메뉴 건너뛰기




Volumn 225, Issue 1, 2007, Pages 1-27

New and evolving concepts in the neurotoxicology of lead

Author keywords

Alzheimer's disease; Amyloid protein; Chaperones; Conformational disease; Hypothalamic pituitary adrenal axis; Lead; Long term potentiation; Stress; Synaptic plasticity

Indexed keywords

GLUCOCORTICOID; GLUCOSE REGULATED PROTEIN 78; GLUTAMIC ACID; INTERLEUKIN 6; LEAD; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 35649023261     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.08.001     Document Type: Review
Times cited : (351)

References (238)
  • 1
    • 0033401842 scopus 로고    scopus 로고
    • Socioeconomic status and health: what we know and what we don't
    • Adler N.E., and Ostrove J.M. Socioeconomic status and health: what we know and what we don't. Ann. N.Y. Acad. Sci. 896 (1999) 3-15
    • (1999) Ann. N.Y. Acad. Sci. , vol.896 , pp. 3-15
    • Adler, N.E.1    Ostrove, J.M.2
  • 2
    • 0036518041 scopus 로고    scopus 로고
    • Socioeconomic disparities in health: pathways and policies. Inequality in education, income, and occupation exacerbates the gaps between the health "haves" and "have-nots"
    • Adler N.E., and Newman K. Socioeconomic disparities in health: pathways and policies. Inequality in education, income, and occupation exacerbates the gaps between the health "haves" and "have-nots". Health Aff. (Millwood) 21 (2002) 60-76
    • (2002) Health Aff. (Millwood) , vol.21 , pp. 60-76
    • Adler, N.E.1    Newman, K.2
  • 4
    • 0020066986 scopus 로고
    • Neonatal lead exposure alters the dendritic development of hippocampal dentate granule cells
    • Afano D.P., and Petit T.L. Neonatal lead exposure alters the dendritic development of hippocampal dentate granule cells. Exp. Neurol. 75 (1982) 275-288
    • (1982) Exp. Neurol. , vol.75 , pp. 275-288
    • Afano, D.P.1    Petit, T.L.2
  • 5
    • 0025125719 scopus 로고
    • Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead
    • Alkondon M., Costa A.C.S., Radhakrishnan V., Aronstam R.S., and Albuquerque E.X. Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead. FEBS Lett. 261 (1990) 124-130
    • (1990) FEBS Lett. , vol.261 , pp. 124-130
    • Alkondon, M.1    Costa, A.C.S.2    Radhakrishnan, V.3    Aronstam, R.S.4    Albuquerque, E.X.5
  • 7
    • 0033616590 scopus 로고    scopus 로고
    • Unusual phenotypic alteration of beta amyloid precursor protein (βAPP) maturation by a new Val-715→Met betaAPP-770 mutation responsible for probable early-onset Alzheimer's disease
    • Ancolio K., Dumanchin C., Barelli H., Warter J.M., Bric E.A., Campion D., Frebourg T., and Checler F. Unusual phenotypic alteration of beta amyloid precursor protein (βAPP) maturation by a new Val-715→Met betaAPP-770 mutation responsible for probable early-onset Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 4119-4124
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 4119-4124
    • Ancolio, K.1    Dumanchin, C.2    Barelli, H.3    Warter, J.M.4    Bric, E.A.5    Campion, D.6    Frebourg, T.7    Checler, F.8
  • 8
    • 0021723599 scopus 로고
    • Mechanism of action of lead on neuromuscular junction
    • Atchison W.D., and Narahashi T. Mechanism of action of lead on neuromuscular junction. Neurotoxicology 5 (1984) 267-282
    • (1984) Neurotoxicology , vol.5 , pp. 267-282
    • Atchison, W.D.1    Narahashi, T.2
  • 9
    • 0032893841 scopus 로고    scopus 로고
    • Fetal origins of cardiovascular disease
    • Barker D.J. Fetal origins of cardiovascular disease. Ann. Med. Supl. 1 (1999) 3-6
    • (1999) Ann. Med. Supl. , vol.1 , pp. 3-6
    • Barker, D.J.1
  • 10
    • 0036833795 scopus 로고    scopus 로고
    • Fetal programming of coronary heart disease
    • Barker D.J. Fetal programming of coronary heart disease. Trends Endocrinol. Metab. 13 (2002) 364-368
    • (2002) Trends Endocrinol. Metab. , vol.13 , pp. 364-368
    • Barker, D.J.1
  • 11
    • 9644296438 scopus 로고    scopus 로고
    • Developmental origins of adult health and disease
    • Barker D.J. Developmental origins of adult health and disease. J. Epidemiol. Community Health 58 (2004) 114-115
    • (2004) J. Epidemiol. Community Health , vol.58 , pp. 114-115
    • Barker, D.J.1
  • 12
    • 0024469193 scopus 로고
    • Weight in infancy and death from ischaemic heart disease
    • Barker D.J., Winter P.D., Osmond C., Margetts B., and Simmonds S.J. Weight in infancy and death from ischaemic heart disease. Lancet 2 8663 (1989) 577-580
    • (1989) Lancet , vol.2 , Issue.8663 , pp. 577-580
    • Barker, D.J.1    Winter, P.D.2    Osmond, C.3    Margetts, B.4    Simmonds, S.J.5
  • 13
    • 0028819961 scopus 로고
    • Neurotoxic effects of neonatal triethyltin (TET) exposure are exacerbated with aging
    • Barone Jr. S., Stanton M.E., and Mundy W.R. Neurotoxic effects of neonatal triethyltin (TET) exposure are exacerbated with aging. Neurobiol. Aging 16 (1995) 723-735
    • (1995) Neurobiol. Aging , vol.16 , pp. 723-735
    • Barone Jr., S.1    Stanton, M.E.2    Mundy, W.R.3
  • 14
    • 12844273354 scopus 로고    scopus 로고
    • The fetal-basis of amyloidogenesis: exposure to lead and latent over-expression of amyloid precursor protein and β-amyloid in the aging brain
    • Basha M.R., Wei W., Bakheet S.A., Benitez N., Siddiqi H.K., Ge Y., Lahiri D.K., and Zawia N.H. The fetal-basis of amyloidogenesis: exposure to lead and latent over-expression of amyloid precursor protein and β-amyloid in the aging brain. J. Neurosci. 25 (2005) 823-829
    • (2005) J. Neurosci. , vol.25 , pp. 823-829
    • Basha, M.R.1    Wei, W.2    Bakheet, S.A.3    Benitez, N.4    Siddiqi, H.K.5    Ge, Y.6    Lahiri, D.K.7    Zawia, N.H.8
  • 16
    • 33645548280 scopus 로고    scopus 로고
    • Childhood lead poisoning: the tortuous path from science to policy
    • Bellinger D.C., and Bellinger A.M. Childhood lead poisoning: the tortuous path from science to policy. J. Clin. Invest. 116 (2006) 853-857
    • (2006) J. Clin. Invest. , vol.116 , pp. 853-857
    • Bellinger, D.C.1    Bellinger, A.M.2
  • 18
    • 0033782015 scopus 로고    scopus 로고
    • Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
    • Bertolotti A., Zhang Y., Hendershot L.M., Harding H.P., and Ron D. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat. Cell Biol. 2 (2000) 326-332
    • (2000) Nat. Cell Biol. , vol.2 , pp. 326-332
    • Bertolotti, A.1    Zhang, Y.2    Hendershot, L.M.3    Harding, H.P.4    Ron, D.5
  • 19
    • 1842507631 scopus 로고    scopus 로고
    • Alzheimer's disease: one disorder, too many genes?
    • Bertram L., and Tanzi R.E. Alzheimer's disease: one disorder, too many genes?. Hum. Mol. Genet. 13 (2004) R135-R141
    • (2004) Hum. Mol. Genet. , vol.13
    • Bertram, L.1    Tanzi, R.E.2
  • 21
    • 2342475801 scopus 로고    scopus 로고
    • Interleukin 1alpha and interleukin 6 protect human neuronal SH-SY5Y cells from oxidative damage
    • Bissonnette C.J., Klegeris A., McGeer P.L., and McGeer E.G. Interleukin 1alpha and interleukin 6 protect human neuronal SH-SY5Y cells from oxidative damage. Neurosci. Lett. 361 (2004) 40-43
    • (2004) Neurosci. Lett. , vol.361 , pp. 40-43
    • Bissonnette, C.J.1    Klegeris, A.2    McGeer, P.L.3    McGeer, E.G.4
  • 22
    • 0027476024 scopus 로고
    • A synaptic model of memory: long-term potentiation in the hippocampus
    • Bliss T.V.P., and Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361 (1993) 31-39
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.P.1    Collingridge, G.L.2
  • 23
    • 0038069367 scopus 로고    scopus 로고
    • Birth insult interacts with stress at adulthood to alter dopaminergic function in animal models: possible implications for schizophrenia and other disorders
    • Boksa P., and El-Khodor B.F. Birth insult interacts with stress at adulthood to alter dopaminergic function in animal models: possible implications for schizophrenia and other disorders. Neurosci. Biobehav. Rev. 27 (2003) 91-101
    • (2003) Neurosci. Biobehav. Rev. , vol.27 , pp. 91-101
    • Boksa, P.1    El-Khodor, B.F.2
  • 24
    • 0036789082 scopus 로고    scopus 로고
    • Increased vulnerability of dopaminergic neurons in MPTP-lesioned interleukin-6 deficient mice
    • Bolin L.M., Strycharska-Orczyk I., Murray R., Langston J.W., and Di Monte D. Increased vulnerability of dopaminergic neurons in MPTP-lesioned interleukin-6 deficient mice. J. Neurochem. 83 (2002) 167-175
    • (2002) J. Neurochem. , vol.83 , pp. 167-175
    • Bolin, L.M.1    Strycharska-Orczyk, I.2    Murray, R.3    Langston, J.W.4    Di Monte, D.5
  • 26
    • 0036414219 scopus 로고    scopus 로고
    • Socioeconomic status and child development
    • Bradley R.H., and Corwyn R.F. Socioeconomic status and child development. Ann. Rev. Psychol. 53 (2002) 371-399
    • (2002) Ann. Rev. Psychol. , vol.53 , pp. 371-399
    • Bradley, R.H.1    Corwyn, R.F.2
  • 27
    • 0033599801 scopus 로고    scopus 로고
    • Nanomolar concentrations of lead inhibit glutamatergic and GABAergic transmission in hippocampal neurons
    • Braga M.F.M., Pereira E.F.R., and Albuquerque E.X. Nanomolar concentrations of lead inhibit glutamatergic and GABAergic transmission in hippocampal neurons. Brain Res. 826 (1999) 22-34
    • (1999) Brain Res. , vol.826 , pp. 22-34
    • Braga, M.F.M.1    Pereira, E.F.R.2    Albuquerque, E.X.3
  • 28
    • 0033599787 scopus 로고    scopus 로고
    • Lead increases tetrodotoxin-insensitive spontaneous release of glutamate and GABA from hippocampal neurons
    • Braga M.F.M., Pereira E.F.R., Marchioro M., and Albuquerque E.X. Lead increases tetrodotoxin-insensitive spontaneous release of glutamate and GABA from hippocampal neurons. Brain Res. 826 (1999) 10-21
    • (1999) Brain Res. , vol.826 , pp. 10-21
    • Braga, M.F.M.1    Pereira, E.F.R.2    Marchioro, M.3    Albuquerque, E.X.4
  • 29
    • 0028671804 scopus 로고
    • 2+ reduces voltage- and N-methyl-d-aspartate (NMDA)-activated calcium channel currents
    • 2+ reduces voltage- and N-methyl-d-aspartate (NMDA)-activated calcium channel currents. Cell. Mol. Neurobiol. 14 (1994) 711-722
    • (1994) Cell. Mol. Neurobiol. , vol.14 , pp. 711-722
    • Büsselberg, D.1    Michael, D.2    Platt, B.3
  • 32
    • 3943069731 scopus 로고    scopus 로고
    • Impaired neuropsychological functioning in lead-exposed children
