Replicative senescence of human fibroblasts: The role of Ras-dependent signaling and oxidative stress

Experimental Gerontology

Volumn 37, Issue 10-11, 2002, Pages 1165-1174

  Hütter, Eveline ^a   Unterluggauer, Hermann ^a   Überall, Florian ^b   Schramek, Herbert ^c   Jansen Dürr, Pidder ^a  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b Inst Medizinische Chemie Biochemie   (Austria)

^c Institut für Physiologie   (Austria)

Author keywords

Aging; MAP kinase; Oxidative stress; Protein kinase C; Ras; Senescence

Indexed keywords

ENZYME; EXTRACELLULAR REGULATED KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN KINASE; RAF PROTEIN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; MAP2K1 PROTEIN, HUMAN; MAP2K2 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEIN KINASE C; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE 1;

AGED; CELL GROWTH; CONFERENCE PAPER; CONTROLLED STUDY; FIBROBLAST; GROWTH DISORDER; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; SENESCENCE; SIGNAL TRANSDUCTION; ARTICLE; CELL AGING; CELL COMMUNICATION; CELL CULTURE; CYTOLOGY; METABOLISM; PHYSIOLOGY; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL AGING; CELL COMMUNICATION; CELLS, CULTURED; FIBROBLASTS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RAS PROTEINS; REACTIVE OXYGEN SPECIES;

EID: 0036814967     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(02)00136-5     Document Type: Conference Paper

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