Binding of 5′-GMP to the GluR2 AMPA receptor: Insight from targeted molecular dynamics simulations

Biochemistry

Volumn 44, Issue 44, 2005, Pages 14470-14476

  Mendieta, Jesús ^a   Gago, Federico ^b   Ramírez, Galo ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL CULTURE; COMPUTER SIMULATION; CRYSTALLOGRAPHY; MOLECULAR DYNAMICS; NEUROLOGY; NITROGEN COMPOUNDS; TOXICITY;

EXCITOTOXICITY; GUANINE NUCLEOTIDES; IONOTROPIC GLUTAMATE RECEPTORS; NEUROPROTECTIVE ACTIVITY;

PROTEINS;

6,7 DINITRO 2,3 QUINOXALINEDIONE; AMINO ACID; AMPA RECEPTOR; ARGININE; GLUTAMATE RECEPTOR 2; GUANINE NUCLEOTIDE; GUANOSINE PHOSPHATE; PHENYL GROUP; PURINE DERIVATIVE; TYROSINE; AMINO ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR STIMULATING AGENT; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 2; KAINIC ACID; QUINOXALINE DERIVATIVE;

AMINO ACID SEQUENCE; ARTICLE; AUTOMATION; CHANNEL GATING; CRYSTALLOGRAPHY; ENERGY; EXCITOTOXICITY; HYDROGEN BOND; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NEUROPROTECTION; PRIORITY JOURNAL; RECEPTOR BINDING; SIMULATION; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CHICKEN; COMPUTER PROGRAM; COMPUTER SIMULATION; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

5'-GUANYLIC ACID; ANIMALS; BINDING SITES; CHICKENS; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; KAINIC ACID; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; QUINOXALINES; RECEPTORS, AMPA; SOFTWARE;

EID: 27644511890     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051084x     Document Type: Article

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