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Volumn 52, Issue 1, 1998, Pages 7-16

Involvement of cytokines in normal CNS development and neurological diseases: Recent progress and perspectives

Author keywords

Alzheimer's disease; Inflammation; Multiple sclerosis; Stroke; Transgenic mice

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 3; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 0032053686     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19980401)52:1<7::AID-JNR2>3.0.CO;2-I     Document Type: Short Survey
Times cited : (194)

References (129)
  • 1
    • 2642671249 scopus 로고    scopus 로고
    • Alzheimer's disease and microglia
    • Akiyama H (1997): Alzheimer's disease and microglia. Dementia 11:378-387.
    • (1997) Dementia , vol.11 , pp. 378-387
    • Akiyama, H.1
  • 2
    • 0029021217 scopus 로고
    • Do nonsteroidal anti-inflammatory drugs decrease the risk for Alzheimer's disease? The Rotterdam study
    • Andersen K, Launer LJ, Ott A, Hoes AW, Breteln MM, Hofman A (1995): Do nonsteroidal anti-inflammatory drugs decrease the risk for Alzheimer's disease? The Rotterdam study. Neurology 45:1441-1445.
    • (1995) Neurology , vol.45 , pp. 1441-1445
    • Andersen, K.1    Launer, L.J.2    Ott, A.3    Hoes, A.W.4    Breteln, M.M.5    Hofman, A.6
  • 3
    • 0027389388 scopus 로고
    • Trophic effects of interleukin-4, -7 and -8 on hippocampal neuronal cultures: Potential involvement of glial-derived factors
    • Araujo DM, Cotman CW (1993): Trophic effects of interleukin-4, -7 and -8 on hippocampal neuronal cultures: Potential involvement of glial-derived factors. Brain Res 600:49-55.
    • (1993) Brain Res , vol.600 , pp. 49-55
    • Araujo, D.M.1    Cotman, C.W.2
  • 4
    • 0028141540 scopus 로고
    • Induction of immune system mediators in the hippocampal formation in Alzheimer's and Parkinson's diseases: Selective effects on specific interleukins and interleukin receptors
    • Araujo DM, Lapchak PA (1994): Induction of immune system mediators in the hippocampal formation in Alzheimer's and Parkinson's diseases: Selective effects on specific interleukins and interleukin receptors. Neurosci 61:745-754.
    • (1994) Neurosci , vol.61 , pp. 745-754
    • Araujo, D.M.1    Lapchak, P.A.2
  • 6
    • 0030152374 scopus 로고    scopus 로고
    • Serum cytokine concentrations in patients with schizophrenia
    • Baker I, Masserano J, Wyatt RJ (1996): Serum cytokine concentrations in patients with schizophrenia. Schizophr Res 20:199-203.
    • (1996) Schizophr Res , vol.20 , pp. 199-203
    • Baker, I.1    Masserano, J.2    Wyatt, R.J.3
  • 7
    • 0027533631 scopus 로고
    • Interleukin-1 binding sites on astrocytes
    • Ban EM, Sarlieve LL, Haour FG (1993): Interleukin-1 binding sites on astrocytes. Neuroscience 52:725-733.
    • (1993) Neuroscience , vol.52 , pp. 725-733
    • Ban, E.M.1    Sarlieve, L.L.2    Haour, F.G.3
  • 8
    • 0030610645 scopus 로고    scopus 로고
    • Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E
    • Barger SW, Harmon AD (1997): Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature 388:878-881.
    • (1997) Nature , vol.388 , pp. 878-881
    • Barger, S.W.1    Harmon, A.D.2
  • 9
    • 0030957196 scopus 로고    scopus 로고
    • Isoform-specific modulation by apolipoprotein E of the activities of secreted β-amyloid precursor protein
    • Barger SW, Mattson MP (1997): Isoform-specific modulation by apolipoprotein E of the activities of secreted β-amyloid precursor protein. J Neurochem 69:60-67.
    • (1997) J Neurochem , vol.69 , pp. 60-67
    • Barger, S.W.1    Mattson, M.P.2
  • 12
    • 0027207998 scopus 로고
    • Cytokines in neuronal cell types
    • Bartfai T, Schultzberg M (1993): Cytokines in neuronal cell types. Neurochem Int 22:435-444.
    • (1993) Neurochem Int , vol.22 , pp. 435-444
    • Bartfai, T.1    Schultzberg, M.2
  • 13
    • 0027332670 scopus 로고
    • Interleukin 1-β inhibits synaptic strength and long-term potentiation in the rat CA1 hippocampus
    • Bellinger FP, Madamba S, Siggins GR (1993): Interleukin 1-β inhibits synaptic strength and long-term potentiation in the rat CA1 hippocampus. Brain Res 628:227-234.
    • (1993) Brain Res , vol.628 , pp. 227-234
    • Bellinger, F.P.1    Madamba, S.2    Siggins, G.R.3
  • 14
    • 0028843876 scopus 로고
    • Reduced long-term potentiation in the dentate gyrus of transgenic mice with cerebral overexpression of interleukin-6
    • Bellinger FP, Madamba SG, Campbell IL, Siggins GR (1995): Reduced long-term potentiation in the dentate gyrus of transgenic mice with cerebral overexpression of interleukin-6. Neurosci Lett 198:95-98.
    • (1995) Neurosci Lett , vol.198 , pp. 95-98
    • Bellinger, F.P.1    Madamba, S.G.2    Campbell, I.L.3    Siggins, G.R.4
  • 15
    • 0026638409 scopus 로고
    • Inflammatory cytokines within the central nervous system: Sources, function, and mechanism of action
    • Benveniste EN (1992): Inflammatory cytokines within the central nervous system: Sources, function, and mechanism of action. Am J Physiol 263:C1-C16.
    • (1992) Am J Physiol , vol.263
    • Benveniste, E.N.1
  • 16
    • 0029417080 scopus 로고
    • Interleukin-1β and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients
    • Blum-Degen D, Muller T, Kuhn W, Gerlach M, Przuntek H, Riederer P (1995): Interleukin-1β and interleukin-6 are elevated in the cerebrospinal fluid of Alzheimer's and de novo Parkinson's disease patients. Neurosci Lett 202:17-20.
