • 51
    • 4644242353 scopus 로고    scopus 로고
    • Conserved mechanisms of glucose sensing and regulation by Drosophila corpora cardiaca cells
    • Kim SK, Rulifson EJ (2004) Conserved mechanisms of glucose sensing and regulation by Drosophila corpora cardiaca cells. Nature 431: 316-320.
    • (2004) Nature , vol.431 , pp. 316-320
    • Kim, S.K.1    Rulifson, E.J.2
  • 52
    • 0037200026 scopus 로고    scopus 로고
    • Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium
    • Miura S, Gan JW, Brzostowski J, Parisi MJ, Schultz CJ, et al. (2002) Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium. J Biol Chem 277: 32253-32257.
    • (2002) J Biol Chem , vol.277 , pp. 32253-32257
    • Miura, S.1    Gan, J.W.2    Brzostowski, J.3    Parisi, M.J.4    Schultz, C.J.5
  • 54
    • 0141672132 scopus 로고    scopus 로고
    • Drosophila Perilipin/ADRP homologue Lsd2 regulates lipid metabolism
    • Teixeira L, Rabouille C, Rorth P, Ephrussi A, Vanzo NF (2003) Drosophila Perilipin/ADRP homologue Lsd2 regulates lipid metabolism. Mech Dev 120: 1071-1081.
    • (2003) Mech Dev , vol.120 , pp. 1071-1081
    • Teixeira, L.1    Rabouille, C.2    Rorth, P.3    Ephrussi, A.4    Vanzo, N.F.5
  • 55
    • 22744434906 scopus 로고    scopus 로고
    • Regulation of lipid-droplet transport by the perilipin homolog LSD2
    • Welte MA, Cermelli S, Griner J, Viera A, Guo Y, et al. (2005) Regulation of lipid-droplet transport by the perilipin homolog LSD2. Curr Biol 15: 1266-1275.
    • (2005) Curr Biol , vol.15 , pp. 1266-1275
    • Welte, M.A.1    Cermelli, S.2    Griner, J.3    Viera, A.4    Guo, Y.5
  • 57
    • 20744447492 scopus 로고    scopus 로고
    • Activation of the lipid droplet controls the rate of lipolysis of triglycerides in the insect fat body
    • Patel RT, Soulages JL, Hariharasundaram B, Arrese EL (2005) Activation of the lipid droplet controls the rate of lipolysis of triglycerides in the insect fat body. J Biol Chem 280: 22624-22631.
    • (2005) J Biol Chem , vol.280 , pp. 22624-22631
    • Patel, R.T.1    Soulages, J.L.2    Hariharasundaram, B.3    Arrese, E.L.4
  • 58
    • 34250306022 scopus 로고    scopus 로고
    • Dual lipolytic control of body fat storage and mobilization in Drosophila
    • doi:10.1371/journal.pbio.0050137
    • Gronke S, Muller G, Hirsch J, Fellert S, Andreou A, et al. (2007) Dual lipolytic control of body fat storage and mobilization in Drosophila. PLoS Biol 5:: e137. doi:10.1371/journal.pbio.0050137
    • (2007) PLoS Biol , vol.5
    • Gronke, S.1    Muller, G.2    Hirsch, J.3    Fellert, S.4    Andreou, A.5
  • 59
    • 33845900676 scopus 로고    scopus 로고
    • The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy
    • Fischer J, Lefevre C, Morava E, Mussini JM, Laforet P, et al. (2007) The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy. Nat Genet 39: 28-30.
    • (2007) Nat Genet , vol.39 , pp. 28-30
    • Fischer, J.1    Lefevre, C.2    Morava, E.3    Mussini, J.M.4    Laforet, P.5
  • 60
    • 33646462136 scopus 로고    scopus 로고
    • Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
    • Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, et al. (2006) Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 312: 734-737.
