Toll like receptors and acute allograft rejection

Transplant Immunology

Volumn 17, Issue 1, 2006, Pages 11-15

  Goldstein, Daniel R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dendritic cell; Innate immunity; Toll like receptor

Indexed keywords

TOLL LIKE RECEPTOR;

ACUTE GRAFT REJECTION; ALLOIMMUNITY; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; GENOTYPE; GRAFT RECIPIENT; HUMAN; IMMUNOBIOLOGY; IMMUNOGENETICS; IMMUNOREACTIVITY; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; INNATE IMMUNITY; LUNG TRANSPLANTATION; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; REVIEW; RODENT; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ACUTE DISEASE; ANIMALS; DENDRITIC CELLS; GRAFT REJECTION; HUMANS; IMMUNITY, NATURAL; LIGANDS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; TRANSPLANTATION IMMUNOLOGY; TRANSPLANTATION, HOMOLOGOUS;

EID: 34347372412     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2006.09.012     Document Type: Review

References (59)

1. Banchereau J., and Steinman R.M. Dendritic cells and the control of immunity. Nature 392 6673 (1998) 245
2. Akira S., and Takeda K. Toll-like receptor signalling. Nat Rev Immunol 4 7 (2004) 499
3. Iwasaki A., and Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 5 10 (2004) 987
4. Medzhitov R., Preston-Hurlburt P., and Janeway Jr. C.A. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388 6640 (1997) 394
5. Hoffmann J.A., R, and JM. Drosophila innate immunity: an evolutionary perspective. Nat Immunol 3 2 (2002) 121
6. Akira S., Uematsu S., and Takeuchi O. Pathogen recognition and innate immunity. Cell 124 4 (2006) 783
7. Yarovinsky F., Zhang D., Andersen J.F., Bannenberg G.J., Serhan E.N., Hayden M.S., et al. TLR11 activation of dendritic cells by a protozoan profilin-like protein. Science 308 5728 (2005) 1626
8. Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 1 2 (2001) 135
9. Barton G.M., and Medzhitov R. Toll-like receptor signaling pathways. Science 300 5625 (2003) 1524
10. Cook C., Pisetsky D., and Schwartz D. Toll-like receptors in the pathogeneis of human disease. Nat Immunol 5 10 (2004) 975
11. Horng T., Barton G.M., and Medzhitov R. TIRAP: an adapter molecule in the Toll signaling pathway. [see comments]. Nat Immunol 2 9 (2001) 835
12. Horng T., Barton G.M., Flavell R.A., and Medzhitov R. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 420 6913 (2002) 329
13. Fitzgerald K.A., Palsson-McDermott E.M., Bowie A.G., et al. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 413 6851 (2001) 78
14. Kagan J.C., and Medzhitov R. Phosphoinositide-mediated adaptor recruitment controls toll-like receptor signaling. Cell 125 5 (2006) 943
15. Hoebe K., Du X., Georgel P., et al. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424 6950 (2003) 743
16. Hoebe K., Janssen E.M., Kim S.O., et al. Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat Immunol 4 12 (2003) 1223
17. Yamamoto M., Sato S., Hemmi H., et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301 5633 (2003) 640
18. Lund J.M., Alexopoulou L., Sato A., et al. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci U S A 101 15 (2004) 5598
19. Lund J., Sato A., Akira S., Medzhitov R., and Iwasaki A. Toll-like receptor 9-mediated recognition of herpes simplex virus-2 by plasmacytoid dendritic cells. J Exp Med 198 3 (2003) 513
20. Heil F., Hemmi H., Hochrein H., et al. Species-specific recognition of single-stranded rna via toll-like receptor 7 and 8. Science 303 5663 (2004) 1526
21. Yamamoto M., Sato S., Hemmi H., et al. TRAM is specifically involved in the toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat Immunol 4 11 (2003) 1144
22. O'Neill L.A.J., Fitzgerald K.A., and Bowie A.G. The toll-IL-1 receptor adaptor family grows to five members. Trends Immunol 24 6 (2003) 286
23. Schnare M., Barton G.M., Holt A.C., Takeda K., Akira S., and Medzhitov R. Toll-like receptors control activation of adaptive immune responses. Nat Immunol 2 10 (2001) 947
24. Jankovic D., Kullberg M.C., Hieny S., Caspar P., Collazo C.M., and Sher A. In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting. Immunity 16 3 (2002) 429
25. Redecke V., Hacker H., Datta S.K., et al. Cutting edge: activation of toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma. J Immunol 172 5 (2004) 2739
26. Supajatura V., Ushio H., Nakao A., et al. Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity. J Clin Invest 109 10 (2002) 1351
27. Kobayashi K., Hernandez L.D., Galan J.E., Janeway Jr. C.A., Medzhitov R., and Flavell R.A. IRAK-M is a negative regulator of toll-like receptor signaling. Cell 110 2 (2002) 191
28. Kinjyo I., Hanada T., Inagaki-Ohara K., et al. SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. Immunity 17 5 (2002) 583
