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Volumn 79, Issue 10, 2005, Pages 6377-6391

The Nef-mediated AIDS-like disease of CD4C/human immunodeficiency virus transgenic mice is associated with increased Fas/FasL expression on T cells and T-cell death but is not prevented in Fas-, FasL-, tumor necrosis factor receptor 1-, or interleukin-1β-converting enzyme-deficient or Bcl2-expressing transgenic mice

Author keywords

[No Author keywords available]

Indexed keywords

7 AMINODACTINOMYCIN; CD4 ANTIGEN; CD8 ANTIGEN; FAS ANTIGEN; FAS LIGAND; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOCORTIN 5; NEF PROTEIN; PROPIDIUM IODIDE; PROTEIN BCL 2; TUMOR NECROSIS FACTOR RECEPTOR 1;

EID: 18144416901     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.10.6377-6391.2005     Document Type: Article
Times cited : (29)

References (98)
  • 1
    • 0031587826 scopus 로고    scopus 로고
    • Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
    • Akashi, K., M. Kondo, U. von Freeden-Jeffry, R. Murray, and I. L. Weissman. 1997. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89:1033-1041.
    • (1997) Cell , vol.89 , pp. 1033-1041
    • Akashi, K.1    Kondo, M.2    Von Freeden-Jeffry, U.3    Murray, R.4    Weissman, I.L.5
  • 2
    • 0029744038 scopus 로고    scopus 로고
    • Induction of "tissue" transglutaminase in HIV pathogenesis: Evidence for high rate of apoptosis of CD4+ T lymphocytes and accessory cells in lymphoid tissues
    • Amendola, A., M. L. Gougeon, F. Poccia, A. Bondurand, L. Fesus, and M. Piacentini. 1996. Induction of "tissue" transglutaminase in HIV pathogenesis: evidence for high rate of apoptosis of CD4+ T lymphocytes and accessory cells in lymphoid tissues. Proc. Natl. Acad. Sci. USA 93:11057-11062.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11057-11062
    • Amendola, A.1    Gougeon, M.L.2    Poccia, F.3    Bondurand, A.4    Fesus, L.5    Piacentini, M.6
  • 3
    • 0031572847 scopus 로고    scopus 로고
    • The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling
    • Arold, S., P. Franken, M. P. Strub, F. Hoh, S. Benichou, R. Benarous, and C. Dumas. 1997. The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling. Structure 5:1361-1372.
    • (1997) Structure , vol.5 , pp. 1361-1372
    • Arold, S.1    Franken, P.2    Strub, M.P.3    Hoh, F.4    Benichou, S.5    Benarous, R.6    Dumas, C.7
  • 4
    • 0031019006 scopus 로고    scopus 로고
    • Macrophage-dependent apoptosis of CD4+ T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor
    • Badley, A. D., D. Dockrell, M. Simpson, R. Schut, D. H. Lynch, P. Leibson, and C. V. Paya. 1997. Macrophage-dependent apoptosis of CD4+ T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor. J. Exp. Med. 185:55-64.
    • (1997) J. Exp. Med. , vol.185 , pp. 55-64
    • Badley, A.D.1    Dockrell, D.2    Simpson, M.3    Schut, R.4    Lynch, D.H.5    Leibson, P.6    Paya, C.V.7
  • 5
    • 0029655757 scopus 로고    scopus 로고
    • Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes
    • Badley, A. D., J. A. McElhinny, P. J. Leibson, D. H. Lynch, M. R. Alderson, and C. V. Paya. 1996. Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes. J. Virol. 70:199-206.
    • (1996) J. Virol. , vol.70 , pp. 199-206
    • Badley, A.D.1    McElhinny, J.A.2    Leibson, P.J.3    Lynch, D.H.4    Alderson, M.R.5    Paya, C.V.6
  • 6
    • 0034329318 scopus 로고    scopus 로고
    • Mechanisms of HIV-associated lymphocyte apoptosis
    • Badley, A. D., A. A, Pilon, A. Landay, and D. H. Lynch. 2000. Mechanisms of HIV-associated lymphocyte apoptosis. Blood 96:2951-2964.
    • (2000) Blood , vol.96 , pp. 2951-2964
    • Badley, A.D.1    Pilon, A.A.2    Landay, A.3    Lynch, D.H.4
  • 7
    • 0031226001 scopus 로고    scopus 로고
    • The proliferative in vivo activities of lpr double-negative T cells and the primary role of p59fyn in their activation and expansion
    • Balomenos, D., R. Rumold, and A. N. Theofilopoulos. 1997. The proliferative in vivo activities of lpr double-negative T cells and the primary role of p59fyn in their activation and expansion. J. Immunol. 159:2265-2273.
    • (1997) J. Immunol. , vol.159 , pp. 2265-2273
    • Balomenos, D.1    Rumold, R.2    Theofilopoulos, A.N.3
  • 8
    • 0029098443 scopus 로고
    • Apoptosis in human immunodeficiency virus-associated nephropathy
    • Bodi, I., A. A. Abraham, and P. L. Kimmel. 1995. Apoptosis in human immunodeficiency virus-associated nephropathy. Am. J. Kidney Dis. 26:286-291.
