CD147 is a regulatory subunit of the γ-secretase complex in Alzheimer's disease amyloid β-peptide production

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 21, 2005, Pages 7499-7504

  Zhou, Shuxia ^a   Zhou, Hua ^a   Walian, Peter J ^a   Jap, Bing K ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

Aspartyl protease; Membrane protein complex; Membrane protein purification

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; BETA SECRETASE; CD147 ANTIGEN; GAMMA SECRETASE; GLYCOPROTEIN; MEMBRANE PROTEIN; NICASTRIN; PRESENILIN 1; PRESENILIN ENHANCER 2; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CELL LINE; CELL STRAIN HEK293; ENZYME PURIFICATION; HELA CELL; HUMAN; HUMAN CELL; NERVE CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS; QUANTITATIVE ASSAY; RNA INTERFERENCE; WESTERN BLOTTING;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANTIGENS, CD; ANTIGENS, CD147; ASPARTIC ENDOPEPTIDASES; BLOTTING, WESTERN; CELL MEMBRANE; ENDOPEPTIDASES; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; OLIGONUCLEOTIDES; RECEPTORS, CELL SURFACE; RNA INTERFERENCE;

EID: 19644389648     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0502768102     Document Type: Article

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