-
1
-
-
0141724605
-
The genetics of pancreatic cancer
-
Cowgill S.M., and Muscarella P. The genetics of pancreatic cancer. Am. J. Surg. 186 (2003) 279-286
-
(2003)
Am. J. Surg.
, vol.186
, pp. 279-286
-
-
Cowgill, S.M.1
Muscarella, P.2
-
2
-
-
0036883940
-
Pancreatic cancer biology and genetics
-
Bardeesy N., and DePinho R.A. Pancreatic cancer biology and genetics. Nat. Rev., Cancer 2 (2002) 897-909
-
(2002)
Nat. Rev., Cancer
, vol.2
, pp. 897-909
-
-
Bardeesy, N.1
DePinho, R.A.2
-
3
-
-
27744575208
-
Endocrine pancreatic tumors: factors correlated with survival
-
Tomassetti P., Campana D., Piscitelli L., Casadei R., Santini D., Nori F., Morselli-Labate A.M., Pezzilli R., and Corinaldesi R. Endocrine pancreatic tumors: factors correlated with survival. Ann. Oncol. 16 (2005) 1806-1810
-
(2005)
Ann. Oncol.
, vol.16
, pp. 1806-1810
-
-
Tomassetti, P.1
Campana, D.2
Piscitelli, L.3
Casadei, R.4
Santini, D.5
Nori, F.6
Morselli-Labate, A.M.7
Pezzilli, R.8
Corinaldesi, R.9
-
5
-
-
31744431998
-
Tumours of the endocrine pancreas
-
DeLellis R.A., Lloyd R.V., Heitz P.U., and Eng C. (Eds), IARC Press, Lyon
-
Heitz P.U., Komminoth P., Perren A., Klimstra D.S., and Dayal Y. Tumours of the endocrine pancreas. In: DeLellis R.A., Lloyd R.V., Heitz P.U., and Eng C. (Eds). Pathology and Genetics. Tumours of endocrine organs (2004), IARC Press, Lyon 177-208
-
(2004)
Pathology and Genetics. Tumours of endocrine organs
, pp. 177-208
-
-
Heitz, P.U.1
Komminoth, P.2
Perren, A.3
Klimstra, D.S.4
Dayal, Y.5
-
6
-
-
2342510386
-
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
-
Dor Y., Brown J., Martinez O.I., and Melton D.A. Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429 (2004) 41-46
-
(2004)
Nature
, vol.429
, pp. 41-46
-
-
Dor, Y.1
Brown, J.2
Martinez, O.I.3
Melton, D.A.4
-
7
-
-
33947497482
-
Multiple endocrine neoplasia type 1 (MEN1): loss of one MEN1 allele in tumors and monohormonal endocrine cell clusters but not in islet hyperplasia of the pancreas
-
Perren A., Anlauf M., Henopp T., Rudolph T., Schmitt A., Raffel A., Gimm O., Weihe E., Knoefel W.T., Dralle H., Heitz P.U., Komminoth P., and Klöppel G. Multiple endocrine neoplasia type 1 (MEN1): loss of one MEN1 allele in tumors and monohormonal endocrine cell clusters but not in islet hyperplasia of the pancreas. J. Clin. Endocrinol. Metab. 92 (2007) 1118-1128
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 1118-1128
-
-
Perren, A.1
Anlauf, M.2
Henopp, T.3
Rudolph, T.4
Schmitt, A.5
Raffel, A.6
Gimm, O.7
Weihe, E.8
Knoefel, W.T.9
Dralle, H.10
Heitz, P.U.11
Komminoth, P.12
Klöppel, G.13
-
8
-
-
27744558963
-
Endocrine tumors of the pancreas. Best practice and research
-
Oberg K., and Eriksson B. Endocrine tumors of the pancreas. Best practice and research. Clin. Gastroenterol. 19 (2005) 753-781
-
(2005)
Clin. Gastroenterol.
, vol.19
, pp. 753-781
-
-
Oberg, K.1
Eriksson, B.2
-
9
-
-
33745937110
-
Update on pancreatic endocrine tumors
-
Frankel W.L. Update on pancreatic endocrine tumors. Arch. Pathol. Lab. Med. 130 (2006) 963-966
-
(2006)
Arch. Pathol. Lab. Med.
, vol.130
, pp. 963-966
-
-
Frankel, W.L.1
-
10
-
-
0030748590
-
Novel pancreatic endocrine tumor suppressor gene locus on chromosome 3p with clinical prognostic implications
-
Chung D.C., Smith A.P., Louis D.N., Graeme-Cook F., Warshaw A.L., and Arnold A.A. Novel pancreatic endocrine tumor suppressor gene locus on chromosome 3p with clinical prognostic implications. J. Clin. Invest. 100 (1997) 404-410
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 404-410
-
-
Chung, D.C.1
Smith, A.P.2
Louis, D.N.3
Graeme-Cook, F.4
Warshaw, A.L.5
Arnold, A.A.6
-
11
-
-
0031872093
-
Multiple neuroendocrine tumors of the pancreas in von Hippel-Lindau disease patients: histopathological and molecular genetic analysis
-
Lubensky I.A., Pack S., Ault D., Vortmeyer A.O., Libutti S.K., Choyke P.L., Walther M.M., Linehan W.M., and Zhuang Z. Multiple neuroendocrine tumors of the pancreas in von Hippel-Lindau disease patients: histopathological and molecular genetic analysis. Am. J. Pathol. 153 (1998) 223-231
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 223-231
-
-
Lubensky, I.A.1
Pack, S.2
Ault, D.3
Vortmeyer, A.O.4
Libutti, S.K.5
Choyke, P.L.6
Walther, M.M.7
Linehan, W.M.8
Zhuang, Z.9
-
12
-
-
2342499096
-
Molecular genetics of gastroenteropancreatic endocrine tumors
-
Perren A., Komminoth P., and Heitz P.U. Molecular genetics of gastroenteropancreatic endocrine tumors. Ann. N. Y. Acad. Sci. 1014 (2004) 199-208
-
(2004)
Ann. N. Y. Acad. Sci.
, vol.1014
, pp. 199-208
-
-
Perren, A.1
Komminoth, P.2
Heitz, P.U.3
-
13
-
-
0033853351
-
Chromosomal alterations in human pancreatic endocrine tumors
-
Stumpf E., Aalto Y., Hoog A., Kjellman M., Otonkoski T., Knuutila S., and Andersson L.C. Chromosomal alterations in human pancreatic endocrine tumors. Genes Chromosomes Cancer 28 (2000) 83-87
-
(2000)
Genes Chromosomes Cancer
, vol.28
, pp. 83-87
-
-
Stumpf, E.1
Aalto, Y.2
Hoog, A.3
Kjellman, M.4
Otonkoski, T.5
Knuutila, S.6
Andersson, L.C.7
-
14
-
-
0032761852
-
Genetic differences in endocrine pancreatic tumor subtypes detected by comparative genomic hybridization
-
Speel E.J.M., Richter J., Moch H., Egenter C., Saremaslani P., Rutimann K., Zhao J., Barghorn A., Roth J., Heitz P.U., and Komminoth P. Genetic differences in endocrine pancreatic tumor subtypes detected by comparative genomic hybridization. Am. J. Pathol. 155 (1999) 1787-1794
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1787-1794
-
-
Speel, E.J.M.1
Richter, J.2
Moch, H.3
Egenter, C.4
Saremaslani, P.5
Rutimann, K.6
Zhao, J.7
Barghorn, A.8
Roth, J.9
Heitz, P.U.10
Komminoth, P.11
-
15
-
-
0035394330
-
Genetic evidence for early divergence of small functioning and nonfunctioning endocrine pancreatic tumors: gain of 9q34 is an early event in insulinomas
-
Speel E.J.M., Scheidweiler A.F., Zhao J., Matter C., Saremaslani P., Roth J., Heitz P.U., and Komminoth P. Genetic evidence for early divergence of small functioning and nonfunctioning endocrine pancreatic tumors: gain of 9q34 is an early event in insulinomas. Cancer Res. 61 (2001) 5186-5192
-
(2001)
Cancer Res.
, vol.61
, pp. 5186-5192
-
-
Speel, E.J.M.1
Scheidweiler, A.F.2
Zhao, J.3
Matter, C.4
Saremaslani, P.5
Roth, J.6
Heitz, P.U.7
Komminoth, P.8
-
16
-
-
0035172596
-
Genomic imbalances in the progression of endocrine pancreatic tumors
-
Zhao J., Moch H., Scheidweiler A.F., Baer A., Schäffer A.A., Speel E.J.M., Roth J., Heitz P.U., and Komminoth P. Genomic imbalances in the progression of endocrine pancreatic tumors. Genes Chromosomes Cancer 32 (2001) 364-372
-
(2001)
Genes Chromosomes Cancer
, vol.32
, pp. 364-372
-
-
Zhao, J.1
Moch, H.2
Scheidweiler, A.F.3
Baer, A.4
Schäffer, A.A.5
Speel, E.J.M.6
Roth, J.7
Heitz, P.U.8
Komminoth, P.9
-
17
-
-
0033555995
-
Deletion of chromosome 1 predicts prognosis in pancreatic endocrine tumors
-
Ebrahimi S.A., Wang E.H., Wu A., Schreck R.R., Passaro Jr. E., and Sawicki M.P. Deletion of chromosome 1 predicts prognosis in pancreatic endocrine tumors. Cancer Res. 59 (1999) 311-315
-
(1999)
Cancer Res.
, vol.59
, pp. 311-315
-
-
Ebrahimi, S.A.1
Wang, E.H.2
Wu, A.3
Schreck, R.R.4
Passaro Jr., E.5
Sawicki, M.P.6
-
18
-
-
0035138085
-
High resolution allelotype of non-functional pancreatic endocrine tumors: identification of two molecular subgroups with clinical implications
-
Rigaud G., Missiaglia E., Moore P.S., Zamboni G., Falconi M., Talamini G., Pesci A., Baron A., Lissandrini D., Rindi G., Grigolato P., Pederzoli P., and Scarpa A. High resolution allelotype of non-functional pancreatic endocrine tumors: identification of two molecular subgroups with clinical implications. Cancer Res. 61 (2001) 285-292
-
(2001)
Cancer Res.
, vol.61
, pp. 285-292
-
-
Rigaud, G.1
Missiaglia, E.2
Moore, P.S.3
Zamboni, G.4
Falconi, M.5
Talamini, G.6
Pesci, A.7
Baron, A.8
Lissandrini, D.9
Rindi, G.10
Grigolato, P.11
Pederzoli, P.12
Scarpa, A.13
-
19
-
-
0034868240
-
Deletion at 3p25.3-p23 is frequently encountered in endocrine pancreatic tumours and is associated with metastatic progression
-
Barghorn A., Komminoth P., Bachmann D., Rütimann K., Saremaslani P., Mulatta-Feurer S., Perren A., Roth J., Heitz P.U., and Speel E.J. Deletion at 3p25.3-p23 is frequently encountered in endocrine pancreatic tumours and is associated with metastatic progression. J. Pathol. 94 (2001) 451-458
-
(2001)