    • (1995) Am. J. Kidney Dis. , vol.26 , pp. 286-291
    • Bodi, I.1    Abraham, A.A.2    Kimmel, P.L.3
  • 9
    • 0029163157 scopus 로고
    • Development of a human thymic organ culture model for the study of HIV pathogenesis
    • Bonyhadi, M. L., L. Su, J. Auten, J. M. McCune, and H. Kaneshima. 1995. Development of a human thymic organ culture model for the study of HIV pathogenesis. AIDS Res. Hum. Retrovir. 11:1073-1080.
    • (1995) AIDS Res. Hum. Retrovir. , vol.11 , pp. 1073-1080
    • Bonyhadi, M.L.1    Su, L.2    Auten, J.3    McCune, J.M.4    Kaneshima, H.5
  • 10
    • 0028265466 scopus 로고
    • High expression of APO-1 (CD95) on T lymphocytes from human immunodeficiency virus-1-infected children
    • Debatin, K. M., A. Fahrig-Faissner, S. Enenkel-Stoodt, W. Kreuz, A. Benner, and P. H. Krammer. 1994. High expression of APO-1 (CD95) on T lymphocytes from human immunodeficiency virus-1-infected children. Blood 83: 3101-3103.
    • (1994) Blood , vol.83 , pp. 3101-3103
    • Debatin, K.M.1    Fahrig-Faissner, A.2    Enenkel-Stoodt, S.3    Kreuz, W.4    Benner, A.5    Krammer, P.H.6
  • 11
    • 0036493726 scopus 로고    scopus 로고
    • Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: Relation to expression of Bcl-2 and active caspase-8 and caspase-3
    • de Oliveira Pinto, L. M., S. Garcia, H. Lecoeur, C. Rapp, and M. L. Gougeon. 2002. Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: relation to expression of Bcl-2 and active caspase-8 and caspase-3. Blood 99:1666-1675.
    • (2002) Blood , vol.99 , pp. 1666-1675
    • De Oliveira Pinto, L.M.1    Garcia, S.2    Lecoeur, H.3    Rapp, C.4    Gougeon, M.L.5
  • 14
    • 0033589664 scopus 로고    scopus 로고
    • Activation-induced CD4+ T cell death in HIV-positive individuals correlates with Fas susceptibility, CD4+ T cell count, and HIV plasma viral copy number
    • Dockrell, D. H., A. D. Badley, A. Algeciras-Schimnich, M. Simpson, R. Schut, D. H. Lynch, and C. V. Paya. 1999. Activation-induced CD4+ T cell death in HIV-positive individuals correlates with Fas susceptibility, CD4+ T cell count, and HIV plasma viral copy number. AIDS Res. Hum. Retrovir. 15:1509-1518.
    • (1999) AIDS Res. Hum. Retrovir. , vol.15 , pp. 1509-1518
    • Dockrell, D.H.1    Badley, A.D.2    Algeciras-Schimnich, A.3    Simpson, M.4    Schut, R.5    Lynch, D.H.6    Paya, C.V.7
  • 16
    • 0029992895 scopus 로고    scopus 로고
    • Fas-mediated apoptosis of CD4+ and CD8+ T cells from human immunodeficiency virus-infected persons: Differential in vitro preventive effect of cytokines and protease antagonists
    • Estaquier, J., M. Tanaka, T. Suda, S. Nagata, P. Golstein, and J. C. Ameisen. 1996. Fas-mediated apoptosis of CD4+ and CD8+ T cells from human immunodeficiency virus-infected persons: differential in vitro preventive effect of cytokines and protease antagonists. Blood 87:4959-4966.
    • (1996) Blood , vol.87 , pp. 4959-4966
    • Estaquier, J.1    Tanaka, M.2    Suda, T.3    Nagata, S.4    Golstein, P.5    Ameisen, J.C.6
  • 20
    • 9044232148 scopus 로고    scopus 로고
    • The Fas receptor in HIV infection: Expression on peripheral blood lymphocytes and role in the depletion of T cells
    • Gehri, R., S. Hahn, M. Rothen, M. Steuerwald, R. Nuesch, and P. Erb. 1996. The Fas receptor in HIV infection: expression on peripheral blood lymphocytes and role in the depletion of T cells. AIDS 10:9-16.
    • (1996) AIDS , vol.10 , pp. 9-16
    • Gehri, R.1    Hahn, S.2    Rothen, M.3    Steuerwald, M.4    Nuesch, R.5    Erb, P.6
  • 21
    • 0028268517 scopus 로고
    • Chronic treatment of C3H-lpr/lpr and C3H-gld/gld mice with anti-CD8 monoclonal antibody prevents the accumulation of double negative T cells but not autoantibody production
    • Giese, T., and W. F. Davidson 1994. Chronic treatment of C3H-lpr/lpr and C3H-gld/gld mice with anti-CD8 monoclonal antibody prevents the accumulation of double negative T cells but not autoantibody production. J. Immunol. 152:2000-2010.
