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Volumn 78, Issue 3 SUPPL., 2007, Pages

Role of adipose tissue in the development of vascular complications in type 2 diabetes mellitus

Author keywords

Adipocytokines; Cardiovascular complications; Type 2 diabetes mellitus

Indexed keywords

ADIPONECTIN; ANGIOTENSINOGEN; CYTOKINE; FATTY ACID; LEPTIN; MONOCYTE CHEMOTACTIC PROTEIN; RESISTIN; RETINOID BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA; VISFATIN;

EID: 36549041940     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2007.10.007     Document Type: Article
Times cited : (14)

References (113)
  • 1
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet P., Alberti K.G., and Shaw J. Global and societal implications of the diabetes epidemic. Nature 414 (2001) 782-787
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3
  • 2
    • 0035856980 scopus 로고    scopus 로고
    • Pathogenesis of diabetic complications
    • Bronwlee M. Pathogenesis of diabetic complications. Nature 414 (2001) 813-820
    • (2001) Nature , vol.414 , pp. 813-820
    • Bronwlee, M.1
  • 3
    • 12144251636 scopus 로고    scopus 로고
    • Postprandial hyperglycemia and diabetes complications: is time to treat?
    • Cerriello A. Postprandial hyperglycemia and diabetes complications: is time to treat?. Diabetes 54 (2005) 1-7
    • (2005) Diabetes , vol.54 , pp. 1-7
    • Cerriello, A.1
  • 4
    • 0031158830 scopus 로고    scopus 로고
    • A review of the microcirculation of adipose tissue: anatomic, metabolic and angiogenic perspectives
    • Crandall D.L., Hausman G.J., and Kral J.G. A review of the microcirculation of adipose tissue: anatomic, metabolic and angiogenic perspectives. Microcirculation 4 (1997) 211-232
    • (1997) Microcirculation , vol.4 , pp. 211-232
    • Crandall, D.L.1    Hausman, G.J.2    Kral, J.G.3
  • 5
    • 0021014504 scopus 로고
    • Impact of obesity on metabolism in men and women: importance of regional adipose tissue distribution
    • Krotkiewski M., Bjorntrop P., Sjostrom L., and Smith U. Impact of obesity on metabolism in men and women: importance of regional adipose tissue distribution. J. Clin. Invest. 72 (1983) 1150-1162
    • (1983) J. Clin. Invest. , vol.72 , pp. 1150-1162
    • Krotkiewski, M.1    Bjorntrop, P.2    Sjostrom, L.3    Smith, U.4
  • 8
    • 0034987715 scopus 로고    scopus 로고
    • The adipocyte: a model for integration of endocrine and metabolic signaling in energy metabolism regulation
    • Fruhbeck G., Gomez-Ambrosi J., Muruzabal F.J., and Burrell M.A. The adipocyte: a model for integration of endocrine and metabolic signaling in energy metabolism regulation. Am. J. Physiol. 280 (2001) E827-E847
    • (2001) Am. J. Physiol. , vol.280
    • Fruhbeck, G.1    Gomez-Ambrosi, J.2    Muruzabal, F.J.3    Burrell, M.A.4
  • 9
    • 0027459878 scopus 로고
    • Adipocyte expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance
    • Hotamisligil G.S., Shargill N.S., and Spiegelman B.M. Adipocyte expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science 259 (1993) 87-91
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 10
    • 0031762908 scopus 로고    scopus 로고
    • Omental and subcutaneous adipose tissues of obese subject release interleukin-6: depot difference and regulation by glucocorticoid
    • Fried S.K., Bunkin D.A., and Greenberg A.S. Omental and subcutaneous adipose tissues of obese subject release interleukin-6: depot difference and regulation by glucocorticoid. J. Clin. Endocrinol. Metab. 83 (1998) 847-850
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 847-850
    • Fried, S.K.1    Bunkin, D.A.2    Greenberg, A.S.3
  • 11
    • 0034470214 scopus 로고    scopus 로고
    • Interleukin-8 production in human adipose tissue: inhibitory effect of anti-diabetic compounds, the thiazolidinendione ciglitazone and the biguanide metformin
    • Bruun J.M., Pedersen S.B., and Richelsen B. Interleukin-8 production in human adipose tissue: inhibitory effect of anti-diabetic compounds, the thiazolidinendione ciglitazone and the biguanide metformin. Horm. Metab. Res. 32 (2000) 537-541
    • (2000) Horm. Metab. Res. , vol.32 , pp. 537-541
    • Bruun, J.M.1    Pedersen, S.B.2    Richelsen, B.3
  • 13
  • 15
    • 0028787490 scopus 로고
    • A novel serum protein similar to C1q, produced exclusively in adipocytes
    • Scherer P.E., Williams S., Fogliano M., Baldini G., and Lodish H.F. A novel serum protein similar to C1q, produced exclusively in adipocytes. J. Biol. Chem. 270 (1995) 26746-26749
    • (1995) J. Biol. Chem. , vol.270 , pp. 26746-26749
    • Scherer, P.E.1    Williams, S.2    Fogliano, M.3    Baldini, G.4    Lodish, H.F.5
  • 16
    • 19944433652 scopus 로고    scopus 로고
    • Visfatin: a protein secreted by visceral fat that mimics the effects of insulin
    • Fukahara A., Matsuda M., Nishizawa M., Segawa K., Tanaka M., Kishimoto K., et al. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 307 (2005) 426-430
    • (2005) Science , vol.307 , pp. 426-430
