Human adipose tissue expresses angiotensinogen and enzymes required for its conversion to angiotensin II

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 11, 1998, Pages 3925-3929

  Karlsson, Cecilia ^a   Lindell, Kajsa ^a   Ottosson, Malin ^b   Sjöström, Lars ^a   Carlsson, Björn ^a   Carlsson, Lena M S ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANGIOTENSINOGEN; CATHEPSIN D; CATHEPSIN G; DIPEPTIDYL CARBOXYPEPTIDASE; MESSENGER RNA; RENIN; RESTRICTION ENDONUCLEASE;

ADIPOCYTE; ADIPOSE TISSUE; ADULT; ARTICLE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; NORTHERN BLOTTING; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING;

EID: 0031733280     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.11.3925     Document Type: Article

References (35)

1. Reid IA, Morris BJ, Ganong WF. 1978 The renin-angiotensin system. Annu Rev Physiol. 40:377-410.
2. Phillips MI, Speakman EA, Kimura B. 1993 Levels of angiotensin and molecular biology of the tissue renin angiotensin systems. Regul Pept. 43:1-20.
3. Paul M, Wagner J, Dzau VJ. 1993 Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction. J Clin Invest. 91:2058-2064.
4. Timmermans PBMWM, Wong PC, Chiu AT, et al. 1993 Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev. 45:205-251.
5. Morgan L, Pipkin FB, Kalsheker N. 1996 Angiotensinogen: molecular biology, biochemistry and physiology. Int J Biochem Cell Biol. 28:1211-1222.
6. Négrel R, Gaillard D, Ailhaud G. 1989 Prostacyclin as a potent effector of adipose-cell differentiation. Biochem J. 257:399-405.
7. Darimont C, Vassaux G, Ailhaud G, Négrel R. 1994 Differentiation of preadipose cells: paracrine role of prostacyclin upon stimulation of adipose cells by angiotensin-II. Endocrinology. 135:2030-2036.
8. Jones BH, Standridge MK, Moustaïd N. 1997 Angiotensin II increases lipogenesis in 3T3-L1 and human adipose cells. Endocrinology. 138:1512-1519.
9. Cassis LA, Saye JA, Peach MJ. 1988 Location and regulation of rat angiotensinogen messenger RNA. Hypertension. 11:591-596.
10. Jones BH, Standridge MK, Taylor JW, Moustaïd N. 1997 Angiotensinogen gene expression in adipose tissue: analysis of obese models and hormonal and nutritional control. Am J Physiol. 273:R236-R242.
11. Crandall DL, Gordon G, Herzlinger HE, et al. 1992 Transforming growth factor alpha and atrial natriuretic peptide in white adipose tissue depots in rats. Eur J Clin Invest. 22:676-680.
12. Jonsson JR, Game PA, Head RJ, Frewin DB. 1994 The expression and localisation of the angiotensin-converting enzyme mRNA in human adipose tissue. Blood Press. 3:72-75.
13. Crandall DL, Herzlinger HE, Saunders BD, Armellino DC, Kral JG. 1994 Distribution of angiotensin II receptors in rat and human adipocytes. J Lipid Res. 35:1378-1385.
14. Genest J, Cantin M, Garcia R, et al. 1983 Extrarenal angiotensin-forming enzymes. Clin Exp Hypertens. 5:1065-1080.
15. Wolny A, Clozel JP, Rein J, et al. 1997 Functional and biochemical analysis of angiotensin II-forming pathways in the human heart. Circ Res. 80:219-227.
16. Harp JB, DiGirolamo M. 1995 Components of the renin-angiotensin system in adipose tissue: changes with maturation and adipose mass enlargement. J Gerontol A Biol Sci Med Sci. 50A:B270-B276.
17. Sjöström CD, Lissner L, Sjöström L. 1997 Relationships between changes in body composition and changes in cardiovascular risk factors: the SOS intervention study. Obes Res. 5:519-530.
18. Alonso-Galicia M, Brands MW, Zappe DH, Hall JE. 1996 Hypertension in obese Zucker rats. Role of angiotensin II and adrenergic activity. Hypertension. 28:1047-1054.
19. Smith U, Sjöström L, Bjömtorp P. 1972 Comparison of two methods for determining human adipose cell size. J Lipid Res. 13:822-824.
20. Chomczynski P, Sacchi N. 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:156-159.
21. Carlsson B, Lindell K, Gabrielsson B, et al. 1997 Obese (ob) gene defects are rare in human obesity. Obes Res. 5:30-35.
22. Carlsson B, Billig H, Rymo L, Isaksson OGP. 1990 Expression of the growth hormone-binding protein messenger RNA in the liver and extrahepatic tissues in the rat: co-expression with the growth hormone receptor. Mol Cell Endocrinol. 73:R1-R6.
23. Hobart PM, Fogliano M, O'Connor BA, Schaefer IM, Chirgwin JM. 1984 Human renin gene: structure and sequence analysis. Proc Natl Acad Sci USA. 81:5026-5030.
24. Soubrier F, Alhenc-Gelas F, Hubert C, et al. 1988 Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning. Proc Natl Acad Sci USA. 85:9386-9390.
25. Hubert C, Houot A-M, Corvol P, Soubrier F. 1991 Structure of the angiotensin I-converting enzyme gene. J Biol Chem. 266:15377-15383.
26. Redecker B, Heckendorf B, Grosch H-W, Mersmann G, Hasilik A. 1991 Molecular organization of the human cathepsin D gene. DNA Cell Biol. 10:423-431.
27. Hohn PA, Popescu NC, Hanson RD, Salvesen G, Ley TJ. 1989 Genomic organization and chromosomal localization of the human cathepsin G gene. J Biol Chem. 264:13412-13419.
28. Brown T. 1993 Analysis of DNA sequences by blotting and hybridization. In: Ausubel FM, Brent R, Kingston RE, et al., eds. Current protocols in molecular biology. Vol 1. New York: Wiley; 2.9.1-2.9.15.
29. Rubin I, Lykkegaard S, Olsen AA, Selmer J, Ballegaard M. 1988 Monoclonal antibodies against human angiotensinogen, their characterization and use in an angiotensinogen enzyme linked immunosorbent assay. J Immunoassay. 9:257-274.
30. Frederich Jr RC, Kahn BB, Peach MJ, Flier JS. 1992 Tissue-specific nutritional regulation of angiotensinogen in adipose tissue. Hypertension. 19:339-344.
31. Aubert J, Darimont C, Safonova I, Ailhaud G, Négrel R. 1997 Regulation by glucocorticoids of angiotensinogen gene expression and secretion in adipose cells. Biochem J. 328:701-706.
32. Saye JA, Cassis LA, Sturgill TW, Lynch KR, Peach MJ. 1989 Angiotensinogen gene expression in 3T3-L1 cells. Am J Physiol. 256:C448-C451.
33. Saye JA, Lynch KR, Peach MJ. 1990 Changes in angiotensinogen messenger RNA in differentiating 3T3-F442A adipocytes. Hypertension. 15:867-871.
34. Mulrow PJ. 1992 Adrenal renin: regulation and function. Front Neuroendocrinol. 13:47-60.
35. Faust PL, Kornfeld S, Chirgwin JM. 1985 Cloning and sequence analysis of cDNA for human cathepsin D. Proc Natl Acad Sci USA. 82:4910-4914.