-
1
-
-
0022495870
-
Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
-
Adachi, A., H. E. Gendelman, S. Koenig, T. Folks, R. Willey, A. Rabson, and M. A. Martin. 1986. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59:284-291.
-
(1986)
J. Virol
, vol.59
, pp. 284-291
-
-
Adachi, A.1
Gendelman, H.E.2
Koenig, S.3
Folks, T.4
Willey, R.5
Rabson, A.6
Martin, M.A.7
-
2
-
-
0031872106
-
Regions of human immunodeficiency virus type 1 nef required for function in vivo
-
Aldrovandi, G. M., L. Gao, G. Bristol, and J. A. Zack. 1998. Regions of human immunodeficiency virus type 1 nef required for function in vivo. J. Virol. 72:7032-7039.
-
(1998)
J. Virol
, vol.72
, pp. 7032-7039
-
-
Aldrovandi, G.M.1
Gao, L.2
Bristol, G.3
Zack, J.A.4
-
3
-
-
0027209701
-
Nef from primary isolates of human immunodeficiency virus type 1 suppresses surface CD4 expression in human and mouse T cells
-
Anderson, S., D. C. Shugars, R. Swanstrom, and J. V. Garcia. 1993. Nef from primary isolates of human immunodeficiency virus type 1 suppresses surface CD4 expression in human and mouse T cells. J. Virol. 67:4923-4931.
-
(1993)
J. Virol
, vol.67
, pp. 4923-4931
-
-
Anderson, S.1
Shugars, D.C.2
Swanstrom, R.3
Garcia, J.V.4
-
4
-
-
0141780822
-
Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication
-
Arganaraz, E. R., M. Schindler, F. Kirchhoff, M. J. Cortes, and J. Lama. 2003. Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication. J. Biol. Chem. 278:33912-33919.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 33912-33919
-
-
Arganaraz, E.R.1
Schindler, M.2
Kirchhoff, F.3
Cortes, M.J.4
Lama, J.5
-
5
-
-
0024230390
-
Incubation periods for paediatric AIDS patients
-
Auger, I., P. Thomas, V. De Gruttola, D. Morse, D. Moore, R. T. B. Williams, and C. E. Lawrence. 1988. Incubation periods for paediatric AIDS patients. Nature 336:575-577.
-
(1988)
Nature
, vol.336
, pp. 575-577
-
-
Auger, I.1
Thomas, P.2
De Gruttola, V.3
Morse, D.4
Moore, D.5
Williams, R.T.B.6
Lawrence, C.E.7
-
6
-
-
0025818336
-
In vitro macrophage tropism of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac)
-
Banapour, B., M. L. Marthas, R. J. Munn, and P. A. Luciw. 1991. In vitro macrophage tropism of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac). Virology 183:12-19.
-
(1991)
Virology
, vol.183
, pp. 12-19
-
-
Banapour, B.1
Marthas, M.L.2
Munn, R.J.3
Luciw, P.A.4
-
7
-
-
0027370209
-
CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration
-
Brady, H. J., D. J. Pennington, C. G. Miles, and E. A. Dzierzak. 1993. CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration. EMBO J. 12:4923-4932.
-
(1993)
EMBO J
, vol.12
, pp. 4923-4932
-
-
Brady, H.J.1
Pennington, D.J.2
Miles, C.G.3
Dzierzak, E.A.4
-
8
-
-
0028244292
-
Long-term HIV-1 infection without immunologic progression
-
Buchbinder, S. P., M. H. Katz, N. A. Hessol, P. M. O'Malley, and S. D. Holmberg. 1994. Long-term HIV-1 infection without immunologic progression. AIDS 8:1123-1128.
-
(1994)
AIDS
, vol.8
, pp. 1123-1128
-
-
Buchbinder, S.P.1
Katz, M.H.2
Hessol, N.A.3
O'Malley, P.M.4
Holmberg, S.D.5
-
9
-
-
0026088713
-
Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeys
-
Burns, D. P., and R. C. Desrosiers. 1991. Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeys. J. Virol. 65:1843-1854.
-
(1991)
J. Virol
, vol.65
, pp. 1843-1854
-
-
Burns, D.P.1
Desrosiers, R.C.2
-
10
-
-
0028847578
-
Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection
-
Cao, Y., L. Qin, L. Zhang, J. Safrit, and D. Ho. 1995. Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection. N. Engl. J. Med. 332:201-208.
-
(1995)
N. Engl. J. Med
, vol.332
, pp. 201-208
-
-
Cao, Y.1
Qin, L.2
Zhang, L.3
Safrit, J.4
Ho, D.5
-
11
-
-
0035082266
-
Modulation of different human immunodeficiency virus type 1 Nef functions during progression to AIDS
-
Carl, S., T. C. Greenough, M. Krumbiegel, M. Greenberg, J. Skowronski, J. L. Sullivan, and F. Kirchhoff. 2001. Modulation of different human immunodeficiency virus type 1 Nef functions during progression to AIDS. J. Virol. 75:3657-3665.
-
(2001)
J. Virol
, vol.75
, pp. 3657-3665
-
-
Carl, S.1
Greenough, T.C.2
Krumbiegel, M.3
Greenberg, M.4
Skowronski, J.5
Sullivan, J.L.6
Kirchhoff, F.7
-
12
-
-
0037999096
-
Structural defects and variations in the HIV-1 nef gene from rapid, slow and nonprogressor children
-
Casartelli, N., G. Di Matteo, C. Argentini, C. Cancrini, S. Bernardi, G. Castelli, G. Scarlatti, A. Plebani, P. Rossi, and M. Doria. 2003. Structural defects and variations in the HIV-1 nef gene from rapid, slow and nonprogressor children. AIDS 17:1291-1301.
-
(2003)
AIDS
, vol.17
, pp. 1291-1301
-
-
Casartelli, N.1
Di Matteo, G.2
Argentini, C.3
Cancrini, C.4
Bernardi, S.5
Castelli, G.6
Scarlatti, G.7
Plebani, A.8
Rossi, P.9
Doria, M.10
-
13
-
-
0142060865
-
CD4 and major histocompatibility complex class I downregulation by the human immunodeficiency virus type 1 Nef protein in pediatric AIDS progression
-
Casartelli, N., G. Di Matteo, M. Potesta, P. Rossi, and M. Doria. 2003. CD4 and major histocompatibility complex class I downregulation by the human immunodeficiency virus type 1 Nef protein in pediatric AIDS progression. J. Virol. 77:11536-11545.
-
(2003)
J. Virol
, vol.77
, pp. 11536-11545
-
-
Casartelli, N.1
Di Matteo, G.2
Potesta, M.3
Rossi, P.4
Doria, M.5
-
14
-
-
0024829082
-
Differential effects of nef on HIV replication: Implications for viral pathogenesis in the host
-
Cheng-Mayer, C., P. Iannello, K. Shaw, P. A. Luciw, and J. A. Levy. 1989. Differential effects of nef on HIV replication: implications for viral pathogenesis in the host. Science 246:1629-1632.
