Role of c-Jun N-terminal kinase on lipopolysaccharide induced maturation of human monocyte-derived dendritic cells

International Immunology

Volumn 16, Issue 12, 2004, Pages 1701-1709

  Nakahara, Takeshi ^a   Uchi, Hiroshi ^a   Urabe, Kazunori ^a   Chen, Qijie ^a   Furue, Masutaka ^a   Moroi, Yoichi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Cytokines; Mitogen activated protein kinases; Signal transduction; Th1 2 cells

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; B7 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; OVALBUMIN; PROTEIN P70; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN PRESENTING CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL MATURATION; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DOWN REGULATION; HUMAN; HUMAN TISSUE; MONOCYTE; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TH2 CELL; UPREGULATION;

ANTHRACENES; ANTIGENS, CD; BIOLOGICAL TRANSPORT; CELL DIFFERENTIATION; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DENDRITIC CELLS; DEXTRANS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; FLUORESCEIN-5-ISOTHIOCYANATE; HLA-DR ANTIGENS; HUMANS; IMIDAZOLES; INTERLEUKIN-12; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN SUBUNITS; PYRIDINES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 10844273239     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxh171     Document Type: Article

References (44)

1. Banchereau, J. and Steinman, R. M. 1998. Dendritic cells and the control of immunity. Nature 392:245.
2. Cella, M., Sallusto, F. and Lanzavecchia, A. 1997. Origin, maturation and antigen presenting function of dendritic cells. Curr. Opin. Immunol. 9:10.
3. Sallusto, F. and Lanzavecchia, A. 1994. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor. J. Exp. Med. 179:1109.
4. Sallusto, F., Cella, M., Danieli, C. and Lanzavecchia, A. 1995. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J. Exp. Med. 182:389.
5. + dendritic cells. Proc. Natl Acad. Sci. USA 93:2588.
6. Banchereau, J., Briere, F., Caux, C., Davoust, J., Lebecque, S., Liu, Y. J., Pulendran, B. and Palucka, K. 2000. Immunobiology of dendritic cells. Annu. Rev. Immunol. 18:767.
7. Verhasselt, V., Buelens, C., Willems, F., De Groote, D., Haeffner-Cavaillon, N. and Goldman, M. 1997. Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway. J. Immunol. 158:2919.
8. Caux, C., Massacrier, C., Vanbervliet, B., Dubois, B., Van Cooten, C., Durand, I. and Banchereau, J. 1994. Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med. 180:1263.
9. Jakob, T, Walker, P.S., Krieg, A. M., Udey, M. C. and Vogel, J. C. 1998. Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA. J. Immunol. 161:3042.
10. Aiba, S., Terunuma, A., Manome, H. and Tagami, H. 1997. Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules. Eur. J. Immunol. 27:3031.
11. Caux, C., Dezutter-Dambuyant, C., Schmitt, D. and Banchereau, J. 1992. GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells. Nature 360:258.
12. + progenitors in human bone marrow. J. Immunol. 149:2681.
13. Boulton, T. G., Nye, S. H., Robbins, D. J. et al. 1991. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 65:663.
14. Derijard, B., Hibi, M., Wu, I. H., Barrett, T., Su, B., Deng, T., Karin, M. and Davis, R. J. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025.
15. Lee, J. C., Laydon, J. T., McDonnell, P. C. et al. 1994. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372:739.
16. Arrighi, J. F., Rebsamen, M., Rousset, F., Kindler, V. and Hauser, C. 2001. A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-α, and contact sensitizers. J. Immunol. 166:3837.
17. Ardeshna, K. M., Pizzey, A. R., Devereux, S. and Khwaja, A. 2000. The P13 kinase, p38 MAP kinase, and NF-κB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells. Blood 96:1039.
18. Rescigno, M., Martino, M., Sutherland, C. L., Gold, M. R. and Ricciardi-Castagnoli, P. 1998. Dendritic cell survival and maturation are regulated by different signaling pathways. J. Exp. Med. 188:2175.
19. Puig-Kroger, A., Relloso, M., Fernandez-Capetillo, O., Zubiaga, A., Silva, A., Bernabeu, C. and Corbi, A. L. 2001. Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells. Blood 98:2175.
20. Uchi, H., Koga, T., Urabe, K., Moroi, Y. and Furue, M. 2003. CX-659S, a diaminouracil derivative, indirectly inhibits the function of Langerhans cells by blocking the MEK1/2-Erk1/2 pathway in keratinocytes. J. Invest. Dermatol. 120:983.
21. Bennett, B. L., Sasaki, D. T., Murray, B. W. et al. 2001. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc. Natl Acad. Sci. USA 98:13681.