    • Canfield R.L., Gendle M.H., and Cory-Slechta D.A. Impaired neuropsychological functioning in lead-exposed children. Dev. Neuropsychol. 26 (2004) 513-540
    • (2004) Dev. Neuropsychol. , vol.26 , pp. 513-540
    • Canfield, R.L.1    Gendle, M.H.2    Cory-Slechta, D.A.3
  • 33
    • 0034664939 scopus 로고    scopus 로고
    • Cytosine methylation of an Sp1 site contributes to organ-specific and cell-specific regulation of expression of the lung epithelial gene t1alpha
    • Cao Y.X., Jean J.C., and Williams M.C. Cytosine methylation of an Sp1 site contributes to organ-specific and cell-specific regulation of expression of the lung epithelial gene t1alpha. Biochem. J. 350 (2000) 883-890
    • (2000) Biochem. J. , vol.350 , pp. 883-890
    • Cao, Y.X.1    Jean, J.C.2    Williams, M.C.3
  • 34
    • 0030841343 scopus 로고    scopus 로고
    • Conformational disease
    • Carrell R.W., and Lomas D.A. Conformational disease. Lancet 350 (1997) 134-138
    • (1997) Lancet , vol.350 , pp. 134-138
    • Carrell, R.W.1    Lomas, D.A.2
  • 35
    • 1642416888 scopus 로고    scopus 로고
    • Editorial: Glucocorticoid action networks-an introduction to systems biology
    • Chrousos G.C.E., and Kino T. Editorial: Glucocorticoid action networks-an introduction to systems biology. J. Clin. Endocrinol. Metab. 89 (2004) 563-564
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 563-564
    • Chrousos, G.C.E.1    Kino, T.2
  • 36
    • 0030746884 scopus 로고    scopus 로고
    • Sp1 binding is inhibited by (m)Cp(m)CpG methylation
    • Clark S.J., Harrison J., and Molloy P.L. Sp1 binding is inhibited by (m)Cp(m)CpG methylation. Gene 195 (1997) 67-71
    • (1997) Gene , vol.195 , pp. 67-71
    • Clark, S.J.1    Harrison, J.2    Molloy, P.L.3
  • 37
    • 0029838524 scopus 로고    scopus 로고
    • Low lead levels stunt neuronal growth in a reversible manner
    • Cline H.T., Witte S., and Jones K.W. Low lead levels stunt neuronal growth in a reversible manner. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 9915-9920
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 9915-9920
    • Cline, H.T.1    Witte, S.2    Jones, K.W.3
  • 38
    • 0023180067 scopus 로고
    • NMDA receptors - their role in long-term potentiation
    • Collingridge G.L., and Bliss T.V.P. NMDA receptors - their role in long-term potentiation. Trends Neuropharm. 10 (1987) 288-293
    • (1987) Trends Neuropharm. , vol.10 , pp. 288-293
    • Collingridge, G.L.1    Bliss, T.V.P.2
  • 39
    • 0027492258 scopus 로고
    • Subsensitivity of lead-exposed rats to the accuracy-impairing and rate-altering effects of MK-801 on a multiple schedule of repeated learning and performance
    • Cohn J., and Cory-Slechta D.A. Subsensitivity of lead-exposed rats to the accuracy-impairing and rate-altering effects of MK-801 on a multiple schedule of repeated learning and performance. Brain Res. 600 (1993) 208-218
    • (1993) Brain Res. , vol.600 , pp. 208-218
    • Cohn, J.1    Cory-Slechta, D.A.2
  • 40
    • 0030769092 scopus 로고    scopus 로고
    • Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells
    • Cook D.G., Forman M.S., Sung J.C., Leight S., Kolson D.L., Iwatsubo T., Lee V.M., and Doms R.W. Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells. Nat. Med. 3 (1997) 1021-1023
    • (1997) Nat. Med. , vol.3 , pp. 1021-1023
    • Cook, D.G.1    Forman, M.S.2    Sung, J.C.3    Leight, S.4    Kolson, D.L.5    Iwatsubo, T.6    Lee, V.M.7    Doms, R.W.8
  • 41
    • 0023253938 scopus 로고
    • Chronic low-level lead exposure impairs embryonic to adult conversion of the neural cell adhesion molecule
    • Cookman G.R., King W., and Regan C.M. Chronic low-level lead exposure impairs embryonic to adult conversion of the neural cell adhesion molecule. J. Neurochem. 49 (1987) 399-403
    • (1987) J. Neurochem. , vol.49 , pp. 399-403
    • Cookman, G.R.1    King, W.2    Regan, C.M.3
  • 42
    • 0028986972 scopus 로고
    • MK-801 subsensitivity following postweaning lead exposure
    • Cory-Slechta D.A. MK-801 subsensitivity following postweaning lead exposure. Neurotoxicology 16 (1995) 83-95
    • (1995) Neurotoxicology , vol.16 , pp. 83-95
    • Cory-Slechta, D.A.1
  • 43
    • 0031011342 scopus 로고    scopus 로고
    • Postnatal lead exposure and MK-801 sensitivity
    • Cory-Slechta D.A. Postnatal lead exposure and MK-801 sensitivity. Neurotoxicology 18 (1997) 209-220
    • (1997) Neurotoxicology , vol.18 , pp. 209-220
    • Cory-Slechta, D.A.1
  • 44
    • 23844515740 scopus 로고    scopus 로고
    • Studying toxicants as single chemicals: does this strategy adequately identify neurotoxic risk?
    • Cory-Slechta D.A. Studying toxicants as single chemicals: does this strategy adequately identify neurotoxic risk?. Neurotoxicology 26 (2005) 491-510
    • (2005) Neurotoxicology , vol.26 , pp. 491-510
    • Cory-Slechta, D.A.1
  • 46
    • 0032982089 scopus 로고    scopus 로고
    • Obstetric complications and the risk of schizophrenia: a longitudinal study of a national birth cohort
    • Dalman C., Allebeck P., Cullberg J., Grunewald C., and Koster M. Obstetric complications and the risk of schizophrenia: a longitudinal study of a national birth cohort. Arch. Gen. Psychiatry 56 (1999) 234-240
    • (1999) Arch. Gen. Psychiatry , vol.56 , pp. 234-240
    • Dalman, C.1    Allebeck, P.2    Cullberg, J.3    Grunewald, C.4    Koster, M.5
  • 47
    • 0027317818 scopus 로고
    • Lead increases inositol 1,4,5-trisphosphate levels but does not interfere with calcium transients in primary rat astrocytes
    • Dave V., Vitarella D., Aschner J.L., Fletcher P., Kimelberg H.K., and Aschner M. Lead increases inositol 1,4,5-trisphosphate levels but does not interfere with calcium transients in primary rat astrocytes. Brain Res. 618 (1993) 9-18
    • (1993) Brain Res. , vol.618 , pp. 9-18
    • Dave, V.1    Vitarella, D.2    Aschner, J.L.3    Fletcher, P.4    Kimelberg, H.K.5    Aschner, M.6
  • 48
    • 0023512593 scopus 로고
    • Selective effects of lead on the hormonal regulation of glial cell differentiation in cell culture
    • de Vellis J., McGinnis J.F., and Cole R. Selective effects of lead on the hormonal regulation of glial cell differentiation in cell culture. Prog. Clin. Biol. Res. 253 (1987) 217-227
    • (1987) Prog. Clin. Biol. Res. , vol.253 , pp. 217-227
    • de Vellis, J.1    McGinnis, J.F.2    Cole, R.3
  • 49
    • 0035420403 scopus 로고    scopus 로고
    • Lead exposure delays the differentiation of oligodendroglial progenitors in vitro
    • Deng W., McKinnon R.D., and Poretz R.D. Lead exposure delays the differentiation of oligodendroglial progenitors in vitro. Toxicol. Appl. Pharmacol. 174 (2001) 235-244
    • (2001) Toxicol. Appl. Pharmacol. , vol.174 , pp. 235-244
    • Deng, W.1    McKinnon, R.D.2    Poretz, R.D.3
  • 51
    • 0017611750 scopus 로고
    • The relationship between Parkinson syndrome and vascular siderosis: an electron microprobe study
    • Duckett S., Galle P., and Kradin R. The relationship between Parkinson syndrome and vascular siderosis: an electron microprobe study. Ann. Neurol. 2 (1977) 225-229
    • (1977) Ann. Neurol. , vol.2 , pp. 225-229
    • Duckett, S.1    Galle, P.2    Kradin, R.3
  • 53
    • 0025105951 scopus 로고
    • Glutamine synthetase activity of developing astrocytes is inhibited in vitro by very low concentrations of lead
    • Engle M.J., and Volpe J.J. Glutamine synthetase activity of developing astrocytes is inhibited in vitro by very low concentrations of lead. Brain Res. Dev. Brain Res. 55 (1990) 283-287
    • (1990) Brain Res. Dev. Brain Res. , vol.55 , pp. 283-287
    • Engle, M.J.1    Volpe, J.J.2
  • 55
    • 17444402049 scopus 로고    scopus 로고
    • The importance of glutamate, glycine, and gamma-aminobutyric acid transport and regulation in manganese, mercury and lead neurotoxicity
    • Fitsanakis V.A., and Aschner M. The importance of glutamate, glycine, and gamma-aminobutyric acid transport and regulation in manganese, mercury and lead neurotoxicity. Toxicol. Appl. Pharmacol. 204 (2005) 343-354
    • (2005) Toxicol. Appl. Pharmacol. , vol.204 , pp. 343-354
    • Fitsanakis, V.A.1    Aschner, M.2
  • 58
    • 0025333350 scopus 로고
    • The NMDA antagonist, MK-801, suppresses long-term potentiation, kindling, and kindling-induced potentiation in the perforant path of the unanesthetized rat
    • Gilbert M.E., and Mack C.M. The NMDA antagonist, MK-801, suppresses long-term potentiation, kindling, and kindling-induced potentiation in the perforant path of the unanesthetized rat. Brain Res. 519 (1990) 89-96
    • (1990) Brain Res. , vol.519 , pp. 89-96
    • Gilbert, M.E.1    Mack, C.M.2
  • 59
    • 0032489952 scopus 로고    scopus 로고
    • Chronic developmental lead exposure accelerated decay of long-term potentiation in rat dentate gyrus in vivo
    • Gilbert M.E., and Mack C.M. Chronic developmental lead exposure accelerated decay of long-term potentiation in rat dentate gyrus in vivo. Brain Res. 789 (1998) 139-149
    • (1998) Brain Res. , vol.789 , pp. 139-149
    • Gilbert, M.E.1    Mack, C.M.2
  • 60
    • 34248597071 scopus 로고    scopus 로고
    • Developmental lead (Pb) exposure reduces the ability of the NMDA antagonist MK801 to suppress long-term potentiation (LTP) in the rat dentate gyrus, in vivo
    • Gilbert M.E., and Lasley S.M. Developmental lead (Pb) exposure reduces the ability of the NMDA antagonist MK801 to suppress long-term potentiation (LTP) in the rat dentate gyrus, in vivo. Neurotoxicol. Teratol. 29 (2007) 385-393
    • (2007) Neurotoxicol. Teratol. , vol.29 , pp. 385-393
    • Gilbert, M.E.1    Lasley, S.M.2
  • 61
    • 0030583637 scopus 로고    scopus 로고
    • 2+) exposure increases threshold for long-term potentiation in the rat dentate gyrus in vivo
    • 2+) exposure increases threshold for long-term potentiation in the rat dentate gyrus in vivo. Brain Res. 736 (1996) 125-134
    • (1996) Brain Res. , vol.736 , pp. 125-134
    • Gilbert, M.E.1    Mack, C.M.2    Lasley, S.M.3
  • 62
    • 0032974871 scopus 로고    scopus 로고
    • The influence of developmental period of lead exposure on long-term potentiation in the rat dentate gyrus in vivo
    • Gilbert M.E., Mack C.M., and Lasley S.M. The influence of developmental period of lead exposure on long-term potentiation in the rat dentate gyrus in vivo. Neurotoxicology 20 (1999) 57-70