-
(1989)
Science
, vol.246
, pp. 1629-1632
-
-
Cheng-Mayer, C.1
Iannello, P.2
Shaw, K.3
Luciw, P.A.4
Levy, J.A.5
-
15
-
-
0028804160
-
Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
-
Deacon, N. J., A. Tsykin, A. Solomon, K. Smith, M. Ludford-Menting, D. J. Hooker, D. A. McPhee, A. L. Greenway, A. Ellett, C. Chatfield, et al. 1995. Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients. Science 270:988-991.
-
(1995)
Science
, vol.270
, pp. 988-991
-
-
Deacon, N.J.1
Tsykin, A.2
Solomon, A.3
Smith, K.4
Ludford-Menting, M.5
Hooker, D.J.6
McPhee, D.A.7
Greenway, A.L.8
Ellett, A.9
Chatfield, C.10
-
16
-
-
0001633495
-
Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene
-
Dean, M., M. Carrington, C. Winkler, G. A. Huttley, M. W. Smith, R. Allikmets, J. J. Goedert, S. P. Buchbinder, E. Vittinghoff, E. Gomperts, S. Donfield, D. Vlahov, R. Kaslow, A. Saah, C. Rinaldo, R. Detels, S. J. O'Brien, et al. 1996. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Science 273:1856-1862.
-
(1996)
Science
, vol.273
, pp. 1856-1862
-
-
Dean, M.1
Carrington, M.2
Winkler, C.3
Huttley, G.A.4
Smith, M.W.5
Allikmets, R.6
Goedert, J.J.7
Buchbinder, S.P.8
Vittinghoff, E.9
Gomperts, E.10
Donfield, S.11
Vlahov, D.12
Kaslow, R.13
Saah, A.14
Rinaldo, C.15
Detels, R.16
O'Brien, S.J.17
-
17
-
-
0034890660
-
Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor
-
Derdeyn, C. A., J. M. Decker, J. N. Sfakianos, Z. Zhang, W. A. O'Brien, L. Ratner, G. M. Shaw, and E. Hunter. 2001. Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor. J. Virol. 75:8605-8614.
-
(2001)
J. Virol
, vol.75
, pp. 8605-8614
-
-
Derdeyn, C.A.1
Decker, J.M.2
Sfakianos, J.N.3
Zhang, Z.4
O'Brien, W.A.5
Ratner, L.6
Shaw, G.M.7
Hunter, E.8
-
18
-
-
0037090333
-
Mucosal candidiasis in transgenic mice expressing human immunodeficiency virus type 1
-
de Repentigny, L., F. Aumont, J.-S. Ripeau, M. Fiorillo, D. G. Kay, Z. Hanna, and P. Jolicoeur. 2002. Mucosal candidiasis in transgenic mice expressing human immunodeficiency virus type 1. J. Infect. Dis. 185:1103-1114.
-
(2002)
J. Infect. Dis
, vol.185
, pp. 1103-1114
-
-
de Repentigny, L.1
Aumont, F.2
Ripeau, J.-S.3
Fiorillo, M.4
Kay, D.G.5
Hanna, Z.6
Jolicoeur, P.7
-
19
-
-
0026717493
-
Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes
-
de Ronde, A., B. Klaver, W. Keulen, L. Smit, and J. Goudsmit. 1992. Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes. Virology 188:391-395.
-
(1992)
Virology
, vol.188
, pp. 391-395
-
-
de Ronde, A.1
Klaver, B.2
Keulen, W.3
Smit, L.4
Goudsmit, J.5
-
20
-
-
0030055826
-
HIV type 1 Nef perturbs eye lens development in transgenic mice
-
Dickie, P. 1996. HIV type 1 Nef perturbs eye lens development in transgenic mice. AIDS Res. Hum. Retrovir. 12:177-189.
-
(1996)
AIDS Res. Hum. Retrovir
, vol.12
, pp. 177-189
-
-
Dickie, P.1
-
21
-
-
0034690773
-
Nef modulation of HIV type 1 gene expression and cytopathicity in tissues of HIV transgenic mice
-
Dickie, P. 2000. Nef modulation of HIV type 1 gene expression and cytopathicity in tissues of HIV transgenic mice. AIDS Res. Hum. Retrovir. 16:777-790.
-
(2000)
AIDS Res. Hum. Retrovir
, vol.16
, pp. 777-790
-
-
Dickie, P.1
-
23
-
-
0029089406
-
Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys
-
Du, Z., S. M. Lang, V. G. Sasseville, A. Lackner, P. O. Ilyinskii, M. D. J. J. Daniel, and R. C. Desrosiers. 1995. Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys. Cell 82:665-674.
-
(1995)
Cell
, vol.82
, pp. 665-674
-
-
Du, Z.1
Lang, S.M.2
Sasseville, V.G.3
Lackner, A.4
Ilyinskii, P.O.5
Daniel, M.D.J.J.6
Desrosiers, R.C.7
-
24
-
-
0028307509
-
Non-progression in HIV infection
-
Easterbrook, P. J. 1994. Non-progression in HIV infection. AIDS 8:1179-1182.
-
(1994)
AIDS
, vol.8
, pp. 1179-1182
-
-
Easterbrook, P.J.1
-
25
-
-
0035928809
-
A natural variability in the proline-rich motif of Nef modulates HIV-1 replication in primary T cells
-
Fackler, O. T., D. Wolf, H. O. Weber, B. Laffert, P. D'Aloja, B. Schuler-Thurner, R. Geffin, K. Saksela, M. Geyer, B. M. Peterlin, G. Schuler, and A. S. Baur. 2001. A natural variability in the proline-rich motif of Nef modulates HIV-1 replication in primary T cells. Curr. Biol. 11:1294-1299.
-
(2001)
Curr. Biol
, vol.11
, pp. 1294-1299
-
-
Fackler, O.T.1
Wolf, D.2
Weber, H.O.3
Laffert, B.4
D'Aloja, P.5
Schuler-Thurner, B.6
Geffin, R.7
Saksela, K.8
Geyer, M.9
Peterlin, B.M.10
Schuler, G.11
Baur, A.S.12
-
26
-
-
0029805203
-
Host factors and the pathogenesis of HIV-induced disease
-
Fauci, A. S. 1996. Host factors and the pathogenesis of HIV-induced disease. Nature 384:529-534.
-
(1996)
Nature
, vol.384
, pp. 529-534
-
-
Fauci, A.S.1
-
27
-
-
0029963323
-
Immunopathogenic mechanisms of HIV infection
-
Fauci, A. S., G. Pantaleo, S. Stanley, and D. Weissman. 1996. Immunopathogenic mechanisms of HIV infection. Ann. Intern. Med. 124:654-663.
-
(1996)
Ann. Intern. Med
, vol.124
, pp. 654-663
-
-
Fauci, A.S.1
Pantaleo, G.2
Stanley, S.3
Weissman, D.4
-
28
-
-
0035138509
-
Genetic and functional diversity of human immunodeficiency virus type 1 subtype B Nef primary isolates
-
Foster, J. L., R. P. Molina, T. Luo, V. K. Arora, Y. Huang, D. D. Ho, and J. V. Garcia. 2001. Genetic and functional diversity of human immunodeficiency virus type 1 subtype B Nef primary isolates. J. Virol. 75:1672-1680.
