-
1
-
-
67650238578
-
-
in by T L Lemke & D A Williams, 5th edn (Lippincott Williams & Wilkins, USA)
-
Lemke T L, in Foye's Principles of Medicinal Chemistry by T L Lemke & D A Williams, 5th edn (Lippincott Williams & Wilkins, USA) 2002, 904-906.
-
Foye's Principles of Medicinal Chemistry
, vol.2002
, pp. 904-906
-
-
Lemke, T.L.1
-
3
-
-
33947200513
-
-
www.who.org
-
-
-
-
5
-
-
0038757566
-
Targeting tuberculosis and malaria through inhibition of enoyl reductase
-
Kuo M R, Morbidoni H R, Alland D, Sneddon S F, Gourlie B B, Staveski M M, Leonard M, Gregory J S, Janjigian A D, Lee C, Musser J M, Kreiswirth B, Iwamoto H, Perozzo R, Jacobs W R, Sacchettini J C & Fidock D A, Targeting tuberculosis and malaria through inhibition of enoyl reductase, J Biol Chem, 278 (2003) 20851-20859.
-
(2003)
J Biol Chem
, vol.278
, pp. 20851-20859
-
-
Kuo, M.R.1
Morbidoni, H.R.2
Alland, D.3
Sneddon, S.F.4
Gourlie, B.B.5
Staveski, M.M.6
Leonard, M.7
Gregory, J.S.8
Janjigian, A.D.9
Lee, C.10
Musser, J.M.11
Kreiswirth, B.12
Iwamoto, H.13
Perozzo, R.14
Jacobs, W.R.15
Sacchettini, J.C.16
Fidock, D.A.17
-
6
-
-
0030298489
-
Enzymatic synthesis of UDP-galactofuranose and an assay for UDP-galactopyranose mutase based on high-performance liquid chromatography
-
Lee R, Monsey D, Weston A, Duncan K, Rithner C & McNeil M, Enzymatic synthesis of UDP-galactofuranose and an assay for UDP-galactopyranose mutase based on high-performance liquid chromatography, Anal Biochem, 242 (1996) 1-7.
-
(1996)
Anal Biochem
, vol.242
, pp. 1-7
-
-
Lee, R.1
Monsey, D.2
Weston, A.3
Duncan, K.4
Rithner, C.5
McNeil, M.6
-
7
-
-
0031444647
-
Mycobacterial arabinan biosynthesis: The use of synthetic arabinoside acceptors in the development of an arabinosyl transfer assay
-
Lee R E, Brennan P J &Besra G S, Mycobacterial arabinan biosynthesis: The use of synthetic arabinoside acceptors in the development of an arabinosyl transfer assay, Glycobiology, 7 (1997) 1121-1128.
-
(1997)
Glycobiology
, vol.7
, pp. 1121-1128
-
-
Lee, R.E.1
Brennan, P.J.2
Besra, G.S.3
-
8
-
-
0030950127
-
Determination of the pathway for rhamnose biosynthesis in mycobacteria: Cloning, sequencing and expression of the Mycobacterium tuberculosis gene encoding alpha-D-glucose-1-phosphate thymidylyltransferase
-
Ma Y, Mills J A, Belisle J T, Vissa V, Howell M, Bowlin K, Scherman M S & McNeil M, Determination of the pathway for rhamnose biosynthesis in mycobacteria: Cloning, sequencing and expression of the Mycobacterium tuberculosis gene encoding alpha-D-glucose-1-phosphate thymidylyltransferase, Microbiology, 143 (1997) 937-945.
-
(1997)
Microbiology
, vol.143
, pp. 937-945
-
-
Ma, Y.1
Mills, J.A.2
Belisle, J.T.3
Vissa, V.4
Howell, M.5
Bowlin, K.6
Scherman, M.S.7
McNeil, M.8
-
9
-
-
0030029877
-
Galactofuranose biosynthesis in Escherichia coli K-12: Identification and cloning of UDP-galactopyranose mutase
-
Nassau P M, Martin S L, Brown R E, Weston A, Honsey D, McNeil M R & Duncan K, Galactofuranose biosynthesis in Escherichia coli K-12: Identification and cloning of UDP-galactopyranose mutase, J Bacteriol, 178 (1996) 1047-1052.
-
(1996)
J Bacteriol
, vol.178
, pp. 1047-1052
-
-
Nassau, P.M.1
Martin, S.L.2
Brown, R.E.3
Weston, A.4
Honsey, D.5
McNeil, M.R.6
Duncan, K.7
-
10
-
-
12844278679
-
Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis
-
Takayama K, Wang C & Besra G S, Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis, Clin Microbiol Rev, 18 (2005) 81-101.