J. Pathol.
, vol.94
, pp. 451-458
-
-
Barghorn, A.1
Komminoth, P.2
Bachmann, D.3
Rütimann, K.4
Saremaslani, P.5
Mulatta-Feurer, S.6
Perren, A.7
Roth, J.8
Heitz, P.U.9
Speel, E.J.10
-
20
-
-
0032869951
-
Genetic alterations on 3p, 11q13, and 18q in nonfamilial and MEN1-associated pancreatic endocrine tumors
-
Hessman O., Lindberg D., Einarsson A., Lillhager P., Carling T., Grimelius L., Eriksson B., Akerstrom G., Westin G., and Skogseid B. Genetic alterations on 3p, 11q13, and 18q in nonfamilial and MEN1-associated pancreatic endocrine tumors. Genes Chromosomes Cancer 26 (1999) 258-264
-
(1999)
Genes Chromosomes Cancer
, vol.26
, pp. 258-264
-
-
Hessman, O.1
Lindberg, D.2
Einarsson, A.3
Lillhager, P.4
Carling, T.5
Grimelius, L.6
Eriksson, B.7
Akerstrom, G.8
Westin, G.9
Skogseid, B.10
-
21
-
-
0034843771
-
Role of disease-causing genes in sporadic pancreatic endocrine tumors: MEN1 and VHL
-
Moore P.S., Missiaglia E., Antonello D., Zamo A., Zamboni G., Corleto V., Falconi M., and Scarpa A. Role of disease-causing genes in sporadic pancreatic endocrine tumors: MEN1 and VHL. Genes Chromosomes Cancer 32 (2001) 177-181
-
(2001)
Genes Chromosomes Cancer
, vol.32
, pp. 177-181
-
-
Moore, P.S.1
Missiaglia, E.2
Antonello, D.3
Zamo, A.4
Zamboni, G.5
Corleto, V.6
Falconi, M.7
Scarpa, A.8
-
22
-
-
0034970550
-
Putative tumor suppressor loci at 6q22 and 6q23-q24 are involved in the malignant progression of sporadic endocrine pancreatic tumors
-
Barghorn A., Speel E.J.M., Farspour B., Saremaslani P., Schmid S., Perren A., Roth J., Heitz P.U., and Komminoth P. Putative tumor suppressor loci at 6q22 and 6q23-q24 are involved in the malignant progression of sporadic endocrine pancreatic tumors. Am. J. Pathol. 158 (2001) 1903-1911
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 1903-1911
-
-
Barghorn, A.1
Speel, E.J.M.2
Farspour, B.3
Saremaslani, P.4
Schmid, S.5
Perren, A.6
Roth, J.7
Heitz, P.U.8
Komminoth, P.9
-
23
-
-
0035156850
-
Pancreatic tumors: molecular pathways implicated in ductal cancer are involved in ampullary but not in exocrine nonductal or endocrine tumorigenesis
-
Moore P.S., Orlandini S., Zamboni G., Capelli P., Rigaud G., Falconi M., Bassi C., Lemoine N.R., and Scarpa A. Pancreatic tumors: molecular pathways implicated in ductal cancer are involved in ampullary but not in exocrine nonductal or endocrine tumorigenesis. Br. J. Cancer 84 (2001) 253-262
-
(2001)
Br. J. Cancer
, vol.84
, pp. 253-262
-
-
Moore, P.S.1
Orlandini, S.2
Zamboni, G.3
Capelli, P.4
Rigaud, G.5
Falconi, M.6
Bassi, C.7
Lemoine, N.R.8
Scarpa, A.9
-
24
-
-
85047676827
-
Alterations in the p16INK4a/CDKN2A tumor suppressor gene in gastrinomas
-
Serrano J., Goebel S.U., Peghini P.L., Lubensky I.A., Gibril F., and Jensen R.T. Alterations in the p16INK4a/CDKN2A tumor suppressor gene in gastrinomas. J. Clin. Endocrinol. Metab. 85 (2000) 4146-4156
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 4146-4156
-
-
Serrano, J.1
Goebel, S.U.2
Peghini, P.L.3
Lubensky, I.A.4
Gibril, F.5
Jensen, R.T.6
-
25
-
-
0033809990
-
Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells
-
Perren A., Komminoth P., Saremaslani P., Matter C., Feurer S., Lees J.A., Heitz P.U., and Eng C. Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells. Am. J. Pathol. 157 (2000) 1097-1103
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 1097-1103
-
-
Perren, A.1
Komminoth, P.2
Saremaslani, P.3
Matter, C.4
Feurer, S.5
Lees, J.A.6
Heitz, P.U.7
Eng, C.8
-
26
-
-
0034011833
-
Lack of MEN1 gene mutations in 27 sporadic insulinomas
-
Cupisti K., Hoppner W., Dotzenrath C., Simon D., Berndt I., Roher H.D., and Goretzki P.E. Lack of MEN1 gene mutations in 27 sporadic insulinomas. Eur. J. Clin. Invest. 30 (2000) 325-329
-
(2000)
Eur. J. Clin. Invest.
, vol.30
, pp. 325-329
-
-
Cupisti, K.1
Hoppner, W.2
Dotzenrath, C.3
Simon, D.4
Berndt, I.5
Roher, H.D.6
Goretzki, P.E.7
-
27
-
-
0344699339
-
Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to foregut neoplasms
-
Gortz B., Roth J., Krahenmann A., de Krijger R.R., Muletta-Feurer S., Rutimann K., Saremaslani P., Speel E.J., Heitz P.U., and Komminoth P. Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to foregut neoplasms. Am. J. Pathol. 154 (1999) 429-436
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 429-436
-
-
Gortz, B.1
Roth, J.2
Krahenmann, A.3
de Krijger, R.R.4
Muletta-Feurer, S.5
Rutimann, K.6
Saremaslani, P.7
Speel, E.J.8
Heitz, P.U.9
Komminoth, P.10
-
28
-
-
0032005227
-
Mutation of the multiple endocrine neoplasia type 1 gene in nonfamilial, malignant tumors of the endocrine pancreas
-
Hessman O., Lindberg D., Skogseid B., Carling T., Hellman P., Rastad J., Akerstrom G., and Westin G. Mutation of the multiple endocrine neoplasia type 1 gene in nonfamilial, malignant tumors of the endocrine pancreas. Cancer Res. 58 (1998) 377-379
-
(1998)
Cancer Res.
, vol.58
, pp. 377-379
-
-
Hessman, O.1
Lindberg, D.2
Skogseid, B.3
Carling, T.4
Hellman, P.5
Rastad, J.6
Akerstrom, G.7
Westin, G.8
-
29
-
-
0037168186
-
Absence of somatic SDHD mutations in sporadic neuroendocrine tumors and detection of two germline variants in paraganglioma patients
-
Perren A., Barghorn A., Schmid S., Saremaslani P., Roth J., Heitz P.U., and Komminoth P. Absence of somatic SDHD mutations in sporadic neuroendocrine tumors and detection of two germline variants in paraganglioma patients. Oncogene 21 (2002) 7605-7608
-
(2002)
Oncogene
, vol.21
, pp. 7605-7608
-
-
Perren, A.1
Barghorn, A.2
Schmid, S.3
Saremaslani, P.4
Roth, J.5
Heitz, P.U.6
Komminoth, P.7
-
30
-
-
0036348541
-
Mutational analysis of Smad3, a candidate tumor suppressor implicated in TGF-beta and menin pathways, in parathyroid adenomas and enteropancreatic endocrine tumors
-
Shattuck T.M., Costa J., Bernstein M., Jensen R.T., Chung D.C., and Arnold A. Mutational analysis of Smad3, a candidate tumor suppressor implicated in TGF-beta and menin pathways, in parathyroid adenomas and enteropancreatic endocrine tumors. J. Clin. Endocrinol. Metab. 87 (2002) 3911-3914
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 3911-3914
-
-
Shattuck, T.M.1
Costa, J.2
Bernstein, M.3
Jensen, R.T.4
Chung, D.C.5
Arnold, A.6
-
31
-
-
26544450568
-
DPC4/Smad4 expression is lost in a subset of ductal adenocarcinomas of the pancreas but not in endocrine pancreatic tumors and chronic pancreatitis
-
Perren A., Hurlimann S., Saremaslani P., Schmid S., Bonvin C., Roth J., Heitz P.U., and Komminoth P. DPC4/Smad4 expression is lost in a subset of ductal adenocarcinomas of the pancreas but not in endocrine pancreatic tumors and chronic pancreatitis. Mod. Pathol. 15 (2002) 119A
-
(2002)
Mod. Pathol.
, vol.15
-
-
Perren, A.1
Hurlimann, S.2
Saremaslani, P.3
Schmid, S.4
Bonvin, C.5
Roth, J.6
Heitz, P.U.7
Komminoth, P.8
-
32
-
-
0036772376
-
Chromosome 22q in pancreatic endocrine tumors: identification of a homozygous deletion and potential prognostic associations of allelic deletions
-
Wild A., Langer P., Celik I., Chaloupka B., and Bartsch D.K. Chromosome 22q in pancreatic endocrine tumors: identification of a homozygous deletion and potential prognostic associations of allelic deletions. Eur. J. Endocrinol. 147 (2002) 507-513
-
(2002)
Eur. J. Endocrinol.
, vol.147
, pp. 507-513
-
-
Wild, A.1
Langer, P.2
Celik, I.3
Chaloupka, B.4
Bartsch, D.K.5
-
33
-
-
0036533542
-
Sex chromosome anomalies in pancreatic endocrine tumors
-
Missiaglia E., Moore P.S., Williamson J., Lemoine N.R., Falconi M., Zamboni G., and Scarpa A. Sex chromosome anomalies in pancreatic endocrine tumors. Int. J. Cancer 98 (2002) 532-538
-
(2002)
Int. J. Cancer
, vol.98
, pp. 532-538
-
-
Missiaglia, E.1
Moore, P.S.2
Williamson, J.3
Lemoine, N.R.4
Falconi, M.5
Zamboni, G.6
Scarpa, A.7
-
34
-
-
0021732923
-
Metastatic insulin-secreting carcinoma of the pancreas: clinical course and the role of surgery
-
Danforth D.N., Gorden P., and Brennan M.F. Metastatic insulin-secreting carcinoma of the pancreas: clinical course and the role of surgery. Surgery 96 (1984) 1027-1037
-
(1984)
Surgery
, vol.96
, pp. 1027-1037
-
-
Danforth, D.N.1
Gorden, P.2
Brennan, M.F.3
-
35
-
-
20144362217
-
Persistent hyperinsulinemic hypoglycaemia in 15 adults with diffuse nesidioblastosis
-
Anlauf M., Wieben D., Perren A., Sipos B., Komminoth P., Raffel A., Kruse M.L., Fottner C., Knoefel W.T., Monig H., Heitz P.U., and Kloppel G. Persistent hyperinsulinemic hypoglycaemia in 15 adults with diffuse nesidioblastosis. Am. J. Surg. Pathol. 29 (2005) 524-533
-
(2005)
Am. J. Surg. Pathol.
, vol.29
, pp. 524-533
-
-
Anlauf, M.1
Wieben, D.2
Perren, A.3
Sipos, B.4
Komminoth, P.5
Raffel, A.6
Kruse, M.L.7
Fottner, C.8
Knoefel, W.T.9
Monig, H.10
Heitz, P.U.11
Kloppel, G.12
-
36
-
-
0033339417
-
Noninsulinoma pancreatogenous hypoglycaemia in adults independent of mutations in Kir6.2 and SUR1 genes
-
Service F.J., Natt N., Thompson G.B., Grant C.S., van Heerden J.A., Andrews J.C., Lorenz E., Terzic A., and Lloyd R.V. Noninsulinoma pancreatogenous hypoglycaemia in adults independent of mutations in Kir6.2 and SUR1 genes. J. Clin. Endocrinol. Metab. 84 (1999) 1582-1589
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 1582-1589
-
-
Service, F.J.1
Natt, N.2
Thompson, G.B.3
Grant, C.S.4
van Heerden, J.A.5
Andrews, J.C.6
Lorenz, E.7
Terzic, A.8
Lloyd, R.V.9
-
37
-
-
33646565292
-
Islet hyperplasia in adults: challenge to preoperatively diagnose non-insulinoma pancreatogenic hypoglycaemia syndrome
-
Starke A., Saddig C., Kirch B., Tschahargane C., and Goretzki P. Islet hyperplasia in adults: challenge to preoperatively diagnose non-insulinoma pancreatogenic hypoglycaemia syndrome. World J. Surg. 30 (2006) 1-10
-
(2006)
World J. Surg.
, vol.30
, pp. 1-10
-
-
Starke, A.1
Saddig, C.2
Kirch, B.3
Tschahargane, C.4
Goretzki, P.5
-
38
-
-
0026041670
-
The role of somatostatin and its analogs in the diagnosis and treatment of tumors
-
Lamberts S.W., Krenning E.P., and Reubi J.C. The role of somatostatin and its analogs in the diagnosis and treatment of tumors. Endocr. Rev. 12 (1991) 450-482
-
(1991)
Endocr. Rev.
, vol.12
, pp. 450-482
-
-
Lamberts, S.W.1
Krenning, E.P.2
Reubi, J.C.3
-
41
-
-
33749025798
-
Laparoscopic treatment of benign insulinomas localized in the body and tail of the pancreas: a single-center experience
-
Toniato A., Meduri F., Foletto M., Avogaro A., and Pelizzo M. Laparoscopic treatment of benign insulinomas localized in the body and tail of the pancreas: a single-center experience. World J. Surg. 30 (2006) 1916-1919
-
(2006)
World J. Surg.
, vol.30
, pp. 1916-1919
-
-
Toniato, A.1
Meduri, F.2
Foletto, M.3
Avogaro, A.4
Pelizzo, M.5
-
42
-
-
25444526452
-
Multimodality preoperative imaging of pancreatic insulinomas
-
McAuley G., Delaney H., Colville J., Lyburn I., Worsley D., Govender P., and Torreggiani W.C. Multimodality preoperative imaging of pancreatic insulinomas. Clin. Radiol. 60 (2005) 1039-1050
-
(2005)
Clin. Radiol.
, vol.60
, pp. 1039-1050
-
-
McAuley, G.1
Delaney, H.2
Colville, J.3
Lyburn, I.4
Worsley, D.5
Govender, P.6
Torreggiani, W.C.7
-
43
-
-
0026612352
-
Immunochemical investigation of insulinomas for islet amyloid polypeptide and insulin: evidence for differential synthesis and storage
-
Williams A.J., Coates P.J., Lowe D.G., McLean C., and Gale E.A. Immunochemical investigation of insulinomas for islet amyloid polypeptide and insulin: evidence for differential synthesis and storage. Histopathology 21 (1992) 215-223
-
(1992)
Histopathology
, vol.21
, pp. 215-223
-
-
Williams, A.J.1
Coates, P.J.2
Lowe, D.G.3
McLean, C.4
Gale, E.A.5
-
44
-
-
0021258390
-
Calcification in an insulinoma of the pancreas
-
Wolf E.L., Sprayregen S., Frager D., Rifkin H., and Gliedman M.L. Calcification in an insulinoma of the pancreas. Am. J. Gastroenterol. 79 (1984) 559-561
-
(1984)
Am. J. Gastroenterol.