-
(2001)
J. Virol
, vol.75
, pp. 1672-1680
-
-
Foster, J.L.1
Molina, R.P.2
Luo, T.3
Arora, V.K.4
Huang, Y.5
Ho, D.D.6
Garcia, J.V.7
-
29
-
-
0034693935
-
Functional and structural defects in HIV type 1 nef genes derived from pediatric long-term survivors
-
Geffin, R., D. Wolf, R. Muller, M. D. Hill, E. Stellwag, M. Freitag, G. Sass, G. B. Scott, and A. S. Baur. 2000. Functional and structural defects in HIV type 1 nef genes derived from pediatric long-term survivors. AIDS Res. Hum. Retrovir. 16:1855-1868.
-
(2000)
AIDS Res. Hum. Retrovir
, vol.16
, pp. 1855-1868
-
-
Geffin, R.1
Wolf, D.2
Muller, R.3
Hill, M.D.4
Stellwag, E.5
Freitag, M.6
Sass, G.7
Scott, G.B.8
Baur, A.S.9
-
31
-
-
0032525137
-
The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes
-
Greenberg, M. E., A. J. Iafrate, and J. Skowronski. 1998. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes. EMBO J. 17:2777-2789.
-
(1998)
EMBO J
, vol.17
, pp. 2777-2789
-
-
Greenberg, M.E.1
Iafrate, A.J.2
Skowronski, J.3
-
32
-
-
0028363597
-
Nef 27, but not the Nef 25 isoform of human immunodeficiency virus-type 1 pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells
-
Greenway, A. L., D. A. McPhee, E. Grgacic, D. Hewish, A. Lucantoni, and I. A. A. Macreadie. 1994. Nef 27, but not the Nef 25 isoform of human immunodeficiency virus-type 1 pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells. Virology 198:245-256.
-
(1994)
Virology
, vol.198
, pp. 245-256
-
-
Greenway, A.L.1
McPhee, D.A.2
Grgacic, E.3
Hewish, D.4
Lucantoni, A.5
Macreadie, I.A.A.6
-
34
-
-
0031964791
-
Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like disease
-
Hanna, Z., D. G. Kay, M. Cool, S. Jothy, N. Rebai, and P. Jolicoeur. 1998. Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like disease. J. Virol. 72:121-132.
-
(1998)
J. Virol
, vol.72
, pp. 121-132
-
-
Hanna, Z.1
Kay, D.G.2
Cool, M.3
Jothy, S.4
Rebai, N.5
Jolicoeur, P.6
-
35
-
-
0032538278
-
Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
-
Hanna, Z., D. G. Kay, N. Rebai, A. Guimond, S. Jothy, and P. Jolicoeur. 1998. Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice. Cell 95:163-175.
-
(1998)
Cell
, vol.95
, pp. 163-175
-
-
Hanna, Z.1
Kay, D.G.2
Rebai, N.3
Guimond, A.4
Jothy, S.5
Jolicoeur, P.6
-
36
-
-
32844464362
-
HIV-1 Nef mutations abrogating downregulation of CD4 affect other Nef functions and show reduced pathogenicity in transgenic mice
-
Hanna, Z., E. Priceputu, C. Hu, P. Vincent, and P. Jolicoeur. 2006. HIV-1 Nef mutations abrogating downregulation of CD4 affect other Nef functions and show reduced pathogenicity in transgenic mice. Virology 346:40-52.
-
(2006)
Virology
, vol.346
, pp. 40-52
-
-
Hanna, Z.1
Priceputu, E.2
Hu, C.3
Vincent, P.4
Jolicoeur, P.5
-
37
-
-
4444273413
-
In vivo mutational analysis of the N-terminal region of HIV-1 Nef reveals critical motifs for the development of an AIDS-like disease in CD4C/HIV transgenic mice
-
Hanna, Z., E. Priceputu, D. G. Kay, J. Poudrier, P. Chrobak, and P. Jolicoeur. 2004. In vivo mutational analysis of the N-terminal region of HIV-1 Nef reveals critical motifs for the development of an AIDS-like disease in CD4C/HIV transgenic mice. Virology 327:273-286.
-
(2004)
Virology
, vol.327
, pp. 273-286
-
-
Hanna, Z.1
Priceputu, E.2
Kay, D.G.3
Poudrier, J.4
Chrobak, P.5
Jolicoeur, P.6
-
38
-
-
0035496910
-
Distinct regulatory elements are required for faithful expression of human CD4 in T-cells, macrophages and dendritic cells of transgenic mice
-
Hanna, Z., N. Rebai, J. Poudrier, and P. Jolicoeur. 2001. Distinct regulatory elements are required for faithful expression of human CD4 in T-cells, macrophages and dendritic cells of transgenic mice. Blood 98:2275-2278.
-
(2001)
Blood
, vol.98
, pp. 2275-2278
-
-
Hanna, Z.1
Rebai, N.2
Poudrier, J.3
Jolicoeur, P.4
-
40
-
-
0034843329
-
The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck
-
Hanna, Z., X. Weng, D. G. Kay, J. Poudrier, C. Lowell, and P. Jolicoeur. 2001. The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck. J. Virol. 75:9378-9392.
-
(2001)
J. Virol
, vol.75
, pp. 9378-9392
-
-
Hanna, Z.1
Weng, X.2
Kay, D.G.3
Poudrier, J.4
Lowell, C.5
Jolicoeur, P.6
-
42
-
-
16044367526
-
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
-
Huang, Y., W. A. Paxton, S. M. Wolinsky, A. U. Neumann, L. Zhang, T. He, S. Kang, D. Ceradini, Z. Jin, K. Yazdanbakhsh, K. Kunstman, D. Erickson, E. Dragon, N. R. Landau, J. Phair, D. D. Ho, and R. A. Koup. 1996. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat. Med. 2:1240-1243.
-
(1996)
Nat. Med
, vol.2
, pp. 1240-1243
-
-
Huang, Y.1
Paxton, W.A.2
Wolinsky, S.M.3
Neumann, A.U.4
Zhang, L.5
He, T.6
Kang, S.7
Ceradini, D.8
Jin, Z.9
Yazdanbakhsh, K.10
Kunstman, K.11
Erickson, D.12
Dragon, E.13
Landau, N.R.14
Phair, J.15
Ho, D.D.16
Koup, R.A.17
-
43
-
-
0023697159
-
AIDS two months after primary human immunodeficiency virus infection
-
Isaksson, B., J. Albert, F. Chiodi, A. Furucrona, A. Krook, and P. Putkonen. 1988. AIDS two months after primary human immunodeficiency virus infection. J. Infect. Dis. 158:866-868.
-
(1988)
J. Infect. Dis
, vol.158
, pp. 866-868
-
-
Isaksson, B.1
Albert, J.2
Chiodi, F.3
Furucrona, A.4
Krook, A.5
Putkonen, P.6
-
44
-
-
0025996121
-
The genetic fate of molecularly cloned simian immunodeficiency virus in experimentally infected macaques
-
Johnson, P. R., T. E. Hamm, S. Goldstein, S. Kitov, and V. M. Hirsch. 1991. The genetic fate of molecularly cloned simian immunodeficiency virus in experimentally infected macaques. Virology 185:217-228.
