-
1
-
-
33646160623
-
Inflammation, a key event in cancer development
-
Lu, H.; Ouyang, W.; Huang, C. Inflammation, a key event in cancer development. Mol. Cancer Res. 2006, 4, 1-13.
-
(2006)
Mol. Cancer Res
, vol.4
, pp. 1-13
-
-
Lu, H.1
Ouyang, W.2
Huang, C.3
-
2
-
-
0031034051
-
Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells
-
Rincon, M.; Flavell, R. A. Transcription mediated by NFAT is highly inducible in effector CD4+ T helper 2 (Th2) cells but not in Th1 cells. Mol. Cell. Biol. 1997, 17 , 1522-1534.
-
(1997)
Mol. Cell. Biol
, vol.17
, pp. 1522-1534
-
-
Rincon, M.1
Flavell, R.A.2
-
3
-
-
16844382568
-
NFAT transcription factors: From cell cycle to tumor development
-
Viola, J. P. B.; Carvalho, L. D. S.; Fonseca, B. P. F.; Teixeira, L. K. NFAT transcription factors: from cell cycle to tumor development. Braz. J. Med. Biol. Res. 2005, 38 , 335-344.
-
(2005)
Braz. J. Med. Biol. Res
, vol.38
, pp. 335-344
-
-
Viola, J.P.B.1
Carvalho, L.D.S.2
Fonseca, B.P.F.3
Teixeira, L.K.4
-
4
-
-
0033594887
-
NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun
-
López-Rodríguez, C.; Aramburu, J.; Rakeman, A. S.; Rao, A. NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun. Proc. Natl. Acad. Sci. USA 1999, 96 , 7214-7219.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7214-7219
-
-
López-Rodríguez, C.1
Aramburu, J.2
Rakeman, A.S.3
Rao, A.4
-
5
-
-
20644466433
-
NFAT proteins: Key regulators of T-cell development and function
-
Macian, F. NFAT proteins: key regulators of T-cell development and function. Nat. Rev. Immunol. 2005, 5, 472-484.
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 472-484
-
-
Macian, F.1
-
6
-
-
0141483523
-
Transcriptional regulation by calcium, calcineurin, and NFAT
-
Hogan, P. G.; Chen, L.; Nardone, J.; Rao, A. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev. 2003, 17 , 2205-2232.
-
(2003)
Genes Dev
, vol.17
, pp. 2205-2232
-
-
Hogan, P.G.1
Chen, L.2
Nardone, J.3
Rao, A.4
-
7
-
-
0030973579
-
Transcription factors of the NFAT family: Regulation and function
-
Rao, A.; Luo, C.; Hogan, P. G. Transcription factors of the NFAT family: regulation and function. Annu. Rev. Immunol. 1997, 15 , 707-747.
-
(1997)
Annu. Rev. Immunol
, vol.15
, pp. 707-747
-
-
Rao, A.1
Luo, C.2
Hogan, P.G.3
-
8
-
-
4444260305
-
Structural delineation of the calcineurin-NFAT interaction and its parallels to PP1 targeting interactions
-
Li, H.; Rao, A.; Hogan, P. G. Structural delineation of the calcineurin-NFAT interaction and its parallels to PP1 targeting interactions. J. Mol. Biol. 2004, 342, 1659-1674.
-
(2004)
J. Mol. Biol
, vol.342
, pp. 1659-1674
-
-
Li, H.1
Rao, A.2
Hogan, P.G.3
-
9
-
-
15444379702
-
The linker region joining the catalytic and the regulatory domains of CnA is essential for binding to NFAT
-
Rodríguez, A.; Martínez-Martínez, S.; López-Maderuelo, M. D.; Ortega-Pérez, I.; Redondo, J. M. The linker region joining the catalytic and the regulatory domains of CnA is essential for binding to NFAT. J. Biol. Chem. 2005, 280, 9980-9984.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 9980-9984
-
-
Rodríguez, A.1
Martínez-Martínez, S.2
López-Maderuelo, M.D.3
Ortega-Pérez, I.4
Redondo, J.M.5
-
10
-
-
0033634846
-
Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity
-
Okamura, H.; Aramburu, J.; García-Rodríguez, C.; Viola, J. P.; Raghavan, A.; Tahiliani, M.; Zhang, X.; Qin, J.; Hogan, P. G.; Rao, A. Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity. Mol. Cell 2000, 6, 539-550.
-
(2000)
Mol. Cell
, vol.6
, pp. 539-550
-
-
Okamura, H.1
Aramburu, J.2
García-Rodríguez, C.3
Viola, J.P.4
Raghavan, A.5
Tahiliani, M.6
Zhang, X.7
Qin, J.8
Hogan, P.G.9
Rao, A.10
-
11
-
-
33646564423
-
Blockade of NFAT activation by the second calcineurin binding site
-
Martínez-Martínez, S.; Rodríguez, A.; López-Maderuelo, M. D.; Ortega-Pérez, I.; Vázquez, J.; Redondo, J. M. Blockade of NFAT activation by the second calcineurin binding site. J. Biol. Chem. 2006, 281, 6227-6235.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 6227-6235
-
-
Martínez-Martínez, S.1
Rodríguez, A.2
López-Maderuelo, M.D.3
Ortega-Pérez, I.4
Vázquez, J.5
Redondo, J.M.6
-
12
-
-
3142544806
-
Dual role of sumoylation in the nuclear localization and transcriptional activation of NFAT1
-
Terui, Y.; Saad, N.; Jia, S.; McKeon, F.; Yuan, J. Dual role of sumoylation in the nuclear localization and transcriptional activation of NFAT1. J. Biol. Chem. 2004, 279, 28257-28265.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 28257-28265
-
-
Terui, Y.1
Saad, N.2
Jia, S.3
McKeon, F.4
Yuan, J.5
-
13
-
-
0034603165
-
Identification of amino acid residues and protein kinases involved in the regulation of NFATc subcellular localization
-
Porter, C. M.; Havens, M. A.; Clipstone, N. A. Identification of amino acid residues and protein kinases involved in the regulation of NFATc subcellular localization. J. Biol. Chem. 2000, 275, 3543-3551.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 3543-3551
-
-
Porter, C.M.1
Havens, M.A.2
Clipstone, N.A.3
-
14
-
-
0035793570
-
Glycogen synthase kinase-3 inhibits the DNA binding activity of NFATc
-
Neal, J. W.; Clipstone, N. A. Glycogen synthase kinase-3 inhibits the DNA binding activity of NFATc. J. Biol. Chem. 2001, 276, 3666-3673.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 3666-3673
-
-
Neal, J.W.1
Clipstone, N.A.2
-
15
-
-
0029851762
-
Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression
-
Timmerman, L. A.; Clipstone, N. A.; Ho, S. N.; Northrop, J. P.; Crabtree, G. R. Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression. Nature 1996, 383, 837-840.