, vol.79
, pp. 559-561
-
-
Wolf, E.L.1
Sprayregen, S.2
Frager, D.3
Rifkin, H.4
Gliedman, M.L.5
-
45
-
-
0027379560
-
Ultrastructural study of a black insulinoma
-
Illyes G., Bucsek M.J., Kadar A., Horanyi J., and Flautner L. Ultrastructural study of a black insulinoma. Ultrastruct. Pathol. 17 (1993) 495-501
-
(1993)
Ultrastruct. Pathol.
, vol.17
, pp. 495-501
-
-
Illyes, G.1
Bucsek, M.J.2
Kadar, A.3
Horanyi, J.4
Flautner, L.5
-
46
-
-
0033509238
-
Human insulinoma: clinical, cellular, and molecular aspects
-
Komminoth P., Heitz P.U., and Roth J. Human insulinoma: clinical, cellular, and molecular aspects. Endocr. Pathol. 10 (1999) 269-281
-
(1999)
Endocr. Pathol.
, vol.10
, pp. 269-281
-
-
Komminoth, P.1
Heitz, P.U.2
Roth, J.3
-
47
-
-
0027078707
-
Distribution patterns of proinsulin and insulin in human insulinomas: an immunohistochemical analysis in 76 tumors
-
Roth J., Kloppel G., Madsen O.D., Storch M.J., and Heitz P.U. Distribution patterns of proinsulin and insulin in human insulinomas: an immunohistochemical analysis in 76 tumors. Virchows Arch. 63 (1992) 51-61
-
(1992)
Virchows Arch.
, vol.63
, pp. 51-61
-
-
Roth, J.1
Kloppel, G.2
Madsen, O.D.3
Storch, M.J.4
Heitz, P.U.5
-
50
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
51
-
-
21244446206
-
Chromosomal instability predicts metastatic disease in patients with insulinomas
-
Jonkers Y.M.H., Claessen S.M.H., Perren A., Schmid S., Komminoth P., Verhofstad A.A., Hofland L.J., de Krijger R.R., Slootweg P.J., Ramaekers F.C.S., and Speel E.J.M. Chromosomal instability predicts metastatic disease in patients with insulinomas. Endocr. Relat. Cancer 12 (2005) 435-447
-
(2005)
Endocr. Relat. Cancer
, vol.12
, pp. 435-447
-
-
Jonkers, Y.M.H.1
Claessen, S.M.H.2
Perren, A.3
Schmid, S.4
Komminoth, P.5
Verhofstad, A.A.6
Hofland, L.J.7
de Krijger, R.R.8
Slootweg, P.J.9
Ramaekers, F.C.S.10
Speel, E.J.M.11
-
52
-
-
33751504040
-
Novel candidate tumor suppressor gene loci on chromosomes 11q23-24 and 22q13 involved in human insulinoma tumorigenesis
-
Jonkers Y.M.H., Claessen S.M.H., Feuth T., Geurts van Kessel A., Ramaekers F.C.S., Veltman J.A., and Speel E.J.M. Novel candidate tumor suppressor gene loci on chromosomes 11q23-24 and 22q13 involved in human insulinoma tumorigenesis. J. Pathol. 210 (2006) 450-458
-
(2006)
J. Pathol.
, vol.210
, pp. 450-458
-
-
Jonkers, Y.M.H.1
Claessen, S.M.H.2
Feuth, T.3
Geurts van Kessel, A.4
Ramaekers, F.C.S.5
Veltman, J.A.6
Speel, E.J.M.7
-
53
-
-
33751539392
-
Molecular parameters associated with insulinoma progression: chromosomal instability versus p53 and CK19 status
-
Jonkers Y.M.H., Claessen S.M.H., Veltman J.A., Geurts van Kessel A., Dinjens W.N.M., Skogseid B., Ramaekers F.C.S., and Speel E.J.M. Molecular parameters associated with insulinoma progression: chromosomal instability versus p53 and CK19 status. Cytogenet. Genome Res. 115 (2006) 289-297
-
(2006)
Cytogenet. Genome Res.
, vol.115
, pp. 289-297
-
-
Jonkers, Y.M.H.1
Claessen, S.M.H.2
Veltman, J.A.3
Geurts van Kessel, A.4
Dinjens, W.N.M.5
Skogseid, B.6
Ramaekers, F.C.S.7
Speel, E.J.M.8
-
54
-
-
0028876097
-
Multiple genetic alterations in malignant metastatic insulinomas
-
Pavelic K., Hrascan R., Kapitanovic S., Karapandza N., Vranes Z., Belicza M., Kruslin B., and Cabrijan T. Multiple genetic alterations in malignant metastatic insulinomas. J. Pathol. 177 (1995) 395-400
-
(1995)
J. Pathol.
, vol.177
, pp. 395-400
-
-
Pavelic, K.1
Hrascan, R.2
Kapitanovic, S.3
Karapandza, N.4
Vranes, Z.5
Belicza, M.6
Kruslin, B.7
Cabrijan, T.8
-
55
-
-
4644364498
-
Functional interaction between tumor suppressor menin and activator of S-phase kinase
-
Schnepp R.W., Hou Z., Wang H., Petersen C., Silva A., Masai H., and Hua X. Functional interaction between tumor suppressor menin and activator of S-phase kinase. Cancer Res. 64 (2004) 6791-6796
-
(2004)
Cancer Res.
, vol.64
, pp. 6791-6796
-
-
Schnepp, R.W.1
Hou, Z.2
Wang, H.3
Petersen, C.4
Silva, A.5
Masai, H.6
Hua, X.7
-
56
-
-
26844548626
-
Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27KIP1 and p18INK4C
-
Karnik S.K., Hughes C.M., Gu X., Rozenblatt-Rosen O., McLean G.W., Xiong Y., Meyerson M., and Kim S.K. Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27KIP1 and p18INK4C. Proc. Natl. Acad. Sci. 102 (2005) 14659-14664
-
(2005)
Proc. Natl. Acad. Sci.
, vol.102
, pp. 14659-14664
-
-
Karnik, S.K.1
Hughes, C.M.2
Gu, X.3
Rozenblatt-Rosen, O.4
McLean, G.W.5
Xiong, Y.6
Meyerson, M.7
Kim, S.K.8
-
57
-
-
33745238921
-
Mutation of tumor suppressor gene MEN1 acutely enhances proliferation of pancreatic islet cells
-
Schnepp R.W., Chen Y.X., Wang H., Cash T., Silva A., Diehl J.A., Brown E., and Hua X. Mutation of tumor suppressor gene MEN1 acutely enhances proliferation of pancreatic islet cells. Cancer Res. 66 (2006) 5707-5715
-
(2006)
Cancer Res.
, vol.66
, pp. 5707-5715
-
-
Schnepp, R.W.1
Chen, Y.X.2
Wang, H.3
Cash, T.4
Silva, A.5
Diehl, J.A.6
Brown, E.7
Hua, X.8
-
58
-
-
0034752757
-
p27: A potential main inhibitor of cell proliferation in digestive endocrine tumors but not a marker of benign behaviour
-
Canavese G., Azzoni C., Pizzi S., Corleto V., Pasquali C., Davoli C., Crafa P., Delle Fave G., and Bordi C. p27: A potential main inhibitor of cell proliferation in digestive endocrine tumors but not a marker of benign behaviour. Human Pathol. 32 (2001) 1094-1101
-
(2001)
Human Pathol.
, vol.32
, pp. 1094-1101
-
-
Canavese, G.1
Azzoni, C.2
Pizzi, S.3
Corleto, V.4
Pasquali, C.5
Davoli, C.6
Crafa, P.7
Delle Fave, G.8
Bordi, C.9
-
59
-
-
11844262698
-
Cyclin-dependent kinase (cdk6) and p16 in pancreatic endocrine neoplasms
-
Tomita T. Cyclin-dependent kinase (cdk6) and p16 in pancreatic endocrine neoplasms. Pathology 36 (2004) 566-570
-
(2004)
Pathology
, vol.36
, pp. 566-570
-
-
Tomita, T.1
-
60
-
-
0033766944
-
Low frequency of p16 (INK4a) alterations in insulinomas
-
Bartch D.K., Kersting M., Wild A., Ramaswamy A., Gerdes B., Schuermann M., Simon B., and Rothmund M. Low frequency of p16 (INK4a) alterations in insulinomas. Digestion 62 (2000) 171-177
-
(2000)
Digestion
, vol.62
, pp. 171-177
-
-
Bartch, D.K.1
Kersting, M.2
Wild, A.3
Ramaswamy, A.4
Gerdes, B.5
Schuermann, M.6
Simon, B.7
Rothmund, M.8
-
61
-
-
0035421265
-
Tumor suppressor genes in the 9p21 gene cluster are selective targets of inactivation in neuroendocrine gastroenteropancreatic tumors
-
Lubomierski N., Kersting M., Bert T., Muench K., Wulbrand U., Schuermann M., Bartsch D., and Simon B. Tumor suppressor genes in the 9p21 gene cluster are selective targets of inactivation in neuroendocrine gastroenteropancreatic tumors. Cancer Res. 61 (2001) 5905-5910
-
(2001)
Cancer Res.
, vol.61
, pp. 5905-5910
-
-
Lubomierski, N.1
Kersting, M.2
Bert, T.3
Muench, K.4
Wulbrand, U.5
Schuermann, M.6
Bartsch, D.7
Simon, B.8
-
62
-
-
2442419535
-
Transfection of the multiple endocrine neoplasia type 1 gene to a human endocrine pancreatic tumor cell line inhibits cell growth and affects expression of JunD, (-like protein 1/preadipocyte factor-1, proliferating cell nuclear antigen, and QM/Jif-1
-
Stalberg P., Grimfjard P., Santesson M., Zhou Y., Lindberg D., Gobl A., Oberg K., Westin G., Rastad J., Wang S., and Skogseid B. Transfection of the multiple endocrine neoplasia type 1 gene to a human endocrine pancreatic tumor cell line inhibits cell growth and affects expression of JunD, (-like protein 1/preadipocyte factor-1, proliferating cell nuclear antigen, and QM/Jif-1. J. Clin. Endocrinol. Metab. 89 (2004) 2326-2337
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 2326-2337
-
-
Stalberg, P.1
Grimfjard, P.2
Santesson, M.3
Zhou, Y.4
Lindberg, D.5
Gobl, A.6
Oberg, K.7
Westin, G.8
Rastad, J.9
Wang, S.10
Skogseid, B.11
-
63
-
-
0034534019
-
Overexpression of cyclin D1 occurs frequently in human pancreatic endocrine tumors
-
Chung D.C., Brown S.B., Graeme-Cook F., Seto M., Warshaw A.L., Jensen R.T., and Arnold A. Overexpression of cyclin D1 occurs frequently in human pancreatic endocrine tumors. J. Clin. Endocrinol. Metab. 85 (2000) 4373-4378
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 4373-4378
-
-
Chung, D.C.1
Brown, S.B.2
Graeme-Cook, F.3
Seto, M.4
Warshaw, A.L.5
Jensen, R.T.6
Arnold, A.7
-
64
-
-
0142182100
-
Frequent overexpression of cyclin D1 in sporadic pancreatic endocrine tumors
-
Guo S.S., Wu X., Shimoide A.T., Wong J., Moatamed F., and Sawicki M.P. Frequent overexpression of cyclin D1 in sporadic pancreatic endocrine tumors. J. Endocrinol. 179 (2003) 73-79
-
(2003)