    • (1994) J. Immunol. , vol.152 , pp. 2000-2010
    • Giese, T.1    Davidson, W.F.2
  • 23
    • 0026517545 scopus 로고
    • Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals
    • Groux, H., G. Torpier, D. Monte, Y. Mouton, A. Capron, and J. C. Ameisen. 1992. Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals. J. Exp. Med. 175:331-340.
    • (1992) J. Exp. Med. , vol.175 , pp. 331-340
    • Groux, H.1    Torpier, G.2    Monte, D.3    Mouton, Y.4    Capron, A.5    Ameisen, J.C.6
  • 24
    • 0031964791 scopus 로고    scopus 로고
    • Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like disease
    • Hanna, Z., D. G. Kay, M. Cool, S. Jothy, N. Rebai, and P. Jolicoeur. 1998. Transgenic mice expressing human immunodeficiency virus type 1 in immune cells develop a severe AIDS-like disease. J. Virol. 72:121-132.
    • (1998) J. Virol. , vol.72 , pp. 121-132
    • Hanna, Z.1    Kay, D.G.2    Cool, M.3    Jothy, S.4    Rebai, N.5    Jolicoeur, P.6
  • 25
    • 0032538278 scopus 로고    scopus 로고
    • Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
    • Hanna, Z., D. G. Kay, N. Rebai, A. Guimond, S. Jothy, and P. Jolicoeur. 1998. Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice. Cell 95:163-175.
    • (1998) Cell , vol.95 , pp. 163-175
    • Hanna, Z.1    Kay, D.G.2    Rebai, N.3    Guimond, A.4    Jothy, S.5    Jolicoeur, P.6
  • 26
    • 0035496910 scopus 로고    scopus 로고
    • Distinct regulatory elements are required for faithful expression of human CD4 in T cells, macrophages, and dendritic cells of transgenic mice
    • Hanna, Z., N. Rebai, J. Poudrier, and P. Jolicoeur. 2001. Distinct regulatory elements are required for faithful expression of human CD4 in T cells, macrophages, and dendritic cells of transgenic mice. Blood 98:2275-2278.
    • (2001) Blood , vol.98 , pp. 2275-2278
    • Hanna, Z.1    Rebai, N.2    Poudrier, J.3    Jolicoeur, P.4
  • 29
    • 0031938303 scopus 로고    scopus 로고
    • Correlation between plasma levels of cytokines and HIV-1 RNA copy number in HIV-infected patients
    • Hittinger, G., C. Poggi, E. Delbeke, N. Profizi, and A. Lafeuillade. 1998. Correlation between plasma levels of cytokines and HIV-1 RNA copy number in HIV-infected patients. Infection 26:100-103.
    • (1998) Infection , vol.26 , pp. 100-103
    • Hittinger, G.1    Poggi, C.2    Delbeke, E.3    Profizi, N.4    Lafeuillade, A.5
  • 30
    • 0032567483 scopus 로고    scopus 로고
    • Induction of fas ligand expression by an acutely lethal simian immunodeficiency virus, SIVsmmPBj14
    • Hodge, S., F. J. Novembre, L. Whetter, H. A. Gelbard, and S. Dewhurst. 1998. Induction of fas ligand expression by an acutely lethal simian immunodeficiency virus, SIVsmmPBj14. Virology 252:354-363.
    • (1998) Virology , vol.252 , pp. 354-363
    • Hodge, S.1    Novembre, F.J.2    Whetter, L.3    Gelbard, H.A.4    Dewhurst, S.5
  • 31
    • 0031691078 scopus 로고    scopus 로고
    • Membrane and soluble forms of Fas (CD95) and Fas ligand in peripheral blood mononuclear cells and in plasma from human immunodeficiency virus-infected persons
    • Hosaka, N., N. Oyaizu, M. H. Kaplan, H. Yagita, and S. Pahwa. 1998. Membrane and soluble forms of Fas (CD95) and Fas ligand in peripheral blood mononuclear cells and in plasma from human immunodeficiency virus-infected persons. J. Infect. Dis. 178:1030-1039.
    • (1998) J. Infect. Dis. , vol.178 , pp. 1030-1039
    • Hosaka, N.1    Oyaizu, N.2    Kaplan, M.H.3    Yagita, H.4    Pahwa, S.5
  • 32
    • 0030788286 scopus 로고    scopus 로고
    • Upregulation of Fas ligand by simian immunodeficiency virus-a nef-arious mechanism of immune evasion?
    • Johnson, R. P. 1997. Upregulation of Fas ligand by simian immunodeficiency virus-a nef-arious mechanism of immune evasion? J. Exp. Med. 186:1-5.
    • (1997) J. Exp. Med. , vol.186 , pp. 1-5
    • Johnson, R.P.1
  • 33
    • 0031903406 scopus 로고    scopus 로고
    • Role of the Fas/Fas ligand apoptotic pathway in human immunodeficiency virus type 1 disease
    • Kaplan, D., and S. Sieg. 1998. Role of the Fas/Fas ligand apoptotic pathway in human immunodeficiency virus type 1 disease. J. Virol. 72:6279-6282.
