Telomerase activity in pancreatic endocrine tumors

American Journal of Gastroenterology

Volumn 97, Issue 4, 2002, Pages 1022-1030

  Tang, Shou Jiang ^a   Dumot, John A ^a   Wang, Liming ^a   Memmesheimer, Christian ^a   Conwell, Darwin L ^a   Zuccaro, Gregory ^a   Goormastic, Marlene ^a   Ormsby, Adrian H ^a   Cowell, John ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE;

ACINAR CELL CARCINOMA; ADULT; ARTICLE; CANCER SURVIVAL; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENDOCRINE TUMOR; ENZYME ACTIVITY; FOLLOW UP; FROZEN SECTION; GLUCAGONOMA; HUMAN; HUMAN TISSUE; MULTIPLE ENDOCRINE NEOPLASIA; PANCREAS CELL; PANCREAS TUMOR; PRIORITY JOURNAL; PROGNOSIS; SURVIVAL TIME; TELOMERE; TUMOR GROWTH; VIPOMA; VON HIPPEL LINDAU DISEASE;

ADENOMA, ISLET CELL; ADULT; AGED; CARCINOMA, ACINAR CELL; FEMALE; HUMANS; ISLETS OF LANGERHANS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; SURVIVAL RATE; TELOMERASE;

EID: 0036120241     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9270(02)03979-5     Document Type: Article

References (25)

1. Pancreatic endocrine tumors: Recent advances
2. Growth of newly diagnosed, untreated metastatic gastrinomas and predictors of growth patterns
3. Determinants of metastatic rate and survival in patients in patients with Zollinger-Ellison syndrome: A prospective long-term study
4. Endocrine tumors of the pancreas: Clinical picture, diagnosis, and therapy
5. Gastrinoma
6. Extension of life span by introduction of telomerase into normal human cells
7. Expression of TERT in early premalignant lesions and a subset of cells in normal tissues
8. Reconstitution of telomerase activity in normal human cells leads to elongation of telomerase and extended replicative life span
9. Telomerase: A promising marker of biological immortality of germ, stem and cancer cells; a review
10. Specific association of human telomerase activity with immortal cells and cancer
11. A survey of telomerase activity in human cancer
12. Telomerase acitivity in human solid tumors
13. Telomerase expression in intracranial tumors: Prognostic potential for malignant gliomas and meningiomas
14. The RNA component of telomerase as a marker of biologic potential and clinical outcome in chilhood neuroblastic tumors
15. In situ hybridization for the detection of telomerase RNA in the progression from Barrett's esophagus to esophageal adenocarcinoma
16. In situ mRNA hybridization technique for analysis of human telomerase RNA in gastric precancerous and cancerous lesions
17. Human telomerase RNA expression and MIB-1(Ki-67) proliferation index distinguish hemangioblastomas from metastatic renal cell carcinomas
18. Telomerase activity distinguishes between neuroblastomas with good and poor prognosis
19. Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP)
20. Telomerase activity is detected in pancreatic cancer but not in benign tumors
21. Rapid detection of MYCN gene amplification and telomerase expression in neuroblastoma
22. Telomerase activity is an useful marker to distinguish malignant pancreatic cystic tumors from benign neoplasms and pseudocysts
23. Telomerase activity detected in pancreatic juice 19 months before a tumor is detected in a patient with pancreatic cancer
24. Diagnosis pancreatic cancer by detecting telomerase activity in pancreatic juice: Comparison with K-ras mutations
25. Prospective study of the clinical course, prognostic factors, causes of death, and survival in patients with longstanding Zollinger-Ellison syndrome