Proposal of a guanine-based purinergic system in the mammalian central nervous system

Pharmacology and Therapeutics

Volumn 116, Issue 3, 2007, Pages 401-416

  Schmidt, André P ^a   Lara, Diogo R ^b   Souza, Diogo O ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Adenine based purines; Glutamatergic excitotoxicity; Guanine based purines; Guanosine; Neuroprotection; Purinergic neurotransmission

Indexed keywords

CAFFEINE; DIZOCILPINE; GUANINE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE; GUANOSINE TRIPHOSPHATE; METHYLXANTHINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PURINE; QUINOLINIC ACID; THEOPHYLLINE;

ASTROCYTE; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; EXCITOTOXICITY; ISCHEMIA; NERVE CELL; NEUROMODULATION; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVIEW; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ASTROCYTES; BEHAVIOR, ANIMAL; BRAIN; GLUTAMIC ACID; GUANINE NUCLEOTIDES; GUANOSINE; GUANOSINE TRIPHOSPHATE; HUMANS; NEUROPROTECTIVE AGENTS; RECEPTORS, PURINERGIC P1; RECEPTORS, PURINERGIC P2;

EID: 36148999810     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2007.07.004     Document Type: Review

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