mRNA expression patterns of insulin-like growth factor system components in human neuroendocrine tumours

European Journal of Clinical Investigation

Volumn 30, Issue 8, 2000, Pages 729-739

  Wulbrand, U ^a,b   Remmert, G ^a   Zofel P ^a   Wied, M ^a   Arnold, R ^a   Fehmann, H C ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Human neuroendocrine tumours; Insulin like growth factor system; mRNA expression pattern; Reverse transcriptase polymerase chain reaction

Indexed keywords

MESSENGER RNA; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN BINDING PROTEIN 4; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN BINDING PROTEIN 6; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ARTICLE; CARCINOGENESIS; CARCINOID SYNDROME; CLINICAL ARTICLE; GASTRINOMA; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; INSULINOMA; NEUROENDOCRINE TUMOR; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

GASTRINOMA; GENE EXPRESSION PROFILING; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; INSULINOMA; NEUROENDOCRINE TUMORS; PANCREATIC NEOPLASMS; RECEPTOR, IGF TYPE 1; RECEPTOR, IGF TYPE 2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STATISTICS;

EID: 0033852721     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.2000.00700.x     Document Type: Article

References (47)

1. 1 Pusztai L, Lewis CE, Yap E editors. Cell Proliferation in Cancer: Regulatory Mechanisms of Neoplastic Cell Growth Oxford: Oxford University Press; 1996.
2. 2 Culig Z., Hobisch A., Cronauer MV, Radmayr C., Hittraair A., Zhang J et al. Regulation of prostatic growth and function by peptide growth factors. The Prostate 1996;28:392-405.
3. 3 Bergmann U, Funatomi H, Yokoyama M, Beger HG, Korc M. Insulin-like growth factor I overexpression in human pancreatic cancer: evidence for autocrine and paracrine roles. Cancer Res 1995;55:2007-11.
4. 4 Papa V, Gliozzo B, Clark GM, McGuire WL, Moore D, Fujita-Yamaguchi Y et al. Insulin-like growth factor receptors are overexpressed and predict a low risk in human breast cancer. Cancer Res 1993;53:3736-40.
5. 5 Tricoli JV, Rall LB, Karakousis CP, Herrea L, Petrelli NJ, Bell GI et al. Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas. Cancer Res 1986;46:6169-73.
6. 6 Chen S-C, Chou C-K, Wong F-H, Chang C, Hu C-P. Overexpression of epidermal growth factor and insulin-like growth factor-I receptors and autocrine stimulation in human esophageal carcinoma cells. Cancer Res 1991;51:1898-903.
7. 7 Korc M. Role of growth factors in pancreatic cancer. Surg Oncol Clin N Am 1998;7(1):25-41.
8. 8 Baserga R, Hongo A, Rubini M, Prisco M, Valentinis B. The IGF-I receptor in cell growth. Transformation Apoptosis Biochim Biophys Acta 1997;1332:F105-F126.
9. 9 Rechler MM, Clemmons DR. Regulatory actions of insulin-like growth factor-binding proteins. TEM 1998;9(5):176-83.
10. 10 Kim H-S, Nagalla SR, Oh Y, Wilson E, Roberts JRCT, Rosenfeld RG. Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily Proceedings Natl Acad Sci USA 1997;94:12981-6.
11. 11 Daughaday WH, Rotwein P. Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum and tissue concentrations Endocr Rev 1989;10:68-91.
12. 12 Nakanishi Y, Mulshine JL, Kasprzyk PG, Natale RB, Maneckjee R, Avis I et al. Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines. J Clin Invest 1988;82:354-9.
13. 13 Osborne CK, Clemonds DR, Arteaga CI. Regulation of breast cancer growth by insulin-like growth factors. J Steroid Biochem Molec Biol 1990;37:805-9.