    • Fukahara, A.1    Matsuda, M.2    Nishizawa, M.3    Segawa, K.4    Tanaka, M.5    Kishimoto, K.6
  • 17
    • 11244302456 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 is produced in isolated adipocytes, associated with adiposity and reduced after weight loss in morbidly obese subjects
    • Christiansen T., Richelsen B., and Bruun M. Monocyte chemoattractant protein-1 is produced in isolated adipocytes, associated with adiposity and reduced after weight loss in morbidly obese subjects. Int. J. Obes. 29 (2005) 146-150
    • (2005) Int. J. Obes. , vol.29 , pp. 146-150
    • Christiansen, T.1    Richelsen, B.2    Bruun, M.3
  • 18
    • 22944434929 scopus 로고    scopus 로고
    • Serum retinol binding protein contributes to insulin resistance and obesity in type 2 diabetes mellitus
    • Yang Q., Graham T.E., Mody N., Preitner F., Peroni O.D., Zabolotny J.M., et al. Serum retinol binding protein contributes to insulin resistance and obesity in type 2 diabetes mellitus. Nature 436 (2005) 356-362
    • (2005) Nature , vol.436 , pp. 356-362
    • Yang, Q.1    Graham, T.E.2    Mody, N.3    Preitner, F.4    Peroni, O.D.5    Zabolotny, J.M.6
  • 20
    • 15844381594 scopus 로고    scopus 로고
    • Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity
    • Shimomura L. Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat. Med. 2 (1996) 800-803
    • (1996) Nat. Med. , vol.2 , pp. 800-803
    • Shimomura, L.1
  • 21
    • 0034504237 scopus 로고    scopus 로고
    • Subcutaneous and visceral adipose tissue; their relation to the metabolic syndrome
    • Wajchenberg B.L. Subcutaneous and visceral adipose tissue; their relation to the metabolic syndrome. Endocr. Rev. 21 (2000) 697-738
    • (2000) Endocr. Rev. , vol.21 , pp. 697-738
    • Wajchenberg, B.L.1
  • 22
    • 33847006604 scopus 로고    scopus 로고
    • Peroxisome proliferators activated receptors γ (PPARγ) and adipose tissue-understanding obesity-related changes in regulation of lipid and glucose metabolism
    • Sharma A.M., and Staels B. Peroxisome proliferators activated receptors γ (PPARγ) and adipose tissue-understanding obesity-related changes in regulation of lipid and glucose metabolism. J. Clin. Endocrinol. Metab. 92 (2007) 386-395
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 386-395
    • Sharma, A.M.1    Staels, B.2
  • 24
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu H., Barnes G.T., Yang Q., Tan G., Yang D., Chou C.J., et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112 (2003) 1821-1830
    • (2003) J. Clin. Invest. , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3    Tan, G.4    Yang, D.5    Chou, C.J.6
  • 25
    • 33745239304 scopus 로고    scopus 로고
    • Fatty acid-induced inflammation and insulin resistance in skeletal muscle and liver
    • Boden G. Fatty acid-induced inflammation and insulin resistance in skeletal muscle and liver. Curr. Diab. Rep. 6 (2006) 177-181
    • (2006) Curr. Diab. Rep. , vol.6 , pp. 177-181
    • Boden, G.1
  • 27
    • 0033849777 scopus 로고    scopus 로고
    • Obesity and insulin resistance
    • Kahn B.B., and Flier J.S. Obesity and insulin resistance. J. Clin. Invest. 106 (2000) 473-481
    • (2000) J. Clin. Invest. , vol.106 , pp. 473-481
    • Kahn, B.B.1    Flier, J.S.2
  • 29
    • 0035405847 scopus 로고    scopus 로고
    • Effect of acute changes on plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects
    • Boden G., Lebed B., Schatz M., Homko C., and Lemieux S. Effect of acute changes on plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects. Diabetes 50 (2001) 1612-1617
    • (2001) Diabetes , vol.50 , pp. 1612-1617
    • Boden, G.1    Lebed, B.2    Schatz, M.3    Homko, C.4    Lemieux, S.5
  • 30
    • 0036300538 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance in human muscle is associated with changes in diacylglicerol, protein kinase C, and IkappaB-alpha
    • Itani S.I., Ruderman N.B., Schmieder F., and Boden G. Lipid-induced insulin resistance in human muscle is associated with changes in diacylglicerol, protein kinase C, and IkappaB-alpha. Diabetes 51 (2002) 2005-2011
    • (2002) Diabetes , vol.51 , pp. 2005-2011
    • Itani, S.I.1    Ruderman, N.B.2    Schmieder, F.3    Boden, G.4
  • 31
    • 0345086474 scopus 로고    scopus 로고
    • Free fatty acid induced insulin resistance is associated with activation of protein kinase C θ and alterations in insulin signaling cascade
    • Griffin M.E., Marcucci M.J., Cline G.W., Bell K., Barucci N., Lee D., et al. Free fatty acid induced insulin resistance is associated with activation of protein kinase C θ and alterations in insulin signaling cascade. Diabetes 48 (1999) 1270-1274
    • (1999) Diabetes , vol.48 , pp. 1270-1274
    • Griffin, M.E.1    Marcucci, M.J.2    Cline, G.W.3    Bell, K.4    Barucci, N.5    Lee, D.6
  • 32
    • 0035126784 scopus 로고    scopus 로고
    • Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus. Overexpression of protein kinase Cε in skeletal muscle precedes the onset of hyperinsulinemia and hyperglycemia