    • (1999) Neurotoxicology , vol.20 , pp. 57-70
    • Gilbert, M.E.1    Mack, C.M.2    Lasley, S.M.3
  • 63
    • 0032972911 scopus 로고    scopus 로고
    • Developmental lead exposure reduces the magnitude of long-term potentiation: a dose-response analysis
    • Gilbert M.E., Mack C.M., and Lasley S.M. Developmental lead exposure reduces the magnitude of long-term potentiation: a dose-response analysis. Neurotoxicology 20 (1999) 71-82
    • (1999) Neurotoxicology , vol.20 , pp. 71-82
    • Gilbert, M.E.1    Mack, C.M.2    Lasley, S.M.3
  • 64
    • 26444562983 scopus 로고    scopus 로고
    • Chronic developmental lead exposure reduces neurogenesis in adult rat hippocampus but does not impair spatial learning
    • Gilbert M.E., Kelly M.E., Samsam T.E., and Goodman J.H. Chronic developmental lead exposure reduces neurogenesis in adult rat hippocampus but does not impair spatial learning. Toxicol. Sci. 86 (2005) 365-374
    • (2005) Toxicol. Sci. , vol.86 , pp. 365-374
    • Gilbert, M.E.1    Kelly, M.E.2    Samsam, T.E.3    Goodman, J.H.4
  • 65
    • 0021207461 scopus 로고
    • Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein
    • Glenner G.G., and Wong C.W. Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem. Biophys. Res. Commun. 122 (1984) 1131-1135
    • (1984) Biochem. Biophys. Res. Commun. , vol.122 , pp. 1131-1135
    • Glenner, G.G.1    Wong, C.W.2
  • 66
    • 4544366928 scopus 로고    scopus 로고
    • Living with the past: evolution, development, and patterns of disease
    • Gluckman P.D., and Hanson M.A. Living with the past: evolution, development, and patterns of disease. Science 305 (2004) 1733-1736
    • (2004) Science , vol.305 , pp. 1733-1736
    • Gluckman, P.D.1    Hanson, M.A.2
  • 67
    • 0023506466 scopus 로고
    • Isolation, characterization, and chromosomal localization of human brain cDNA clones coding for the precursor of the amyloid of brain in Alzheimer's disease, Down's syndrome and aging
    • Goldgaber D., Lerman M.I., McBride W.O., Saffiotti U., and Gajdusek D.C. Isolation, characterization, and chromosomal localization of human brain cDNA clones coding for the precursor of the amyloid of brain in Alzheimer's disease, Down's syndrome and aging. J. Neural Transm., Suppl. 24 (1987) 23-28
    • (1987) J. Neural Transm., Suppl. , vol.24 , pp. 23-28
    • Goldgaber, D.1    Lerman, M.I.2    McBride, W.O.3    Saffiotti, U.4    Gajdusek, D.C.5
  • 68
    • 0036285989 scopus 로고    scopus 로고
    • Lead, renal disease and hypertension
    • Gonick H.C. Lead, renal disease and hypertension. Am. J. Kidney Dis. 40 (2002) 202-204
    • (2002) Am. J. Kidney Dis. , vol.40 , pp. 202-204
    • Gonick, H.C.1
  • 72
    • 0031301027 scopus 로고    scopus 로고
    • Physiological and pathological roles of interleukin-6 in the central nervous system
    • Gruol D.L., and Nelson T.E. Physiological and pathological roles of interleukin-6 in the central nervous system. Mol. Neurobiol. 15 (1997) 307-339
    • (1997) Mol. Neurobiol. , vol.15 , pp. 307-339
    • Gruol, D.L.1    Nelson, T.E.2
  • 73
    • 0026619470 scopus 로고
    • 3H]MK-801 binding to the NMDA receptor-gated ionophore: In vitro and in vivo studies
    • 3H]MK-801 binding to the NMDA receptor-gated ionophore: In vitro and in vivo studies. Neurosci. Lett. 148 (1992) 27-30
    • (1992) Neurosci. Lett. , vol.148 , pp. 27-30
    • Guilarte, T.R.1    Miceli, R.C.2
  • 76
    • 0028246308 scopus 로고
    • Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor
    • Haass C., Hung A.Y., Selkoe D.J., and Teplow D.B. Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor. J. Biol. Chem. 269 (1994) 17741-17748
    • (1994) J. Biol. Chem. , vol.269 , pp. 17741-17748
    • Haass, C.1    Hung, A.Y.2    Selkoe, D.J.3    Teplow, D.B.4
  • 77
    • 0036849018 scopus 로고    scopus 로고
    • Microglia as a source and target of cytokines
    • Hanisch U.K. Microglia as a source and target of cytokines. Glia 40 (2002) 140-155
    • (2002) Glia , vol.40 , pp. 140-155
    • Hanisch, U.K.1
  • 81
    • 33745246032 scopus 로고    scopus 로고
    • Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4
    • Ho S., Tang W., de Frausto B., and Prins G.S. Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4. Cancer Res. 66 (2006) 5624-5632
    • (2006) Cancer Res. , vol.66 , pp. 5624-5632
    • Ho, S.1    Tang, W.2    de Frausto, B.3    Prins, G.S.4
  • 82
    • 0029063726 scopus 로고
    • DNA binding and regulatory effects of transcription factors SP1 and USF at the rat amyloid protein gene promoter
    • Hoffman P.W., and Chernak J.M. DNA binding and regulatory effects of transcription factors SP1 and USF at the rat amyloid protein gene promoter. Nucleic Acids Res. 23 (1995) 2229-2235
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2229-2235
    • Hoffman, P.W.1    Chernak, J.M.2
  • 83
    • 0021687518 scopus 로고
    • Maturation of resistance to lead encephalopathy: cellular and subcellular mechanisms
    • Holtzman D., DeVries C., Nguyen H., Olson J., and Bensch K. Maturation of resistance to lead encephalopathy: cellular and subcellular mechanisms. Neurotoxicology 5 (1984) 97-124
    • (1984) Neurotoxicology , vol.5 , pp. 97-124
    • Holtzman, D.1    DeVries, C.2    Nguyen, H.3    Olson, J.4    Bensch, K.5
  • 84
    • 0023258018 scopus 로고
    • Lead toxicity in primary cultured cerebral astrocytes and cerebellar granular neurons
    • Holtzman D., Olson J.E., DeVries C., and Bensch K. Lead toxicity in primary cultured cerebral astrocytes and cerebellar granular neurons. Toxicol. Appl. Pharmacol. 89 (1987) 211-225
    • (1987) Toxicol. Appl. Pharmacol. , vol.89 , pp. 211-225
    • Holtzman, D.1    Olson, J.E.2    DeVries, C.3    Bensch, K.4
  • 85
    • 13244300647 scopus 로고    scopus 로고
    • Exposure of astrocytes to hypoxia/reoxygenation enhances expression of glucose-regulated protein 78 facilitating astrocyte release of the neuroprotective cytokine interleukin 6
    • Hori O., Matsumoto M., Kuwabara K., Maeda Y., Ueda H., Ohtsuki T., Kinoshita T., Ogawa S., Stern D.M., and Kamada T. Exposure of astrocytes to hypoxia/reoxygenation enhances expression of glucose-regulated protein 78 facilitating astrocyte release of the neuroprotective cytokine interleukin 6. J. Neurochem. 66 (1996) 973-979
    • (1996) J. Neurochem. , vol.66 , pp. 973-979
    • Hori, O.1    Matsumoto, M.2    Kuwabara, K.3    Maeda, Y.4    Ueda, H.5    Ohtsuki, T.6    Kinoshita, T.7    Ogawa, S.8    Stern, D.M.9    Kamada, T.10
  • 86
    • 0031888609 scopus 로고    scopus 로고
    • Bone lead as a biological marker in epidemiologic studies of chronic toxicity: conceptual paradigms
    • Hu H., Rabinowitz M., and Smith D. Bone lead as a biological marker in epidemiologic studies of chronic toxicity: conceptual paradigms. Environ. Health Perspect. 106 (1998) 1-8
    • (1998) Environ. Health Perspect. , vol.106 , pp. 1-8
    • Hu, H.1    Rabinowitz, M.2    Smith, D.3
  • 87
    • 0029052109 scopus 로고
    • Ontogenically related properties of N-methyl-d-aspartate receptors in rat hippocampal neurons and the age-specific sensitivity of developing neurons to lead
    • Ishihara K., Alkondon M., Montes J.G., and Albuquerque E.X. Ontogenically related properties of N-methyl-d-aspartate receptors in rat hippocampal neurons and the age-specific sensitivity of developing neurons to lead. J. Pharmacol. Exp. Ther. 273 (1995) 1459-1470
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 1459-1470
    • Ishihara, K.1    Alkondon, M.2    Montes, J.G.3    Albuquerque, E.X.4
  • 89
    • 0019795736 scopus 로고
    • Neonatal lead exposure: effects on development of behavior and striatal dopamine neurons
    • Jason K.M., and Kellogg C.K. Neonatal lead exposure: effects on development of behavior and striatal dopamine neurons. Pharmacol. Biochem. Behav. 15 (1981) 641-649
    • (1981) Pharmacol. Biochem. Behav. , vol.15 , pp. 641-649
    • Jason, K.M.1    Kellogg, C.K.2
  • 90
    • 0025032104 scopus 로고
    • Induction of fos-like immunoreactivity and the maintenance of long-term potentiation in the dentate gyrus of unanesthetized rats
    • Jeffery K.J., Abraham W.C., Dragunow M., and Mason S.E. Induction of fos-like immunoreactivity and the maintenance of long-term potentiation in the dentate gyrus of unanesthetized rats. Mol. Brain Res. 8 (1990) 267-274
    • (1990) Mol. Brain Res. , vol.8 , pp. 267-274
    • Jeffery, K.J.1    Abraham, W.C.2    Dragunow, M.3    Mason, S.E.4
  • 91
    • 0028260545 scopus 로고
    • Mineralocorticoid and glucocorticoid receptors in the brain. Implications for ion permeability and transmitter systems
    • Joels M., and de Kloet E.R. Mineralocorticoid and glucocorticoid receptors in the brain. Implications for ion permeability and transmitter systems. Prog. Neurobiol. 43 (1994) 1-36
    • (1994) Prog. Neurobiol. , vol.43 , pp. 1-36
    • Joels, M.1    de Kloet, E.R.2
  • 94
    • 0036431351 scopus 로고    scopus 로고
    • Relationships among socioeconomic status, stress induced changes in cortisol, and blood pressure in African American males
    • Kapuku G.L., Treiber F.A., and Davis H.C. Relationships among socioeconomic status, stress induced changes in cortisol, and blood pressure in African American males. Ann. Behav. Med. 24 (2002) 320-325
    • (2002) Ann. Behav. Med. , vol.24 , pp. 320-325
    • Kapuku, G.L.1    Treiber, F.A.2    Davis, H.C.3
  • 96
    • 0033562966 scopus 로고    scopus 로고
    • Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls
    • Kaufman R.J. Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev. 13 (1999) 1211-1233
    • (1999) Genes Dev. , vol.13 , pp. 1211-1233
    • Kaufman, R.J.1
  • 97
    • 0142042983 scopus 로고    scopus 로고
    • Depressed new neurons-adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression
    • Kempermann G., and Kronenberg G. Depressed new neurons-adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression. Biol. Psychiatry 54 (2003) 499-503
    • (2003) Biol. Psychiatry , vol.54 , pp. 499-503
    • Kempermann, G.1    Kronenberg, G.2
  • 98
    • 0029118303 scopus 로고
    • Inorganic lead may inhibit neurite development in cultured rat hippocampal neurons through hyperphosphorylation
    • Kern M., and Audesirk G. Inorganic lead may inhibit neurite development in cultured rat hippocampal neurons through hyperphosphorylation. Toxicol. Appl. Pharmacol. 134 (1995) 111-123
