-
1
-
-
0033304730
-
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
-
Suda, T., et al. 1999. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr. Rev. 20:345-357.
-
(1999)
Endocr. Rev.
, vol.20
, pp. 345-357
-
-
Suda, T.1
-
2
-
-
0034284970
-
Bone resorption by osteoclasts
-
Teitelbaum, S.L. 2000. Bone resorption by osteoclasts. Science. 289:1504-1508.
-
(2000)
Science
, vol.289
, pp. 1504-1508
-
-
Teitelbaum, S.L.1
-
3
-
-
0035479838
-
Genetic control of skeletal development
-
Wagner, E.F., and Karsenty, G. 2001. Genetic control of skeletal development. Curr. Opin. Genet. Dev. 11:527-532.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 527-532
-
-
Wagner, E.F.1
Karsenty, G.2
-
4
-
-
0032584208
-
Osteoclast differentiation factor is a ligand for osteoprotegerin/ osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
-
Yasuda, H., et al. 1998. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Natl. Acad. Sci. U. S. A. 95:3597-3602.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 3597-3602
-
-
Yasuda, H.1
-
5
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
-
Kong, Y.Y., et al. 1999. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature. 397:315-323.
-
(1999)
Nature
, vol.397
, pp. 315-323
-
-
Kong, Y.Y.1
-
6
-
-
12944262423
-
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
-
Li, J., et al. 2000. RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc. Natl. Acad. Sci. U. S. A. 97:1566-1571.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 1566-1571
-
-
Li, J.1
-
7
-
-
0033561039
-
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
-
Lomaga, M.A., et al. 1999. TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev. 13:1015-1024.
-
(1999)
Genes Dev.
, vol.13
, pp. 1015-1024
-
-
Lomaga, M.A.1
-
8
-
-
6544270833
-
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice
-
Naito, A., et al. 1999. Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice. Genes Cells. 4:353-362.
-
(1999)
Genes Cells
, vol.4
, pp. 353-362
-
-
Naito, A.1
-
9
-
-
15444357762
-
Requirement for NF-kappaB in osteoclast and B-cell development
-
Franzoso, G., et al. 1997. Requirement for NF-kappaB in osteoclast and B-cell development. Genes Dev. 11:3482-3496.
-
(1997)
Genes Dev.
, vol.11
, pp. 3482-3496
-
-
Franzoso, G.1
-
10
-
-
0034613188
-
Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL)
-
Matsumoto, M.; Sudo, T., Saito, T., Osada, H., and Tsujimoto, M. 2000. Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL). J. Biol. Chem. 275:31155-31161.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31155-31161
-
-
Matsumoto, M.1
Sudo, T.2
Saito, T.3
Osada, H.4
Tsujimoto, M.5
-
11
-
-
0035868884
-
Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis
-
Kobayashi, N., et al. 2001. Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. EMBO J. 20:1271-1280.
-
(2001)
EMBO J.
, vol.20
, pp. 1271-1280
-
-
Kobayashi, N.1
-
12
-
-
0028173214
-
c-Fos: A key regulator of osteoclast-macrophage lineage determination and bone remodeling
-
Grigoriadis, A.E., et al. 1994. c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science. 266:443-448.
-
(1994)
Science
, vol.266
, pp. 443-448
-
-
Grigoriadis, A.E.1
-
13
-
-
0027219303
-
A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth inculture
-
Johnson, R.S., van Lingen, B., Papaioannou, V.E., and Spiegelman, B.M. 1993. A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth inculture. Genes Dev. 7:1309-1317.
-
(1993)
Genes Dev.
, vol.7
, pp. 1309-1317
-
-
Johnson, R.S.1
Van Lingen, B.2
Papaioannou, V.E.3
Spiegelman, B.M.4
-
14
-
-
0029914612
-
AP-1/jun is required for early Xenopus development and mediates mesoderm induction by fibroblast growth factor but not by activin
-
Dong, Z., et al. 1996. AP-1/jun is required for early Xenopus development and mediates mesoderm induction by fibroblast growth factor but not by activin. J. Biol. Chem. 271:9942-9946.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9942-9946
-
-
Dong, Z.1
-
15
-
-
0031016440
-
Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis
-
Lenczowski, J.M., et al. 1997. Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis. Mol. Cell. Biol. 17:170-181.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 170-181
-
-
Lenczowski, J.M.1
-
16
-
-
0028915294
-
Characterization of the mouse tartrate-resistant acid phosphatase (TRAP) gene promoter
-
Reddy, S.V., et al. 1995. Characterization of the mouse tartrate-resistant acid phosphatase (TRAP) gene promoter. J. Bone Miner. Res. 10:601-606.