    • (2006) Science , vol.312 , pp. 734-737
    • Haemmerle, G.1    Lass, A.2    Zimmermann, R.3    Gorkiewicz, G.4    Meyer, C.5
  • 61
    • 26944489689 scopus 로고    scopus 로고
    • Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila
    • Gronke S, Mildner A, Fellert S, Tennagels N, Petry S, et al. (2005) Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila. Cell Metab 1: 323-330.
    • (2005) Cell Metab , vol.1 , pp. 323-330
    • Gronke, S.1    Mildner, A.2    Fellert, S.3    Tennagels, N.4    Petry, S.5
  • 62
    • 33846279755 scopus 로고    scopus 로고
    • Specialized hepatocyte-like cells regulate Drosophila lipid metabolism
    • Gutierrez E, Wiggins D, Fielding B, Gould AP (2007) Specialized hepatocyte-like cells regulate Drosophila lipid metabolism. Nature 445: 275-280.
    • (2007) Nature , vol.445 , pp. 275-280
    • Gutierrez, E.1    Wiggins, D.2    Fielding, B.3    Gould, A.P.4
  • 63
    • 12344292408 scopus 로고    scopus 로고
    • Developmental expression and nutritional regulation of a zebrafish gene homologous to mammalian microsomal triglyceride transfer protein large subunit
    • Marza E, Barthe C, Andre M, Villeneuve L, Helou C, et al. (2005) Developmental expression and nutritional regulation of a zebrafish gene homologous to mammalian microsomal triglyceride transfer protein large subunit. Dev Dyn 232: 506-518.
    • (2005) Dev Dyn , vol.232 , pp. 506-518
    • Marza, E.1    Barthe, C.2    Andre, M.3    Villeneuve, L.4    Helou, C.5
  • 64
    • 33845951203 scopus 로고    scopus 로고
    • Microsomal triglyceride transfer protein is required for yolk lipid utilization and absorption of dietary lipids in zebrafish larvae
    • Schlegel A, Stainier DY (2006) Microsomal triglyceride transfer protein is required for yolk lipid utilization and absorption of dietary lipids in zebrafish larvae. Biochemistry 45: 15179-15187.
    • (2006) Biochemistry , vol.45 , pp. 15179-15187
    • Schlegel, A.1    Stainier, D.Y.2
  • 66
    • 33746653423 scopus 로고    scopus 로고
    • Brock TJ, Browse J, Watts JL (2006) Genetic regulation of unsaturated fatty acid composition in C. elegans. PLoS Genet 2: e108. doi:10.1371/journal. pgen.0020108
    • Brock TJ, Browse J, Watts JL (2006) Genetic regulation of unsaturated fatty acid composition in C. elegans. PLoS Genet 2: e108. doi:10.1371/journal. pgen.0020108
  • 67
    • 34250759430 scopus 로고    scopus 로고
    • Fatty acid desaturation and the regulation of adiposity in Caenorhabditis elegans
    • Brock TJ, Browse J, Watts JL (2007) Fatty acid desaturation and the regulation of adiposity in Caenorhabditis elegans. Genetics 176: 865-875.
    • (2007) Genetics , vol.176 , pp. 865-875
    • Brock, T.J.1    Browse, J.2    Watts, J.L.3
  • 68
    • 0344198638 scopus 로고    scopus 로고
    • Site-1 protease is required for cartilage development in zebrafish
    • Schlombs K, Wagner T, Scheel J (2003) Site-1 protease is required for cartilage development in zebrafish. Proc Natl Acad Sci U S A 100: 14024-14029.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 14024-14029
    • Schlombs, K.1    Wagner, T.2    Scheel, J.3
  • 69
    • 0035907008 scopus 로고    scopus 로고
    • Genetic analysis of digestive physiology using fluorescent phospholipid reporters
    • Farber SA, Pack M, Ho SY, Johnson ID, Wagner DS, et al. (2001) Genetic analysis of digestive physiology using fluorescent phospholipid reporters. Science 292: 1385-1388.
