-
1
-
-
15844408798
-
APP-BPI, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein
-
Chow N, Korenberg JR, Chen XN, Neve RL: APP-BPI, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein. J Biol Chem 1996, 271(19):11339-11346.
-
(1996)
J Biol Chem
, vol.271
, Issue.19
, pp. 11339-11346
-
-
Chow, N.1
Korenberg, J.R.2
Chen, X.N.3
Neve, R.L.4
-
2
-
-
0034708641
-
The amyloid precursor protein-binding protein APP-BPI drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons
-
Chen Y, McPhie DL, Hirschberg J, Neve RL: The amyloid precursor protein-binding protein APP-BPI drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons. J Biol Chem 2000, 275(12):8929-8935.
-
(2000)
J Biol Chem
, vol.275
, Issue.12
, pp. 8929-8935
-
-
Chen, Y.1
McPhie, D.L.2
Hirschberg, J.3
Neve, R.L.4
-
3
-
-
0032146145
-
A new NEDD8-ligating system for cullin-4A
-
Osaka F, Kawasaki H, Aida N, Saeki M, Chiba T, Kawashima S, Tanaka K, Kato S: A new NEDD8-ligating system for cullin-4A. Genes Dev 1998, 12(15):2263-2268.
-
(1998)
Genes Dev
, vol.12
, Issue.15
, pp. 2263-2268
-
-
Osaka, F.1
Kawasaki, H.2
Aida, N.3
Saeki, M.4
Chiba, T.5
Kawashima, S.6
Tanaka, K.7
Kato, S.8
-
4
-
-
0033581899
-
Covalent modification of all members of human cullin family proteins by NEDD8
-
Hori T, Osaka F, Chiba T, Miyamoto C, Okabayashi K, Shimbara N, Kato S, Tanaka K: Covalent modification of all members of human cullin family proteins by NEDD8. Oncogene 1999, 18(48):6829-6834.
-
(1999)
Oncogene
, vol.18
, Issue.48
, pp. 6829-6834
-
-
Hori, T.1
Osaka, F.2
Chiba, T.3
Miyamoto, C.4
Okabayashi, K.5
Shimbara, N.6
Kato, S.7
Tanaka, K.8
-
5
-
-
27144525246
-
Neddylation and deneddylation regulate Cull and Cul3 protein accumulation
-
Wu JT, Lin HC, Hu YC, Chien CT: Neddylation and deneddylation regulate Cull and Cul3 protein accumulation. Nat Cell Biol 2005.
-
(2005)
Nat Cell Biol
-
-
Wu, J.T.1
Lin, H.C.2
Hu, Y.C.3
Chien, C.T.4
-
6
-
-
0026460979
-
The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1
-
Handeli S, Weintraub H: The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1. Cell 1992, 71(4):599-611.
-
(1992)
Cell
, vol.71
, Issue.4
, pp. 599-611
-
-
Handeli, S.1
Weintraub, H.2
-
7
-
-
0035969236
-
The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice
-
Tateishi K, Omata M, Tanaka K, Chiba T: The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice. J Cell Biol 2001, 155(4):571-579.
-
(2001)
J Cell Biol
, vol.155
, Issue.4
, pp. 571-579
-
-
Tateishi, K.1
Omata, M.2
Tanaka, K.3
Chiba, T.4
-
8
-
-
0142059983
-
APP-BPI mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain
-
Chen Y, Liu W, McPhie DL, Hassinger L, Neve RL: APP-BPI mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain. J Cell Biol 2003, 163(1):27-33.
-
(2003)
J Cell Biol
, vol.163
, Issue.1
, pp. 27-33
-
-
Chen, Y.1
Liu, W.2
McPhie, D.L.3
Hassinger, L.4
Neve, R.L.5
-
9
-
-
34247875121
-
Drosophila homolog of APP-BPI (dAPP-BPI) interacts antagonistically with APPL during Drosophila development
-
Kim HJ, Kim SH, Shim SO, Park E, Kim C, Kim K, Tanouye MA, Yim J: Drosophila homolog of APP-BPI (dAPP-BPI) interacts antagonistically with APPL during Drosophila development. Cell Death Differ 2006.