-
(1991)
Virology
, vol.185
, pp. 217-228
-
-
Johnson, P.R.1
Hamm, T.E.2
Goldstein, S.3
Kitov, S.4
Hirsch, V.M.5
-
45
-
-
0033109617
-
A novel mouse model of HIV-1 disease
-
Jolicoeur, P., D. G. Kay, M. Cool, S. Jothy, N. Rebai, and Z. Hanna. 1999. A novel mouse model of HIV-1 disease. Leukemia 13:S78-S80.
-
(1999)
Leukemia
, vol.13
-
-
Jolicoeur, P.1
Kay, D.G.2
Cool, M.3
Jothy, S.4
Rebai, N.5
Hanna, Z.6
-
46
-
-
34247646628
-
Cardiac disease in HIV-1 Tg mice
-
R. R. Watson ed, Marcel Dekker Inc, New York, NY
-
Jolicoeur, P., P. Yue, Z. Hanna, M.-C. Simard, and D. G. Kay. 2004. Cardiac disease in HIV-1 Tg mice, p. 377-386. In R. R. Watson (ed.), AIDS and heart disease. Marcel Dekker Inc., New York, NY.
-
(2004)
AIDS and heart disease
, pp. 377-386
-
-
Jolicoeur, P.1
Yue, P.2
Hanna, Z.3
Simard, M.-C.4
Kay, D.G.5
-
47
-
-
0033855793
-
Glomerulosclerosis and viral gene expression in HIV-transgenic mice: Role of nef
-
Kajiyama, W., J. B. Kopp, N. J. Marinos, P. E. Klotman, and P. Dickie. 2000. Glomerulosclerosis and viral gene expression in HIV-transgenic mice: role of nef. Kidney Int. 58:1148-1159.
-
(2000)
Kidney Int
, vol.58
, pp. 1148-1159
-
-
Kajiyama, W.1
Kopp, J.B.2
Marinos, N.J.3
Klotman, P.E.4
Dickie, P.5
-
48
-
-
0030820125
-
+ T cells in vitro and in vivo
-
+ T cells in vitro and in vivo. J. Virol. 71:8456-8466.
-
(1997)
J. Virol
, vol.71
, pp. 8456-8466
-
-
Kawano, Y.1
Tanaka, Y.2
Misawa, N.3
Tanaka, R.4
Kira, J.I.5
Kimura, T.6
Fukushi, M.7
Sano, K.8
Goto, T.9
Nakai, M.10
Kobayashi, T.11
Yamamoto, N.12
Koyanagi, Y.13
-
49
-
-
0036313609
-
Cardiac disease in transgenic mice expressing human immunodeficiency virus-1 Nef in cells of the immune system
-
Kay, D. G., P. Yue, Z. Hanna, S. Jothy, E. Tremblay, and P. Jolicoeur. 2002. Cardiac disease in transgenic mice expressing human immunodeficiency virus-1 Nef in cells of the immune system. Am. J. Pathol. 161:321-335.
-
(2002)
Am. J. Pathol
, vol.161
, pp. 321-335
-
-
Kay, D.G.1
Yue, P.2
Hanna, Z.3
Jothy, S.4
Tremblay, E.5
Jolicoeur, P.6
-
50
-
-
0024328854
-
Use of infectious molecular clones of simian immunodeficiency virus for pathogenesis studies
-
Kestler, H. W., Y. N. Naidu, T. Kodama, N. W. King, M. D. Daniel, Y. Li, and R. C. Desrosiers. 1989. Use of infectious molecular clones of simian immunodeficiency virus for pathogenesis studies. J. Med. Primatol. 18:305-309.
-
(1989)
J. Med. Primatol
, vol.18
, pp. 305-309
-
-
Kestler, H.W.1
Naidu, Y.N.2
Kodama, T.3
King, N.W.4
Daniel, M.D.5
Li, Y.6
Desrosiers, R.C.7
-
51
-
-
0025743306
-
Importance of the nef gene for maintenance of high virus loads and for development of AIDS
-
Kestler, H. W., D. J. Ringler, K. Mori, D. L. Panicali, P. K. Sehgal, M. D. Daniel, and R. C. Desrosiers. 1991. Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell 65:651-662.
-
(1991)
Cell
, vol.65
, pp. 651-662
-
-
Kestler, H.W.1
Ringler, D.J.2
Mori, K.3
Panicali, D.L.4
Sehgal, P.K.5
Daniel, M.D.6
Desrosiers, R.C.7
-
52
-
-
0033052038
-
Sequence variations in human immunodeficiency virus type 1 Nef are associated with different stages of disease
-
Kirchhoff, F., P. J. Easterbrook, N. Douglas, M. Troop, T. C. Greenough, J. Weber, S. Carl, J. L. Sullivan, and R. S. Daniels. 1999. Sequence variations in human immunodeficiency virus type 1 Nef are associated with different stages of disease. J. Virol. 73:5497-5508.
-
(1999)
J. Virol
, vol.73
, pp. 5497-5508
-
-
Kirchhoff, F.1
Easterbrook, P.J.2
Douglas, N.3
Troop, M.4
Greenough, T.C.5
Weber, J.6
Carl, S.7
Sullivan, J.L.8
Daniels, R.S.9
-
53
-
-
0028835788
-
Brief report: Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
-
Kirchhoff, F., T. C. Greenough, D. B. Brettler, J. L. Sullivan, and R. C. Desrosiers. 1995. Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N. Engl. J. Med. 332:228-232.
-
(1995)
N. Engl. J. Med
, vol.332
, pp. 228-232
-
-
Kirchhoff, F.1
Greenough, T.C.2
Brettler, D.B.3
Sullivan, J.L.4
Desrosiers, R.C.5
-
54
-
-
2942687028
-
Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors
-
Kirchhoff, F., M. Schindler, N. Bailer, G. H. Renkema, K. Saksela, V. Knoop, M. C. Muller-Trutwin, M. L. Santiago, F. Bibollet-Ruche, M. T. Dittmar, J. L. Heeney, B. H. Hahn, and J. Munch. 2004. Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors. J. Virol. 78:6864-6874.
-
(2004)
J. Virol
, vol.78
, pp. 6864-6874
-
-
Kirchhoff, F.1
Schindler, M.2
Bailer, N.3
Renkema, G.H.4
Saksela, K.5
Knoop, V.6
Muller-Trutwin, M.C.7
Santiago, M.L.8
Bibollet-Ruche, F.9
Dittmar, M.T.10
Heeney, J.L.11
Hahn, B.H.12
Munch, J.13
-
55
-
-
0029825711
-
Early progression of disease in HIV-infected infants with thymus dysfunction
-
Kourtis, A. P., C. Ibegbu, A. J. Nahmias, F. K. Lee, W. S. Clark, M. K. Sawyer, and S. Nesheim. 1996. Early progression of disease in HIV-infected infants with thymus dysfunction. N. Engl. J. Med. 335:1431-1436.
-
(1996)
N. Engl. J. Med
, vol.335
, pp. 1431-1436
-
-
Kourtis, A.P.1
Ibegbu, C.2
Nahmias, A.J.3
Lee, F.K.4
Clark, W.S.5
Sawyer, M.K.6
Nesheim, S.7
-
56
-
-
0023214674
-
Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms
-
Koyanagi, Y., S. Miles, R. T. Mitsuyasu, J. E. Merrill, H. V. Vinters, and I. S. Chen. 1987. Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science 236:819-822.
