-
1
-
-
32444437067
-
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
-
López-Lluch G, Hunt N, Jones B, Zhu M, Jamieson H, et al. 2006. Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency. PNAS 103:1768-1773.
-
(2006)
PNAS
, vol.103
, pp. 1768-1773
-
-
López-Lluch, G.1
Hunt, N.2
Jones, B.3
Zhu, M.4
Jamieson, H.5
-
2
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, et al. 2006. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444:337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
-
3
-
-
18144411313
-
SIRT1 Functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1 α
-
Nemoto S, Fergusson MM, Finkel T. 2005. SIRT1 Functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1 α. J Biol Chem 280:16456-16460.
-
(2005)
J Biol Chem
, vol.280
, pp. 16456-16460
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
4
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1 α and SI RT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. 2005. Nutrient control of glucose homeostasis through a complex of PGC-1 α and SI RT1. Nature 434:113-118
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
5
-
-
1842665662
-
Mitochondrial signaling: The retrograde response
-
Butow RA, Avadhani NG. 2004. Mitochondrial signaling: the retrograde response. Mol Cell 14:1-15.
-
(2004)
Mol Cell
, vol.14
, pp. 1-15
-
-
Butow, R.A.1
Avadhani, N.G.2
-
6
-
-
0033803048
-
Peroxisome proliferator-activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis
-
Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP. 2000. Peroxisome proliferator-activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest 106:847-856.
-
(2000)
J Clin Invest
, vol.106
, pp. 847-856
-
-
Lehman, J.J.1
Barger, P.M.2
Kovacs, A.3
Saffitz, J.E.4
Medeiros, D.M.5
Kelly, D.P.6
-
9
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman D. 1956. Aging: A theory based on free radical and radiation chemistry. J Gerontol 11:298-300.
-
(1956)
J Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
10
-
-
13944262937
-
Understanding the odd science of aging
-
Kirkwood TBL. 2005. Understanding the odd science of aging. Cell 120:437-447.
-
(2005)
Cell
, vol.120
, pp. 437-447
-
-
Kirkwood, T.B.L.1
-
11
-
-
0031885843
-
Role of mitochondrial DNA mutations in human aging: Implications for the central nervous system and muscle
-
Brierley EJ, Johnson MA, Lightowlers RN, James OF, Turnbull DM. 1998. Role of mitochondrial DNA mutations in human aging: implications for the central nervous system and muscle. Ann Neurol 43:217-223.
-
(1998)
Ann Neurol
, vol.43
, pp. 217-223
-
-
Brierley, E.J.1
Johnson, M.A.2
Lightowlers, R.N.3
James, O.F.4
Turnbull, D.M.5
-
13
-
-
0024366601
-
Cytochrome-c-oxidase deficient cardiomyocytes in the human heart-an age-related phenomenon. A histochemical ultracytochemical study
-
Muller-Hocker J. 1989. Cytochrome-c-oxidase deficient cardiomyocytes in the human heart-an age-related phenomenon. A histochemical ultracytochemical study. Am J Pathol 134:1167-1173.
-
(1989)
Am J Pathol
, vol.134
, pp. 1167-1173
-
-
Muller-Hocker, J.1
-
14
-
-
0027525966
-
Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly
-
Muller-Hocker J, Seibel P, Schneiderbanger K, Kadenbach B. 1993. Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly. Virchows Arch A Pathol Anat Histopathol. 422:7-15.
-
(1993)
Virchows Arch A Pathol Anat Histopathol
, vol.422
, pp. 7-15
-
-
Muller-Hocker, J.1
Seibel, P.2
Schneiderbanger, K.3
Kadenbach, B.4
-
15
-
-
0347600946
-
Mitochondrial DNA mutations in human colonic crypt stem cells
-
Taylor RW, Barron MJ, Borthwick GM, Gospel A, Chinnery PF, et al. 2003. Mitochondrial DNA mutations in human colonic crypt stem cells. J Clin Inv 112:1351-1360.
-
(2003)
J Clin Inv
, vol.112
, pp. 1351-1360
-
-
Taylor, R.W.1
Barron, M.J.2
Borthwick, G.M.3
Gospel, A.4
Chinnery, P.F.5
-
16
-
-
0034695436
-
Accumulation of defective mitochondria through delayed degradation of damaged organelles and its possible role in the ageing of post-mitotic and dividing cells
-
Kowald A, Kirkwood T. 2000. Accumulation of defective mitochondria through delayed degradation of damaged organelles and its possible role in the ageing of post-mitotic and dividing cells. J Theoretical Biol 202:145-160.
-
(2000)
J Theoretical Biol
, vol.202
, pp. 145-160
-
-
Kowald, A.1
Kirkwood, T.2
-
17
-
-
0032533691
-
Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy
-
Lee CM, Lopez ME, Weindruch R, Aiken JM. 1998. Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy. Free Radical Biol Med 25:964-972.