-
(2006)
Cell Death Differ
-
-
Kim, H.J.1
Kim, S.H.2
Shim, S.O.3
Park, E.4
Kim, C.5
Kim, K.6
Tanouye, M.A.7
Yim, J.8
-
10
-
-
0033535553
-
Two transmembrane aspartates in presenilin-I required for presenilin endoproteolysis and gamma-secretase activity
-
Wolfe MS, Xia W, Ostaszewski BL, Diehl TS, Kimberly WT, Selkoe DJ: Two transmembrane aspartates in presenilin-I required for presenilin endoproteolysis and gamma-secretase activity. Nature 1999, 398(6727):513-517.
-
(1999)
Nature
, vol.398
, Issue.6727
, pp. 513-517
-
-
Wolfe, M.S.1
Xia, W.2
Ostaszewski, B.L.3
Diehl, T.S.4
Kimberly, W.T.5
Selkoe, D.J.6
-
11
-
-
17944376442
-
APP processing and synaptic plasticity in presenilin-I conditional knockout mice
-
Yu H, Saura CA, Choi SY, Sun LD, Yang X, Handler M, Kawarabayashi T, Younkin L, Fedeles B, Wilson MA, et al.: APP processing and synaptic plasticity in presenilin-I conditional knockout mice. Neuron 2001, 31(5):713-726.
-
(2001)
Neuron
, vol.31
, Issue.5
, pp. 713-726
-
-
Yu, H.1
Saura, C.A.2
Choi, S.Y.3
Sun, L.D.4
Yang, X.5
Handler, M.6
Kawarabayashi, T.7
Younkin, L.8
Fedeles, B.9
Wilson, M.A.10
-
12
-
-
0033775709
-
Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells
-
Herreman A, Serneels L, Annaert W, Collen D, Schoonjans L, De Strooper B: Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells. Nat Cell Biol 2000, 2(7):461-462.
-
(2000)
Nat Cell Biol
, vol.2
, Issue.7
, pp. 461-462
-
-
Herreman, A.1
Serneels, L.2
Annaert, W.3
Collen, D.4
Schoonjans, L.5
De Strooper, B.6
-
13
-
-
0035900774
-
Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PSI knockout cells
-
Wiltfang J, Esselmann H, Cupers P, Neumann M, Kretzschmar H, Beyermann M, Schleuder D, Jahn H, Ruther E, Kornhuber J, et al.: Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PSI knockout cells. J Biol Chem 2001, 276(46):42645-42657.
-
(2001)
J Biol Chem
, vol.276
, Issue.46
, pp. 42645-42657
-
-
Wiltfang, J.1
Esselmann, H.2
Cupers, P.3
Neumann, M.4
Kretzschmar, H.5
Beyermann, M.6
Schleuder, D.7
Jahn, H.8
Ruther, E.9
Kornhuber, J.10
-
14
-
-
0035845481
-
Loss of presenilin I is associated with enhanced beta-catenin signaling and skin tumorigenesis
-
Xia X, Qian S, Soriano S, Wu Y, Fletcher AM, Wang XJ, Koo EH, Wu X, Zheng H: Loss of presenilin I is associated with enhanced beta-catenin signaling and skin tumorigenesis. Proc NatlAcad Sci USA 2001, 98(19):10863-10868.
-
(2001)
Proc NatlAcad Sci USA
, vol.98
, Issue.19
, pp. 10863-10868
-
-
Xia, X.1
Qian, S.2
Soriano, S.3
Wu, Y.4
Fletcher, A.M.5
Wang, X.J.6
Koo, E.H.7
Wu, X.8
Zheng, H.9
-
15
-
-
0037421206
-
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts
-
Ehehalt R, Keller P, Haass C, Thiele C, Simons K: Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts. J Cell Biol 2003, 160(1):113-123.
-
(2003)
J Cell Biol
, vol.160
, Issue.1
, pp. 113-123
-
-
Ehehalt, R.1
Keller, P.2
Haass, C.3
Thiele, C.4
Simons, K.5
-
16
-
-
7244258941
-
Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes
-
Vetrivel KS, Cheng H, Lin W, Sakurai T, Li T, Nukina N, Wong PC, Xu H, Thinakaran G: Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes, J Biol Chem 2004, 279(43):44945-44954.