-
(1996)
Nature
, vol.383
, pp. 837-840
-
-
Timmerman, L.A.1
Clipstone, N.A.2
Ho, S.N.3
Northrop, J.P.4
Crabtree, G.R.5
-
16
-
-
0040141604
-
A role for the p38 MAP kinase pathway in the nuclear shuttling of NFATp
-
Gómez del Arco, P.; Martínez-Martínez, S.; Maldonado, J. L.; Ortega-Pérez, I.; Redondo, J. M. A role for the p38 MAP kinase pathway in the nuclear shuttling of NFATp. J. Biol. Chem. 2000, 275, 13872-13878.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 13872-13878
-
-
Gómez del Arco, P.1
Martínez-Martínez, S.2
Maldonado, J.L.3
Ortega-Pérez, I.4
Redondo, J.M.5
-
17
-
-
0036094148
-
Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases
-
Yang, T. T.; Xiong, Q.; Enslen, H.; Davis, R. J.; Chow, C. W. Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases. Mol. Cell. Biol. 2002, 22 , 3892-3904.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 3892-3904
-
-
Yang, T.T.1
Xiong, Q.2
Enslen, H.3
Davis, R.J.4
Chow, C.W.5
-
18
-
-
0030890234
-
Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3
-
Beals, C. R.; Sheridan, C. M.; Turck, C. W.; Gardner, P.; Crabtree, G. R. Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3. Science 1997, 275, 1930-1934.
-
(1997)
Science
, vol.275
, pp. 1930-1934
-
-
Beals, C.R.1
Sheridan, C.M.2
Turck, C.W.3
Gardner, P.4
Crabtree, G.R.5
-
19
-
-
33646559053
-
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
-
Gwack, Y.; Sharma, S.; Nardone, J.; Tanasa, B.; Iuga, A.; Srikanth, S.; Okamura, H.; Bolton, D.; Feske, S.; Hogan, P. G.; Rao, A. A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT. Nature, 2006, 441(7093), 646-650.
-
(2006)
Nature
, vol.441
, Issue.7093
, pp. 646-650
-
-
Gwack, Y.1
Sharma, S.2
Nardone, J.3
Tanasa, B.4
Iuga, A.5
Srikanth, S.6
Okamura, H.7
Bolton, D.8
Feske, S.9
Hogan, P.G.10
Rao, A.11
-
20
-
-
0035844058
-
Binding and regulation of the transcription factor NFAT by the peptidyl prolyl cistrans isomerase Pin1
-
Liu, W.; Youn, H. D.; Zhou, X. Z.; Lu, K. P.; Liu, J. O. Binding and regulation of the transcription factor NFAT by the peptidyl prolyl cistrans isomerase Pin1. FEBS Lett. 2001, 496, 105-108.
-
(2001)
FEBS Lett
, vol.496
, pp. 105-108
-
-
Liu, W.1
Youn, H.D.2
Zhou, X.Z.3
Lu, K.P.4
Liu, J.O.5
-
21
-
-
24644481406
-
A strategy for probing the function of noncoding RNAs finds a repressor of NFAT
-
Willingham, A. T.; Orth, A. P.; Batalov, S.; Peters, E. C.; Wen, B. G.; Aza-Blanc, P.; Hogenesch, J. B.; Schultz, P. G. A strategy for probing the function of noncoding RNAs finds a repressor of NFAT. Science 2005, 309, 1570-1573.
-
(2005)
Science
, vol.309
, pp. 1570-1573
-
-
Willingham, A.T.1
Orth, A.P.2
Batalov, S.3
Peters, E.C.4
Wen, B.G.5
Aza-Blanc, P.6
Hogenesch, J.B.7
Schultz, P.G.8
-
22
-
-
33744960492
-
Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3
-
Wu, W.; Misra, R. S.; Russell, J. Q.; Flavell, R. A.; Rincón, M.; Budd, R. C. Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3. J. Biol. Chem 2006, 281(16), 10682-10690.
-
(2006)
J. Biol. Chem
, vol.281
, Issue.16
, pp. 10682-10690
-
-
Wu, W.1
Misra, R.S.2
Russell, J.Q.3
Flavell, R.A.4
Rincón, M.5
Budd, R.C.6
-
23
-
-
0344441706
-
Structure of NFAT bound to DNA as a monomer
-
Stroud, J.; Chen, L. Structure of NFAT bound to DNA as a monomer. J. Mol. Biol. 2003, 334, 1009-1022.
-
(2003)
J. Mol. Biol
, vol.334
, pp. 1009-1022
-
-
Stroud, J.1
Chen, L.2
-
24
-
-
0141507041
-
An asymmetric NFAT1 dimer on a pseudo-palindromic κB-like DNA site
-
Jin , L.; Sliz, P.; Chen, L.; Macian, F.; Rao, A.; Hogan, P. G.; Harrison, S. C. An asymmetric NFAT1 dimer on a pseudo-palindromic κB-like DNA site. Nature Struct. Biol. 2003, 10 , 807-811.
-
(2003)
Nature Struct. Biol
, vol.10
, pp. 807-811
-
-
Jin, L.1
Sliz, P.2
Chen, L.3
Macian, F.4
Rao, A.5
Hogan, P.G.6
Harrison, S.C.7
-
25
-
-
4444320122
-
A field of myocardial-endocardial NFAT signalling underlies heart valve morphogenesis
-
Chang, C. P.; Neilson, J. R.; Bayle, J. H.; Gestwicki, J. E.; Kuo, A.; Stankunas, K.; Graef, I. A.; Crabtree, G. R. A field of myocardial-endocardial NFAT signalling underlies heart valve morphogenesis. Cell 2004, 118, 649-663.
-
(2004)
Cell
, vol.118
, pp. 649-663
-
-
Chang, C.P.1
Neilson, J.R.2
Bayle, J.H.3
Gestwicki, J.E.4
Kuo, A.5
Stankunas, K.6
Graef, I.A.7
Crabtree, G.R.8
-
26
-
-
0030604714
-
The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
-
Ho, I. C.; Hodge, M. R.; Rooney, J. W.; Glimcher, L. H. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 1996, 85 , 973-983.
-
(1996)
Cell
, vol.85
, pp. 973-983
-
-
Ho, I.C.1
Hodge, M.R.2
Rooney, J.W.3
Glimcher, L.H.4
-
27
-
-
0037089575
-
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression
-
Rengarajan, J.; Mowen, K. A.; McBride, K. D.; Smith, E. D.; Singh, H.; Glimcher, L. H. Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J. Exp. Med. 2002, 195, 1003-1012.
-
(2002)
J. Exp. Med
, vol.195
, pp. 1003-1012
-
-
Rengarajan, J.1
Mowen, K.A.2
McBride, K.D.3
Smith, E.D.4
Singh, H.5
Glimcher, L.H.6
-
28
-
-
0037315381
-
Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression
-
Decker, E. L.; Nehmann, N.; Kampen, E.; Eibel, H.; Zipfel, P. F.; Skerka, C. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression. Nucleic Acids Res. 2003, 31 , 911-921.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 911-921
-
-
Decker, E.L.1
Nehmann, N.2
Kampen, E.3
Eibel, H.4
Zipfel, P.F.5
Skerka, C.6
-
29
-
-
0036713123
-
Cooperative interaction between GATA5 and NFATc regulates endothelial-endocardial differentiation of cardiogenic cells
-
Nemer, G.; Nemer, M. Cooperative interaction between GATA5 and NFATc regulates endothelial-endocardial differentiation of cardiogenic cells. Development 2002, 129, 4045-4055.
