Mitocans as anti-cancer agents targeting mitochondria: Lessons from studies with vitamin e analogues, inhibitors of complex II

Journal of Bioenergetics and Biomembranes

Volumn 39, Issue 1, 2007, Pages 65-72

  Neuzil, Jiri ^a,b   Dyason, Jeffrey C ^a   Freeman, Ruth ^a   Dong, Lan Feng ^a   Prochazka, Lubomir ^c   Wang, Xiu Fang ^a   Scheffler, Immo ^d   Ralph, Stephen J ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^c VETERINARY RESEARCH INSTITUTE   (Czech Republic)

^d SECTION OF MOLECULAR BIOLOGY   (United States)

Author keywords

Apoptosis; Cancer; Coenzyme Q; Complex II; Mitocans; Mitochondria; Superoxide; Vitamin E analogues

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; MITOCHONDRIAL DNA; SUCCINATE DEHYDROGENASE (UBIQUINONE);

ANTINEOPLASTIC ACTIVITY; CELL MEMBRANE PERMEABILITY; CONFORMATIONAL TRANSITION; DIMERIZATION; DRUG BINDING; DRUG TARGETING; GENE OVEREXPRESSION; HEMATOLOGIC MALIGNANCY; HUMAN; MITOCHONDRIAL DNA DEPLETION; PROMYELOCYTIC LEUKEMIA; PROTEIN CONFORMATION; SHORT SURVEY; TUMOR CELL DESTRUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; ELECTRON TRANSPORT COMPLEX II; HUMANS; MITOCHONDRIA; MODELS, MOLECULAR; NEOPLASMS; REACTIVE OXYGEN SPECIES; SUPEROXIDES; VITAMIN E;

TOSCANA VIRUS;

EID: 34249934598     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-006-9060-z     Document Type: Short Survey

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