    • Ikeda Y., Olsen G.S., Ziv E., Hansen L.L., Busch A.K., Hansen B.F., et al. Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus. Overexpression of protein kinase Cε in skeletal muscle precedes the onset of hyperinsulinemia and hyperglycemia. Diabetes 50 (2001) 584-592
    • (2001) Diabetes , vol.50 , pp. 584-592
    • Ikeda, Y.1    Olsen, G.S.2    Ziv, E.3    Hansen, L.L.4    Busch, A.K.5    Hansen, B.F.6
  • 33
    • 0035729343 scopus 로고    scopus 로고
    • Prevention of ventricular fibrillation during acute myocardial ischemia: control of free fatty acids
    • Oliver M.F. Prevention of ventricular fibrillation during acute myocardial ischemia: control of free fatty acids. J. Cardiovasc. Pharmacol. Ther. 6 (2001) 213-217
    • (2001) J. Cardiovasc. Pharmacol. Ther. , vol.6 , pp. 213-217
    • Oliver, M.F.1
  • 34
    • 0345275811 scopus 로고    scopus 로고
    • Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects
    • Tripathy D., Mohanty P., Dhindsa S., Syed T., Ghanim H., Aljada A., et al. Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects. Diabetes 52 (2003) 2882-2887
    • (2003) Diabetes , vol.52 , pp. 2882-2887
    • Tripathy, D.1    Mohanty, P.2    Dhindsa, S.3    Syed, T.4    Ghanim, H.5    Aljada, A.6
  • 35
    • 33745776303 scopus 로고    scopus 로고
    • Free fatty acids are independently associated with all-cause and cardiovascular mortality in subjects with coronary artery disease
    • Pilz S., Scharnagl H., Tiran B., Seelhorst U., Wellnitz B., Bohem B.O., et al. Free fatty acids are independently associated with all-cause and cardiovascular mortality in subjects with coronary artery disease. J. Clin. Endocrinol. Metab. 91 (2006) 2542-2547
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 2542-2547
    • Pilz, S.1    Scharnagl, H.2    Tiran, B.3    Seelhorst, U.4    Wellnitz, B.5    Bohem, B.O.6
  • 37
    • 0032082952 scopus 로고    scopus 로고
    • Levels of leptin in plasma of patients with type 2 diabetes
    • Kowalska I., Stra{ogonek}czkowski M., and Kinalska I. Levels of leptin in plasma of patients with type 2 diabetes. Pol. Arch. Med. Wewn. 99 (1998) 470-476
    • (1998) Pol. Arch. Med. Wewn. , vol.99 , pp. 470-476
    • Kowalska, I.1    Straczkowski, M.2    Kinalska, I.3
  • 40
    • 19344373130 scopus 로고    scopus 로고
    • Human leptin: an adipocyte hormone with weight-regulatory and endocrine function
    • Considine R.V. Human leptin: an adipocyte hormone with weight-regulatory and endocrine function. Semin. Vasc. Med. 5 (2005) 15-24
    • (2005) Semin. Vasc. Med. , vol.5 , pp. 15-24
    • Considine, R.V.1
  • 41
    • 33748970803 scopus 로고    scopus 로고
    • Leptin and atherosclerosis
    • Beltowski J. Leptin and atherosclerosis. Atherosclerosis 189 (2006) 47-60
    • (2006) Atherosclerosis , vol.189 , pp. 47-60
    • Beltowski, J.1
  • 42
    • 0034956457 scopus 로고    scopus 로고
    • Plasma leptin is independently associated with the intima media-thickness of the common carotid artery
    • Ciccone M., Vettor R., Pannacciulli N., Minenna A., Ballacicco M., Rizzon P., et al. Plasma leptin is independently associated with the intima media-thickness of the common carotid artery. Int. J. Obes. 25 (2001) 805-810
    • (2001) Int. J. Obes. , vol.25 , pp. 805-810
    • Ciccone, M.1    Vettor, R.2    Pannacciulli, N.3    Minenna, A.4    Ballacicco, M.5    Rizzon, P.6
  • 46
    • 0035930998 scopus 로고    scopus 로고
    • Suppressed gene expression of adipocyte resistin in an insulin-resistant rat model probably by elevated free fatty acids
    • Juan C.C., Au L., Fnag V., Kang S.F., Ko Y.H., Kuo S.F., et al. Suppressed gene expression of adipocyte resistin in an insulin-resistant rat model probably by elevated free fatty acids. Biochem. Biophys. Res. Commun. 289 (2001) 1328-1333
    • (2001) Biochem. Biophys. Res. Commun. , vol.289 , pp. 1328-1333
    • Juan, C.C.1    Au, L.2    Fnag, V.3    Kang, S.F.4    Ko, Y.H.5    Kuo, S.F.6
  • 47
    • 0034806403 scopus 로고    scopus 로고
    • Insulin resistance and type 2 diabetes are not related to resistin expression in human fat cells or skeletal muscle
    • Nagaev I., and Smith U. Insulin resistance and type 2 diabetes are not related to resistin expression in human fat cells or skeletal muscle. Biochem. Biophys. Res. Commun. 285 (2001) 561-564
    • (2001) Biochem. Biophys. Res. Commun. , vol.285 , pp. 561-564
    • Nagaev, I.1    Smith, U.2
  • 48
    • 0035487109 scopus 로고    scopus 로고
    • Resistin/Fizz3 expression in relation to obesity and peroxisome proliferators-activated receptor-γ action in humans
    • Savage D.B., Sewter C.P., Klenk E.S., Segal D.G., Vidal-Puig A., Considine R.V., et al. Resistin/Fizz3 expression in relation to obesity and peroxisome proliferators-activated receptor-γ action in humans. Diabetes 50 (2001) 2199-2202
    • (2001) Diabetes , vol.50 , pp. 2199-2202
    • Savage, D.B.1    Sewter, C.P.2    Klenk, E.S.3    Segal, D.G.4    Vidal-Puig, A.5    Considine, R.V.6
  • 49
    • 0036365870 scopus 로고    scopus 로고
