메뉴 건너뛰기




Volumn 25, Issue 4, 2005, Pages 823-829

The fetal basis of amyloidogenesis: Exposure to lead and latent overexpression of amyloid precursor protein and β-amyloid in the aging brain

Author keywords

peptide; Alzheimer; CNS; Dementia; Development; Environment; Latency; Transcription

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; LEAD; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP1;

EID: 12844273354     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4335-04.2005     Document Type: Article
Times cited : (313)

References (36)
  • 3
    • 0036833795 scopus 로고    scopus 로고
    • Fetal programming of coronary heart disease
    • Barker DJ (2002) Fetal programming of coronary heart disease. Trends Endocrinol Metab 13:364-368.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 364-368
    • Barker, D.J.1
  • 5
    • 0028819961 scopus 로고
    • Neurotoxic effects of neonatal triethyltin (TET) exposure are exacerbated with aging
    • Barone Jr S, Stanton ME, Mundy WR (1995) Neurotoxic effects of neonatal triethyltin (TET) exposure are exacerbated with aging. Neurobiol Aging 16:723-735.
    • (1995) Neurobiol Aging , vol.16 , pp. 723-735
    • Barone Jr., S.1    Stanton, M.E.2    Mundy, W.R.3
  • 6
    • 0037305804 scopus 로고    scopus 로고
    • Lead-induced developmental perturbations in hippocampal Sp1 DNA-binding are prevented by zinc supplementation: In vivo evidence for Pb and Zn competition
    • Basha MR, Wei W, Brydie M, Razmiafshari M, Zawia NH (2003) Lead-induced developmental perturbations in hippocampal Sp1 DNA-binding are prevented by zinc supplementation: in vivo evidence for Pb and Zn competition. Int J Dev Neurosci 21:1-12.
    • (2003) Int J Dev Neurosci , vol.21 , pp. 1-12
    • Basha, M.R.1    Wei, W.2    Brydie, M.3    Razmiafshari, M.4    Zawia, N.H.5
  • 8
    • 0003505586 scopus 로고
    • Atlanta, GA, United States Department of Health and Human Services
    • Centers for Disease Control and Prevention (CDC) (1991) Preventing lead poisoning in young children: a statement by the CDC, Atlanta, GA, United States Department of Health and Human Services.
    • (1991) Preventing Lead Poisoning in Young Children: A Statement by the CDC
  • 9
    • 0347356360 scopus 로고    scopus 로고
    • Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1
    • Christensen MA, Zhou W, Qing H, Lehman A, Philipsen S, Song W (2004) Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1. Mol Cell Biol 24:865-874.
    • (2004) Mol Cell Biol , vol.24 , pp. 865-874
    • Christensen, M.A.1    Zhou, W.2    Qing, H.3    Lehman, A.4    Philipsen, S.5    Song, W.6
  • 10
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 11
    • 6944244417 scopus 로고    scopus 로고
    • Functional characterization of the 5′ flanking region of the BACE gene: Identification of a 91 bp fragment involved in basal level of BACE promoter expression
    • Ge YW, Maloney B, Sambamurti K, Lahiri DK (2004) Functional characterization of the 5′ flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression. FASEB J 18:1037-1039.
    • (2004) FASEB J , vol.18 , pp. 1037-1039
    • Ge, Y.W.1    Maloney, B.2    Sambamurti, K.3    Lahiri, D.K.4
  • 13
    • 0024542108 scopus 로고
    • Characterization of the 5′-end region and the first two exons of the beta-protein precursor gene
    • La Fauci G, Lahiri DK, Salton SR, Robakis NK (1989) Characterization of the 5′-end region and the first two exons of the beta-protein precursor gene. Biochem Biophys Res Commun 159:297-304.
    • (1989) Biochem Biophys Res Commun , vol.159 , pp. 297-304
    • La Fauci, G.1    Lahiri, D.K.2    Salton, S.R.3    Robakis, N.K.4
  • 14
    • 0025967258 scopus 로고
    • The promoter activity of the gene encoding Alzheimer beta-amyloid precursor protein (APP) is regulated by two blocks of upstream sequences
    • Lahiri DK, Robakis NK (1991) The promoter activity of the gene encoding Alzheimer beta-amyloid precursor protein (APP) is regulated by two blocks of upstream sequences. Mol Brain Res 9:253-257.
    • (1991) Mol Brain Res , vol.9 , pp. 253-257
    • Lahiri, D.K.1    Robakis, N.K.2
  • 16
    • 0026734018 scopus 로고
    • Premature decline in Morris water maze performance of aging micrencephalic rats
    • Lee MH, Rabe A (1992) Premature decline in Morris water maze performance of aging micrencephalic rats. Neurotoxicol Teratol 14:383-392.
    • (1992) Neurotoxicol Teratol , vol.14 , pp. 383-392
    • Lee, M.H.1    Rabe, A.2
  • 17
    • 0033635302 scopus 로고    scopus 로고
    • Effect of apolipoprotein e allele epsilon4 on the initial phase of amyloid beta-protein accumulation in the human brain
    • Morishima-Kawashima M, Oshima N, Ogata H, Yamaguchi H, Yoshimura M, Sugihara S, Ihara Y (2000) Effect of apolipoprotein E allele epsilon4 on the initial phase of amyloid beta-protein accumulation in the human brain. Am J Pathol 157:2093-2099.
    • (2000) Am J Pathol , vol.157 , pp. 2093-2099
    • Morishima-Kawashima, M.1    Oshima, N.2    Ogata, H.3    Yamaguchi, H.4    Yoshimura, M.5    Sugihara, S.6    Ihara, Y.7
  • 18