-
(2004)
J Biol Chem
, vol.279
, Issue.43
, pp. 44945-44954
-
-
Vetrivel, K.S.1
Cheng, H.2
Lin, W.3
Sakurai, T.4
Li, T.5
Nukina, N.6
Wong, P.C.7
Xu, H.8
Thinakaran, G.9
-
17
-
-
3342993335
-
Purification and characterization of the human gamma-secretase complex
-
Fraering PC, Ye W, Strub JM, Dolios G, LaVoie MJ, Ostaszewski BL, van Dorsselaer A, Wang R, Selkoe DJ, Wolfe MS: Purification and characterization of the human gamma-secretase complex. Biochemistry 2004, 43(30):9774-9789.
-
(2004)
Biochemistry
, vol.43
, Issue.30
, pp. 9774-9789
-
-
Fraering, P.C.1
Ye, W.2
Strub, J.M.3
Dolios, G.4
LaVoie, M.J.5
Ostaszewski, B.L.6
van Dorsselaer, A.7
Wang, R.8
Selkoe, D.J.9
Wolfe, M.S.10
-
18
-
-
0032488995
-
The proteolytic fragments of the Alzheimer's disease-associated presenilin-I form heterodimers and occur as a 100-150-kDa molecular mass complex
-
Capell A, Grunberg J, Pesold B, Diehlmann A, Citron M, Nixon R, Beyreuther K, Selkoe DJ, Haass C: The proteolytic fragments of the Alzheimer's disease-associated presenilin-I form heterodimers and occur as a 100-150-kDa molecular mass complex. J Biol Chem 1998, 273(6):3205-3211.
-
(1998)
J Biol Chem
, vol.273
, Issue.6
, pp. 3205-3211
-
-
Capell, A.1
Grunberg, J.2
Pesold, B.3
Diehlmann, A.4
Citron, M.5
Nixon, R.6
Beyreuther, K.7
Selkoe, D.J.8
Haass, C.9
-
19
-
-
0037173071
-
The aspartate-257 of presenilin I is indispensable for mouse development and production of beta-amyloid peptides through beta-cateninindependent mechanisms
-
Xia X, Wang P, Sun X, Soriano S, Shum WK, Yamaguchi H, Trumbauer ME, Takashima A, Koo EH, Zheng H: The aspartate-257 of presenilin I is indispensable for mouse development and production of beta-amyloid peptides through beta-cateninindependent mechanisms. Proc Natl Acad Sci USA 2002, 99(13):8760-8765.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.13
, pp. 8760-8765
-
-
Xia, X.1
Wang, P.2
Sun, X.3
Soriano, S.4
Shum, W.K.5
Yamaguchi, H.6
Trumbauer, M.E.7
Takashima, A.8
Koo, E.H.9
Zheng, H.10
-
20
-
-
0035421638
-
Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability
-
De Jonghe C, Esselens C, Kumar-Singh S, Craessaerts K, Serneels S, Checler F, Annaert W, Van Broeckhoven C, De Strooper B: Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability. Hum Mol Genet 2001, 10(16):1665-1671.
-
(2001)
Hum Mol Genet
, vol.10
, Issue.16
, pp. 1665-1671
-
-
De Jonghe, C.1
Esselens, C.2
Kumar-Singh, S.3
Craessaerts, K.4
Serneels, S.5
Checler, F.6
Annaert, W.7
Van Broeckhoven, C.8
De Strooper, B.9
-
21
-
-
0036453087
-
A role for presenilin I in regulating the delivery of amyloid precursor protein to the cell surface
-
Leem JY, Saura CA, Pietrzik C, Christianson J, Wanamaker C, King LT, Veselits ML, Tomita T, Gasparini L, Iwatsubo T, et al.: A role for presenilin I in regulating the delivery of amyloid precursor protein to the cell surface. Neurobiol Dis 2002, 11(1):64-82.
