-
1
-
-
2342466734
-
Global prevalence of diabetes: Estimates for the year 2000 projections for 2030
-
S. Wild Global prevalence of diabetes: estimates for the year 2000 projections for 2030 Diabetes Care 27 2004 1047 1053
-
(2004)
Diabetes Care
, vol.27
, pp. 1047-1053
-
-
Wild, S.1
-
2
-
-
11144244418
-
Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes
-
C. Wolfrum Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes Nature 432 2004 1027 1032
-
(2004)
Nature
, vol.432
, pp. 1027-1032
-
-
Wolfrum, C.1
-
3
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1α interaction
-
P. Puigserver Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1α interaction Nature 423 2003 550 555
-
(2003)
Nature
, vol.423
, pp. 550-555
-
-
Puigserver, P.1
-
4
-
-
0036950665
-
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth
-
T. Kitamura The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth J. Clin. Invest. 110 2002 1839 1847
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1839-1847
-
-
Kitamura, T.1
-
5
-
-
0037237279
-
The forkhead transcription factor Foxo1 regulates adipocyte differentiation
-
J. Nakae The forkhead transcription factor Foxo1 regulates adipocyte differentiation Dev. Cell 4 2003 119 129
-
(2003)
Dev. Cell
, vol.4
, pp. 119-129
-
-
Nakae, J.1
-
6
-
-
0842263985
-
Role of peroxisome proliferator-activated receptor-γ in the glucose-sensing apparatus of liver and β-cells
-
H.I. Kim, and Y.H. Ahn Role of peroxisome proliferator-activated receptor-γ in the glucose-sensing apparatus of liver and β-cells Diabetes 53 Suppl. 1 2004 S60 S65
-
(2004)
Diabetes
, vol.53
, Issue.1 SUPPL.
-
-
Kim, H.I.1
Ahn, Y.H.2
-
7
-
-
0030695445
-
The maturity-onset diabetes of the young (MODY1) transcription factor HNF4α regulates expression of genes required for glucose transport and metabolism
-
M. Stoffel, and S.A. Duncan The maturity-onset diabetes of the young (MODY1) transcription factor HNF4α regulates expression of genes required for glucose transport and metabolism Proc. Natl. Acad. Sci. U. S. A. 94 1997 13209 13214
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13209-13214
-
-
Stoffel, M.1
Duncan, S.A.2
-
8
-
-
19944432614
-
Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity
-
Y. Ishigaki Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity Diabetes 54 2005 322 332
-
(2005)
Diabetes
, vol.54
, pp. 322-332
-
-
Ishigaki, Y.1
-
9
-
-
2342652187
-
Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver
-
P. Dobrzyn Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver Proc. Natl. Acad. Sci. U. S. A. 101 2004 6409 6414
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 6409-6414
-
-
Dobrzyn, P.1
-
10
-
-
0028025566
-
The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo
-
D.C. Weinstein The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo Cell 78 1994 575 588
-
(1994)
Cell
, vol.78
, pp. 575-588
-
-
Weinstein, D.C.1
-
11
-
-
0033921664
-
Hepatocyte nuclear factor 3β (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte
-
N. Sund Hepatocyte nuclear factor 3β (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte Mol. Cell. Biol. 20 2000 5175 5183
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5175-5183
-
-
Sund, N.1
-
12
-
-
0037566080
-
Elevated hepatocyte levels of the forkhead box A2 (HNF-3β) transcription factor cause postnatal steatosis and mitochondrial damage
-
D.E. Hughes Elevated hepatocyte levels of the forkhead box A2 (HNF-3β) transcription factor cause postnatal steatosis and mitochondrial damage Hepatology 37 2003 1414 1424
-
(2003)
Hepatology
, vol.37
, pp. 1414-1424
-
-
Hughes, D.E.1
-
13
-
-
0141705364
-
Insulin regulates the activity of forkhead transcription factor Hnf-3β/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization
-
C. Wolfrum Insulin regulates the activity of forkhead transcription factor Hnf-3β/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization Proc. Natl. Acad. Sci. U. S. A. 100 2003 11624 11629
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 11624-11629
-
-
Wolfrum, C.1
-
14
-
-
85047692037
-
Role of Foxa-2 in adipocyte metabolism and differentiation
-
C. Wolfrum Role of Foxa-2 in adipocyte metabolism and differentiation J. Clin. Invest. 112 2003 345 356
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 345-356
-
-
Wolfrum, C.1
-
15
-
-
12944336527
-
Foxa2 is required for the differentiation of pancreatic α-cells
-
C.S. Lee Foxa2 is required for the differentiation of pancreatic α-cells Dev. Biol. 278 2005 484 495
-
(2005)
Dev. Biol.