    • (1995) Neurosci Lett , vol.202 , pp. 17-20
    • Blum-Degen, D.1    Muller, T.2    Kuhn, W.3    Gerlach, M.4    Przuntek, H.5    Riederer, P.6
  • 18
    • 0030987180 scopus 로고    scopus 로고
    • Biology of TGF-β in knockout and transgenic mouse models
    • Böttinger EP, Letterio JJ, Roberts AB (1997): Biology of TGF-β in knockout and transgenic mouse models. Kidney Int 51:1355-1360.
    • (1997) Kidney Int , vol.51 , pp. 1355-1360
    • Böttinger, E.P.1    Letterio, J.J.2    Roberts, A.B.3
  • 19
    • 0023889666 scopus 로고
    • Interleukin-1 immunoreactive innervation of the human hypothalamus
    • Breder CD, Dinarello CA, Saper CB (1988): Interleukin-1 immunoreactive innervation of the human hypothalamus. Science 240:321-324.
    • (1988) Science , vol.240 , pp. 321-324
    • Breder, C.D.1    Dinarello, C.A.2    Saper, C.B.3
  • 20
    • 0030000385 scopus 로고    scopus 로고
    • The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease
    • Breitner JCS (1996): The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease. Annu Rev Med 47:401-411.
    • (1996) Annu Rev Med , vol.47 , pp. 401-411
    • Breitner, J.C.S.1
  • 22
    • 0028866623 scopus 로고
    • Evolution of neuropathologic abnormalities associated with blood-brain barrier breakdown in transgenic mice expressing interleukin-6 in astrocytes
    • Brett FM, Mizisin AP, Powell HC, Campbell IL (1995): Evolution of neuropathologic abnormalities associated with blood-brain barrier breakdown in transgenic mice expressing interleukin-6 in astrocytes. J Neuropathol Exp Neurol 54:766-775.
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 766-775
    • Brett, F.M.1    Mizisin, A.P.2    Powell, H.C.3    Campbell, I.L.4
  • 24
    • 0028345963 scopus 로고
    • Cerebral expression of multiple cytokine genes in mice with lymphocytic choriomeningitis
    • Campbell IL, Hobbs MV, Kemper P, Oldstone MBA (1994): Cerebral expression of multiple cytokine genes in mice with lymphocytic choriomeningitis. J Immunol 152:716-723.
    • (1994) J Immunol , vol.152 , pp. 716-723
    • Campbell, I.L.1    Hobbs, M.V.2    Kemper, P.3    Oldstone, M.B.A.4
  • 25
    • 0028598750 scopus 로고
    • Reactive gliosis as a consequence of interleukin-6 expression in the brain: Studies in transgenic mice
    • Chiang C-S, Stalder A, Samimi A, Campbell IL (1994): Reactive gliosis as a consequence of interleukin-6 expression in the brain: Studies in transgenic mice. Dev Neurosci 16:212-221.
    • (1994) Dev Neurosci , vol.16 , pp. 212-221
    • Chiang, C.-S.1    Stalder, A.2    Samimi, A.3    Campbell, I.L.4
  • 26
    • 0029919187 scopus 로고    scopus 로고
    • Macrophage/microglial-mediated primary demyelination and motor disease induced by the central nervous system production of interleukin-3 in transgenic mice
    • Chiang C-S, Powell HC, Gold LH, Samimi A, Campbell IL (1996): Macrophage/microglial-mediated primary demyelination and motor disease induced by the central nervous system production of interleukin-3 in transgenic mice. J Clinn Invest 97:1512-1524.
    • (1996) J Clinn Invest , vol.97 , pp. 1512-1524
    • Chiang, C.-S.1    Powell, H.C.2    Gold, L.H.3    Samimi, A.4    Campbell, I.L.5
  • 27
    • 0028914187 scopus 로고
    • Carvediol, a new beta-adrenoreceptor blocker, vasodilator and free-radical scavenger, exerts an anti-shock and endothelial protective effect in rat splanchnic ischemia and reperfusion
    • Christopher TA, Lopez BL, Yue TL, Feuerstein GZ, Ruffolo RR, Ma XL (1995): Carvediol, a new beta-adrenoreceptor blocker, vasodilator and free-radical scavenger, exerts an anti-shock and endothelial protective effect in rat splanchnic ischemia and reperfusion. J Pharmacol Exp Ther 273:64-71.
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 64-71
    • Christopher, T.A.1    Lopez, B.L.2    Yue, T.L.3    Feuerstein, G.Z.4    Ruffolo, R.R.5    Ma, X.L.6
  • 28
    • 0028006824 scopus 로고
    • Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction
    • Cockayne DA, Bodine DM, Cline A, Nienhuis AW, Dunbar CE (1994): Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction. Blood 84:2699-2710.
    • (1994) Blood , vol.84 , pp. 2699-2710
    • Cockayne, D.A.1    Bodine, D.M.2    Cline, A.3    Nienhuis, A.W.4    Dunbar, C.E.5
  • 30
    • 0030250615 scopus 로고    scopus 로고
    • Beta-amyloid converts an acute phase injury response to chronic injury responses
    • Cotman C, Tenner AJ, Cummings BJ (1996): Beta-amyloid converts an acute phase injury response to chronic injury responses. Neurobiol Aging 17:723-731.
    • (1996) Neurobiol Aging , vol.17 , pp. 723-731
    • Cotman, C.1    Tenner, A.J.2    Cummings, B.J.3
  • 31
    • 0028217866 scopus 로고
    • Cytokines and the brain corticosteroid receptor balance: Relevance to pathophysiology of neuroendocrine-immune communication
    • deKloet ER, Oitzl MS, Schobitz B (1994): Cytokines and the brain corticosteroid receptor balance: Relevance to pathophysiology of neuroendocrine-immune communication. Psychoneuroendocrinology 19:121-134.
    • (1994) Psychoneuroendocrinology , vol.19 , pp. 121-134
    • Kloet, E.R.1    Oitzl, M.S.2    Schobitz, B.3
  • 32
    • 0027314268 scopus 로고
    • Molecular profile of reactive astrocytes - Implications for their role in neurologic disease
    • Eddleston M, Mucke L (1993): Molecular profile of reactive astrocytes - implications for their role in neurologic disease. Neuroscience 54:15-36.
