Dominant-interfering C/EBPα stimulates primitive erythropoiesis in zebrafish

Experimental Hematology

Volumn 35, Issue 2, 2007, Pages 230-239

  Liu, Ting Xi ^a,c   Rhodes, Jennifer ^a   Deng, Min ^a   Hsu, Karl ^a   Radomska, Hanna S ^b   Kanki, John P ^a   Tenen, Daniel G ^b   Look, A Thomas ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c SHANGHAI UNIVERSITY OF MEDICINE AND HEALTH SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; ISOPROTEIN; MESSENGER RNA; PROTEIN; PROTEIN CEBPA; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL LINE; CELL MATURATION; CONTROLLED STUDY; DELETION MUTANT; EMBRYO DEVELOPMENT; ERYTHROPOIESIS; EVALUATION; FERTILIZATION; GENE EXPRESSION; GENE REPRESSION; GRANULOCYTE; GRANULOPOIESIS; IN SITU HYBRIDIZATION; IN VITRO STUDY; MESODERM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TRANSCRIPTION INITIATION; ZEBRA FISH;

ANIMALS; BASE SEQUENCE; BLOOD VESSELS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; DNA, COMPLEMENTARY; EMBRYONIC DEVELOPMENT; ERYTHROPOIESIS; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, DOMINANT; HEMATOPOIETIC STEM CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; TRANSLOCATION, GENETIC; TRANSPLANTATION, HETEROLOGOUS; ZEBRAFISH;

DANIO RERIO;

EID: 33846343983     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2006.10.008     Document Type: Article

References (39)