-
(1987)
Science
, vol.236
, pp. 819-822
-
-
Koyanagi, Y.1
Miles, S.2
Mitsuyasu, R.T.3
Merrill, J.E.4
Vinters, H.V.5
Chen, I.S.6
-
57
-
-
0031827420
-
Mice transgenic for simian immunodeficiency virus nef are immunologically compromised
-
Larsen, N. B., H. W. Kestler, and J. J. Docherty. 1998. Mice transgenic for simian immunodeficiency virus nef are immunologically compromised. J. Biomed. Sci. 5:260-266.
-
(1998)
J. Biomed. Sci
, vol.5
, pp. 260-266
-
-
Larsen, N.B.1
Kestler, H.W.2
Docherty, J.J.3
-
58
-
-
0033519616
-
Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort
-
Learmont, J. C., A. F. Geczy, J. Mills, L. J. Ashton, C. H. Raynes-Greenow, R. J. Garsia, W. B. Dyer, L. McIntyre, R. B. Oelrichs, D. I. Rhodes, N. J. Deacon, and J. S. Sullivan. 1999. Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort. N. Engl. J. Med. 340:1715-1722.
-
(1999)
N. Engl. J. Med
, vol.340
, pp. 1715-1722
-
-
Learmont, J.C.1
Geczy, A.F.2
Mills, J.3
Ashton, L.J.4
Raynes-Greenow, C.H.5
Garsia, R.J.6
Dyer, W.B.7
McIntyre, L.8
Oelrichs, R.B.9
Rhodes, D.I.10
Deacon, N.J.11
Sullivan, J.S.12
-
59
-
-
0031039987
-
Analysis of Nef-induced MHC-I endocytosis
-
Le Gall, S., J. M. Heard, and O. Schwartz. 1997. Analysis of Nef-induced MHC-I endocytosis. Res. Virol. 148:43-47.
-
(1997)
Res. Virol
, vol.148
, pp. 43-47
-
-
Le Gall, S.1
Heard, J.M.2
Schwartz, O.3
-
60
-
-
0021150629
-
Isolation of lymphocytopathic retroviruses from San Francisco patients with AIDS
-
Levy, J. A., A. D. Hoffman, S. M. Kramer, J. A. Landis, J. M. Shimabukuro, and L. S. Oshiro. 1984. Isolation of lymphocytopathic retroviruses from San Francisco patients with AIDS. Science 225:840-842.
-
(1984)
Science
, vol.225
, pp. 840-842
-
-
Levy, J.A.1
Hoffman, A.D.2
Kramer, S.M.3
Landis, J.A.4
Shimabukuro, J.M.5
Oshiro, L.S.6
-
61
-
-
0026726809
-
Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: Evidence for limited defectiveness and complementation
-
Li, Y., H. Hui, C. J. Burgess, R. W. Price, P. M. Sharp, B. H. Hahn, and G. M. Shaw. 1992. Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: evidence for limited defectiveness and complementation. J. Virol. 66:6587-6600.
-
(1992)
J. Virol
, vol.66
, pp. 6587-6600
-
-
Li, Y.1
Hui, H.2
Burgess, C.J.3
Price, R.W.4
Sharp, P.M.5
Hahn, B.H.6
Shaw, G.M.7
-
62
-
-
0025815375
-
Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: Identification of replication-competent and -defective viral genomes
-
Li, Y. X., J. C. Kappes, J. A. Conway, R. W. Price, G. M. Shaw, and B. H. Hahn. 1991. Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes. J. Virol. 65:3973-3985.
-
(1991)
J. Virol
, vol.65
, pp. 3973-3985
-
-
Li, Y.X.1
Kappes, J.C.2
Conway, J.A.3
Price, R.W.4
Shaw, G.M.5
Hahn, B.H.6
-
63
-
-
0024262996
-
The natural history of human immunodeficiency virus infection
-
Lifson, A. R., G. W. Rutherford, and H. W. Jaffe. 1988. The natural history of human immunodeficiency virus infection. J. Infect. Dis. 158:1360-1367.
-
(1988)
J. Infect. Dis
, vol.158
, pp. 1360-1367
-
-
Lifson, A.R.1
Rutherford, G.W.2
Jaffe, H.W.3
-
64
-
-
0027955426
-
Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3′-long terminal repeat transgene
-
Lindemann, D., R. Wilhelm, P. Renard, A. Althage, R. Zinkernagel, and J. Mous. 1994. Severe immunodeficiency associated with a human immunodeficiency virus 1 NEF/3′-long terminal repeat transgene. J. Exp. Med. 179:797-807.
-
(1994)
J. Exp. Med
, vol.179
, pp. 797-807
-
-
Lindemann, D.1
Wilhelm, R.2
Renard, P.3
Althage, A.4
Zinkernagel, R.5
Mous, J.6
-
65
-
-
15844388931
-
Homozygous defect in hiv-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
-
Liu, R., W. A. Paxton, S. Choe, D. Ceradini, S. R. Martin, R. Horuk, M. E. MacDonald, H. Stuhlmann, R. A. Koup, and N. R. Landau. 1996. Homozygous defect in hiv-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86:367-377.
-
(1996)
Cell
, vol.86
, pp. 367-377
-
-
Liu, R.1
Paxton, W.A.2
Choe, S.3
Ceradini, D.4
Martin, S.R.5
Horuk, R.6
MacDonald, M.E.7
Stuhlmann, H.8
Koup, R.A.9
Landau, N.R.10
-
66
-
-
0026608313
-
Genetic and biological comparisons of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac)
-
Luciw, P. A., K. E. Shaw, R. E. Unger, V. Planelles, M. W. Stout, J. E. Lackner, E. Pratt-Lowe, N. J. Leung, B. Banapour, and M. L. Marthas. 1992. Genetic and biological comparisons of pathogenic and nonpathogenic molecular clones of simian immunodeficiency virus (SIVmac). AIDS Res. Hum. Retrovir. 8:395-402.
-
(1992)
AIDS Res. Hum. Retrovir
, vol.8
, pp. 395-402
-
-
Luciw, P.A.1
Shaw, K.E.2
Unger, R.E.3
Planelles, V.4
Stout, M.W.5
Lackner, J.E.6
Pratt-Lowe, E.7
Leung, N.J.8
Banapour, B.9
Marthas, M.L.10
-
67
-
-
0035995683
-
Presence of intact vpu and nef genes in nonpathogenic SHIV is essential for acquisition of pathogenicity of this virus by serial passage in macaques
-
Mackay, G. A., Y. Niu, Z. Q. Liu, S. Mukherjee, Z. Li, I. Adany, S. Buch, W. Zhuge, H. M. McClure, O. Narayan, and M. S. Smith. 2002. Presence of intact vpu and nef genes in nonpathogenic SHIV is essential for acquisition of pathogenicity of this virus by serial passage in macaques. Virology 295:133-146.