-
(2002)
Neurobiol Dis
, vol.11
, Issue.1
, pp. 64-82
-
-
Leem, J.Y.1
Saura, C.A.2
Pietrzik, C.3
Christianson, J.4
Wanamaker, C.5
King, L.T.6
Veselits, M.L.7
Tomita, T.8
Gasparini, L.9
Iwatsubo, T.10
-
22
-
-
0038322593
-
gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins
-
Walsh DM, Fadeeva JV, LaVoie MJ, Paliga K, Eggert S, Kimberly WT, Wasco W, Selkoe DJ: gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins. Biochemistry 2003, 42(22):6664-6673.
-
(2003)
Biochemistry
, vol.42
, Issue.22
, pp. 6664-6673
-
-
Walsh, D.M.1
Fadeeva, J.V.2
LaVoie, M.J.3
Paliga, K.4
Eggert, S.5
Kimberly, W.T.6
Wasco, W.7
Selkoe, D.J.8
-
23
-
-
0033573477
-
C terminus of presenilin is required for overproduction of amyloidogenic Abeta42 through stabilization and endoproteolysis of presenilin
-
Tomita T, Takikawa R, Koyama A, Morohashi Y, Takasugi N, Saido TC, Maruyama K, Iwatsubo T: C terminus of presenilin is required for overproduction of amyloidogenic Abeta42 through stabilization and endoproteolysis of presenilin. J Neurosci 1999, 19(24):10627- 10634.
-
(1999)
J Neurosci
, vol.19
, Issue.24
, pp. 10627-10634
-
-
Tomita, T.1
Takikawa, R.2
Koyama, A.3
Morohashi, Y.4
Takasugi, N.5
Saido, T.C.6
Maruyama, K.7
Iwatsubo, T.8
-
24
-
-
18244389436
-
The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease
-
Gandy S: The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease. J Clin Invest 2005, 115(5):1121- 1129.
-
(2005)
J Clin Invest
, vol.115
, Issue.5
, pp. 1121-1129
-
-
Gandy, S.1
-
25
-
-
25144501662
-
Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease
-
Gouras GK, Almeida CG, Takahashi RH: Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease. Neurobiol Aging 2005.
-
(2005)
Neurobiol Aging
-
-
Gouras, G.K.1
Almeida, C.G.2
Takahashi, R.H.3
-
26
-
-
13944276825
-
Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
-
Tanzi RE, Bertram L: Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 2005, 120(4):545-555.
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
27
-
-
0028945660
-
Evidence that A beta 42 is the real culprit in Alzheimer's disease
-
Younkin SG: Evidence that A beta 42 is the real culprit in Alzheimer's disease. Ann Neurol 1995, 37(3):287-288.
-
(1995)
Ann Neurol
, vol.37
, Issue.3
, pp. 287-288
-
-
Younkin, S.G.1
-
28
-
-
0032211830
-
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease
-
Selkoe DJ: The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol 1998, 8(11):447-453.
-
(1998)
Trends Cell Biol
, vol.8
, Issue.11
, pp. 447-453
-
-
Selkoe, D.J.1
-
29
-
-
22544482926
-
Abeta42 is essential for parenchymal and vascular amyloid deposition in mice
-
McGowan E, Pickford F, Kim J, Onstead L, Eriksen J, Yu C, Skipper L, Murphy MP, Beard J, Das P, et al.: Abeta42 is essential for parenchymal and vascular amyloid deposition in mice. Neuron 2005, 47(2):191-199.
-
(2005)
Neuron
, vol.47
, Issue.2
, pp. 191-199
-
-
McGowan, E.1
Pickford, F.2
Kim, J.3
Onstead, L.4
Eriksen, J.5
Yu, C.6
Skipper, L.7
Murphy, M.P.8
Beard, J.9
Das, P.10
-
30
-
-
33645105621
-
Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms
-
Bentahir M, Nyabi O, Verhamme J, Tolia A, Horre K, Wiltfang J, Esselmann H, De Strooper B: Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms. J Neurochem 2006, 96(3):732-742.