    • (1993) Neuroscience , vol.54 , pp. 15-36
    • Eddleston, M.1    Mucke, L.2
  • 34
    • 0030008758 scopus 로고    scopus 로고
    • Inflammation in EAE: Role of chemokine/cytokine expression by resident and infiltrating cells
    • Eng LF, Ghirnikar RS, Lee YL (1996): Inflammation in EAE: Role of chemokine/cytokine expression by resident and infiltrating cells. Neurochem Res 21:511-525.
    • (1996) Neurochem Res , vol.21 , pp. 511-525
    • Eng, L.F.1    Ghirnikar, R.S.2    Lee, Y.L.3
  • 35
    • 0024515284 scopus 로고
    • Interferon induces astrocyte maturation causing an increase in cholinergic properties of cultured human spinal cord cells
    • Erkman L, Wuarin L, Cadelli D, Kato A (1989): Interferon induces astrocyte maturation causing an increase in cholinergic properties of cultured human spinal cord cells. Dev Biol 132:375-388.
    • (1989) Dev Biol , vol.132 , pp. 375-388
    • Erkman, L.1    Wuarin, L.2    Cadelli, D.3    Kato, A.4
  • 36
    • 0023244777 scopus 로고
    • Visualization and characterization of interleukin 1 receptors in brain
    • Farrar WL, Kilian PL, Ruff MR, Hill JM, Pert CB (1987): Visualization and characterization of interleukin 1 receptors in brain. J Immunol 139:459-463.
    • (1987) J Immunol , vol.139 , pp. 459-463
    • Farrar, W.L.1    Kilian, P.L.2    Ruff, M.R.3    Hill, J.M.4    Pert, C.B.5
  • 37
    • 0028829231 scopus 로고
    • IL-6 expression in neurons of transgenic mice causes reactive astrocytosis and increase in ramified microglial cells but no neuronal damage
    • Fattori E, Lazzaro D, Musiani P, Modesti A, Alonzi T, Ciliberto G (1995): IL-6 expression in neurons of transgenic mice causes reactive astrocytosis and increase in ramified microglial cells but no neuronal damage. Eur J Neurosci 7:2441-2449.
    • (1995) Eur J Neurosci , vol.7 , pp. 2441-2449
    • Fattori, E.1    Lazzaro, D.2    Musiani, P.3    Modesti, A.4    Alonzi, T.5    Ciliberto, G.6
  • 39
    • 0024339530 scopus 로고
    • On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases
    • Frei K, Malipiero UV, Leist TP, Zinkernagel RM, Schwab ME, Fontana A (1989): On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases. Eur J Immunol 19:689-694.
    • (1989) Eur J Immunol , vol.19 , pp. 689-694
    • Frei, K.1    Malipiero, U.V.2    Leist, T.P.3    Zinkernagel, R.M.4    Schwab, M.E.5    Fontana, A.6
  • 40
    • 0027309536 scopus 로고
    • Differential expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat hypothalamus
    • Gadient RA, Otten U (1993): Differential expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat hypothalamus. Neurosci Lett 153:13-16.
    • (1993) Neurosci Lett , vol.153 , pp. 13-16
    • Gadient, R.A.1    Otten, U.2
  • 41
    • 0028069262 scopus 로고
    • Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development
    • Gadient R, Otten U (1994): Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development. Brain Res 637:10-14.
    • (1994) Brain Res , vol.637 , pp. 10-14
    • Gadient, R.1    Otten, U.2
  • 42
    • 0028989549 scopus 로고
    • Overexpression of TGF-β1 in the central nervous system of transgenic mice results in hydrocephalus
    • Galbreath E, Kim SJ, Park K, Brenner M, Messing A (1995): Overexpression of TGF-β1 in the central nervous system of transgenic mice results in hydrocephalus. J Neuropathol Exp Neurol 54:339-349.
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 339-349
    • Galbreath, E.1    Kim, S.J.2    Park, K.3    Brenner, M.4    Messing, A.5
  • 43
    • 0021340327 scopus 로고
    • Specificity of lithium (Li+) to enhance the production of colony stimulating factor (GM-CSF) from mitogen-stimulated lymphocytes in vitro
    • Gallicchio VS, Chen MG, Watts TD (1984): Specificity of lithium (Li+) to enhance the production of colony stimulating factor (GM-CSF) from mitogen-stimulated lymphocytes in vitro. Cell Immunol 85:58-66.
    • (1984) Cell Immunol , vol.85 , pp. 58-66
    • Gallicchio, V.S.1    Chen, M.G.2    Watts, T.D.3
  • 45
    • 0024213435 scopus 로고
    • Secreted peptides as regulators of neuron-glia and glia-glia interactions in the developing nervous system
    • Giulian D, Vaca K, Johnson B (1988b): Secreted peptides as regulators of neuron-glia and glia-glia interactions in the developing nervous system. J Neurosci Res 21:487-500.
    • (1988) J Neurosci Res , vol.21 , pp. 487-500
    • Giulian, D.1    Vaca, K.2    Johnson, B.3
  • 46
    • 0024852196 scopus 로고
    • The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain
    • Giulian D, Chen J, Ingeman JE, George J, Noponen M (1989): The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain. J Neurosci 9:4416-4429.
    • (1989) J Neurosci , vol.9 , pp. 4416-4429
    • Giulian, D.1    Chen, J.2    Ingeman, J.E.3    George, J.4    Noponen, M.5
  • 47
    • 0027138139 scopus 로고
    • Reactive mononuclear phagocytes release neurotoxins after ischemic and traumatic injury to the central nervous system
    • Giulian D, Corpuz M, Chapman S, Mansouri M, Robertson C (1993): Reactive mononuclear phagocytes release neurotoxins after ischemic and traumatic injury to the central nervous system. J Neurosci Res 36:681-693.
    • (1993) J Neurosci Res , vol.36 , pp. 681-693
    • Giulian, D.1    Corpuz, M.2    Chapman, S.3    Mansouri, M.4    Robertson, C.5
  • 49
    • 0029686631 scopus 로고    scopus 로고
    • Inflammatory reactions at the blood-endothelial interface in acute stroke
    • Hallenbeck JM (1996): Inflammatory reactions at the blood-endothelial interface in acute stroke. Adv Neurol 71:281-300.
