Carboxyl-terminal fragment of Alzheimer's APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity

FASEB Journal

Volumn 14, Issue 11, 2000, Pages 1508-1517

  Kim, H S ^a   Cheol Hyoung Park, ^a   Seok Ho Cha, ^a   Lee, J H ^a   Lee, S ^a   Kim, Y ^a   Rah, J C ^a   Jeong, S J ^a   Suh, Y H ^a  

^a Seoul National University   (South Korea)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Glutamate; Intracellular free calcium concentration; sheet conformation

Indexed keywords

AMINO ACID; AMYLOID PRECURSOR PROTEIN; CALCIUM; CHOLESTEROL; DIZOCILPINE; NIFEDIPINE; TRIFLUOROETHANOL; VERAPAMIL;

ALZHEIMER DISEASE; AMNESIA; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CARBOXY TERMINAL SEQUENCE; EMBRYO; GLIOBLASTOMA; HIPPOCAMPUS; HUMAN; HUMAN CELL; LONG TERM POTENTIATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; RAT;

EID: 0033898887     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.99-0809com     Document Type: Article

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