Mitochondria to nucleus stress signaling: A distinctive mechanism of NFκB/Rel activation through calcineurin-mediated inactivation of IκBβ

Journal of Cell Biology

Volumn 161, Issue 3, 2003, Pages 507-519

  Biswas, Gopa ^a   Anandatheerthavarada, Hindupur K ^a   Zaidi, Mone ^b   Avadhani, Narayan G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Calcineurin; Dephosphorylation; I B ; Mitochondrial stress signaling; NF B Rel activation

Indexed keywords

CALCINEURIN; CALCIUM ION; CATHEPSIN L; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATASE; TACROLIMUS; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR REL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; CROSS LINKING; DEPHOSPHORYLATION; ENZYME SUBSTRATE; GENE EXPRESSION; GENE TARGETING; MITOCHONDRION; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STRESS;

ANIMALS; BINDING SITES; CALCINEURIN; CALCIUM SIGNALING; CELL NUCLEUS; CELLS, CULTURED; ENZYME INHIBITORS; EUKARYOTIC CELLS; I-KAPPA B PROTEINS; MICE; MITOCHONDRIA; MUTATION; NF-KAPPA B; ONCOGENE PROTEINS V-REL; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; SERINE; STRESS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

ANIMALIA;

EID: 0038612839     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200211104     Document Type: Article

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