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Volumn 3, Issue 2, 2005, Pages 0301-0312

Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans

Author keywords

[No Author keywords available]

Indexed keywords

FAT; FATTY ACID; HORMONE RECEPTOR; NUCLEAR HORMONE RECEPTOR 49; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; UNCLASSIFIED DRUG;

EID: 15744386624     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0030053     Document Type: Article
Times cited : (332)

References (35)
  • 1
    • 0035976638 scopus 로고    scopus 로고
    • Nuclear receptors and lipid physiology: Opening the X-files
    • Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ (2001) Nuclear receptors and lipid physiology: Opening the X-files. Science 294: 1866-1870.
    • (2001) Science , vol.294 , pp. 1866-1870
    • Chawla, A.1    Repa, J.J.2    Evans, R.M.3    Mangelsdorf, D.J.4
  • 2
    • 1942518840 scopus 로고    scopus 로고
    • PPARs and the complex journey to obesity
    • Evans RM, Barish GD, Wang YX (2004) PPARs and the complex journey to obesity. Nat Med 10: 355-361.
    • (2004) Nat Med , vol.10 , pp. 355-361
    • Evans, R.M.1    Barish, G.D.2    Wang, Y.X.3
  • 3
    • 0036851863 scopus 로고    scopus 로고
    • The liver X receptor gene team: Potential new players in atherosclerosis
    • Repa JJ, Mangelsdorf DJ (2002) The liver X receptor gene team: Potential new players in atherosclerosis. Nat Med 8: 1243-1248.
    • (2002) Nat Med , vol.8 , pp. 1243-1248
    • Repa, J.J.1    Mangelsdorf, D.J.2
  • 4
    • 0035224757 scopus 로고    scopus 로고
    • Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes
    • RESEARCH0029
    • Maglich JM, Sluder A, Guan X, Shi Y, McKee DD, et al. (2001) Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes. Genome Biol 2: RESEARCH0029.
    • (2001) Genome Biol , vol.2
    • Maglich, J.M.1    Sluder, A.2    Guan, X.3    Shi, Y.4    McKee, D.D.5
  • 5
    • 0033053181 scopus 로고    scopus 로고
    • The nuclear receptor superfamily has undergone extensive proliferation and diversification in nematodes
    • Sluder AE, Mathews SW, Hough D, Yin VP, Maina CV (1999) The nuclear receptor superfamily has undergone extensive proliferation and diversification in nematodes. Genome Res 9: 103-120.
    • (1999) Genome Res , vol.9 , pp. 103-120
    • Sluder, A.E.1    Mathews, S.W.2    Hough, D.3    Yin, V.P.4    Maina, C.V.5
  • 6
    • 4944258189 scopus 로고    scopus 로고
    • Evolutionary genomics of nuclear receptors: From 25 ancestral genes to derived endocrine systems
    • Bertrand S, Brunet FG, Escriva H, Parmentier G, Laudet V, et al. (2004) Evolutionary genomics of nuclear receptors: From 25 ancestral genes to derived endocrine systems. Mol Biol Evol 21: 1923-1937.
    • (2004) Mol Biol Evol , vol.21 , pp. 1923-1937
    • Bertrand, S.1    Brunet, F.G.2    Escriva, H.3    Parmentier, G.4    Laudet, V.5
  • 7
    • 0347761358 scopus 로고    scopus 로고
    • Expression and function of conserved nuclear receptor genes in Caenorhabditis elegans
    • Gissendanner CR, Crossgrove K, Kraus KA, Maina CV, Sluder AE (2004) Expression and function of conserved nuclear receptor genes in Caenorhabditis elegans. Dev Biol 266: 399-416.
    • (2004) Dev Biol , vol.266 , pp. 399-416
    • Gissendanner, C.R.1    Crossgrove, K.2    Kraus, K.A.3    Maina, C.V.4    Sluder, A.E.5
  • 9
    • 0038241793 scopus 로고    scopus 로고
    • HNF4: A central regulator of hepatocyte differentiation and function
    • Watt AJ, Garrison WD, Duncan SA (2003) HNF4: A central regulator of hepatocyte differentiation and function. Hepatology 37: 1249-1253.
    • (2003) Hepatology , vol.37 , pp. 1249-1253
    • Watt, A.J.1    Garrison, W.D.2    Duncan, S.A.3
  • 10
    • 0032857154 scopus 로고    scopus 로고
    • High-throughput isolation of Caenorhabditis elegans deletion mutants
    • Liu LX, Spoerke JM, Mulligan EL, Chen J, Reardon B, et al. (1999) High-throughput isolation of Caenorhabditis elegans deletion mutants. Genome Res 9: 859-867.
    • (1999) Genome Res , vol.9 , pp. 859-867
    • Liu, L.X.1    Spoerke, J.M.2    Mulligan, E.L.3    Chen, J.4    Reardon, B.5
