A key role for the microglial NADPH oxidase in APP-dependent killing of neurons

Neurobiology of Aging

Volumn 27, Issue 11, 2006, Pages 1577-1587

  Qin, Bin ^a   Cartier, Laetitia ^a   Dubois Dauphin, Michel ^a   Li, Bin ^a   Serrander, Lena ^a   Krause, Karl Heinz ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Alzheimers disease; Amyloid precursor protein; Microglia; NADPH oxidase; Neuroblastoma cells; NOX2

Indexed keywords

AMYLOID PRECURSOR PROTEIN; DIPHENYLIODONIUM SALT; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL CYCLE; CELL KILLING; CELL STRUCTURE; COCULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; GROWTH RATE; HUMAN; HUMAN CELL; MACROPHAGE; MICROGLIA; MOUSE; MUTATION; NERVE CELL NECROSIS; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANTIOXIDANTS; ASCORBIC ACID; BLOTTING, WESTERN; CELL COUNT; CELL CULTURE TECHNIQUES; CELL DEATH; CELL LINE, TUMOR; ENZYME INHIBITORS; HUMANS; MACROPHAGES; MICROGLIA; MICROSCOPY, FLUORESCENCE; MUTATION; NADPH OXIDASE; NEURONS; ONIUM COMPOUNDS; REACTIVE OXYGEN SPECIES; RECEPTORS, CELL SURFACE; TRANSDUCTION, GENETIC; VITAMIN E;

EID: 33748454440     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2005.09.036     Document Type: Article

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