    • (1998) J. Virol. , vol.72 , pp. 6279-6282
    • Kaplan, D.1    Sieg, S.2
  • 35
    • 0029048581 scopus 로고
    • Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals
    • Katsikis, P. D., E. S. Wunderlich, C. A. Smith, L. A. Herzenberg, and L. A. Herzenberg. 1995. Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J. Exp. Med. 181:2029-2036.
    • (1995) J. Exp. Med. , vol.181 , pp. 2029-2036
    • Katsikis, P.D.1    Wunderlich, E.S.2    Smith, C.A.3    Herzenberg, L.A.4    Herzenberg, L.A.5
  • 36
    • 0036313609 scopus 로고    scopus 로고
    • Cardiac disease in transgenic mice expressing human immunodeficiency virus-1 Nef in cells of the immune system
    • Kay, D. G., P. Yue, Z. Hanna, S. Jothy, E. Tremblay, and P. Jolicoeur. 2002. Cardiac disease in transgenic mice expressing human immunodeficiency virus-1 Nef in cells of the immune system. Am. J. Pathol. 161:321-335.
    • (2002) Am. J. Pathol. , vol.161 , pp. 321-335
    • Kay, D.G.1    Yue, P.2    Hanna, Z.3    Jothy, S.4    Tremblay, E.5    Jolicoeur, P.6
  • 37
    • 0034788136 scopus 로고    scopus 로고
    • Cytokines and HIV-1: Interactions and clinical implications
    • Kedzierska, K., and S. M. Crowe. 2001. Cytokines and HIV-1: interactions and clinical implications. Antivir. Chem. Chemother. 12:133-150.
    • (2001) Antivir. Chem. Chemother. , vol.12 , pp. 133-150
    • Kedzierska, K.1    Crowe, S.M.2
  • 38
    • 0033527615 scopus 로고    scopus 로고
    • Regulation of lineage commitment distinct from positive selection
    • Keefe, R., V. Dave, D. Allman, D. Wiest, and D. J. Kappes. 1999. Regulation of lineage commitment distinct from positive selection. Science 286:1149-1153.
    • (1999) Science , vol.286 , pp. 1149-1153
    • Keefe, R.1    Dave, V.2    Allman, D.3    Wiest, D.4    Kappes, D.J.5
  • 39
    • 0030785487 scopus 로고    scopus 로고
    • A major human immunodeficiency virus type 1-initiated killing pathway distinct from apoptosis
    • Kolesnitchenko, V., L. King, A. Riva, Y. Tani, S. J. Korsmeyer, and D. I. Cohen. 1997. A major human immunodeficiency virus type 1-initiated killing pathway distinct from apoptosis. J. Virol. 71:9753-9763.
    • (1997) J. Virol. , vol.71 , pp. 9753-9763
    • Kolesnitchenko, V.1    King, L.2    Riva, A.3    Tani, Y.4    Korsmeyer, S.J.5    Cohen, D.I.6
  • 40
    • 0034641898 scopus 로고    scopus 로고
    • CD95's deadly mission in the immune system
    • Krammer, P. H. 2000. CD95's deadly mission in the immune system. Nature 407:789-795.
    • (2000) Nature , vol.407 , pp. 789-795
    • Krammer, P.H.1
  • 41
    • 0028920863 scopus 로고
    • Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
    • Kuida, K., J. A. Lippke, G. Ku, M. W. Harding, D. J. Livingston, M. S. Su, and R. A. Flavell. 1995. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 267:2000-2003.
    • (1995) Science , vol.267 , pp. 2000-2003
    • Kuida, K.1    Lippke, J.A.2    Ku, G.3    Harding, M.W.4    Livingston, D.J.5    Su, M.S.6    Flavell, R.A.7
  • 42
    • 2642593019 scopus 로고    scopus 로고
    • Differential susceptibility to activation-induced apoptosis among peripheral Th1 subsets: Correlation with Bcl-2 expression and consequences for AIDS pathogenesis
    • Ledru, E., H. Lecoeur, S. Garcia, T. Debord, and M. L. Gougeon. 1998. Differential susceptibility to activation-induced apoptosis among peripheral Th1 subsets: correlation with Bcl-2 expression and consequences for AIDS pathogenesis. J. Immunol. 160:3194-3206.
    • (1998) J. Immunol. , vol.160 , pp. 3194-3206
    • Ledru, E.1    Lecoeur, H.2    Garcia, S.3    Debord, T.4    Gougeon, M.L.5
  • 43
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis-immune regulation in a dynamic and unpredictable antigenic environment
    • Lenardo, M., K. M. Chan, F. Hornung, H. McFarland, R. Siegel, J. Wang, and L. Zheng. 1999. Mature T lymphocyte apoptosis-immune regulation in a dynamic and unpredictable antigenic environment. Annu. Rev. Immunol. 17:221-253.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 221-253
    • Lenardo, M.1    Chan, K.M.2    Hornung, F.3    McFarland, H.4    Siegel, R.5    Wang, J.6    Zheng, L.7
  • 45
    • 0023275975 scopus 로고
    • Idiopathic production of interleukin-1 in acquired immune deficiency syndrome
    • Lepe-Zuniga, J. L., P. W. Mansell, and E. M. Hersh. 1987. Idiopathic production of interleukin-1 in acquired immune deficiency syndrome. J. Clin. Microbiol. 25:1695-1700.