J. Endocrinol.
, vol.179
, pp. 73-79
-
-
Guo, S.S.1
Wu, X.2
Shimoide, A.T.3
Wong, J.4
Moatamed, F.5
Sawicki, M.P.6
-
65
-
-
33644754585
-
Akt induces β-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity
-
Fatrai S., Elghazi L., Balcazar N., Cras-Meneur C., Krits I., Kiyokawa H., and Bernal-Mizrachi E. Akt induces β-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity. Diabetes 55 (2006) 318-325
-
(2006)
Diabetes
, vol.55
, pp. 318-325
-
-
Fatrai, S.1
Elghazi, L.2
Balcazar, N.3
Cras-Meneur, C.4
Krits, I.5
Kiyokawa, H.6
Bernal-Mizrachi, E.7
-
66
-
-
3042589472
-
Gene expression profiling in human insulinoma tissue: genes involved in the insulin secretion pathway and cloning of novel full-length cDNAs
-
Wang X.C., Xu S.Y., Wu X.Y., Song H.D., Mao Y.F., Fan H.Y., Yu F., Mou B., Gu Y.Y., Xu L.Q., Zhou X.O., Chen Z., Chen J.L., and Hu R.M. Gene expression profiling in human insulinoma tissue: genes involved in the insulin secretion pathway and cloning of novel full-length cDNAs. Endocr. Relat. Cancer 11 (2004) 295-303
-
(2004)
Endocr. Relat. Cancer
, vol.11
, pp. 295-303
-
-
Wang, X.C.1
Xu, S.Y.2
Wu, X.Y.3
Song, H.D.4
Mao, Y.F.5
Fan, H.Y.6
Yu, F.7
Mou, B.8
Gu, Y.Y.9
Xu, L.Q.10
Zhou, X.O.11
Chen, Z.12
Chen, J.L.13
Hu, R.M.14
-
67
-
-
0024435665
-
Attenuated processing of epidermal growth factor in the face of marked degradation of transforming growth factor-alpha
-
Korc M., and Finman J.E. Attenuated processing of epidermal growth factor in the face of marked degradation of transforming growth factor-alpha. J. Biol. Chem. 264 (1989) 14990-14999
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 14990-14999
-
-
Korc, M.1
Finman, J.E.2
-
68
-
-
0033841640
-
Co-expression of epidermal growth factor and transforming growth factor-alpha is independent of ras mutations in lung adenocarcinoma
-
Hsieh E.T., Shepherd F.A., and Tsao M.S. Co-expression of epidermal growth factor and transforming growth factor-alpha is independent of ras mutations in lung adenocarcinoma. Lung Cancer 29 (2000) 151-157
-
(2000)
Lung Cancer
, vol.29
, pp. 151-157
-
-
Hsieh, E.T.1
Shepherd, F.A.2
Tsao, M.S.3
-
69
-
-
0030957902
-
Expression of mixed lineage kinase-1 in pancreatic β-cell lines at different stages of maturation and during embryonic pancreas development
-
DeAizpurua H.J., Cram D.S., Naselli G., Devereux L., and Dorow D.S. Expression of mixed lineage kinase-1 in pancreatic β-cell lines at different stages of maturation and during embryonic pancreas development. J. Biol. Chem. 272 (1997) 16364-16373
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16364-16373
-
-
DeAizpurua, H.J.1
Cram, D.S.2
Naselli, G.3
Devereux, L.4
Dorow, D.S.5
-
72
-
-
0026811209
-
Co-deletions of the retinoblastoma gene and Wilms' tumor gene and rearrangement of the Krev-1 gene in a human insulinoma
-
Iwamura Y., Futagawa T., Kaneko M., Nahagawa K., Kawai K., Yamashita K., Nakamura T., and Hayashi H. Co-deletions of the retinoblastoma gene and Wilms' tumor gene and rearrangement of the Krev-1 gene in a human insulinoma. Jpn. J. Clin. Oncol. 22 (1992) 6-9
-
(1992)
Jpn. J. Clin. Oncol.
, vol.22
, pp. 6-9
-
-
Iwamura, Y.1
Futagawa, T.2
Kaneko, M.3
Nahagawa, K.4
Kawai, K.5
Yamashita, K.6
Nakamura, T.7
Hayashi, H.8
-
73
-
-
0030725466
-
Analysis of the retinoblastoma tumor suppressor gene in pancreatic endocrine tumors
-
Chung D.C., Smith A.P., Louis D.N., Graeme-Cook F., Warshaw A.L., and Arnold A. Analysis of the retinoblastoma tumor suppressor gene in pancreatic endocrine tumors. Clin. Endocrinol. 47 (1997) 523-528
-
(1997)
Clin. Endocrinol.
, vol.47
, pp. 523-528
-
-
Chung, D.C.1
Smith, A.P.2
Louis, D.N.3
Graeme-Cook, F.4
Warshaw, A.L.5
Arnold, A.6
-
74
-
-
0028937476
-
Mice deficient in both p53 and Rb develop tumors primarily of endocrine origin
-
Harvey M., Vogel H., Lee E.Y.H.P., Bradley A., and Donehower L.A. Mice deficient in both p53 and Rb develop tumors primarily of endocrine origin. Cancer Res. 55 (1995) 1146-1151
-
(1995)
Cancer Res.
, vol.55
, pp. 1146-1151
-
-
Harvey, M.1
Vogel, H.2
Lee, E.Y.H.P.3
Bradley, A.4
Donehower, L.A.5
-
75
-
-
33745030531
-
Essential role of PTEN in body size determination and pancreatic β-cell homeostasis in vivo
-
Nguyen K.T.T., Tajmir P., Lin C.H., Liadis N., Zhu X.D., Eweida M., Tolasa-Karaman G., Cai F., Wang R., Kitamura T., Belsham D.D., Wheeler M.B., Suzuki A., Mak T.W., and Woo M. Essential role of PTEN in body size determination and pancreatic β-cell homeostasis in vivo. Mol. Cell. Biol. 26 (2006) 4511-4518
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 4511-4518
-
-
Nguyen, K.T.T.1
Tajmir, P.2
Lin, C.H.3
Liadis, N.4
Zhu, X.D.5
Eweida, M.6
Tolasa-Karaman, G.7
Cai, F.8
Wang, R.9
Kitamura, T.10
Belsham, D.D.11
Wheeler, M.B.12
Suzuki, A.13
Mak, T.W.14
Woo, M.15
-
76
-
-
4444222528
-
Raf kinase inhibitory protein inhibits β-cell proliferation
-
Zhang L., Fu Z., Binkley C., Giordano T., Burant C.F., Logsdon C.D., and Simeone D.M. Raf kinase inhibitory protein inhibits β-cell proliferation. Surgery 136 (2004) 708-715
-
(2004)
Surgery
, vol.136
, pp. 708-715
-
-
Zhang, L.1
Fu, Z.2
Binkley, C.3
Giordano, T.4
Burant, C.F.5
Logsdon, C.D.6
Simeone, D.M.7
-
77
-
-
0030810185
-
Somatic mutations of the MEN1 tumor suppressor gene in sporadic gastrinomas and insulinomas
-
Zhuang Z., Vortmeyer A.O., Pack S., Huang S., Pham T.A., Wang C., Park W.S., Agarwal S.K., Debelenko L.V., Kester M., Guru S.C., Manickam P., Olufemi S.E., Yu F., Heppner C., Crabtree J.S., Skarulis M.C., Venzon D.J., Emmert-Buck M.R., Spiegel A.M., Chandrasekharappa S.C., Collins F.S., Burns A.L., Marx S.J., Jensen R.T., Liotta L.A., and Lubensky I.A. Somatic mutations of the MEN1 tumor suppressor gene in sporadic gastrinomas and insulinomas. Cancer Res. 57 (1997) 4682-4686
-
(1997)
Cancer Res.
, vol.57
, pp. 4682-4686
-
-
Zhuang, Z.1
Vortmeyer, A.O.2
Pack, S.3
Huang, S.4
Pham, T.A.5
Wang, C.6
Park, W.S.7
Agarwal, S.K.8
Debelenko, L.V.9
Kester, M.10
Guru, S.C.11
Manickam, P.12
Olufemi, S.E.13
Yu, F.14
Heppner, C.15
Crabtree, J.S.16
Skarulis, M.C.17
Venzon, D.J.18
Emmert-Buck, M.R.19
Spiegel, A.M.20
Chandrasekharappa, S.C.21
Collins, F.S.22
Burns, A.L.23
Marx, S.J.24
Jensen, R.T.25
Liotta, L.A.26
Lubensky, I.A.27
more..
-
79
-
-
0042440941
-
Pancreatic β-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice
-
Bertolino P., Tong W.M., Herrera P.L., Casse H., Zhang C.X., and Wang Z.Q. Pancreatic β-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice. Cancer Res. 63 (2003) 4836-4841
-
(2003)
Cancer Res.
, vol.63
, pp. 4836-4841
-
-
Bertolino, P.1
Tong, W.M.2
Herrera, P.L.3
Casse, H.4
Zhang, C.X.5
Wang, Z.Q.6
-
80
-
-
0041970059
-
Of mice and MEN1: insulinomas in a conditional mouse knockout
-
Crabtree J.S., Scacheri P.C., Ward J.M., McNally S.R., Swain G.P., Montagna C., Hager J.H., Hanahan D., Edlund H., Magnuson M.A., Garrett-Beal L., Burns A.L., Ried T., Chandrasekharappa S.C., Marx S.J., Spiegel A.M., and Collins F.S. Of mice and MEN1: insulinomas in a conditional mouse knockout. Mol. Cell. Biol. 23 (2003) 6075-6085
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6075-6085
-
-
Crabtree, J.S.1
Scacheri, P.C.2
Ward, J.M.3
McNally, S.R.4
Swain, G.P.5
Montagna, C.6
Hager, J.H.7
Hanahan, D.8
Edlund, H.9
Magnuson, M.A.10
Garrett-Beal, L.11
Burns, A.L.12
Ried, T.13
Chandrasekharappa, S.C.14
Marx, S.J.15
Spiegel, A.M.16
Collins, F.S.17
-
81
-
-
0030436420
-
Lack of p53 immunoreactivity in pancreatic endocrine tumors
-
Lee C.S. Lack of p53 immunoreactivity in pancreatic endocrine tumors. Pathology 28 (1996) 139-141
-
(1996)
Pathology
, vol.28
, pp. 139-141
-
-
Lee, C.S.1
-
82
-
-
0043175232
-
Menin associates with FANCD2, a protein involved in repair of DNA damage
-
Jin S., Mao H., Schnepp R.W., Sykes S.M., Silva A.C., D'Andrea A.D., and Hua X. Menin associates with FANCD2, a protein involved in repair of DNA damage. Cancer Res. 63 (2003) 4204-4210
-
(2003)
Cancer Res.
, vol.63
, pp. 4204-4210
-
-
Jin, S.1
Mao, H.2
Schnepp, R.W.3
Sykes, S.M.4
Silva, A.C.5
D'Andrea, A.D.6
Hua, X.7
-
83
-
-
0030842534
-
Oncogene expression in gastroenteropancreatic neuroendocrine tumors. Implications for pathogenesis
-
Wang D.G., Johnston C.F., and Buchanan K.D. Oncogene expression in gastroenteropancreatic neuroendocrine tumors. Implications for pathogenesis. Cancer 80 (1997) 668-675
-
(1997)
Cancer
, vol.80
, pp. 668-675
-
-
Wang, D.G.1
Johnston, C.F.2
Buchanan, K.D.3
-
84
-
-
2942739033
-
BRCC2, a novel BH3-like domain-containing protein, induces apoptosis in a caspase-dependent manner
-
Broustas C.G., Gokhale P.C., Rahman A., Dritschilo A., Ahmad I., and Kasid U. BRCC2, a novel BH3-like domain-containing protein, induces apoptosis in a caspase-dependent manner. J. Biol. Chem. 279 (2004) 26780-26788
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26780-26788
-
-
Broustas, C.G.1
Gokhale, P.C.2
Rahman, A.3
Dritschilo, A.4
Ahmad, I.5
Kasid, U.6
-
85
-
-
0030812331
-
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
-
Kaghad M., Bonnet H., Yang A., Creancier L., Biscan J.C., Valent A., Minty A., Chalon P., Lelias J.M., Dumont X., Ferrara P., McKeon F., and Caput D. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 90 (1997) 809-819
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
Creancier, L.4
Biscan, J.C.5
Valent, A.6
Minty, A.7
Chalon, P.8
Lelias, J.M.9
Dumont, X.10
Ferrara, P.11
McKeon, F.12
Caput, D.13
-
86
-
-
0025204548
-
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
-
Hockenbery D., Nunez G., Milliman C., Schreiber R.D., and Korsmeyer S.J. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348 (1990) 334-336
-
(1990)
Nature
, vol.348
, pp. 334-336
-
-
Hockenbery, D.1
Nunez, G.2
Milliman, C.3
Schreiber, R.D.4
Korsmeyer, S.J.5
-
87
-
-
20944440677
-
Nuclear survivin is a powerful novel prognostic marker in gastroenteropancreatic neuroendocrine tumor disease
-
Grabowski P., Griss S., Arnold C.N., Horsch D., Goke R., Arnold R., Heine B., Stein H., Zeitz M., and Scherubl H. Nuclear survivin is a powerful novel prognostic marker in gastroenteropancreatic neuroendocrine tumor disease. Neuroendocrinology 81 (2005) 1-9
-
(2005)
Neuroendocrinology
, vol.81
, pp. 1-9
-
-
Grabowski, P.1
Griss, S.2
Arnold, C.N.3
Horsch, D.4
Goke, R.5
Arnold, R.6
Heine, B.7
Stein, H.8
Zeitz, M.9
Scherubl, H.10
-
88
-
-
33645473185
-
Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells
-
Wang Z., Zhang Y., Li Y., Banerjee S., Liao J., and Sarkar F.H. Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells. Mol. Cancer Ther. 5 (2006) 483-493
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 483-493
-
-
Wang, Z.1
Zhang, Y.2
Li, Y.3
Banerjee, S.4
Liao, J.5
Sarkar, F.H.6
-
89
-
-
17944367982
-
The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation
-
Heppner C., Bilimoria K.Y., Agarwal S.K., Kester M., Whitty L.J., Guru S.C., Chandrasekharappa S.C., Collins F.S., Spiegel A.M., Marx S.J., and Burns A.L. The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation. Oncogene 20 (2001) 4917-4925
-
(2001)
Oncogene
, vol.20
, pp. 4917-4925
-
-
Heppner, C.1
Bilimoria, K.Y.2
Agarwal, S.K.3
Kester, M.4
Whitty, L.J.5
Guru, S.C.6
Chandrasekharappa, S.C.7
Collins, F.S.8
Spiegel, A.M.9
Marx, S.J.10
Burns, A.L.11
-
90
-
-
0037821661
-
Multiple tumor suppressor pathways negatively regulate telomerase
-
Lin S.Y., and Elledge S.J. Multiple tumor suppressor pathways negatively regulate telomerase. Cell 113 (2003) 881-889
-
(2003)
Cell
, vol.113
, pp. 881-889
-
-
Lin, S.Y.1
Elledge, S.J.2
-
91
-
-
0026495364
-
Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors
-
Kallioniemi A., Kallioniemi O.P., Sudar D., Rutovitz D., Gray J.W., Waldman F., and Pinkel D. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science 258 (1992) 818-821
-
(1992)
Science
, vol.258
, pp. 818-821
-
-
Kallioniemi, A.1
Kallioniemi, O.P.2
Sudar, D.3
Rutovitz, D.4
Gray, J.W.5
Waldman, F.6
Pinkel, D.7
-
92
-
-
23444459574
-
Array CGH technologies and their applications to cancer genomes
-
Davies J.J., Wilson I.M., and Lam W.L. Array CGH technologies and their applications to cancer genomes. Chromosome Res. 13 (2005) 237-248
-
(2005)
Chromosome Res.