    • (2001) Science , vol.292 , pp. 1385-1388
    • Farber, S.A.1    Pack, M.2    Ho, S.Y.3    Johnson, I.D.4    Wagner, D.S.5
  • 70
    • 33645569027 scopus 로고    scopus 로고
    • Zebrafish fat-free is required for intestinal lipid absorption and Golgi apparatus structure
    • Ho SY, Lorent K, Pack M, Farber SA (2006) Zebrafish fat-free is required for intestinal lipid absorption and Golgi apparatus structure. Cell Metab 3: 289-300.
    • (2006) Cell Metab , vol.3 , pp. 289-300
    • Ho, S.Y.1    Lorent, K.2    Pack, M.3    Farber, S.A.4
  • 71
    • 3042558661 scopus 로고    scopus 로고
    • Mutations affecting liver development and function in Medaka, Oryzias latipes, screened by multiple criteria
    • Watanabe T, Asaka S, Kitagawa D, Saito K, Kurashige R, et al. (2004) Mutations affecting liver development and function in Medaka, Oryzias latipes, screened by multiple criteria. Mech Dev 121: 791-802.
    • (2004) Mech Dev , vol.121 , pp. 791-802
    • Watanabe, T.1    Asaka, S.2    Kitagawa, D.3    Saito, K.4    Kurashige, R.5
  • 72
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning JD, Horton JD (2004) Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 114: 147-152.
    • (2004) J Clin Invest , vol.114 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 73
    • 24344452639 scopus 로고    scopus 로고
    • A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease
    • Sadler KC, Amsterdam A, Soroka C, Boyer J, Hopkins N (2005) A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease. Development 132: 3561-3572.
    • (2005) Development , vol.132 , pp. 3561-3572
    • Sadler, K.C.1    Amsterdam, A.2    Soroka, C.3    Boyer, J.4    Hopkins, N.5
  • 74
    • 32644473851 scopus 로고    scopus 로고
    • In vivo cell biology: Following the zebrafish trend
    • Beis D, Stainier DY (2006) In vivo cell biology: following the zebrafish trend. Trends Cell Biol 16: 105-112.
    • (2006) Trends Cell Biol , vol.16 , pp. 105-112
    • Beis, D.1    Stainier, D.Y.2
  • 75
    • 34247359602 scopus 로고    scopus 로고
    • Conditional targeted cell ablation in zebrafish: A new tool for regeneration studies
    • Curado S, Anderson RM, Jungblut B, Mumm J, Schroeter E, et al. (2007) Conditional targeted cell ablation in zebrafish: a new tool for regeneration studies. Dev Dyn 236: 1025-1035.
    • (2007) Dev Dyn , vol.236 , pp. 1025-1035
    • Curado, S.1    Anderson, R.M.2    Jungblut, B.3    Mumm, J.4    Schroeter, E.5
  • 76
    • 23644431709 scopus 로고    scopus 로고
    • TAZ, a transcriptional modulator of mesenchymal stem cell differentiation
    • Hong J-H, Hwang ES, McManus MT, Amsterdam A, Tian Y, et al. (2005) TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science 309: 1074-1078.
    • (2005) Science , vol.309 , pp. 1074-1078
    • Hong, J.-H.1    Hwang, E.S.2    McManus, M.T.3    Amsterdam, A.4    Tian, Y.5
  • 79
    • 34548756202 scopus 로고    scopus 로고
    • Regulating gene expression in zebrafish embryos using light-activated, negatively charged Peptide nucleic acids
    • Tang X, Maegawa S, Weinberg ES, Dmochowski IJ (2007) Regulating gene expression in zebrafish embryos using light-activated, negatively charged Peptide nucleic acids. J Am Chem Soc 129: 11000-11001.
    • (2007) J Am Chem Soc , vol.129 , pp. 11000-11001
    • Tang, X.1    Maegawa, S.2    Weinberg, E.S.3    Dmochowski, I.J.4
  • 80
    • 34250900443 scopus 로고    scopus 로고
    • Conserved sensory-neurosecretory cell types in annelid and fish forebrain: Insights into hypothalamus evolution
    • Tessmar-Raible K, Raible F, Christodoulou F, Guy K, Rembold M, et al. (2007) Conserved sensory-neurosecretory cell types in annelid and fish forebrain: insights into hypothalamus evolution. Cell 129: 1389-1400.