-
(1998)
Free Radical Biol Med
, vol.25
, pp. 964-972
-
-
Lee, C.M.1
Lopez, M.E.2
Weindruch, R.3
Aiken, J.M.4
-
18
-
-
0031081410
-
A proposed refinement of the mitochondrial free radical theory of aging
-
de Grey AD. 1997. A proposed refinement of the mitochondrial free radical theory of aging. Bioessays 19:161-166.
-
(1997)
Bioessays
, vol.19
, pp. 161-166
-
-
de Grey, A.D.1
-
19
-
-
0035097502
-
Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age
-
Elson JL, Samuels DC, Turnbull DM, Chinnery PF. 2001. Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age. Am J Hum Genet 68:802-806.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 802-806
-
-
Elson, J.L.1
Samuels, D.C.2
Turnbull, D.M.3
Chinnery, P.F.4
-
20
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K, et al. 2005. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309:481-484.
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
-
21
-
-
21244431867
-
Mitochondria, telomeres and cell senescence
-
Passos JF, von Zglinicki T. 2005. Mitochondria, telomeres and cell senescence. Exp Gerontol 40:466-472.
-
(2005)
Exp Gerontol
, vol.40
, pp. 466-472
-
-
Passos, J.F.1
von Zglinicki, T.2
-
22
-
-
13944278132
-
Mitochondria, Oxidants, and Aging
-
Balaban RS, Nemoto S, Finkel T. 2005. Mitochondria, Oxidants, and Aging. Cell 120:483-495.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
23
-
-
0344513852
-
Mitochondrial generation of reactive oxygen species and its role in aerobic life
-
Inoue M, Sato Eisuke F, Nishikawa M, Park A-M, Kira Y, et al. 2003. Mitochondrial generation of reactive oxygen species and its role in aerobic life. Current Medicinal Chem 10:2495-2505.
-
(2003)
Current Medicinal Chem
, vol.10
, pp. 2495-2505
-
-
Inoue, M.1
Sato Eisuke, F.2
Nishikawa, M.3
Park, A.-M.4
Kira, Y.5
-
24
-
-
23644433329
-
The mitochondrial genome in human adaptive radiation and disease: On the road to therapeutics and performance enhancement
-
Wallace DC. 2005. The mitochondrial genome in human adaptive radiation and disease: On the road to therapeutics and performance enhancement. Gene 354:169-180.
-
(2005)
Gene
, vol.354
, pp. 169-180
-
-
Wallace, D.C.1
-
25
-
-
0032972559
-
Positive correlation between mammalian life span and cellular resistance to stress
-
Kapahi P, Boulton ME, Kirkwood TBL. 1999. Positive correlation between mammalian life span and cellular resistance to stress. Free Radical Biol Mede 26:495-500.
-
(1999)
Free Radical Biol Mede
, vol.26
, pp. 495-500
-
-
Kapahi, P.1
Boulton, M.E.2
Kirkwood, T.B.L.3
-
26
-
-
24344480299
-
Correlations between physiology and lifespan - two widely ignored problems with comparative studies
-
Speakman JR. 2005. Correlations between physiology and lifespan - two widely ignored problems with comparative studies. Aging Cell 4:167-175.
-
(2005)
Aging Cell
, vol.4
, pp. 167-175
-
-
Speakman, J.R.1
-
28
-
-
0036829433
-
Rate of generation of oxidative stress-related damage and animal longevity
-
Barja G. 2002. Rate of generation of oxidative stress-related damage and animal longevity. Free Radical Biol Med 33:1167-1172
-
(2002)
Free Radical Biol Med
, vol.33
, pp. 1167-1172
-
-
Barja, G.1
-
29
-
-
0028528590
-
Low mitochondrial free radical production per unit O2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds
-
Barja G, Cadenas S, Rojas C, Perez-Campo R, Lopez-Torres M. 1994. Low mitochondrial free radical production per unit O2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds. Free Radic Res 21:317-327.
-
(1994)
Free Radic Res
, vol.21
, pp. 317-327
-
-
Barja, G.1
Cadenas, S.2
Rojas, C.3
Perez-Campo, R.4
Lopez-Torres, M.5
-
32
-
-
0033972463
-
Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals
-
Barja G, Herrero A. 2000. Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals. FASEB J 14.
-
(2000)
FASEB J
, vol.14
-
-
Barja, G.1
Herrero, A.2
-
33
-
-
3543017979
-
Seasonality of energetic functioning and production of reactive oxygen species by lugworm (Arenicola marina) mitochondria exposed to acute temperature changes
-
Keller M, Sommer AM, Portner HO, Abele D. 2004. Seasonality of energetic functioning and production of reactive oxygen species by lugworm (Arenicola marina) mitochondria exposed to acute temperature changes. J Exp Biol 207:2529-2538.