    • (1995) Toxicol. Appl. Pharmacol. , vol.134 , pp. 111-123
    • Kern, M.1    Audesirk, G.2
  • 99
    • 0038308388 scopus 로고    scopus 로고
    • Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins
    • Kimata Y., Kimata Y.I., Shimizu Y., Abe H., Farcasanu I.C., Takeuchi M., Rose M.D., and Kohno K. Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins. Mol. Biol. Cell 14 (2003) 2559-2569
    • (2003) Mol. Biol. Cell , vol.14 , pp. 2559-2569
    • Kimata, Y.1    Kimata, Y.I.2    Shimizu, Y.3    Abe, H.4    Farcasanu, I.C.5    Takeuchi, M.6    Rose, M.D.7    Kohno, K.8
  • 100
    • 0017183838 scopus 로고
    • Lead competitively inhibits calcium-dependent synaptic transmission in the bullfrog sympathetic ganglion
    • Kober T.E., and Cooper G.P. Lead competitively inhibits calcium-dependent synaptic transmission in the bullfrog sympathetic ganglion. Nature 262 (1976) 704-705
    • (1976) Nature , vol.262 , pp. 704-705
    • Kober, T.E.1    Cooper, G.P.2
  • 102
    • 2642546665 scopus 로고    scopus 로고
    • A novel mechanism for the facilitation of theta-induced long-term potentiation by brain-derived neurotrophic factor
    • Kramar E.A., Lin B., Lin C.Y., Arai A.C., Gall C.M., and Lynch G. A novel mechanism for the facilitation of theta-induced long-term potentiation by brain-derived neurotrophic factor. J. Neurosci. 24 (2004) 5151-5161
    • (2004) J. Neurosci. , vol.24 , pp. 5151-5161
    • Kramar, E.A.1    Lin, B.2    Lin, C.Y.3    Arai, A.C.4    Gall, C.M.5    Lynch, G.6
  • 104
    • 0031746196 scopus 로고    scopus 로고
    • High prevalence of parkinsonism after occupational exposure to lead-sulfate batteries
    • Kuhn W., Winkel R., Woitalla D., Meves S., Przuntek H., and Muller T. High prevalence of parkinsonism after occupational exposure to lead-sulfate batteries. Neurology 50 (1998) 1885-1886
    • (1998) Neurology , vol.50 , pp. 1885-1886
    • Kuhn, W.1    Winkel, R.2    Woitalla, D.3    Meves, S.4    Przuntek, H.5    Muller, T.6
  • 105
    • 0030583651 scopus 로고    scopus 로고
    • Presynaptic glutamatergic function in hippocampal dentate gyrus is diminished by chronic exposure to inorganic lead
    • Lasley S.M., and Gilbert M.E. Presynaptic glutamatergic function in hippocampal dentate gyrus is diminished by chronic exposure to inorganic lead. Brain Res. 736 (1996) 125-134
    • (1996) Brain Res. , vol.736 , pp. 125-134
    • Lasley, S.M.1    Gilbert, M.E.2
  • 106
    • 0032845759 scopus 로고    scopus 로고
    • Lead inhibits the rat N-methyl-d-aspartate receptor channel by binding to a site distinct from the zinc allosteric site
    • Lasley S.M., and Gilbert M.E. Lead inhibits the rat N-methyl-d-aspartate receptor channel by binding to a site distinct from the zinc allosteric site. Toxicol. Appl. Pharmacol. 159 (1999) 224-233
    • (1999) Toxicol. Appl. Pharmacol. , vol.159 , pp. 224-233
    • Lasley, S.M.1    Gilbert, M.E.2
  • 107
    • 0034471862 scopus 로고    scopus 로고
    • Glutamatergic components underlying lead-induced impairments in hippocampal synaptic plasticity
    • Lasley S.M., and Gilbert M.E. Glutamatergic components underlying lead-induced impairments in hippocampal synaptic plasticity. Neurotoxicology 21 (2000) 1057-1068
    • (2000) Neurotoxicology , vol.21 , pp. 1057-1068
    • Lasley, S.M.1    Gilbert, M.E.2
  • 108
    • 0036190004 scopus 로고    scopus 로고
    • Rat hippocampal glutamate and GABA release exhibit biphasic effects as a function of chronic lead exposure level
    • Lasley S.M., and Gilbert M.E. Rat hippocampal glutamate and GABA release exhibit biphasic effects as a function of chronic lead exposure level. Toxicol. Sci. 66 (2002) 139-147
    • (2002) Toxicol. Sci. , vol.66 , pp. 139-147
    • Lasley, S.M.1    Gilbert, M.E.2
  • 109
    • 33645362520 scopus 로고    scopus 로고
    • Impairment of synaptic function by exposure to lead
    • Tiffany-Castiglioni E. (Ed), Humana Press, Totowa, N.J.
    • Lasley S.M., and Gilbert M.E. Impairment of synaptic function by exposure to lead. In: Tiffany-Castiglioni E. (Ed). In Vitro Neurotoxicology: Principles and Challenges (2004), Humana Press, Totowa, N.J. 217-241
    • (2004) In Vitro Neurotoxicology: Principles and Challenges , pp. 217-241
    • Lasley, S.M.1    Gilbert, M.E.2
  • 110
    • 0032881032 scopus 로고    scopus 로고
    • Influence of exposure period on in vivo hippocampal glutamate and GABA release in rats chronically exposed to lead
    • Lasley S.M., Green M.C., and Gilbert M.E. Influence of exposure period on in vivo hippocampal glutamate and GABA release in rats chronically exposed to lead. Neurotoxicology 20 (1999) 619-630
    • (1999) Neurotoxicology , vol.20 , pp. 619-630
    • Lasley, S.M.1    Green, M.C.2    Gilbert, M.E.3
  • 111
    • 0035022546 scopus 로고    scopus 로고
    • Rat hippocampal N-methyl-d-aspartate receptor binding as a function of the level of chronic lead exposure
    • Lasley S.M., Green M.C., and Gilbert M.E. Rat hippocampal N-methyl-d-aspartate receptor binding as a function of the level of chronic lead exposure. Neurotoxicol. Teratol. 23 (2001) 185-189
    • (2001) Neurotoxicol. Teratol. , vol.23 , pp. 185-189
    • Lasley, S.M.1    Green, M.C.2    Gilbert, M.E.3
  • 112
    • 0026734018 scopus 로고
    • Premature decline in Morris water maze performance of aging micrencephalic rats
    • Lee M.H., and Rabe A. Premature decline in Morris water maze performance of aging micrencephalic rats. Neurotoxicol. Teratol. 14 (1992) 383-392
    • (1992) Neurotoxicol. Teratol. , vol.14 , pp. 383-392
    • Lee, M.H.1    Rabe, A.2
  • 113
    • 0027496026 scopus 로고
    • Low-level lead exposure in cultured astroglia: identification of cellular targets with vital fluorescent probes
    • Legare M.E., Barhoumi R., Burghardt R.C., and Tiffany-Castiglioni E. Low-level lead exposure in cultured astroglia: identification of cellular targets with vital fluorescent probes. Neurotoxicology 14 (1993) 267-272
    • (1993) Neurotoxicology , vol.14 , pp. 267-272
    • Legare, M.E.1    Barhoumi, R.2    Burghardt, R.C.3    Tiffany-Castiglioni, E.4
  • 115
    • 20444411948 scopus 로고    scopus 로고
    • Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
    • Lillycrop K.A., Phillips E.S., Jackson A.A., Hanson M.A., and Burdge G.C. Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J. Nutr. 135 (2005) 1382-1386
    • (2005) J. Nutr. , vol.135 , pp. 1382-1386
    • Lillycrop, K.A.1    Phillips, E.S.2    Jackson, A.A.3    Hanson, M.A.4    Burdge, G.C.5
  • 116
    • 0032816902 scopus 로고    scopus 로고
    • Differential ability of astroglia and neuronal cells to accumulate lead: dependence on cell type and on degree of differentiation
    • Lindahl L.S., Bird L., Legare M.E., Mikeska G., Bratton G.R., and Tiffany-Castiglioni E. Differential ability of astroglia and neuronal cells to accumulate lead: dependence on cell type and on degree of differentiation. Toxicol. Sci. 50 (1999) 236-243
    • (1999) Toxicol. Sci. , vol.50 , pp. 236-243
    • Lindahl, L.S.1    Bird, L.2    Legare, M.E.3    Mikeska, G.4    Bratton, G.R.5    Tiffany-Castiglioni, E.6
  • 117
    • 0027958873 scopus 로고
    • The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications
    • Little E., Ramakrishnan M., Roy B., Gazit G., and Lee A.S. The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications. Crit. Rev. Eukaryot. Gene Expr. 4 (1994) 1-18
    • (1994) Crit. Rev. Eukaryot. Gene Expr. , vol.4 , pp. 1-18
    • Little, E.1    Ramakrishnan, M.2    Roy, B.3    Gazit, G.4    Lee, A.S.5
  • 118
    • 0034637605 scopus 로고    scopus 로고
    • Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum
    • Liu C.Y., Schroder M., and Kaufman R.J. Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum. J. Biol. Chem. 275 (2000) 24881-24885
    • (2000) J. Biol. Chem. , vol.275 , pp. 24881-24885
    • Liu, C.Y.1    Schroder, M.2    Kaufman, R.J.3
  • 119
    • 33644507720 scopus 로고    scopus 로고
    • Adult neurogenesis and functional plasticity in neuronal circuits
    • Lledo P.M., Alonso M., and Grubb M.S. Adult neurogenesis and functional plasticity in neuronal circuits. Nat. Rev., Neurosci. 7 (2006) 7179-7193
    • (2006) Nat. Rev., Neurosci. , vol.7 , pp. 7179-7193
    • Lledo, P.M.1    Alonso, M.2    Grubb, M.S.3
  • 120
    • 0028009876 scopus 로고
    • Protein-DNA interactions in the promoter region of the amyloid precursor protein (APP) gene in human neocortex
    • Lukiw W.J., Rogaev E.I., Wong L., Vaula G., McLachlan D.R., and St. George Hyslop P. Protein-DNA interactions in the promoter region of the amyloid precursor protein (APP) gene in human neocortex. Mol. Brain Res. 22 (1994) 121-131
    • (1994) Mol. Brain Res. , vol.22 , pp. 121-131
    • Lukiw, W.J.1    Rogaev, E.I.2    Wong, L.3    Vaula, G.4    McLachlan, D.R.5    St. George Hyslop, P.6
  • 121
    • 0034669747 scopus 로고    scopus 로고
    • Child's stress hormone levels correlate with mother's socioeconomic status and depressive state
    • Lupien S.J., King S., Meaney M.J., and McEwen B.S. Child's stress hormone levels correlate with mother's socioeconomic status and depressive state. Biol. Psychiatry 48 (2000) 976-980
    • (2000) Biol. Psychiatry , vol.48 , pp. 976-980
    • Lupien, S.J.1    King, S.2    Meaney, M.J.3    McEwen, B.S.4
  • 122
    • 0035354558 scopus 로고    scopus 로고
    • Can poverty get under your skin? Basal cortisol levels and cognitive function in children from low and high socioeconomic status
    • Lupien S.J., King S., Meaney M.J., and McEwen B.S. Can poverty get under your skin? Basal cortisol levels and cognitive function in children from low and high socioeconomic status. Dev. Psychopathol. 13 (2001) 653-676
    • (2001) Dev. Psychopathol. , vol.13 , pp. 653-676
    • Lupien, S.J.1    King, S.2    Meaney, M.J.3    McEwen, B.S.4
  • 123
    • 0013632244 scopus 로고
    • Some landmarks in the history of lead poisoning
    • Major R.H. Some landmarks in the history of lead poisoning. Ann. Med. Hist. 3 (1931) 218-227
    • (1931) Ann. Med. Hist. , vol.3 , pp. 218-227
    • Major, R.H.1
  • 124
    • 0033566127 scopus 로고    scopus 로고
    • Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors
    • Mancini D.N., Singh S.M., Archer T.K., and Rodenhiser D.I. Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors. Oncogene 18 (1999) 4108-4119