    • (2007) Cell , vol.129 , pp. 1389-1400
    • Tessmar-Raible, K.1    Raible, F.2    Christodoulou, F.3    Guy, K.4    Rembold, M.5
  • 81
    • 34548400363 scopus 로고    scopus 로고
    • Molecular genetics of pituitary development in zebrafish
    • Pogoda HM, Hammerschmidt M (2007) Molecular genetics of pituitary development in zebrafish. Semin Cell Dev Biol 18: 543-558.
    • (2007) Semin Cell Dev Biol , vol.18 , pp. 543-558
    • Pogoda, H.M.1    Hammerschmidt, M.2
  • 82
    • 34347380896 scopus 로고    scopus 로고
    • Creation of a genetic model of obesity in a teleost
    • Song Y, Cone RD (2007) Creation of a genetic model of obesity in a teleost. FASEB J 21: 2042-2049.
    • (2007) FASEB J , vol.21 , pp. 2042-2049
    • Song, Y.1    Cone, R.D.2
  • 84
    • 34548032087 scopus 로고    scopus 로고
    • Genome-wide association studies provide new insights into type 2 diabetes aetiology
    • Frayling TM (2007) Genome-wide association studies provide new insights into type 2 diabetes aetiology. Nat Rev Genet 8: 657-662.
    • (2007) Nat Rev Genet , vol.8 , pp. 657-662
    • Frayling, T.M.1
  • 85
    • 33845874637 scopus 로고    scopus 로고
    • Drug treatments for obesity: Orlistat, sibutramine, and rimonabant
    • Padwal RS, Majumdar SR (2007) Drug treatments for obesity: orlistat, sibutramine, and rimonabant. Lancet 369: 71-77.
    • (2007) Lancet , vol.369 , pp. 71-77
    • Padwal, R.S.1    Majumdar, S.R.2
  • 88
    • 0142042405 scopus 로고    scopus 로고
    • Lipophorin receptor-mediated lipoprotein endocytosis in insect fat body cells
    • Van Hoof D, Rodenburg KW, Van der Horst DJ (2003) Lipophorin receptor-mediated lipoprotein endocytosis in insect fat body cells. J Lipid Res 44: 1431-1440.
    • (2003) J Lipid Res , vol.44 , pp. 1431-1440
    • Van Hoof, D.1    Rodenburg, K.W.2    Van der Horst, D.J.3
  • 89
    • 0036860547 scopus 로고    scopus 로고
    • Insect lipoprotein follows a transferrin-like recycling pathway that is mediated by the insect LDL receptor homologue
    • Van Hoof D, Rodenburg KW, Van der Horst DJ (2002) Insect lipoprotein follows a transferrin-like recycling pathway that is mediated by the insect LDL receptor homologue. J Cell Sci 115: 4001-4012.
    • (2002) J Cell Sci , vol.115 , pp. 4001-4012
    • Van Hoof, D.1    Rodenburg, K.W.2    Van der Horst, D.J.3
  • 90
    • 33745108424 scopus 로고    scopus 로고
    • HNF factors form a network to regulate liver-enriched genes in zebrafish
    • Cheng W, Guo L, Zhang Z, Soo HM, Wen C, et al. (2006) HNF factors form a network to regulate liver-enriched genes in zebrafish. Dev Biol 294: 482-496.
    • (2006) Dev Biol , vol.294 , pp. 482-496
    • Cheng, W.1    Guo, L.2    Zhang, Z.3    Soo, H.M.4    Wen, C.5
  • 91
    • 0033083803 scopus 로고    scopus 로고
    • Crossregulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity
    • Wu Z, Rosen ED, Brun R, Hauser S, Adelmant G, et al. (1999) Crossregulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol Cell 3: 151-158.