, vol.13
, pp. 237-248
-
-
Davies, J.J.1
Wilson, I.M.2
Lam, W.L.3
-
93
-
-
20044375763
-
Array comparative genomic hybridization and its applications in cancer
-
Pinkel D., and Albertson D.G. Array comparative genomic hybridization and its applications in cancer. Nat. Genet. 37 (2005) 11-17
-
(2005)
Nat. Genet.
, vol.37
, pp. 11-17
-
-
Pinkel, D.1
Albertson, D.G.2
-
94
-
-
0036731786
-
Review of the clinical, histological, and molecular aspects of pancreatic endocrine neoplasms
-
Gumbs A.A., Moore P.S., Falconi M., Bassi C., Beghelli S., Modlin I., and Scarpa A. Review of the clinical, histological, and molecular aspects of pancreatic endocrine neoplasms. J. Surg. Oncol. 81 (2002) 45-53
-
(2002)
J. Surg. Oncol.
, vol.81
, pp. 45-53
-
-
Gumbs, A.A.1
Moore, P.S.2
Falconi, M.3
Bassi, C.4
Beghelli, S.5
Modlin, I.6
Scarpa, A.7
-
95
-
-
0037434786
-
CpG island methylation in carcinoid and pancreatic endocrine tumors
-
Chan A.O., Kim S.G., Bedeir A., Issa J.P., Hamilton S.R., and Rashid A. CpG island methylation in carcinoid and pancreatic endocrine tumors. Oncogene 22 (2003) 924-934
-
(2003)
Oncogene
, vol.22
, pp. 924-934
-
-
Chan, A.O.1
Kim, S.G.2
Bedeir, A.3
Issa, J.P.4
Hamilton, S.R.5
Rashid, A.6
-
96
-
-
0038695861
-
Functional studies of the MEN1 gene
-
Chandrasekharappa S.C., and The B.T. Functional studies of the MEN1 gene. J. Int. Med. 253 (2003) 606-615
-
(2003)
J. Int. Med.
, vol.253
, pp. 606-615
-
-
Chandrasekharappa, S.C.1
The, B.T.2
-
97
-
-
0028922623
-
Chromosomal instability in multiple endocrine neoplasia type 1
-
Tomassetti P., Cometa G., Del Vecchio E., Baserga M., Faccioli P., Bosoni D., Paolucci G., and Barbara L. Chromosomal instability in multiple endocrine neoplasia type 1. Cancer Genet. Cytogenet. 79 (1995) 123-126
-
(1995)
Cancer Genet. Cytogenet.
, vol.79
, pp. 123-126
-
-
Tomassetti, P.1
Cometa, G.2
Del Vecchio, E.3
Baserga, M.4
Faccioli, P.5
Bosoni, D.6
Paolucci, G.7
Barbara, L.8
-
98
-
-
0035044340
-
Multiple allelic deletions and intratumoral genetic heterogeneity in MEN1 pancreatic tumors
-
Hessman O., Skogseid B., Westin G., and Akerstrom G. Multiple allelic deletions and intratumoral genetic heterogeneity in MEN1 pancreatic tumors. J. Clin. Endocrinol. Metab. 86 (2001) 1355-1361
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1355-1361
-
-
Hessman, O.1
Skogseid, B.2
Westin, G.3
Akerstrom, G.4
-
99
-
-
0033864297
-
Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity
-
Franklin D.S., Godfrey V.L., O'Brien D.A., Deng C., and Xiong Y. Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity. Mol. Cell. Biol. 20 (2000) 6147-6158
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6147-6158
-
-
Franklin, D.S.1
Godfrey, V.L.2
O'Brien, D.A.3
Deng, C.4
Xiong, Y.5
-
100
-
-
33750361636
-
Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans
-
Pellegata N.S., Quintanilla-Martinez L., Siggelkow H., Samson E., Bink K., Hofler H., Fend F., Graw J., and Atkinson M.J. Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans. Proc. Natl. Acad. Sci. 103 (2006) 15558-15563
-
(2006)
Proc. Natl. Acad. Sci.
, vol.103
, pp. 15558-15563
-
-
Pellegata, N.S.1
Quintanilla-Martinez, L.2
Siggelkow, H.3
Samson, E.4
Bink, K.5
Hofler, H.6
Fend, F.7
Graw, J.8
Atkinson, M.J.9
-
101
-
-
27944477357
-
Epigenetic alterations in neuroendocrine tumors: methylation of RAS-association domain family 1, isoform A and p16 genes are associated with metastasis
-
Liu L., Broaddus R.R., Yao J.C., Xie S.S., White J.A., Wu T.T., Hamilton S.R., and Rashid A. Epigenetic alterations in neuroendocrine tumors: methylation of RAS-association domain family 1, isoform A and p16 genes are associated with metastasis. Mod. Pathol. 18 (2005) 1632-1640
-
(2005)
Mod. Pathol.
, vol.18
, pp. 1632-1640
-
-
Liu, L.1
Broaddus, R.R.2
Yao, J.C.3
Xie, S.S.4
White, J.A.5
Wu, T.T.6
Hamilton, S.R.7
Rashid, A.8
-
102
-
-
0035803395
-
Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors
-
Sotillo R., Dubus P., Martin J., dela Cueva E., Ortega S., Malumbres M., and Barbacid M. Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors. EMBO J. 20 (2001) 6637-6647
-
(2001)
EMBO J.
, vol.20
, pp. 6637-6647
-
-
Sotillo, R.1
Dubus, P.2
Martin, J.3
dela Cueva, E.4
Ortega, S.5
Malumbres, M.6
Barbacid, M.7
-
103
-
-
0041352090
-
Activating point mutations in cyclin-dependent kinase 4 are not seen in sporadic pituitary adenomas, insulinomas or Leydig cell tumors
-
Vax V.V., Bibi R., Diaz-Cano S., Gueorguiev M., Kola B., Borboli N., Bressac-de Paillerets B., Walker G.J., Dedov I.I., Grossman A.B., and Korbonits M. Activating point mutations in cyclin-dependent kinase 4 are not seen in sporadic pituitary adenomas, insulinomas or Leydig cell tumors. J. Endocrinol. 178 (2003) 301-310
-
(2003)
J. Endocrinol.
, vol.178
, pp. 301-310
-
-
Vax, V.V.1
Bibi, R.2
Diaz-Cano, S.3
Gueorguiev, M.4
Kola, B.5
Borboli, N.6
Bressac-de Paillerets, B.7
Walker, G.J.8
Dedov, I.I.9
Grossman, A.B.10
Korbonits, M.11
-
104
-
-
0037352170
-
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy
-
Chang F., Lee J.T., Navolanic P.M., Steelman L.S., Shelton J.G., Blalock W.L., Franklin R.A., and McCubrey J.A. Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia 17 (2003) 590-603
-
(2003)
Leukemia
, vol.17
, pp. 590-603
-
-
Chang, F.1
Lee, J.T.2
Navolanic, P.M.3
Steelman, L.S.4
Shelton, J.G.5
Blalock, W.L.6
Franklin, R.A.7
McCubrey, J.A.8
-
105
-
-
0033852721
-
mRNA expression patterns of insulin-like growth factor system components in human neuroendocrine tumors
-
Wulbrand U., Remmert G., Zofel P., Wied M., Arnold R., and Fehmann H.C. mRNA expression patterns of insulin-like growth factor system components in human neuroendocrine tumors. Eur. J. Clin. Invest. 30 (2000) 729-739
-
(2000)
Eur. J. Clin. Invest.
, vol.30
, pp. 729-739
-
-
Wulbrand, U.1
Remmert, G.2
Zofel, P.3
Wied, M.4
Arnold, R.5
Fehmann, H.C.6
-
106
-
-
0034662634
-
Insulin-like growth factor-1 is an autocrine regulator of chromogranin A secretion and growth in human neuroendocrine tumor cells
-
von Wichert G., Jehle P.M., Hoeflich A., Koschnick S., Dralle H., Wolf E., Wiedenmann B., Boehm B.O., Adler G., and Seufferlein T. Insulin-like growth factor-1 is an autocrine regulator of chromogranin A secretion and growth in human neuroendocrine tumor cells. Cancer Res. 60 (2000) 4573-4581
-
(2000)
Cancer Res.
, vol.60
, pp. 4573-4581
-
-
von Wichert, G.1
Jehle, P.M.2
Hoeflich, A.3
Koschnick, S.4
Dralle, H.5
Wolf, E.6
Wiedenmann, B.7
Boehm, B.O.8
Adler, G.9
Seufferlein, T.10
-
107
-
-
3042554112
-
Tumor suppressor menin regulates expression of insulin-like growth factor binding protein 2
-
La P., Schnepp R.W., Petersen C.D., Silva A.C., and Hua X. Tumor suppressor menin regulates expression of insulin-like growth factor binding protein 2. Endocrinology 145 (2004) 3443-3450
-
(2004)
Endocrinology
, vol.145
, pp. 3443-3450
-
-
La, P.1
Schnepp, R.W.2
Petersen, C.D.3
Silva, A.C.4
Hua, X.5
-
108
-
-
33846435771
-
Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic β cells and human islets. Involvement of cAMP/PKA, ERK1/2 and PI3K/AKT signalling
-
Granata R., Settani F., Biancone L., Trovato L., Nano R., Bertuzzi F., Destefanis S., Annunziata M., Martinetti M., Catapano F., Ghe C., Isgaard J., Papotti M., Ghigo E., and Muccioli G. Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic β cells and human islets. Involvement of cAMP/PKA, ERK1/2 and PI3K/AKT signalling. Endocrinology 148 (2007) 512-529
-
(2007)
Endocrinology
, vol.148
, pp. 512-529
-
-
Granata, R.1
Settani, F.2
Biancone, L.3
Trovato, L.4
Nano, R.5
Bertuzzi, F.6
Destefanis, S.7
Annunziata, M.8
Martinetti, M.9
Catapano, F.10
Ghe, C.11
Isgaard, J.12
Papotti, M.13
Ghigo, E.14
Muccioli, G.15
-
109
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402 (1999) 656-660
-
(1999)
Nature
, vol.402
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
Nakazato, M.4
Matsuo, H.5
Kangawa, K.6
-
110
-
-
0033867587
-
Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide
-
Tomasetto C., Karam S.M., Ribieras S., Masson R., Lefebvre O., Staub A., Alexander G., Chenard M.P., and Rio M.C. Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide. Gastroenterology 119 (2000) 395-405
-
(2000)
Gastroenterology
, vol.119
, pp. 395-405
-
-
Tomasetto, C.1
Karam, S.M.2
Ribieras, S.3
Masson, R.4
Lefebvre, O.5
Staub, A.6
Alexander, G.7
Chenard, M.P.8
Rio, M.C.9
-
111
-
-
1542267814
-
Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development
-
Prado C.L., Pugh-Bernard A.E., Elghazi L., Sosa-Pineda B., and Sussel L. Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 2924-2929
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 2924-2929
-
-
Prado, C.L.1
Pugh-Bernard, A.E.2
Elghazi, L.3
Sosa-Pineda, B.4
Sussel, L.5
-
112
-
-
33845654500
-
Co-expression of ghrelin and its receptor in pancreatic endocrine tumors
-
Ekeblad S., Lejonklou M.H., Grimfjard P., Johansson T., Eriksson B., Grimelius L., Stridsberg M., Stalberg P., and Skogseid B. Co-expression of ghrelin and its receptor in pancreatic endocrine tumors. Clin. Endocrinol. 66 (2007) 115-122
-
(2007)
Clin. Endocrinol.