    • (1996) Adv Neurol , vol.71 , pp. 281-300
    • Hallenbeck, J.M.1
  • 50
    • 0026024226 scopus 로고
    • Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures
    • Hama T, Kushima Y, Miyamoto M, Kubota M, Takei N, Hatanaka H (1991): Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures. Neuroscience 40:445-452.
    • (1991) Neuroscience , vol.40 , pp. 445-452
    • Hama, T.1    Kushima, Y.2    Miyamoto, M.3    Kubota, M.4    Takei, N.5    Hatanaka, H.6
  • 51
    • 0031052381 scopus 로고    scopus 로고
    • Amyloid, the presenilins and Alzheimer's disease
    • Hardy J (1997): Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci 20:154-159.
    • (1997) Trends Neurosci , vol.20 , pp. 154-159
    • Hardy, J.1
  • 52
    • 0030844435 scopus 로고    scopus 로고
    • Cytokine profile of myelin basic protein-reactive T cells in multiple sclerosis and healthy individuals
    • Hermans G, Stinissen P, Hauben L, Van den Berg-Loonen E, Raus J, Zheng JT (1997): Cytokine profile of myelin basic protein-reactive T cells in multiple sclerosis and healthy individuals. Ann Neurol 42:18-27.
    • (1997) Ann Neurol , vol.42 , pp. 18-27
    • Hermans, G.1    Stinissen, P.2    Hauben, L.3    Van Den Berg-Loonen, E.4    Raus, J.5    Zheng, J.T.6
  • 53
    • 0031028141 scopus 로고    scopus 로고
    • Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain
    • Heyser CJ, Masliah E, Samimi A, Campbell IL, Gold LH (1997): Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain. Proc Natl Acad Sci USA 94:1500-1505.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1500-1505
    • Heyser, C.J.1    Masliah, E.2    Samimi, A.3    Campbell, I.L.4    Gold, L.H.5
  • 54
    • 0028846560 scopus 로고
    • Are cytokines associated with neuropsychiatrie syndromes in humans?
    • Hickie I, Lloyd A (1995): Are cytokines associated with neuropsychiatrie syndromes in humans? Int J Immunopharmacol 17:677-683.
    • (1995) Int J Immunopharmacol , vol.17 , pp. 677-683
    • Hickie, I.1    Lloyd, A.2
  • 55
    • 0029051259 scopus 로고
    • Interleukin-6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients
    • Huell M, Strauss S, Volk B, Berger M, Bauer J (1995): Interleukin-6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients. Acta Neuropathol 89:544-551.
    • (1995) Acta Neuropathol , vol.89 , pp. 544-551
    • Huell, M.1    Strauss, S.2    Volk, B.3    Berger, M.4    Bauer, J.5
  • 58
    • 0028283456 scopus 로고
    • Interferon-gamma promotes cholinergic differentiation of embryonic septal nuclei and adjacent basal forebrain
    • Jonakait GM, Wei R, Sheng Z-L, Hart RP, Li N (1994): Interferon-gamma promotes cholinergic differentiation of embryonic septal nuclei and adjacent basal forebrain. Neuron 12:1149-1159.
    • (1994) Neuron , vol.12 , pp. 1149-1159
    • Jonakait, G.M.1    Wei, R.2    Sheng, Z.-L.3    Hart, R.P.4    Li, N.5
  • 59
    • 0030578454 scopus 로고    scopus 로고
    • Conditioned medium from activated microglia promotes cholinergic differentiation in the basal forebrain in vitro
    • Jonakait GM, Luskin MB, Wei R, Tian X-F, Ni L (1996): Conditioned medium from activated microglia promotes cholinergic differentiation in the basal forebrain in vitro. Dev Biol 177:85-95.
    • (1996) Dev Biol , vol.177 , pp. 85-95
    • Jonakait, G.M.1    Luskin, M.B.2    Wei, R.3    Tian, X.-F.4    Ni, L.5
  • 61
    • 0028269514 scopus 로고
    • Plasma levels of interleukin-1 beta and interleukin-6 in schizophrenia, other psychoses, and affective disorders
    • Katila H, Appelberg B, Hurme M, Rimón R (1994): Plasma levels of interleukin-1 beta and interleukin-6 in schizophrenia, other psychoses, and affective disorders. Schizophr Res 12:29-34.
    • (1994) Schizophr Res , vol.12 , pp. 29-34
    • Katila, H.1    Appelberg, B.2    Hurme, M.3    Rimón, R.4
  • 62
    • 0025367157 scopus 로고
    • Interleukin-1β inhibits long-term potentiation in the CA3 region of mouse hippocampal slices
    • Katsuki H, Nakai S, Hirai Y, Akaji K, Kiso Y, Satoh M (1990): Interleukin-1β inhibits long-term potentiation in the CA3 region of mouse hippocampal slices. Eur J Pharmacol 181:323-326.
    • (1990) Eur J Pharmacol , vol.181 , pp. 323-326
    • Katsuki, H.1    Nakai, S.2    Hirai, Y.3    Akaji, K.4    Kiso, Y.5    Satoh, M.6
  • 64
    • 0029816909 scopus 로고    scopus 로고
    • Serial measurement of interleukin-6, transforming growth factor-β, and S-100 protein in patients with acute stroke
    • Kim JS, Yoon SS, Kim YH, Ryu JS (1996): Serial measurement of interleukin-6, transforming growth factor-β, and S-100 protein in patients with acute stroke. Stroke 27:1553-1557.
    • (1996) Stroke , vol.27 , pp. 1553-1557
    • Kim, J.S.1    Yoon, S.S.2    Kim, Y.H.3    Ryu, J.S.4
  • 65
    • 0028235880 scopus 로고
    • Interleukin-1β causes the increase in anterior hypothalamic interleukin-6 during LPS-induced fever in rats
    • Klir J, McClellan JL, Kluger MJ (1994): Interleukin-1β causes the increase in anterior hypothalamic interleukin-6 during LPS-induced fever in rats. Am J Physiol 266:R1845-R1848.