    • 0025129330 scopus 로고
    • The long-term effects of exposure to low doses of lead in childhood. An 11-year follow-up report
    • Needleman HL, Schell A, Bellinger D, Leviton A, Allred EN (1990) The long-term effects of exposure to low doses of lead in childhood. An 11-year follow-up report. N Engl J Med 322:83-88.
    • (1990) N Engl J Med , vol.322 , pp. 83-88
    • Needleman, H.L.1    Schell, A.2    Bellinger, D.3    Leviton, A.4    Allred, E.N.5
  • 21
    • 0035707425 scopus 로고    scopus 로고
    • Metabolic programming in animals
    • Ozanne SE (2001) Metabolic programming in animals. Br Med Bull 60:143-152.
    • (2001) Br Med Bull , vol.60 , pp. 143-152
    • Ozanne, S.E.1
  • 23
    • 0026507460 scopus 로고
    • The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter
    • Pollwein P, Masters C, Beyruther K (1992) The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter. Nucleic Acids Res 20:63-68.
    • (1992) Nucleic Acids Res , vol.20 , pp. 63-68
    • Pollwein, P.1    Masters, C.2    Beyruther, K.3
  • 24
    • 0033577830 scopus 로고    scopus 로고
    • Enhancer function and novel DNA binding protein activity in the near upstream beta APP gene promoter
    • Querfurth HW, Jiang J, Xia W, Selkoe DJ (1999) Enhancer function and novel DNA binding protein activity in the near upstream beta APP gene promoter. Gene 232:125-141.
    • (1999) Gene , vol.232 , pp. 125-141
    • Querfurth, H.W.1    Jiang, J.2    Xia, W.3    Selkoe, D.J.4
  • 25
    • 0142226999 scopus 로고    scopus 로고
    • Behavioral sensitization and long-term neurochemical alterations associated with the fungicide triadimefon
    • Reeves R, Thiruchelvam M, Richfield EK, Cory-Slechta DA (2003) Behavioral sensitization and long-term neurochemical alterations associated with the fungicide triadimefon. Pharmacol Biochem Behav 76:315-326.
    • (2003) Pharmacol Biochem Behav , vol.76 , pp. 315-326
    • Reeves, R.1    Thiruchelvam, M.2    Richfield, E.K.3    Cory-Slechta, D.A.4
  • 26
    • 0024942011 scopus 로고
    • Delayed neurotoxicity in monkeys exposed developmentally to methyl mercury
    • Rice D (1989) Delayed neurotoxicity in monkeys exposed developmentally to methyl mercury. Neurotoxicology 10:645-650.
    • (1989) Neurotoxicology , vol.10 , pp. 645-650
    • Rice, D.1
  • 28
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Selkoe DJ (2001) Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 81:741-766.
    • (2001) Physiol Rev , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 29
    • 0026667685 scopus 로고
    • Mechanisms of lead neurotoxicity, or looking beyond the lamppost
    • Silbergeld EK (1992) Mechanisms of lead neurotoxicity, or looking beyond the lamppost. FASEB J 6:3201-3206.
    • (1992) FASEB J , vol.6 , pp. 3201-3206
    • Silbergeld, E.K.1
  • 30
    • 0025906467 scopus 로고
    • Nerve growth factor-induced neuronal differentiation is accompanied by differential splicing of beta-amyloid precursor mRNAs in the PC12 cell line
    • Smith CJ, Wion D, Brachet P (1991) Nerve growth factor-induced neuronal differentiation is accompanied by differential splicing of beta-amyloid precursor mRNAs in the PC12 cell line. Mol Brain Res 10:351-354.
    • (1991) Mol Brain Res , vol.10 , pp. 351-354
    • Smith, C.J.1    Wion, D.2    Brachet, P.3
  • 31
    • 0032145413 scopus 로고    scopus 로고
    • Efficacy of succimer chelation for reducing brain Pb levels in a rodent model
    • Smith D, Bayer L, Strupp BJ (1998) Efficacy of succimer chelation for reducing brain Pb levels in a rodent model. Environ Res 78:168-176.
    • (1998) Environ Res , vol.78 , pp. 168-176
    • Smith, D.1    Bayer, L.2    Strupp, B.J.3
  • 34
    • 0031708579 scopus 로고    scopus 로고
    • Birth weight, adult weight, and girth as predictors of the metabolic syndrome in postmenopausal women: The Rancho Bernardo Study
    • Yarbrough DE, Barrett-Connor E, Kritz-Silverstein D, Wingard DL (1998) Birth weight, adult weight, and girth as predictors of the metabolic syndrome in postmenopausal women: the Rancho Bernardo Study. Diabetes Care 21:1652-1658.
    • (1998) Diabetes Care , vol.21 , pp. 1652-1658
    • Yarbrough, D.E.1    Barrett-Connor, E.2    Kritz-Silverstein, D.3    Wingard, D.L.4
  • 35
    • 0037812491 scopus 로고    scopus 로고
    • Transcriptional involvement in neurotoxicity
    • Zawia NH (2003) Transcriptional involvement in neurotoxicity. Toxicol Appl Pharmacol 190:177-188.
    • (2003) Toxicol Appl Pharmacol , vol.190 , pp. 177-188
    • Zawia, N.H.1
  • 36
    • 0032524391 scopus 로고    scopus 로고
    • SP1 as a target site for metal-induced perturbations of transcriptional regulation of developmental brain gene expression
    • Zawia NH, Sharan R, Brydie M, Oyama T, Crumpton T (1998) SP1 as a target site for metal-induced perturbations of transcriptional regulation of developmental brain gene expression. Brain Res Dev Brain Res 107: 291-298.
    • (1998) Brain Res Dev Brain Res , vol.107 , pp. 291-298
    • Zawia, N.H.1    Sharan, R.2    Brydie, M.3    Oyama, T.4    Crumpton, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.