-
(2002)
Virology
, vol.295
, pp. 133-146
-
-
Mackay, G.A.1
Niu, Y.2
Liu, Z.Q.3
Mukherjee, S.4
Li, Z.5
Adany, I.6
Buch, S.7
Zhuge, W.8
McClure, H.M.9
Narayan, O.10
Smith, M.S.11
-
68
-
-
0029846223
-
High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection
-
Mariani, R., F. Kirchhoff, T. C. Greenough, J. L. Sullivan, R. C. Desrosiers, and J. Skowronski. 1996. High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection. J. Virol. 70:7752-7764.
-
(1996)
J. Virol
, vol.70
, pp. 7752-7764
-
-
Mariani, R.1
Kirchhoff, F.2
Greenough, T.C.3
Sullivan, J.L.4
Desrosiers, R.C.5
Skowronski, J.6
-
69
-
-
0027315870
-
CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals
-
Mariani, R., and J. Skowronski. 1993. CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals. Proc. Natl. Acad. Sci. USA 90:5549-5553.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5549-5553
-
-
Mariani, R.1
Skowronski, J.2
-
70
-
-
0031449498
-
Thymic function in HIV-1 disease
-
McCune, J. M. 1997. Thymic function in HIV-1 disease. Semin. Immunol. 9:397-404.
-
(1997)
Semin. Immunol
, vol.9
, pp. 397-404
-
-
McCune, J.M.1
-
71
-
-
0035912232
-
The dynamics of CD4+ T-cell depletion in HIV disease
-
McCune, J. M. 2001. The dynamics of CD4+ T-cell depletion in HIV disease. Nature 410:974-979.
-
(2001)
Nature
, vol.410
, pp. 974-979
-
-
McCune, J.M.1
-
72
-
-
0025216459
-
Rapid clinical and laboratory progression of HIV infection
-
McLean, K. A., D. A. Holmes, B. A. Evans, L. McAlpine, R. Thorp, J. V. Parry, and M. G. Glaser. 1990. Rapid clinical and laboratory progression of HIV infection. AIDS 4:369-371.
-
(1990)
AIDS
, vol.4
, pp. 369-371
-
-
McLean, K.A.1
Holmes, D.A.2
Evans, B.A.3
McAlpine, L.4
Thorp, R.5
Parry, J.V.6
Glaser, M.G.7
-
73
-
-
0033179134
-
Host genetic influences on HIV-1 pathogenesis
-
Michael, N. L. 1999. Host genetic influences on HIV-1 pathogenesis. Curr. Opin. Immunol. 11:466-474.
-
(1999)
Curr. Opin. Immunol
, vol.11
, pp. 466-474
-
-
Michael, N.L.1
-
74
-
-
0028853962
-
Functional characterization of human immunodeficiency virus type 1 nef genes in patients with divergent rates of disease progression
-
Michael, N. L., G. Chang, L. A. d'Arcy, C. J. Tseng, D. L. Birx, and H. W. Sheppard. 1995. Functional characterization of human immunodeficiency virus type 1 nef genes in patients with divergent rates of disease progression. J. Virol. 69:6758-6769.
-
(1995)
J. Virol
, vol.69
, pp. 6758-6769
-
-
Michael, N.L.1
Chang, G.2
d'Arcy, L.A.3
Tseng, C.J.4
Birx, D.L.5
Sheppard, H.W.6
-
75
-
-
23244465720
-
Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication
-
Munch, J., M. Schindler, S. Wildum, E. Rucker, N. Bailer, V. Knoop, F. J. Novembre, and F. Kirchhoff. 2005. Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication. J. Virol. 79:10547-10560.
-
(2005)
J. Virol
, vol.79
, pp. 10547-10560
-
-
Munch, J.1
Schindler, M.2
Wildum, S.3
Rucker, E.4
Bailer, N.5
Knoop, V.6
Novembre, F.J.7
Kirchhoff, F.8
-
76
-
-
0028939084
-
Long-term survivors with HIV-1 infection: Incubation period and longitudinal patterns of CD4+ lymphocytes
-
Munoz, A., A. J. Kirby, Y. D. He, J. B. Margolick, B. R. Visscher, C. R. Rinaldo, R. A. Kaslow, and J. P. Phair. 1995. Long-term survivors with HIV-1 infection: incubation period and longitudinal patterns of CD4+ lymphocytes. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 8:496-505.
-
(1995)
J. Acquir. Immune Defic. Syndr. Hum. Retrovirol
, vol.8
, pp. 496-505
-
-
Munoz, A.1
Kirby, A.J.2
He, Y.D.3
Margolick, J.B.4
Visscher, B.R.5
Rinaldo, C.R.6
Kaslow, R.A.7
Phair, J.P.8
-
77
-
-
0024397774
-
Acquired immunodeficiency syndrome (AIDS)-free time after human immunodeficiency virus type 1 (HIV-1) seroconversion in homosexual men
-
Munoz, A., M. C. Wang, S. Bass, J. M. Taylor, L. A. Kingsley, J. S. Chmiel, B. F. Polk, et al. 1989. Acquired immunodeficiency syndrome (AIDS)-free time after human immunodeficiency virus type 1 (HIV-1) seroconversion in homosexual men. Am. J. Epidemiol. 130:530-539.
-
(1989)
Am. J. Epidemiol
, vol.130
, pp. 530-539
-
-
Munoz, A.1
Wang, M.C.2
Bass, S.3
Taylor, J.M.4
Kingsley, L.A.5
Chmiel, J.S.6
Polk, B.F.7
-
78
-
-
0029759475
-
Immunological correlates of disease severity in pediatric slow progressors with human immunodeficiency virus type 1 infection
-
Patarca, R., D. Sandler, K. Maher, C. Hutto, N. L. Martin, N. G. Klimas, G. B. Scott, and M. A. Fletcher. 1996. Immunological correlates of disease severity in pediatric slow progressors with human immunodeficiency virus type 1 infection. AIDS Res. Hum. Retrovir. 12:1063-1068.
-
(1996)
AIDS Res. Hum. Retrovir
, vol.12
, pp. 1063-1068
-
-
Patarca, R.1
Sandler, D.2
Maher, K.3
Hutto, C.4
Martin, N.L.5
Klimas, N.G.6
Scott, G.B.7
Fletcher, M.A.8
-
79
-
-
0032999976
-
The downregulation of CD4 and MHC-I by primate lentiviruses: A paradigm for the modulation of cell surface receptors
-
Piguet, V., O. Schwartz, S. Le Gall, and D. Trono. 1999. The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors. Immunol. Rev. 168:51-63.
-
(1999)
Immunol. Rev
, vol.168
, pp. 51-63
-
-
Piguet, V.1
Schwartz, O.2
Le Gall, S.3
Trono, D.4
-
80
-
-
0028835993
-
Markers and determinants of disease progression in children with HIV infection
-
Pizzo, P. A., C. M. Wilfert, et al. 1995. Markers and determinants of disease progression in children with HIV infection. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 8:30-44.
-
(1995)
J. Acquir. Immune Defic. Syndr. Hum. Retrovirol
, vol.8
, pp. 30-44
-
-
Pizzo, P.A.1
Wilfert, C.M.2
-
81
-
-
0031954686
-
Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1
-
Platt, E. J., K. Wehrly, S. E. Kuhmann, B. Chesebro, and D. Kabat. 1998. Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1. J. Virol. 72:2855-2864.