-
(2004)
J Exp Biol
, vol.207
, pp. 2529-2538
-
-
Keller, M.1
Sommer, A.M.2
Portner, H.O.3
Abele, D.4
-
34
-
-
1842504027
-
Activation, isolation, identification and in vitro proliferation of oval cells from adult rat livers
-
He ZP, Tan WQ, Tang YF, Zhang HJ, Feng MF. 2004. Activation, isolation, identification and in vitro proliferation of oval cells from adult rat livers. Cell Proliferation 37:177-187.
-
(2004)
Cell Proliferation
, vol.37
, pp. 177-187
-
-
He, Z.P.1
Tan, W.Q.2
Tang, Y.F.3
Zhang, H.J.4
Feng, M.F.5
-
35
-
-
22544446192
-
Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells: Novel evidence of the occurrence of Nad(P)H oxidase activity
-
Piccoli C, Ria R, Scrima R, Cela O, D'Aprile A, et al. 2005. Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells: Novel evidence of the occurrence of Nad(P)H oxidase activity. J Biol Chem 280:26467-26476.
-
(2005)
J Biol Chem
, vol.280
, pp. 26467-26476
-
-
Piccoli, C.1
Ria, R.2
Scrima, R.3
Cela, O.4
D'Aprile, A.5
-
36
-
-
27744563079
-
The expression of mitochondrial DNA transcription factors during early cardiomyocyte in vitro differentiation from human embryonic stem cells
-
St. John JC, Ramalho-Santos J, Gray HL, Petrosko P, Rawe VY, et al. 2005. The expression of mitochondrial DNA transcription factors during early cardiomyocyte in vitro differentiation from human embryonic stem cells. Cloning and Stem Cells 7:141-153.
-
(2005)
Cloning and Stem Cells
, vol.7
, pp. 141-153
-
-
St. John, J.C.1
Ramalho-Santos, J.2
Gray, H.L.3
Petrosko, P.4
Rawe, V.Y.5
-
37
-
-
8644232705
-
Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells
-
Saretzki G, Armstrong L, Leake A, Lako M, von Zglinicki T. 2004. Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells. Stem Cells 22:962-971.
-
(2004)
Stem Cells
, vol.22
, pp. 962-971
-
-
Saretzki, G.1
Armstrong, L.2
Leake, A.3
Lako, M.4
von Zglinicki, T.5
-
38
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, et al. 2006. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 12:446-451.
-
(2006)
Nat Med
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
-
39
-
-
0037069398
-
Increased mitochondrial mass in mitochondrial myopathy mice
-
Wredenberg A, Wibom R, Wilhelmsson H, Graff C, Wiener HH, et al. 2002. Increased mitochondrial mass in mitochondrial myopathy mice. PNAS 99:15066-15071.
-
(2002)
PNAS
, vol.99
, pp. 15066-15071
-
-
Wredenberg, A.1
Wibom, R.2
Wilhelmsson, H.3
Graff, C.4
Wiener, H.H.5
-
40
-
-
1542297737
-
A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts
-
Hansson A, Hance N, Dufour E, Rantanen A, Hultenby K, et al. 2004. A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts. PNAS 101:3136-3141.
-
(2004)
PNAS
, vol.101
, pp. 3136-3141
-
-
Hansson, A.1
Hance, N.2
Dufour, E.3
Rantanen, A.4
Hultenby, K.5
-
41
-
-
29144458899
-
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
-
Trifunovic A, Hansson A, Wredenberg A, Rovio AT, Dufour E, et al. 2005. Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production. PNAS 102:17993-17998.
-
(2005)
PNAS
, vol.102
, pp. 17993-17998
-
-
Trifunovic, A.1
Hansson, A.2
Wredenberg, A.3
Rovio, A.T.4
Dufour, E.5
-
42
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic A, Wredenberg A, Falkenberg M, Spelbrink JN, Rovio AT, et al. 2004. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429:417-423.
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
-
43
-
-
0031430744
-
Qualitative and quantitative changes in skeletal muscle mtdna and expression of mitochondrial-encoded genes in the human aging process
-
Barrientos A, Casademont J, Cardellach F, Ardite E, Estivill X, et al. 1997. Qualitative and quantitative changes in skeletal muscle mtdna and expression of mitochondrial-encoded genes in the human aging process. Biochemical and Molecular Medicine 62:165-171.
-
(1997)
Biochemical and Molecular Medicine
, vol.62
, pp. 165-171
-
-
Barrientos, A.1
Casademont, J.2
Cardellach, F.3
Ardite, E.4
Estivill, X.5
-
44
-
-
0031574362
-
Reduced steady-state levels of mitochondrial RNA and increased mitochondrial DNA amount in human brain with aging
-
Barrientos A, Casademont J, Cardellach F, Estivill X, Urbano-Marquez A, Nunes V. 1997. Reduced steady-state levels of mitochondrial RNA and increased mitochondrial DNA amount in human brain with aging. Molecular Brain Research 52:284-289.