    • (1999) Oncogene , vol.18 , pp. 4108-4119
    • Mancini, D.N.1    Singh, S.M.2    Archer, T.K.3    Rodenhiser, D.I.4
  • 125
    • 0025745050 scopus 로고
    • Comparative increases of lead and barium with age in human tooth enamel, rib and ulna
    • Manea-Krichten M., Patterson C., Miller G., Settle D., and Erel Y. Comparative increases of lead and barium with age in human tooth enamel, rib and ulna. Sci. Total Environ. 107 (1991) 179-203
    • (1991) Sci. Total Environ. , vol.107 , pp. 179-203
    • Manea-Krichten, M.1    Patterson, C.2    Miller, G.3    Settle, D.4    Erel, Y.5
  • 126
    • 0025835905 scopus 로고
    • Triggers and substrates of hippocampal synaptic plasticity
    • Massicotte G., and Baudry M. Triggers and substrates of hippocampal synaptic plasticity. Neurosci. Biobehav. Rev. 15 (1991) 415-423
    • (1991) Neurosci. Biobehav. Rev. , vol.15 , pp. 415-423
    • Massicotte, G.1    Baudry, M.2
  • 127
    • 0026588994 scopus 로고
    • Lead accumulation in the bones of aging male mice
    • Massie H.R., and Aiello V.R. Lead accumulation in the bones of aging male mice. Gerontology 38 (1992) 13-17
    • (1992) Gerontology , vol.38 , pp. 13-17
    • Massie, H.R.1    Aiello, V.R.2
  • 131
    • 0031040806 scopus 로고    scopus 로고
    • Mouse lymphoma cells destined to undergo apoptosis in response to thapsigargin treatment fail to generate a calcium-mediated grp78/grp94 stress response
    • McCormick T.S., McColl K.S., and Distelhorst C.W. Mouse lymphoma cells destined to undergo apoptosis in response to thapsigargin treatment fail to generate a calcium-mediated grp78/grp94 stress response. J. Biol. Chem. 272 (1997) 6087-6092
    • (1997) J. Biol. Chem. , vol.272 , pp. 6087-6092
    • McCormick, T.S.1    McColl, K.S.2    Distelhorst, C.W.3
  • 132
    • 0027506372 scopus 로고
    • The mechanism of expression of long-term enhancement of hippocampal synapses: current issues and theoretical implications
    • McNaughton B.L. The mechanism of expression of long-term enhancement of hippocampal synapses: current issues and theoretical implications. Annu. Rev. Physiol. 55 (1993) 375-396
    • (1993) Annu. Rev. Physiol. , vol.55 , pp. 375-396
    • McNaughton, B.L.1
  • 133
    • 33749005641 scopus 로고    scopus 로고
    • Blood lead below 0.48 micromol/L (10 microg/dL) and mortality among US adults
    • Menke A., Muntner P., Batuman V., Silbergeld E.K., and Guallar E. Blood lead below 0.48 micromol/L (10 microg/dL) and mortality among US adults. Circulation 114 (2006) 1388-1394
    • (2006) Circulation , vol.114 , pp. 1388-1394
    • Menke, A.1    Muntner, P.2    Batuman, V.3    Silbergeld, E.K.4    Guallar, E.5
  • 134
    • 0025365586 scopus 로고
    • Study of the Alzheimer's A4 precursor gene promoter region by genomic sequencing using Taq polymerase
    • Milici A., Salbaum J.M., and Beyereuther K. Study of the Alzheimer's A4 precursor gene promoter region by genomic sequencing using Taq polymerase. Biochem. Biophys. Res. Commun. 169 (1990) 46-50
    • (1990) Biochem. Biophys. Res. Commun. , vol.169 , pp. 46-50
    • Milici, A.1    Salbaum, J.M.2    Beyereuther, K.3
  • 135
    • 23244458855 scopus 로고    scopus 로고
    • Adult neurogenesis in the mammalian central nervous system
    • Ming G.L., and Song H. Adult neurogenesis in the mammalian central nervous system. Annu. Rev. Neurosci. 28 (2005) 223-250
    • (2005) Annu. Rev. Neurosci. , vol.28 , pp. 223-250
    • Ming, G.L.1    Song, H.2
  • 136
    • 0023837076 scopus 로고
    • Calcium efflux and neurotransmitter release from rat hippocampal synaptosomes exposed to lead
    • Minnema D.J., Michaelson I.A., and Cooper G.P. Calcium efflux and neurotransmitter release from rat hippocampal synaptosomes exposed to lead. Toxicol. Appl. Pharmacol. 92 (1988) 351-357
    • (1988) Toxicol. Appl. Pharmacol. , vol.92 , pp. 351-357
    • Minnema, D.J.1    Michaelson, I.A.2    Cooper, G.P.3
  • 137
    • 0034995425 scopus 로고    scopus 로고
    • Environmental lead-210 and bismuth-210 accrue selectively in the brain proteins in Alzheimer disease and brain lipids in Parkinson disease
    • Momcilovic B., Alkhatib H.A., Duerre J.A., Cooley M., Long W.M., Harris T.R., and Lykken G.I. Environmental lead-210 and bismuth-210 accrue selectively in the brain proteins in Alzheimer disease and brain lipids in Parkinson disease. Alzheimer Dis. Assoc. Disord. 15 (2001) 106-115
    • (2001) Alzheimer Dis. Assoc. Disord. , vol.15 , pp. 106-115
    • Momcilovic, B.1    Alkhatib, H.A.2    Duerre, J.A.3    Cooley, M.4    Long, W.M.5    Harris, T.R.6    Lykken, G.I.7
  • 138
    • 0034612062 scopus 로고    scopus 로고
    • Effects of chronic lead exposure on learning and reaction time in a visual discrimination task
    • Morgan R.E., Levitsky D.A., and Strupp B.J. Effects of chronic lead exposure on learning and reaction time in a visual discrimination task. Neurotoxicol. Teratol. 22 (2000) 337-345
    • (2000) Neurotoxicol. Teratol. , vol.22 , pp. 337-345
    • Morgan, R.E.1    Levitsky, D.A.2    Strupp, B.J.3
  • 139
    • 0034716887 scopus 로고    scopus 로고
    • Tripartite management of unfolded proteins in the endoplasmic reticulum
    • Mori K. Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 101 (2000) 451-454
    • (2000) Cell , vol.101 , pp. 451-454
    • Mori, K.1
  • 140
    • 0022650213 scopus 로고
    • Selective impairment of learning and blockade of long-term potentiation by an N-methyl-d-aspartate receptor antagonist, AP5
    • Morris R.G., Anderson E., Lynch G.S., and Baudry M. Selective impairment of learning and blockade of long-term potentiation by an N-methyl-d-aspartate receptor antagonist, AP5. Nature 319 (1986) 774-776
    • (1986) Nature , vol.319 , pp. 774-776
    • Morris, R.G.1    Anderson, E.2    Lynch, G.S.3    Baudry, M.4
  • 141
    • 0034093102 scopus 로고    scopus 로고
    • PCR amplification in bisulfite methylcytosine mapping in the GC-rich promoter region of amyloid precursor protein gene in autopsy human brain
    • Nagane Y., Utsugisawa K., and Tohgi H. PCR amplification in bisulfite methylcytosine mapping in the GC-rich promoter region of amyloid precursor protein gene in autopsy human brain. Brain Res. Brain Res. Protoc. 5 (2000) 167-171
    • (2000) Brain Res. Brain Res. Protoc. , vol.5 , pp. 167-171
    • Nagane, Y.1    Utsugisawa, K.2    Tohgi, H.3
  • 142
    • 1642442424 scopus 로고    scopus 로고
    • Microglia: neuroprotective and neurotrophic cells in the central nervous system
    • Nakajima K., and Kohsaka S. Microglia: neuroprotective and neurotrophic cells in the central nervous system. Curr. Drug Targets Cardiovasc. Haematol. Disord. 4 (2004) 65-84
    • (2004) Curr. Drug Targets Cardiovasc. Haematol. Disord. , vol.4 , pp. 65-84
    • Nakajima, K.1    Kohsaka, S.2
  • 143
    • 20444366189 scopus 로고    scopus 로고
    • 2+ exposure alters the lens alpha A-crystallin protein profile in vivo and induces cataract formation in lens organ culture
    • 2+ exposure alters the lens alpha A-crystallin protein profile in vivo and induces cataract formation in lens organ culture. Toxicology 212 (2005) 1-9
    • (2005) Toxicology , vol.212 , pp. 1-9
    • Neal, R.1    Aykin-Burns, N.2    Ercal, N.3    Zigler Jr., J.S.4
  • 144
    • 0034638256 scopus 로고    scopus 로고
    • N-Methyl-d-aspartate receptor subunit changes are associated with lead-induced deficits of long-term potentiation and spatial learning
    • Nihei M.K., Desmond N.L., McGlothan J.L., Kuhlmann A.C., and Guilarte T.R. N-Methyl-d-aspartate receptor subunit changes are associated with lead-induced deficits of long-term potentiation and spatial learning. Neuroscience 99 (2000) 233-242
    • (2000) Neuroscience , vol.99 , pp. 233-242
    • Nihei, M.K.1    Desmond, N.L.2    McGlothan, J.L.3    Kuhlmann, A.C.4    Guilarte, T.R.5
  • 145
    • 0016595355 scopus 로고
    • Neurofibrillary changes following childhood lead encephalopathy
    • Niklowitz W.J., and Mandybur T.I. Neurofibrillary changes following childhood lead encephalopathy. J. Neuropathol. Exp. Neurol. 34 (1975) 445-455
    • (1975) J. Neuropathol. Exp. Neurol. , vol.34 , pp. 445-455
    • Niklowitz, W.J.1    Mandybur, T.I.2
  • 146
    • 0033598996 scopus 로고    scopus 로고
    • A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response
    • Niwa M., Sidrauski C., Kaufman R.J., and Walter P. A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response. Cell 99 (1999) 691-702
    • (1999) Cell , vol.99 , pp. 691-702
    • Niwa, M.1    Sidrauski, C.2    Kaufman, R.J.3    Walter, P.4
  • 147
    • 0034694896 scopus 로고    scopus 로고
    • Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast
    • Okamura K., Kimata Y., Higashio H., Tsuru A., and Kohno K. Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast. Biochem. Biophys. Res. Commun. 279 (2000) 445-450
    • (2000) Biochem. Biophys. Res. Commun. , vol.279 , pp. 445-450
    • Okamura, K.1    Kimata, Y.2    Higashio, H.3    Tsuru, A.4    Kohno, K.5
  • 148
    • 0030426276 scopus 로고    scopus 로고
    • The sensitivity of N-methyl-d-aspartate receptors to lead inhibition is dependent on the receptor subunit composition
    • Omelchenko I.A., Nelson C.S., Marino J.L., and Allen C.N. The sensitivity of N-methyl-d-aspartate receptors to lead inhibition is dependent on the receptor subunit composition. J. Pharmacol. Exp. Ther. 278 (1996) 15-20
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 15-20
    • Omelchenko, I.A.1    Nelson, C.S.2    Marino, J.L.3    Allen, C.N.4
  • 149
    • 0030931723 scopus 로고    scopus 로고
    • Lead inhibition of N-methyl-d-aspartate receptors containing NR2A, NR2C and NR2D subunits
    • Omelchenko I.A., Nelson C.S., and Allen C.N. Lead inhibition of N-methyl-d-aspartate receptors containing NR2A, NR2C and NR2D subunits. J. Pharmacol. Exp. Ther. 282 (1997) 1458-1464
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 1458-1464
    • Omelchenko, I.A.1    Nelson, C.S.2    Allen, C.N.3
  • 150
    • 0028806228 scopus 로고
    • Dendritic alterations of cortical pyramidal neurons in postnatally lead-exposed kittens: a Golgi-Cox study
    • Patrick G.W., and Anderson W.J. Dendritic alterations of cortical pyramidal neurons in postnatally lead-exposed kittens: a Golgi-Cox study. Dev. Neurosci. 17 (1995) 219-229