-
(1998)
J. Virol
, vol.72
, pp. 2855-2864
-
-
Platt, E.J.1
Wehrly, K.2
Kuhmann, S.E.3
Chesebro, B.4
Kabat, D.5
-
83
-
-
0034878242
-
The AIDS disease of CD4C/HIV transgenic mice shows impaired germinal centers and autoantibodies and develops in the absence of IFN-γ and IL-6
-
Poudrier, J., X. Weng, D. G. Kay, G. Paré, E. L. Calvo, Z. Hanna, M. H. Kosco-Vilbois, and P. Jolicoeur. 2001. The AIDS disease of CD4C/HIV transgenic mice shows impaired germinal centers and autoantibodies and develops in the absence of IFN-γ and IL-6. Immunity 15:173-185.
-
(2001)
Immunity
, vol.15
, pp. 173-185
-
-
Poudrier, J.1
Weng, X.2
Kay, D.G.3
Paré, G.4
Calvo, E.L.5
Hanna, Z.6
Kosco-Vilbois, M.H.7
Jolicoeur, P.8
-
84
-
-
18144416901
-
The Nef-mediated AIDS-like disease of CD4C/human immunodeficiency virus transgenic mice is associated with increased Fas/FasL expression on T cells and T-cell death but is not prevented in Fas-, FasL-, tumor necrosis factor receptor 1-, or interleukin-1β- converting enzyme-deficient or Bcl2-expressing transgenic mice
-
Priceputu, E., I. Rodrigue, P. Chrobak, J. Poudrier, T. W. Mak, Z. Hanna, C. Hu, D. G. Kay, and P. Jolicoeur. 2005. The Nef-mediated AIDS-like disease of CD4C/human immunodeficiency virus transgenic mice is associated with increased Fas/FasL expression on T cells and T-cell death but is not prevented in Fas-, FasL-, tumor necrosis factor receptor 1-, or interleukin-1β- converting enzyme-deficient or Bcl2-expressing transgenic mice. J. Virol. 79:6377-6391.
-
(2005)
J. Virol
, vol.79
, pp. 6377-6391
-
-
Priceputu, E.1
Rodrigue, I.2
Chrobak, P.3
Poudrier, J.4
Mak, T.W.5
Hanna, Z.6
Hu, C.7
Kay, D.G.8
Jolicoeur, P.9
-
85
-
-
0033766992
-
Characterization of three nef-defective human immunodeficiency virus type 1 strains associated with long-term nonprogression
-
Rhodes, D. I., L. Ashton, A. Solomon, A. Carr, D. Cooper, J. Kaldor, N. Deacon, et al. 2000. Characterization of three nef-defective human immunodeficiency virus type 1 strains associated with long-term nonprogression. J. Virol. 74:10581-10588.
-
(2000)
J. Virol
, vol.74
, pp. 10581-10588
-
-
Rhodes, D.I.1
Ashton, L.2
Solomon, A.3
Carr, A.4
Cooper, D.5
Kaldor, J.6
Deacon, N.7
-
86
-
-
4444245254
-
A naturally occurring variation in the proline-rich region does not attenuate human immunodeficiency virus type 1 nef function
-
Rucker, E., J. Munch, S. Wildum, M. Brenner, J. Eisemann, L. Margolis, and F. Kirchhoff. 2004. A naturally occurring variation in the proline-rich region does not attenuate human immunodeficiency virus type 1 nef function. J. Virol. 78:10197-10201.
-
(2004)
J. Virol
, vol.78
, pp. 10197-10201
-
-
Rucker, E.1
Munch, J.2
Wildum, S.3
Brenner, M.4
Eisemann, J.5
Margolis, L.6
Kirchhoff, F.7
-
87
-
-
0030947411
-
Evolution of human immunodeficiency virus type 1 in perinatally infected infants with rapid and slow progression to disease
-
Salvatori, F., S. Masiero, C. Giaquinto, C. M. Wade, A. J. Brown, L. Chieco-Bianchi, and A. De Rossi. 1997. Evolution of human immunodeficiency virus type 1 in perinatally infected infants with rapid and slow progression to disease. J. Virol. 71:4694-4706.
-
(1997)
J. Virol
, vol.71
, pp. 4694-4706
-
-
Salvatori, F.1
Masiero, S.2
Giaquinto, C.3
Wade, C.M.4
Brown, A.J.5
Chieco-Bianchi, L.6
De Rossi, A.7
-
88
-
-
0031979771
-
Grossly defective nef gene sequences in a human immunodeficiency virus type 1-seropositive long-term nonprogressor
-
Salvi, R., A. R. Garbuglia, A. Di Caro, S. Pulciani, F. Montella, and A. Benedetto. 1998. Grossly defective nef gene sequences in a human immunodeficiency virus type 1-seropositive long-term nonprogressor. J. Virol. 72:3646-3657.
-
(1998)
J. Virol
, vol.72
, pp. 3646-3657
-
-
Salvi, R.1
Garbuglia, A.R.2
Di Caro, A.3
Pulciani, S.4
Montella, F.5
Benedetto, A.6
-
89
-
-
16044373004
-
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the ccr-5 chemokine receptor gene
-
Samson, M., F. Libert, B. J. Doranz, J. Rucker, C. Liesnard, C. M. Farber, S. Saragosti, C. Lapoumeroulie, J. Cognaux, C. Forceille, G. Muyldermans, C. Verhofstede, G. Burtonboy, M. Georges, T. Imai, S. Rana, Y. J. Yi, R. J. Smyth, R. G. Collman, R. W. Doms, G. Vassart, and M. Parmentier. 1996. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the ccr-5 chemokine receptor gene. Nature 382:722-725.
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
Libert, F.2
Doranz, B.J.3
Rucker, J.4
Liesnard, C.5
Farber, C.M.6
Saragosti, S.7
Lapoumeroulie, C.8
Cognaux, J.9
Forceille, C.10
Muyldermans, G.11
Verhofstede, C.12
Burtonboy, G.13
Georges, M.14
Imai, T.15
Rana, S.16
Yi, Y.J.17
Smyth, R.J.18
Collman, R.G.19
Doms, R.W.20
Vassart, G.21
Parmentier, M.22
more..
-
90
-
-
0030604911
-
Paediatric HIV infection
-
Scarlatti, G. 1996. Paediatric HIV infection. Lancet 348:863-868.
-
(1996)
Lancet
, vol.348
, pp. 863-868
-
-
Scarlatti, G.1
-
91
-
-
17444413400
-
Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism
-
Schindler, M., J. Munch, and F. Kirchhoff. 2005. Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism. J. Virol. 79:5489-5498.
-
(2005)
J. Virol
, vol.79
, pp. 5489-5498
-
-
Schindler, M.1
Munch, J.2
Kirchhoff, F.3
-
92
-
-
0141521574
-
Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles
-
Schindler, M., S. Wurfl, P. Benaroch, T. C. Greenough, R. Daniels, P. Easterbrook, M. Brenner, J. Munch, and F. Kirchhoff. 2003. Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles. J. Virol. 77:10548-10556.