    • Resistin gene expression in human adipocytes is not related to insulin resistance
    • Janke J., Engeli S., Gorzelniak K., Luft F.C., and Sharma A.M. Resistin gene expression in human adipocytes is not related to insulin resistance. Obes. Res. 10 (2002) 1-5
    • (2002) Obes. Res. , vol.10 , pp. 1-5
    • Janke, J.1    Engeli, S.2    Gorzelniak, K.3    Luft, F.C.4    Sharma, A.M.5
  • 51
    • 10744220840 scopus 로고    scopus 로고
    • Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus
    • Young B., Yu K., Park H.J., Lee N.S., Min S.S., Youn M.Y., et al. Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus. J. Clin. Endocrinol. Metab. 89 (2004) 150-156
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 150-156
    • Young, B.1    Yu, K.2    Park, H.J.3    Lee, N.S.4    Min, S.S.5    Youn, M.Y.6
  • 52
    • 27744545199 scopus 로고    scopus 로고
    • Resistin is not associated with insulin sensitivity or the metabolic syndrome in humans
    • Utzschneider K.M., Carr D.B., Tong J., Wallace T.M., Hull R.L., Zraika S., et al. Resistin is not associated with insulin sensitivity or the metabolic syndrome in humans. Diabetologia 48 (2005) 2330-2333
    • (2005) Diabetologia , vol.48 , pp. 2330-2333
    • Utzschneider, K.M.1    Carr, D.B.2    Tong, J.3    Wallace, T.M.4    Hull, R.L.5    Zraika, S.6
  • 53
    • 0036875933 scopus 로고    scopus 로고
    • Plasma resistin levels in patients with type 1 and type 2 diabetes mellitus and in healthy controls
    • Fehmann H., and Heyn J. Plasma resistin levels in patients with type 1 and type 2 diabetes mellitus and in healthy controls. Horm. Metab. Res. 34 (2002) 671-673
    • (2002) Horm. Metab. Res. , vol.34 , pp. 671-673
    • Fehmann, H.1    Heyn, J.2
  • 54
    • 17844392652 scopus 로고    scopus 로고
    • Resistin an adipokine with potent proinflammatory cytokine properties
    • Bokarewa M., Nagaev I., Dalhberg L., Smith U., and Tarkowski A. Resistin an adipokine with potent proinflammatory cytokine properties. J. Immunol. 174 (2005) 5789-5795
    • (2005) J. Immunol. , vol.174 , pp. 5789-5795
    • Bokarewa, M.1    Nagaev, I.2    Dalhberg, L.3    Smith, U.4    Tarkowski, A.5
  • 55
    • 0043164953 scopus 로고    scopus 로고
    • Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction
    • Verma S., Li S.H., Wang C.H., Fedark P.W., Li R.K., Weisel R.D., et al. Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction. Circulation 187 (2003) 736-740
    • (2003) Circulation , vol.187 , pp. 736-740
    • Verma, S.1    Li, S.H.2    Wang, C.H.3    Fedark, P.W.4    Li, R.K.5    Weisel, R.D.6
  • 58
    • 0043025533 scopus 로고    scopus 로고
    • Adiponectin: more than just another fat cell hormone?
    • Chandran M., Philips A.S., Ciaraldi T., and Henry R.R. Adiponectin: more than just another fat cell hormone?. Diab. Care 26 (2003) 2442-2450
    • (2003) Diab. Care , vol.26 , pp. 2442-2450
    • Chandran, M.1    Philips, A.S.2    Ciaraldi, T.3    Henry, R.R.4
  • 59
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi T., Kamon J., Ito Y., Tsuchida A., Yokomizo T., Kita S., et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423 (2003) 762-769
    • (2003) Nature , vol.423 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3    Tsuchida, A.4    Yokomizo, T.5    Kita, S.6
  • 61
    • 0035039227 scopus 로고    scopus 로고
    • Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys
    • Hotta K., Funahshi T., Bodkin N.L., Ortmeyer H.K., Arita Y., Hansen B.C., et al. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 50 (2001) 1126-1133
    • (2001) Diabetes , vol.50 , pp. 1126-1133
    • Hotta, K.1    Funahshi, T.2    Bodkin, N.L.3    Ortmeyer, H.K.4    Arita, Y.5    Hansen, B.C.6
  • 63
    • 0037031088 scopus 로고    scopus 로고
    • Adiponectin and development of type 2 diabetes in the Pima Indian population (Letter)
    • Lindsay R.S., Funahashi T., Hanson R.L., Matsuzawa Y., Tanaka S., Tataranni P.A., et al. Adiponectin and development of type 2 diabetes in the Pima Indian population (Letter). Lancet 360 (2002) 57-58
    • (2002) Lancet , vol.360 , pp. 57-58
    • Lindsay, R.S.1    Funahashi, T.2    Hanson, R.L.3    Matsuzawa, Y.4    Tanaka, S.5    Tataranni, P.A.6
  • 65
    • 0037231459 scopus 로고    scopus 로고
    • Association of hipoadiponectinemia with coronary artery disese in men
    • Osaka CAD Study Group-Coronary Artery Disease
    • Kumada M., Kihara S., Sumitsuji S., Kawamoto T., Matsumoto S., Ouchi N., and Osaka CAD Study Group-Coronary Artery Disease. Association of hipoadiponectinemia with coronary artery disese in men. Arterioscler. Thromb. Vasc. Biol. 23 (2003) 85-89
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 85-89
    • Kumada, M.1    Kihara, S.2    Sumitsuji, S.3    Kawamoto, T.4    Matsumoto, S.5    Ouchi, N.6
  • 67
    • 33644585600 scopus 로고    scopus 로고
    • Plasma adiponectin concentration and tumor necrosis factor-α system activity in lean non-diabetic offspring of type 2 diabetic subjects