    • (1995) Dev. Neurosci. , vol.17 , pp. 219-229
    • Patrick, G.W.1    Anderson, W.J.2
  • 152
    • 0041620549 scopus 로고    scopus 로고
    • Astrocyte-targeted expression of interleukin-6 protects the central nervous system during neuroglial degeneration induced by 6-aminonicotinamide
    • Penkowa M., Camats J., Hadberg H., Quintana A., Rojas S., Giralt M., Molinero A., Campbell I.L., and Hidalgo J. Astrocyte-targeted expression of interleukin-6 protects the central nervous system during neuroglial degeneration induced by 6-aminonicotinamide. J. Neurosci. Res. 73 (2003) 481-496
    • (2003) J. Neurosci. Res. , vol.73 , pp. 481-496
    • Penkowa, M.1    Camats, J.2    Hadberg, H.3    Quintana, A.4    Rojas, S.5    Giralt, M.6    Molinero, A.7    Campbell, I.L.8    Hidalgo, J.9
  • 154
    • 1542407681 scopus 로고    scopus 로고
    • Prevention of neuron and oligodendrocyte degeneration by interleukin-6 (IL-6) and IL-6 receptor/IL-6 fusion protein in organotypic hippocampal slices
    • Pizzi M., Sarnico I., Boroni F., Benarese M., Dreano M., Garotta G., Valerio A., and Spano P. Prevention of neuron and oligodendrocyte degeneration by interleukin-6 (IL-6) and IL-6 receptor/IL-6 fusion protein in organotypic hippocampal slices. Mol. Cell. Neurosci. 25 (2004) 301-311
    • (2004) Mol. Cell. Neurosci. , vol.25 , pp. 301-311
    • Pizzi, M.1    Sarnico, I.2    Boroni, F.3    Benarese, M.4    Dreano, M.5    Garotta, G.6    Valerio, A.7    Spano, P.8
  • 155
    • 0036803978 scopus 로고    scopus 로고
    • The prospective role of abnormal methyl metabolism in cadmium toxicity
    • Poirier L.A., and Vlasova T.I. The prospective role of abnormal methyl metabolism in cadmium toxicity. Environ. Health Perspect. 10 (2002) 793-795
    • (2002) Environ. Health Perspect. , vol.10 , pp. 793-795
    • Poirier, L.A.1    Vlasova, T.I.2
  • 156
    • 0026507460 scopus 로고
    • The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter
    • Pollwein P., Masters C., and Beyruther K. The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter. Nucleic Acids Res. 20 (1992) 63-68
    • (1992) Nucleic Acids Res. , vol.20 , pp. 63-68
    • Pollwein, P.1    Masters, C.2    Beyruther, K.3
  • 157
    • 0037811901 scopus 로고    scopus 로고
    • Fetal hypoxia, genetic risk, and schizophrenia
    • Preti A. Fetal hypoxia, genetic risk, and schizophrenia. Am. J. Psychiatry 160 (2003) 1186
    • (2003) Am. J. Psychiatry , vol.160 , pp. 1186
    • Preti, A.1
  • 158
    • 0037263626 scopus 로고    scopus 로고
    • Lead-induced endoplasmic reticulum (ER) stress responses in the nervous system
    • Qian Y.C., and Tiffany-Castiglioni E. Lead-induced endoplasmic reticulum (ER) stress responses in the nervous system. Neurochem. Res. 28 (2003) 153-162
    • (2003) Neurochem. Res. , vol.28 , pp. 153-162
    • Qian, Y.C.1    Tiffany-Castiglioni, E.2
  • 159
  • 162
    • 0035199528 scopus 로고    scopus 로고
    • Induction of 78 kD glucose-regulated protein (GRP78) expression and redox-regulated transcription factor activity by lead and mercury in C6 rat glioma cells
    • Qian Y.C., Falahatpisheh M.H., Zheng Y., Ramos K.S., and Tiffany-Castiglioni E. Induction of 78 kD glucose-regulated protein (GRP78) expression and redox-regulated transcription factor activity by lead and mercury in C6 rat glioma cells. Neurotox. Res. 3 (2001) 581-589
    • (2001) Neurotox. Res. , vol.3 , pp. 581-589
    • Qian, Y.C.1    Falahatpisheh, M.H.2    Zheng, Y.3    Ramos, K.S.4    Tiffany-Castiglioni, E.5
  • 163
    • 13844265748 scopus 로고    scopus 로고
    • GRP78 compartmentalized redistribution in Pb-treated glia: role of GRP78 in lead-induced oxidative stress
    • Qian Y.C., Zheng Y., Ramos K.S., and Tiffany-Castiglioni E. GRP78 compartmentalized redistribution in Pb-treated glia: role of GRP78 in lead-induced oxidative stress. Neurotoxicology 26 (2005) 267-275
    • (2005) Neurotoxicology , vol.26 , pp. 267-275
    • Qian, Y.C.1    Zheng, Y.2    Ramos, K.S.3    Tiffany-Castiglioni, E.4
  • 164
    • 34548774083 scopus 로고    scopus 로고
    • A 78-kDa glucose-regulated protein is involved in the decrease of interleukin-6 secretion by lead treatment from astrocytes
    • Qian Y.C., Zheng Y., Weber D., and Tiffany-Castiglioni E. A 78-kDa glucose-regulated protein is involved in the decrease of interleukin-6 secretion by lead treatment from astrocytes. Am. J. Physiol., Cell Physiol. 293 (2007) C897-C905
    • (2007) Am. J. Physiol., Cell Physiol. , vol.293
    • Qian, Y.C.1    Zheng, Y.2    Weber, D.3    Tiffany-Castiglioni, E.4
  • 165
    • 0033577830 scopus 로고    scopus 로고
    • Enhancer function and novel DNA binding protein activity in the near upstream betaAPP gene promoter
    • Querfurth H.W., Jiang J., Xia W., and Selkoe D.J. Enhancer function and novel DNA binding protein activity in the near upstream betaAPP gene promoter. Gene 232 (1999) 125-141
    • (1999) Gene , vol.232 , pp. 125-141
    • Querfurth, H.W.1    Jiang, J.2    Xia, W.3    Selkoe, D.J.4
  • 166
    • 0025777029 scopus 로고
    • Activation of the NMDA receptor: a correlate in the dentate gyrus field potential and its relationship to long-term potentiation and kindling
    • Racine R.J., Moore K.A., and Wicks S. Activation of the NMDA receptor: a correlate in the dentate gyrus field potential and its relationship to long-term potentiation and kindling. Brain Res. 556 (1991) 226-239
    • (1991) Brain Res. , vol.556 , pp. 226-239
    • Racine, R.J.1    Moore, K.A.2    Wicks, S.3
  • 168
    • 7744232493 scopus 로고    scopus 로고
    • Misfolded proteins, endoplasmic reticulum stress and neurodegeneration
    • Rao R.V., and Bredesen D.E. Misfolded proteins, endoplasmic reticulum stress and neurodegeneration. Curr. Opin. Cell Biol. 16 (2004) 653-662
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 653-662
    • Rao, R.V.1    Bredesen, D.E.2
  • 169
    • 0038080911 scopus 로고    scopus 로고
    • Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation
    • Reddy R.K., Mao C., Baumeister P., Austin R.C., Kaufman R.J., and Lee A.S. Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation. J. Biol. Chem. 278 (2003) 20915-20924
    • (2003) J. Biol. Chem. , vol.278 , pp. 20915-20924
    • Reddy, R.K.1    Mao, C.2    Baumeister, P.3    Austin, R.C.4    Kaufman, R.J.5    Lee, A.S.6
  • 170
    • 0142226999 scopus 로고    scopus 로고
    • Behavioral sensitization and long-term neurochemical alterations associated with the fungicide triadimefon
    • Reeves R., Thiruchelvam M., Richfield E.K., and Cory-Slechta D.A. Behavioral sensitization and long-term neurochemical alterations associated with the fungicide triadimefon. Pharmacol. Biochem. Behav. 76 (2003) 315-326
    • (2003) Pharmacol. Biochem. Behav. , vol.76 , pp. 315-326
    • Reeves, R.1    Thiruchelvam, M.2    Richfield, E.K.3    Cory-Slechta, D.A.4
  • 171
    • 0026048411 scopus 로고
    • Delayed expression of neurotoxicity: the problem of silent damage
    • Reuhl K.R. Delayed expression of neurotoxicity: the problem of silent damage. Neurotoxicology 12 (1991) 341-346
    • (1991) Neurotoxicology , vol.12 , pp. 341-346
    • Reuhl, K.R.1
  • 172
    • 33746654163 scopus 로고    scopus 로고
    • Restoration of long-term potentiation in middle-aged hippocampus after induction of brain-derived neurotrophic factor
    • Rex C.S., Lauterborn J.C., Lin C.Y., Kramar E.A., Rogers G.A., Gall C.M., and Lynch G. Restoration of long-term potentiation in middle-aged hippocampus after induction of brain-derived neurotrophic factor. J. Neurophysiol. 96 (2006) 677-685
    • (2006) J. Neurophysiol. , vol.96 , pp. 677-685
    • Rex, C.S.1    Lauterborn, J.C.2    Lin, C.Y.3    Kramar, E.A.4    Rogers, G.A.5    Gall, C.M.6    Lynch, G.7
  • 174
    • 33845864415 scopus 로고    scopus 로고
    • The late maintenance of hippocampal LTP: requirements, phases, 'synaptic tagging', 'late-associativity' and implications
    • Reymann K.G., and Frey J.U. The late maintenance of hippocampal LTP: requirements, phases, 'synaptic tagging', 'late-associativity' and implications. Neuropharmacology 52 (2007) 24-40
    • (2007) Neuropharmacology , vol.52 , pp. 24-40
    • Reymann, K.G.1    Frey, J.U.2
  • 175
    • 0024942011 scopus 로고
    • Delayed neurotoxicity in monkeys exposed developmentally to methylmercury
    • Rice D.C. Delayed neurotoxicity in monkeys exposed developmentally to methylmercury. Neurotoxicology 10 (1989) 645-650
    • (1989) Neurotoxicology , vol.10 , pp. 645-650
    • Rice, D.C.1
  • 176
    • 0030198019 scopus 로고    scopus 로고
    • Comparing the role of metabotropic glutamate receptors in long-term potentiation and in learning and memory
    • Riedel G., Wetzel W., and Reymann K.G. Comparing the role of metabotropic glutamate receptors in long-term potentiation and in learning and memory. Prog. Neuro-Psychopharmacol. Biol. Psychiatry 20 (1996) 761-789
    • (1996) Prog. Neuro-Psychopharmacol. Biol. Psychiatry , vol.20 , pp. 761-789
    • Riedel, G.1    Wetzel, W.2    Reymann, K.G.3
  • 177
    • 2142777413 scopus 로고
    • Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides
    • Robakis N.K., Ramakrishna N., Wolfe G., and Wisniewski H.M. Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides. Proc. Natl. Acad. Sci. U. S. A. 84 (1987) 4190-4194
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 4190-4194
    • Robakis, N.K.1    Ramakrishna, N.2    Wolfe, G.3    Wisniewski, H.M.4
  • 178
    • 0026500787 scopus 로고
    • Effect of MK-801 on the induction and subsequent decay of long-term potentiation in the unanesthetized rabbit hippocampal dentate gyrus
    • Robinson G.B., and Reed G.D. Effect of MK-801 on the induction and subsequent decay of long-term potentiation in the unanesthetized rabbit hippocampal dentate gyrus. Brain Res. 569 (1992) 78-85
    • (1992) Brain Res. , vol.569 , pp. 78-85
    • Robinson, G.B.1    Reed, G.D.2
  • 179
    • 0028169984 scopus 로고
    • The upstream promoter of the beta-amyloid precursor protein gene (APP) shows differential patterns of methylation in human brain
    • Rogaev E.I., Lukiw W.J., Lavrushina O., Rogaeva E.A., and St George-Hyslop P.H. The upstream promoter of the beta-amyloid precursor protein gene (APP) shows differential patterns of methylation in human brain. Genomics 22 (1994) 340-347