-
(2006)
J Neurochem
, vol.96
, Issue.3
, pp. 732-742
-
-
Bentahir, M.1
Nyabi, O.2
Verhamme, J.3
Tolia, A.4
Horre, K.5
Wiltfang, J.6
Esselmann, H.7
De Strooper, B.8
-
31
-
-
33645578379
-
Deletion of presenilin I hydrophilic loop sequence leads to impaired gamma-secretase activity and exacerbated amyloid pathology
-
Deng Y, Tarassishin L, Kallhoff V, Peethumnongsin E, Wu L, Li YM, Zheng H: Deletion of presenilin I hydrophilic loop sequence leads to impaired gamma-secretase activity and exacerbated amyloid pathology. J Neurosci 2006, 26(14):3845-3854.
-
(2006)
J Neurosci
, vol.26
, Issue.14
, pp. 3845-3854
-
-
Deng, Y.1
Tarassishin, L.2
Kallhoff, V.3
Peethumnongsin, E.4
Wu, L.5
Li, Y.M.6
Zheng, H.7
-
32
-
-
33745700370
-
Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40
-
Kumar-Singh S, Theuns J, Van Broeck B, Pirici D, Vennekens K, Corsmit E, Cruts M, Dermaut B, Wang R, Van Broeckhoven C: Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40. Hum Mutat 2006, 27(7):686-695.
-
(2006)
Hum Mutat
, vol.27
, Issue.7
, pp. 686-695
-
-
Kumar-Singh, S.1
Theuns, J.2
Van Broeck, B.3
Pirici, D.4
Vennekens, K.5
Corsmit, E.6
Cruts, M.7
Dermaut, B.8
Wang, R.9
Van Broeckhoven, C.10
-
33
-
-
0038037751
-
gamma-Secretase cleavage site specificity differs for intracellular and secretory amyloid beta
-
Grimm HS, Beher D, Lichtenthaler SF, Shearman MS, Beyreuther K, Hartmann T: gamma-Secretase cleavage site specificity differs for intracellular and secretory amyloid beta, J Biol Chem 2003, 278(15):13077-13085.
-
(2003)
J Biol Chem
, vol.278
, Issue.15
, pp. 13077-13085
-
-
Grimm, H.S.1
Beher, D.2
Lichtenthaler, S.F.3
Shearman, M.S.4
Beyreuther, K.5
Hartmann, T.6
-
34
-
-
5144230066
-
Mutations in APP have independent effects on Abeta and CTFgamma generation
-
Hecimovic S, Wang J, Dolios G, Martinez M, Wang R, Goate AM: Mutations in APP have independent effects on Abeta and CTFgamma generation. Neurobiol Dis 2004, 17(2):205-218.
-
(2004)
Neurobiol Dis
, vol.17
, Issue.2
, pp. 205-218
-
-
Hecimovic, S.1
Wang, J.2
Dolios, G.3
Martinez, M.4
Wang, R.5
Goate, A.M.6
-
35
-
-
18444417998
-
aph-l and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation
-
Francis R, McGrath G, ZhangJ, Ruddy DA, Sym M, ApfeldJ, Nicoll M, Maxwell M, Hai B, Ellis MC, et al.: aph-l and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation. Dev Cell 2002, 3(1):85-97.
-
(2002)
Dev Cell
, vol.3
, Issue.1
, pp. 85-97
-
-
Francis, R.1
McGrath, G.2
Zhang, J.3
Ruddy, D.A.4
Sym, M.5
Apfeld, J.6
Nicoll, M.7
Maxwell, M.8
Hai, B.9
Ellis, M.C.10
-
36
-
-
0037154158
-
APH-I is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos
-
Goutte C, Tsunozaki M, Hale VA, Priess JR: APH-I is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos. Proc Natl Acad Sci USA 2002, 99(2):775-779.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.2
, pp. 775-779
-
-
Goutte, C.1
Tsunozaki, M.2
Hale, V.A.3
Priess, J.R.4
-
37
-
-
0034618715
-
Nicastrin modulates presenilin-mediated notch/glp-I signal transduction and betaAPP processing
-
Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song YQ, Rogaeva E, Chen F, Kawarai T, et al.: Nicastrin modulates presenilin-mediated notch/glp-I signal transduction and betaAPP processing. Nature 2000, 407(6800):48-54.