-
(2002)
Development
, vol.129
, pp. 4045-4055
-
-
Nemer, G.1
Nemer, M.2
-
30
-
-
0037128922
-
Calcineurin-GATA-6 pathway is involved in smooth muscle-specific transcription
-
Wada, H.; Hasegawa, K.; Morimoto, T.; Kakita, T.; Yanazume, T.; Abe, M.; Sasayama, S. Calcineurin-GATA-6 pathway is involved in smooth muscle-specific transcription. J. Cell Biol. 2002, 156, 983-991.
-
(2002)
J. Cell Biol
, vol.156
, pp. 983-991
-
-
Wada, H.1
Hasegawa, K.2
Morimoto, T.3
Kakita, T.4
Yanazume, T.5
Abe, M.6
Sasayama, S.7
-
31
-
-
0034283018
-
Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun
-
Macián, F.; García-Rodríguez, C.; Rao, A. Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun. EMBO J. 2000, 19 , 4783-4795.
-
(2000)
EMBO J
, vol.19
, pp. 4783-4795
-
-
Macián, F.1
García-Rodríguez, C.2
Rao, A.3
-
32
-
-
0032510581
-
The transcription factor NF-ATc is essential for cardiac valve formation
-
Ranger, A. M.; Grusby, M. J.; Hodge, M. R.; Gravallese, E. M.; Charles de la Brousse, F.; Hoey, T.; Mickanin, C.; Baldwin, H. S.; Glimcher, L. H. The transcription factor NF-ATc is essential for cardiac valve formation. Nature 1998, 392, 186-190.
-
(1998)
Nature
, vol.392
, pp. 186-190
-
-
Ranger, A.M.1
Grusby, M.J.2
Hodge, M.R.3
Gravallese, E.M.4
Charles de la Brousse, F.5
Hoey, T.6
Mickanin, C.7
Baldwin, H.S.8
Glimcher, L.H.9
-
33
-
-
0036234543
-
NFAT signalling: Choreographing the social lives of cells
-
Crabtree, G. R.; Olson, E. N. NFAT signalling: choreographing the social lives of cells. Cell 2002, 109(Suppl.), S67-S79.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
Crabtree, G.R.1
Olson, E.N.2
-
34
-
-
0037018145
-
NFAT: Ubiquitous regulator of cell differentiation and adaptation
-
Horsley, V.; Pavlath, G. K. NFAT: ubiquitous regulator of cell differentiation and adaptation. J. Cell Biol. 2002, 156, 771-774.
-
(2002)
J. Cell Biol
, vol.156
, pp. 771-774
-
-
Horsley, V.1
Pavlath, G.K.2
-
35
-
-
0032510493
-
Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
-
de la Pompa, J. L.; Timmerman, L. A.; Takimoto, H.; Yoshida, H.; Elia, A. J.; Samper, E.; Potter, J.; Wakeham, A.; Marengere, L.; Langille, B. L.; Crabtree, G. R.; Mak, T. W. Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum. Nature 1998, 392, 182-186.
-
(1998)
Nature
, vol.392
, pp. 182-186
-
-
de la Pompa, J.L.1
Timmerman, L.A.2
Takimoto, H.3
Yoshida, H.4
Elia, A.J.5
Samper, E.6
Potter, J.7
Wakeham, A.8
Marengere, L.9
Langille, B.L.10
Crabtree, G.R.11
Mak, T.W.12
-
36
-
-
0345830423
-
Calcineurin signaling and NFAT activation in cardiovascular and skeletal muscle development
-
Schulz, R. A.; Yutzey, K. E. Calcineurin signaling and NFAT activation in cardiovascular and skeletal muscle development. Dev. Biol. 2004, 266, 1-16.
-
(2004)
Dev. Biol
, vol.266
, pp. 1-16
-
-
Schulz, R.A.1
Yutzey, K.E.2
-
37
-
-
0346634892
-
Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis
-
Hove, J. R.; Köster, R. W.; Forouhar, A. S.; Acevedo-Bolton, G.; Fraser, S. E.; Gharib, M. Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis. Nature 2003, 421, 172-177.
-
(2003)
Nature
, vol.421
, pp. 172-177
-
-
Hove, J.R.1
Köster, R.W.2
Forouhar, A.S.3
Acevedo-Bolton, G.4
Fraser, S.E.5
Gharib, M.6
-
38
-
-
0037449818
-
NFATc1 mediates vascular endothelial growth factor-induced proliferation of human pulmonary valve endothelial cells
-
Johnson, E. N.; Lee, Y. M.; Sander, T. L.; Rabkin, E.; Schoen, F. J.; Kaushal, S.; Bischoff, J. NFATc1 mediates vascular endothelial growth factor-induced proliferation of human pulmonary valve endothelial cells. J. Biol. Chem. 2003, 278, 1686-1692.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 1686-1692
-
-
Johnson, E.N.1
Lee, Y.M.2
Sander, T.L.3
Rabkin, E.4
Schoen, F.J.5
Kaushal, S.6
Bischoff, J.7
-
39
-
-
4444320122
-
A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesis
-
Chang, C. P.; Neilson, J. R.; Bayle, J. H.; Gestwicki, J. E.; Kuo, A.; Stankunas, K.; Graef, I. A.; Crabtree, G. R. A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesis. Cell 2004, 118, 649-663.
-
(2004)
Cell
, vol.118
, pp. 649-663
-
-
Chang, C.P.1
Neilson, J.R.2
Bayle, J.H.3
Gestwicki, J.E.4
Kuo, A.5
Stankunas, K.6
Graef, I.A.7
Crabtree, G.R.8
-
40
-
-
0031694618
-
Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells
-
Abbott, K. L.; Friday, B. B.; Thaloor, D.; Murphy, T. J.; Pavlath, G. K. Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells. Mol. Biol. Cell 1998, 9, 2905-2916.
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 2905-2916
-
-
Abbott, K.L.1
Friday, B.B.2
Thaloor, D.3
Murphy, T.J.4
Pavlath, G.K.5
-
41
-
-
0033838874
-
A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression
-
Delling, U.; Tureckova, J.; Lim, H. W.; De Windt, L. J.; Rotwein, P.; Molkentin, J. D. A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression. Mol. Cell. Biol. 2000, 20 , 6600-6611.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 6600-6611
-
-
Delling, U.1
Tureckova, J.2
Lim, H.W.3
De Windt, L.J.4
Rotwein, P.5
Molkentin, J.D.6
-
43
-
-
0035897418
-
Regulation of the growth of multinucleated muscle cells by an NFATc2-dependent pathway
-
Horsley, V.; Friday, B. B.; Matteson, S.; Kegley, K. M.; Gephart, J.; Pavlath, G. K. Regulation of the growth of multinucleated muscle cells by an NFATc2-dependent pathway. J. Cell Biol. 2001, 153, 329-338.
-
(2001)
J. Cell Biol
, vol.153
, pp. 329-338
-
-
Horsley, V.1
Friday, B.B.2
Matteson, S.3
Kegley, K.M.4
Gephart, J.5
Pavlath, G.K.6
-
44
-
-
0037726553
-
IL-4 acts as a myoblast recruitment factor during mammalian muscle growth
-
Horsley, V.; Jansen, K. M.; Mills, S. T.; Pavlath, G. K. IL-4 acts as a myoblast recruitment factor during mammalian muscle growth. Cell 2003, 113, 483-494.
