Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver

Journal of Biological Chemistry

Volumn 282, Issue 13, 2007, Pages 9768-9776

  Nakamura, Kouichi ^a   Moore, Rick ^a   Negishi, Masahiko ^a   Sueyoshi, Tatsuya ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATIC TRIGLYCERIDES; LIPID METABOLISM; PREGNANE X RECEPTOR (PXR);

ENZYME ACTIVITY; INSULIN; LIPIDS; METABOLISM; RATS; RNA;

DRUG PRODUCTS;

16ALPHA CYANOPREGNENOLONE; ACYL COENZYME A DESATURASE; CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE 1A; CELL NUCLEUS RECEPTOR; GLUTATHIONE TRANSFERASE; HEPATOCYTE NUCLEAR FACTOR 3BETA; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE 2; MESSENGER RNA; MITOCHONDRIAL ENZYME; PREGNANE X RECEPTOR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; FOXA2 PROTEIN, RAT; STEROID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVATION; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYME REPRESSION; FATTY ACID OXIDATION; GENE ACTIVATION; GENE REPRESSION; GENETIC TRANSCRIPTION; INSULIN RESPONSE; KETOGENESIS; LIPID METABOLISM; LIPOGENESIS; LIVER; LOW FAT DIET; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; UPREGULATION; ANIMAL; DIET RESTRICTION; DRUG EFFECT; GENETICS; HUMAN; INSTITUTE FOR CANCER RESEARCH MOUSE; MALE; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

MUS;

ANIMALS; CELL LINE, TUMOR; FASTING; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HUMANS; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; PREGNENOLONE CARBONITRILE; RATS; RECEPTOR CROSS-TALK; RECEPTORS, STEROID;

EID: 34248202757     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M610072200     Document Type: Article

References (47)