-
(1997)
Molecular Brain Research
, vol.52
, pp. 284-289
-
-
Barrientos, A.1
Casademont, J.2
Cardellach, F.3
Estivill, X.4
Urbano-Marquez, A.5
Nunes, V.6
-
45
-
-
0035371185
-
Age-related mitochondrial genotypic and phenotypic alterations in human skeletal muscle
-
Pesce V, Cormio A, Fracasso F, Vecchiet J, Felzani G, et al. 2001. Age-related mitochondrial genotypic and phenotypic alterations in human skeletal muscle. Free Radical Biol Med 30:1223-1233.
-
(2001)
Free Radical Biol Med
, vol.30
, pp. 1223-1233
-
-
Pesce, V.1
Cormio, A.2
Fracasso, F.3
Vecchiet, J.4
Felzani, G.5
-
46
-
-
0038268052
-
Precise determination of mitochondrial DNA copy number in human skeletal and cardiac muscle by a PCR-based assay: Lack of change of copy number with age
-
Miller FJ, Rosenfeldt FL, Zhang C, Linnane AW, Nagley P. 2003. Precise determination of mitochondrial DNA copy number in human skeletal and cardiac muscle by a PCR-based assay: lack of change of copy number with age. Nucl Acids Res 31:e61.
-
(2003)
Nucl Acids Res
, vol.31
-
-
Miller, F.J.1
Rosenfeldt, F.L.2
Zhang, C.3
Linnane, A.W.4
Nagley, P.5
-
47
-
-
34249028642
-
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence
-
Passos JF, Saretzki G, Ahmed S, Nelson G, Richter T, et al. 2007. Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence. PLoS Biol 5:e110.
-
(2007)
PLoS Biol
, vol.5
-
-
Passos, J.F.1
Saretzki, G.2
Ahmed, S.3
Nelson, G.4
Richter, T.5
-
48
-
-
0033004248
-
Differences in electron transport potential, antioxidant defenses, and oxidant generation in young and senescent fetal lung fibroblasts (WI-38)
-
Allen RG, Tresini M, Keogh BP, Doggett DL, Cristofalo VJ. 1999. Differences in electron transport potential, antioxidant defenses, and oxidant generation in young and senescent fetal lung fibroblasts (WI-38). J Cell Physiol 180:114-122.
-
(1999)
J Cell Physiol
, vol.180
, pp. 114-122
-
-
Allen, R.G.1
Tresini, M.2
Keogh, B.P.3
Doggett, D.L.4
Cristofalo, V.J.5
-
49
-
-
0036814967
-
Replicative senescence of human fibroblasts: The role of Ras-dependent signaling and oxidative stress
-
Hutter E, Unterluggauer H, Uberall F, Schramek H, Jansen-Durr P. 2002. Replicative senescence of human fibroblasts: the role of Ras-dependent signaling and oxidative stress. Exp Gerontol 37:1165-1174.
-
(2002)
Exp Gerontol
, vol.37
, pp. 1165-1174
-
-
Hutter, E.1
Unterluggauer, H.2
Uberall, F.3
Schramek, H.4
Jansen-Durr, P.5
-
50
-
-
0017737128
-
Mitochondrial growth and division during the cell cycle in HeLa cells
-
Posakony J, England J, Attardi G. 1977. Mitochondrial growth and division during the cell cycle in HeLa cells. J. Cell Biol 74:468-491.
-
(1977)
J. Cell Biol
, vol.74
, pp. 468-491
-
-
Posakony, J.1
England, J.2
Attardi, G.3
-
51
-
-
1542373685
-
Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
-
Kelly DP, Scarpulla RC. 2004. Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev. 18:357-368.
-
(2004)
Genes Dev
, vol.18
, pp. 357-368
-
-
Kelly, D.P.1
Scarpulla, R.C.2
-
52
-
-
0014690248
-
Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat
-
Gross NJ, Getz GS, Rabinowitz M. 1969. Apparent turnover of mitochondrial deoxyribonucleic acid and mitochondrial phospholipids in the tissues of the rat. J Biol Chem 244:1552-1562.
-
(1969)
J Biol Chem
, vol.244
, pp. 1552-1562
-
-
Gross, N.J.1
Getz, G.S.2
Rabinowitz, M.3
-
53
-
-
0015239454
-
The turnover of mitochondria in a variety of tissues of young adult and aged rats
-
Menzies RA, Gold PH. 1971. The turnover of mitochondria in a variety of tissues of young adult and aged rats. J Biological Chem 246:2425-2429.
-
(1971)
J Biological Chem
, vol.246
, pp. 2425-2429
-
-
Menzies, R.A.1
Gold, P.H.2
-
54
-
-
2342544305
-
Mitochondria, oxidative stress and mitochondrial diseases
-
Cutter RG, Rodriguez H, editors. River Edge: World Scientific
-
Singh KK, Luccy BM, Zullo SJ. 2003. Mitochondria, oxidative stress and mitochondrial diseases. In: Oxidative Stress and Aging, Vol. I, pp 452-466. Cutter RG, Rodriguez H, editors. River Edge: World Scientific.
