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Volumn 29, Issue 4, 2007, Pages 337-353

B cells in glomerulonephritis: Focus on lupus nephritis

Author keywords

Antigen presentation; Autoantibodies; Autoimmunity; B cell; Glomerulonephritis; Immune complex; Lupus nephritis; Systemic lupus erythematosus; Tolerance

Indexed keywords

ANTIBODY; AUTOANTIBODY; AUTOANTIGEN;

EID: 35948956955     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-007-0092-1     Document Type: Review
Times cited : (21)

References (186)
  • 1
    • 0015935535 scopus 로고
    • Antibody structure and molecular immunology
    • Edelman GM (1973) Antibody structure and molecular immunology. Science 180:830-840
    • (1973) Science , vol.180 , pp. 830-840
    • Edelman, G.M.1
  • 2
    • 0034614896 scopus 로고    scopus 로고
    • Bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells
    • Smith KGC, Light A, O'Reilly LA, Ang SM, Strasser A, Tarlinton DM (2000) bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells. J Exp Med 191:475-484
    • (2000) J Exp Med , vol.191 , pp. 475-484
    • Smith, K.G.C.1    Light, A.2    O'Reilly, L.A.3    Ang, S.M.4    Strasser, A.5    Tarlinton, D.M.6
  • 5
    • 0035525528 scopus 로고    scopus 로고
    • From T to B and back again: Positive feedback in systemic autoimmune disease
    • Shlomchik MJ, Craft JE, Mamula MJ (2001) From T to B and back again: positive feedback in systemic autoimmune disease. Nat Rev Immunol 1:147-153
    • (2001) Nat Rev Immunol , vol.1 , pp. 147-153
    • Shlomchik, M.J.1    Craft, J.E.2    Mamula, M.J.3
  • 7
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa S (1983) Somatic generation of antibody diversity. Nature 302:575-581
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 8
    • 0027450354 scopus 로고
    • T cell-dependent B cell activation
    • Parker DC (1993) T cell-dependent B cell activation. Annu Rev Immunol 11:331-360
    • (1993) Annu Rev Immunol , vol.11 , pp. 331-360
    • Parker, D.C.1
  • 10
    • 0033831224 scopus 로고    scopus 로고
    • Dissecting affinity maturation: A model explaining selection of antibody-forming cells and memory B cells in the germinal centre
    • Tarlinton DM, Smith KGC (2000) Dissecting affinity maturation: a model explaining selection of antibody-forming cells and memory B cells in the germinal centre. Immunol Today 21:436-441
    • (2000) Immunol Today , vol.21 , pp. 436-441
    • Tarlinton, D.M.1    Smith, K.G.C.2
  • 11
    • 0030927427 scopus 로고    scopus 로고
    • Apoptosis and the B cell response to antigen
    • Tarlinton DM, Smith KG (1997) Apoptosis and the B cell response to antigen. Int Rev Immunol 15:53-71
    • (1997) Int Rev Immunol , vol.15 , pp. 53-71
    • Tarlinton, D.M.1    Smith, K.G.2
  • 13
    • 30444461383 scopus 로고    scopus 로고
    • Fcgamma receptors: Old friends and new family members
    • Nimmerjahn F, Ravetch JV (2006) Fcgamma receptors: old friends and new family members. Immunity 24:19-28
    • (2006) Immunity , vol.24 , pp. 19-28
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 14
    • 0027411971 scopus 로고
    • Complement defense mechanisms
    • Tomlinson S (1993) Complement defense mechanisms. Curr Opin Immunol 5:83-89
    • (1993) Curr Opin Immunol , vol.5 , pp. 83-89
    • Tomlinson, S.1
  • 15
    • 0031888608 scopus 로고    scopus 로고
    • Immunological ignorance of silent antigens as an explanation of tumor evasion
    • Chen L (1998) Immunological ignorance of silent antigens as an explanation of tumor evasion. Immunol Today 19:27-30
    • (1998) Immunol Today , vol.19 , pp. 27-30
    • Chen, L.1
  • 16
    • 0030818799 scopus 로고    scopus 로고
    • Balancing immunity, autoimmunity, and self-tolerance
    • Goodnow CC (1997) Balancing immunity, autoimmunity, and self-tolerance. Ann N Y Acad Sci 815:55-66
    • (1997) Ann N Y Acad Sci , vol.815 , pp. 55-66
    • Goodnow, C.C.1
  • 17
    • 0011869916 scopus 로고
    • Clonal anergy: Persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen
    • Nossal GJ, Pike BL (1980) Clonal anergy: persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen. Proc Natl Acad Sci USA 77:1602-1606
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 1602-1606
    • Nossal, G.J.1    Pike, B.L.2
  • 18
    • 0030913776 scopus 로고    scopus 로고
    • B-cell activation versus tolerance-the central role of immunoglobulin receptor engagement and T-cell help
    • Fulcher DA, Basten A (1997) B-cell activation versus tolerance-the central role of immunoglobulin receptor engagement and T-cell help. Int Rev Immunol 15:33-52
    • (1997) Int Rev Immunol , vol.15 , pp. 33-52
    • Fulcher, D.A.1    Basten, A.2
  • 19
    • 0029965138 scopus 로고    scopus 로고
    • Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
    • Goodnow CC (1996) Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. Proc Natl Acad Sci USA 93:2264-2271
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2264-2271
    • Goodnow, C.C.1
  • 20
    • 0029014435 scopus 로고
    • Antigen-induced B-cell death and elimination during germinal-centre immune responses
    • Shokat KM, Goodnow CC (1995) Antigen-induced B-cell death and elimination during germinal-centre immune responses. Nature 375:334-338
    • (1995) Nature , vol.375 , pp. 334-338
    • Shokat, K.M.1    Goodnow, C.C.2
  • 22
    • 0037342154 scopus 로고    scopus 로고
    • B cell inhibitory receptors and autoimmunity
    • Pritchard NR, Smith KG (2003) B cell inhibitory receptors and autoimmunity. Immunology 108:263-273
    • (2003) Immunology , vol.108 , pp. 263-273
    • Pritchard, N.R.1    Smith, K.G.2
  • 24
    • 0029994333 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Kotzin BL (1996) Systemic lupus erythematosus. Cell 85:303-306
    • (1996) Cell , vol.85 , pp. 303-306
    • Kotzin, B.L.1
  • 25
    • 0017337322 scopus 로고
    • Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity antinative DNA antibody with glomerulonephritis
    • Winfield JB, Faiferman I, Koffler D (1977) Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity antinative DNA antibody with glomerulonephritis. J Clin Invest 59:90-96
    • (1977) J Clin Invest , vol.59 , pp. 90-96
    • Winfield, J.B.1    Faiferman, I.2    Koffler, D.3
  • 26
    • 0021821903 scopus 로고
    • Involvement of the bcl-2 gene in human follicular lymphoma