    • (1994) Am J Physiol , vol.266
    • Klir, J.1    McClellan, J.L.2    Kluger, M.J.3
  • 66
    • 0026658025 scopus 로고
    • Interleukin-6 and leukemia inhibitory factor promote the survival of acetylcholinesterase-positive neurons in culture from embryonic rat spinal cord
    • Kushima Y, Hatanaka H (1992a): Interleukin-6 and leukemia inhibitory factor promote the survival of acetylcholinesterase-positive neurons in culture from embryonic rat spinal cord. Neurosci Lett 143:110-114.
    • (1992) Neurosci Lett , vol.143 , pp. 110-114
    • Kushima, Y.1    Hatanaka, H.2
  • 67
    • 0026579153 scopus 로고
    • Interleukin-6 as a neurotrophic factor for promoting the survival of cultured catecholaminergic neurons in a chemically defined medium from fetal and postnatal rat midbrains
    • Shannon, Irel.
    • Kushima Y, Hama T, Hatanaka H (1992b): Interleukin-6 as a neurotrophic factor for promoting the survival of cultured catecholaminergic neurons in a chemically defined medium from fetal and postnatal rat midbrains. Neurosci Res (Shannon, Irel.), 13(4):267-280.
    • (1992) Neurosci Res , vol.13 , Issue.4 , pp. 267-280
    • Kushima, Y.1    Hama, T.2    Hatanaka, H.3
  • 68
    • 0028073528 scopus 로고
    • Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice
    • Laye S, Parnet P, Goujon E, Dantzer R (1994): Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice. Mol Brain Res 27:157-162.
    • (1994) Mol Brain Res , vol.27 , pp. 157-162
    • Laye, S.1    Parnet, P.2    Goujon, E.3    Dantzer, R.4
  • 70
    • 0029036329 scopus 로고
    • Interleukin-1 receptor antagonist attenuates the heat stroke-induced neuronal damage by reducing the cerebral ischemia in rats
    • Lin MT, Rao TY, Jin YT, Chen CF (1995): Interleukin-1 receptor antagonist attenuates the heat stroke-induced neuronal damage by reducing the cerebral ischemia in rats. Brain Res Bull 37:595-598.
    • (1995) Brain Res Bull , vol.37 , pp. 595-598
    • Lin, M.T.1    Rao, T.Y.2    Jin, Y.T.3    Chen, C.F.4
  • 71
    • 0023761862 scopus 로고
    • Interleukin 1 increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts
    • Lindholm D, Heumann R, Hengerer B, Thoenen H (1988): Interleukin 1 increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts. J Biol Chem 263:16348-16351.
    • (1988) J Biol Chem , vol.263 , pp. 16348-16351
    • Lindholm, D.1    Heumann, R.2    Hengerer, B.3    Thoenen, H.4
  • 72
    • 0023471275 scopus 로고
    • Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve
    • Lindholm D, Heumann R, Meyer M, Thoenen H (1987): Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve. Nature 330:658-659.
    • (1987) Nature , vol.330 , pp. 658-659
    • Lindholm, D.1    Heumann, R.2    Meyer, M.3    Thoenen, H.4
  • 74
    • 0026474968 scopus 로고
    • Systemic injection of TNF-α attenuates fever due to IL-Iα and LPS in rats
    • Long NC, Morimoto A, Nakamori T, Murakami N (1992): Systemic injection of TNF-α attenuates fever due to IL-Iα and LPS in rats. Am J Physiol 263:R987-R991.
    • (1992) Am J Physiol , vol.263
    • Long, N.C.1    Morimoto, A.2    Nakamori, T.3    Murakami, N.4
  • 75
  • 76
    • 0029831358 scopus 로고    scopus 로고
    • Neuropsychiatric aspects of cytokine research: An overview
    • Malek-Ahmadi P (1996): Neuropsychiatric aspects of cytokine research: An overview. Neurosci Biobehav Rev 20:359-365.
    • (1996) Neurosci Biobehav Rev , vol.20 , pp. 359-365
    • Malek-Ahmadi, P.1
  • 77
    • 0023264201 scopus 로고
    • Interleukin 1 and myelin basic protein synergistically augment adoptive transfer activity of lymphocytes mediating experimental autoimmune encephalomyelitis in Lewis rats
    • Mannie MD, Dinarello CA, Paterson PY (1987): Interleukin 1 and myelin basic protein synergistically augment adoptive transfer activity of lymphocytes mediating experimental autoimmune encephalomyelitis in Lewis rats. J Immunol 138:4229-4235.
    • (1987) J Immunol , vol.138 , pp. 4229-4235
    • Mannie, M.D.1    Dinarello, C.A.2    Paterson, P.Y.3
  • 79
    • 0027247422 scopus 로고
    • Altered calcium signaling and neuronal injury: Stroke and Alzheimer's disease as examples
    • Mattson MP, Rydel RE, Lieberburg I, Smith-Swintosky VL (1993): Altered calcium signaling and neuronal injury: Stroke and Alzheimer's disease as examples. Ann NY Acad Sci 679:1-21.
    • (1993) Ann NY Acad Sci , vol.679 , pp. 1-21
    • Mattson, M.P.1    Rydel, R.E.2    Lieberburg, I.3    Smith-Swintosky, V.L.4
  • 81
    • 0011956385 scopus 로고
    • Chronic inflammatory mechanisms of the brain. Implications for the treatment of Alzheimer's disease
    • McGeer PL, McGeer EG (1995): Chronic inflammatory mechanisms of the brain. Implications for the treatment of Alzheimer's disease. Dementia 9:111-123.
    • (1995) Dementia , vol.9 , pp. 111-123
    • McGeer, P.L.1    McGeer, E.G.2
  • 82
    • 0031012177 scopus 로고    scopus 로고
    • Microglia in neurodegenerative disorders. Emphasis on Alzheimer's disease
    • McRae A, Dahlstroem A, Ling EA (1997): Microglia in neurodegenerative disorders. Emphasis on Alzheimer's disease. Gerontology 43:95-108.