-
(2003)
Cell
, vol.113
, pp. 483-494
-
-
Horsley, V.1
Jansen, K.M.2
Mills, S.T.3
Pavlath, G.K.4
-
45
-
-
0037437175
-
Prostaglandin F2α stimulates growth of skeletal muscle cells via an NFATC2-dependent pathway
-
Horsley, V.; Pavlath, G. K. Prostaglandin F2α stimulates growth of skeletal muscle cells via an NFATC2-dependent pathway. J. Cell Biol. 2003, 161, 111-118.
-
(2003)
J. Cell Biol
, vol.161
, pp. 111-118
-
-
Horsley, V.1
Pavlath, G.K.2
-
46
-
-
0033527021
-
2+-dependent calcineurin signaling pathway
-
2+-dependent calcineurin signaling pathway. Nature 1999, 400, 576-581.
-
(1999)
Nature
, vol.400
, pp. 576-581
-
-
Semsarian, C.1
Wu, M.J.2
Ju, Y.K.3
Marciniec, T.4
Yeoh, T.5
Allen, D.G.6
Harvey, R.P.7
Graham, R.M.8
-
47
-
-
18744366041
-
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
-
Takayanagi, H.; Kim, S.; Koga, T.; Nishina, H.; Isshiki, M.; Yoshida, H.; Saiura, A.; Isobe, M.; Yokochi, T.; Inoue, J. I.; Wagner, E. F.; Mak, T. W.; Kodama, T.; Taniguchi, T. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev. Cell 2002, 3, 889-901.
-
(2002)
Dev. Cell
, vol.3
, pp. 889-901
-
-
Takayanagi, H.1
Kim, S.2
Koga, T.3
Nishina, H.4
Isshiki, M.5
Yoshida, H.6
Saiura, A.7
Isobe, M.8
Yokochi, T.9
Inoue, J.I.10
Wagner, E.F.11
Mak, T.W.12
Kodama, T.13
Taniguchi, T.14
-
48
-
-
0037174944
-
Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator
-
Ishida, N.; Hayashi, K.; Hoshijima, M.; Ogawa, T.; Koga, S.; Miyatake, Y.; Kumegawa, M.; Kimura, T.; Takeya, T. Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator. J. Biol. Chem. 2002, 277, 41147-41156.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 41147-41156
-
-
Ishida, N.1
Hayashi, K.2
Hoshijima, M.3
Ogawa, T.4
Koga, S.5
Miyatake, Y.6
Kumegawa, M.7
Kimura, T.8
Takeya, T.9
-
49
-
-
4344697340
-
Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation
-
Ikeda, F.; Nishimura, R.; Matsubara, T.; Tanaka, S.; Inoue, J. I.; Reddy, S. V.; Hata, K.; Yamashita, K.; Hiraga, T.; Watanabe, T.; Kukita, T.; Yoshioka, K.; Rao, A.; Yoneda, T. Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. J. Clin. Invest. 2004, 114, 475-484.
-
(2004)
J. Clin. Invest
, vol.114
, pp. 475-484
-
-
Ikeda, F.1
Nishimura, R.2
Matsubara, T.3
Tanaka, S.4
Inoue, J.I.5
Reddy, S.V.6
Hata, K.7
Yamashita, K.8
Hiraga, T.9
Watanabe, T.10
Kukita, T.11
Yoshioka, K.12
Rao, A.13
Yoneda, T.14
-
50
-
-
14044249546
-
Convergent signaling by acidosis and receptor activator of NF-κB ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts
-
Komarova, S. V.; Pereverzev, A.; Shum, J. W.; Sims, S. M.; Dixon, S. J. Convergent signaling by acidosis and receptor activator of NF-κB ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts. Proc. Natl. Acad. Sci. USA 2005, 102, 2643-2648.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2643-2648
-
-
Komarova, S.V.1
Pereverzev, A.2
Shum, J.W.3
Sims, S.M.4
Dixon, S.J.5
-
51
-
-
23844515714
-
NFAT and osterix cooperatively regulate bone formation
-
Koga, T.; Matsui, Y.; Asagiri, M.; Kodama, T.; de Crombrugghe, B.; Nakashima, K.; Takayanagi, H. NFAT and osterix cooperatively regulate bone formation. Nat. Med. 2005, 11 , 880-885.
-
(2005)
Nat. Med
, vol.11
, pp. 880-885
-
-
Koga, T.1
Matsui, Y.2
Asagiri, M.3
Kodama, T.4
de Crombrugghe, B.5
Nakashima, K.6
Takayanagi, H.7
-
52
-
-
30344459696
-
Carcinogenic effect of nickel compounds
-
Lu, H.; Shi, X.; Costa, M.; Huang, C. Carcinogenic effect of nickel compounds. Mol. Cell. Biochem. 2005, 279, 45-67.
-
(2005)
Mol. Cell. Biochem
, vol.279
, pp. 45-67
-
-
Lu, H.1
Shi, X.2
Costa, M.3
Huang, C.4
-
53
-
-
0034737733
-
Involvement of nuclear factor of activated T cells activation in UV response. Evidence from cell culture and transgenic mice
-
Huang, C.; Mattjus, P.; Ma, W. Y.; Rincon, M.; Chen, N. Y.; Brown, R. E.; Dong, Z. Involvement of nuclear factor of activated T cells activation in UV response. Evidence from cell culture and transgenic mice. J. Biol. Chem. 2000, 275, 9143-9149.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 9143-9149
-
-
Huang, C.1
Mattjus, P.2
Ma, W.Y.3
Rincon, M.4
Chen, N.Y.5
Brown, R.E.6
Dong, Z.7
-
54
-
-
33746831980
-
NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells
-
Yan, Y.; Li, J.; Ouyang, W.; Ma, Q.; Hu, Y.; Zhang, D.; Ding, J.; Qu, Q.; Subbaramaiah, K.; Huang, C. NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells. J. Cell Sci. 2006, 119(Pt 14), 2985-2994.
-
(2006)
J. Cell Sci
, vol.119
, Issue.PART 14
, pp. 2985-2994
-
-
Yan, Y.1
Li, J.2
Ouyang, W.3
Ma, Q.4
Hu, Y.5
Zhang, D.6
Ding, J.7
Qu, Q.8
Subbaramaiah, K.9
Huang, C.10
-
55
-
-
15744397205
-
Expression and function of the nuclear factor of activated T cells in colon carcinoma cells
-
Duque, J.; Fresno, M.; Iniguez, M. A. Expression and function of the nuclear factor of activated T cells in colon carcinoma cells. J. Biol. Chem. 2005, 289, 8686-8693.
-
(2005)
J. Biol. Chem
, vol.289
, pp. 8686-8693
-
-
Duque, J.1
Fresno, M.2
Iniguez, M.A.3
-
56
-
-
4644223413
-
Effect of phosphodiesterase 4 inhibitors on NFAT-dependent cyclooxygenase-2 expression in human T lymphocytes
-
Jimenez, J. L.; Iniguez, M. A.; Munoz-Fernández, M. A.; Fresno, M. Effect of phosphodiesterase 4 inhibitors on NFAT-dependent cyclooxygenase-2 expression in human T lymphocytes. Cell Signal. 2004, 16 , 1363-1373.