    • Kowalska I., Straczkowski M., Nikołajuk A., Krukowska A., Kinalska I., and Górska M. Plasma adiponectin concentration and tumor necrosis factor-α system activity in lean non-diabetic offspring of type 2 diabetic subjects. Eur. J. Endocrinol. 154 (2006) 319-324
    • (2006) Eur. J. Endocrinol. , vol.154 , pp. 319-324
    • Kowalska, I.1    Straczkowski, M.2    Nikołajuk, A.3    Krukowska, A.4    Kinalska, I.5    Górska, M.6
  • 68
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7 (2001) 941-946
    • (2001) Nat. Med. , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Terauchi, Y.4    Kubota, N.5    Hara, K.6
  • 69
    • 0034070567 scopus 로고    scopus 로고
    • Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism
    • Hayashi T., Hirshman M.F., Fujii N., Habinowski S.A., Witters L.A., and Goodyear L.J. Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism. Diabetes 49 (2000) 527-531
    • (2000) Diabetes , vol.49 , pp. 527-531
    • Hayashi, T.1    Hirshman, M.F.2    Fujii, N.3    Habinowski, S.A.4    Witters, L.A.5    Goodyear, L.J.6
  • 70
    • 0032792665 scopus 로고    scopus 로고
    • AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes
    • Winder W.W., and Hardie D.G. AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes. Am. J. Physiol. 277 (1999) E1-E10
    • (1999) Am. J. Physiol. , vol.277
    • Winder, W.W.1    Hardie, D.G.2
  • 71
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T., Kamon J., Minokoshi Y., Ito Y., Waki H., Uchida S., et al. Adiponectin stimulates glucose utilization and fatty acid oxidation by activating AMP-activated protein kinase. Nat. Med. 8 (2002) 1288-1295
    • (2002) Nat. Med. , vol.8 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3    Ito, Y.4    Waki, H.5    Uchida, S.6
  • 72
    • 0036266897 scopus 로고    scopus 로고
    • Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans
    • Stefan N., Vozarova B., Funahashi T., Matsuzawa Y., Weyer C., Lindsay R.S., et al. Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans. Diabetes 51 (2002) 1884-1888
    • (2002) Diabetes , vol.51 , pp. 1884-1888
    • Stefan, N.1    Vozarova, B.2    Funahashi, T.3    Matsuzawa, Y.4    Weyer, C.5    Lindsay, R.S.6
  • 73
  • 74
    • 0038824160 scopus 로고    scopus 로고
    • The variation of plasma concentration of a novel, adipocyte derived protein, adiponectin, in patients with acute myocardial infarction
    • Kojima S., Funahshi T., Sakamoto T., Miyamato S., Soejima H., Hokamahi J., et al. The variation of plasma concentration of a novel, adipocyte derived protein, adiponectin, in patients with acute myocardial infarction. Heart 89 (2003) 667-668
    • (2003) Heart , vol.89 , pp. 667-668
    • Kojima, S.1    Funahshi, T.2    Sakamoto, T.3    Miyamato, S.4    Soejima, H.5    Hokamahi, J.6
  • 75
    • 0037180472 scopus 로고    scopus 로고
    • Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice
    • Okamoto Y., Kihara S., Ouchi N., Nishida M., Arita Y., Kumada M., et al. Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice. Circulation 106 (2002) 2767-2770
    • (2002) Circulation , vol.106 , pp. 2767-2770
    • Okamoto, Y.1    Kihara, S.2    Ouchi, N.3    Nishida, M.4    Arita, Y.5    Kumada, M.6
  • 76
    • 2942687834 scopus 로고    scopus 로고
    • Adiponectin: a novel adipokine linking adipocytes and vascular function
    • Goldstein B.J., and Scalia R. Adiponectin: a novel adipokine linking adipocytes and vascular function. J. Clin. Endocrinol. Metab. 89 (2004) 2563-2568
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 2563-2568
    • Goldstein, B.J.1    Scalia, R.2
  • 77
    • 0034641647 scopus 로고    scopus 로고
    • Adiponectin, an adipocyte-derived plasma protein, inhbits endothelial NF-kappaB signaling through a cAMP-dependent pathway
    • Ouchi N., Kihara S., Arita Y., Maeda K., Kuriyama H., Hotta K., et al. Adiponectin, an adipocyte-derived plasma protein, inhbits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation 102 (2000) 1296-1301
    • (2000) Circulation , vol.102 , pp. 1296-1301
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Maeda, K.4    Kuriyama, H.5    Hotta, K.6
  • 78
    • 34347369616 scopus 로고    scopus 로고
    • Plasma adiponectin and E selectin concentrations in patients with coronary heart disease and newly diagnosed disturbances of glucose metabolism
    • Kowalska I., Straczkowski M., Nikołajuk A., Kinalska I., Górska M., Prokop J., et al. Plasma adiponectin and E selectin concentrations in patients with coronary heart disease and newly diagnosed disturbances of glucose metabolism. Adv. Med. Sci. 56 (2006) 94-98
    • (2006) Adv. Med. Sci. , vol.56 , pp. 94-98
    • Kowalska, I.1    Straczkowski, M.2    Nikołajuk, A.3    Kinalska, I.4    Górska, M.5    Prokop, J.6
  • 79
    • 27144457438 scopus 로고    scopus 로고
    • Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2 dependent mechanism
    • Shibata R., Sato K., Pimentel D.R., Takemura Y., Kihara S., Ohashi K., et al. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2 dependent mechanism. Nat. Med. 11 (2005) 1096-1103