    • (1997) Gerontology , vol.43 , pp. 95-108
    • McRae, A.1    Dahlstroem, A.2    Ling, E.A.3
  • 83
    • 0029013929 scopus 로고
    • Interactions of the nervous and immune systems in development, normal brain homeostasis, and disease
    • Merrill JE, Jonakait GM (1995): Interactions of the nervous and immune systems in development, normal brain homeostasis, and disease. FASEB J 9:611-618.
    • (1995) FASEB J , vol.9 , pp. 611-618
    • Merrill, J.E.1    Jonakait, G.M.2
  • 87
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Th1, Th2 and more
    • Mosmann TR, Sad S (1996): The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 17:138-146.
    • (1996) Immunol Today , vol.17 , pp. 138-146
    • Mosmann, T.R.1    Sad, S.2
  • 88
    • 0030874069 scopus 로고    scopus 로고
    • The role of chronic self-propagating glial responses in neurodegeneration: Implications for long-lived survivors of human immunodeficiency virus
    • Mrak RE, Griffin WST (1997): The role of chronic self-propagating glial responses in neurodegeneration: Implications for long-lived survivors of human immunodeficiency virus. J Neuro Virol 3:241-246.
    • (1997) J Neuro Virol , vol.3 , pp. 241-246
    • Mrak, R.E.1    Griffin, W.S.T.2
  • 89
    • 0026669471 scopus 로고
    • Differentiation factors, including nerve growth factor, fibroblast growth factor, and interleukin-6, induce an accumulation of an active Ras.GTP complex in rat pheochromocytoma PC12 cells
    • Nakafuku M, Satoh T, Kaziro Y (1992): Differentiation factors, including nerve growth factor, fibroblast growth factor, and interleukin-6, induce an accumulation of an active Ras.GTP complex in rat pheochromocytoma PC12 cells. J Biol Chem 267:19448-19454.
    • (1992) J Biol Chem , vol.267 , pp. 19448-19454
    • Nakafuku, M.1    Satoh, T.2    Kaziro, Y.3
  • 90
    • 0029762023 scopus 로고    scopus 로고
    • Cytokines and the pathogenesis of multiple sclerosis
    • Navikas V, Link H (1996): Cytokines and the pathogenesis of multiple sclerosis. J Neurosci Res 45:322-333.
    • (1996) J Neurosci Res , vol.45 , pp. 322-333
    • Navikas, V.1    Link, H.2
  • 91
    • 0027181354 scopus 로고
    • Interleukin-6 production by astrocytes: Induction by the neurotransmitter norepinephrine
    • Norris JG, Benveniste EN (1993): Interleukin-6 production by astrocytes: Induction by the neurotransmitter norepinephrine. J Neuroimmunol 45:137-145.
    • (1993) J Neuroimmunol , vol.45 , pp. 137-145
    • Norris, J.G.1    Benveniste, E.N.2
  • 92
    • 0028293559 scopus 로고
    • Signal transduction pathways mediating astrocyte IL-6 induction by IL-1β and tumor necrosis factor-α
    • Norris JG, Tang LP, Sparacio SM, Benveniste EN (1994): Signal transduction pathways mediating astrocyte IL-6 induction by IL-1β and tumor necrosis factor-α. J Immunol 152:841-850.
    • (1994) J Immunol , vol.152 , pp. 841-850
    • Norris, J.G.1    Tang, L.P.2    Sparacio, S.M.3    Benveniste, E.N.4
  • 93
    • 0028990468 scopus 로고
    • Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T-cell autoimmunity in experimental autoimmune encephalomyelitis and multiple sclerosis
    • Olsson T (1995): Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T-cell autoimmunity in experimental autoimmune encephalomyelitis and multiple sclerosis. Immunol Rev 144:245-268.
    • (1995) Immunol Rev , vol.144 , pp. 245-268
    • Olsson, T.1
  • 94
    • 0027964830 scopus 로고
    • Leukemia inhibitory factor, a cytokine at the interface between neurobiology and immunology
    • Patterson PH (1994): Leukemia inhibitory factor, a cytokine at the interface between neurobiology and immunology. Proc Natl Acad Sci USA 91:7833-7835.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7833-7835
    • Patterson, P.H.1
  • 95
    • 0028829601 scopus 로고
    • Cytokines in Alzheimer's disease and multiple sclerosis
    • Patterson PH (1995): Cytokines in Alzheimer's disease and multiple sclerosis. Curr Opin Neurobiol 5:642-646.
    • (1995) Curr Opin Neurobiol , vol.5 , pp. 642-646
    • Patterson, P.H.1
  • 96
    • 0027467471 scopus 로고
    • Neuronal differentiation factors/ cytokines and synaptic plasticity
    • Patterson PH, Nawa H (1993): Neuronal differentiation factors/ cytokines and synaptic plasticity. Cell 72:123-137.
    • (1993) Cell , vol.72 , pp. 123-137
    • Patterson, P.H.1    Nawa, H.2
  • 97
    • 0028174148 scopus 로고
    • Interleukin-1β inhibits Ca2+ channel currents in hippocampal neurons through protein kinase C
    • Plata-Salaman CR, Ffrench-Mullen JMH (1994): Interleukin-1β inhibits Ca2+ channel currents in hippocampal neurons through protein kinase C. Eur J Pharmacol 266:1-10.
    • (1994) Eur J Pharmacol , vol.266 , pp. 1-10
    • Plata-Salaman, C.R.1    Ffrench-Mullen, J.M.H.2
  • 98
    • 0028123096 scopus 로고
    • Developmental expression of cytokine genes in the cortex and hippocampus of the rat central nervous system
    • Pousset F (1994): Developmental expression of cytokine genes in the cortex and hippocampus of the rat central nervous system. Dev Brain Res 81:143-146.
    • (1994) Dev Brain Res , vol.81 , pp. 143-146
    • Pousset, F.1
  • 101
    • 0029560472 scopus 로고
    • Interleukin-6 mRNA expression by cortical neurons in culture: Evidence for neuronal sources of interleukin-6 production in the brain
    • Ringheim GE, Burgher KL, Heroux JA (1995): Interleukin-6 mRNA expression by cortical neurons in culture: Evidence for neuronal sources of interleukin-6 production in the brain. J Neuroimmunol 63:113-123.