1. Honkakoski, P., Zelko, I., Sueyoshi, T., and Negishi, M. (1998) Mol. Cell. Biol. 18, 5652-5658
2. Sueyoshi, T., Kawamoto, T., Zelko, I., Honkakoski, P., and Negishi, M. (1999) J. Biol. Chem. 274, 6043-6046
3. Kliewer, S. A., Moore, J. T., Wade, L., Staudinger, J. L., Watson, M. A., Jones, S. A., McKee, D. D., Oliver, B. B., Willson, T. M., Zetterstrom, R. H., Perlmann, T., and Lehmann, J. M. (1998) Cell 92, 73-82
4. Honkakoski, P., Sueyoshi, T., and Negishi, M. (2003) Ann. Med. 35, 172-182
5. Willson, T. M., and Kliewer, S. A. (2002) Nat. Rev. Drug Discov. 1, 259-266
6. Yamamoto, Y., Kawamoto, T., and Negishi, M. (2003) Arch. Biochem. Biophys. 409, 207-211
7. Sonoda, J., Rosenfeld, J. M., Xu, L., Evans, R. M., and Xie, W. (2003) Curr. Drug Metab. 4, 59-72
8. Wei, P., Zhang, J., Egan-Hafley, M., Liang, S., and Moore, D. D. (2000) Nature 407, 920-923
9. Sueyoshi, T., and Negishi, M. (2001) Annu. Rev. Pharmacol. Toxicol. 41, 123-143
10. Goodwin, B., Redinbo, M. R., and Kliewer, S. A. (2002) Annu. Rev. Pharmacol. Toxicol. 42, 1-23
11. Sugatani, J., Kojima, H., Ueda, A., Kakizaki, S., Yoshinari, K., Gong, Q. H., Owens, I. S., Negishi, M., and Sueyoshi, T. (2001) Hepatology 33, 1232-1238
12. Sugatani, J., Sueyoshi, T., Negishi, M., and Miwa, M. (2005) Methods Enzymol. 400, 92-104
13. Xie, W., Yeuh, M. F., Radominska-Pandya, A., Saini, S. P., Negishi, Y., Bottroff, B. S., Cabrera, G. Y., Tukey, R. H., and Evans, R. M. (2003) Proc. Natl. Acad. Sci. U. S. A 100, 4150-4155
14. Runge-Morris, M., and Kocarek, T. A. (2005) Curr. Drug Metab. 6, 299-307
15. Klaassen, C. D., and Slitt, A. L. (2005) Curr. Drug Metab. 6, 309-328
16. Ueda, A., Hamadeh, H. K., Webb, H. K., Yamamoto, Y., Sueyoshi, T., Afshari, C. A., Lehmann, J. M., and Negishi, M. (2002) Mol. Pharmacol. 61, 1-6
17. Kodama, S., Koike, C., Negishi, M., and Yamamoto, Y. (2004) Mol. Cell. Biol. 24, 7931-7940
18. Rosenfeld, J. M., Vargas, R., Jr., Xie, W., and Evans, R. M. (2003) Mol. Endocrinol. 17, 1268-1282
19. Bartlett, K., and Eaton, S. (2004) Eur. J. Biochem. 271, 462-469
20. Laffel, L. (1999) Diabetes Metab. Res. Rev. 15, 412-426
21. Fukao, T., Lopaschuk, G. D., and Mitchell, G. A. (2004) Prostaglandins Leukot. Essent. Fatty Acids 70, 243-251
22. Eaton, S., Bartlett, K., and Pourfarzam, M. (1996) Biochem. J. 320, 345-357
23. Hegardt, F. G. (1999) Biochem. J. 338, 569-582
24. Louet, J. F., Le May, C., Pegorier, J. P., Decaux, J. F., and Girard, J. (2001) Biochem. Soc. Trans. 29, 310-316
25. Wolfrum, C., Asilmaz, E., Luca, E., Friedman, J. M., and Stoffel, M. (2004) Nature 432, 1027-1032
26. Wolfrum, C., Besser, D., Luca, E., and Stoffel, M. (2003) Proc. Natl. Acad. Sci. U. S. A 100, 11624-11629
27. Wang, H., and Wollheim, C. B. (2005) Trends Mol. Med. 11, 262-265
28. Kiyosawa, N., Tanaka, K., Hirao, J., Ito, K., Niino, N., Sakuma, K., Kanbori, M., Yamoto, T., Manabe, S., and Matsunuma, N. (2004) Arch. Toxicol. 78, 435-442
29. Rausa, F. M., Tan, Y., and Costa, R. H. (2003) Mol. Cell. Biol. 23, 437-449
30. Pani, L., Overdier, D. G., Porcella, A., Qian, X., Lai, E., and Costa, R. H. (1992) Mol. Cell. Biol. 12, 3723-3732
31. Squires, E. J., Sueyoshi, T., and Negishi, M. (2004) J. Biol. Chem. 279, 49307-49314
32. Kobayashi, K., Sueyoshi, T., Inoue, K., Moore, R., and Negishi, M. (2003) Mol. Pharmacol. 64, 1069-1075
33. Allander, S. V., Durham, S. K., Scheimann, A. O., Wasserman, R. M., Suwanichkul, A., and Powell, D. R. (1997) Endocrinology 138, 4291-4300
34. Kakizaki, S., Karami, S., and Negishi, M. (2002) Drug Metab. Dispos. 30, 208-211
35. Ishii, S., Iizuka, K., Miller, B. C., and Uyeda, K. (2004) Proc. Natl. Acad. Sci. U. S. A 101, 15597-15602
36. Gorski, K., Carneiro, M., and Schibler, U. (1986) Cell 47, 767-776
37. Bligh, E. G., and Dyer, W. J. (1959) Can. J. Biochem. Physiol. 37, 911-917
38. Waters, K. M., and Ntambi, J. M. (1994) J. Biol. Chem. 269, 27773-27777
39. Mounier, C., and Posner, B. I. (2006) Can. J. Physiol. Pharmacol. 84, 713-724
40. Zhou, J., Zhai, Y., Mu, Y., Gong, H., Uppal, H., Toma, D., Ren, S., Evans, R. M., and Xie, W. (2006) J. Biol. Chem. 281, 15013-15020
41. Listenberger, L. L., Han, X., Lewis, S. E., Cases, S., Farese, R. V., Jr., Ory, D. S., and Schaffer, J. E. (2003) Proc. Natl. Acad. Sci. U. S. A 100, 3077-3082
42. Miyazaki, M., Kim, Y. C., Gray-Keller, M. P., Attie, A. D., and Ntambi, J. M. (2000) J. Biol. Chem. 275, 30132-30138
43. Tabor, D. E., Kim, J. B., Spiegelman, B. M., and Edwards, P. A. (1999) J. Biol. Chem. 274, 20603-20610
44. Grefhorst, A., Hoekstra, J., Derks, T. G., Ouwens, D. M., Baller, J. F., Havinga, R., Havekes, L. M., Romijn, J. A., and Kuipers, F. (2005) Am. J. Physiol. 289, G592-G598
45. Nyman, L. R., Cox, K. B., Hoppel, C. L., Kerner, J., Barnoski, B. L., Hamm, D. A., Tian, L., Schoeb, T. R., and Wood, P. A. (2005) Mol. Genet. Metab. 86, 179-187
46. Olpin, S. E. (2004) Prostaglandins Leukot. Essent. Fatty Acids 70, 293-308
47. Rinaldo, P., Matern, D., and Bennett, M. J. (2002) Annu. Rev. Physiol. 64, 477-502