    • (2005) Nat. Med. , vol.11 , pp. 1096-1103
    • Shibata, R.1    Sato, K.2    Pimentel, D.R.3    Takemura, Y.4    Kihara, S.5    Ohashi, K.6
  • 80
    • 22744449914 scopus 로고    scopus 로고
    • Exacerbation of heart failure in adiponectin-deficient mice due to impaired regulation of AMPK and glucose metabolism
    • Liao Y., Takashima S., Maeda N., Ouchi N., Komamura K., Shimomura I., et al. Exacerbation of heart failure in adiponectin-deficient mice due to impaired regulation of AMPK and glucose metabolism. Cardiovasc. Res. 67 (2005) 705-713
    • (2005) Cardiovasc. Res. , vol.67 , pp. 705-713
    • Liao, Y.1    Takashima, S.2    Maeda, N.3    Ouchi, N.4    Komamura, K.5    Shimomura, I.6
  • 82
    • 33744972586 scopus 로고    scopus 로고
    • Cardioprotection by adiponectin
    • Ouchi N., Shibata R., and Walsh K. Cardioprotection by adiponectin. TCM 16 (2006) 141-146
    • (2006) TCM , vol.16 , pp. 141-146
    • Ouchi, N.1    Shibata, R.2    Walsh, K.3
  • 83
    • 0029900295 scopus 로고    scopus 로고
    • The tumor necrosis factor ligand and receptor families
    • Bazzoni F., and Beutler B. The tumor necrosis factor ligand and receptor families. N. Engl. J. Med. 334 (1996) 1717-1725
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1717-1725
    • Bazzoni, F.1    Beutler, B.2
  • 84
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance
    • Hotamisligil G.S., Arner P., Caro J.F., Atkinson R.L., and Spiegelman B.M. Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J. Clin. Invest. 95 (1995) 2409-2415
    • (1995) J. Clin. Invest. , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 85
    • 0030028606 scopus 로고    scopus 로고
    • The expression of TNFα by human muscle: relationship to insulin resistance
    • Saghizadeh M., Ong J.M., Garvey W.T., Henry R.R., and Kern P.A. The expression of TNFα by human muscle: relationship to insulin resistance. J. Clin. Invest. 97 (1996) 1111-1116
    • (1996) J. Clin. Invest. , vol.97 , pp. 1111-1116
    • Saghizadeh, M.1    Ong, J.M.2    Garvey, W.T.3    Henry, R.R.4    Kern, P.A.5
  • 86
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNFα and obesity-induced insulin resistance
    • Hotamisligil G.S., Peraldi P., Budavari A., Ellis R., White M.F., and Spiegelman B.M. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNFα and obesity-induced insulin resistance. Science 271 (1996) 665-668
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 87
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNFα function
    • Uysal K.T., Wiesbrock S.M., Marino M.W., and Hotamisligil G.S. Protection from obesity-induced insulin resistance in mice lacking TNFα function. Nature 389 (1997) 610-614
    • (1997) Nature , vol.389 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 88
    • 0036734285 scopus 로고    scopus 로고
    • Skeletal muscle triglycerides lowering is associated with net improvement of insulin sensitivity, TNF-alpha reduction and GLUT4 expression enhancement
    • Mingrone G., Rosa G., Di Rocco P., Manco M., Capristo E., Castagneto M., et al. Skeletal muscle triglycerides lowering is associated with net improvement of insulin sensitivity, TNF-alpha reduction and GLUT4 expression enhancement. Int. J. Obes. 26 (2002) 1165-1172
    • (2002) Int. J. Obes. , vol.26 , pp. 1165-1172
    • Mingrone, G.1    Rosa, G.2    Di Rocco, P.3    Manco, M.4    Capristo, E.5    Castagneto, M.6
  • 89
    • 3142710172 scopus 로고    scopus 로고
    • Interleukin-6 and tumor necrosis factor-alpha are not increased in patients with type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness
    • Carey A.L., Bruce C.R., Sacchetti M., Anderson M.J., Olsen D.B., Saltin B., et al. Interleukin-6 and tumor necrosis factor-alpha are not increased in patients with type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness. Diabetologia 47 (2004) 1029-1037
    • (2004) Diabetologia , vol.47 , pp. 1029-1037
    • Carey, A.L.1    Bruce, C.R.2    Sacchetti, M.3    Anderson, M.J.4    Olsen, D.B.5    Saltin, B.6
  • 90
    • 0031053823 scopus 로고    scopus 로고
    • Differential regulation of the p80 tumor necrosis factor receptor in human obesity and insulin resistance
    • Hotamisligil G.S., Arner P., Atkinson R.L., and Spiegelman B.M. Differential regulation of the p80 tumor necrosis factor receptor in human obesity and insulin resistance. Diabetes 46 (1997) 451-455
    • (1997) Diabetes , vol.46 , pp. 451-455
    • Hotamisligil, G.S.1    Arner, P.2    Atkinson, R.L.3    Spiegelman, B.M.4
  • 91
    • 0031671469 scopus 로고    scopus 로고
    • Plasma levels of the soluble fraction of tumor necrosis factor receptor 2 and insulin resistance
    • Fernandez-Real J.M., Broch M., Ricart W., Casamitjana R., Gutierrez C., Vendrell J., et al. Plasma levels of the soluble fraction of tumor necrosis factor receptor 2 and insulin resistance. Diabetes 47 (1998) 1757-1762
    • (1998) Diabetes , vol.47 , pp. 1757-1762
    • Fernandez-Real, J.M.1    Broch, M.2    Ricart, W.3    Casamitjana, R.4    Gutierrez, C.5    Vendrell, J.6