-
(2003)
J. Virol
, vol.77
, pp. 10548-10556
-
-
Schindler, M.1
Wurfl, S.2
Benaroch, P.3
Greenough, T.C.4
Daniels, R.5
Easterbrook, P.6
Brenner, M.7
Munch, J.8
Kirchhoff, F.9
-
93
-
-
0024806428
-
Survival in children with perinatally acquired human immunodeficiency virus type 1 infection
-
Scott, G. B., C. Hutto, R. W. Makuch, M. T. Mastrucci, T. O'Connor, C. D. Mitchell, E. J. Trapido, and W. P. Parks. 1989. Survival in children with perinatally acquired human immunodeficiency virus type 1 infection. N. Engl. J. Med. 321:1791-1796.
-
(1989)
N. Engl. J. Med
, vol.321
, pp. 1791-1796
-
-
Scott, G.B.1
Hutto, C.2
Makuch, R.W.3
Mastrucci, M.T.4
O'Connor, T.5
Mitchell, C.D.6
Trapido, E.J.7
Parks, W.P.8
-
94
-
-
0036201092
-
Expression of simian immunodeficiency virus nef in immune cells of transgenic mice leads to a severe AIDS-like disease
-
Simard, M.-C., P. Chrobak, D. G. Kay, Z. Hanna, S. Jothy, and P. Jolicoeur. 2002. Expression of simian immunodeficiency virus nef in immune cells of transgenic mice leads to a severe AIDS-like disease. J. Virol. 76:3981-3995.
-
(2002)
J. Virol
, vol.76
, pp. 3981-3995
-
-
Simard, M.-C.1
Chrobak, P.2
Kay, D.G.3
Hanna, Z.4
Jothy, S.5
Jolicoeur, P.6
-
95
-
-
0033499148
-
HIV and SIV Nef modulate signal transduction and protein sorting in T cells
-
Skowronski, J., M. E. Greenberg, M. Lock, R. Mariani, S. Salghetti, T. Swigut, and A. J. Iafrate. 1999. HIV and SIV Nef modulate signal transduction and protein sorting in T cells. Cold Spring Harbor Symp. Quant. Biol. 64:453-463.
-
(1999)
Cold Spring Harbor Symp. Quant. Biol
, vol.64
, pp. 453-463
-
-
Skowronski, J.1
Greenberg, M.E.2
Lock, M.3
Mariani, R.4
Salghetti, S.5
Swigut, T.6
Iafrate, A.J.7
-
96
-
-
0027533215
-
Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene
-
Skowronski, J., D. Parks, and R. Mariani. 1993. Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene. EMBO J. 12:703-713.
-
(1993)
EMBO J
, vol.12
, pp. 703-713
-
-
Skowronski, J.1
Parks, D.2
Mariani, R.3
-
97
-
-
0038299654
-
HIV-1 pathogenesis
-
Stevenson, M. 2003. HIV-1 pathogenesis. Nat. Med. 9:853-860.
-
(2003)
Nat. Med
, vol.9
, pp. 853-860
-
-
Stevenson, M.1
-
98
-
-
0035834141
-
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
-
Stumptner-Cuvelette, P., S. Morchoisne, M. Dugast, S. Le Gall, G. Raposo, O. Schwartz, and P. Benaroch. 2001. HIV-1 Nef impairs MHC class II antigen presentation and surface expression. Proc. Natl. Acad. Sci. USA 98:12144-12149.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12144-12149
-
-
Stumptner-Cuvelette, P.1
Morchoisne, S.2
Dugast, M.3
Le Gall, S.4
Raposo, G.5
Schwartz, O.6
Benaroch, P.7
-
99
-
-
32444447791
-
+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate
-
+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate. J. Virol. 80:1850-1862.
-
(2006)
J. Virol
, vol.80
, pp. 1850-1862
-
-
Sun, J.1
Soos, T.2
Kewalramani, V.N.3
Osiecki, K.4
Zheng, J.H.5
Falkin, L.6
Santambrogio, L.7
Liftman, D.R.8
Goldstein, H.9
-
100
-
-
0025748151
-
Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1
-
Terwilliger, E. F., E. Langhoff, D. Gabuzda, E. Zazopoulos, and W. A. Haseltine. 1991. Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 88:10971-10975.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 10971-10975
-
-
Terwilliger, E.F.1
Langhoff, E.2
Gabuzda, D.3
Zazopoulos, E.4
Haseltine, W.A.5
-
101
-
-
0036109518
-
Inefficient enhancement of viral infectivity and CD4 downregulation by human immunodeficiency virus type 1 Nef from Japanese long-term nonprogressors
-
Tobiume, M., M. Takahoko, T. Yamada, M. Tatsumi, A. Iwamoto, and M. Matsuda. 2002. Inefficient enhancement of viral infectivity and CD4 downregulation by human immunodeficiency virus type 1 Nef from Japanese long-term nonprogressors. J. Virol. 76:5959-5965.
-
(2002)
J. Virol
, vol.76
, pp. 5959-5965
-
-
Tobiume, M.1
Takahoko, M.2
Yamada, T.3
Tatsumi, M.4
Iwamoto, A.5
Matsuda, M.6
-
102
-
-
33646373225
-
Activation of p21-activated kinase 2 and its association with Nef are conserved in murine cells but are not sufficient to induce an AIDS-like disease in CD4C/HIV transgenic mice
-
Vincent, P., E. Priceputu, D. Kay, K. Saksela, P. Jolicoeur, and Z. Hanna. 2006. Activation of p21-activated kinase 2 and its association with Nef are conserved in murine cells but are not sufficient to induce an AIDS-like disease in CD4C/HIV transgenic mice. J. Biol. Chem. 281:6940-6954.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 6940-6954
-
-
Vincent, P.1
Priceputu, E.2
Kay, D.3
Saksela, K.4
Jolicoeur, P.5
Hanna, Z.6
-
103
-
-
2342569732
-
CD4 T cells from CD4C/HIV nef transgenic mice show enhanced activation in vivo with impaired proliferation in vitro, but are dispensable for the development of a severe AIDS-like organ disease
-
Weng, X., E. Priceputu, P. Chrobak, J. Poudrier, D. G. Kay, Z. Hanna, T. W. Mak, and P. Jolicoeur. 2004. CD4 T cells from CD4C/HIV nef transgenic mice show enhanced activation in vivo with impaired proliferation in vitro, but are dispensable for the development of a severe AIDS-like organ disease. J. Virol. 78:5244-5257.
-
(2004)
J. Virol
, vol.78
, pp. 5244-5257
-
-
Weng, X.1
Priceputu, E.2
Chrobak, P.3
Poudrier, J.4
Kay, D.G.5
Hanna, Z.6
Mak, T.W.7
Jolicoeur, P.8
-
104
-
-
0027237785
-
Effect of nef alleles on replication of human immunodeficiency virus type 1
-
Zazopoulos, E., and W. A. Haseltine. 1993. Effect of nef alleles on replication of human immunodeficiency virus type 1. Virology 194:20-27.
-
(1993)
Virology
, vol.194
, pp. 20-27
-
-
Zazopoulos, E.1
Haseltine, W.A.2
|