Analysis of the function, expression, and subcellular distribution of human tristetraprolin

Arthritis and Rheumatism

Volumn 46, Issue 5, 2002, Pages 1362-1370

  Brooks, Seth A ^a,b   Connolly, John E ^a   Diegel, Roger J ^a   Fava, Roy A ^b   Rigby, William F C ^a,c  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^b VA MEDICAL CENTER   (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRISTETRAPROLIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ARTICLE; CELLULAR DISTRIBUTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; REPORTER GENE; RHEUMATOID ARTHRITIS; RNA BINDING; TRANSCRIPTION REGULATION;

3' UNTRANSLATED REGIONS; ANTIBODY SPECIFICITY; ARTHRITIS, RHEUMATOID; BASE SEQUENCE; CELL LINE; DNA-BINDING PROTEINS; GENE EXPRESSION; HUMANS; IMMEDIATE-EARLY PROTEINS; KIDNEY; LUCIFERASES; MOLECULAR SEQUENCE DATA; MYELOID CELLS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; TRANSFECTION; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036090190     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10235     Document Type: Article

References (30)

1. Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies
2. The biology of cachectin/TNF: A primary mediator of the host response
3. Extinction of the tumor necrosis factor locus and of genes encoding the lipopolysaccharide signaling pathway
4. A pathogenetic role for TNFα in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency
5. A growth factor-inducible nuclear protein with a novel cysteine/histidine repetitive sequence
6. A human putative lymphocyte G0/G1 switch gene homologous to a rodent gene encoding a zinc-binding potential transcription factor
7. Rapid insulin-stimulated accumulation of an mRNA encoding a proline-rich protein
8. A corrected sequence for the predicted protein from the mitogen-inducible TIS11 primary response gene
9. Nucleotide sequence of a cDNA encoding TIS11, a message induced in Swiss 3T3 cells by the tumor promoter tetradecanoyl phorbol acetate
10. Metal binding properties and secondary structure of the zinc-binding domain of Nup475
11. Interactions of CCCH zinc finger proteins with mRNA: Binding of tristetraprolin-related zinc finger proteins to AU-rich elements and destabilization of mRNA
12. Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice: Evidence that monocyte/macrophage progenitors may be responsible for TNFα overproduction
13. Feedback inhibition of macrophage tumor necrosis factorα production by tristetraprolin
14. Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor α mRNA
15. Interactions of CCCH zinc-finger proteins with mRNA tristetraprolin-mediated AU-rich element-dependent mRNA degradation can occur in the absence of a polyA tail
16. Rapid degradation of AU-rich element (ARE) mRNAs is activated by ribosome transit and blocked by secondary structure at any position 5′ to the ARE
17. Selective destabilization of short-lived mRNAs with the granulocyte-macrophage colony-stimulating factor AU-rich 3′ noncoding region is mediated by a cotranslational mechanism
18. Basic local alignment search tool
19. Modulation of AUUUA response element binding by heterogeneous nuclear ribonucleoprotein A1 in human T lymphocytes: The roles of cytoplasmic location, transcription, and phosphorylation
20. Histone mRNA degradation in vivo: The first detectable step occurs at or near the 3′ terminus
21. Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation
22. Identification of AUF1 (heterogeneous nuclear ribonucleoprotein D) as a component of the α-globin mRNA stability complex
23. AUF1 binding affinity to A+U-rich elements correlates with rapid mRNA degradation
24. Characterization of the mRNA ligands bound by the RNA binding protein hnRNP A2 utilizing a novel in vivo technique
25. Synovial localization of tumor necrosis factor in patients with rheumatoid arthritis
26. The human TTP protein: Sequence, alignment with related proteins, and chromosomal localization of the mouse and human genes
27. The influence of 5′-secondary structures upon ribosome binding to mRNA during translation in yeast
28. Messenger RNA deadenylation precedes decapping in mammalian cells