  • 11
    • 0037167855 scopus 로고    scopus 로고
    • Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans
    • Herndon LA, Schmeissner PJ, Dudaronek JM, Brown PA, Listner KM, et al. (2002) Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 419: 808-814.
    • (2002) Nature , vol.419 , pp. 808-814
    • Herndon, L.A.1    Schmeissner, P.J.2    Dudaronek, J.M.3    Brown, P.A.4    Listner, K.M.5
  • 12
    • 0037448528 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
    • Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, et al. (2003) Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421: 268-272.
    • (2003) Nature , vol.421 , pp. 268-272
    • Ashrafi, K.1    Chang, F.Y.2    Watts, J.L.3    Fraser, A.G.4    Kamath, R.S.5
  • 13
    • 0035827706 scopus 로고    scopus 로고
    • Mitochondrial expression and function of GAS-1 in Caenorhabditis elegans
    • Kayser EB, Morgan PG, Hoppel CL, Sedensky MM (2001) Mitochondrial expression and function of GAS-1 in Caenorhabditis elegans. J Biol Chem 276: 20551-20558.
    • (2001) J Biol Chem , vol.276 , pp. 20551-20558
    • Kayser, E.B.1    Morgan, P.G.2    Hoppel, C.L.3    Sedensky, M.M.4
  • 14
    • 0034720457 scopus 로고    scopus 로고
    • A palmitoyl-CoA-specific delta9 fatty acid desaturase from Caenorhabditis elegans
    • Watts JL, Browse J (2000) A palmitoyl-CoA-specific delta9 fatty acid desaturase from Caenorhabditis elegans. Biochem Biophys Res Commun 272: 263-269.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 263-269
    • Watts, J.L.1    Browse, J.2
  • 15
    • 0029077405 scopus 로고
    • The regulation of stearoyl-CoA desaturase (SCD)
    • Ntambi JM (1995) The regulation of stearoyl-CoA desaturase (SCD). Prog Lipid Res 34: 139-150.
    • (1995) Prog Lipid Res , vol.34 , pp. 139-150
    • Ntambi, J.M.1
  • 16
    • 2342652187 scopus 로고    scopus 로고
    • Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver
    • Dobrzyn P, Dobrzyn A, Miyazaki M, Cohen P, Asilmaz E, et al. (2004) Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver. Proc Natl Acad Sci U S A 101: 6409-6414.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6409-6414
    • Dobrzyn, P.1    Dobrzyn, A.2    Miyazaki, M.3    Cohen, P.4    Asilmaz, E.5
  • 17
    • 0037197901 scopus 로고    scopus 로고
    • Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans
    • Watts JL, Browse J (2002) Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans. Proc Natl Acad Sci U S A 99: 5854-5859.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 5854-5859
    • Watts, J.L.1    Browse, J.2
  • 18
    • 0030885712 scopus 로고    scopus 로고
    • Fatty acid activation
    • Watkins PA (1997) Fatty acid activation. Prog Lipid Res 36: 55-83.
    • (1997) Prog Lipid Res , vol.36 , pp. 55-83
    • Watkins, P.A.1
  • 19
    • 0036321931 scopus 로고    scopus 로고
    • Do long-chain acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways?
    • Coleman RA, Lewin TM, Van Horn CG, Gonzalez-Baro MR (2002) Do long-chain acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways? J Nutr 132: 2123-2126.
    • (2002) J Nutr , vol.132 , pp. 2123-2126
    • Coleman, R.A.1    Lewin, T.M.2    Van Horn, C.G.3    Gonzalez-Baro, M.R.4
  • 20
    • 0036828603 scopus 로고    scopus 로고
    • Molecular mechanisms linking calorie restriction and longevity
    • Merry BJ (2002) Molecular mechanisms linking calorie restriction and longevity. Int J Biochem Cell Biol 34: 1340-1354.
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1340-1354
    • Merry, B.J.1
  • 21
    • 0042092531 scopus 로고    scopus 로고
    • Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
    • Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, et al. (2003) Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424: 277-283.
    • (2003) Nature , vol.424 , pp. 277-283
    • Murphy, C.T.1    McCarroll, S.A.2    Bargmann, C.I.3    Fraser, A.4    Kamath, R.S.5
  • 22
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • Desvergne B, Wahli W (1999) Peroxisome proliferator-activated receptors: Nuclear control of metabolism. Endocr Rev 20: 649-688.