    • (1987) J. Clin. Microbiol. , vol.25 , pp. 1695-1700
    • Lepe-Zuniga, J.L.1    Mansell, P.W.2    Hersh, E.M.3
  • 47
    • 0028984948 scopus 로고
    • Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
    • Li, P., H. Allen, S. Banerjee, S. Franklin, L. Herzog, C. Johnston, J. McDowell, M. Paskind, L. Rodman, J. Salfeld, et al. 1995. Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 80:401-411.
    • (1995) Cell , vol.80 , pp. 401-411
    • Li, P.1    Allen, H.2    Banerjee, S.3    Franklin, S.4    Herzog, L.5    Johnston, C.6    McDowell, J.7    Paskind, M.8    Rodman, L.9    Salfeld, J.10
  • 48
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley, R. M., N. Killeen, and M. J. Lenardo. 2001. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104:487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 50
    • 0028898599 scopus 로고
    • Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I
    • Maldonado, M. A., R. A. Eisenberg, E. Roper, P. L. Cohen, and B. L. Kotzin. 1995. Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I. J. Exp. Med. 181:641-648.
    • (1995) J. Exp. Med. , vol.181 , pp. 641-648
    • Maldonado, M.A.1    Eisenberg, R.A.2    Roper, E.3    Cohen, P.L.4    Kotzin, B.L.5
  • 51
    • 0031587875 scopus 로고    scopus 로고
    • Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice
    • Maraskovsky, E., L. A. O'Reilly, M. Teepe, L. M. Corcoran, J. J. Peschon, and A. Strasser. 1997. Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice. Cell 89: 1011-1019.
    • (1997) Cell , vol.89 , pp. 1011-1019
    • Maraskovsky, E.1    O'Reilly, L.A.2    Teepe, M.3    Corcoran, L.M.4    Peschon, J.J.5    Strasser, A.6
  • 52
    • 0026333671 scopus 로고
    • Cytokines and HIV infection: Is AIDS a tumor necrosis factor disease?
    • Matsuyama, T., N. Kobayashi, and N. Yamamoto. 1991. Cytokines and HIV infection: is AIDS a tumor necrosis factor disease? AIDS 5:1405-1417.
    • (1991) AIDS , vol.5 , pp. 1405-1417
    • Matsuyama, T.1    Kobayashi, N.2    Yamamoto, N.3
  • 53
  • 54
    • 0032529216 scopus 로고    scopus 로고
    • TCR ligation on CD8+ T cells creates double-negative cells in vivo
    • Mehal, W. Z., and I. N. Crispe. 1998. TCR ligation on CD8+ T cells creates double-negative cells in vivo. J. Immunol. 161:1686-1693.
    • (1998) J. Immunol. , vol.161 , pp. 1686-1693
    • Mehal, W.Z.1    Crispe, I.N.2
  • 55
    • 0024415190 scopus 로고
    • Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor
    • Merrill, J. E., Y. Koyanagi, and I. S. Chen. 1989. Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor. J. Virol. 63:4404-4408.
    • (1989) J. Virol. , vol.63 , pp. 4404-4408
    • Merrill, J.E.1    Koyanagi, Y.2    Chen, I.S.3
  • 57
    • 0028985494 scopus 로고
    • Decreased CD4-CD8- TCR-alpha beta + cells in lpr/lpr mice lacking beta 2-microglobulin
    • Mixter, P. F., J. Q. Russell, F. H. Durie, and R. C. Budd. 1995. Decreased CD4-CD8- TCR-alpha beta + cells in lpr/lpr mice lacking beta 2-microglobulin. J. Immunol. 154:2063-2074.
    • (1995) J. Immunol. , vol.154 , pp. 2063-2074
    • Mixter, P.F.1    Russell, J.Q.2    Durie, F.H.3    Budd, R.C.4
  • 58
    • 0042629341 scopus 로고    scopus 로고
    • Extensive apoptosis in lymphoid organs during primary SIV infection predicts rapid progression towards AIDS
    • Monceaux, V., J. Estaquier, M. Fevrier, M. C. Cumont, Y. Riviere, A. M. Aubertin, J. C. Ameisen, and B. Hurtrel. 2003. Extensive apoptosis in lymphoid organs during primary SIV infection predicts rapid progression towards AIDS. AIDS 17:1585-1596.
    • (2003) AIDS , vol.17 , pp. 1585-1596
    • Monceaux, V.1    Estaquier, J.2    Fevrier, M.3    Cumont, M.C.4    Riviere, Y.5    Aubertin, A.M.6    Ameisen, J.C.7    Hurtrel, B.8
  • 59
    • 0034598365 scopus 로고    scopus 로고
    • Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy
    • Newton, K., and A. Strasser. 2000. Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy. J. Exp. Med. 191:195-200.