    • Tsujimoto Y, Cossman J, Jaffe E, Croce CM (1985) Involvement of the bcl-2 gene in human follicular lymphoma. Science 228:1440-1443
    • (1985) Science , vol.228 , pp. 1440-1443
    • Tsujimoto, Y.1    Cossman, J.2    Jaffe, E.3    Croce, C.M.4
  • 27
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux DL, Cory S, Adams JM (1988) Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335:440-442
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 29
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata S (1997) Apoptosis by death factor. Cell 88:355-365
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 30
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata S, Golstein P (1995) The Fas death factor. Science 267:1449-1456
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 32
    • 0027143640 scopus 로고
    • Mature CD4+ T lymphocytes from MRL/lpr mice are resistant to receptor-mediated tolerance and apoptosis
    • Bossu P, Singer GG, Andres P, Ettinger R, Marshak-Rothstein A, Abbas AK (1993) Mature CD4+ T lymphocytes from MRL/lpr mice are resistant to receptor-mediated tolerance and apoptosis. J Immunol 151:7233-7239
    • (1993) J Immunol , vol.151 , pp. 7233-7239
    • Bossu, P.1    Singer, G.G.2    Andres, P.3    Ettinger, R.4    Marshak-Rothstein, A.5    Abbas, A.K.6
  • 33
    • 0027284016 scopus 로고
    • Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells
    • Russell JH, Wang R (1993) Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells. Eur J Immunol 23:2379-2382
    • (1993) Eur J Immunol , vol.23 , pp. 2379-2382
    • Russell, J.H.1    Wang, R.2
  • 36
    • 12344273445 scopus 로고    scopus 로고
    • The inhibitory Fcgamma receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells
    • Fukuyama H, Nimmerjahn F, Ravetch JV (2005) The inhibitory Fcgamma receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells. Nat Immunol 6:99-106
    • (2005) Nat Immunol , vol.6 , pp. 99-106
    • Fukuyama, H.1    Nimmerjahn, F.2    Ravetch, J.V.3
  • 37
    • 1842663154 scopus 로고    scopus 로고
    • Autonomous SHIP-dependent FcgammaR signaling in pre-B cells leads to inhibition of cell migration and induction of cell death
    • Brauweiler AM, Cambier JC (2004) Autonomous SHIP-dependent FcgammaR signaling in pre-B cells leads to inhibition of cell migration and induction of cell death. Immunol Lett 92:75-81
    • (2004) Immunol Lett , vol.92 , pp. 75-81
    • Brauweiler, A.M.1    Cambier, J.C.2
  • 38
    • 0037080203 scopus 로고    scopus 로고
    • The pre-B cell receptor signaling for apoptosis is negatively regulated by Fc gamma RIIB
    • Kato I, Takai T, Kudo A (2002) The pre-B cell receptor signaling for apoptosis is negatively regulated by Fc gamma RIIB. J Immunol 168:629-634
    • (2002) J Immunol , vol.168 , pp. 629-634
    • Kato, I.1    Takai, T.2    Kudo, A.3
  • 40
    • 0033509379 scopus 로고    scopus 로고
    • The spectrum of apoptotic defects and clinical manifestations, including systemic lupus erythematosus, in humans with CD95 (Fas/APO-1) mutations
    • Vaishnaw AK, Toubi E, Ohsako S, Drappa J, Buys S, Estrada J, Sitarz A, Zemel L, Chu JL, Elkon KB (1999) The spectrum of apoptotic defects and clinical manifestations, including systemic lupus erythematosus, in humans with CD95 (Fas/APO-1) mutations. Arthritis Rheum 42:1833-1842
    • (1999) Arthritis Rheum , vol.42 , pp. 1833-1842
    • Vaishnaw, A.K.1    Toubi, E.2    Ohsako, S.3    Drappa, J.4    Buys, S.5    Estrada, J.6    Sitarz, A.7    Zemel, L.8    Chu, J.L.9    Elkon, K.B.10
  • 41
    • 0032898385 scopus 로고    scopus 로고
    • Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: Relations with disease activity, antibodies to double stranded DNA, and neutropenia
    • Courtney PA, Crockard AD, Williamson K, Irvine AE, Kennedy RJ, Bell AL (1999) Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: relations with disease activity, antibodies to double stranded DNA, and neutropenia. Ann Rheum Dis 58:309-314
    • (1999) Ann Rheum Dis , vol.58 , pp. 309-314
    • Courtney, P.A.1    Crockard, A.D.2    Williamson, K.3    Irvine, A.E.4    Kennedy, R.J.5    Bell, A.L.6
  • 42
    • 0028288510 scopus 로고
    • Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
    • Casciola-Rosen LA, Anhalt G, Rosen A (1994) Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 179:1317-1330
    • (1994) J Exp Med , vol.179 , pp. 1317-1330
    • Casciola-Rosen, L.A.1    Anhalt, G.2    Rosen, A.3
  • 43
    • 0031863698 scopus 로고    scopus 로고
    • Posttranslational protein modifications, apoptosis, and the bypass of tolerance to autoantigens
    • Utz PJ, Anderson P (1998) Posttranslational protein modifications, apoptosis, and the bypass of tolerance to autoantigens. Arthritis Rheum 41:1152-1160
    • (1998) Arthritis Rheum , vol.41 , pp. 1152-1160
    • Utz, P.J.1    Anderson, P.2
  • 44
    • 0036884424 scopus 로고    scopus 로고
    • A blast from the past: Clearance of apoptotic cells regulates immune responses
    • Savill J, Dransfield I, Gregory C, Haslett C (2002) A blast from the past: clearance of apoptotic cells regulates immune responses. Nat Rev Immunol 2:965-975
    • (2002) Nat Rev Immunol , vol.2 , pp. 965-975
    • Savill, J.1    Dransfield, I.2    Gregory, C.3    Haslett, C.4
  • 46
    • 0346666716 scopus 로고    scopus 로고
    • Prothrombin binds to the surface of apoptotic, but not viable, cells and serves as a target of lupus anticoagulant autoantibodies
    • D'Agnillo P, Levine JS, Subang R, Rauch J (2003) Prothrombin binds to the surface of apoptotic, but not viable, cells and serves as a target of lupus anticoagulant autoantibodies. J Immunol 170:3408-3422
    • (2003) J Immunol , vol.170 , pp. 3408-3422
    • D'Agnillo, P.1    Levine, J.S.2    Subang, R.3    Rauch, J.4
  • 47
    • 0031825552 scopus 로고    scopus 로고
    • Systemic exposure to irradiated apoptotic cells induces autoantibody production
    • Mevorach D, Zhou JL, Song X, Elkon KB (1998) Systemic exposure to irradiated apoptotic cells induces autoantibody production. J Exp Med 188:387-392
    • (1998) J Exp Med , vol.188 , pp. 387-392
    • Mevorach, D.1    Zhou, J.L.2    Song, X.3    Elkon, K.B.4
  • 48
    • 0035889890 scopus 로고    scopus 로고
    • Accelerated Fas-mediated apoptosis of monocytes and maturing macrophages from patients with systemic lupus erythematosus: Relevance to in vitro impairment of interaction with iC3b-opsonized apoptotic cells