14. 14 Manni A., Wel L., Badger B., Zaenglein A., Leighton J., Shimasaki S et al. Expression of messenger RNA for insulin-like growth factors and insulin-like growth factor binding proteins by experimental breast cancer and normal breast tissue in vivo Endocrinology 1992;130:1744-6.
15. 15 Hoeflich A, Yang Y, Rascher W, Blum WF, Hubert S, Koepf G et al. Coordinate expression of insulin-like growth factor II (IGF-II) and IGF-II/mannose-6-phosphate receptor mRNA and stable expression of IGF-I receptor mRNA during differentiation of human colon carcinoma cells (Caco.2). Europ J Endocrinol 1996;135:49-59.
16. 16 Suzuki T, Iwafuchi M, Yanaihara C, Hatanaka H, Tao Z, Yanaihara N et al. IGF-II-like immunoreactivity in human tissues, neuroendocrine tumors, and PC12 cells. Diabet Res Clin Practice 1989;7:S21-S27.
17. 17 Macaulay VM. Insulin-like growth factors and cancer. Br J Cancer 1992;65(3):311-20.
18. 18 Kornfeld S. Structure and function of the mannose-6-phosphate/insulin-like growth factor II receptor. Annu Rev Biochem 1992;61:307-30.
19. 19 Hankins GR, De Souza AT, Bentley RC, Patel MR, Marks JR, Iglehart JD et al. M6P/IGF2 receptor: a candidate breast tumor suppressor gene. Oncogene 1996;12:2003-9.
20. 20 De Souza AT, Hankins GR, Washington MK, Orton TC, Jirtle RL. M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity. Nat Genet 1995;11:447-9.
21. 21 Souza R, Appel R, Yin J, Wang S, Smolinski K, Abraham J et al. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours. Nat Genet 1996;14:255-7.
22. 22 Oh Y. IGFBPs and neoplastic models. Endocrine 1997;7(1):111-13.
23. 23 Ilvesmaki V, Liu J, Heikkila P, Kahri AI, Voutilainen R. Expression of insulin-like growth factor binding protein 1-6 genes in adrenocortical tumors and pheochromocytomas. Horm Metab Res 1998;30(10):619-23.
24. 24 Wulbrand U, Wied M, Zöfel P, Göke B, Arnold R, Fehmann H-C. Growth factor receptor expression in human gastroenteropancreatic neuroendocrine tumours. Europ J Clin Invest 1998;28:1038-49.
25. 25 Capella C, Heitz PU, Höfler H, Solcia E, Kloppel G. Revised classification of neuroendocrine tumors of the lung, pancreas and gut. Digestion 1994;55(Suppl. 3):11-23.
26. 26 Fisher RA. Statistical Methods of Research Workers. 17th edn London: Oliver and Boyd;1972.
27. 27 Ankrapp DP, Bevan DR. Insulin-like growth factor-I and human lung fibroblast-derived insulin-like growth factor-I stimulate the proliferation of human lung carcinoma cells in vitro. Cancer Res 1993;53:3399-404.
28. 28 Buscail L, Esteve JP, Saint-Laurent N, Bertrand V, Reisine T, O'Carroll AM et al. Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR 2 and SSTR 5 through different mechanisms. Proc Natl Acad Sci USA 1995;92:1580-4.
29. 29 Raile K, Höflich A, Kessler Y, Yang Y, Pfuender M, Blum WF et al. Human osteosarcoma (U-2 OS) cells express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptors and synthesize IGF-II. autocrine growth stimulation by IGF-II via the IGF-I receptor. J Cellular Physiol 1994;159:531-41.
30. 30 Zarrilli R., Pignata S., Romano M., Gravina A., Casola S., Bruni CB et al. Expression of insulin-like growth factor (IGF) -II and IGF-I receptor during proliferation and differentiation of CaCo-2 human colon carcinoma cells. Cell Growth Differentiation 1994;5:1085-91.
31. 31 Sciacca L, Costantino A, Pandini G, Mineo R, Frasca F, Scalia P et al. Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism. Oncogene 1999;18(15):2471-9.