-
(2003)
Oxidative Stress and Aging
, vol.1
, pp. 452-466
-
-
Singh, K.K.1
Luccy, B.M.2
Zullo, S.J.3
-
55
-
-
0033081478
-
Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: A novel mode of inter-organelle crosstalk
-
Biswas G, Adebanjo OA, Freedman BD, Anandatheerthavarada HK, Vijayasarathy C, et al. 1999. Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk. EMBO J 18:522-533.
-
(1999)
EMBO J
, vol.18
, pp. 522-533
-
-
Biswas, G.1
Adebanjo, O.A.2
Freedman, B.D.3
Anandatheerthavarada, H.K.4
Vijayasarathy, C.5
-
56
-
-
0033580852
-
Respiratory uncoupling induces delta-aminolevulinate synthase expression through a nuclear respiratory factor-1-dependent mechanism in HeLa cells
-
Li B, Holloszy JO, Semenkovich CF. 1999. Respiratory uncoupling induces delta-aminolevulinate synthase expression through a nuclear respiratory factor-1-dependent mechanism in HeLa cells. J Biol Chem 274:17534-17540.
-
(1999)
J Biol Chem
, vol.274
, pp. 17534-17540
-
-
Li, B.1
Holloszy, J.O.2
Semenkovich, C.F.3
-
57
-
-
0033614441
-
Oxidative stress and upregulation of mitochondrial biogenesis genes in mitochondrial DNA-depleted HeLa cells
-
Miranda S, Foncea R, Guerrero J, Leighton F. 1999. Oxidative stress and upregulation of mitochondrial biogenesis genes in mitochondrial DNA-depleted HeLa cells. Biochem Biophys Res Comms 258:44-49.
-
(1999)
Biochem Biophys Res Comms
, vol.258
, pp. 44-49
-
-
Miranda, S.1
Foncea, R.2
Guerrero, J.3
Leighton, F.4
-
58
-
-
0142039781
-
Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1
-
Suliman HB, Carraway MS, Welty-Wolf KE, Whorton AR, Piantadosi CA. 2003. Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1. J Biol Chem 278:41510-41518.
-
(2003)
J Biol Chem
, vol.278
, pp. 41510-41518
-
-
Suliman, H.B.1
Carraway, M.S.2
Welty-Wolf, K.E.3
Whorton, A.R.4
Piantadosi, C.A.5
-
59
-
-
0035830867
-
Interorganellar Communication. Altered nuclear gene expression in a yeast mtDNA mutant
-
Traven A, Wong JMS, Xu D, Sopta M, Ingles CJ. 2001. Interorganellar Communication. Altered nuclear gene expression in a yeast mtDNA mutant. J Biol Chem 276:4020-4027.
-
(2001)
J Biol Chem
, vol.276
, pp. 4020-4027
-
-
Traven, A.1
Wong, J.M.S.2
Xu, D.3
Sopta, M.4
Ingles, C.J.5
-
60
-
-
23644443813
-
The retrograde response links metabolism with stress responses, chromatin-dependent gene activation, and genome stability in yeast aging
-
Jazwinski SM. 2005. The retrograde response links metabolism with stress responses, chromatin-dependent gene activation, and genome stability in yeast aging. Gene 354:22-27.
-
(2005)
Gene
, vol.354
, pp. 22-27
-
-
Jazwinski, S.M.1
-
61
-
-
0037080987
-
CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation
-
Arnould T, Vankoningsloo S, Renard P, Houbion A, Ninane N, et al. 2002. CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation. Embo J 21:53-63.
-
(2002)
Embo J
, vol.21
, pp. 53-63
-
-
Arnould, T.1
Vankoningsloo, S.2
Renard, P.3
Houbion, A.4
Ninane, N.5
-
62
-
-
26244465857
-
Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca2+-dependent pathway and a reduced mitochondrial protein import
-
Mercy L, Pauw Ad, Payen L, Tejerina S, Houbion A, et al 2005. Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca2+-dependent pathway and a reduced mitochondrial protein import. FEBS J 272:5031-5055.
-
(2005)
FEBS J
, vol.272
, pp. 5031-5055
-
-
Mercy, L.1
Pauw, A.2
Payen, L.3
Tejerina, S.4
Houbion, A.5
-
63
-
-
0037066459
-
Regulation of mitochondrial biogenesis in skeletal muscle by CaMK
-
Wu H, Kanatous SB, Thurmond FA, Gallardo T, Isotani E, et al. 2002. Regulation of mitochondrial biogenesis in skeletal muscle by CaMK. Science 296:349-352.