    • Shoshan Y, Shapira I, Toubi E, Frolkis I, Yaron M, Mevorach D (2001) Accelerated Fas-mediated apoptosis of monocytes and maturing macrophages from patients with systemic lupus erythematosus: relevance to in vitro impairment of interaction with iC3b-opsonized apoptotic cells. J Immunol 167:5963-5969
    • (2001) J Immunol , vol.167 , pp. 5963-5969
    • Shoshan, Y.1    Shapira, I.2    Toubi, E.3    Frolkis, I.4    Yaron, M.5    Mevorach, D.6
  • 49
    • 0142072318 scopus 로고    scopus 로고
    • Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus
    • Ren Y, Tang J, Mok MY, Chan AW, Wu A, Lau CS (2003) Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus. Arthritis Rheum 48:2888-2897
    • (2003) Arthritis Rheum , vol.48 , pp. 2888-2897
    • Ren, Y.1    Tang, J.2    Mok, M.Y.3    Chan, A.W.4    Wu, A.5    Lau, C.S.6
  • 50
    • 0037443775 scopus 로고    scopus 로고
    • Lupus-prone mice have an abnormal response to thioglycolate and an impaired clearance of apoptotic cells
    • Potter PK, Cortes-Hernandez J, Quartier P, Botto M, Walport MJ (2003) Lupus-prone mice have an abnormal response to thioglycolate and an impaired clearance of apoptotic cells. J Immunol 170:3223-3232
    • (2003) J Immunol , vol.170 , pp. 3223-3232
    • Potter, P.K.1    Cortes-Hernandez, J.2    Quartier, P.3    Botto, M.4    Walport, M.J.5
  • 53
    • 0029984710 scopus 로고    scopus 로고
    • Homozygous hereditary C1q deficiency and systemic lupus erythematosus. a new family and the molecular basis of C1q deficiency in three families
    • Slingsby JH, Norsworthy P, Pearce G, Vaishnaw AK, Issler H, Morley BJ, Walport MJ (1996) Homozygous hereditary C1q deficiency and systemic lupus erythematosus. A new family and the molecular basis of C1q deficiency in three families. Arthritis Rheum 39:663-670
    • (1996) Arthritis Rheum , vol.39 , pp. 663-670
    • Slingsby, J.H.1    Norsworthy, P.2    Pearce, G.3    Vaishnaw, A.K.4    Issler, H.5    Morley, B.J.6    Walport, M.J.7
  • 54
    • 0034613725 scopus 로고    scopus 로고
    • Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2
    • Chen Z, Koralov SB, Kelsoe G (2000) Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2. J Exp Med 192:1339-1352
    • (2000) J Exp Med , vol.192 , pp. 1339-1352
    • Chen, Z.1    Koralov, S.B.2    Kelsoe, G.3
  • 55
    • 0033002195 scopus 로고    scopus 로고
    • SAP-less chromatin triggers systemic lupus erythematosus
    • Paul E, Carroll MC (1999) SAP-less chromatin triggers systemic lupus erythematosus. Nat Med 5:607-608
    • (1999) Nat Med , vol.5 , pp. 607-608
    • Paul, E.1    Carroll, M.C.2
  • 58
    • 0036676975 scopus 로고    scopus 로고
    • Roles of Fc receptors in autoimmunity
    • Takai T (2002) Roles of Fc receptors in autoimmunity. Nat Rev Immunol 2:580-592
    • (2002) Nat Rev Immunol , vol.2 , pp. 580-592
    • Takai, T.1
  • 60
    • 0030031886 scopus 로고    scopus 로고
    • Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice
    • Takai T, Ono M, Hikida M, Ohmori H, Ravetch JV (1996) Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice. Nature 379:346-349
    • (1996) Nature , vol.379 , pp. 346-349
    • Takai, T.1    Ono, M.2    Hikida, M.3    Ohmori, H.4    Ravetch, J.V.5
  • 61
    • 0037446774 scopus 로고    scopus 로고
    • Essential role of Fc gamma receptors in anti-type II collagen antibody-induced arthritis
    • Kagari T, Tanaka D, Doi H, Shimozato T (2003) Essential role of Fc gamma receptors in anti-type II collagen antibody-induced arthritis. J Immunol 170:4318-4324
    • (2003) J Immunol , vol.170 , pp. 4318-4324
    • Kagari, T.1    Tanaka, D.2    Doi, H.3    Shimozato, T.4
  • 62
    • 0034610854 scopus 로고    scopus 로고
    • Fcgamma receptor IIB-deficient mice develop Goodpasture's syndrome upon immunization with type IV collagen: A novel murine model for autoimmune glomerular basement membrane disease
    • Nakamura A, Yuasa T, Ujike A, Ono M, Nukiwa T, Ravetch JV, Takai T (2000) Fcgamma receptor IIB-deficient mice develop Goodpasture's syndrome upon immunization with type IV collagen: a novel murine model for autoimmune glomerular basement membrane disease. J Exp Med 191:899-906
    • (2000) J Exp Med , vol.191 , pp. 899-906
    • Nakamura, A.1    Yuasa, T.2    Ujike, A.3    Ono, M.4    Nukiwa, T.5    Ravetch, J.V.6    Takai, T.7
  • 63
    • 0033521604 scopus 로고    scopus 로고
    • Modulation of immune complex-induced inflammation in vivo by the coordinate expression of activation and inhibitory Fc receptors
    • Clynes R, Maizes JS, Guinamard R, Ono M, Takai T, Ravetch JV (1999) Modulation of immune complex-induced inflammation in vivo by the coordinate expression of activation and inhibitory Fc receptors. J Exp Med 189:179-185
    • (1999) J Exp Med , vol.189 , pp. 179-185
    • Clynes, R.1    Maizes, J.S.2    Guinamard, R.3    Ono, M.4    Takai, T.5    Ravetch, J.V.6
  • 64
    • 0033695963 scopus 로고    scopus 로고
    • Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis
    • Bolland S, Ravetch JV (2000) Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis. Immunity 13:277-285
    • (2000) Immunity , vol.13 , pp. 277-285
    • Bolland, S.1    Ravetch, J.V.2
  • 65
    • 12844251399 scopus 로고    scopus 로고
    • Restoration of tolerance in lupus by targeted inhibitory receptor expression
    • McGaha TL, Sorrentino B, Ravetch JV (2005) Restoration of tolerance in lupus by targeted inhibitory receptor expression. Science 307:590-593
    • (2005) Science , vol.307 , pp. 590-593
    • McGaha, T.L.1    Sorrentino, B.2    Ravetch, J.V.3
  • 66
    • 0037029604 scopus 로고    scopus 로고
    • Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice
    • Bolland S, Yim YS, Tus K, Wakeland EK, Ravetch JV (2002) Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice. J Exp Med 195:1167-1174
    • (2002) J Exp Med , vol.195 , pp. 1167-1174
    • Bolland, S.1    Yim, Y.S.2    Tus, K.3    Wakeland, E.K.4    Ravetch, J.V.5
  • 67
    • 0037730377 scopus 로고    scopus 로고
    • FcgammaRIIB deficiency with Fas mutation is sufficient for the development of systemic autoimmune disease
    • Yajima K, Nakamura A, Sugahara A, Takai T (2003) FcgammaRIIB deficiency with Fas mutation is sufficient for the development of systemic autoimmune disease. Eur J Immunol 33:1020-1029