-
(2005)
Clin Microbiol Rev
, vol.18
, pp. 81-101
-
-
Takayama, K.1
Wang, C.2
Besra, G.S.3
-
11
-
-
33947246829
-
-
http://www.chemsoc.org/chembytes/ezine/1998/evans.htm
-
-
-
-
12
-
-
33947242115
-
-
in by M E Wolff, 5th edn (John-Wiley and sons Inc., USA)
-
Sensi P & Grassi C G, in Berger's Medicinal Chemistry and Drug Discovery by M E Wolff, 5th edn (John-Wiley and sons Inc., USA) 1996, 576-635.
-
Berger's Medicinal Chemistry and Drug Discovery
, vol.1996
, pp. 576-635
-
-
Sensi, P.1
Grassi, C.G.2
-
14
-
-
33947284688
-
-
in by E T Harfindal & D R Gourley, 7th edn (Lippincott Williams & Wilkins, USA)
-
Zeind C S, Gourley G K & Chandler-Toufieli D M, in Textbook of Therapeutics, Drug and Disease Management, by E T Harfindal & D R Gourley, 7th edn (Lippincott Williams & Wilkins, USA) 2004, 1427-1450.
-
Textbook of Therapeutics, Drug and Disease Management
, vol.2004
, pp. 1427-1450
-
-
Zeind, C.S.1
Gourley, G.K.2
Chandler-Toufieli, D.M.3
-
15
-
-
33947224338
-
Attack on the scourge of tuberculosis: Patented drug targets
-
Vohra R, Gupta M, Chaturvedi R & Singh Y, Attack on the scourge of tuberculosis: patented drug targets, Recent Patents on Anti-Infective Drug Discovery, 1 (2006) 95-106.
-
(2006)
Recent Patents on Anti-Infective Drug Discovery
, vol.1
, pp. 95-106
-
-
Vohra, R.1
Gupta, M.2
Chaturvedi, R.3
Singh, Y.4
-
16
-
-
0031879709
-
In vitro and in vivo activities of moxifloxacin and clinafloxacin against Mycobacterium tuberculosis
-
Ji B, Lounis N, Maslo C, Truffot-Pernot C, Bonnafous P & Grosset J, In vitro and in vivo activities of moxifloxacin and clinafloxacin against Mycobacterium tuberculosis, Antimicrob Ag Chemother, 42 (1998) 2066-2069.
-
(1998)
Antimicrob Ag Chemother
, vol.42
, pp. 2066-2069
-
-
Ji, B.1
Lounis, N.2
Maslo, C.3
Truffot-Pernot, C.4
Bonnafous, P.5
Grosset, J.6
-
17
-
-
0032910406
-
Moxifloxacin (BAY12-8039), a new 8-methoxyquinolone is active in a mouse model of tuberculosis
-
Miyazaki E, Miyazaki M, Chen J M, Chaisson R E & Bishai W R, Moxifloxacin (BAY12-8039), a new 8-methoxyquinolone is active in a mouse model of tuberculosis, Antimicrob Ag Chemother, 43 (1999) 85-89.
-
(1999)
Antimicrob Ag Chemother
, vol.43
, pp. 85-89
-
-
Miyazaki, E.1
Miyazaki, M.2
Chen, J.M.3
Chaisson, R.E.4
Bishai, W.R.5
-
18
-
-
0032729635
-
Pharmacokinetics of a once-daily oral dose of moxifloxacin (Bay 12-8039), a new enantiomerically pure 8-methoxy quinolone
-
Sullivan J T, Woodruff M, Lettieri J, Agarwal V, Krol G J, Leese P T, Watson S & Heller A H, Pharmacokinetics of a once-daily oral dose of moxifloxacin (Bay 12-8039), a new enantiomerically pure 8-methoxy quinolone, Antimicrob Ag Chemother, 43 (1999) 2793-2797.
-
(1999)
Antimicrob Ag Chemother
, vol.43
, pp. 2793-2797
-
-
Sullivan, J.T.1
Woodruff, M.2
Lettieri, J.3
Agarwal, V.4
Krol, G.J.5
Leese, P.T.6
Watson, S.7
Heller, A.H.8
-
19
-
-
0029100035
-
Antimicrobial activity of CS-940, a new trifluorinated quinolone
-
Biedenbach D J, Sutton L D & Jones R N, Antimicrobial activity of CS-940, a new trifluorinated quinolone, Antimicrob Ag Chemother, 39 (1995) 2325-2330.
-
(1995)
Antimicrob Ag Chemother
, vol.39
, pp. 2325-2330
-
-
Biedenbach, D.J.1
Sutton, L.D.2
Jones, R.N.3
-
20
-
-
0033011810
-
Fluoroquinolone action against clinical isolates of Mycobacterium tuberculosis: Effects of a C-8 methoxyl Group on survival in liquid media and in human macrophages
-
Zhao B Y, Pine R, Domagala J & Drlica K, Fluoroquinolone action against clinical isolates of Mycobacterium tuberculosis: Effects of a C-8 methoxyl Group on survival in liquid media and in human macrophages, Antimicrob Ag Chemother, 43 (1999) 661-666.