-
(2002)
Science
, vol.296
, pp. 349-352
-
-
Wu, H.1
Kanatous, S.B.2
Thurmond, F.A.3
Gallardo, T.4
Isotani, E.5
-
64
-
-
0038612839
-
Mitochondria to nucleus stress signaling: A distinctive mechanism of NF{kappa}B/Rel activation through calcineurin-mediated inactivation of IκBβ
-
Biswas G, Anandatheerthavarada HK, Zaidi M, Avadhani NG. 2003. Mitochondria to nucleus stress signaling: a distinctive mechanism of NF{kappa}B/Rel activation through calcineurin-mediated inactivation of IκBβ. J Cell Biol 161:507-519.
-
(2003)
J Cell Biol
, vol.161
, pp. 507-519
-
-
Biswas, G.1
Anandatheerthavarada, H.K.2
Zaidi, M.3
Avadhani, N.G.4
-
65
-
-
18244379331
-
Superoxide activates mitochondrial uncoupling proteins
-
Echtay KS, Roussel D, St-Pierre J, Jekabsons MB, Cadenas S, et al. 2002. Superoxide activates mitochondrial uncoupling proteins. Nature 415:96-99.
-
(2002)
Nature
, vol.415
, pp. 96-99
-
-
Echtay, K.S.1
Roussel, D.2
St-Pierre, J.3
Jekabsons, M.B.4
Cadenas, S.5
-
66
-
-
28644442428
-
SOD2 overexpression: Enhanced mitochondrial tolerance but absence of effect on UCP activity
-
Silva JP, Shabalina IG, Dufour E, Petrovic N, Backlund EC, et al. 2005. SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity. EMBO J 24:4061-4070.
-
(2005)
EMBO J
, vol.24
, pp. 4061-4070
-
-
Silva, J.P.1
Shabalina, I.G.2
Dufour, E.3
Petrovic, N.4
Backlund, E.C.5
-
67
-
-
0033538473
-
Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
-
Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, et al. 1999. Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1. Cell 98:115-124.
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
-
68
-
-
0035502402
-
Mitochondrial uncoupling as a target for drug development for the treatment of obesity
-
Harper JA, Dickinson K, Brand MD. 2001. Mitochondrial uncoupling as a target for drug development for the treatment of obesity. Obesity Revs 2:255-265.
-
(2001)
Obesity Revs
, vol.2
, pp. 255-265
-
-
Harper, J.A.1
Dickinson, K.2
Brand, M.D.3
-
69
-
-
0032947552
-
Interorganelle Signaling Is a Determinant of Longevity in Saccharomyces cerevisiae
-
Kirchman PA, Kim S, Lai C-Y, Jazwinski SM. 1999. Interorganelle Signaling Is a Determinant of Longevity in Saccharomyces cerevisiae. Genetics 152:179-190.
-
(1999)
Genetics
, vol.152
, pp. 179-190
-
-
Kirchman, P.A.1
Kim, S.2
Lai, C.-Y.3
Jazwinski, S.M.4
-
70
-
-
0035100306
-
Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis
-
Laun P, Pichova A, Madeo F, Fuchs J, Ellinger A, et al. 2001. Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis. Molec Microbiol 39:1166-1173.
-
(2001)
Molec Microbiol
, vol.39
, pp. 1166-1173
-
-
Laun, P.1
Pichova, A.2
Madeo, F.3
Fuchs, J.4
Ellinger, A.5
-
71
-
-
3042781117
-
Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts
-
Hutter E, Renner K, Pfister G, Stockl P, Jansen-Durr P, Gnaiger E. 2004, Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts. Biochem J 380:919-928.
-
(2004)
Biochem J
, vol.380
, pp. 919-928
-
-
Hutter, E.1
Renner, K.2
Pfister, G.3
Stockl, P.4
Jansen-Durr, P.5
Gnaiger, E.6
-
72
-
-
0036420161
-
Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence
-
Lee HC, Yin PH, Chi CW, Wei YH. 2002. Increase in mitochondrial mass in human fibroblasts under oxidative stress and during replicative cell senescence. J Biomed Sci 9:517-526.
-
(2002)
J Biomed Sci
, vol.9
, pp. 517-526
-
-
Lee, H.C.1
Yin, P.H.2
Chi, C.W.3
Wei, Y.H.4
-
73
-
-
0037147103
-
Rates of behavior and aging specified by mitochondrial function during development
-
Dillin A, Hsu A-L, Arantes-Oliveira N, Lehrer-Graiwer J, Hsin H, et al. 2002. Rates of behavior and aging specified by mitochondrial function during development. Science 298:2398-2401.
-
(2002)
Science
, vol.298
, pp. 2398-2401
-
-
Dillin, A.1
Hsu, A.-L.2
Arantes-Oliveira, N.3
Lehrer-Graiwer, J.4
Hsin, H.5
-
74
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, et al. 2006. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127:397-408.