    • (2000) J. Exp. Med. , vol.191 , pp. 195-200
    • Newton, K.1    Strasser, A.2
  • 60
    • 0030782222 scopus 로고    scopus 로고
    • HIV-induced apoptosis of activated primary CD4+ T lymphocytes is not mediated by Fas-Fas ligand
    • Noraz, N., J. Gozlan, J. Corbeil, T. Brunner, and S. A. Spector. 1997. HIV-induced apoptosis of activated primary CD4+ T lymphocytes is not mediated by Fas-Fas ligand. AIDS 11:1671-1680.
    • (1997) AIDS , vol.11 , pp. 1671-1680
    • Noraz, N.1    Gozlan, J.2    Corbeil, J.3    Brunner, T.4    Spector, S.A.5
  • 61
    • 0032933836 scopus 로고    scopus 로고
    • Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: Evidence for a role of the envelope
    • Ohagen, A., S. Ghosh, J. He, K. Huang, Y. Chen, M. Yuan, R. Osathanondh, S. Gartner, B. Shi, G. Shaw, and D. Gabuzda. 1999. Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: evidence for a role of the envelope. J. Virol. 73:897-906.
    • (1999) J. Virol. , vol.73 , pp. 897-906
    • Ohagen, A.1    Ghosh, S.2    He, J.3    Huang, K.4    Chen, Y.5    Yuan, M.6    Osathanondh, R.7    Gartner, S.8    Shi, B.9    Shaw, G.10    Gabuzda, D.11
  • 62
    • 0028985378 scopus 로고
    • Reduced development of CD4-8-B220+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules
    • Ohteki, T., M. Iwamoto, S. Izui, and H. R. MacDonald. 1995. Reduced development of CD4-8-B220+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules. Eur. J. Immunol. 25:37-41.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 37-41
    • Ohteki, T.1    Iwamoto, M.2    Izui, S.3    MacDonald, H.R.4
  • 63
    • 9544230790 scopus 로고    scopus 로고
    • Effects of human immunodeficiency virus type 1 infection on programmed cell death in the presence or absence of Bcl-2
    • Park, I. W., E. Kondo, L. Bergeron, J. Park, and J. Sodroski. 1996. Effects of human immunodeficiency virus type 1 infection on programmed cell death in the presence or absence of Bcl-2. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 12:321-328.
    • (1996) J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. , vol.12 , pp. 321-328
    • Park, I.W.1    Kondo, E.2    Bergeron, L.3    Park, J.4    Sodroski, J.5
  • 65
    • 0029065185 scopus 로고
    • Evidence of apoptotic cell death in HIV encephalitis
    • Petito, C. K., and B. Roberts. 1995. Evidence of apoptotic cell death in HIV encephalitis. Am. J. Pathol. 146:1121-1130.
    • (1995) Am. J. Pathol. , vol.146 , pp. 1121-1130
    • Petito, C.K.1    Roberts, B.2
  • 66
  • 67
    • 0034878242 scopus 로고    scopus 로고
    • The AIDS disease of CD4C/HIV transgenic mice shows impaired germinal centers and autoantibodies and develops in the absence of IFN-γ and IL-6
    • Poudrier, J., X. Weng, D. G. Kay, G. Paré, E. L. Calvo, Z. Hanna, M. H. Kosco-Vilbois, and P. Jolicoeur. 2001. The AIDS disease of CD4C/HIV transgenic mice shows impaired germinal centers and autoantibodies and develops in the absence of IFN-γ and IL-6. Immunity 15:173-185.
    • (2001) Immunity , vol.15 , pp. 173-185
    • Poudrier, J.1    Weng, X.2    Kay, D.G.3    Paré, G.4    Calvo, E.L.5    Hanna, Z.6    Kosco-Vilbois, M.H.7    Jolicoeur, P.8
  • 69
    • 0034134113 scopus 로고    scopus 로고
    • Interactions of HIV-1 Nef with cellular signal transducing proteins
    • Renkema, G. H., and K. Saksela. 2000. Interactions of HIV-1 Nef with cellular signal transducing proteins. Front. Biosci. 5:D268-D283.
    • (2000) Front. Biosci. , vol.5
    • Renkema, G.H.1    Saksela, K.2
  • 70
    • 0029841022 scopus 로고    scopus 로고
    • Plasma levels of soluble CD30, tumour necrosis factor (TNF)-alpha and TNF receptors during primary HIV-1 infection: Correlation with HIV-1 RNA and the clinical outcome
    • Rizzardi, G. P., W. Barcellini, G. Tambussi, F. Lillo, M. Malnati, L. Perrin, and A. Lazzarin. 1996. Plasma levels of soluble CD30, tumour necrosis factor (TNF)-alpha and TNF receptors during primary HIV-1 infection: correlation with HIV-1 RNA and the clinical outcome. AIDS 10:F45-F50.