    • (1994) Genomics , vol.22 , pp. 340-347
    • Rogaev, E.I.1    Lukiw, W.J.2    Lavrushina, O.3    Rogaeva, E.A.4    St George-Hyslop, P.H.5
  • 183
    • 10344249905 scopus 로고    scopus 로고
    • Accumulated lead exposure and risk of age-related cataract in men
    • Schaumberg D.A., Mendes F., Balaram M., Dana M.R., Sparrow D., and Hu H. Accumulated lead exposure and risk of age-related cataract in men. JAMA 292 (2004) 2750-2754
    • (2004) JAMA , vol.292 , pp. 2750-2754
    • Schaumberg, D.A.1    Mendes, F.2    Balaram, M.3    Dana, M.R.4    Sparrow, D.5    Hu, H.6
  • 184
    • 7444239113 scopus 로고    scopus 로고
    • Inhibition of progenitor cell proliferation in the dentate gyrus of rats following post-weaning lead exposure
    • Schneider J.S., Anderson D.W., Wade T.V., Smith M.G., Leibrandt P., Zuck L., and Lidsky T.I. Inhibition of progenitor cell proliferation in the dentate gyrus of rats following post-weaning lead exposure. Neurotoxicology 26 (2005) 141-145
    • (2005) Neurotoxicology , vol.26 , pp. 141-145
    • Schneider, J.S.1    Anderson, D.W.2    Wade, T.V.3    Smith, M.G.4    Leibrandt, P.5    Zuck, L.6    Lidsky, T.I.7
  • 186
    • 7944233158 scopus 로고    scopus 로고
    • Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases
    • Selkoe D.J. Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Nat. Cell Biol. 6 (2004) 1054-1061
    • (2004) Nat. Cell Biol. , vol.6 , pp. 1054-1061
    • Selkoe, D.J.1
  • 187
    • 0022654027 scopus 로고
    • Isolation of low-molecular-weight proteins from amyloi4 plaque fibers in Alzheimer's disease
    • Selkoe D.J., Abraham C.R., Podlisny M.B., and Duffy L.K. Isolation of low-molecular-weight proteins from amyloi4 plaque fibers in Alzheimer's disease. J. Neurochem. 46 (1986) 1820-1834
    • (1986) J. Neurochem. , vol.46 , pp. 1820-1834
    • Selkoe, D.J.1    Abraham, C.R.2    Podlisny, M.B.3    Duffy, L.K.4
  • 188
    • 0025959437 scopus 로고
    • Reduction of glutamine synthetase activity in astroglia exposed in culture to low levels of inorganic lead
    • Sierra E.M., and Tiffany-Castiglioni E. Reduction of glutamine synthetase activity in astroglia exposed in culture to low levels of inorganic lead. Toxicology 65 (1991) 295-304
    • (1991) Toxicology , vol.65 , pp. 295-304
    • Sierra, E.M.1    Tiffany-Castiglioni, E.2
  • 189
    • 0344845177 scopus 로고    scopus 로고
    • Facilitative mechanisms of lead as a carcinogen
    • Silbergeld E.K. Facilitative mechanisms of lead as a carcinogen. Mutat. Res. 533 (2003) 121-133
    • (2003) Mutat. Res. , vol.533 , pp. 121-133
    • Silbergeld, E.K.1
  • 190
    • 1542393404 scopus 로고    scopus 로고
    • Reductions in blood lead overestimate reductions in brain lead following repeated succimer regimens in a rodent model of childhood lead exposure
    • Stangle D.E., Strawderman M.S., Smith D., Kuypers M., and Strupp B.J. Reductions in blood lead overestimate reductions in brain lead following repeated succimer regimens in a rodent model of childhood lead exposure. Environ. Health Perspect. 112 (2004) 302-308
    • (2004) Environ. Health Perspect. , vol.112 , pp. 302-308
    • Stangle, D.E.1    Strawderman, M.S.2    Smith, D.3    Kuypers, M.4    Strupp, B.J.5
  • 191
    • 0034117509 scopus 로고    scopus 로고
    • Job strain and anger expression predict early morning elevation in salivary cortisol
    • Steptoe A., Cropley M., Griffith J., and Kirschbaum C. Job strain and anger expression predict early morning elevation in salivary cortisol. Psychosom. Med. 62 (2000) 286-292
    • (2000) Psychosom. Med. , vol.62 , pp. 286-292
    • Steptoe, A.1    Cropley, M.2    Griffith, J.3    Kirschbaum, C.4
  • 194
    • 0034612066 scopus 로고    scopus 로고
    • Age-related impairment of long-term depression in area CA1 and dentate gyrus of rat hippocampus following developmental lead exposure in vitro
    • Sui L., Ge S.Y., Ruan D.Y., Chen J.T., Xu Y.Z., and Wang M. Age-related impairment of long-term depression in area CA1 and dentate gyrus of rat hippocampus following developmental lead exposure in vitro. Neurotoxicol. Teratol. 22 (2000) 381-387
    • (2000) Neurotoxicol. Teratol. , vol.22 , pp. 381-387
    • Sui, L.1    Ge, S.Y.2    Ruan, D.Y.3    Chen, J.T.4    Xu, Y.Z.5    Wang, M.6
  • 195
    • 0028322017 scopus 로고
    • An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
    • Suzuki N., Cheung T.T., Cai X.D., Odaka A., Otvos Jr. L., Eckman C., Golde T.E., and Younkin S.G. An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science 264 (1994) 1336-1340
    • (1994) Science , vol.264 , pp. 1336-1340
    • Suzuki, N.1    Cheung, T.T.2    Cai, X.D.3    Odaka, A.4    Otvos Jr., L.5    Eckman, C.6    Golde, T.E.7    Younkin, S.G.8
  • 196
    • 0030890718 scopus 로고    scopus 로고
    • Gp130 and the interleukin-6 family of cytokines
    • Taga T., and Kishimoto T. Gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol. 15 (1997) 797-819
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 797-819
    • Taga, T.1    Kishimoto, T.2
  • 197
    • 0037960155 scopus 로고    scopus 로고
    • Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation
    • Takiguchi M., Achanzar W.E., Qu W., Li G., and Waalkes M.P. Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation. Exp. Cell Res. 286 (2003) 355-365
    • (2003) Exp. Cell Res. , vol.286 , pp. 355-365
    • Takiguchi, M.1    Achanzar, W.E.2    Qu, W.3    Li, G.4    Waalkes, M.P.5
  • 198
    • 0029899315 scopus 로고    scopus 로고
    • Lead cytotoxicity in primary cultured rat astrocytes and Schwann cells
    • Tang H.W., Yan H.L., Hu X.H., Liang Y.X., and Shen X.Y. Lead cytotoxicity in primary cultured rat astrocytes and Schwann cells. J. Appl. Toxicol. 16 (1996) 187-196
    • (1996) J. Appl. Toxicol. , vol.16 , pp. 187-196
    • Tang, H.W.1    Yan, H.L.2    Hu, X.H.3    Liang, Y.X.4    Shen, X.Y.5
  • 200
    • 0034992436 scopus 로고    scopus 로고
    • Postnatal inorganic lead exposure decreases the number of spontaneously active midbrain dopamine neurons in the rat
    • Tavakoli-Nezhad M., Barron A.J., and Pitts D.K. Postnatal inorganic lead exposure decreases the number of spontaneously active midbrain dopamine neurons in the rat. Neurotoxicology 22 (2001) 259-269
    • (2001) Neurotoxicology , vol.22 , pp. 259-269
    • Tavakoli-Nezhad, M.1    Barron, A.J.2    Pitts, D.K.3
  • 202
    • 0036778511 scopus 로고    scopus 로고
    • Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype
    • Thiruchelvam M., Richfield E.K., Goodman B.M., Baggs R.B., and Cory-Slechta D.A. Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype. Neurotoxicology 23 (2002) 621-633
    • (2002) Neurotoxicology , vol.23 , pp. 621-633
    • Thiruchelvam, M.1    Richfield, E.K.2    Goodman, B.M.3    Baggs, R.B.4    Cory-Slechta, D.A.5
  • 204
    • 33645371566 scopus 로고    scopus 로고
    • Cell-type-specific responses of the nervous system to lead
    • Tiffany-Castiglioni E. (Ed), Humana Press, Totowa, NJ
    • Tiffany-Castiglioni E., and Qian Y.C. Cell-type-specific responses of the nervous system to lead. In: Tiffany-Castiglioni E. (Ed). In Vitro Neurotoxicology: Principles and Challenges (2004), Humana Press, Totowa, NJ 151-186
    • (2004) In Vitro Neurotoxicology: Principles and Challenges , pp. 151-186
    • Tiffany-Castiglioni, E.1    Qian, Y.C.2
  • 205
    • 35649022439 scopus 로고    scopus 로고
    • Chapter 26. Astroglia and lead neurotoxicity
    • Aschner M., and Costa L.G. (Eds), CRC Press, Boca Raton
    • Tiffany-Castiglioni E., and Qian Y.C. Chapter 26. Astroglia and lead neurotoxicity. In: Aschner M., and Costa L.G. (Eds). The Role of Glia in Neurotoxicity (2005), CRC Press, Boca Raton 417-437
    • (2005) The Role of Glia in Neurotoxicity , pp. 417-437
    • Tiffany-Castiglioni, E.1    Qian, Y.C.2
  • 206
    • 0023615311 scopus 로고
    • Effects of lead treatment on intracellular iron and copper concentrations in cultured astroglia
    • Tiffany-Castiglioni E., Zmudzki J., Wu J.N., and Bratton G.R. Effects of lead treatment on intracellular iron and copper concentrations in cultured astroglia. Metab. Brain Dis. 2 (1987) 61-79
    • (1987) Metab. Brain Dis. , vol.2 , pp. 61-79
    • Tiffany-Castiglioni, E.1    Zmudzki, J.2    Wu, J.N.3    Bratton, G.R.4
  • 210
    • 33747161934 scopus 로고    scopus 로고
    • Chapter 22. In vitro models for testing organophosphate-induced neurotoxicity and remediation
    • Gupta R.C. (Ed), Elsevier Academic Press, Amsterdam
    • Tiffany-Castiglioni E., Venkatraj V., Qian Y.C., and Wild J.R. Chapter 22. In vitro models for testing organophosphate-induced neurotoxicity and remediation. In: Gupta R.C. (Ed). Toxicology of Organophosphate and Carbamate Compounds (2006), Elsevier Academic Press, Amsterdam 315-337
    • (2006) Toxicology of Organophosphate and Carbamate Compounds , pp. 315-337
    • Tiffany-Castiglioni, E.1    Venkatraj, V.2    Qian, Y.C.3    Wild, J.R.4
  • 211
    • 0033052929 scopus 로고    scopus 로고
    • Reduction with age in methylcytosine in the promoter region - 224 approximately - 101 of the amyloid precursor protein gene in autopsy human cortex
    • Tohgi H., Utsugisawa K., Nagane Y., Yoshimura M., Genda Y., and Ukitsu M. Reduction with age in methylcytosine in the promoter region - 224 approximately - 101 of the amyloid precursor protein gene in autopsy human cortex. Brain Res. Mol. Brain Res. 70 (1999) 288-292
    • (1999) Brain Res. Mol. Brain Res. , vol.70 , pp. 288-292
    • Tohgi, H.1    Utsugisawa, K.2    Nagane, Y.3    Yoshimura, M.4    Genda, Y.5    Ukitsu, M.6
  • 212
    • 0026454799 scopus 로고
    • Developmental change of the inhibition by lead of NMDA-activated currents in cultured hippocampal neurons
    • Ujihara H., and Albuquerque E.X. Developmental change of the inhibition by lead of NMDA-activated currents in cultured hippocampal neurons. J. Pharmacol. Exp. Ther. 263 (1992) 868-875
    • (1992) J. Pharmacol. Exp. Ther. , vol.263 , pp. 868-875
    • Ujihara, H.1    Albuquerque, E.X.2
  • 213
    • 35648932218 scopus 로고    scopus 로고
    • U.S. Environmental Protection Agency (US EPA) 1977, Air quality criteria for lead. Research Triangle Park, NC: Health Effects Research Laboratory, Criteria and Special Studies Office, EPA report n. EPA-600/877-017. Available from: NTIS, Springfield, VA; PB-280411.