-
(2004)
Cell Signal
, vol.16
, pp. 1363-1373
-
-
Jimenez, J.L.1
Iniguez, M.A.2
Munoz-Fernández, M.A.3
Fresno, M.4
-
57
-
-
0027272061
-
Anti-tumor-promoting action of FK506, a potent immunosuppressive agent
-
Jiang, H.; Yamamoto, S.; Nishikawa, K.; Kato, R. Anti-tumor-promoting action of FK506, a potent immunosuppressive agent. Carcinogenesis 1993, 14 , 67-71.
-
(1993)
Carcinogenesis
, vol.14
, pp. 67-71
-
-
Jiang, H.1
Yamamoto, S.2
Nishikawa, K.3
Kato, R.4
-
58
-
-
0029102881
-
Ultraviolet B irradiation promotes tumorigenic and metastatic properties in primary cutaneous melanoma via induction of interleukin 8
-
Singh, R. K.; Gutman, M.; Reich, R.; Bar-Eli, M. Ultraviolet B irradiation promotes tumorigenic and metastatic properties in primary cutaneous melanoma via induction of interleukin 8. Cancer Res. 1995, 55 , 3669-3674.
-
(1995)
Cancer Res
, vol.55
, pp. 3669-3674
-
-
Singh, R.K.1
Gutman, M.2
Reich, R.3
Bar-Eli, M.4
-
59
-
-
3042743983
-
Genomic DNA-chip hybridization reveals a higher incidence of genomic amplifications in pancreatic cancer than conventional comparative genomic hybridization and leads to the identification of novel candidate genes
-
Holzmann, K.; Kohlhammer, H.; Schwaenen, C.; Wessendorf, S.; Kestler, H. A.; Schwoerer, A.; Rau, B.; Radlwimmer, B.; Döhner, H.; Lichter, P.; Gress, T.; Bentz, M. Genomic DNA-chip hybridization reveals a higher incidence of genomic amplifications in pancreatic cancer than conventional comparative genomic hybridization and leads to the identification of novel candidate genes. Cancer Res. 2004, 64 , 4428-4433.
-
(2004)
Cancer Res
, vol.64
, pp. 4428-4433
-
-
Holzmann, K.1
Kohlhammer, H.2
Schwaenen, C.3
Wessendorf, S.4
Kestler, H.A.5
Schwoerer, A.6
Rau, B.7
Radlwimmer, B.8
Döhner, H.9
Lichter, P.10
Gress, T.11
Bentz, M.12
-
60
-
-
0035890815
-
Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide
-
Huang, C.; Li, J.; Costa, M.; Zhang, Z.; Leonard, S. S.; Castranova, V.; Vallyathan, V.; Ju, G.; Shi, X. Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide. Cancer Res. 2001, 61 , 8051-8057.
-
(2001)
Cancer Res
, vol.61
, pp. 8051-8057
-
-
Huang, C.1
Li, J.2
Costa, M.3
Zhang, Z.4
Leonard, S.S.5
Castranova, V.6
Vallyathan, V.7
Ju, G.8
Shi, X.9
-
61
-
-
4243334765
-
Involvement of hydrogen peroxide in asbestos-induced NFAT activation
-
Li, J.; Huang, B.; Shi, X.; Castranova, V.; Vallyathan, V.; Huang, C. Involvement of hydrogen peroxide in asbestos-induced NFAT activation. Mol. Cell. Biochem. 2002, 234/235, 161-168.
-
(2002)
Mol. Cell. Biochem
, vol.234-235
, pp. 161-168
-
-
Li, J.1
Huang, B.2
Shi, X.3
Castranova, V.4
Vallyathan, V.5
Huang, C.6
-
62
-
-
32844468634
-
Calcineurin inhibitors decreases DNA repair and apoptosis in human keratinocytes following ultraviolet B irradiation
-
Yarosh, D. B.; Pena, A. V.; Nay, S. L.; Canning, M. T.; Brown, D. A. Calcineurin inhibitors decreases DNA repair and apoptosis in human keratinocytes following ultraviolet B irradiation. J. Invest. Dermatol. 2005, 125, 1020-1025.
-
(2005)
J. Invest. Dermatol
, vol.125
, pp. 1020-1025
-
-
Yarosh, D.B.1
Pena, A.V.2
Nay, S.L.3
Canning, M.T.4
Brown, D.A.5
-
63
-
-
27844539302
-
Low UVA doses activates the transcription factor NFAT in human fibroblasts by a calcium-calcineurin pathway
-
Mazière, C.; Morlière, P.; Louandre, C.; Conte, M. A.; Gomilla, C.; Santus, R.; Antonicelli, F.; Hornebeck, W.; Mazière, J. C. Low UVA doses activates the transcription factor NFAT in human fibroblasts by a calcium-calcineurin pathway. Free Radic. Biol. Med. 2005, 39 , 1629-1637.
-
(2005)
Free Radic. Biol. Med
, vol.39
, pp. 1629-1637
-
-
Mazière, C.1
Morlière, P.2
Louandre, C.3
Conte, M.A.4
Gomilla, C.5
Santus, R.6
Antonicelli, F.7
Hornebeck, W.8
Mazière, J.C.9
-
64
-
-
0742306716
-
Molecular mechanisms of arsenic carcinogenesis
-
Huang, C.; Ke, Q.; Costa M.; Shi, X. Molecular mechanisms of arsenic carcinogenesis. Mol. Cell. Biochem., 2004, 255, 57-66.
-
(2004)
Mol. Cell. Biochem
, vol.255
, pp. 57-66
-
-
Huang, C.1
Ke, Q.2
Costa, M.3
Shi, X.4
-
65
-
-
0023832768
-
Transfer by pro gene transfection of tumor promoter-sensitive phenotype to promotion-insensitive JB6 cells
-
Colburn, N. H.; Smith, B. M.; Wendel, E. J.; Dowjat, W. K.; Shimada, T. Transfer by pro gene transfection of tumor promoter-sensitive phenotype to promotion-insensitive JB6 cells. Cancer Res. 1988, 48 , 1195-1200.
-
(1988)
Cancer Res
, vol.48
, pp. 1195-1200
-
-
Colburn, N.H.1
Smith, B.M.2
Wendel, E.J.3
Dowjat, W.K.4
Shimada, T.5
-
66
-
-
0037030518
-
STAT3 activation is required for interleukin-6 induced transformation in tumor-promotion sensitive mouse skin epithelial cells
-
Yu, C. Y.; Wang, L.; Khaletskiy, A.; Farrar, W. L.; Larner, A.; Colburn, N. H.; Li, J. J. STAT3 activation is required for interleukin-6 induced transformation in tumor-promotion sensitive mouse skin epithelial cells. Oncogene 2002, 21 , 3949-3960.