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
-
75
-
-
6044224889
-
Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes
-
Shen X, Zheng S, Thongboonkerd V, Xu M, Pierce WM Jr, et al. 2004. Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes. Am J Physiol Endocrinol Metab 287:E896-905.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
-
-
Shen, X.1
Zheng, S.2
Thongboonkerd, V.3
Xu, M.4
Pierce Jr, W.M.5
-
76
-
-
0035854649
-
Increased expression of mitochondrial transcription factor A and nuclear respiratory factor-1 in skeletal muscle from aged human subjects
-
Lezza AMS, Pesce V, Cormio A, Fracasso F, Vecchiet J, et al. 2001. Increased expression of mitochondrial transcription factor A and nuclear respiratory factor-1 in skeletal muscle from aged human subjects. FEBS Letters 501:74-78.
-
(2001)
FEBS Letters
, vol.501
, pp. 74-78
-
-
Lezza, A.M.S.1
Pesce, V.2
Cormio, A.3
Fracasso, F.4
Vecchiet, J.5
-
77
-
-
0037474446
-
Acetylation and level of mitochondrial transcription factor A in several organs of young and old rats
-
Dinardo MM, Musicco C, Fracasso F, Milella F, Gadaleta MN, et al. 2003. Acetylation and level of mitochondrial transcription factor A in several organs of young and old rats. Biochem Biophys Res Comms 301:187-191.
-
(2003)
Biochem Biophys Res Comms
, vol.301
, pp. 187-191
-
-
Dinardo, M.M.1
Musicco, C.2
Fracasso, F.3
Milella, F.4
Gadaleta, M.N.5
-
78
-
-
0030451773
-
Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle
-
Rooyackers OE, Adey DB, Ades PA, Nair KS. 1996. Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle. Proc Natl Acad Sci USA 93:15364-15369.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 15364-15369
-
-
Rooyackers, O.E.1
Adey, D.B.2
Ades, P.A.3
Nair, K.S.4
-
79
-
-
0033610079
-
Gene expression profile of aging and its retardation by caloric restriction
-
Lee CK, Klopp RG, Weindruch R, Prolla TA. 1999. Gene expression profile of aging and its retardation by caloric restriction. Science 285:1390-1393.
-
(1999)
Science
, vol.285
, pp. 1390-1393
-
-
Lee, C.K.1
Klopp, R.G.2
Weindruch, R.3
Prolla, T.A.4
-
80
-
-
0037517056
-
Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix
-
Bakala H, Delaval E, Hamelin M, Bismuth J, Borot-Laloi C, et al. 2003. Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix. Eur J Biochem 270:2295-2302.
-
(2003)
Eur J Biochem
, vol.270
, pp. 2295-2302
-
-
Bakala, H.1
Delaval, E.2
Hamelin, M.3
Bismuth, J.4
Borot-Laloi, C.5
-
81
-
-
0036236006
-
The mitochondrial-lysosomal axis theory of aging: Accumulation of damaged mitochondria as a result of imperfect autophagocytosis
-
Brunk UT, Terman A. 2002. The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis. Eur J Biochem 269:1996-2002.
-
(2002)
Eur J Biochem
, vol.269
, pp. 1996-2002
-
-
Brunk, U.T.1
Terman, A.2
-
82
-
-
0034117954
-
Protein oxidation and degradation during proliferative senescence of human MRC-5 fibroblasts
-
Sitte N, Merker K, von Zglinicki T, Grune T. 2000. Protein oxidation and degradation during proliferative senescence of human MRC-5 fibroblasts. Free Radical Biology and Medicine 28:701-708.
-
(2000)
Free Radical Biology and Medicine
, vol.28
, pp. 701-708
-
-
Sitte, N.1
Merker, K.2
von Zglinicki, T.3
Grune, T.4
-
83
-
-
0038047140
-
Proteome analysis of dermal fibroblasts cultured in vitro from human healthy subjects of different ages
-
Boraldi F, Bini L, Liberatori S, Armini A, Pallini V, et al. 2003. Proteome analysis of dermal fibroblasts cultured in vitro from human healthy subjects of different ages. Proteomics 3:917-929.
-
(2003)
Proteomics
, vol.3
, pp. 917-929
-
-
Boraldi, F.1
Bini, L.2
Liberatori, S.3
Armini, A.4
Pallini, V.5
-
84
-
-
0036961940
-
Proteasome Inhibition Enhances Lipofuscin Formation
-
Terman A, Sandberg S. 2002. Proteasome Inhibition Enhances Lipofuscin Formation. Ann NY Acad Sci 973:309-312.
-
(2002)
Ann NY Acad Sci
, vol.973
, pp. 309-312
-
-
Terman, A.1
Sandberg, S.2
-
85
-
-
0035092972
-
Lipofuscin accumulation in proliferating fibroblasts in vitro: An indicator of oxidative stress
-
Sitte N, Merker K, Grune T, von Zglinicki T. 2001. Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress. Experimental Gerontology 36:475-486.
-
(2001)
Experimental Gerontology
, vol.36
, pp. 475-486
-
-
Sitte, N.1
Merker, K.2
Grune, T.3
von Zglinicki, T.4
-
86
-
-
0000466588
-
Respiratory chain linked H2O2 production in pigeon heart mitochondria
-
Loschen G, Flohe L, Chance B. 1971. Respiratory chain linked H2O2 production in pigeon heart mitochondria. FEBS Letters 18:261-264.