-
(1995)
J. Bone Miner. Res.
, vol.10
, pp. 601-606
-
-
Reddy, S.V.1
-
18
-
-
0034677177
-
Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction
-
Kobayashi, K., et al. 2000. Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J. Exp. Med. 191:275-286.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 275-286
-
-
Kobayashi, K.1
-
19
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
-
Bennett, B.L., et al. 2001. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc. Natl. Acad. Sci. U. S. A. 98:13681-13686.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 13681-13686
-
-
Bennett, B.L.1
-
20
-
-
0035971436
-
Partners in transcription: NFAT and AP-1
-
Macian, F., Lopez-Rodriguez, C., and Rao, A. 2001. Partners in transcription: NFAT and AP-1. Oncogene. 20:2476-2489.
-
(2001)
Oncogene
, vol.20
, pp. 2476-2489
-
-
Macian, F.1
Lopez-Rodriguez, C.2
Rao, A.3
-
21
-
-
0036234543
-
NFAT signaling: Choreographing the social lives of cells
-
Crabtree, G.R., and Olson, E.N. 2002. NFAT signaling: choreographing the social lives of cells [review]. Cell. 109(Suppl.):S67-S79.
-
(2002)
Cell.
, vol.109
, Issue.SUPPL.
-
-
Crabtree, G.R.1
Olson, E.N.2
-
22
-
-
0141483523
-
Transcriptional regulation by calcium, calcineurin, and NFAT
-
Hogan, P.G., Chen, L., Nardone, J., and Rao, A. 2003. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev. 17:2205-2232.
-
(2003)
Genes Dev.
, vol.17
, pp. 2205-2232
-
-
Hogan, P.G.1
Chen, L.2
Nardone, J.3
Rao, A.4
-
23
-
-
0032849010
-
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A
-
Aramburu, J., et al. 1999. Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A. Science. 285:2129-2133.
-
(1999)
Science
, vol.285
, pp. 2129-2133
-
-
Aramburu, J.1
-
24
-
-
0037174944
-
Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator
-
Ishida, N., et al. 2002. Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator. J. Biol. Chem. 277:41147-41156.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41147-41156
-
-
Ishida, N.1
-
25
-
-
18744366041
-
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
-
Takayanagi, H., et al. 2002. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev. Cell. 3:889-901.
-
(2002)
Dev. Cell.
, vol.3
, pp. 889-901
-
-
Takayanagi, H.1
-
26
-
-
0032831780
-
The JNKK2-JNK1 fusion protein acts as a constitutively active c-Jun kinase that stimulates c-Jun transcription activity
-
Zheng, C., Xiang, J., Hunter, T., and Lin, A. 1999. The JNKK2-JNK1 fusion protein acts as a constitutively active c-Jun kinase that stimulates c-Jun transcription activity. J. Biol. Chem. 274:28966-28971.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28966-28971
-
-
Zheng, C.1
Xiang, J.2
Hunter, T.3
Lin, A.4
-
27
-
-
0037155830
-
Regulation of the murine Nfatc1 gene by NFATc2
-
Zhou, B., et al. 2002. Regulation of the murine Nfatc1 gene by NFATc2. J Biol. Chem. 277:10704-10711.
-
(2002)
J Biol. Chem.
, vol.277
, pp. 10704-10711
-
-
Zhou, B.1
-
28
-
-
0033698581
-
Manipulating immune responses with immunosuppressive agents that target NFAT
-
Kiani, A., Rao, A., and Aramburu, J. 2000. Manipulating immune responses with immunosuppressive agents that target NFAT. Immunity. 12:359-372.
-
(2000)
Immunity
, vol.12
, pp. 359-372
-
-
Kiani, A.1
Rao, A.2
Aramburu, J.3
-
30
-
-
11144354330
-
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis
-
Koga, T., et al. 2004. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature. 428:758-763.