-
(2002)
Oncogene
, vol.21
, pp. 3949-3960
-
-
Yu, C.Y.1
Wang, L.2
Khaletskiy, A.3
Farrar, W.L.4
Larner, A.5
Colburn, N.H.6
Li, J.J.7
-
67
-
-
0025814732
-
Benzo[a]pyrene-induced skin damage and tumor promotion in the mouse
-
Albert R. E.; Miller, M. L.; Cody, T.; Andringa, A.; Shukla, R.; Baxter, C. S. Benzo[a]pyrene-induced skin damage and tumor promotion in the mouse. Carcinogenesis 1991, 12 , 1273-1280.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1273-1280
-
-
Albert, R.E.1
Miller, M.L.2
Cody, T.3
Andringa, A.4
Shukla, R.5
Baxter, C.S.6
-
68
-
-
35148855014
-
Direct Evidence for the Critical Role of NFAT3 in Benzo[a]pyrene Diol-Epoxide-Induced Cell Transformation through Mediation of Inflammatory Cytokine TNFa in Mouse Epidermal Cl41 Cells
-
revised
-
Ouyang, W.; Hu, Y.; Li J.; Ding, M.; Lu, Y.; Zhang, D.; Yan, Y.; Song, L.; Qu, Q.; Desai, D.; Amin, S.; Huang, C. Direct Evidence for the Critical Role of NFAT3 in Benzo[a]pyrene Diol-Epoxide-Induced Cell Transformation through Mediation of Inflammatory Cytokine TNFa in Mouse Epidermal Cl41 Cells. Carcinogenesis, revised.
-
Carcinogenesis
-
-
Ouyang, W.1
Hu, Y.2
Li, J.3
Ding, M.4
Lu, Y.5
Zhang, D.6
Yan, Y.7
Song, L.8
Qu, Q.9
Desai, D.10
Amin, S.11
Huang, C.12
-
69
-
-
33748297452
-
NFAT3 is required for EGF-induced COX-2 transcription, but neither iNOS transcription nor cell transformation in Cl 41 Cells
-
Li, J.; Lu, H.; Huang, C. NFAT3 is required for EGF-induced COX-2 transcription, but neither iNOS transcription nor cell transformation in Cl 41 Cells. Mol. Cell. Biochem. 2006, 289(1-2), 73-82.
-
(2006)
Mol. Cell. Biochem
, vol.289
, Issue.1-2
, pp. 73-82
-
-
Li, J.1
Lu, H.2
Huang, C.3
-
70
-
-
33746848336
-
Knockdown of NFAT3 blocked TPA-induced COX-2 and iNOS expression, and enhanced cell transformation in Cl41 cells
-
Li, J.; Song, L.; Zhang, D.; Wei, L.; Huang, C. Knockdown of NFAT3 blocked TPA-induced COX-2 and iNOS expression, and enhanced cell transformation in Cl41 cells. J. Cell. Biochem., 2006, 99 (4), 1010-1020.
-
(2006)
J. Cell. Biochem
, vol.99
, Issue.4
, pp. 1010-1020
-
-
Li, J.1
Song, L.2
Zhang, D.3
Wei, L.4
Huang, C.5
-
71
-
-
4444361445
-
Nitric oxide does not mediate but inhibits transformation and cancer phenotype
-
Dhar, A.; Brindley, J. M.; Stark, C.; Citro, M. L.; Keefer, L. K.; Colburn, N. H. Nitric oxide does not mediate but inhibits transformation and cancer phenotype. Mol. Cancer Ther. 2003, 2, 1285-1293.
-
(2003)
Mol. Cancer Ther
, vol.2
, pp. 1285-1293
-
-
Dhar, A.1
Brindley, J.M.2
Stark, C.3
Citro, M.L.4
Keefer, L.K.5
Colburn, N.H.6
-
72
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D.; Weinberg, R. A. The hallmarks of cancer. Cell 2000, 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
74
-
-
17844402720
-
Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation
-
Mammucari, C.; di Vignano, A. T.; Sharov, A. A.; Neilson, J.; Havrda, M. C.; Roop, D. R.; Botchkarev, V. A.; Crabtree, G. R.; Dotto, G. P. Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation. Dev. Cell 2005, 8, 665-676.
-
(2005)
Dev. Cell
, vol.8
, pp. 665-676
-
-
Mammucari, C.1
di Vignano, A.T.2
Sharov, A.A.3
Neilson, J.4
Havrda, M.C.5
Roop, D.R.6
Botchkarev, V.A.7
Crabtree, G.R.8
Dotto, G.P.9
-
75
-
-
0036864625
-
NFATc2-mediated repression of cyclin-dependent kinase 4 expression
-
Baksh, S.; Widlund, H. R.; Frazer-Abel, A. A.; Du, J.; Fosmire, S.; Fisher, D. E.; DeCaprio, J. A.; Modiano, J. F.; Burakoff, S. J. NFATc2-mediated repression of cyclin-dependent kinase 4 expression. Mol. Cell 2002, 10 , 1071-1081.
-
(2002)
Mol. Cell
, vol.10
, pp. 1071-1081
-
-
Baksh, S.1
Widlund, H.R.2
Frazer-Abel, A.A.3
Du, J.4
Fosmire, S.5
Fisher, D.E.6
DeCaprio, J.A.7
Modiano, J.F.8
Burakoff, S.J.9
-
76
-
-
0033564697
-
CDK inhibitors: Positive and negative regulators of G1-phase progression
-
Sherr, C. J.; Roberts, J. M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 1999, 13 , 1501-1512.
-
(1999)
Genes Dev
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
77
-
-
0036884463
-
NFATC2 transcription factor regulates cell cycle progression during lymphocyte activation: Evidence of its involvement in the control of cyclin gene expression
-
Caetano, M. S.; Vieira-de-Abreu, A.; Teixeira, L. K.; Werneck, M. B. F.; Barcinski, M. A.; Viola, J. P. B. NFATC2 transcription factor regulates cell cycle progression during lymphocyte activation: evidence of its involvement in the control of cyclin gene expression. FASEB J. 2002, 16 , 1940-1942.
-
(2002)
FASEB J
, vol.16
, pp. 1940-1942
-
-
Caetano, M.S.1
Vieira-de-Abreu, A.2
Teixeira, L.K.3
Werneck, M.B.F.4
Barcinski, M.A.5
Viola, J.P.B.6
-
78
-
-
0031933037
-
Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc
-
Ranger, A. M.; Hodge, M. R.;Gravallese, E. M.; Oukka, M.; Davidson, L.; Alt, F. W.; Charles de la Brousse, F.; Hoey, T.; Grusby, M.; Glimcher, L. H. Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc. Immunity 1998, 8, 125-134.
-
(1998)
Immunity
, vol.8
, pp. 125-134
-
-
Ranger, A.M.1
Hodge, M.R.2
Gravallese, E.M.3
Oukka, M.4
Davidson, L.5
Alt, F.W.6
Charles de la Brousse, F.7
Hoey, T.8
Grusby, M.9
Glimcher, L.H.10
-
79
-
-
0031951071
-
The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production
-
Yoshida, H.; Nishina, H.; Takimoto, H.; Marengere, L. E.; Wakeham, A. C.; Bouchard, D.; Kong, Y. Y.; Ohteki, T.; Shahinian, A.; Bachmann, M.; Ohashi, P. S.; Penninger, J. M.; Crabtree, G. R.; Mak, T. W. The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production. Immunity 1998, 8, 115-124.
-
(1998)
Immunity
, vol.8
, pp. 115-124
-
-
Yoshida, H.1
Nishina, H.2
Takimoto, H.3
Marengere, L.E.4
Wakeham, A.C.5
Bouchard, D.6
Kong, Y.Y.7
Ohteki, T.8
Shahinian, A.9
Bachmann, M.10
Ohashi, P.S.11
Penninger, J.M.12
Crabtree, G.R.13
Mak, T.W.14
-
80
-
-
0037931834
-
-
Neal, J. W.; Clipstone, N. A. A constitutively active NFATc1 mutant induces a transformed phenotype in 3T3-L1 fibroblasts. J. Biol. Chem. 2003, 278, 17246-17254.