    • (1999) Mol Cell , vol.3 , pp. 151-158
    • Wu, Z.1    Rosen, E.D.2    Brun, R.3    Hauser, S.4    Adelmant, G.5
  • 92
    • 33846343983 scopus 로고    scopus 로고
    • Dominantinterfering C/EBPalpha stimulates primitive erythropoiesis in zebrafish
    • Liu TX, Rhodes J, Deng M, Hsu K, Radomska HS, et al. (2007) Dominantinterfering C/EBPalpha stimulates primitive erythropoiesis in zebrafish. Exp Hematol 35: 230-239.
    • (2007) Exp Hematol , vol.35 , pp. 230-239
    • Liu, T.X.1    Rhodes, J.2    Deng, M.3    Hsu, K.4    Radomska, H.S.5
  • 94
    • 34548349302 scopus 로고    scopus 로고
    • Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor foxo1 in liver
    • Matsumoto M, Pocai A, Rossetti L, Depinho RA, Accili D (2007) Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor foxo1 in liver. Cell Metab 6: 208-216.
    • (2007) Cell Metab , vol.6 , pp. 208-216
    • Matsumoto, M.1    Pocai, A.2    Rossetti, L.3    Depinho, R.A.4    Accili, D.5
  • 95
    • 4143131139 scopus 로고    scopus 로고
    • Lightoid and Claret: A rab GTPase and its putative guanine nucleotide exchange factor in biogenesis of Drosophila eye pigment granules
    • Ma J, Plesken H, Treisman JE, Edelman-Novemsky I, Ren M (2004) Lightoid and Claret: A rab GTPase and its putative guanine nucleotide exchange factor in biogenesis of Drosophila eye pigment granules. Proc Natl Acad Sci U S A 101: 11652-11657.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 11652-11657
    • Ma, J.1    Plesken, H.2    Treisman, J.E.3    Edelman-Novemsky, I.4    Ren, M.5
  • 96
    • 13344277357 scopus 로고    scopus 로고
    • Early neonatal death in mice homozygous for a null allele of the insulin receptor gene
    • Accili D, Drago J, Lee EJ, Johnson MD, Cool MH, et al. (1996) Early neonatal death in mice homozygous for a null allele of the insulin receptor gene. Nat Genet 12: 106-109.
    • (1996) Nat Genet , vol.12 , pp. 106-109
    • Accili, D.1    Drago, J.2    Lee, E.J.3    Johnson, M.D.4    Cool, M.H.5
  • 97
    • 0033603208 scopus 로고    scopus 로고
    • Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4
    • Bohni R, Riesgo-Escovar J, Oldham S, Brogiolo W, Stocker H, et al. (1999) Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Cell 97: 865-875.
    • (1999) Cell , vol.97 , pp. 865-875
    • Bohni, R.1    Riesgo-Escovar, J.2    Oldham, S.3    Brogiolo, W.4    Stocker, H.5
  • 98
    • 0032555195 scopus 로고    scopus 로고
    • Knockout of the abetalipoproteinemia gene in mice: Reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes
    • Raabe M, Flynn LM, Zlot CH, Wong JS, Veniant MM, et al. (1998) Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes. Proc Natl Acad Sci U S A 95: 8686-8691.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8686-8691
    • Raabe, M.1    Flynn, L.M.2    Zlot, C.H.3    Wong, J.S.4    Veniant, M.M.5
  • 99
    • 0038143355 scopus 로고    scopus 로고
    • A Drosophila microsomal triglyceride transfer protein homolog promotes the assembly and secretion of human apolipoprotein B. Implications for human and insect transport and metabolism
    • Sellers JA, Hou L, Athar H, Hussain MM, Shelness GS (2003) A Drosophila microsomal triglyceride transfer protein homolog promotes the assembly and secretion of human apolipoprotein B. Implications for human and insect transport and metabolism. J Biol Chem 278: 20367-20373.