-
(2000)
Nature
, vol.407
, Issue.6800
, pp. 48-54
-
-
Yu, G.1
Nishimura, M.2
Arawaka, S.3
Levitan, D.4
Zhang, L.5
Tandon, A.6
Song, Y.Q.7
Rogaeva, E.8
Chen, F.9
Kawarai, T.10
-
38
-
-
19644389648
-
CD 147 is a regulatory subunit of the {gamma}-secretase complex in Alzheimer's disease amyloid {beta}-peptide production
-
Zhou S, Zhou H, Walian PJ, Jap BK: CD 147 is a regulatory subunit of the {gamma}-secretase complex in Alzheimer's disease amyloid {beta}-peptide production. Proc Natl Acad Sci USA 2005.
-
(2005)
Proc Natl Acad Sci USA
-
-
Zhou, S.1
Zhou, H.2
Walian, P.J.3
Jap, B.K.4
-
39
-
-
0037422599
-
Positive and negative regulation of APP amyloidogenesis by sumoylation
-
Li Y, Wang H, Wang S, Quon D, Liu YW, Cordell B: Positive and negative regulation of APP amyloidogenesis by sumoylation. Proc Natl Acad Sci USA 2003, 100(1):259-264.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.1
, pp. 259-264
-
-
Li, Y.1
Wang, H.2
Wang, S.3
Quon, D.4
Liu, Y.W.5
Cordell, B.6
-
40
-
-
0033622324
-
Intraneuronal Abeta42 accumulation in human brain
-
Gouras GK, Tsai J, Naslund J, Vincent B, Edgar M, Checler F, Greenfield JP, Haroutunian V, Buxbaum JD, Xu H, et al.: Intraneuronal Abeta42 accumulation in human brain. Am J Pathol 2000. 156(1):15-20.
-
(2000)
Am J Pathol
, vol.156
, Issue.1
, pp. 15-20
-
-
Gouras, G.K.1
Tsai, J.2
Naslund, J.3
Vincent, B.4
Edgar, M.5
Checler, F.6
Greenfield, J.P.7
Haroutunian, V.8
Buxbaum, J.D.9
Xu, H.10
-
41
-
-
0036827031
-
Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology
-
Takahashi RH, Milner TA, Li F, Nam EE, Edgar MA, Yamaguchi H, Beal MF, Xu H, Greengard P, Gouras GK: Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. Am J Pathol 2002, 161(5):1869-1879.
-
(2002)
Am J Pathol
, vol.161
, Issue.5
, pp. 1869-1879
-
-
Takahashi, R.H.1
Milner, T.A.2
Li, F.3
Nam, E.E.4
Edgar, M.A.5
Yamaguchi, H.6
Beal, M.F.7
Xu, H.8
Greengard, P.9
Gouras, G.K.10
-
42
-
-
4644319713
-
Abeta localization in abnormal endosomes: Association with earliest Abeta elevations in AD and Down syndrome
-
Cataldo AM, Petanceska S, Terio NB, Peterhoff CM, Durham R, Mercken M, Mehta PD, Buxbaum J, Haroutunian V, Nixon RA: Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome. Neurobiol Aging 2004, 25(10):1263-1272.
-
(2004)
Neurobiol Aging
, vol.25
, Issue.10
, pp. 1263-1272
-
-
Cataldo, A.M.1
Petanceska, S.2
Terio, N.B.3
Peterhoff, C.M.4
Durham, R.5
Mercken, M.6
Mehta, P.D.7
Buxbaum, J.8
Haroutunian, V.9
Nixon, R.A.10
-
43
-
-
1842732209
-
Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain
-
Takahashi RH, Almeida CG, Kearney PF, Yu F, Lin MT, Milner TA, Gouras GK: Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain. J Neurosci 2004, 24(14):3592- 3599.
-
(2004)
J Neurosci
, vol.24
, Issue.14
, pp. 3592-3599
-
-
Takahashi, R.H.1
Almeida, C.G.2
Kearney, P.F.3
Yu, F.4
Lin, M.T.5
Milner, T.A.6
Gouras, G.K.7
-
44
-
-
0034745017
-
Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome
-
Gyure KA, Durham R, Stewart WF, Smialek JE, Troncoso JC: Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome. Arch Pathol Lab Med 2001, 125(4):489-492.