-
Neal, J. W.; Clipstone, N. A. A constitutively active NFATc1 mutant induces a transformed phenotype in 3T3-L1 fibroblasts. J. Biol. Chem. 2003, 278, 17246-17254.
-
-
-
-
81
-
-
18444365894
-
Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis
-
Chuvpilo, S.; Jankevics, E.; Tyrsin, D.; Akimzhanov, A.; Moroz, D.; Jha, M. K.; Schulze-Luehrmann, J.; Santner-Nanan, B.; Feoktistova, E.; König, T.; Avots, A.; Schmitt, E.; Berberich-Siebelt, F.; Schimpl, A.; Serfling, E. Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis. Immunity 2002, 16 , 881-895.
-
(2002)
Immunity
, vol.16
, pp. 881-895
-
-
Chuvpilo, S.1
Jankevics, E.2
Tyrsin, D.3
Akimzhanov, A.4
Moroz, D.5
Jha, M.K.6
Schulze-Luehrmann, J.7
Santner-Nanan, B.8
Feoktistova, E.9
König, T.10
Avots, A.11
Schmitt, E.12
Berberich-Siebelt, F.13
Schimpl, A.14
Serfling, E.15
-
82
-
-
14144251429
-
Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis
-
Jayanthi, S.; Deng, X.; Ladenheim, B.; McCoy, M. T.; Cluster, A.; Cai, N. S.; Cadet, J. L. Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis. Proc. Natl. Acad. Sci. USA 2005, 102, 868-873.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 868-873
-
-
Jayanthi, S.1
Deng, X.2
Ladenheim, B.3
McCoy, M.T.4
Cluster, A.5
Cai, N.S.6
Cadet, J.L.7
-
83
-
-
23844477888
-
The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway
-
Rivera, A.; Maxwell, S. A. The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway. J. Biol. Chem. 2005, 280, 29346-29354.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 29346-29354
-
-
Rivera, A.1
Maxwell, S.A.2
-
84
-
-
0031028816
-
Cyclosporin A, an immunosuppressive drug, induces programmed cell death in rat C6 glioma cells by a mechanism that involves the AP-1 transcription factor
-
Mosieniak, G.; Figiel, I.; Kaminska, B. Cyclosporin A, an immunosuppressive drug, induces programmed cell death in rat C6 glioma cells by a mechanism that involves the AP-1 transcription factor. J. Neurochem. 1997, 68 , 1142-1149.
-
(1997)
J. Neurochem
, vol.68
, pp. 1142-1149
-
-
Mosieniak, G.1
Figiel, I.2
Kaminska, B.3
-
85
-
-
28444491798
-
Constitutive NF-κB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival
-
Pham, L. V.; Tamayo, A. T.; Yoshimura, L. C.; Lin-Lee, Y. C.; Ford, R. J. Constitutive NF-κB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival. Blood 2005, 106, 3940-3947.
-
(2005)
Blood
, vol.106
, pp. 3940-3947
-
-
Pham, L.V.1
Tamayo, A.T.2
Yoshimura, L.C.3
Lin-Lee, Y.C.4
Ford, R.J.5
-
86
-
-
33744486857
-
Constitutive NF-κB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B cell lymphomas
-
in press
-
Fu, L.; Lin-Lee, Y. C.; Pham, L. V.; Tamayo, A.; Yoshimura, L.; Ford, R. J. Constitutive NF-κB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B cell lymphomas. Blood in press.
-
Blood
-
-
Fu, L.1
Lin-Lee, Y.C.2
Pham, L.V.3
Tamayo, A.4
Yoshimura, L.5
Ford, R.J.6
-
87
-
-
0032167830
-
The transcription factor NFAT4 is involved in the generation and survival of T cells
-
Oukka, M.; Ho, I. C.; Charles de la Brousse, F.; Hoey, T.; Grusby, M. J.; Glimcher, L. H. The transcription factor NFAT4 is involved in the generation and survival of T cells. Immunity 1998, 9, 295-304.
-
(1998)
Immunity
, vol.9
, pp. 295-304
-
-
Oukka, M.1
Ho, I.C.2
Charles de la Brousse, F.3
Hoey, T.4
Grusby, M.J.5
Glimcher, L.H.6
-
88
-
-
0035809312
-
Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: Roles of the nuclear factor of activated T cells and cyclooxygenase-2
-
Hernández, G. L.; Volpert, O. V.; Íniguez, M. A.; Lorenzo, E.; Martínez-Martínez, S.; Grau, R.; Fresno, M.; Redondo, J. M. Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase-2. J. Exp. Med. 2001, 193, 607-620.
-
(2001)
J. Exp. Med
, vol.193
, pp. 607-620
-
-
Hernández, G.L.1
Volpert, O.V.2
Íniguez, M.A.3
Lorenzo, E.4
Martínez-Martínez, S.5
Grau, R.6
Fresno, M.7
Redondo, J.M.8
-
89
-
-
0029837761
-
How tumors become angiogenic
-
Bouck, N.; Stellmach, V.; Hsu, S. C. How tumors become angiogenic. Adv. Cancer Res. 1996, 69 , 135-174.
-
(1996)
Adv. Cancer Res
, vol.69
, pp. 135-174
-
-
Bouck, N.1
Stellmach, V.2
Hsu, S.C.3
-
90
-
-
2942657484
-
Nuclear factor of activated T cells balances angiogenesis activation and inhibition
-
Zaichuk, T. A.; Shroff, E. H.; Emmanuel, R.; Filleur, S.; Nelius, T.; Volpert, O. V. Nuclear factor of activated T cells balances angiogenesis activation and inhibition. J. Exp. Med. 2004, 199, 1513-1522.
-
(2004)
J. Exp. Med
, vol.199
, pp. 1513-1522
-
-
Zaichuk, T.A.1
Shroff, E.H.2
Emmanuel, R.3
Filleur, S.4
Nelius, T.5
Volpert, O.V.6
-
91
-
-
0036104828
-
Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor
-
Volpert, O. V.; Zaichuk, T. A.; Zhou, W.; Reiher, F.; Ferguson, T. A.; Stuart, P. M.; Amin, M.; Bouck, N. P. Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor. Nat. Med. 2002, 8, 349-357.
-
(2002)
Nat. Med
, vol.8
, pp. 349-357
-
-
Volpert, O.V.1
Zaichuk, T.A.2
Zhou, W.3
Reiher, F.4
Ferguson, T.A.5
Stuart, P.M.6
Amin, M.7
Bouck, N.P.8
-
92
-
-
0029870954
-
The war on cancer
-
Sporn, M. B. The war on cancer. Lancet 1996, 347, 1377-1381.