, vol.66
, pp. 115-122
-
-
Ekeblad, S.1
Lejonklou, M.H.2
Grimfjard, P.3
Johansson, T.4
Eriksson, B.5
Grimelius, L.6
Stridsberg, M.7
Stalberg, P.8
Skogseid, B.9
-
113
-
-
0036959760
-
Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumors
-
Volante M., Allia E., Gugliotta P., Funaro A., Broglio F., Deghenghi R., Muccioli G., Ghigo E., and Papotti M. Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumors. J. Clin. Endocrinol. Metab. 87 (2002) 1300-1308
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 1300-1308
-
-
Volante, M.1
Allia, E.2
Gugliotta, P.3
Funaro, A.4
Broglio, F.5
Deghenghi, R.6
Muccioli, G.7
Ghigo, E.8
Papotti, M.9
-
114
-
-
34250207799
-
The Rap1/B-Raf signalling complex is a putative therapeutic target in neuroendocrine tumors of the digestive tract
-
(abstract B10)
-
Schrader J., Arnold R., and Horsch D. The Rap1/B-Raf signalling complex is a putative therapeutic target in neuroendocrine tumors of the digestive tract. Neuroendocrinology 83 (2006) 57 (abstract B10)
-
(2006)
Neuroendocrinology
, vol.83
, pp. 57
-
-
Schrader, J.1
Arnold, R.2
Horsch, D.3
-
115
-
-
0034673297
-
Signaling through the p38 and p42/44 mitogen-activated families of protein kinases in pancreatic β cell proliferation
-
Burns C.I., Squires P.E., and Persuad S.I. Signaling through the p38 and p42/44 mitogen-activated families of protein kinases in pancreatic β cell proliferation. Biochem. Biophys. Res. Commun. 268 (2000) 541-546
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.268
, pp. 541-546
-
-
Burns, C.I.1
Squires, P.E.2
Persuad, S.I.3
-
116
-
-
0031590853
-
Leptin induces proliferation of pancreatic cell line MIN6 through activation of mitogen-activated protein kinase
-
Tanabe K., Okuya S., Tanizawa Y., Matsutani A., and Oka Y. Leptin induces proliferation of pancreatic cell line MIN6 through activation of mitogen-activated protein kinase. Biochem. Biophys. Res. Commun. 241 (1997) 765-768
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.241
, pp. 765-768
-
-
Tanabe, K.1
Okuya, S.2
Tanizawa, Y.3
Matsutani, A.4
Oka, Y.5
-
117
-
-
0026457022
-
Ras mutations in endocrine tumors: mutation detection by polymerase chain reaction-single strand conformation polymorphism
-
Yoshimoto K., Iwahana H., Fukuda A., Sano T., Katsuragi K., Kinoshita M., Saito S., and Itakura M. Ras mutations in endocrine tumors: mutation detection by polymerase chain reaction-single strand conformation polymorphism. Jpn. J. Cancer Res. 83 (1992) 1057-1062
-
(1992)
Jpn. J. Cancer Res.
, vol.83
, pp. 1057-1062
-
-
Yoshimoto, K.1
Iwahana, H.2
Fukuda, A.3
Sano, T.4
Katsuragi, K.5
Kinoshita, M.6
Saito, S.7
Itakura, M.8
-
118
-
-
0027443009
-
Comparison of mutations of ras oncogene in human pancreatic exocrine and endocrine tumors
-
Yashiro T., Fulton N., Hara H., Yasudo K., Montag A., Yashiro N., Straus II F., Ito K., Aiyoshi Y., and Kaplan E.L. Comparison of mutations of ras oncogene in human pancreatic exocrine and endocrine tumors. Surgery 114 (1993) 758-763
-
(1993)
Surgery
, vol.114
, pp. 758-763
-
-
Yashiro, T.1
Fulton, N.2
Hara, H.3
Yasudo, K.4
Montag, A.5
Yashiro, N.6
Straus II, F.7
Ito, K.8
Aiyoshi, Y.9
Kaplan, E.L.10
-
119
-
-
11244304215
-
BRAF and endocrine tumors: mutations are frequent in papillary thyroid carcinomas, rare in endocrine tumors of the gastrointestinal tract and not detected in other endocrine tumors
-
Perren A., Schmid S., Locher T., Saremaslani P., Bonvin C., Heitz P.U., and Komminoth P. BRAF and endocrine tumors: mutations are frequent in papillary thyroid carcinomas, rare in endocrine tumors of the gastrointestinal tract and not detected in other endocrine tumors. Endocr. Relat. Cancer 11 (2004) 855-860
-
(2004)
Endocr. Relat. Cancer
, vol.11
, pp. 855-860
-
-
Perren, A.1
Schmid, S.2
Locher, T.3
Saremaslani, P.4
Bonvin, C.5
Heitz, P.U.6
Komminoth, P.7
-
120
-
-
13244284719
-
BRAF gene mutations are rare events in gastroenteropancreatic neuroendocrine tumors
-
Tannapfel A., Vomschloss S., Karhoff D., Markwarth A., Hengge U.R., Wittekind C., Arnold R., and Horsch D. BRAF gene mutations are rare events in gastroenteropancreatic neuroendocrine tumors. Am. J. Clin. Pathol. 123 (2005) 256-260
-
(2005)
Am. J. Clin. Pathol.
, vol.123
, pp. 256-260
-
-
Tannapfel, A.1
Vomschloss, S.2
Karhoff, D.3
Markwarth, A.4
Hengge, U.R.5
Wittekind, C.6
Arnold, R.7
Horsch, D.8
-
121
-
-
0024404145
-
GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumors
-
Landis C.A., Masters S.B., Spada A., Pace A.M., Bourne H.R., and Vallar L. GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumors. Nature 340 (1989) 692-696
-
(1989)
Nature
, vol.340
, pp. 692-696
-
-
Landis, C.A.1
Masters, S.B.2
Spada, A.3
Pace, A.M.4
Bourne, H.R.5
Vallar, L.6
-
122
-
-
0025127424
-
Two G protein oncogenes in human endocrine tumors
-
Lyons J., Landis C.A., Harsh G., Vallar L., Grunewald K., Feichtinger H., Duh Q.Y., Clark O.H., Kawasaki E., Bourne H.R., et al. Two G protein oncogenes in human endocrine tumors. Science 249 (1990) 655-659
-
(1990)
Science
, vol.249
, pp. 655-659
-
-
Lyons, J.1
Landis, C.A.2
Harsh, G.3
Vallar, L.4
Grunewald, K.5
Feichtinger, H.6
Duh, Q.Y.7
Clark, O.H.8
Kawasaki, E.9
Bourne, H.R.10
-
123
-
-
0025865247
-
Gsp mutations in human thyroid tumors
-
Suarez H.G., Duvillard J.A., Caillu B., Schlumberger M., Parmentier C., and Monier R. Gsp mutations in human thyroid tumors. Oncogene 6 (1991) 677-679
-
(1991)
Oncogene
, vol.6
, pp. 677-679
-
-
Suarez, H.G.1
Duvillard, J.A.2
Caillu, B.3
Schlumberger, M.4
Parmentier, C.5
Monier, R.6
-
124
-
-
0028148560
-
Absence of mutations in the Gsα Gi2α genes in sporadic parathyroid adenomas and insulinomas
-
Vessey S.J.R., Jones P.M., Wallis S.C., Schofield J., and Bloom S.R. Absence of mutations in the Gsα Gi2α genes in sporadic parathyroid adenomas and insulinomas. Clin. Sci. 87 (1994) 493-497
-
(1994)
Clin. Sci.
, vol.87
, pp. 493-497
-
-
Vessey, S.J.R.1
Jones, P.M.2
Wallis, S.C.3
Schofield, J.4
Bloom, S.R.5
-
125
-
-
0027181092
-
Gs alpha-identification of a gene highly expressed by insulinoma and other endocrine tumors
-
Zeiger M.A., and Norton J.A. Gs alpha-identification of a gene highly expressed by insulinoma and other endocrine tumors. Surgery 114 (1993) 458-463
-
(1993)
Surgery
, vol.114
, pp. 458-463
-
-
Zeiger, M.A.1
Norton, J.A.2
-
126
-
-
9444297268
-
Molecular genetics of malignant insulinoma
-
Pavelic K., Hrascan R., Kapitanovic S., Vranes Z., Cabrijan T., Spaventi S., Korsic M., Krizanac S., Li Y.Q., Stambrook P., Gluckman J.L., and Pavelic Z.P. Molecular genetics of malignant insulinoma. Anticancer Res. 16 (1996) 1707-1717
-
(1996)
Anticancer Res.
, vol.16
, pp. 1707-1717
-
-
Pavelic, K.1
Hrascan, R.2
Kapitanovic, S.3
Vranes, Z.4
Cabrijan, T.5
Spaventi, S.6
Korsic, M.7
Krizanac, S.8
Li, Y.Q.9
Stambrook, P.10
Gluckman, J.L.11
Pavelic, Z.P.12
-
127
-
-
25144432015
-
Epidermal growth factor receptor and activated epidermal growth factor receptor expression in gastrointestinal carcinoids and pancreatic endocrine carcinomas
-
Papouchado B., Erickson L.A., Rohlinger A.L., Hobday T.J., Erlichman C., Ames M.M., and Lloyd R.V. Epidermal growth factor receptor and activated epidermal growth factor receptor expression in gastrointestinal carcinoids and pancreatic endocrine carcinomas. Mod. Pathol. 18 (2005) 1329-1335
-
(2005)
Mod. Pathol.
, vol.18
, pp. 1329-1335
-
-
Papouchado, B.1
Erickson, L.A.2
Rohlinger, A.L.3
Hobday, T.J.4
Erlichman, C.5
Ames, M.M.6
Lloyd, R.V.7
-
128
-
-
0141528828
-
Chronic myeloid leukemia - advances in biology and new approaches to treatment
-
Goldman J.M., and Melo J.V. Chronic myeloid leukemia - advances in biology and new approaches to treatment. N. Engl. J. Med. 349 (2003) 1451-1464
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 1451-1464
-
-
Goldman, J.M.1
Melo, J.V.2
-
129
-
-
4444306013
-
The Rb network
-
DeGregory J. The Rb network. J. Cell Sci. 117 (2004) 3411-3413
-
(2004)
J. Cell Sci.
, vol.117
, pp. 3411-3413
-
-
DeGregory, J.1
-
130
-
-
31544445793
-
Rb plays a role in survival of Abl-dependent human tumor cells as a downstream effector of Abl tyrosine kinase
-
Nagano K., Itagaki C., Izumi T., Nunomura K., Soda Y., Tani K., Takahashi N., Takenawa T., and Isobe T. Rb plays a role in survival of Abl-dependent human tumor cells as a downstream effector of Abl tyrosine kinase. Oncogene 25 (2006) 493-502
-
(2006)
Oncogene
, vol.25
, pp. 493-502
-
-
Nagano, K.1
Itagaki, C.2
Izumi, T.3
Nunomura, K.4
Soda, Y.5
Tani, K.6
Takahashi, N.7
Takenawa, T.8
Isobe, T.9
-
131
-
-
0031984215
-
Genetic alterations in gastrinomas and nonfunctioning pancreatic neuroendocrine tumors: an analysis of p16/MTS1 tumor suppressor gene inactivation
-
Muscarella P., Melvin W.S., Fisher W.E., Foor J., Ellison E.C., Herman J.G., Schirmer W.J., Hitchcock C.L., De Young B.R., and Weghorst C.M. Genetic alterations in gastrinomas and nonfunctioning pancreatic neuroendocrine tumors: an analysis of p16/MTS1 tumor suppressor gene inactivation. Cancer Res. 58 (1998) 237-240
-
(1998)
Cancer Res.
, vol.58
, pp. 237-240
-
-
Muscarella, P.1
Melvin, W.S.2
Fisher, W.E.3
Foor, J.4
Ellison, E.C.5
Herman, J.G.6
Schirmer, W.J.7
Hitchcock, C.L.8
De Young, B.R.9
Weghorst, C.M.10
-
132
-
-
33744920617
-
Molecular control of cell cycle progression in the pancreatic β-cell
-
Cozar-Castellano I., Fiaschi-Taesch N., Bigatel T.A., Takane K.K., Garcia-Ocana A., Vasavada R., and Stewart A.F. Molecular control of cell cycle progression in the pancreatic β-cell. Endocr. Rev. 27 (2006) 356-370
-
(2006)
Endocr. Rev.