-
(2001)
Arch Pathol Lab Med
, vol.125
, Issue.4
, pp. 489-492
-
-
Gyure, K.A.1
Durham, R.2
Stewart, W.F.3
Smialek, J.E.4
Troncoso, J.C.5
-
45
-
-
0037186074
-
Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome
-
Busciglio J, Pelsman A, Wong C, Pigino G, Yuan M, Mori H, Yankner BA: Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome. Neuron 2002, 33(5):677-688.
-
(2002)
Neuron
, vol.33
, Issue.5
, pp. 677-688
-
-
Busciglio, J.1
Pelsman, A.2
Wong, C.3
Pigino, G.4
Yuan, M.5
Mori, H.6
Yankner, B.A.7
-
46
-
-
0035997524
-
Intraneuronal Abeta42 accumulation in Down syndrome brain
-
Mori C, Spooner ET, Wisniewsk KE, Wisniewski TM, Yamaguch H, Saido TC, Tolan DR, Selkoe DJ, Lemere CA: Intraneuronal Abeta42 accumulation in Down syndrome brain. Amyloid 2002, 9(2):88-102.
-
(2002)
Amyloid
, vol.9
, Issue.2
, pp. 88-102
-
-
Mori, C.1
Spooner, E.T.2
Wisniewsk, K.E.3
Wisniewski, T.M.4
Yamaguch, H.5
Saido, T.C.6
Tolan, D.R.7
Selkoe, D.J.8
Lemere, C.A.9
-
47
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
-
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM: Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 2003, 39(3):409-421.
-
(2003)
Neuron
, vol.39
, Issue.3
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
LaFerla, F.M.10
-
48
-
-
12144288683
-
Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease
-
Schmitz C, Rutten BP, Pielen A, Schafer S, Wirths O, Tremp G, Czech C, Blanchard V, Multhaup G, Rezaie P, et al.: Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease. Am J Pathol 2004, 164(4):1495-1502.
-
(2004)
Am J Pathol
, vol.164
, Issue.4
, pp. 1495-1502
-
-
Schmitz, C.1
Rutten, B.P.2
Pielen, A.3
Schafer, S.4
Wirths, O.5
Tremp, G.6
Czech, C.7
Blanchard, V.8
Multhaup, G.9
Rezaie, P.10
-
49
-
-
33749521100
-
Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: Potential factors in amyloid plaque formation
-
Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L, et al.: Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation, J Neurosci 2006, 26(40):10129-10140.
-
(2006)
J Neurosci
, vol.26
, Issue.40
, pp. 10129-10140
-
-
Oakley, H.1
Cole, S.L.2
Logan, S.3
Maus, E.4
Shao, P.5
Craft, J.6
Guillozet-Bongaarts, A.7
Ohno, M.8
Disterhoft, J.9
Van Eldik, L.10
-
50
-
-
0036772311
-
Intracellular A-beta amyloid, a sign for worse things to come?
-
Echeverria V, Cuello AC: Intracellular A-beta amyloid, a sign for worse things to come? Mol Neurobiol 2002, 26(2-3):299-316.
-
(2002)
Mol Neurobiol
, vol.26
, Issue.2-3
, pp. 299-316
-
-
Echeverria, V.1
Cuello, A.C.2
-
52
-
-
0038673445
-
ASPP2 inhibits APP-BPI -mediated NEDD8 conjugation to cullin-I and decreases APP-BPI-induced cell proliferation and neuronal apoptosis
-
Chen Y, Liu W, Naumovski L, Neve RL: ASPP2 inhibits APP-BPI -mediated NEDD8 conjugation to cullin-I and decreases APP-BPI-induced cell proliferation and neuronal apoptosis. J Neurochem 2003, 85(3):801-809.
-
(2003)
J Neurochem
, vol.85
, Issue.3
, pp. 801-809
-
-
Chen, Y.1
Liu, W.2
Naumovski, L.3
Neve, R.L.4
-
53
-
-
0028232167
-
Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator
-
Pind S, Riordan JR. Williams DB: Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator, J Biol Chem 1994, 269(17):12784-12788.