-
(1996)
Lancet
, vol.347
, pp. 1377-1381
-
-
Sporn, M.B.1
-
93
-
-
0036308285
-
The role of NFAT transcription factors in integrin-mediated carcinoma invasion
-
Jauliac, S.; López-Rodriguez, C.; Shaw, L. M.; Brown, L. F.; Rao, A.; Toker, A. The role of NFAT transcription factors in integrin-mediated carcinoma invasion. Nat. Cell Biol. 2002, 4, 540-544.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 540-544
-
-
Jauliac, S.1
López-Rodriguez, C.2
Shaw, L.M.3
Brown, L.F.4
Rao, A.5
Toker, A.6
-
94
-
-
27944446105
-
Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT
-
Yoeli-Lerner, M.; Yiu, G. K.; Rabinovitz, I.; Erhardt, P.; Jauliac, S.; Toker, A. Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT. Mol. Cell 2005, 20 , 539-550.
-
(2005)
Mol. Cell
, vol.20
, pp. 539-550
-
-
Yoeli-Lerner, M.1
Yiu, G.K.2
Rabinovitz, I.3
Erhardt, P.4
Jauliac, S.5
Toker, A.6
-
95
-
-
33744948986
-
NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2
-
Yiu, G. K.; Toker, A. NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2. J. Biol. Chem. 2006, 281(18), 12210-12217.
-
(2006)
J. Biol. Chem
, vol.281
, Issue.18
, pp. 12210-12217
-
-
Yiu, G.K.1
Toker, A.2
-
96
-
-
27644587860
-
NFATc3 deficiency may contribute to the development of mammary gland adenocarcinoma in aging female mice
-
Lee, H.; Chouinard, L.; Bonin, M.; Michel, R. N. NFATc3 deficiency may contribute to the development of mammary gland adenocarcinoma in aging female mice. Mol. Carcinogen. 2005, 44 , 219-222.
-
(2005)
Mol. Carcinogen
, vol.44
, pp. 219-222
-
-
Lee, H.1
Chouinard, L.2
Bonin, M.3
Michel, R.N.4
-
97
-
-
27744591989
-
A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus
-
Glud, S. Z.; Sorensen, A. B.; Andrulis, M.; Wang, B.; Kondo, E.; Jessen, R.; Krenacs, L.; Stelkovics, E.; Wabl, M.; Serfling, E.; Palmetshofer, A.; Pedersen, F. S. A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus. Blood 2005, 106, 3546-3552.
-
(2005)
Blood
, vol.106
, pp. 3546-3552
-
-
Glud, S.Z.1
Sorensen, A.B.2
Andrulis, M.3
Wang, B.4
Kondo, E.5
Jessen, R.6
Krenacs, L.7
Stelkovics, E.8
Wabl, M.9
Serfling, E.10
Palmetshofer, A.11
Pedersen, F.S.12
-
98
-
-
0034598356
-
The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis
-
Ranger, A. M.; Gerstenfeld, L. C.; Wang, J.; Kon, T.; Bae, H.; Gravallese, E. M.; Glimcher, M. J.; Glimcher, L. H. The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis. J. Exp. Med. 2000, 191, 9-22.
-
(2000)
J. Exp. Med
, vol.191
, pp. 9-22
-
-
Ranger, A.M.1
Gerstenfeld, L.C.2
Wang, J.3
Kon, T.4
Bae, H.5
Gravallese, E.M.6
Glimcher, M.J.7
Glimcher, L.H.8
-
99
-
-
0029882657
-
An enhanced immune response in mice lacking the transcription factor NFAT1
-
Xanthoudakis, S.; Viola, J. P.; Shaw, K. T.; Luo, C.; Wallace, J. D.; Bozza, P. T.; Luk, D. C.; Curran, T.; Rao, A. An enhanced immune response in mice lacking the transcription factor NFAT1. Science 1996, 272, 892-895.
-
(1996)
Science
, vol.272
, pp. 892-895
-
-
Xanthoudakis, S.1
Viola, J.P.2
Shaw, K.T.3
Luo, C.4
Wallace, J.D.5
Bozza, P.T.6
Luk, D.C.7
Curran, T.8
Rao, A.9
-
100
-
-
0030002617
-
Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice
-
Hodge, M. R.; Ranger, A. M.; Charles de la Brousse, F.; Hoey, T.; Grusby, M. J.; Glimcher, L. H. Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice. Immunity 1996, 4, 397-405.
-
(1996)
Immunity
, vol.4
, pp. 397-405
-
-
Hodge, M.R.1
Ranger, A.M.2
Charles de la Brousse, F.3
Hoey, T.4
Grusby, M.J.5
Glimcher, L.H.6
-
101
-
-
2442714017
-
Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules
-
Roehrl, M. H. A.; Kang, S.; Aramburu, J.; Wagner, G.; Rao, A.; Hogan, P. G. Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules. Proc. Natl. Acad. Sci. USA 2004, 101, 7554-7559.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7554-7559
-
-
Roehrl, M.H.A.1
Kang, S.2
Aramburu, J.3
Wagner, G.4
Rao, A.5
Hogan, P.G.6
-
102
-
-
0033698581
-
Manipulating immune responses with immunosuppressive agents that target NFAT
-
Kiani, A.; Rao, A.; Aramburu, J. Manipulating immune responses with immunosuppressive agents that target NFAT. Immunity 2000, 12 , 359-372.
-
(2000)
Immunity
, vol.12
, pp. 359-372
-
-
Kiani, A.1
Rao, A.2
Aramburu, J.3
-
103
-
-
2942632790
-
Chemical genetics to identify FNAT inhibitors: Potential of targeting calcium mobilization in immunosuppression
-
Venkatesh, N.; Feng, Y.; DeDecker, B.; Yacono, P.; Golan, D.; Mitchison, T.; McKeon, F. Chemical genetics to identify FNAT inhibitors: potential of targeting calcium mobilization in immunosuppression. Proc. Nat. Acad. Sci. USA 2004, 101, 8969-8974.
-
(2004)
Proc. Nat. Acad. Sci. USA
, vol.101
, pp. 8969-8974
-
-
Venkatesh, N.1
Feng, Y.2
DeDecker, B.3
Yacono, P.4
Golan, D.5
Mitchison, T.6
McKeon, F.7
-
104
-
-
0032039075
-
Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT
-
Aramburu, J.; García-Cozár, F.; Raghavan, A.; Okamura, H.; Rao, A.; Hogan, P. G. Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT. Mol. Cell 1998, 1, 627-637.
-
(1998)
Mol. Cell
, vol.1
, pp. 627-637
-
-
Aramburu, J.1
García-Cozár, F.2
Raghavan, A.3
Okamura, H.4
Rao, A.5
Hogan, P.G.6
-
105
-
-
0032849010
-
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A
-
Aramburu, J.; Yaffe, M. B.; López-Rodríguez, C.; Cantley, L. C.; Hogan, P. G.; Rao, A. Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A. Science 1999, 285, 2129-2133.
-
(1999)
Science
, vol.285
, pp. 2129-2133
-
-
Aramburu, J.1
Yaffe, M.B.2
López-Rodríguez, C.3
Cantley, L.C.4
Hogan, P.G.5
Rao, A.6
-
106
-
-
27844549820
-
Inhibition of the calcineurin-NFAT interaction by small organic molecules reflects binding at an allosteric site
-
Kang, S.; Li, H.; Rao, A.; Hogan, P. G. Inhibition of the calcineurin-NFAT interaction by small organic molecules reflects binding at an allosteric site. J. Biol. Chem. 2005, 280, 37698-37706.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 37698-37706
-
-
Kang, S.1
Li, H.2
Rao, A.3
Hogan, P.G.4
|