22. Utsugi, M., Dobashi, K., Ishizuka, T., Endou, K., Hamuro, J., Murata, Y., Nakazawa, T. and Mori, M. 2003. c-Jun N-terminal kinase negatively regulates lipopolysaccharide-induced IL-12 production in human macrophages: role of mitogen-activated protein kinase in glutathione redox regulation of IL-12 production. J. Immunol. 171:628.
23. Wilfred, L., Ma, W., Gee, K., Aucoin, S., Nandan, D., Diaz-Mitoma, F., Kozlowski, M. and Kumar, A. 2002. Distinct role of p38 and c-Jun N-terminal kinase in IL-10-dependentand IL-10-independent regulation of the costimulatory molecule B7.2 in lipopolysaccharide-stimulated human monocytic cells. J. Immunol. 168:1759.
24. Schmid, I., Uittenbogaart, C. H., Keld, B. and Giorgi, J. V. 1994. A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry. J. Immunol. Methods 170:145.
25. Kalinski, P., Hilkens, C. M., Snijders, A., Snijdewint, F. G. and Kapsenberg, M. L. 1997. IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells. J. Immunol. 159:28.
26. Gagliardi, M. C., Sallusto, F., Marinaro, M., Langenkamp, A., Lanzavecchia, A. and De Magistris, M. T. 2000. Cholera toxin induces maturation of human dendritic cells and licences them for Th2 priming. Eur. J. Immunol. 30:2394.
27. la Sala, A., Ferrari, D., Corinti, S., Cavani, A., Di Virgilio, F. and Girolomoni, G. 2001. Extracellular ATP induces a distorted maturation of dendritic cells and inhibits their capacity to initiate Th 1 responses. J. Immunol. 166:1611.
28. Gosset, P., Bureau, F., Angeli, V., Pichavant, M., Faveeuw, C., Tonnel, A. B. and Trottein, F. 2003. Prostaglandin D2 affects the maturation of human monocyte-derived dendritic cells: consequence on the polarization of naive Th cells. J. Immunol. 170:4943.
29. Rescigno, M., Winzler, C., Delia, D., Mutini, C., Lutz, M. and Ricciardi-Castagnoli, P. 1997. Dendritic cell maturation is required for initiation of the immune response. J. Leukocyte Biol. 61:415.
30. Jonuleit, H., Kuhn, U., Muller, G., Steinbrink, K., Paragnik, L., Schmitt, E., Knop, J. and Enk, A. H. 1997. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur. J. Immunol. 27:3135.
31. Akira, S., Takeda, K. and Kaisho, T. 2001. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2:675.
32. Muzio, M., Bosisio, D., Polentarutti, N. et al. 2000. Differential expression and regulation of Toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J. Immunol. 164:5998.
33. Visintin, A., Mazzoni, A., Spitzer, J. H., Wyllie, D. H., Dower, S. K. and Segal, D. M. 2001. Regulation of Toll-like receptors in human monocytes and dendritic cells. J. Immunol. 166:249.
34. Sato, K., Nagayama, H., Tadokoro, K., Juji, T. and Takahashi, T. A. 1999. Extracellular signal-regulated kinase, stress-activated protein kinase/c-Jun N-terminal kinase, and p38mapk are involved in IL-10-mediated selective repression of TNF-α-induced activation and maturation of human peripheral blood monocyte-derived dendritic cells. J. Immunol. 162:3865.
35. Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251.
36. Gupta, S., Barrett, T., Whitmarsh, A. J., Cavanagh, J., Sluss, H. K., Derijard, B. and Davis, R. J. 1996. Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J. 15:2760.
37. Yang, D. D., Kuan, C. Y., Whitmarsh, A. J., Rincon, M., Zheng, T S., Davis, R. J., Rakic, P. and Flavell, R. A. 1997. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 389:865.
38. Yang, D. D., Conze, D., Whitmarsh, A. J., Barrett, T., Davis, R. J., Rincon, M. and Flavell, R. A. 1998. Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2. Immunity 9:575.
39. Dong, C., Yang, D. D., Wysk, M., Whitmarsh, A. J., Davis, R. J. and Flavell, R. A. 1998. Defective T cell differentiation in the absence of Jnk1. Science 282:2092.
40. Vo, N. and Goodman, R. H. 2001. CREB-binding protein and p300 in transcriptional regulation. J. Biol. Chem. 276:13505.
41. Shenkar, R., Yum, H. K., Arcaroli, J., Kupfner, J. and Abraham, E. 2001. Interactions between CBP, NF-kappaB, and CREB in the lungs after hemorrhage and endotoxema. Am. J. Physiol. Lung Cell. Mol. Physiol. 281:418.
42. Caelles, C., Gonzalez-Sancho, J. M. and Munoz, A. 1997. Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway. Genes Dev. 11:3351.
43. Kuchroo, V. K., Das, M. P., Brown, J. A., Ranger, A. M., Zamvil, S. S., Sobel, R. A., Weiner, H. L., Nabavi, N. and Glimcher, L. H. 1995. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 80:707.
44. Freeman, G. J., Boussiotis, V. A., Anumanthan, A. et al. 1995. B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4. Immunity 2:523.