-
1
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
Hardy J., and Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297 (2002) 353-356
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
2
-
-
1442264828
-
Take five BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation
-
Haass C. Take five BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation. EMBO J. 23 (2004) 483-488
-
(2004)
EMBO J.
, vol.23
, pp. 483-488
-
-
Haass, C.1
-
3
-
-
0035921427
-
The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein
-
Cupers P., Bentahir M., Craessaerts K., Orlans I., Vanderstichele H., Saftig P., De Strooper B., and Annaert W. The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein. J. Cell Biol. 154 (2001) 731-740
-
(2001)
J. Cell Biol.
, vol.154
, pp. 731-740
-
-
Cupers, P.1
Bentahir, M.2
Craessaerts, K.3
Orlans, I.4
Vanderstichele, H.5
Saftig, P.6
De Strooper, B.7
Annaert, W.8
-
4
-
-
0032720496
-
Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neurons
-
Annaert W.G., Levesque L., Craessaerts K., Dierinck I., Snellings G., Westaway D., George-Hyslop P.S., Cordell B., Fraser P., and De Strooper B. Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neurons. J. Cell Biol. 147 (1999) 277-294
-
(1999)
J. Cell Biol.
, vol.147
, pp. 277-294
-
-
Annaert, W.G.1
Levesque, L.2
Craessaerts, K.3
Dierinck, I.4
Snellings, G.5
Westaway, D.6
George-Hyslop, P.S.7
Cordell, B.8
Fraser, P.9
De Strooper, B.10
-
5
-
-
0034610743
-
Caspase-12 mediated endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., and Yuan J. Caspase-12 mediated endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403 (2000) 98-103
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
6
-
-
0035170334
-
Dysregulation of cellular calcium homeostasis in Alzheimer's disease: bad genes and bad habits
-
Mattson M.P., and Chan S.L. Dysregulation of cellular calcium homeostasis in Alzheimer's disease: bad genes and bad habits. J. Mol. Neurosci. 17 (2001) 205-224
-
(2001)
J. Mol. Neurosci.
, vol.17
, pp. 205-224
-
-
Mattson, M.P.1
Chan, S.L.2
-
7
-
-
0028214450
-
Analysis of molecular masses and oligomeric states of protein complexes by blue native electrophoresis and isolation of membrane protein complexes by two-dimensional native electrophoresis
-
Schagger H., Cramer W.A., and von Jagow G. Analysis of molecular masses and oligomeric states of protein complexes by blue native electrophoresis and isolation of membrane protein complexes by two-dimensional native electrophoresis. Anal. Biochem. 217 (1994) 220-230
-
(1994)
Anal. Biochem.
, vol.217
, pp. 220-230
-
-
Schagger, H.1
Cramer, W.A.2
von Jagow, G.3
-
8
-
-
0041589436
-
Partial purification and characterization of γ-secretase from post-mortem human brain
-
Farmery M.R., Tjernberg L.O., Pursglove S.E., Bergman A., Winblad B., and Näslund J. Partial purification and characterization of γ-secretase from post-mortem human brain. J. Biol. Chem. 278 (2003) 24277-24284
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 24277-24284
-
-
Farmery, M.R.1
Tjernberg, L.O.2
Pursglove, S.E.3
Bergman, A.4
Winblad, B.5
Näslund, J.6
-
9
-
-
0028339518
-
Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus
-
Hammond C., and Helenius A. Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus. J. Cell Biol. 126 (1994) 41-52
-
(1994)
J. Cell Biol.
, vol.126
, pp. 41-52
-
-
Hammond, C.1
Helenius, A.2
-
10
-
-
0020144729
-
Nycodenz: a new nonionic iodinated gradient medium
-
Rickwood D., Ford T., and Graham J. Nycodenz: a new nonionic iodinated gradient medium. Anal. Biochem. 123 (1982) 23-31
-
(1982)
Anal. Biochem.
, vol.123
, pp. 23-31
-
-
Rickwood, D.1
Ford, T.2
Graham, J.3
-
11
-
-
0037431082
-
Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex
-
De Strooper B. Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex. Neuron 38 (2003) 9-12
-
(2003)
Neuron
, vol.38
, pp. 9-12
-
-
De Strooper, B.1
-
12
-
-
0141733241
-
Assembly of the gamma-secretase complex involves early formation of an intermediate subcomplex of Aph-1 and nicastrin
-
LaVoie M.J., Fraering P.C., Ostaszewski B.L., Ye W., Kimberly T., Wolfe M.S., and Selkoe D.J. Assembly of the gamma-secretase complex involves early formation of an intermediate subcomplex of Aph-1 and nicastrin. J. Biol. Chem. 278 (2003) 37213-37222
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37213-37222
-
-
LaVoie, M.J.1
Fraering, P.C.2
Ostaszewski, B.L.3
Ye, W.4
Kimberly, T.5
Wolfe, M.S.6
Selkoe, D.J.7
-
13
-
-
0035875665
-
The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum
-
Yamamoto K., Fujii R., Toyofuku Y., Saito T., Koseki H., Hsu V.W., and Aoe T. The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum. EMBO J. 20 (2001) 3082-3091
-
(2001)
EMBO J.
, vol.20
, pp. 3082-3091
-
-
Yamamoto, K.1
Fujii, R.2
Toyofuku, Y.3
Saito, T.4
Koseki, H.5
Hsu, V.W.6
Aoe, T.7
-
14
-
-
0035910471
-
Increased production of beta-amyloid and vulnerability to endoplasmic reticulum stress by an aberrant spliced form of presenilin 2
-
Sato N., Imaizumi K., Manabe T., Taguchi M., Hitomi J., Katayama T., Yoneda T., Morihara T., Yasuda Y., Takagi T., Kudo T., Tsuda T., Itoyama Y., Makifuchi T., Fraser P.E., George-Hyslop P.St., and Tohyama M. Increased production of beta-amyloid and vulnerability to endoplasmic reticulum stress by an aberrant spliced form of presenilin 2. J. Biol. Chem. 276 (2001) 2108-2114
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2108-2114
-
-
Sato, N.1
Imaizumi, K.2
Manabe, T.3
Taguchi, M.4
Hitomi, J.5
Katayama, T.6
Yoneda, T.7
Morihara, T.8
Yasuda, Y.9
Takagi, T.10
Kudo, T.11
Tsuda, T.12
Itoyama, Y.13
Makifuchi, T.14
Fraser, P.E.15
George-Hyslop, P.St.16
Tohyama, M.17
-
15
-
-
0033258544
-
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
-
Katayama T., Imaizumi K., Sato N., Miyoshi K., Kudo T., Hitomi J., Morihara T., Yoneda T., Gomi F., Mori Y., Nakano Y., Takeda J., Tsuda T., Itoyama Y., Murayama O., Takashima A., George-Hyslop P.St., Takada M., and Tohyama M. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat. Cell Biol. 1 (1999) 479-485
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 479-485
-
-
Katayama, T.1
Imaizumi, K.2
Sato, N.3
Miyoshi, K.4
Kudo, T.5
Hitomi, J.6
Morihara, T.7
Yoneda, T.8
Gomi, F.9
Mori, Y.10
Nakano, Y.11
Takeda, J.12
Tsuda, T.13
Itoyama, Y.14
Murayama, O.15
Takashima, A.16
George-Hyslop, P.St.17
Takada, M.18
Tohyama, M.19
|