  • 92
    • 0036782871 scopus 로고    scopus 로고
    • Increased plasma-soluble tumor necrosis factor-alpha receptor 2 level in lean nondiabetic offspring of type 2 diabetic subjects
    • Straczkowski M., Kowalska I., Stepien A., Dzienis-Straczkowska S., Szelachowska M., and Kinalska I. Increased plasma-soluble tumor necrosis factor-alpha receptor 2 level in lean nondiabetic offspring of type 2 diabetic subjects. Diab. Care 25 (2002) 1824-1828
    • (2002) Diab. Care , vol.25 , pp. 1824-1828
    • Straczkowski, M.1    Kowalska, I.2    Stepien, A.3    Dzienis-Straczkowska, S.4    Szelachowska, M.5    Kinalska, I.6
  • 93
  • 94
    • 0034844883 scopus 로고    scopus 로고
    • Changes in tumor necrosis factor-alpha system and insulin sensitivity during an exercise training program in obese women with normal and impaired glucose tolerance
    • Straczkowski M., Kowalska I., Dzienis-Straczkowska S., Stepien A., Skibinska E., Szelachowska M., et al. Changes in tumor necrosis factor-alpha system and insulin sensitivity during an exercise training program in obese women with normal and impaired glucose tolerance. Eur. J. Endocrinol. 145 (2001) 273-280
    • (2001) Eur. J. Endocrinol. , vol.145 , pp. 273-280
    • Straczkowski, M.1    Kowalska, I.2    Dzienis-Straczkowska, S.3    Stepien, A.4    Skibinska, E.5    Szelachowska, M.6
  • 95
    • 7444247829 scopus 로고    scopus 로고
    • Postabsorptive and insulin-stimulated energy homeostasis and leucine turnover in offspring of type 2 diabetic patients
    • Lattuada G., Sereni L.P., Ruggieri D., Scollo A., Benedini S., Ragogna F., et al. Postabsorptive and insulin-stimulated energy homeostasis and leucine turnover in offspring of type 2 diabetic patients. Diab. Care 27 (2004) 2716-2722
    • (2004) Diab. Care , vol.27 , pp. 2716-2722
    • Lattuada, G.1    Sereni, L.P.2    Ruggieri, D.3    Scollo, A.4    Benedini, S.5    Ragogna, F.6
  • 96
    • 0038691619 scopus 로고    scopus 로고
    • Obesity, and not insulin resistance is the major determinant of serum inflammatory cardiovascular risk markers in pre-menopausal women
    • Escobar-Morreale H.F., Villuendas G., Botella-Carretero J.I., Sancho J., and San Millan J.L. Obesity, and not insulin resistance is the major determinant of serum inflammatory cardiovascular risk markers in pre-menopausal women. Diabetologia 46 (2003) 625-633
    • (2003) Diabetologia , vol.46 , pp. 625-633
    • Escobar-Morreale, H.F.1    Villuendas, G.2    Botella-Carretero, J.I.3    Sancho, J.4    San Millan, J.L.5
  • 97
    • 0029906375 scopus 로고    scopus 로고
    • Effects of an engineered human anti-TNFα antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM
    • Ofei F., Hurel S., Newkirk J., Sopwith M., and Taylor R. Effects of an engineered human anti-TNFα antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM. Diabetes 45 (1996) 881-885
    • (1996) Diabetes , vol.45 , pp. 881-885
    • Ofei, F.1    Hurel, S.2    Newkirk, J.3    Sopwith, M.4    Taylor, R.5
  • 98
    • 0034454915 scopus 로고    scopus 로고
    • No increased insulin sensitivity after a single intavenous administration of a recombinant human tumor necrosis factor receptor: Fc fusion protein in obese insulin-resistant patients
    • Paquot N., Castillo M.J., Lefebvre P.J., and Scheen A.J. No increased insulin sensitivity after a single intavenous administration of a recombinant human tumor necrosis factor receptor: Fc fusion protein in obese insulin-resistant patients. J. Clin. Endocrinol. Metab. 85 (2000) 1316-1319
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 1316-1319
    • Paquot, N.1    Castillo, M.J.2    Lefebvre, P.J.3    Scheen, A.J.4
  • 99
    • 3042725473 scopus 로고    scopus 로고
    • Lowered tumor necrosis factor receptors, but not increased insulin sensitivity, with infliximab
    • Di Rocco P., Manco M., Rosa G., Greco A.V., and Mingrone G. Lowered tumor necrosis factor receptors, but not increased insulin sensitivity, with infliximab. Obes. Res. 12 (2004) 734-739
    • (2004) Obes. Res. , vol.12 , pp. 734-739
    • Di Rocco, P.1    Manco, M.2    Rosa, G.3    Greco, A.V.4    Mingrone, G.5
  • 100
    • 0035026559 scopus 로고    scopus 로고
    • TNFα inhibits flow and insulin signaling leading to NO production in aortic endothelial cells
    • Kim F., Gallis B., and Corson M.A. TNFα inhibits flow and insulin signaling leading to NO production in aortic endothelial cells. Am. J. Physiol. 280 (2001) C1057-C1065
    • (2001) Am. J. Physiol. , vol.280
    • Kim, F.1    Gallis, B.2    Corson, M.A.3
  • 101
    • 0033761684 scopus 로고    scopus 로고
    • Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNFα
    • Youd J.M., Rattigan S., and Clark M.G. Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNFα. Diabetes 49 (2000) 1904-1909
    • (2000) Diabetes , vol.49 , pp. 1904-1909
    • Youd, J.M.1    Rattigan, S.2    Clark, M.G.3
  • 102
    • 0344731419 scopus 로고    scopus 로고