-
(2004)
Nature
, vol.428
, pp. 758-763
-
-
Koga, T.1
-
31
-
-
0032532753
-
Life without white fat: A transgenic mouse
-
Moitra, J., et al. 1998. Life without white fat: a transgenic mouse. Genes Dev. 12:3168-3181.
-
(1998)
Genes Dev.
, vol.12
, pp. 3168-3181
-
-
Moitra, J.1
-
32
-
-
0031297248
-
δ-opioid receptors expressed by Jurkat T cells enhance IL-2 secretion by increasing AP-1 complexes and activity of the NF-AT/AP-1-binding promoter element
-
Hedin, K.E., et al. 1997. δ-opioid receptors expressed by Jurkat T cells enhance IL-2 secretion by increasing AP-1 complexes and activity of the NF-AT/AP-1-binding promoter element. J. Immunol. 159:5431-5440.
-
(1997)
J. Immunol.
, vol.159
, pp. 5431-5440
-
-
Hedin, K.E.1
-
33
-
-
0037077135
-
Transcriptional mechanisms underlying lymphocyte tolerance
-
Macian, F., et al. 2002. Transcriptional mechanisms underlying lymphocyte tolerance. Cell. 109:719-731.
-
(2002)
Cell.
, vol.109
, pp. 719-731
-
-
Macian, F.1
-
34
-
-
0032694245
-
JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a scaffold factor in the JNK signaling pathway
-
Ito, M., et al. 1999. JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a scaffold factor in the JNK signaling pathway. Mol. Cell. Biol. 19:7539-7548.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7539-7548
-
-
Ito, M.1
-
35
-
-
0035858884
-
Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation
-
Monzen, K., et al. 2001. Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation. J. Cell Biol. 153:687-698.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 687-698
-
-
Monzen, K.1
-
36
-
-
0031939744
-
Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12
-
Nishimura, R., et al. 1998. Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12. J. Biol. Chem. 273:1872-1879.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1872-1879
-
-
Nishimura, R.1
-
37
-
-
0036021077
-
Core-binding factor α1-(Cbfa1) induces osteoblastic differentiation of C2C12 cells without interactions with Smad1 and Smad5
-
Nishimura, R., Hata, K., Harris, S.E., Ikeda, F., and Yoneda, T. 2002. Core-binding factor α1-(Cbfa1) induces osteoblastic differentiation of C2C12 cells without interactions with Smad1 and Smad5. Bone. 31:303-312.
-
(2002)
Bone
, vol.31
, pp. 303-312
-
-
Nishimura, R.1
Hata, K.2
Harris, S.E.3
Ikeda, F.4
Yoneda, T.5
-
38
-
-
0037323398
-
Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor γ during bone morphogenetic protein 2-induced adipogenesis
-
Hata, K., et al. 2003. Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor γ during bone morphogenetic protein 2-induced adipogenesis. Mol. Biol. Cell. 14:545-555.
-
(2003)
Mol. Biol. Cell.
, vol.14
, pp. 545-555
-
-
Hata, K.1
-
39
-
-
0030070724
-
Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome
-
Miyake, S., et al. 1996. Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Natl. Acad. Sci. U. S. A. 93:1320-1324.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 1320-1324
-
-
Miyake, S.1
-
40
-
-
0034046944
-
PlatE: An efficient and stable system for transient packaging of retroviruses
-
Morita, S., Kojima, T., and Kitamura, T. 2000. PlatE: an efficient and stable system for transient packaging of retroviruses. Gene Ther. 7:1063-1066.
-
(2000)
Gene Ther.
, vol.7
, pp. 1063-1066
-
-
Morita, S.1
Kojima, T.2
Kitamura, T.3
-
41
-
-
0141953270
-
A JNK-dependent pathway is required for TNFα-induced apoptosis
-
Deng, Y., Ren, X., Yang, L., Lin, Y., and Wu, X. 2003. A JNK-dependent pathway is required for TNFα-induced apoptosis. Cell. 115:61-70.
-
(2003)
Cell.
, vol.115
, pp. 61-70
-
-
Deng, Y.1
Ren, X.2
Yang, L.3
Lin, Y.4
Wu, X.5
|