-
(1971)
FEBS Letters
, vol.18
, pp. 261-264
-
-
Loschen, G.1
Flohe, L.2
Chance, B.3
-
87
-
-
0031459980
-
Extrachromosomal rDNA circles - a cause of aging in yeast
-
Sinclair DA, Guarente L. 1997. Extrachromosomal rDNA circles - a cause of aging in yeast. Cell 91:1033-1042.
-
(1997)
Cell
, vol.91
, pp. 1033-1042
-
-
Sinclair, D.A.1
Guarente, L.2
-
88
-
-
0000063597
-
Asymmetric cell division
-
Jan YN, Jan LY. 1998. Asymmetric cell division. Nature 392:775-778.
-
(1998)
Nature
, vol.392
, pp. 775-778
-
-
Jan, Y.N.1
Jan, L.Y.2
-
89
-
-
0037203958
-
Asymmetric segregation of mitochondria and mortalin correlates with the multi-lineage potential of inner ear sensory cell progenitors in vitro
-
Rivolta MN, Holley MC. 2002. Asymmetric segregation of mitochondria and mortalin correlates with the multi-lineage potential of inner ear sensory cell progenitors in vitro. Develop Brain Res 133:49-56.
-
(2002)
Develop Brain Res
, vol.133
, pp. 49-56
-
-
Rivolta, M.N.1
Holley, M.C.2
-
90
-
-
0033525615
-
The machinery of mitochondrial inheritance and behavior
-
Yaffe MP. 1999. The machinery of mitochondrial inheritance and behavior. Science 283:1493-1497.
-
(1999)
Science
, vol.283
, pp. 1493-1497
-
-
Yaffe, M.P.1
-
91
-
-
0037540665
-
The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells
-
Piper PW, Jones GW, Bringloe D, Harris N, MacLean M, Mollapour M. 2002. The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells. Aging cell 1:149-157.
-
(2002)
Aging cell
, vol.1
, pp. 149-157
-
-
Piper, P.W.1
Jones, G.W.2
Bringloe, D.3
Harris, N.4
MacLean, M.5
Mollapour, M.6
-
92
-
-
0035325241
-
Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence
-
Coates PJ, Nenutil R, McGregor A, Picksley SM, Crouch DH, et al. 2001. Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence. Experimental Cell Res 265:262-273.
-
(2001)
Experimental Cell Res
, vol.265
, pp. 262-273
-
-
Coates, P.J.1
Nenutil, R.2
McGregor, A.3
Picksley, S.M.4
Crouch, D.H.5
-
93
-
-
0008688565
-
Association of mitochondria with microtubules in cultured cells
-
Heggeness MH, Simon M, Singer SJ. 1978. Association of mitochondria with microtubules in cultured cells. Proc Natl Acad Sci USA 75:3863-3866.
-
(1978)
Proc Natl Acad Sci USA
, vol.75
, pp. 3863-3866
-
-
Heggeness, M.H.1
Simon, M.2
Singer, S.J.3
-
94
-
-
0021179316
-
Increased organization of cytoskeleton accompanying the aging of human fibroblasts in vitro
-
Wang E, Gundersen D. 1984. Increased organization of cytoskeleton accompanying the aging of human fibroblasts in vitro. Exp Cell Res 154:191-202.
-
(1984)
Exp Cell Res
, vol.154
, pp. 191-202
-
-
Wang, E.1
Gundersen, D.2
-
96
-
-
33745026738
-
Autophagy and aging: The importance of maintaining "clean" cells
-
Cuervo AM, Bergamin E, Brunk UT, Droge W, Ffrench M, Terman A. 2005. Autophagy and aging: the importance of maintaining "clean" cells. Autophagy 1:131-140.
-
(2005)
Autophagy
, vol.1
, pp. 131-140
-
-
Cuervo, A.M.1
Bergamin, E.2
Brunk, U.T.3
Droge, W.4
Ffrench, M.5
Terman, A.6
-
97
-
-
34548720098
-
-
Passos JF. 2006. PhD thesis: Mitochondrial dysfunction in cellular senescence. Newcastle upon Tyne: Newcastle University.
-
Passos JF. 2006. PhD thesis: Mitochondrial dysfunction in cellular senescence. Newcastle upon Tyne: Newcastle University.
-
-
-
-
98
-
-
9244238708
-
Common and cell type-specific responses of human cells to mitochondrial dysfunction
-
Miceli MV, Jazwinski SM. 2005. Common and cell type-specific responses of human cells to mitochondrial dysfunction. Exp Cell Res 302:270-280.
-
(2005)
Exp Cell Res
, vol.302
, pp. 270-280
-
-
Miceli, M.V.1
Jazwinski, S.M.2
|