    • Tumor necrosis factor system activity is associated with insulin resistance and dyslipidemia in myotonic dystrophy
    • Fernandez-Real J.M., Molina A., Broch M., Ricart W., Gutierrez C., Casamitjana R., et al. Tumor necrosis factor system activity is associated with insulin resistance and dyslipidemia in myotonic dystrophy. Diabetes 48 (1999) 1108-1112
    • (1999) Diabetes , vol.48 , pp. 1108-1112
    • Fernandez-Real, J.M.1    Molina, A.2    Broch, M.3    Ricart, W.4    Gutierrez, C.5    Casamitjana, R.6
  • 103
    • 0029848362 scopus 로고    scopus 로고
    • Mast cells in rupture-prone areas of human coronary atheromas produce and store TNFα
    • Kaartinen M., Penttila A., and Kovanen P. Mast cells in rupture-prone areas of human coronary atheromas produce and store TNFα. Circulation 94 (1996) 2787-2792
    • (1996) Circulation , vol.94 , pp. 2787-2792
    • Kaartinen, M.1    Penttila, A.2    Kovanen, P.3
  • 104
    • 0034705240 scopus 로고    scopus 로고
    • Interleukin-1β and tumor necrosis factor-α decrease collagen synthesis and increase matrix metalloproteinase activity in vitro
    • Siwik D.A., Chang D.L.F., and Colucci W.S. Interleukin-1β and tumor necrosis factor-α decrease collagen synthesis and increase matrix metalloproteinase activity in vitro. Circ. Res. 86 (2000) 1259-1265
    • (2000) Circ. Res. , vol.86 , pp. 1259-1265
    • Siwik, D.A.1    Chang, D.L.F.2    Colucci, W.S.3
  • 106
    • 0027238016 scopus 로고
    • Tumor necrosis factor mediates the effects of endotoxin on cholesterol and triglyceride metabolism in mice
    • Memon R.A., Grunfeld C., Moser A.H., and Feingold K.R. Tumor necrosis factor mediates the effects of endotoxin on cholesterol and triglyceride metabolism in mice. Endocrinology 132 (1993) 2246-2253
    • (1993) Endocrinology , vol.132 , pp. 2246-2253
    • Memon, R.A.1    Grunfeld, C.2    Moser, A.H.3    Feingold, K.R.4
  • 107
    • 0345465925 scopus 로고    scopus 로고
    • Plasma levels of the soluble fraction of TNFα receptors 1 and 2 are independent determinants of total and LDL-cholesterol concentrations in healthy subjects
    • Fernandez-Real J.M., Gutierrez C., Ricart W., Castineira M.J., Vendrell J., and Richart C. Plasma levels of the soluble fraction of TNFα receptors 1 and 2 are independent determinants of total and LDL-cholesterol concentrations in healthy subjects. Atherosclerosis 146 (1999) 321-327
    • (1999) Atherosclerosis , vol.146 , pp. 321-327
    • Fernandez-Real, J.M.1    Gutierrez, C.2    Ricart, W.3    Castineira, M.J.4    Vendrell, J.5    Richart, C.6
  • 109
    • 0036146536 scopus 로고    scopus 로고
    • Elevated soluble intercellular adhesion molecule-1 levels in obesity: relationship to insulin resistance and tumor necrosis factor-alpha system activity
    • Straczkowski M., Lewczuk P., Dzienis-Stra{ogonek}czkowska S., Kowalska I., Stepien A., and Kinalska I. Elevated soluble intercellular adhesion molecule-1 levels in obesity: relationship to insulin resistance and tumor necrosis factor-alpha system activity. Metabolism 51 (2002) 75-78
    • (2002) Metabolism , vol.51 , pp. 75-78
    • Straczkowski, M.1    Lewczuk, P.2    Dzienis-Straczkowska, S.3    Kowalska, I.4    Stepien, A.5    Kinalska, I.6
  • 111
    • 0346098025 scopus 로고    scopus 로고
    • Identification and characterization of a novel spliced variant that encodes human soluble tumor necrosis factor receptor 2
    • Lainez B., Fernandez-Real J.M., Romero X., Esplugues E., Canete J.D., Ricart W., et al. Identification and characterization of a novel spliced variant that encodes human soluble tumor necrosis factor receptor 2. Int. Immunol. 16 (2004) 169-177
    • (2004) Int. Immunol. , vol.16 , pp. 169-177
    • Lainez, B.1    Fernandez-Real, J.M.2    Romero, X.3    Esplugues, E.4    Canete, J.D.5    Ricart, W.6
  • 112
    • 33744507713 scopus 로고    scopus 로고
    • An alternative spliced variant of circulating soluble tumor necrosis factor-alpha receptor-2 is paradoxically associated with insulin action
    • Fernandez-Real J.M., Straczkowski M., Lainez B., Chacon M.R., Kowalska I., Lopez-Bermejo A., et al. An alternative spliced variant of circulating soluble tumor necrosis factor-alpha receptor-2 is paradoxically associated with insulin action. Eur. J. Endocrinol. 154 (2006) 723-730
    • (2006) Eur. J. Endocrinol. , vol.154 , pp. 723-730
    • Fernandez-Real, J.M.1    Straczkowski, M.2    Lainez, B.3    Chacon, M.R.4    Kowalska, I.5    Lopez-Bermejo, A.6
  • 113
    • 33750003733 scopus 로고    scopus 로고
    • An alternatively spliced soluble TNFα receptor is associated with metabolic disorders: a replication study
    • Fernandez-Real J.M., Botas-Cervero P., Lainez B., Ricart W., and Delgado E. An alternatively spliced soluble TNFα receptor is associated with metabolic disorders: a replication study. Clin. Immunol. 121 (2006) 236-241
    • (2006) Clin. Immunol. , vol.121 , pp. 236-241
    • Fernandez-Real, J.M.1    Botas-Cervero, P.2    Lainez, B.3    Ricart, W.4    Delgado, E.5


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