, vol.27
, pp. 356-370
-
-
Cozar-Castellano, I.1
Fiaschi-Taesch, N.2
Bigatel, T.A.3
Takane, K.K.4
Garcia-Ocana, A.5
Vasavada, R.6
Stewart, A.F.7
-
133
-
-
34250166621
-
WHO 2004 criteria and CK19 are reliable prognostic markers in pancreatic endocrine tumors
-
in press
-
Schmitt A.M., Anlauf M., Rousson V., Schmid S., Kofler A., Riniker F., Bauersfeld J., Barghorn A., Probst N., Moch H., Heitz P.U., Kloppel G., Komminoth P., and Perren A. WHO 2004 criteria and CK19 are reliable prognostic markers in pancreatic endocrine tumors. Am. J. Surg. Pathol. (2007) in press
-
(2007)
Am. J. Surg. Pathol.
-
-
Schmitt, A.M.1
Anlauf, M.2
Rousson, V.3
Schmid, S.4
Kofler, A.5
Riniker, F.6
Bauersfeld, J.7
Barghorn, A.8
Probst, N.9
Moch, H.10
Heitz, P.U.11
Kloppel, G.12
Komminoth, P.13
Perren, A.14
-
134
-
-
33644909083
-
Analysis of p27KIP1 expression in insulinomas developed in pancreatic β-cell specific MEN1 mutant mice
-
Fontaniere S., Casse H., Bertolino P., and Zhang C.X. Analysis of p27KIP1 expression in insulinomas developed in pancreatic β-cell specific MEN1 mutant mice. Familial Cancer 5 (2006) 49-54
-
(2006)
Familial Cancer
, vol.5
, pp. 49-54
-
-
Fontaniere, S.1
Casse, H.2
Bertolino, P.3
Zhang, C.X.4
-
135
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
Stambolic V., Suzuki A., de la Pompa J.L., Brothers G.M., Mirtsos C., Sasaki T., Ruland J., Penninger J.M., Siderovski P.P., and Mak T.W. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 95 (1998) 29-39
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
de la Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Ruland, J.7
Penninger, J.M.8
Siderovski, P.P.9
Mak, T.W.10
-
136
-
-
0035666843
-
Oncogenic co-operation in β-cell tumorigenesis
-
Pelengaris S., and Khan M. Oncogenic co-operation in β-cell tumorigenesis. Endocr. Relat. Cancer 8 (2001) 307-314
-
(2001)
Endocr. Relat. Cancer
, vol.8
, pp. 307-314
-
-
Pelengaris, S.1
Khan, M.2
-
137
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T., and Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80 (1995) 293-299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
138
-
-
0029003501
-
Wild-type p53 and a temperature-sensitive mutant induce Fas/Apo-1 expression
-
Owen-Schaub L.B., Zhang W., and Cusack J.C. Wild-type p53 and a temperature-sensitive mutant induce Fas/Apo-1 expression. Mol. Cell. Biol. 15 (1995) 3032-3040
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3032-3040
-
-
Owen-Schaub, L.B.1
Zhang, W.2
Cusack, J.C.3
-
139
-
-
0028171968
-
Mediation of c-Myc-induced apoptosis by p53
-
Hermeking H., and Eick D. Mediation of c-Myc-induced apoptosis by p53. Science 265 (1994) 2091-2093
-
(1994)
Science
, vol.265
, pp. 2091-2093
-
-
Hermeking, H.1
Eick, D.2
-
140
-
-
0036636869
-
Deletion of chromosome 1, but not mutation of MEN1 predicts prognosis in sporadic pancreatic endocrine tumors
-
Guo S.S., Wu A.Y., and Sawicki M.P. Deletion of chromosome 1, but not mutation of MEN1 predicts prognosis in sporadic pancreatic endocrine tumors. World J. Surg. 26 (2002) 843-847
-
(2002)
World J. Surg.
, vol.26
, pp. 843-847
-
-
Guo, S.S.1
Wu, A.Y.2
Sawicki, M.P.3
-
141
-
-
0033152429
-
Telomerase and the maintenance of chromosome ends
-
Bryan T.M., and Cech T.R. Telomerase and the maintenance of chromosome ends. Curr. Opin. Cell Biol. 11 (1999) 318-324
-
(1999)
Curr. Opin. Cell Biol.
, vol.11
, pp. 318-324
-
-
Bryan, T.M.1
Cech, T.R.2
-
142
-
-
0036120241
-
Telomerase activity in pancreatic endocrine tumors
-
Tang S.J., Dumot J.A., Wang L., Memmesheimer C., Conwell D.L., Zuccaro G., Goormastic M., Ormsby A.H., and Cowell J. Telomerase activity in pancreatic endocrine tumors. Am. J. Gastroenterol. 97 (2002) 1022-1030
-
(2002)
Am. J. Gastroenterol.
, vol.97
, pp. 1022-1030
-
-
Tang, S.J.1
Dumot, J.A.2
Wang, L.3
Memmesheimer, C.4
Conwell, D.L.5
Zuccaro, G.6
Goormastic, M.7
Ormsby, A.H.8
Cowell, J.9
-
143
-
-
0034091371
-
Telomerase activity in pancreatic endocrine tumors: a potential marker for malignancy
-
Lam K.Y., Lo C.Y., Fan S.T., and Luk J.M. Telomerase activity in pancreatic endocrine tumors: a potential marker for malignancy. Mol. Pathol. 53 (2000) 132-136
-
(2000)
Mol. Pathol.
, vol.53
, pp. 132-136
-
-
Lam, K.Y.1
Lo, C.Y.2
Fan, S.T.3
Luk, J.M.4
-
144
-
-
0141594629
-
Low microvessel density is an unfavourable histoprognostic factor in pancreatic endocrine tumors
-
Marion-Audibert A.M., Barel C., Gouysse G., Dumortier J., Pilleul F., Pourreyron C., Hervieu V., Poncet G., Lombard-Bohas C., Chayvialle J.A., Partensky C., and Scoazec J.Y. Low microvessel density is an unfavourable histoprognostic factor in pancreatic endocrine tumors. Gastroenterology 125 (2003) 1094-1104
-
(2003)
Gastroenterology
, vol.125
, pp. 1094-1104
-
-
Marion-Audibert, A.M.1
Barel, C.2
Gouysse, G.3
Dumortier, J.4
Pilleul, F.5
Pourreyron, C.6
Hervieu, V.7
Poncet, G.8
Lombard-Bohas, C.9
Chayvialle, J.A.10
Partensky, C.11
Scoazec, J.Y.12
-
145
-
-
19944434272
-
Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumors: negative correlation of microvascular density and VEGF expression with tumor progression
-
Couvelard A., O'Toole D., Turley H., Leek R., Sauvanet A., Degott C., Ruszniewski P., Belghiti J., Harris A.L., Gatter K., and Pezzella F. Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumors: negative correlation of microvascular density and VEGF expression with tumor progression. Br. J. Cancer 92 (2005) 94-101
-
(2005)
Br. J. Cancer
, vol.92
, pp. 94-101
-
-
Couvelard, A.1
O'Toole, D.2
Turley, H.3
Leek, R.4
Sauvanet, A.5
Degott, C.6
Ruszniewski, P.7
Belghiti, J.8
Harris, A.L.9
Gatter, K.10
Pezzella, F.11
-
146
-
-
12944315074
-
Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis
-
Schwarte-Waldhoff I., Volpert O.V., Bouck N.P., Sipos B., Hahn S.A., Klein-Scory S., Luttges J., Kloppel G., Graeven U., Eilert-Micus C., Hintelmann A., and Schmiegel W. Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis. Proc. Natl. Acad. Sci. 97 (2000) 9624-9629
-
(2000)
Proc. Natl. Acad. Sci.
, vol.97
, pp. 9624-9629
-
-
Schwarte-Waldhoff, I.1
Volpert, O.V.2
Bouck, N.P.3
Sipos, B.4
Hahn, S.A.5
Klein-Scory, S.6
Luttges, J.7
Kloppel, G.8
Graeven, U.9
Eilert-Micus, C.10
Hintelmann, A.11
Schmiegel, W.12
-
147
-
-
0033535531
-
Mutations of the DPC4/Smad4 gene in neuroendocrine pancreatic tumors
-
Bartsch D., Hahn S.A., Danichevski K.D., Ramaswamy A., Bastian D., Galehdari H., Barth P., Schmiegel W., Simon B., and Rothmund M. Mutations of the DPC4/Smad4 gene in neuroendocrine pancreatic tumors. Oncogene 18 (1999) 2367-2371
-
(1999)
Oncogene
, vol.18
, pp. 2367-2371
-
-
Bartsch, D.1
Hahn, S.A.2
Danichevski, K.D.3
Ramaswamy, A.4
Bastian, D.5
Galehdari, H.6
Barth, P.7
Schmiegel, W.8
Simon, B.9
Rothmund, M.10
-
148
-
-
0025805031
-
Cell adhesion molecules of the immunoglobulin supergene family and their role in malignant transformation and progression to metastatic disease
-
Johnson J.P. Cell adhesion molecules of the immunoglobulin supergene family and their role in malignant transformation and progression to metastatic disease. Cancer Metastasis Rev. 10 (1991) 11-22
-
(1991)
Cancer Metastasis Rev.
, vol.10
, pp. 11-22
-
-
Johnson, J.P.1
-
149
-
-
0029868605
-
The neural cell adhesion molecule NCAM in multiple myeloma
-
Kaiser U., Auerbach B., and Oldenburg M. The neural cell adhesion molecule NCAM in multiple myeloma. Leuk. Lymphoma 20 (1996) 389-395
-
(1996)
Leuk. Lymphoma
, vol.20
, pp. 389-395
-
-
Kaiser, U.1
Auerbach, B.2
Oldenburg, M.3
-
150
-
-
0030894177
-
Neural cell adhesion molecule (N-CAM) in gastrointestinal neoplasias
-
Fogar P., Basso D., Pasquali C., De Paoli M., Sperti C., Roveroni G., Pedrazzoli S., and Plebani M. Neural cell adhesion molecule (N-CAM) in gastrointestinal neoplasias. Anticancer Res. 17 (1997) 1227-1230
-
(1997)
Anticancer Res.
, vol.17
, pp. 1227-1230
-
-
Fogar, P.1
Basso, D.2
Pasquali, C.3
De Paoli, M.4
Sperti, C.5
Roveroni, G.6
Pedrazzoli, S.7
Plebani, M.8
-
151
-
-
0032978138
-
Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic β tumor cells
-
Perl A.K., Dahl U., Wilgenbus P., Cremer H., Semb H., and Christofori G. Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic β tumor cells. Nat. Med. 5 (1999) 286-291
-
(1999)
Nat. Med.
, vol.5
, pp. 286-291
-
-
Perl, A.K.1
Dahl, U.2
Wilgenbus, P.3
Cremer, H.4
Semb, H.5
Christofori, G.6
-
152
-
-
0032222421
-
Prognostic value of beta 1,6-branched oligosaccharides in human colorectal carcinoma
-
Seelentag W.K., Li W.P., Schmitz S.F., Metzger U., Aeberhard P., Heitz P.U., and Roth J. Prognostic value of beta 1,6-branched oligosaccharides in human colorectal carcinoma. Cancer Res. 58 (1998) 5559-55564
-
(1998)
Cancer Res.
, vol.58
, pp. 5559-55564
-
-
Seelentag, W.K.1
Li, W.P.2
Schmitz, S.F.3
Metzger, U.4
Aeberhard, P.5
Heitz, P.U.6
Roth, J.7
-
153
-
-
0029844138
-
Can malignancy in insulinoma be predicted by the expression of patterns of beta 1,6 branching of aspargine-linked oligosaccharides and polysialic acid of the neural cell adhesion molecule?
-
Li W.P., Komminoth P., Zuber C., Kloppel G., Heitz P.U., and Roth J. Can malignancy in insulinoma be predicted by the expression of patterns of beta 1,6 branching of aspargine-linked oligosaccharides and polysialic acid of the neural cell adhesion molecule?. Virchows Arch. 429 (1996) 197-204
-
(1996)
Virchows Arch.
, vol.429
, pp. 197-204
-
-
Li, W.P.1
Komminoth, P.2
Zuber, C.3
Kloppel, G.4
Heitz, P.U.5
Roth, J.6
-
154
-
-
0032510494
-
A causal role for E-cadherin in the transition from adenoma to carcinoma
-
Perl A.K., Wilgenbus P., Dahl U., Semb H., and Christofori G. A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 392 (1998) 190-193
-
(1998)
Nature
, vol.392
, pp. 190-193
-
-
Perl, A.K.1
Wilgenbus, P.2
Dahl, U.3
Semb, H.4
Christofori, G.5
-
155
-
-
16544366235
-
CD44 in cancer progression: adhesion, migration and growth regulation
-
Marhaba R., and Zoller M. CD44 in cancer progression: adhesion, migration and growth regulation. J. Mol. Histol. 35 (2004) 211-231
-
(2004)
J. Mol. Histol.
, vol.35
, pp. 211-231
-
-
Marhaba, R.1
Zoller, M.2
-
156
-
-
0030444393
-
CD44 isoform expression in the diffuse neuroendocrine system. II Benign and malignant tumors
-
Komminoth P., Seelentag W.K., Saremaslani P., Heitz P.U., and Roth J. CD44 isoform expression in the diffuse neuroendocrine system. II Benign and malignant tumors. Histochem. Cell Biol. 106 (1996) 551-562
-
(1996)
Histochem. Cell Biol.
