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Volumn 18, Issue 10, 1998, Pages 6083-6089

Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DELETION MUTANT; DIMERIZATION; GENE STRUCTURE; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; RAT; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

EID: 0031660082     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.10.6083     Document Type: Article
Times cited : (194)

References (29)
  • 5
    • 0029670590 scopus 로고    scopus 로고
    • New members of the Bcl-2 family and their protein partners
    • Farrow, S. N., and R. Brown. 1996. New members of the Bcl-2 family and their protein partners. Curr. Opin. Genet. Dev. 6:45-49.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 45-49
    • Farrow, S.N.1    Brown, R.2
  • 6
    • 0032528118 scopus 로고    scopus 로고
    • Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis
    • Gross, A., J. Jockei, M. Wei, and S. J. Korsmeyer. 1998. Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J. 17:3878-3885.
    • (1998) EMBO J. , vol.17 , pp. 3878-3885
    • Gross, A.1    Jockei, J.2    Wei, M.3    Korsmeyer, S.J.4
  • 7
    • 0029868112 scopus 로고    scopus 로고
    • The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein
    • Han, J., P. Sabbatini, D. Perez, L. Rao, D. Modha, and E. White. 1996. The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein. Genes Dev. 10:461-477.
    • (1996) Genes Dev. , vol.10 , pp. 461-477
    • Han, J.1    Sabbatini, P.2    Perez, D.3    Rao, L.4    Modha, D.5    White, E.6
  • 9
    • 0029928885 scopus 로고    scopus 로고
    • A peptide sequence from Bax that converts Bcl-2 into an activator of apoptosis
    • Hunter, J. J., and T. G. Parslow. 1996. A peptide sequence from Bax that converts Bcl-2 into an activator of apoptosis. J. Biol. Chem. 271:8521-8524.
    • (1996) J. Biol. Chem. , vol.271 , pp. 8521-8524
    • Hunter, J.J.1    Parslow, T.G.2
  • 10
    • 0030861571 scopus 로고    scopus 로고
    • Bcl-2 and Bax function independently to regulate cell death
    • Knudson, C. M., and S. J. Korsmeyer. 1997. Bcl-2 and Bax function independently to regulate cell death. Nat. Genet. 16:358-363.
    • (1997) Nat. Genet. , vol.16 , pp. 358-363
    • Knudson, C.M.1    Korsmeyer, S.J.2
  • 11
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer, G. 1997. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med. 3:614-620.
    • (1997) Nat. Med. , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 14
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai, Z. N., C. L. Milliman, and S. J. Korsmeyer. 1993. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 21
    • 0029752013 scopus 로고    scopus 로고
    • Bax homodimerization is not required for Bax to accelerate chemotherapy-induced cell death
    • Simonian, P. L., D. A. M. Grillot, D. W. Andrews, B. Leber, and G. Nuñez. 1996. Bax homodimerization is not required for Bax to accelerate chemotherapy-induced cell death. J. Biol. Chem. 271:32073-32077.
    • (1996) J. Biol. Chem. , vol.271 , pp. 32073-32077
    • Simonian, P.L.1    Grillot, D.A.M.2    Andrews, D.W.3    Leber, B.4    Nuñez, G.5
  • 23
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller, H. 1995. Mechanisms and genes of cellular suicide. Science 267: 1445-1449.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 26
    • 0029906828 scopus 로고    scopus 로고
    • Bax-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases
    • Xiang, J., D. T. Chao, and S. J. Korsmeyer. 1996. Bax-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases. Proc. Natl. Acad. Sci. USA 93:14559-14563.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14559-14563
    • Xiang, J.1    Chao, D.T.2    Korsmeyer, S.J.3
  • 27
    • 0028206341 scopus 로고
    • BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
    • Yin, X. M., Z. N. Oltvai, and S. J. Korsmeyer. 1994. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 369:321-323.
    • (1994) Nature , vol.369 , pp. 321-323
    • Yin, X.M.1    Oltvai, Z.N.2    Korsmeyer, S.J.3
  • 28
    • 0031436251 scopus 로고    scopus 로고
    • Heterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells
    • Zha, H., and J. C. Reed. 1997. Heterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells. J. Biol. Chem. 272:31482-31488.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31482-31488
    • Zha, H.1    Reed, J.C.2
  • 29
    • 0029917541 scopus 로고    scopus 로고
    • Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2
    • Zha, H., C. Aime-Sempe, T. Sato, and J. C. Reed. 1996. Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2. J. Biol. Chem. 271:7440-7444.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7440-7444
    • Zha, H.1    Aime-Sempe, C.2    Sato, T.3    Reed, J.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.