    • (1996) AIDS , vol.10
    • Rizzardi, G.P.1    Barcellini, W.2    Tambussi, G.3    Lillo, F.4    Malnati, M.5    Perrin, L.6    Lazzarin, A.7
  • 72
    • 0024512945 scopus 로고
    • Purified blood monocytes from HIV 1-infected patients produce high levels of TNF alpha and IL-1
    • Roux-Lombard, P., C. Modoux, A. Cruchaud, and J. M. Dayer. 1989. Purified blood monocytes from HIV 1-infected patients produce high levels of TNF alpha and IL-1. Clin. Immunol. Immunopathol. 50:374-384.
    • (1989) Clin. Immunol. Immunopathol. , vol.50 , pp. 374-384
    • Roux-Lombard, P.1    Modoux, C.2    Cruchaud, A.3    Dayer, J.M.4
  • 73
    • 0031585551 scopus 로고    scopus 로고
    • Apoptosis of CD4+ and CD19+ cells during human immunodeficiency virus type 1 infection-correlation with clinical progression, viral load, and loss of humoral immunity
    • Samuelsson, A., C. Brostrom, N. van Dijk, A. Sonnerborg, and F. Chiodi. 1997. Apoptosis of CD4+ and CD19+ cells during human immunodeficiency virus type 1 infection-correlation with clinical progression, viral load, and loss of humoral immunity. Virology 238:180-188.
    • (1997) Virology , vol.238 , pp. 180-188
    • Samuelsson, A.1    Brostrom, C.2    Van Dijk, N.3    Sonnerborg, A.4    Chiodi, F.5
  • 74
    • 0025751550 scopus 로고
    • bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • Sentman, C. L., J. R. Shutter, D. Hockenbery, O. Kanagawa, and S. J. Korsmeyer. 1991. bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67:879-888.
    • (1991) Cell , vol.67 , pp. 879-888
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 75
    • 0032212941 scopus 로고    scopus 로고
    • HIV-induced immunopathogenesis
    • Shearer, G. M. 1998. HIV-induced immunopathogenesis. Immunity 9:587-593.
    • (1998) Immunity , vol.9 , pp. 587-593
    • Shearer, G.M.1
  • 78
    • 0036533386 scopus 로고    scopus 로고
    • New perspectives on a developmental dilemma: The kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision
    • Singer, A. 2002. New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision. Curr. Opin. Immunol. 14:207-215.
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 207-215
    • Singer, A.1
  • 79
    • 0028485743 scopus 로고
    • The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
    • Singer, G. G., and A. K. Abbas. 1994. The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1:365-371.
    • (1994) Immunity , vol.1 , pp. 365-371
    • Singer, G.G.1    Abbas, A.K.2
  • 80
    • 0033179343 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 protease inhibitor modulates activation of peripheral blood CD4(+) T cells and decreases their susceptibility to apoptosis in vitro and in vivo
    • Sloand, E. M., P. N. Kumar, S. Kim, A. Chaudhuri, F. F. Weichold, and N. S. Young. 1999. Human immunodeficiency virus type 1 protease inhibitor modulates activation of peripheral blood CD4(+) T cells and decreases their susceptibility to apoptosis in vitro and in vivo. Blood 94:1021-1027.
    • (1999) Blood , vol.94 , pp. 1021-1027
    • Sloand, E.M.1    Kumar, P.N.2    Kim, S.3    Chaudhuri, A.4    Weichold, F.F.5    Young, N.S.6
  • 82
    • 0031049287 scopus 로고    scopus 로고
    • Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: Effect on CD44-lymphocyte depletion and human immunodeficiency virus replication
    • Sloand, E. M., N. S. Young, P. Kumar, F. F. Weichold, T. Sato, and J. P. Maciejewski. 1997. Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: effect on CD44-lymphocyte depletion and human immunodeficiency virus replication. Blood 89:1357-1363.
    • (1997) Blood , vol.89 , pp. 1357-1363
    • Sloand, E.M.1    Young, N.S.2    Kumar, P.3    Weichold, F.F.4    Sato, T.5    Maciejewski, J.P.6
  • 83
    • 0030641487 scopus 로고    scopus 로고
    • IL-1 beta convertase (ICE) does not play a requisite role in apoptosis induced in T lymphoblasts by Fas-dependent or Fas-independent CTL effector mechanisms
    • Smith, D. J., M. J. McGuire, M. J. Tocci, and D. L. Thiele. 1997. IL-1 beta convertase (ICE) does not play a requisite role in apoptosis induced in T lymphoblasts by Fas-dependent or Fas-independent CTL effector mechanisms. J. Immunol. 158:163-170.
    • (1997) J. Immunol. , vol.158 , pp. 163-170
    • Smith, D.J.1    McGuire, M.J.2    Tocci, M.J.3    Thiele, D.L.4
  • 84
    • 0028379479 scopus 로고
    • MRL-lpr/lpr disease: Theories meet Fas
    • Steinberg, A. D. 1994. MRL-lpr/lpr disease: theories meet Fas. Semin. Immunol. 6:55-69.