    • (2003) J Biol Chem , vol.278 , pp. 20367-20373
    • Sellers, J.A.1    Hou, L.2    Athar, H.3    Hussain, M.M.4    Shelness, G.S.5
  • 100
    • 34548399017 scopus 로고    scopus 로고
    • Insect lipoprotein biogenesis depends on an amphipathic beta cluster in apolipophorin II/I and is stimulated by microsomal triglyceride transfer protein
    • Smolenaars MM, de Morree A, Kerver J, Van der Horst DJ, Rodenburg KW (2007) Insect lipoprotein biogenesis depends on an amphipathic beta cluster in apolipophorin II/I and is stimulated by microsomal triglyceride transfer protein. J Lipid Res 48: 1955-1965.
    • (2007) J Lipid Res , vol.48 , pp. 1955-1965
    • Smolenaars, M.M.1    de Morree, A.2    Kerver, J.3    Van der Horst, D.J.4    Rodenburg, K.W.5
  • 101
    • 0034090310 scopus 로고    scopus 로고
    • Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha
    • Li J, Ning G, Duncan SA (2000) Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev 14: 464-474.
    • (2000) Genes Dev , vol.14 , pp. 464-474
    • Li, J.1    Ning, G.2    Duncan, S.A.3
  • 102
    • 16844366885 scopus 로고    scopus 로고
    • The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion
    • Gupta RK, Vatamaniuk MZ, Lee CS, Flaschen RC, Fulmer JT, et al. (2005) The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion. J Clin Invest 115: 1006-1015.
    • (2005) J Clin Invest , vol.115 , pp. 1006-1015
    • Gupta, R.K.1    Vatamaniuk, M.Z.2    Lee, C.S.3    Flaschen, R.C.4    Fulmer, J.T.5
  • 103
    • 0027393843 scopus 로고
    • The expression pattern of a Drosophila homolog to the mouse transcription factor HNF-4 suggests a determinative role in gut formation
    • Zhong W, Sladek FM, Darnell JE Jr. (1993) The expression pattern of a Drosophila homolog to the mouse transcription factor HNF-4 suggests a determinative role in gut formation. EMBO J 12: 537-544.
    • (1993) EMBO J , vol.12 , pp. 537-544
    • Zhong, W.1    Sladek, F.M.2    Darnell Jr., J.E.3
  • 104
    • 33750332589 scopus 로고    scopus 로고
    • Dynamic regulation of Drosophila nuclear receptor activity in vivo
    • Palanker L, Necakov AS, Sampson HM, Ni R, Hu C, et al. (2006) Dynamic regulation of Drosophila nuclear receptor activity in vivo. Development 133: 3549-3562.
    • (2006) Development , vol.133 , pp. 3549-3562
    • Palanker, L.1    Necakov, A.S.2    Sampson, H.M.3    Ni, R.4    Hu, C.5
  • 105
    • 0037440454 scopus 로고    scopus 로고
    • Formation of the digestive system in zebrafish. I. Liver morphogenesis
    • Field HA, Ober EA, Roeser T, Stainier DY (2003) Formation of the digestive system in zebrafish. I. Liver morphogenesis. Dev Biol 253: 279-290.
    • (2003) Dev Biol , vol.253 , pp. 279-290
    • Field, H.A.1    Ober, E.A.2    Roeser, T.3    Stainier, D.Y.4
  • 106
    • 20444386267 scopus 로고    scopus 로고
    • Bresolin T, de Freitas Rebelo M, Celso Dias Bainy A (2005) Expression of PXR, CYP3A and MDR1 genes in liver of zebrafish. Comp Biochem Physiol C Toxicol Pharmacol 140: 403-407.
    • Bresolin T, de Freitas Rebelo M, Celso Dias Bainy A (2005) Expression of PXR, CYP3A and MDR1 genes in liver of zebrafish. Comp Biochem Physiol C Toxicol Pharmacol 140: 403-407.
  • 107
    • 0030829812 scopus 로고    scopus 로고
    • Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene
    • Shimano H, Shimomura I, Hammer RE, Herz J, Goldstein JL, et al. (1997) Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene. J Clin Invest 100: 2115-2124.