    • (2003) Eur J Immunol , vol.33 , pp. 1020-1029
    • Yajima, K.1    Nakamura, A.2    Sugahara, A.3    Takai, T.4
  • 68
    • 26444593959 scopus 로고    scopus 로고
    • FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling
    • Kono H, Kyogoku C, Suzuki T, Tsuchiya N, Honda H, Yamamoto K, Tokunaga K, Honda Z (2005) FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling. Hum Mol Genet 14:2881-2892
    • (2005) Hum Mol Genet , vol.14 , pp. 2881-2892
    • Kono, H.1    Kyogoku, C.2    Suzuki, T.3    Tsuchiya, N.4    Honda, H.5    Yamamoto, K.6    Tokunaga, K.7    Honda, Z.8
  • 70
    • 0033583479 scopus 로고    scopus 로고
    • Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
    • O'Keefe TL, Williams GT, Batista FD, Neuberger MS (1999) Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies. J Exp Med 189:1307-1313
    • (1999) J Exp Med , vol.189 , pp. 1307-1313
    • O'Keefe, T.L.1    Williams, G.T.2    Batista, F.D.3    Neuberger, M.S.4
  • 72
    • 0033180181 scopus 로고    scopus 로고
    • Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
    • Nishimura H, Nose M, Hiai H, Minato N, Honjo T (1999) Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 11:141-151
    • (1999) Immunity , vol.11 , pp. 141-151
    • Nishimura, H.1    Nose, M.2    Hiai, H.3    Minato, N.4    Honjo, T.5
  • 74
    • 0032831924 scopus 로고    scopus 로고
    • Receptor modulators of B-cell receptor signalling-CD19/CD22
    • Smith KG, Fearon DT (2000) Receptor modulators of B-cell receptor signalling-CD19/CD22. Curr Top Microbiol Immunol 245:195-212
    • (2000) Curr Top Microbiol Immunol , vol.245 , pp. 195-212
    • Smith, K.G.1    Fearon, D.T.2
  • 75
    • 0026587743 scopus 로고
    • CD19: Lowering the threshold for antigen receptor stimulation of B lymphocytes
    • Carter RH, Fearon DT (1992) CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes. Science 256:105-107
    • (1992) Science , vol.256 , pp. 105-107
    • Carter, R.H.1    Fearon, D.T.2
  • 76
    • 0030588569 scopus 로고    scopus 로고
    • CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity
    • Sato S, Ono N, Steeber DA, Pisetsky DS, Tedder TF (1996) CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity. J Immunol 157:4371-4378
    • (1996) J Immunol , vol.157 , pp. 4371-4378
    • Sato, S.1    Ono, N.2    Steeber, D.A.3    Pisetsky, D.S.4    Tedder, T.F.5
  • 77
    • 0030784484 scopus 로고    scopus 로고
    • CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes
    • Inaoki M, Sato S, Weintraub BC, Goodnow CC, Tedder TF (1997) CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. J Exp Med 186:1923-1931
    • (1997) J Exp Med , vol.186 , pp. 1923-1931
    • Inaoki, M.1    Sato, S.2    Weintraub, B.C.3    Goodnow, C.C.4    Tedder, T.F.5
  • 78
    • 0034544489 scopus 로고    scopus 로고
    • Quantitative genetic variation in CD19 expression correlates with autoimmunity
    • Sato S, Hasegawa M, Fujimoto M, Tedder TF, Takehara K (2000) Quantitative genetic variation in CD19 expression correlates with autoimmunity. J Immunol 165:6635-6643
    • (2000) J Immunol , vol.165 , pp. 6635-6643
    • Sato, S.1    Hasegawa, M.2    Fujimoto, M.3    Tedder, T.F.4    Takehara, K.5
  • 79
    • 0242708772 scopus 로고    scopus 로고
    • Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling
    • Jun JE, Goodnow CC (2003) Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling. Nat Immunol 4:1057-1064
    • (2003) Nat Immunol , vol.4 , pp. 1057-1064
    • Jun, J.E.1    Goodnow, C.C.2
  • 90
    • 0037332043 scopus 로고    scopus 로고
    • Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor
    • Seshasayee D, Valdez P, Yan M, Dixit VM, Tumas D, Grewal IS (2003) Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor. Immunity 18:279-288
    • (2003) Immunity , vol.18 , pp. 279-288
    • Seshasayee, D.1    Valdez, P.2    Yan, M.3    Dixit, V.M.4    Tumas, D.5    Grewal, I.S.6
  • 92
    • 33646198040 scopus 로고    scopus 로고
    • B cell immunobiology in disease: Evolving concepts from t he clinic
    • Martin F, Chan AC (2006) B cell immunobiology in disease: evolving concepts from the clinic. Annu Rev Immunol 24:467-496
    • (2006) Annu Rev Immunol , vol.24 , pp. 467-496
    • Martin, F.1    Chan, A.C.2
  • 93
    • 33745485521 scopus 로고    scopus 로고
    • Toll-like receptor activation in the pathogenesis of systemic lupus erythematosus
    • Means TK, Luster AD (2005) Toll-like receptor activation in the pathogenesis of systemic lupus erythematosus. Ann N Y Acad Sci 1062:242-251
    • (2005) Ann N Y Acad Sci , vol.1062 , pp. 242-251
    • Means, T.K.1    Luster, A.D.2
  • 96
    • 0019972228 scopus 로고
    • Systemic lupus erythematosus: Presence in human serum of an unusual acid-labile leukocyte interferon
    • Preble OT, Black RJ, Friedman RM, Klippel JH, Vilcek J (1982) Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon. Science 216:429-431
    • (1982) Science , vol.216 , pp. 429-431
    • Preble, O.T.1    Black, R.J.2    Friedman, R.M.3    Klippel, J.H.4    Vilcek, J.5
  • 98
    • 0025916262 scopus 로고
    • Autoimmune phenomena in patients with malignant carcinoid tumors during interferon-alpha treatment
    • Ronnblom LE, Alm GV, Oberg K (1991) Autoimmune phenomena in patients with malignant carcinoid tumors during interferon-alpha treatment. Acta Oncol 30:537-540
    • (1991) Acta Oncol , vol.30 , pp. 537-540
    • Ronnblom, L.E.1    Alm, G.V.2    Oberg, K.3
  • 99
    • 33748447541 scopus 로고    scopus 로고
    • Type I interferon in systemic lupus erythematosus and other autoimmune diseases
    • Banchereau J, Pascual V (2006) Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity 25:383-392
    • (2006) Immunity , vol.25 , pp. 383-392
    • Banchereau, J.1    Pascual, V.2
  • 101
    • 0035900481 scopus 로고    scopus 로고
    • Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus
    • Blanco P, Palucka AK, Gill M, Pascual V, Banchereau J (2001) Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science 294:1540-1543
    • (2001) Science , vol.294 , pp. 1540-1543
    • Blanco, P.1    Palucka, A.K.2    Gill, M.3    Pascual, V.4    Banchereau, J.5
  • 103
    • 2442494120 scopus 로고    scopus 로고
    • Autoimmunity through cytokine-induced dendritic cell activation
    • Banchereau J, Pascual V, Palucka AK (2004) Autoimmunity through cytokine-induced dendritic cell activation. Immunity 20:539-550