-
(1999)
Antimicrob Ag Chemother
, vol.43
, pp. 661-666
-
-
Zhao, B.Y.1
Pine, R.2
Domagala, J.3
Drlica, K.4
-
21
-
-
0032881134
-
Dual inhibitory activity of sitafloxacin(DU-6859a) against DNA gyrase and topoisomerase IV of Streptococcus pneumoniae
-
Onodera Y, Uchida Y, Tanaka M & Sato K, Dual inhibitory activity of sitafloxacin(DU-6859a) against DNA gyrase and topoisomerase IV of Streptococcus pneumoniae, J Antimicrob Chemother, 44 (1999) 533-536.
-
(1999)
J Antimicrob Chemother
, vol.44
, pp. 533-536
-
-
Onodera, Y.1
Uchida, Y.2
Tanaka, M.3
Sato, K.4
-
22
-
-
0042864697
-
Recent advances in research on antituberculars
-
Roy B N, Karnik M A & Sankaran R, Recent advances in research on antituberculars, J Ind Chem Soc, 79 (2002) 320-335.
-
(2002)
J Ind Chem Soc
, vol.79
, pp. 320-335
-
-
Roy, B.N.1
Karnik, M.A.2
Sankaran, R.3
-
23
-
-
0042515174
-
Synthesis, and antimycobacterial and cytotoxic evaluation of certain fluoroquinolone derivatives
-
Chem Abstr, 140 (2004) 16634
-
Sheu J Y, Chen Y L, Tzeng C C, Hsu S L, Fang K C & Wang T C, Synthesis, and antimycobacterial and cytotoxic evaluation of certain fluoroquinolone derivatives, Helv Chem Acta(Eng), 86 (2003) 2481-2489; Chem Abstr, 140 (2004) 16634.
-
(2003)
Helv Chem Acta(Eng)
, vol.86
, pp. 2481-2489
-
-
Sheu, J.Y.1
Chen, Y.L.2
Tzeng, C.C.3
Hsu, S.L.4
Fang, K.C.5
Wang, T.C.6
-
24
-
-
0034026489
-
Antimicrobial activities of mefloquine and a series of related compounds
-
Kunin C M & Ellis W Y, Antimicrobial activities of mefloquine and a series of related compounds, Antimicrob Ag Chemother, 44 (2000) 848-852.
-
(2000)
Antimicrob Ag Chemother
, vol.44
, pp. 848-852
-
-
Kunin, C.M.1
Ellis, W.Y.2
-
25
-
-
33947262289
-
Poster 999
-
presented at the Toronto, Ontario, Canada, 17 - 20 September Derwent World Drug Alert abstract WD-2000-013271
-
Inderlied C B, Bermudez L, Ellis W Y, Aralar P A, Kolonoski P & Petrofsky M, Poster 999, presented at the 40th Interscience Conf on Antimicrobial Agents and Chemotherapy, Toronto, Ontario, Canada, 17 - 20 September, 2000,. Derwent World Drug Alert abstract WD-2000-013271.
-
(2000)
40th Interscience Conf on Antimicrobial Agents and Chemotherapy
-
-
Inderlied, C.B.1
Bermudez, L.2
Ellis, W.Y.3
Aralar, P.A.4
Kolonoski, P.5
Petrofsky, M.6
-
26
-
-
0036661719
-
Synthesis of novel 3-N-[(substitutedaryl/heterotryl)methylene]- imino-2-methyl-5-thienyl-thieno[2,3-d]pyrimidine4-(3H)-ones as possible antimicrobial agents
-
Chambhare R V, Bobade A S & Khasde B G, Synthesis of novel 3-N-[(substitutedaryl/heterotryl)methylene]- imino-2-methyl-5-thienyl-thieno[2,3-d]pyrimidine4-(3H)-ones as possible antimicrobial agents, Ind J Het Chem, 12 (2002) 67-68.
-
(2002)
Ind J Het Chem
, vol.12
, pp. 67-68
-
-
Chambhare, R.V.1
Bobade, A.S.2
Khasde, B.G.3
-
27
-
-
0037196950
-
Synthesis and antituberculous activity of n-mannich bases of 3-[4-(4-chlorophenyl)-6-(4-methylphenyl)pyrimidin-2-yl]iminoisatin derivatives
-
Chem Abstr, 138 (2003) 89754
-
Sriram D, Yogeeswari P, Pandeya S N & Ananthan S, Synthesis and antituberculous activity of n-mannich bases of 3-[4-(4-chlorophenyl)-6-(4-methylphenyl)pyrimidin-2-yl]iminoisatin derivatives, Scientia Pharmaceutica (Eng), 70 (2002) 39-48; Chem Abstr, 138 (2003) 89754.