29. Burns K., Janssens S., Brissoni B., Olivos N., Beyaert R., and Tschopp J. Inhibition of interleukin 1 receptor/toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J Exp Med 197 2 (2003) 263
30. Wald D., Qin J., Zhao Z., et al. SIGIRR, a negative regulator of toll-like receptor-interleukin 1 receptor signaling. Nat Immunol 4 9 (2003) 920
31. Boone D.L., Turer E.E., Lee E.G., et al. The ubiquitin-modifying enzyme A20 is required for termination of toll-like receptor responses. Nature 5 10 (2004) 1052
32. Weaver C.T., Harrington L.E., Mangan P.R., Gavrieli M., and Murphy K.M. Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 24 6 (2006) 677
33. Pasare C., and Medzhitov R. Toll pathway-dependent blockade of CD4 + CD25 + T cell-mediated suppression by dendritic cells. Science 299 5609 (2003) 1033
34. Caramalho I., Lopes-Carvalho T., Ostler D., Zelenay S., Haury M., and Demengeot J. Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med 197 4 (2003) 403
35. Netea M.G., Sutmuller R., Hermann C., et al. Toll-like receptor 2 suppresses immunity against candida albicans through induction of IL-10 and regulatory T cells. J Immunol 172 6 (2004) 3712
36. Liu H., Komai-Koma M., Xu D., Liew F.Y., et al. Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells. Proc Natl Acad Sci U S A 103 18 (2006) 7048
37. Peng G., Guo Z., Kiniwa Y., et al. Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Science 309 5739 (2005) 1380
38. Zanin-Zhorov A., Cahalon L., Tal G., Margalit R., Lider O., and Cohen I.R. Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling. J Clin Invest 116 7 (2006) 2022 [%R 10.1172/JCI28423]
39. Boros P., and Bromberg J.S. New cellular and molecular immune pathways in ischemia/reperfusion injury. Am J Transplant 6 4 (2006) 652
40. Zhai Y., Shen X.-d., O'Connell R., et al. Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J Immunol 173 12 (2004) 7115
41. Oyama J.-i., Blais Jr. C., Liu X., et al. Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice. Circulation 109 6 (2004) 784
42. Shishido T., Nozaki N., Yamaguchi S., et al. Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction. Circulation 108 23 (2003) 2905
43. Guillot L., Balloy V., McCormack F.X., Golenbock D.T., Chignard M., and Si-Tahar M. Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves toll-like receptor 4. J Immunol 168 12 (2002) 5989
44. Asea A., Kraeft S.K., Kurt-Jones E.A., et al. HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat Med 6 4 (2000) 435
45. Johnson G.B., Brunn G.J., Kodaira Y., and Platt J.L. Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by toll-like receptor 4. J Immunol 168 10 (2002) 5233
46. Ohashi K., Burkart V., Flohe S., and Kolb H. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 164 2 (2000) 558
47. Termeer C., Benedix F., Sleeman J., et al. Oligosaccharides of hyaluronan activate dendritic cells via toll-like receptor 4. J Exp Med 195 1 (2002) 99
48. Leadbetter E.A., Rifkin I.R., Hohlbaum A.M., Beaudette B.C., Shlomchik M.J., and Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and toll-like receptors. Nature 416 6881 (2002) 603
49. Rock K.L., Hearn A., Chen C.J., and YS. Natural endogenous adjuvants. Springer Semin Immunopathol 26 3 (2005) 231
50. Gaston J.S. Heat shock proteins and innate immunity.[comment]. Clin Exp Immunol 127 1 (2002) 1
51. Pockley A.G. Heat shock proteins, anti-heat shock protein reactivity and allograft rejection. Transplantation 71 11 (2001) 1503
52. Goldstein D.R., Tesar B.M., Akira S., and Lakkis F.G. Critical role of the toll-like receptor signal adaptor protein MyD88 in acute allograft rejection. J Clin Invest 111 10 (2003) 1571
53. Samstein B., Johnson G.B., and JL P. Toll-like receptor-4 and allograft responses. Transplantation 15 77 (2004) 475
54. Tesar B.M., Zhang J., Li Q., and Goldstein D.R. TH1 immune responses to fully MHC mismatched allografts are diminished in the absence of MyD88, a toll like receptor signal adaptor protein. Am J Transplant 4 9 (2004) 1429
55. Palmer S.M., Burch L.H., Davis R.D., et al. The role of innate immunity in acute allograft rejection after lung transplantation. Am J Respir Crit Care Med 168 6 (2003) 628
56. Palmer S.M., Burch L.H., Trindade A.J., et al. Innate immunity influences long-term outcomes after human lung transplant. Am J Respir Crit Care Med 171 7 (2005) 780
57. Ducloux D., Deschamps M., Yannaraki M., et al. Relevance of toll-like receptor-4 polymorphisms in renal transplantation. Kidney Int 67 6 (2005) 2454
58. Kiechl S., Lorenz E., Reindl M., et al. Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med 347 3 (2002) 185
59. Methe H., Zimmer E., Grimm C., Nabauer Ma., Koglin J., et al. Evidence for a Role of toll-like receptor 4 in development of chronic allograft rejection after cardiac transplantation. Transplantation 78 9 (1954) 1324