-
(1994)
J Biol Chem
, vol.269
, Issue.17
, pp. 12784-12788
-
-
Pind, S.1
Riordan, J.R.2
Williams, D.B.3
-
54
-
-
0030890594
-
Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells
-
Hay JC, Chao DS, Kuo CS, Scheller RH: Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. Cell 1997, 89(1):149-158.
-
(1997)
Cell
, vol.89
, Issue.1
, pp. 149-158
-
-
Hay, J.C.1
Chao, D.S.2
Kuo, C.S.3
Scheller, R.H.4
-
55
-
-
0037440160
-
Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
-
Kawasaki H, Taira K: Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells. Nucleic Acids Res 2003, 31(2):700-707.
-
(2003)
Nucleic Acids Res
, vol.31
, Issue.2
, pp. 700-707
-
-
Kawasaki, H.1
Taira, K.2
-
56
-
-
1342306385
-
Targeting Alzheimer's disease genes with RNA interference: An efficient strategy for silencing mutant alleles
-
Miller VM, Gouvion CM, Davidson BL, Paulson HL: Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles. Nucleic Acids Res 2004, 32(2):661-668.
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.2
, pp. 661-668
-
-
Miller, V.M.1
Gouvion, C.M.2
Davidson, B.L.3
Paulson, H.L.4
-
57
-
-
0036618224
-
Overexpression of 5-HTIB receptor in dorsal raphe nucleus using Herpes Simplex Virus gene transfer increases anxiety behavior after inescapable stress
-
Clark MS, Sexton TJ, McClain M, Root D, Kohen R, Neumaier JF: Overexpression of 5-HTIB receptor in dorsal raphe nucleus using Herpes Simplex Virus gene transfer increases anxiety behavior after inescapable stress. J Neurosci 2002, 22(11):4550-4562.
-
(2002)
J Neurosci
, vol.22
, Issue.11
, pp. 4550-4562
-
-
Clark, M.S.1
Sexton, T.J.2
McClain, M.3
Root, D.4
Kohen, R.5
Neumaier, J.F.6
-
58
-
-
0029990068
-
Generation of high-titer defective HSV-I vectors using an IE 2 deletion mutant and quantitative study of expression in cultured cortical cells
-
Lim F, Hartley D, Starr P, Lang P, Song S, Yu L, Wang Y, Geller AI: Generation of high-titer defective HSV-I vectors using an IE 2 deletion mutant and quantitative study of expression in cultured cortical cells. Biotechniques 1996, 20(3):460-469.
-
(1996)
Biotechniques
, vol.20
, Issue.3
, pp. 460-469
-
-
Lim, F.1
Hartley, D.2
Starr, P.3
Lang, P.4
Song, S.5
Yu, L.6
Wang, Y.7
Geller, A.I.8
-
59
-
-
0036727463
-
Presenilins are not required for A beta 42 production in the early secretory pathway
-
Wilson CA, Doms RW, Zheng H, Lee VM: Presenilins are not required for A beta 42 production in the early secretory pathway. Nat Neurosci 2002, 5(9):849-855.
-
(2002)
Nat Neurosci
, vol.5
, Issue.9
, pp. 849-855
-
-
Wilson, C.A.1
Doms, R.W.2
Zheng, H.3
Lee, V.M.4
-
60
-
-
31944449213
-
An early specific cell-cell interaction occurs in the production of beta-amyloid in cell cultures
-
Dewji NN, Mukhopadhyay D, Singer SJ: An early specific cell-cell interaction occurs in the production of beta-amyloid in cell cultures. Proc Natl Acad Sci USA 2006, 103(5):1540-1545.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.5
, pp. 1540-1545
-
-
Dewji, N.N.1
Mukhopadhyay, D.2
Singer, S.J.3
-
61
-
-
0029665851
-
Electrophoretic separation of betaA4 peptides (1-40) and
-
Klafki HW, Wiltfang J, Staufenbiel M: Electrophoretic separation of betaA4 peptides (1-40) and (1-42). Anal Biochem 1996, 237(1):24-29.
-
(1996)
Anal Biochem
, vol.237
, Issue.1
, pp. 24-29
-
-
Klafki, H.W.1
Wiltfang, J.2
Staufenbiel, M.3
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