    • (1994) Semin. Immunol. , vol.6 , pp. 55-69
    • Steinberg, A.D.1
  • 85
    • 0018935423 scopus 로고
    • Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice
    • Steinberg, A. D., J. B. Roths, E. D. Murphy, R. T. Steinberg, and E. S. Raveche. 1980. Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice. J. Immunol. 125:871-873.
    • (1980) J. Immunol. , vol.125 , pp. 871-873
    • Steinberg, A.D.1    Roths, J.B.2    Murphy, E.D.3    Steinberg, R.T.4    Raveche, E.S.5
  • 86
    • 0025786164 scopus 로고
    • bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
    • Strasser, A., A. W. Harris, and S. Cory. 1991. bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 67:889-899.
    • (1991) Cell , vol.67 , pp. 889-899
    • Strasser, A.1    Harris, A.W.2    Cory, S.3
  • 87
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser, A., A. W. Harris, D. C. Huang, P. H. Krummer, and S. Cory. 1995. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J. 14:6136-6147.
    • (1995) EMBO J. , vol.14 , pp. 6136-6147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.3    Krummer, P.H.4    Cory, S.5
  • 88
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
    • Takahashi, T., M. Tanaka, C. I. Brannan, N. A. Jenkins, N. G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76:969-976.
    • (1994) Cell , vol.76 , pp. 969-976
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.I.3    Jenkins, N.A.4    Copeland, N.G.5    Suda, T.6    Nagata, S.7
  • 89
    • 0031014972 scopus 로고    scopus 로고
    • Cytokine pattern in relation to disease progression in human immunodeficiency virus-infected children
    • Than, S., R. Hu, N. Oyaizu, J. Romano, X. Wang, S. Sheikh, and S. Pahwa. 1997. Cytokine pattern in relation to disease progression in human immunodeficiency virus-infected children. J. Infect. Dis. 175:47-56.
    • (1997) J. Infect. Dis. , vol.175 , pp. 47-56
    • Than, S.1    Hu, R.2    Oyaizu, N.3    Romano, J.4    Wang, X.5    Sheikh, S.6    Pahwa, S.7
  • 91
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga, R., C. I. Brannan, N. G. Copeland, N. A. Jenkins, and S. Nagata. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314-317.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 92
    • 2342569732 scopus 로고    scopus 로고
    • Nef transgenic mice show enhanced activation in vivo with impaired proliferation in vitro but are dispensable for the development of a severe AIDS-like organ disease
    • Nef transgenic mice show enhanced activation in vivo with impaired proliferation in vitro but are dispensable for the development of a severe AIDS-like organ disease. J. Virol. 78:5244-5257.
    • (2004) J. Virol. , vol.78 , pp. 5244-5257
    • Weng, X.1    Priceputu, E.2    Chrobak, P.3    Poudrier, J.4    Kay, D.G.5    Hanna, Z.6    Mak, T.W.7    Jolicoeur, P.8
  • 96
    • 0028111877 scopus 로고
    • Tumor necrosis factor alpha and soluble tumor necrosis factor receptors in individuals with human immunodeficiency virus infection
    • Zangerle, R., H. Gallati, M. Sarcletti, H. Wachter, and D. Fuchs. 1994. Tumor necrosis factor alpha and soluble tumor necrosis factor receptors in individuals with human immunodeficiency virus infection. Immunol. Lett. 41:229-234.
    • (1994) Immunol. Lett. , vol.41 , pp. 229-234
    • Zangerle, R.1    Gallati, H.2    Sarcletti, M.3    Wachter, H.4    Fuchs, D.5
  • 97
    • 0032959989 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Nef protein sensitizes CD4(+) T lymphoid cells to apoptosis via functional upregulation of the CD95/CD95 ligand pathway
    • Zauli, G., D. Gibellini, P. Secchiero, H. Dutartre, D. Olive, S. Capitani, and Y. Collette. 1999. Human immunodeficiency virus type 1 Nef protein sensitizes CD4(+) T lymphoid cells to apoptosis via functional upregulation of the CD95/CD95 ligand pathway. Blood 93:1000-1010.
    • (1999) Blood , vol.93 , pp. 1000-1010
    • Zauli, G.1    Gibellini, D.2    Secchiero, P.3    Dutartre, H.4    Olive, D.5    Capitani, S.6    Collette, Y.7
  • 98
    • 0031014644 scopus 로고    scopus 로고
    • Early cytokine and chemokine gene expression in lymph nodes of macaques infected with simian immunodeficiency virus is predictive of disease outcome and vaccine efficacy
    • Zou, W., A. A. Lackner, M. Simon, I. Durand-Gasselin, P. Galanaud, R. C. Desrosiers, and D. Emilie. 1997. Early cytokine and chemokine gene expression in lymph nodes of macaques infected with simian immunodeficiency virus is predictive of disease outcome and vaccine efficacy. J. Virol. 71:1227-1236.
    • (1997) J. Virol. , vol.71 , pp. 1227-1236
    • Zou, W.1    Lackner, A.A.2    Simon, M.3    Durand-Gasselin, I.4    Galanaud, P.5    Desrosiers, R.C.6    Emilie, D.7


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