    • (1999) Endocr Rev , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 23
    • 0037453718 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor delta activates fat metabolism to prevent obesity
    • Wang YX, Lee CH, Tiep S, Yu RT, Ham J, et al. (2003) Peroxisome- proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell 113: 159-170.
    • (2003) Cell , vol.113 , pp. 159-170
    • Wang, Y.X.1    Lee, C.H.2    Tiep, S.3    Yu, R.T.4    Ham, J.5
  • 24
    • 0032491614 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis
    • Costet P, Legendre C, More J, Edgar A, Galtier P, et al. (1998) Peroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis. J Biol Chem 273: 29577-29585.
    • (1998) J Biol Chem , vol.273 , pp. 29577-29585
    • Costet, P.1    Legendre, C.2    More, J.3    Edgar, A.4    Galtier, P.5
  • 25
    • 0032871502 scopus 로고    scopus 로고
    • Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol
    • Ntambi JM (1999) Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol. J Lipid Res 40: 1549-1558.
    • (1999) J Lipid Res , vol.40 , pp. 1549-1558
    • Ntambi, J.M.1
  • 26
    • 0036790520 scopus 로고    scopus 로고
    • The function of leptin in nutrition, weight, and physiology
    • Friedman JM (2002) The function of leptin in nutrition, weight, and physiology. Nutr Rev 60: S1-S14; discussion S68-S84, S85-S87.
    • (2002) Nutr Rev , vol.60
    • Friedman, J.M.1
  • 28
    • 0032489437 scopus 로고    scopus 로고
    • Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha)
    • Aoyama T, Peters JM, Iritani N, Nakajima T, Furihata K, et al. (1998) Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha). J Biol Chem 273: 5678-5684.
    • (1998) J Biol Chem , vol.273 , pp. 5678-5684
    • Aoyama, T.1    Peters, J.M.2    Iritani, N.3    Nakajima, T.4    Furihata, K.5
  • 29
    • 4544231849 scopus 로고    scopus 로고
    • Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha
    • Miyazaki M, Dobrzyn A, Sampath H, Lee SH, Man WC, et al. (2004) Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha. J Biol Chem 279: 35017-35024.
    • (2004) J Biol Chem , vol.279 , pp. 35017-35024
    • Miyazaki, M.1    Dobrzyn, A.2    Sampath, H.3    Lee, S.H.4    Man, W.C.5
  • 30
    • 0037063997 scopus 로고    scopus 로고
    • Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand
    • Dhe-Paganon S, Duda K, Iwamoto M, Chi YI, Shoelson SE (2002) Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand. J Biol Chem 277: 37973-37976.
    • (2002) J Biol Chem , vol.277 , pp. 37973-37976
    • Dhe-Paganon, S.1    Duda, K.2    Iwamoto, M.3    Chi, Y.I.4    Shoelson, S.E.5
  • 31
    • 0036710140 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids
    • Wisely GB, Miller AB, Davis RG, Thornquest AD Jr, Johnson R, et al. (2002) Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids. Structure 10: 1225-1234.
    • (2002) Structure , vol.10 , pp. 1225-1234
    • Wisely, G.B.1    Miller, A.B.2    Davis, R.G.3    Thornquest Jr., A.D.4    Johnson, R.5
  • 32
    • 0037448540 scopus 로고    scopus 로고
    • Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
    • Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-237.
    • (2003) Nature , vol.421 , pp. 231-237
    • Kamath, R.S.1    Fraser, A.G.2    Dong, Y.3    Poulin, G.4    Durbin, R.5
  • 33
    • 0033609291 scopus 로고    scopus 로고
    • Signals from the reproductive system regulate the lifespan of C. elegans
    • Hsin H, Kenyon C (1999) Signals from the reproductive system regulate the lifespan of C. elegans. Nature 399: 362-366.
    • (1999) Nature , vol.399 , pp. 362-366
    • Hsin, H.1    Kenyon, C.2
  • 34
    • 0034697980 scopus 로고    scopus 로고
    • Predicting subcellular localization of proteins based on their N-terminal amino acid sequence
    • Emanuelsson O, Nielsen H, Brunak S, von Heijne G (2000) Predicting subcellular localization of proteins based on their N-terminal amino acid sequence. J Mol Biol 300: 1005-1016.
    • (2000) J Mol Biol , vol.300 , pp. 1005-1016
    • Emanuelsson, O.1    Nielsen, H.2    Brunak, S.3    Von Heijne, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.