Tristetraprolin regulates TNF TNF-α mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways

Molecular Immunology

Volumn 45, Issue 1, 2008, Pages 13-24

  Deleault, Kristen M ^a   Skinner, Stephen J ^b   Brooks, Seth A ^a,b  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b VA MEDICAL CENTER   (United States)

Author keywords

MAP Kinase; Post transcriptional regulation; Proteasome; TNF ; Tristetraprolin

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEASOME; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME STABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; RNA TRANSLATION;

3' UNTRANSLATED REGIONS; ANIMALS; CELL LINE; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LEUPEPTINS; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICE; MODELS, BIOLOGICAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BIOSYNTHESIS; RNA STABILITY; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34548241289     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.05.017     Document Type: Article

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