1. Hohaus S., Petrovick M.S., Voso M.T., Sun Z., Zhang D.E., and Tenen D.G. PU.1 (Spi-1) and C/EBPα regulate expression of the granulocyte-macrophage colony-stimulating factor receptor α gene. Mol Cell Biol 15 (1995) 5830-5845
2. Radomska H.S., Huettner C.S., Zhang P., Cheng T., Scadden D.T., and Tenen D.G. CCAAT/enhancer binding protein α is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors. Mol Cell Biol 18 (1998) 4301-4314
3. Scott L.M., Civin C.I., Rorth P., and Friedman A.D. A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells. Blood 80 (1992) 1725-1735
4. Akashi K., Traver D., Miyamoto T., and Weissman I.L. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404 (2000) 193-197
5. Wang X., Scott E., Sawyers C.L., and Friedman A.D. C/EBPα bypasses granulocyte colony-stimulating factor signals to rapidly induce PU.1 gene expression, stimulate granulocytic differentiation, and limit proliferation in 32D cl3 myeloblasts. Blood 94 (1999) 560-571
6. Zhang D.E., Zhang P., Wang N.D., Hetherington C.J., Darlington G.J., and Tenen D.G. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice. Proc Natl Acad Sci U S A 94 (1997) 569-574
7. Wagner K., Zhang P., Rosenbauer F., et al. Absence of the transcription factor CCAAT enhancer binding protein α results in loss of myeloid identity in bcr/abl-induced malignancy. Proc Natl Acad Sci U S A 103 (2006) 6338-6343
8. Pabst T., Mueller B.U., Zhang P., et al. Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia. Nat Genet 27 (2001) 263-270
9. Schwieger M., Lohler J., Fischer M., Herwig U., Tenen D.G., and Stocking C. A dominant-negative mutant of C/EBPα, associated with acute myeloid leukemias, inhibits differentiation of myeloid and erythroid progenitors of man but not mouse. Blood 103 (2004) 2744-2752
10. Amatruda J.F., and Zon L.I. Dissecting hematopoiesis and disease using the zebrafish. Dev Biol 216 (1999) 1-15
11. Zon L.I. Zebrafish: a new model for human disease. Genome Res 9 (1999) 99-100
12. Lieschke G.J., Oates A.C., Paw B.H., et al. Zebrafish SPI-1 (PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning. Dev Biol 246 (2002) 274-295
13. Shepard J.L., and Zon L.I. Developmental derivation of embryonic and adult macrophages. Curr Opin Hematol 7 (2000) 3-8
14. Herbomel P., Thisse B., and Thisse C. Ontogeny and behaviour of early macrophages in the zebrafish embryo. Development 126 (1999) 3735-3745
15. Kimmel C.B., Warga R.M., and Schilling T.F. Origin and organization of the zebrafish fate map. Development 108 (1990) 581-594
16. Warga R.M., and Nusslein-Volhard C. Origin and development of the zebrafish endoderm. Development 126 (1999) 827-838
17. Detrich III H.W., Kieran M.W., Chan F.Y., et al. Intraembryonic hematopoietic cell migration during vertebrate development. Proc Natl Acad Sci U S A 92 (1995) 10713-10717
18. Thompson M.A., Ransom D.G., Pratt S.J., et al. The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis. Dev Biol 197 (1998) 248-269
19. Bennett C.M., Kanki J.P., Rhodes J., et al. Myelopoiesis in the zebrafish, Danio rerio. Blood 98 (2001) 643-651
20. Lyons S.E., Shue B.C., Oates A.C., Zon L.I., and Liu P.P. A novel myeloid-restricted zebrafish CCAAT/enhancer-binding protein with a potent transcriptional activation domain. Blood 97 (2001) 2611-2617
21. Rhodes J., Hagen A., Hsu K., et al. Interplay of pu.1 and gata1 determines myelo-erythroid progenitor cell fate in zebrafish. Dev Cell 8 (2005) 97-108
22. Kimmel C.B., Ballard W.W., Kimmel S.R., Ullmann B., and Schilling T.F. Stages of embryonic development of the zebrafish. Dev Dyn 203 (1995) 253-310
23. Westerfield M. The zebrafish book. A guide for the laboratory use of zebrafish Danio (Brachydanio) rerio (1993), Institute of Neuroscience University of Oregon, Eugene, OR
24. Liu T.X., Zhou Y., Kanki J.P., et al. Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies. Proc Natl Acad Sci U S A 99 (2002) 6136-6141
25. Lyons S.E., Shue B.C., Lei L., Oates A.C., Zon L.I., and Liu P.P. Molecular cloning, genetic mapping, and expression analysis of four zebrafish c/ebp genes. Gene 281 (2001) 43-51
26. Nerlov C., and Ziff E.B. Three levels of functional interaction determine the activity of CCAAT/enhancer binding protein-α on the serum albumin promoter. Genes Dev 8 (1994) 350-362
27. Smith L.T., Hohaus S., Gonzalez D.A., Dziennis S.E., and Tenen D.G. PU.1 (Spi-1) and C/EBP α regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells. Blood 88 (1996) 1234-1247
28. Liao E.C., Paw B.H., Oates A.C., Pratt S.J., Postlethwait J.H., and Zon L.I. SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish. Genes Dev 12 (1998) 621-626
29. Stainier D.Y., Weinstein B.M., Detrich III H.W., Zon L.I., and Fishman M.C. Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages. Development 121 (1995) 3141-3150
30. Gering M., Rodaway A.R., Gottgens B., Patient R.K., and Green A.R. The SCL gene specifies haemangioblast development from early mesoderm. EMBO J 17 (1998) 4029-4045
31. Calkhoven C.F., Muller C., and Leutz A. Translational control of gene expression and disease. Trends Mol Med 8 (2002) 577-583
32. Calkhoven C.F., Muller C., Martin R., et al. Translational control of SCL-isoform expression in hematopoietic lineage choice. Genes Dev 17 (2003) 959-964
33. Wechsler J., Greene M., McDevitt M.A., et al. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet 32 (2002) 148-152
34. Li Z., Godinho F.J., Klusmann J.H., Garriga-Canut M., Yu C., and Orkin S.H. Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. Nat Genet 37 (2005) 613-619
35. Tenen D.G., Hromas R., Licht J.D., and Zhang D.E. Transcription factors, normal myeloid development, and leukemia. Blood 90 (1997) 489-519
36. + cells. Blood 101 (2003) 2206-2214
37. + human marrow cells in vitro. Br J Haematol 127 (2004) 451-463
38. Rekhtman N., Radparvar F., Evans T., and Skoultchi A.I. Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells. Genes Dev 13 (1999) 1398-1411
39. Moreau-Gachelin F., Tavitian A., and Tambourin P. Spi-1 is a putative oncogene in virally induced murine erythroleukaemias. Nature 331 (1988) 277-280