    • (2004) Immunity , vol.20 , pp. 539-550
    • Banchereau, J.1    Pascual, V.2    Palucka, A.K.3
  • 105
    • 32044460431 scopus 로고    scopus 로고
    • Cutting edge: Enhancement of antibody responses through direct stimulation of B and T cells by type I IFN
    • Le Bon A, Thompson C, Kamphuis E, Durand V, Rossmann C, Kalinke U, Tough DF (2006) Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN. J Immunol 176:2074-2078
    • (2006) J Immunol , vol.176 , pp. 2074-2078
    • Le Bon, A.1    Thompson, C.2    Kamphuis, E.3    Durand, V.4    Rossmann, C.5    Kalinke, U.6    Tough, D.F.7
  • 108
    • 0024506642 scopus 로고
    • Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney
    • Raz E, Brezis M, Rosenmann E, Eilat D (1989) Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney. J Immunol 142:3076-3082
    • (1989) J Immunol , vol.142 , pp. 3076-3082
    • Raz, E.1    Brezis, M.2    Rosenmann, E.3    Eilat, D.4
  • 110
    • 0018417746 scopus 로고
    • Serologically active clinically quiescent systemic lupus erythematosus: A discordance between clinical and serologic features
    • Gladman DD, Urowitz MB, Keystone EC (1979) Serologically active clinically quiescent systemic lupus erythematosus: a discordance between clinical and serologic features. Am J Med 66:210-215
    • (1979) Am J Med , vol.66 , pp. 210-215
    • Gladman, D.D.1    Urowitz, M.B.2    Keystone, E.C.3
  • 111
    • 0029871831 scopus 로고    scopus 로고
    • Emerging concepts regarding B cells and autoantibodies in murine lupus nephritis. B cells have multiple roles; All autoantibodies are not equal
    • Madaio MP, Shlomchik MJ (1996) Emerging concepts regarding B cells and autoantibodies in murine lupus nephritis. B cells have multiple roles; all autoantibodies are not equal. J Am Soc Nephrol 7:387-396
    • (1996) J Am Soc Nephrol , vol.7 , pp. 387-396
    • Madaio, M.P.1    Shlomchik, M.J.2
  • 112
    • 0037340440 scopus 로고    scopus 로고
    • Lupus autoantibodies 101: One size does not fit all; However, specificity influences pathogenicity
    • Madaio MP (2003) Lupus autoantibodies 101: one size does not fit all; however, specificity influences pathogenicity. Clin Exp Immunol 131:396-397
    • (2003) Clin Exp Immunol , vol.131 , pp. 396-397
    • Madaio, M.P.1
  • 113
    • 0019492952 scopus 로고
    • Identification of retroviral gp70 and anti-gp70 antibodies involved in circulating immune complexes in NZB X NZW mice
    • Izui S, Elder JH, McConahey PJ, Dixon FJ (1981) Identification of retroviral gp70 and anti-gp70 antibodies involved in circulating immune complexes in NZB X NZW mice. J Exp Med 153:1151-1160
    • (1981) J Exp Med , vol.153 , pp. 1151-1160
    • Izui, S.1    Elder, J.H.2    McConahey, P.J.3    Dixon, F.J.4
  • 114
    • 0035424165 scopus 로고    scopus 로고
    • Autoantigen glycoprotein 70 expression is regulated by a single locus, which acts as a checkpoint for pathogenic anti-glycoprotein 70 autoantibody production and hence for the corresponding development of severe nephritis, in lupus-prone PXSB mice
    • Haywood ME, Vyse TJ, McDermott A, Thompson EM, Ida A, Walport MJ, Izui S, Morley BJ (2001) Autoantigen glycoprotein 70 expression is regulated by a single locus, which acts as a checkpoint for pathogenic anti-glycoprotein 70 autoantibody production and hence for the corresponding development of severe nephritis, in lupus-prone PXSB mice. J Immunol 167:1728-1733
    • (2001) J Immunol , vol.167 , pp. 1728-1733
    • Haywood, M.E.1    Vyse, T.J.2    McDermott, A.3    Thompson, E.M.4    Ida, A.5    Walport, M.J.6    Izui, S.7    Morley, B.J.8
  • 115
    • 0028952442 scopus 로고
    • Glomerular binding activity in MRL lpr serum consists of antibodies that bind to a DNA/histone/type IV collagen complex
    • Bernstein KA, Valerio RD, Lefkowith JB (1995) Glomerular binding activity in MRL lpr serum consists of antibodies that bind to a DNA/histone/type IV collagen complex. J Immunol 154:2424-2433
    • (1995) J Immunol , vol.154 , pp. 2424-2433
    • Bernstein, K.A.1    Valerio, R.D.2    Lefkowith, J.B.3
  • 117
    • 0032813046 scopus 로고    scopus 로고
    • Role of nucleosomes for induction and glomerular binding of autoantibodies in lupus nephritis
    • Berden JH, Licht R, van Bruggen MC, Tax WJ (1999) Role of nucleosomes for induction and glomerular binding of autoantibodies in lupus nephritis. Curr Opin Nephrol Hypertens 8:299-306
    • (1999) Curr Opin Nephrol Hypertens , vol.8 , pp. 299-306
    • Berden, J.H.1    Licht, R.2    Van Bruggen, M.C.3    Tax, W.J.4
  • 118
    • 0038011861 scopus 로고    scopus 로고
    • The role of antibodies and B cells in the pathogenesis of lupus nephritis
    • Shlomchik MJ, Madaio MP (2003) The role of antibodies and B cells in the pathogenesis of lupus nephritis. Springer Semin Immunopathol 24:363-375
    • (2003) Springer Semin Immunopathol , vol.24 , pp. 363-375
    • Shlomchik, M.J.1    Madaio, M.P.2
  • 119
    • 0018875296 scopus 로고
    • Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte
    • Fearon DT (1980) Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte. J Exp Med 152:20-30
    • (1980) J Exp Med , vol.152 , pp. 20-30
    • Fearon, D.T.1
  • 120
    • 0020712533 scopus 로고
    • NIH Conference: Immunoglobulin G Fc receptor-mediated clearance in autoimmune diseases
    • Frank MM, Lawley TJ, Hamburger MI, Brown EJ (1983) NIH Conference: Immunoglobulin G Fc receptor-mediated clearance in autoimmune diseases. Ann Intern Med 98:206-218
    • (1983) Ann Intern Med , vol.98 , pp. 206-218
    • Frank, M.M.1    Lawley, T.J.2    Hamburger, M.I.3    Brown, E.J.4
  • 121
    • 0020693429 scopus 로고
    • Endocytosis by the mononuclear phagocyte system and autoimmune disease
    • Kimberly RP, Ralph P (1983) Endocytosis by the mononuclear phagocyte system and autoimmune disease. Am J Med 74:481-493
    • (1983) Am J Med , vol.74 , pp. 481-493
    • Kimberly, R.P.1    Ralph, P.2
  • 122
    • 0018776991 scopus 로고
    • Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus
    • Frank MM, Hamburger MI, Lawley TJ, Kimberly RP, Plotz PH (1979) Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus. N Engl J Med 300:518-523
    • (1979) N Engl J Med , vol.300 , pp. 518-523
    • Frank, M.M.1    Hamburger, M.I.2    Lawley, T.J.3    Kimberly, R.P.4    Plotz, P.H.5