    • (1995) J Neuroimmunol , vol.63 , pp. 113-123
    • Ringheim, G.E.1    Burgher, K.L.2    Heroux, J.A.3
  • 103
    • 0028288179 scopus 로고
    • Lymphokine production by human T cells in disease states
    • Romagnani S (1994): Lymphokine production by human T cells in disease states. Annu Rev Immunol 12:227-257.
    • (1994) Annu Rev Immunol , vol.12 , pp. 227-257
    • Romagnani, S.1
  • 104
    • 0030998444 scopus 로고    scopus 로고
    • Neuroimmune interactions: The role of cytokines
    • Rothwell NJ (1997): Neuroimmune interactions: The role of cytokines. Br J Pharmacol 121:841-847.
    • (1997) Br J Pharmacol , vol.121 , pp. 841-847
    • Rothwell, N.J.1
  • 105
    • 0027300024 scopus 로고
    • Involvement of cytokines in acute neurodegeneration in the CNS
    • Rothwell NJ, Relton JK (1993): Involvement of cytokines in acute neurodegeneration in the CNS. Neurosci Biobehav Rev 17:217-227.
    • (1993) Neurosci Biobehav Rev , vol.17 , pp. 217-227
    • Rothwell, N.J.1    Relton, J.K.2
  • 106
    • 0029925745 scopus 로고    scopus 로고
    • Cytokines and their receptors in the central nervous system: Physiology, pharmacology, and pathology
    • Rothwell NJ, Luheshi G, Toulmond S (1996): Cytokines and their receptors in the central nervous system: Physiology, pharmacology, and pathology. Pharmacol Ther 69:85-95.
    • (1996) Pharmacol Ther , vol.69 , pp. 85-95
    • Rothwell, N.J.1    Luheshi, G.2    Toulmond, S.3
  • 108
    • 0026766026 scopus 로고
    • TNF-α induces IL-6 production by astrocytes but not by microglia
    • Sawada M, Suzumura A, Marunouchi T (1992): TNF-α induces IL-6 production by astrocytes but not by microglia. Brain Res 583:296-299.
    • (1992) Brain Res , vol.583 , pp. 296-299
    • Sawada, M.1    Suzumura, A.2    Marunouchi, T.3
  • 109
    • 0027367308 scopus 로고
    • Expression of cytokine receptors in cultured neuronal and glial cells
    • Sawada M, Itoh Y, Suzumura A, Marunouchi T (1993): Expression of cytokine receptors in cultured neuronal and glial cells. Neurosci Lett 160:131-134.
    • (1993) Neurosci Lett , vol.160 , pp. 131-134
    • Sawada, M.1    Itoh, Y.2    Suzumura, A.3    Marunouchi, T.4
  • 110
    • 0027156783 scopus 로고
    • In vitro production of IL-6, IL-1β, and tumor necrosis factor-α by human embryonic microglial and neural cells
    • Sébire G, Emilie D, Wallon C, Héry C, Devergne O, Delfraissy JF, Galanaud P, Tardieu M (1993): In vitro production of IL-6, IL-1β, and tumor necrosis factor-α by human embryonic microglial and neural cells. J Immunol 150:1517-1523.
    • (1993) J Immunol , vol.150 , pp. 1517-1523
    • Sébire, G.1    Emilie, D.2    Wallon, C.3    Héry, C.4    Devergne, O.5    Delfraissy, J.F.6    Galanaud, P.7    Tardieu, M.8
  • 111
    • 0031038918 scopus 로고    scopus 로고
    • Alzheimer's disease: Genotypes, phenotypes, and treatments
    • Selkoe DJ (1997): Alzheimer's disease: Genotypes, phenotypes, and treatments. Science 275:630-631.
    • (1997) Science , vol.275 , pp. 630-631
    • Selkoe, D.J.1
  • 112
    • 0028341702 scopus 로고
    • Elevated interleukin-6 secretion levels by mononuclear cells of Alzheimer's patients
    • Shalit F, Sredni B, Stern L, Kott E, Huberman M (1994): Elevated interleukin-6 secretion levels by mononuclear cells of Alzheimer's patients. Neurosci Lett 174:130-132.
    • (1994) Neurosci Lett , vol.174 , pp. 130-132
    • Shalit, F.1    Sredni, B.2    Stern, L.3    Kott, E.4    Huberman, M.5
  • 113
    • 0028173033 scopus 로고
    • S100β protein expression in Alzheimer disease: Potential role in the pathogenesis of neuritic plaques
    • Sheng JG, Mrak RE, Griffin WST (1994): S100β protein expression in Alzheimer disease: Potential role in the pathogenesis of neuritic plaques. J Neurosci Res 39:398-404.
    • (1994) J Neurosci Res , vol.39 , pp. 398-404
    • Sheng, J.G.1    Mrak, R.E.2    Griffin, W.S.T.3
  • 114
    • 0029975528 scopus 로고    scopus 로고
    • Human brain S100β and S100β mRNA expression increases with age: Pathogenic implications for Alzheimer's disease
    • Sheng JG, Mrak RE, Rovnaghi CR, Lozlowska E, Van Eldik LJ, Griffin WST (1996a): Human brain S100β and S100β mRNA expression increases with age: Pathogenic implications for Alzheimer's disease. Neurobiol Aging 17:359-363.
    • (1996) Neurobiol Aging , vol.17 , pp. 359-363
    • Sheng, J.G.1    Mrak, R.E.2    Rovnaghi, C.R.3    Lozlowska, E.4    Van Eldik, L.J.5    Griffin, W.S.T.6
  • 115
    • 0007692414 scopus 로고    scopus 로고
    • In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis
    • Sheng JG, Ito K, Skinner RD, Mrak RE, Rovnaghi CR, Van Eldik LJ, Griffin WST (1996b): In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis. Neurobiol Aging 17:761-766.
    • (1996) Neurobiol Aging , vol.17 , pp. 761-766
    • Sheng, J.G.1    Ito, K.2    Skinner, R.D.3    Mrak, R.E.4    Rovnaghi, C.R.5    Van Eldik, L.J.6    Griffin, W.S.T.7
  • 116
    • 0028047684 scopus 로고
    • Speculations on antineuronal antibody-mediated neuropsychiatric disorders of childhood
    • Swedo S, Leonard H, Kiessling L (1994): Speculations on antineuronal antibody-mediated neuropsychiatric disorders of childhood. Pediatrics 93:323-326.