  • 214
    • 35648968913 scopus 로고    scopus 로고
    • U.S. Environmental Protection Agency, 1986, Air quality criteria for lead. Research Triangle Park, NC: Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office; EPA report no. EPA-600/8-83/028aF-dF. 4v. Available from: NTIS, Springfield, VA; PB87-142378.
  • 215
    • 35648955384 scopus 로고    scopus 로고
    • U.S. Environmental Protection Agency, 2006. Air Quality Criteria for Lead, Volume I and II of II. Research Triangle Park, NC: National Center for Environmental Assessment - RTP Office. Available at: http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=15882.
  • 216
    • 0028337093 scopus 로고
    • Birth weight and adult health outcomes in a biethnic population in the USA
    • Valdez R., Athens M.A., Thompson G.H., Bradshaw B.S., and Stern M.P. Birth weight and adult health outcomes in a biethnic population in the USA. Diabetologia 37 (1994) 624-631
    • (1994) Diabetologia , vol.37 , pp. 624-631
    • Valdez, R.1    Athens, M.A.2    Thompson, G.H.3    Bradshaw, B.S.4    Stern, M.P.5
  • 217
    • 0036600915 scopus 로고    scopus 로고
    • Pathogenesis of lead-induced hypertension: role of oxidative stress
    • Vaziri N.D. Pathogenesis of lead-induced hypertension: role of oxidative stress. J. Hypertens., Suppl. 20 (2002) S15-S20
    • (2002) J. Hypertens., Suppl. , vol.20
    • Vaziri, N.D.1
  • 218
    • 33947303852 scopus 로고    scopus 로고
    • Environmental lead exposure during early life alters granule cell neurogenesis and morphology in the hippocampus of young adult rats
    • Verina T., Rohde C.A., and Guilarte T.R. Environmental lead exposure during early life alters granule cell neurogenesis and morphology in the hippocampus of young adult rats. Neuroscience 145 (2007) 1037-1047
    • (2007) Neuroscience , vol.145 , pp. 1037-1047
    • Verina, T.1    Rohde, C.A.2    Guilarte, T.R.3
  • 219
    • 24944459046 scopus 로고    scopus 로고
    • Interactions of chronic lead exposure and intermittent stress: consequences for brain catecholamine systems and associated behaviors and HPA axis function
    • Virgolini M.B., Chen K., Weston D.D., Bauter M.R., and Cory-Slechta D.A. Interactions of chronic lead exposure and intermittent stress: consequences for brain catecholamine systems and associated behaviors and HPA axis function. Toxicol. Sci. 87 (2005) 469-482
    • (2005) Toxicol. Sci. , vol.87 , pp. 469-482
    • Virgolini, M.B.1    Chen, K.2    Weston, D.D.3    Bauter, M.R.4    Cory-Slechta, D.A.5
  • 220
    • 28544450892 scopus 로고    scopus 로고
    • Permanent alterations in stress responsivity in female offspring subjected to combined maternal lead exposure and/or stress
    • Virgolini M.B., Bauter M.R., Weston D.D., and Cory-Slechta D.A. Permanent alterations in stress responsivity in female offspring subjected to combined maternal lead exposure and/or stress. Neurotoxicology 27 (2006) 11-21
    • (2006) Neurotoxicology , vol.27 , pp. 11-21
    • Virgolini, M.B.1    Bauter, M.R.2    Weston, D.D.3    Cory-Slechta, D.A.4
  • 221
    • 0025003140 scopus 로고
    • Influence of chronic lead exposure on hormone levels in developing rats
    • Vyskocil A., Fiala Z., Ettlerova E., and Tenjnorova I. Influence of chronic lead exposure on hormone levels in developing rats. J. Appl. Toxicol. 10 (1990) 301-302
    • (1990) J. Appl. Toxicol. , vol.10 , pp. 301-302
    • Vyskocil, A.1    Fiala, Z.2    Ettlerova, E.3    Tenjnorova, I.4
  • 226
    • 0033520987 scopus 로고    scopus 로고
    • Posttranslational quality control: folding, refolding, and degrading proteins
    • Wickner S., Maurizi M.R., and Gottesman S. Posttranslational quality control: folding, refolding, and degrading proteins. Science 286 (1999) 1888-1893
    • (1999) Science , vol.286 , pp. 1888-1893
    • Wickner, S.1    Maurizi, M.R.2    Gottesman, S.3
  • 227
    • 0030952217 scopus 로고    scopus 로고
    • Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42
    • Wild-Bode C., Yamazaki T., Capell A., Leimer U., Steiner H., Ihara Y., and Haass C. Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42. J. Biol. Chem. 272 (1997) 16085-16088
    • (1997) J. Biol. Chem. , vol.272 , pp. 16085-16088
    • Wild-Bode, C.1    Yamazaki, T.2    Capell, A.3    Leimer, U.4    Steiner, H.5    Ihara, Y.6    Haass, C.7
  • 229
    • 0022535099 scopus 로고
    • Specific inhibition of myelination by lead in vitro; comparison with arsenic, thallium, and mercury
    • Windebank A.J. Specific inhibition of myelination by lead in vitro; comparison with arsenic, thallium, and mercury. Exp. Neurol. 94 (1986) 203-212
    • (1986) Exp. Neurol. , vol.94 , pp. 203-212
    • Windebank, A.J.1
  • 230
    • 0141592508 scopus 로고    scopus 로고
    • Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation
    • Wong W.K., Chen K., and Shih J.C. Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation. J. Biol. Chem. 278 (2003) 36227-36235
    • (2003) J. Biol. Chem. , vol.278 , pp. 36227-36235
    • Wong, W.K.1    Chen, K.2    Shih, J.C.3
  • 231
    • 0032475957 scopus 로고    scopus 로고
    • The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion
    • Yang Y., Turner R.S., and Gaut J.R. The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion. J. Biol. Chem. 273 (1998) 25552-25555
    • (1998) J. Biol. Chem. , vol.273 , pp. 25552-25555
    • Yang, Y.1    Turner, R.S.2    Gaut, J.R.3
  • 232
    • 0031708579 scopus 로고    scopus 로고
    • Birth weight, adult weight, and girth as predictors of the metabolic syndrome in postmenopausal women: the Rancho Bernardo Study
    • Yarbrough D.E., Barrett-Connor E., Kritz-Silverstein D., and Wingard D.L. Birth weight, adult weight, and girth as predictors of the metabolic syndrome in postmenopausal women: the Rancho Bernardo Study. Diabetes Care 21 (1998) 1652-1658
    • (1998) Diabetes Care , vol.21 , pp. 1652-1658
    • Yarbrough, D.E.1    Barrett-Connor, E.2    Kritz-Silverstein, D.3    Wingard, D.L.4
  • 233
    • 0033015485 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis
    • Yu Z., Luo H., Fu W., and Mattson M.P. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp. Neurol. 155 (1999) 302-314
    • (1999) Exp. Neurol. , vol.155 , pp. 302-314
    • Yu, Z.1    Luo, H.2    Fu, W.3    Mattson, M.P.4
  • 234
    • 31844433942 scopus 로고    scopus 로고
    • Environmental risk factors and the developmental basis for Alzheimer's disease
    • Zawia N.H., and Basha M.R. Environmental risk factors and the developmental basis for Alzheimer's disease. Rev. Neurosci. 16 (2005) 325-337
    • (2005) Rev. Neurosci. , vol.16 , pp. 325-337
    • Zawia, N.H.1    Basha, M.R.2
  • 235
    • 0032053686 scopus 로고    scopus 로고
    • Involvement of cytokines in normal CNS development and neurological diseases: recent progress and perspectives
    • Zhao B., and Schwartz J.P. Involvement of cytokines in normal CNS development and neurological diseases: recent progress and perspectives. J. Neurosci. Res. 52 (1998) 7-16
    • (1998) J. Neurosci. Res. , vol.52 , pp. 7-16
    • Zhao, B.1    Schwartz, J.P.2
  • 236
    • 2942755868 scopus 로고    scopus 로고
    • Signaling the unfolded protein response from the endoplasmic reticulum
    • Zhang K., and Kaufman R.J. Signaling the unfolded protein response from the endoplasmic reticulum. J. Biol. Chem. 279 (2004) 25935-25938
    • (2004) J. Biol. Chem. , vol.279 , pp. 25935-25938
    • Zhang, K.1    Kaufman, R.J.2
  • 237
    • 0036203759 scopus 로고    scopus 로고
    • Effect of developmental lead exposure on the expression of specific NMDA receptor subunit mRNAs in the hippocampus of neonatal rats by digoxigenin-labeled in situ hybridization histochemistry
    • Zhang X.Y., Liu A.P., Ruan D.Y., and Liu J. Effect of developmental lead exposure on the expression of specific NMDA receptor subunit mRNAs in the hippocampus of neonatal rats by digoxigenin-labeled in situ hybridization histochemistry. Neurotoxicol. Teratol. 24 (2005) 149-160
    • (2005) Neurotoxicol. Teratol. , vol.24 , pp. 149-160
    • Zhang, X.Y.1    Liu, A.P.2    Ruan, D.Y.3    Liu, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.