32. 32 Frasca F, Pandini G, Scalia P, Sciacca L, Mineo R, Costantino A et al. Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells. Mol Cell Biol 1999;19(5):3278-88.
33. 33 Oates AJ, Schumaker LM, Jenkins SB, Pearce AA, DaCosta SA, Arun B et al. The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene. Breast Cancer Res Treat 1998;47(3):269-81.
34. 34 Yashiro T, Tsushima T, Murakami H, Obara T, Fujimoto Y, Shizume K et al. Insulin-like growth factor-II (IGF-II) /Mannose-6-phosphate receptors are increased in primary human thyroid neoplasms. Eur J Cancer 1991;27(6):699-703.
35. 35 Jones JI, Clemons DR. Insulin-like growth factors and their binding proteins, biological actions. Endocr Rev 1995;16:3-34.
36. 36 Kelley KM, Oh Y, Gargosky SE, Gucev Z, Matsumoto T, Hwa V et al. Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics. Im J Biochem Cell Biol 1996;28(6):619-37.
37. 37 Reeve JG, Morgan J, Schwander J, Blechen NM. Role for membrane and secreted insulin-like growth factor-binding protein-2 in the regulation of insulin-like growth factor action in lung tumors. Cancer Res 1993;53(19):4680-5.
38. 38 Kanety H, Kattan M, Goldberg I, Kopolovic J, Ravia J, Menczer J et al. Increased insulin-like growth factor binding protein-2 (IGFBP-2) gene expression and protein production lead to high IGFBP-2 content in malignant ovarian cyst fluid. Br J Cancer 1996;73(9):1069-73.
39. 39 Collett-Solberg PF, Cohen P. The role of the insulin-like growth factor binding proteins and the IGFBP proteases in modulating IGF action. Endocrinol Metab Clin North Am 1996;25(3):591-614.
40. 40 Leal SM, Liu Q, Huang SS, Huang JS. The type V transforming growth factor β receptor is the putative insulin-like growth factor-binding protein 3 receptor. J Biol Chem, 1997;272(33):20572-6.
41. 41 Fowlkes J, Freemark M. Evidence for a novel insulin-like growth factor (IGF) -dependent protease regulating IGF-binding protein-4 in dermal fibroblasts. Endocrinology 1992;131:2071-6.
42. 42 Clemmons DR. Modification of IGF action by insulin-like growth factor binding protein-5. In: Baxter RC, Gluckmann PD, Rosenfeld RG, editors. The Insulin-like Growth Factors and Their Regulatory Proteins. Amsterdam: Elsevier; 1994.p. 183-91.
43. 43 Menouny M, Binoux M, Babajko S. IGFBP-2 expression in a human cell line is associated with increased IGFBP-3 proteolysis, decreased IGFBP-1 expression and increased tumorigenicity. Int J Cancer 1998;77(6):874-9.
44. 44 Figueroa JA, Jackson JG, McGuire WL, Krywicki RF, Yee D. Expression of insulin-like growth factor binding proteins in human breast cancer correlates with estrogen receptor status. J Cell Biochem 1993;52(2): 196-205.
45. 45 Wegmann BR, Schoneberger HJ, Kiefer PE, Jaques G, Brandscheid D, Havemann K. Molecular cloning of IGFBP-5 from SCLC cell lines and expression of IGFBP-4, IGFBP-5 and IGFBP-6 in lung cancer cell lines and primary tumours. Eur J Cancer 1993;29A(11):1578-84.
46. 46 Hofmann J, Wegmann B, Hackenberg R, Kunzmann R, Schulz KD, Havemann K. Production of insulin-like growth factor binding proteins by human ovarian carcinoma cells. J Cancer Res Clin Oncol 1994;120(3): 137-42.
47. 47 Tennant MK, Thrasher JB, Twomey PA, Birnbaum RS, Plymate SR. Insulin-like growth factor-binding proteins (IGFBP) -4-5, and -6 in the benign and malignant human prostate: IGFBP-5 messenger ribonucleic acid localization differs from IGFBP-5 protein localization. J Clin Endocrinol Metab 1996;81(10):3783-92.