    • (1994) Pediatrics , vol.93 , pp. 323-326
    • Swedo, S.1    Leonard, H.2    Kiessling, L.3
  • 118
    • 0031003444 scopus 로고    scopus 로고
    • Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-α in the central nervous system
    • Taupin V, Renno T, Bourbonnière L, Peterson AC, Rodriguez M, Owens T (1997): Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-α in the central nervous system. Eur J Immunol 27:905-913.
    • (1997) Eur J Immunol , vol.27 , pp. 905-913
    • Taupin, V.1    Renno, T.2    Bourbonnière, L.3    Peterson, A.C.4    Rodriguez, M.5    Owens, T.6
  • 119
    • 0026781413 scopus 로고
    • Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons
    • Toulmond S, Vige X, Fage D, Benavides J (1992): Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons. Neurosci Lett 144:49-52.
    • (1992) Neurosci Lett , vol.144 , pp. 49-52
    • Toulmond, S.1    Vige, X.2    Fage, D.3    Benavides, J.4
  • 120
    • 0025126057 scopus 로고
    • Central nervous system toxicity of biological response modifiers
    • Triozzi PL, Kinney P, Rinehart JJ (1990): Central nervous system toxicity of biological response modifiers. Ann NY Acad Sci 594:347-354.
    • (1990) Ann NY Acad Sci , vol.594 , pp. 347-354
    • Triozzi, P.L.1    Kinney, P.2    Rinehart, J.J.3
  • 121
    • 0028965986 scopus 로고
    • Monocyte chemoattractant protein-1 messenger RNA expression in rat ischemic cortex
    • Wang X, Yue TL, Barone FC, Feuerstein GZ (1995a): Monocyte chemoattractant protein-1 messenger RNA expression in rat ischemic cortex. Stroke 26:661-666.
    • (1995) Stroke , vol.26 , pp. 661-666
    • Wang, X.1    Yue, T.L.2    Barone, F.C.3    Feuerstein, G.Z.4
  • 122
    • 0028985350 scopus 로고
    • Transforming growth factor-β1 exhibits delayed gene expression following focal cerebral ischemia
    • Wang X, Yue TL, White RF, Barone FC, Feuerstein GZ (1995b): Transforming growth factor-β1 exhibits delayed gene expression following focal cerebral ischemia. Brain Res Bull 36:607-609.
    • (1995) Brain Res Bull , vol.36 , pp. 607-609
    • Wang, X.1    Yue, T.L.2    White, R.F.3    Barone, F.C.4    Feuerstein, G.Z.5
  • 123
    • 0031015932 scopus 로고    scopus 로고
    • Interleukin-1 receptor and receptor antagonist gene expression after focal stroke in rats
    • Wang X, Barone FC, Aiyar NV, Feuerstein GZ (1997): Interleukin-1 receptor and receptor antagonist gene expression after focal stroke in rats. Stroke 28:155-162.
    • (1997) Stroke , vol.28 , pp. 155-162
    • Wang, X.1    Barone, F.C.2    Aiyar, N.V.3    Feuerstein, G.Z.4
  • 124
    • 0025007515 scopus 로고
    • Cytokines in disease
    • Whicher JT, Evans SW (1990): Cytokines in disease. Clin Chem 36:1269-1281.
    • (1990) Clin Chem , vol.36 , pp. 1269-1281
    • Whicher, J.T.1    Evans, S.W.2
  • 125
    • 84939681686 scopus 로고
    • In situ hybridization techniques for localization of interleukin 1 and interleukin 1 receptor antagonist mRNA in brain
    • Wong ML, Gold PW, Licinio J (1993): In situ hybridization techniques for localization of interleukin 1 and interleukin 1 receptor antagonist mRNA in brain. Methods Neurosci 16:81-99.
    • (1993) Methods Neurosci , vol.16 , pp. 81-99
    • Wong, M.L.1    Gold, P.W.2    Licinio, J.3
  • 126
    • 0029121104 scopus 로고
    • Microglia as a unique cellular target in the treatment of stroke: Potential neurotoxic mediators produced by activated microglia
    • Wood PL (1995): Microglia as a unique cellular target in the treatment of stroke: Potential neurotoxic mediators produced by activated microglia. Neurol Res 17:242-248.
    • (1995) Neurol Res , vol.17 , pp. 242-248
    • Wood, P.L.1
  • 127
    • 0026745023 scopus 로고
    • Long-term consequences of interleukin-6 overexpression in transgenic mice
    • Woodroofe C, Mueller W, Ruether U (1992): Long-term consequences of interleukin-6 overexpression in transgenic mice. DNA Cell Biol 11:587-592.
    • (1992) DNA Cell Biol , vol.11 , pp. 587-592
    • Woodroofe, C.1    Mueller, W.2    Ruether, U.3
  • 128
    • 0029077755 scopus 로고
    • Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-β1
    • Wyss-Coray T, Feng L, Masliah E, Ruppe MD, Lee HS, Toggas SM, Rockenstein EM, Mucke L (1995): Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-β1. Am J Pathol 147:53-67.
    • (1995) Am J Pathol , vol.147 , pp. 53-67
    • Wyss-Coray, T.1    Feng, L.2    Masliah, E.3    Ruppe, M.D.4    Lee, H.S.5    Toggas, S.M.6    Rockenstein, E.M.7    Mucke, L.8
  • 129
    • 0030753089 scopus 로고    scopus 로고
    • Interaction between amyloid precursor protein and presenilins in mammalian cells: Implications for the pathogenesis of Alzheimer disease
    • Xia W, Zheng J, Perez R, Koo EH, Selkoe DJ (1997): Interaction between amyloid precursor protein and presenilins in mammalian cells: Implications for the pathogenesis of Alzheimer disease. Proc Natl Acad Sci USA 94:8208-8213.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8208-8213
    • Xia, W.1    Zheng, J.2    Perez, R.3    Koo, E.H.4    Selkoe, D.J.5


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