  • 123
    • 0020042886 scopus 로고
    • A serial study of splenic reticuloendothelial system Fc receptor functional activity in systemic lupus erythematosus
    • Hamburger MI, Lawley TJ, Kimberly RP, Plotz PH, Frank MM (1982) A serial study of splenic reticuloendothelial system Fc receptor functional activity in systemic lupus erythematosus. Arthritis Rheum 25:48-54
    • (1982) Arthritis Rheum , vol.25 , pp. 48-54
    • Hamburger, M.I.1    Lawley, T.J.2    Kimberly, R.P.3    Plotz, P.H.4    Frank, M.M.5
  • 124
    • 0026458282 scopus 로고
    • Immune complex processing in patients with systemic lupus erythematosus. in vivo imaging and clearance studies
    • Davies KA, Peters AM, Beynon HL, Walport MJ (1992) Immune complex processing in patients with systemic lupus erythematosus. In vivo imaging and clearance studies. J Clin Invest 90:2075-2083
    • (1992) J Clin Invest , vol.90 , pp. 2075-2083
    • Davies, K.A.1    Peters, A.M.2    Beynon, H.L.3    Walport, M.J.4
  • 125
    • 0036225947 scopus 로고    scopus 로고
    • Defective Fc-dependent processing of immune complexes in patients with systemic lupus erythematosus
    • Davies KA, Robson MG, Peters AM, Norsworthy P, Nash JT, Walport MJ (2002) Defective Fc-dependent processing of immune complexes in patients with systemic lupus erythematosus. Arthritis Rheum 46:1028-1038
    • (2002) Arthritis Rheum , vol.46 , pp. 1028-1038
    • Davies, K.A.1    Robson, M.G.2    Peters, A.M.3    Norsworthy, P.4    Nash, J.T.5    Walport, M.J.6
  • 126
    • 0029560477 scopus 로고
    • Genetics of systemic lupus erythematosus
    • Schur PH (1995) Genetics of systemic lupus erythematosus. Lupus 4:425-437
    • (1995) Lupus , vol.4 , pp. 425-437
    • Schur, P.H.1
  • 127
    • 0031921084 scopus 로고    scopus 로고
    • The role of complement and complement receptors in induction and regulation of immunity
    • Carroll MC (1998) The role of complement and complement receptors in induction and regulation of immunity. Annu Rev Immunol 16:545-568
    • (1998) Annu Rev Immunol , vol.16 , pp. 545-568
    • Carroll, M.C.1
  • 129
    • 10944226539 scopus 로고    scopus 로고
    • Restoration of C1q levels by bone marrow transplantation attenuates autoimmune disease associated with C1q deficiency in mice
    • Cortes-Hernandez J, Fossati-Jimack L, Petry F, Loos M, Izui S, Walport MJ, Cook HT, Botto M (2004) Restoration of C1q levels by bone marrow transplantation attenuates autoimmune disease associated with C1q deficiency in mice. Eur J Immunol 34:3713-3722
    • (2004) Eur J Immunol , vol.34 , pp. 3713-3722
    • Cortes-Hernandez, J.1    Fossati-Jimack, L.2    Petry, F.3    Loos, M.4    Izui, S.5    Walport, M.J.6    Cook, H.T.7    Botto, M.8
  • 130
    • 0027204803 scopus 로고
    • Human IgG Fc receptor heterogeneity: Molecular aspects and clinical implications
    • van de Winkel JG, Capel PJ (1993) Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications. Immunol Today 14:215-221
    • (1993) Immunol Today , vol.14 , pp. 215-221
    • Van De Winkel, J.G.1    Capel, P.J.2
  • 131
    • 0026492077 scopus 로고
    • On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets. Analysis of a functional polymorphism to human IgG2
    • Parren PW, Warmerdam PA, Boeije LC, Arts J, Westerdaal NA, Vlug A, Capel PJ, Aarden LA, van de Winkel JG (1992) On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets. Analysis of a functional polymorphism to human IgG2. J Clin Invest 90:1537-1546
    • (1992) J Clin Invest , vol.90 , pp. 1537-1546
    • Parren, P.W.1    Warmerdam, P.A.2    Boeije, L.C.3    Arts, J.4    Westerdaal, N.A.5    Vlug, A.6    Capel, P.J.7    Aarden, L.A.8    Van De Winkel, J.G.9
  • 132
    • 0026766436 scopus 로고
    • Allelic polymorphisms of human Fc gamma receptor IIA and Fc gamma receptor IIIB. Independent mechanisms for differences in human phagocyte function
    • Salmon JE, Edberg JC, Brogle NL, Kimberly RP (1992) Allelic polymorphisms of human Fc gamma receptor IIA and Fc gamma receptor IIIB. Independent mechanisms for differences in human phagocyte function. J Clin Invest 89:1274-1281
    • (1992) J Clin Invest , vol.89 , pp. 1274-1281
    • Salmon, J.E.1    Edberg, J.C.2    Brogle, N.L.3    Kimberly, R.P.4
  • 133
    • 0032779054 scopus 로고    scopus 로고
    • Variant genotypes of the low-affinity Fcgamma receptors in two control populations and a review of low-affinity Fcgamma receptor polymorphisms in control and disease populations
    • Lehrnbecher T, Foster CB, Zhu S, Leitman SF, Goldin LR, Huppi K, Chanock SJ (1999) Variant genotypes of the low-affinity Fcgamma receptors in two control populations and a review of low-affinity Fcgamma receptor polymorphisms in control and disease populations. Blood 94:4220-4232
    • (1999) Blood , vol.94 , pp. 4220-4232
    • Lehrnbecher, T.1    Foster, C.B.2    Zhu, S.3    Leitman, S.F.4    Goldin, L.R.5    Huppi, K.6    Chanock, S.J.7
  • 135
    • 0033238172 scopus 로고    scopus 로고
    • Overrepresentation of the Fcgamma receptor type IIA R131/R131 genotype in Caucasoid systemic lupus erythematosus patients with autoantibodies to C1q and glomerulonephritis
    • Norsworthy P, Theodoridis E, Botto M, Athanassiou P, Beynon H, Gordon C, Isenberg D, Walport MJ, Davies KA (1999) Overrepresentation of the Fcgamma receptor type IIA R131/R131 genotype in Caucasoid systemic lupus erythematosus patients with autoantibodies to C1q and glomerulonephritis. Arthritis Rheum 42:1828-1832
    • (1999) Arthritis Rheum , vol.42 , pp. 1828-1832
    • Norsworthy, P.1    Theodoridis, E.2    Botto, M.3    Athanassiou, P.4    Beynon, H.5    Gordon, C.6    Isenberg, D.7    Walport, M.J.8    Davies, K.A.9
  • 137
    • 0034958157 scopus 로고    scopus 로고
    • Fc gamma RIII mediates neutrophil recruitment to immune complexes. a mechanism for neutrophil accumulation in immune-mediated inflammation
    • Coxon A, Cullere X, Knight S, Sethi S, Wakelin MW, Stavrakis G, Luscinskas FW, Mayadas TN (2001) Fc gamma RIII mediates neutrophil recruitment to immune complexes. a mechanism for neutrophil accumulation in immune-mediated inflammation. Immunity 14:693-704
    • (2001) Immunity , vol.14 , pp. 693-704
    • Coxon, A.1    Cullere, X.2    Knight, S.3    Sethi, S.4    Wakelin, M.W.5    Stavrakis, G.6    Luscinskas, F.W.7    Mayadas, T.N.8
  • 138
    • 0028990142 scopus 로고