, vol.106
, pp. 551-562
-
-
Komminoth, P.1
Seelentag, W.K.2
Saremaslani, P.3
Heitz, P.U.4
Roth, J.5
-
157
-
-
0033996006
-
Expression of CD44 variant isoforms and association to the benign form of endocrine pancreatic tumors
-
Imam H., Eriksson B., and Oberg K. Expression of CD44 variant isoforms and association to the benign form of endocrine pancreatic tumors. Ann. Oncol. 11 (2000) 295-300
-
(2000)
Ann. Oncol.
, vol.11
, pp. 295-300
-
-
Imam, H.1
Eriksson, B.2
Oberg, K.3
-
158
-
-
0035871299
-
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44
-
Morrison H., Sherman L.S., Legg J., Banine F., Isacke C., Haipek C.A., Gutmann D.H., Ponta H., and Herrlich P. The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44. Genes Dev. 15 (2001) 968-980
-
(2001)
Genes Dev.
, vol.15
, pp. 968-980
-
-
Morrison, H.1
Sherman, L.S.2
Legg, J.3
Banine, F.4
Isacke, C.5
Haipek, C.A.6
Gutmann, D.H.7
Ponta, H.8
Herrlich, P.9
-
159
-
-
0037059043
-
The role of chromosomal instability in tumor initiation
-
Nowak M.A., Komarova N.L., Sengupta A., Jallepalli P.V., Shih I.M., Vogelstein B., and Lengauer C. The role of chromosomal instability in tumor initiation. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 16226-16231
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 16226-16231
-
-
Nowak, M.A.1
Komarova, N.L.2
Sengupta, A.3
Jallepalli, P.V.4
Shih, I.M.5
Vogelstein, B.6
Lengauer, C.7
-
160
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B., and Kinzler K.W. Cancer genes and the pathways they control. Nat. Med. 10 (2004) 789-799
-
(2004)
Nat. Med.
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
162
-
-
0035217078
-
A novel insulinoma tumor suppressor gene locus on chromosome 22q with potential prognostic implications
-
Wild A., Langer P., Ramaswamy A., Chaloupka B., and Bartsch D.K. A novel insulinoma tumor suppressor gene locus on chromosome 22q with potential prognostic implications. J. Clin. Endocrinol. Metab. 86 (2001) 5782-5787
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 5782-5787
-
-
Wild, A.1
Langer, P.2
Ramaswamy, A.3
Chaloupka, B.4
Bartsch, D.K.5
-
163
-
-
0020694116
-
Glycoprotein-hormone alpha-chain production by pancreatic endocrine tumors: a specific marker for malignancy. Immunocytochemical analysis of tumors of 155 patients
-
Heitz P.U., Kasper M., Kloppel G., Polak J.M., and Vaitukaitis J.L. Glycoprotein-hormone alpha-chain production by pancreatic endocrine tumors: a specific marker for malignancy. Immunocytochemical analysis of tumors of 155 patients. Cancer 51 (1983) 277-282
-
(1983)
Cancer
, vol.51
, pp. 277-282
-
-
Heitz, P.U.1
Kasper, M.2
Kloppel, G.3
Polak, J.M.4
Vaitukaitis, J.L.5
-
165
-
-
0025612521
-
Aneuploidy in pancreatic insulinomas does not predict malignancy
-
Graeme-Cook F., Bell D.A., Flotte T.J., Preffer F., Pastel-Levy C., Nardi G., and Compton C. Aneuploidy in pancreatic insulinomas does not predict malignancy. Cancer 66 (1990) 2365-2368
-
(1990)
Cancer
, vol.66
, pp. 2365-2368
-
-
Graeme-Cook, F.1
Bell, D.A.2
Flotte, T.J.3
Preffer, F.4
Pastel-Levy, C.5
Nardi, G.6
Compton, C.7
-
166
-
-
0035161949
-
Immunohistochemical analysis of cyclooxygenase (COX)-2 expression in pancreatic endocrine tumors: association with tumor progression and proliferation
-
Ohike N., and Morohoshi T. Immunohistochemical analysis of cyclooxygenase (COX)-2 expression in pancreatic endocrine tumors: association with tumor progression and proliferation. Pathol. Int. 51 (2001) 770-777
-
(2001)
Pathol. Int.
, vol.51
, pp. 770-777
-
-
Ohike, N.1
Morohoshi, T.2
-
167
-
-
0035746857
-
Anomalous overexpression of p27(Kip1) in sporadic pancreatic endocrine tumors
-
Guo S.S., Wu X., Shimoide A.T., Wong J., and Sawicki M.P. Anomalous overexpression of p27(Kip1) in sporadic pancreatic endocrine tumors. J. Surg. Res. 96 (2001) 284-288
-
(2001)
J. Surg. Res.
, vol.96
, pp. 284-288
-
-
Guo, S.S.1
Wu, X.2
Shimoide, A.T.3
Wong, J.4
Sawicki, M.P.5
-
168
-
-
0242300585
-
Loss of p27 nuclear expression in a prognostically favorable subset of well-differentiated pancreatic endocrine neoplasms
-
Rahman A., Maitra A., Ashfaq R., Yeo C.J., Cameron J.L., and Hansel D.E. Loss of p27 nuclear expression in a prognostically favorable subset of well-differentiated pancreatic endocrine neoplasms. Am. J. Clin. Pathol. 120 (2003) 685-690
-
(2003)
Am. J. Clin. Pathol.
, vol.120
, pp. 685-690
-
-
Rahman, A.1
Maitra, A.2
Ashfaq, R.3
Yeo, C.J.4
Cameron, J.L.5
Hansel, D.E.6
-
169
-
-
7244231082
-
Prevalence of CD99 protein expression in pancreatic endocrine tumors (PETs)
-
Goto A., Niki T., Terado Y., Fukushima J., and Fukayama M. Prevalence of CD99 protein expression in pancreatic endocrine tumors (PETs). Histopathology 45 (2004) 384-392
-
(2004)
Histopathology
, vol.45
, pp. 384-392
-
-
Goto, A.1
Niki, T.2
Terado, Y.3
Fukushima, J.4
Fukayama, M.5
-
170
-
-
33751324523
-
The predictive value of CK19 and CD99 in pancreatic endocrine tumors
-
Ali A., Serra S., Asa S.L., and Chetty R. The predictive value of CK19 and CD99 in pancreatic endocrine tumors. Am. J. Surg. Pathol. 30 (2006) 1588-1594
-
(2006)
Am. J. Surg. Pathol.
, vol.30
, pp. 1588-1594
-
-
Ali, A.1
Serra, S.2
Asa, S.L.3
Chetty, R.4
-
171
-
-
0031441515
-
Reproducable and highly sensitive detection of the broad spectrum epithelial marker keratin 19 in routine cancer diagnosis
-
Kwaspen F.H.L., Smedts F.M.M., Broos A., Bulten H., Debie W.M.H., and Ramaekers F.C.S. Reproducable and highly sensitive detection of the broad spectrum epithelial marker keratin 19 in routine cancer diagnosis. Histopathology 31 (1997) 503-516
-
(1997)
Histopathology
, vol.31
, pp. 503-516
-
-
Kwaspen, F.H.L.1
Smedts, F.M.M.2
Broos, A.3
Bulten, H.4
Debie, W.M.H.5
Ramaekers, F.C.S.6
-
172
-
-
0031914251
-
Cytokeratins and cell differentiation in the pancreas
-
Bouwens L. Cytokeratins and cell differentiation in the pancreas. J. Pathol. 184 (1998) 234-239
-
(1998)
J. Pathol.
, vol.184
, pp. 234-239
-
-
Bouwens, L.1
-
173
-
-
4344624321
-
Cytokeratin 19 is a powerful predictor of survival in pancreatic endocrine tumors
-
Deshpande V., Fernandez-del Castillo C., Muzikansky A., Deshpande A., Zukerberg L., Warshaw A.L., and Lauwers G.Y. Cytokeratin 19 is a powerful predictor of survival in pancreatic endocrine tumors. Am. J. Surg. Pathol. 28 (2004) 1145-1153
-
(2004)
Am. J. Surg. Pathol.
, vol.28
, pp. 1145-1153
-
-
Deshpande, V.1
Fernandez-del Castillo, C.2
Muzikansky, A.3
Deshpande, A.4
Zukerberg, L.5
Warshaw, A.L.6
Lauwers, G.Y.7
-
174
-
-
33947614079
-
Prognostic and biological significance of cytokeratin 19 in pancreatic endocrine tumors
-
La Rosa S., Rigoli E., Uccella S., Novario R., and Capella C. Prognostic and biological significance of cytokeratin 19 in pancreatic endocrine tumors. Histopathology 50 (2007) 597-606
-
(2007)
Histopathology
, vol.50
, pp. 597-606
-
-
La Rosa, S.1
Rigoli, E.2
Uccella, S.3
Novario, R.4
Capella, C.5
-
175
-
-
33751539800
-
Cytokeratin 19 expression in pancreatic endocrine tumors
-
Albarello L., Capitanio V., Zerbi A., Di Carlo V., and Doglioni C. Cytokeratin 19 expression in pancreatic endocrine tumors. J. Pancreas 6 (2004) 514
-
(2004)
J. Pancreas
, vol.6
, pp. 514
-
-
Albarello, L.1
Capitanio, V.2
Zerbi, A.3
Di Carlo, V.4
Doglioni, C.5
-
176
-
-
1842615074
-
Mouse models of human familial cancer syndromes
-
Ward J.M., and Devor-Henneman D.E. Mouse models of human familial cancer syndromes. Toxicol. Pathol. 32 (2004) 90-98
-
(2004)
Toxicol. Pathol.
, vol.32
, pp. 90-98
-
-
Ward, J.M.1
Devor-Henneman, D.E.2
-
177
-
-
0021888904
-
Heritable formation of pancreatic beta-cell tumors in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes
-
Hanahan D. Heritable formation of pancreatic beta-cell tumors in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature 315 (1985) 115-122
-
(1985)
Nature
, vol.315
, pp. 115-122
-
-
Hanahan, D.1
-
178
-
-
0028641171
-
The human carcinoid cell line, BON. A model system for the study of carcinoid tumors
-
Evers B.M., Ishizuha J., Townsend Jr. C.M., and Thompson J.C. The human carcinoid cell line, BON. A model system for the study of carcinoid tumors. Ann. N. Y. Acad. Sci. 733 (1994) 393-406
-
(1994)
Ann. N. Y. Acad. Sci.
, vol.733
, pp. 393-406
-
-
Evers, B.M.1
Ishizuha, J.2
Townsend Jr., C.M.3
Thompson, J.C.4
-
179
-
-
0025339152
-
A somatostatin-secreting cell line established from a human pancreatic islet cell carcinoma (somatostatinoma): release experiment and immunohistochemical study
-
Iguchi H., Hayashi I., and Kono A. A somatostatin-secreting cell line established from a human pancreatic islet cell carcinoma (somatostatinoma): release experiment and immunohistochemical study. Cancer Res. 50 (1990) 3691-3693
-
(1990)
Cancer Res.
, vol.50
, pp. 3691-3693
-
-
Iguchi, H.1
Hayashi, I.2
Kono, A.3
-
180
-
-
0032927064
-
Beta-cell gene expression and functional characterisation of the human insulinoma cell line CM
-
Baroni M.G., Cavallo M.G., Mark M., Monetini L., Stoehrer B., and Pozzilli P. Beta-cell gene expression and functional characterisation of the human insulinoma cell line CM. J. Endocrinol. 161 (1999) 59-68
-
(1999)
J. Endocrinol.
, vol.161
, pp. 59-68
-
-
Baroni, M.G.1
Cavallo, M.G.2
Mark, M.3
Monetini, L.4
Stoehrer, B.5
Pozzilli, P.6
-
181
-
-
33747598234
-
Long-term in vitro growth of human insulin-secreting insulinoma cells
-
Gartner W., Koc F., Nabokikh A., Daneva T., Niederle B., Luger A., and Wagner L. Long-term in vitro growth of human insulin-secreting insulinoma cells. Neuroendocrinology 83 (2006) 123-130
-
(2006)
Neuroendocrinology
, vol.83
, pp. 123-130
-
-
Gartner, W.1
Koc, F.2
Nabokikh, A.3
Daneva, T.4
Niederle, B.5
Luger, A.6
Wagner, L.7
-
182
-
-
34250197654
-
New drug development in digestive neuroendocrine tumors
-
(Epub ahead of print)
-
Duran I., Salazar R., Casanovas O., Arrazubi V., Vilar E., Siu L.L., Yao J., and Tabernero J. New drug development in digestive neuroendocrine tumors. Ann. Oncol. (2007) (Epub ahead of print)
-
(2007)
Ann. Oncol.
-
-
Duran, I.1
Salazar, R.2
Casanovas, O.3
Arrazubi, V.4
Vilar, E.5
Siu, L.L.6
Yao, J.7
Tabernero, J.8
|