    • (1997) J Clin Invest , vol.100 , pp. 2115-2124
    • Shimano, H.1    Shimomura, I.2    Hammer, R.E.3    Herz, J.4    Goldstein, J.L.5
  • 108
    • 33744544947 scopus 로고    scopus 로고
    • Fatty acid auxotrophy in Drosophila larvae lacking SREBP. Cell
    • Kunte AS, Matthews KA, Rawson RB (2006) Fatty acid auxotrophy in Drosophila larvae lacking SREBP. Cell Metab 3: 439-448.
    • (2006) Metab , vol.3 , pp. 439-448
    • Kunte, A.S.1    Matthews, K.A.2    Rawson, R.B.3
  • 111
    • 0242353392 scopus 로고    scopus 로고
    • cDNA nucleotide sequence coding for stearoyl-CoA desaturase and its expression in the zebrafish (Danio rerio) embryo
    • Hsieh SL, Liu RW, Wu CH, Cheng WT, Kuo CM (2003) cDNA nucleotide sequence coding for stearoyl-CoA desaturase and its expression in the zebrafish (Danio rerio) embryo. Mol Reprod Dev 66: 325-333.
    • (2003) Mol Reprod Dev , vol.66 , pp. 325-333
    • Hsieh, S.L.1    Liu, R.W.2    Wu, C.H.3    Cheng, W.T.4    Kuo, C.M.5
  • 112
    • 33846444928 scopus 로고    scopus 로고
    • The cationic amino acid transporters CAT1 and CAT3 mediate NMDA receptor activation-dependent changes in elaboration of neuronal processes via the mammalian target of rapamycin mTOR pathway
    • Huang Y, Kang BN, Tian J, Liu Y, Luo HR, et al. (2007) The cationic amino acid transporters CAT1 and CAT3 mediate NMDA receptor activation-dependent changes in elaboration of neuronal processes via the mammalian target of rapamycin mTOR pathway. J Neurosci 27: 449-458.
    • (2007) J Neurosci , vol.27 , pp. 449-458
    • Huang, Y.1    Kang, B.N.2    Tian, J.3    Liu, Y.4    Luo, H.R.5
  • 113
    • 0036768370 scopus 로고    scopus 로고
    • Structure and expression patterns of Drosophila TULP and TUSP, members of the tubby-like gene family
    • Ronshaugen M, McGinnis N, Inglis D, Chou D, Zhao J, et al. (2002) Structure and expression patterns of Drosophila TULP and TUSP, members of the tubby-like gene family. Mech Dev 117: 209-215.
    • (2002) Mech Dev , vol.117 , pp. 209-215
    • Ronshaugen, M.1    McGinnis, N.2    Inglis, D.3    Chou, D.4    Zhao, J.5
  • 114
    • 34248149018 scopus 로고    scopus 로고
    • Larval zebrafish as a model for glucose metabolism: Expression of phosphoenolpyruvate carboxykinase as a marker for exposure to anti-diabetic compounds
    • Elo B, Villano CM, Govorko D, White LA (2007) Larval zebrafish as a model for glucose metabolism: expression of phosphoenolpyruvate carboxykinase as a marker for exposure to anti-diabetic compounds. J Mol Endocrinol 38: 433-440.
    • (2007) J Mol Endocrinol , vol.38 , pp. 433-440
    • Elo, B.1    Villano, C.M.2    Govorko, D.3    White, L.A.4
  • 115
    • 15244344019 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptors in zebrafish (Danio rerio) depending on gender and developmental stage
    • Ibabe A, Bilbao E, Cajaraville MP (2005) Expression of peroxisome proliferator-activated receptors in zebrafish (Danio rerio) depending on gender and developmental stage. Histochem Cell Biol 123: 75-87.
    • (2005) Histochem Cell Biol , vol.123 , pp. 75-87
    • Ibabe, A.1    Bilbao, E.2    Cajaraville, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.