    • Fc gamma receptor IIIb enhances Fc gamma receptor IIa function in an oxidant-dependent and allele-sensitive manner
    • Salmon JE, Millard SS, Brogle NL, Kimberly RP (1995) Fc gamma receptor IIIb enhances Fc gamma receptor IIa function in an oxidant-dependent and allele-sensitive manner. J Clin Invest 95:2877-2885
    • (1995) J Clin Invest , vol.95 , pp. 2877-2885
    • Salmon, J.E.1    Millard, S.S.2    Brogle, N.L.3    Kimberly, R.P.4
  • 143
    • 0032512855 scopus 로고    scopus 로고
    • Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis
    • Clynes R, Dumitru C, Ravetch JV (1998) Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis. Science 279:1052-1054
    • (1998) Science , vol.279 , pp. 1052-1054
    • Clynes, R.1    Dumitru, C.2    Ravetch, J.V.3
  • 144
    • 0035810399 scopus 로고    scopus 로고
    • Complement. First of two parts
    • Walport MJ (2001) Complement. First of two parts. N Engl J Med 344:1058-1066
    • (2001) N Engl J Med , vol.344 , pp. 1058-1066
    • Walport, M.J.1
  • 145
    • 17644387784 scopus 로고    scopus 로고
    • MHC class I expression regulates susceptibility to spontaneous autoimmune disease in (NZBxNZW)F1 mice
    • Mozes E, Lovchik J, Zinger H, Singer DS (2005) MHC class I expression regulates susceptibility to spontaneous autoimmune disease in (NZBxNZW)F1 mice. Lupus 14:308-314
    • (2005) Lupus , vol.14 , pp. 308-314
    • Mozes, E.1    Lovchik, J.2    Zinger, H.3    Singer, D.S.4
  • 146
    • 22144457050 scopus 로고    scopus 로고
    • T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells
    • Zhu J, Liu X, Xie C, Yan M, Yu Y, Sobel ES, Wakeland EK, Mohan C (2005) T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells. J Clin Invest 115:1869-1878
    • (2005) J Clin Invest , vol.115 , pp. 1869-1878
    • Zhu, J.1    Liu, X.2    Xie, C.3    Yan, M.4    Yu, Y.5    Sobel, E.S.6    Wakeland, E.K.7    Mohan, C.8
  • 147
    • 33749622448 scopus 로고    scopus 로고
    • Monocyte-derived dendritic cells over-express CD86 in patients with systemic lupus erythematosus
    • Decker P, Kotter I, Klein R, Berner B, Rammensee HG (2006) Monocyte-derived dendritic cells over-express CD86 in patients with systemic lupus erythematosus. Rheumatology (Oxford) 45:1087-1095
    • (2006) Rheumatology (Oxford) , vol.45 , pp. 1087-1095
    • Decker, P.1    Kotter, I.2    Klein, R.3    Berner, B.4    Rammensee, H.G.5
  • 148
    • 0242579484 scopus 로고    scopus 로고
    • A novel polymorphism in the Fcgamma receptor IIB (CD32B) transmembrane region alters receptor signaling
    • Li X, Wu J, Carter RH, Edberg JC, Su K, Cooper GS, Kimberly RP (2003) A novel polymorphism in the Fcgamma receptor IIB (CD32B) transmembrane region alters receptor signaling. Arthritis Rheum 48:3242-3252
    • (2003) Arthritis Rheum , vol.48 , pp. 3242-3252
    • Li, X.1    Wu, J.2    Carter, R.H.3    Edberg, J.C.4    Su, K.5    Cooper, G.S.6    Kimberly, R.P.7
  • 150
    • 1642521645 scopus 로고    scopus 로고
    • Association of Fcgamma receptor IIb polymorphism with susceptibility to systemic lupus erythematosus in Chinese: A common susceptibility gene in the Asian populations
    • Chu ZT, Tsuchiya N, Kyogoku C, Ohashi J, Qian YP, Xu SB, Mao CZ, Chu JY, Tokunaga K (2004) Association of Fcgamma receptor IIb polymorphism with susceptibility to systemic lupus erythematosus in Chinese: a common susceptibility gene in the Asian populations. Tissue Antigens 63:21-27
    • (2004) Tissue Antigens , vol.63 , pp. 21-27
    • Chu, Z.T.1    Tsuchiya, N.2    Kyogoku, C.3    Ohashi, J.4    Qian, Y.P.5    Xu, S.B.6    Mao, C.Z.7    Chu, J.Y.8    Tokunaga, K.9
  • 153
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
    • Chan OT, Hannum LG, Haberman AM, Madaio MP, Shlomchik MJ (1999) A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J Exp Med 189:1639-1648
    • (1999) J Exp Med , vol.189 , pp. 1639-1648
    • Chan, O.T.1    Hannum, L.G.2    Haberman, A.M.3    Madaio, M.P.4    Shlomchik, M.J.5
  • 155
    • 33749155438 scopus 로고    scopus 로고
    • B cells drive early T cell autoimmunity in vivo prior to dendritic cell-mediated autoantigen presentation
    • Yan J, Harvey BP, Gee RJ, Shlomchik MJ, Mamula MJ (2006) B cells drive early T cell autoimmunity in vivo prior to dendritic cell-mediated autoantigen presentation. J Immunol 177:4481-4487
    • (2006) J Immunol , vol.177 , pp. 4481-4487
    • Yan, J.1    Harvey, B.P.2    Gee, R.J.3    Shlomchik, M.J.4    Mamula, M.J.5
  • 158
    • 0032030667 scopus 로고    scopus 로고
    • Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: Preservation of kidney function
    • Kalled SL, Cutler AH, Datta SK, Thomas DW (1998) Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: preservation of kidney function. J Immunol 160:2158-2165
    • (1998) J Immunol , vol.160 , pp. 2158-2165
    • Kalled, S.L.1    Cutler, A.H.2    Datta, S.K.3    Thomas, D.W.4
  • 159
    • 0345824714 scopus 로고    scopus 로고
    • Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions
    • Grammer AC, Slota R, Fischer R, Gur H, Girschick H, Yarboro C, Illei GG, Lipsky PE (2003) Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions. J Clin Invest 112:1506-1520
    • (2003) J Clin Invest , vol.112 , pp. 1506-1520
    • Grammer, A.C.1    Slota, R.2    Fischer, R.3    Gur, H.4    Girschick, H.5    Yarboro, C.6    Illei, G.G.7    Lipsky, P.E.8
  • 160
    • 2942711587 scopus 로고    scopus 로고
    • Lessons learned from anti-CD40L treatment in systemic lupus erythematosus patients
    • Sidiropoulos PI, Boumpas DT (2004) Lessons learned from anti-CD40L treatment in systemic lupus erythematosus patients. Lupus 13:391-397
    • (2004) Lupus , vol.13 , pp. 391-397
    • Sidiropoulos, P.I.1    Boumpas, D.T.2
  • 161
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S (2005) Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 6:345-352
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 164
    • 0037450740 scopus 로고    scopus 로고
    • Prevention of arthritis by interleukin 10-producing B cells
    • Mauri C, Gray D, Mushtaq N, Londei M (2003) Prevention of arthritis by interleukin 10-producing B cells. J Exp Med 197:489-501
    • (2003) J Exp Med , vol.197 , pp. 489-501
    • Mauri, C.1    Gray, D.2    Mushtaq, N.3    Londei, M.4
  • 166
    • 0036197923 scopus 로고    scopus 로고
    • Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
    • Mizoguchi A, Mizoguchi E, Takedatsu H, Blumberg RS, Bhan AK (2002) Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity 16:219-230
    • (2002) Immunity , vol.16 , pp. 219-230
    • Mizoguchi, A.1    Mizoguchi, E.2    Takedatsu, H.3    Blumberg, R.S.4    Bhan, A.K.5
  • 167
    • 15244349648 scopus 로고    scopus 로고
    • TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production
    • Lenert P, Brummel R, Field EH, Ashman RF (2005) TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production. J Clin Immunol 25:29-40
    • (2005) J Clin Immunol , vol.25 , pp. 29-40
    • Lenert, P.1    Brummel, R.2    Field, E.H.3    Ashman, R.F.4
  • 168
    • 13544254614 scopus 로고    scopus 로고
    • Activation of marginal zone B cells from lupus mice with type A(D)
    • Brummel R, Lenert P (2005) Activation of marginal zone B cells from lupus mice with type A(D) CpG-oligodeoxynucleotides. J Immunol 174:2429-2434
    • (2005) J Immunol , vol.174 , pp. 2429-2434
    • Brummel, R.1    Lenert, P.2
  • 170
    • 34250850124 scopus 로고    scopus 로고
    • The human immunomodulatory CD25+ B cell population belongs to the memory B cell pool
    • Amu S, Tarkowski A, Dorner T, Bokarewa M, Brisslert M (2007) The human immunomodulatory CD25+ B cell population belongs to the memory B cell pool. Scand J Immunol 66:77-86
    • (2007) Scand J Immunol , vol.66 , pp. 77-86
    • Amu, S.1    Tarkowski, A.2    Dorner, T.3    Bokarewa, M.4    Brisslert, M.5
  • 171
    • 0029867033 scopus 로고    scopus 로고
    • Disease severity in patients with systemic lupus erythematosus correlates with an increased ratio of interleukin-10: Interferon-gamma-secreting cells in the peripheral blood
    • Hagiwara E, Gourley MF, Lee S, Klinman DK (1996) Disease severity in patients with systemic lupus erythematosus correlates with an increased ratio of interleukin-10: interferon-gamma-secreting cells in the peripheral blood. Arthritis Rheum 39:379-385
    • (1996) Arthritis Rheum , vol.39 , pp. 379-385
    • Hagiwara, E.1    Gourley, M.F.2    Lee, S.3    Klinman, D.K.4
  • 172
    • 0031977667 scopus 로고    scopus 로고
    • Decreased production of interleukin-12 and other Th1-type cytokines in patients with recent-onset systemic lupus erythematosus
    • Horwitz DA, Gray JD, Behrendsen SC, Kubin M, Rengaraju M, Ohtsuka K, Trinchieri G (1998) Decreased production of interleukin-12 and other Th1-type cytokines in patients with recent-onset systemic lupus erythematosus. Arthritis Rheum 41:838-844
    • (1998) Arthritis Rheum , vol.41 , pp. 838-844
    • Horwitz, D.A.1    Gray, J.D.2    Behrendsen, S.C.3    Kubin, M.4    Rengaraju, M.5    Ohtsuka, K.6    Trinchieri, G.7
  • 173
    • 0025673971 scopus 로고
    • Interleukin 10, a novel B cell stimulatory factor: Unresponsiveness of X chromosome-linked immunodeficiency B cells
    • Go NF, Castle BE, Barrett R, Kastelein R, Dang W, Mosmann TR, Moore KW, Howard M (1990) Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells. J Exp Med 172:1625-1631
    • (1990) J Exp Med , vol.172 , pp. 1625-1631
    • Go, N.F.1    Castle, B.E.2    Barrett, R.3    Kastelein, R.4    Dang, W.5    Mosmann, T.R.6    Moore, K.W.7    Howard, M.8
  • 176
    • 0037124367 scopus 로고    scopus 로고
    • Inducing tumor immunity through the selective engagement of activating Fcgamma receptors on dendritic cells
    • Kalergis AM, Ravetch JV (2002) Inducing tumor immunity through the selective engagement of activating Fcgamma receptors on dendritic cells. J Exp Med 195:1653-1659
    • (2002) J Exp Med , vol.195 , pp. 1653-1659
    • Kalergis, A.M.1    Ravetch, J.V.2
  • 178
    • 0037399064 scopus 로고    scopus 로고
    • Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease
    • Bruhns P, Samuelsson A, Pollard JW, Ravetch JV (2003) Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. Immunity 18:573-581
    • (2003) Immunity , vol.18 , pp. 573-581
    • Bruhns, P.1    Samuelsson, A.2    Pollard, J.W.3    Ravetch, J.V.4
  • 179
    • 0036208217 scopus 로고    scopus 로고
    • The rediscovery of the lymphatic system: Old and new insights into the development and biological function of the lymphatic vasculature
    • Oliver G, Detmar M (2002) The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature. Genes Dev 16:773-783
    • (2002) Genes Dev , vol.16 , pp. 773-783
    • Oliver, G.1    Detmar, M.2
  • 182
    • 33344475672 scopus 로고    scopus 로고
    • Lymphoid neogenesis in chronic inflammatory diseases
    • Aloisi F, Pujol-Borrell R (2006) Lymphoid neogenesis in chronic inflammatory diseases. Nat Rev Immunol 6:205-217
    • (2006) Nat Rev Immunol , vol.6 , pp. 205-217
    • Aloisi, F.1    Pujol-Borrell, R.2
  • 183
    • 32644462769 scopus 로고    scopus 로고
    • Antigen presentation by dendritic cells in renal lymph nodes is linked to systemic and local injury to the kidney
    • Dong X, Swaminathan S, Bachman LA, Croatt AJ, Nath KA, Griffin MD (2005) Antigen presentation by dendritic cells in renal lymph nodes is linked to systemic and local injury to the kidney. Kidney Int 68:1096-1108
    • (2005) Kidney Int , vol.68 , pp. 1096-1108
    • Dong, X.1    Swaminathan, S.2    Bachman, L.A.3    Croatt, A.J.4    Nath, K.A.5    Griffin, M.D.6
  • 185
    • 28544449032 scopus 로고    scopus 로고
    • B-cell depletion in the treatment of patients with systemic lupus erythematosus: A longitudinal analysis of 24 patients
    • Leandro MJ, Cambridge G, Edwards JC, Ehrenstein MR, Isenberg DA (2005) B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients. Rheumatology (Oxford) 44:1542-1545
    • (2005) Rheumatology (Oxford) , vol.44 , pp. 1542-1545
    • Leandro, M.J.1    Cambridge, G.2    Edwards, J.C.3    Ehrenstein, M.R.4    Isenberg, D.A.5
  • 186
    • 33749331884 scopus 로고    scopus 로고
    • Long-term comparison of rituximab treatment for refractory systemic lupus erythematosus and vasculitis: Remission, relapse, and re-treatment
    • Smith KG, Jones RB, Burns SM, Jayne DR (2006) Long-term comparison of rituximab treatment for refractory systemic lupus erythematosus and vasculitis: Remission, relapse, and re-treatment. Arthritis Rheum 54:2970-2982
    • (2006) Arthritis Rheum , vol.54 , pp. 2970-2982
    • Smith, K.G.1    Jones, R.B.2    Burns, S.M.3    Jayne, D.R.4


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