, vol.278
, pp. 484-495
-
-
Lee, C.S.1
-
16
-
-
0033557490
-
Inactivation of the winged helix transcription factor HNF3α affects glucose homeostasis and islet glucagon gene expression in vivo
-
K. Kaestner Inactivation of the winged helix transcription factor HNF3α affects glucose homeostasis and islet glucagon gene expression in vivo Genes Dev. 13 1999 495 504
-
(1999)
Genes Dev.
, vol.13
, pp. 495-504
-
-
Kaestner, K.1
-
17
-
-
0033621155
-
Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3α-deficient mice
-
D. Shih Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3α-deficient mice Proc. Natl. Acad. Sci. U. S. A. 96 1999 10152 10157
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 10152-10157
-
-
Shih, D.1
-
18
-
-
0035900778
-
Foxa3 (hepatocyte nuclear factor 3γ) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast
-
W. Shen Foxa3 (hepatocyte nuclear factor 3γ) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast J. Biol. Chem. 276 2001 42812 42817
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42812-42817
-
-
Shen, W.1
-
19
-
-
0031834339
-
Targeted disruption of the gene encoding hepatocyte nuclear factor 3γ results in reduced transcription of hepatocyte-specific genes
-
K.H. Kaestner Targeted disruption of the gene encoding hepatocyte nuclear factor 3γ results in reduced transcription of hepatocyte-specific genes Mol. Cell. Biol. 18 1998 4245 4251
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4245-4251
-
-
Kaestner, K.H.1
-
20
-
-
0038003956
-
Decisions on life and death: FOXO forkhead transcription factors are in command when PKB/Akt is off duty
-
B.M. Burgering, and R.H. Medema Decisions on life and death: FOXO forkhead transcription factors are in command when PKB/Akt is off duty J. Leukoc. Biol. 73 2003 689 701
-
(2003)
J. Leukoc. Biol.
, vol.73
, pp. 689-701
-
-
Burgering, B.M.1
Medema, R.H.2
-
21
-
-
0036787607
-
Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
-
J. Nakae Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1 Nat. Genet. 32 2002 245 253
-
(2002)
Nat. Genet.
, vol.32
, pp. 245-253
-
-
Nakae, J.1
-
22
-
-
0036323652
-
Foxa2 controls Pdx1 gene expression in pancreatic β-cells in vivo
-
C.S. Lee Foxa2 controls Pdx1 gene expression in pancreatic β-cells in vivo Diabetes 51 2002 2546 2551
-
(2002)
Diabetes
, vol.51
, pp. 2546-2551
-
-
Lee, C.S.1
-
23
-
-
0033811031
-
Identification of missense mutations in the hepatocyte nuclear factor-3β gene in Japanese subjects with late-onset Type II diabetes mellitus
-
Q. Zhu Identification of missense mutations in the hepatocyte nuclear factor-3β gene in Japanese subjects with late-onset Type II diabetes mellitus Diabetologia 43 2000 1197 1200
-
(2000)
Diabetologia
, vol.43
, pp. 1197-1200
-
-
Zhu, Q.1
-
24
-
-
85047691646
-
Foxa2 regulates multiple pathways of insulin secretion
-
K.A. Lantz Foxa2 regulates multiple pathways of insulin secretion J. Clin. Invest. 114 2004 512 520
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 512-520
-
-
Lantz, K.A.1
-
26
-
-
0034902277
-
Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of β-oxidation in insulin secretion
-
P.T. Clayton Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of β-oxidation in insulin secretion J. Clin. Invest. 108 2001 457 465
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 457-465
-
-
Clayton, P.T.1
-
27
-
-
0037123437
-
Foxa2 (HNF3β) controls multiple genes implicated in metabolism secretion coupling of glucose-induced insulin release
-
H. Wang Foxa2 (HNF3β) controls multiple genes implicated in metabolism secretion coupling of glucose-induced insulin release J. Biol. Chem. 277 2002 17564 17570
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 17564-17570
-
-
Wang, H.1
|