-
(2002)
Scientia Pharmaceutica (Eng)
, vol.70
, pp. 39-48
-
-
Sriram, D.1
Yogeeswari, P.2
Pandeya, S.N.3
Ananthan, S.4
-
28
-
-
0042284453
-
3′-C-Branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase
-
Vanheusden V, Munier-Lehmann H, Busson R, Froeyen M, Dugue L, Heyerick A, Keukeleire D D, Pochet S, Busson R, Herdiwijn P & Calenbergh S V, 3′-C-Branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase, J Med Chem, 46 (2003) 3811-3821.
-
(2003)
J Med Chem
, vol.46
, pp. 3811-3821
-
-
Vanheusden, V.1
Munier-Lehmann, H.2
Busson, R.3
Froeyen, M.4
Dugue, L.5
Heyerick, A.6
Keukeleire, D.D.7
Pochet, S.8
Busson, R.9
Herdiwijn, P.10
Calenbergh, S.V.11
-
29
-
-
0346100650
-
Anti-mycobacterial agents: 1-Thio analogues of purine
-
Pathak A K, Pathak V, Seitz L E, Reynolds R C & Suling W J, Anti-mycobacterial agents: 1-Thio analogues of purine, J Med Chem, 47 (2004) 273-276.
-
(2004)
J Med Chem
, vol.47
, pp. 273-276
-
-
Pathak, A.K.1
Pathak, V.2
Seitz, L.E.3
Reynolds, R.C.4
Suling, W.J.5
-
30
-
-
0002609577
-
Tuberculosis: A search for novel therapy starting with natural products
-
Baker W R, Mitscher L A, Arain M A, Shaver R & Stover C K, Tuberculosis: A search for novel therapy starting with natural products, Annu Rep Med Chem, 31 (1996) 161-170.
-
(1996)
Annu Rep Med Chem
, vol.31
, pp. 161-170
-
-
Baker, W.R.1
Mitscher, L.A.2
Arain, M.A.3
Shaver, R.4
Stover, C.K.5
-
31
-
-
33947217608
-
-
US Pat 6, 087, 358 Chem Abstrt, 133 (2000) 89525
-
Baker W R, Shaopei C & Keeler E L, US Pat 6, 087, 358 (2000); Chem Abstrt, 133 (2000) 89525.
-
(2000)
-
-
Baker, W.R.1
Shaopei, C.2
Keeler, E.L.3
-
32
-
-
0034702247
-
A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis
-
Stover C K, Warrener P, VanDevanter D R, Sherman D R, Arain T M, Langhorne M H, Anderson S W, Towell J A, Yuan Y, McMurray D N, Kreiswirth B N, Barry C E & Baker W R, A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis, Nature, 405 (2000) 962-966.
-
(2000)
Nature
, vol.405
, pp. 962-966
-
-
Stover, C.K.1
Warrener, P.2
VanDevanter, D.R.3
Sherman, D.R.4
Arain, T.M.5
Langhorne, M.H.6
Anderson, S.W.7
Towell, J.A.8
Yuan, Y.9
McMurray, D.N.10
Kreiswirth, B.N.11
Barry, C.E.12
Baker, W.R.13
-
33
-
-
0027411717
-
In vitro and in vivo activities of the nitroimidazole CGI 17341 against Mycobacterium tuberculosis
-
Ashtekar D R, Rabi C P, Nagrajan K, Vishvanathan N, Bhatt A D & Rittel W, In vitro and in vivo activities of the nitroimidazole CGI 17341 against Mycobacterium tuberculosis, Antimicrob Ag Chemother, 37 (1993) 183-186.
-
(1993)
Antimicrob Ag Chemother
, vol.37
, pp. 183-186
-
-
Ashtekar, D.R.1
Rabi, C.P.2
Nagrajan, K.3
Vishvanathan, N.4
Bhatt, A.D.5
Rittel, W.6
-
34
-
-
0035038011
-
Drug targeting Mycobacterium tuberculosis cell wall synthesis: Genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to
-
Ma Y, Stern R J, Scherman M S, Vissa V D, Yan W, Jones V C, Zhang F, Franzblau S G, Lewis W H & McNeil M R, Drug targeting Mycobacterium tuberculosis cell wall synthesis: genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose, Antimicrob Ag Chemother, 5 (2001) 1407-1416.
-
(2001)
DTDP-rhamnose Antimicrob Ag Chemother
, vol.5
, pp. 1407-1416
-
-
Ma, Y.1
Stern, R.J.2
Scherman, M.S.3
Vissa, V.D.4
Yan, W.5
Jones, V.C.6
Zhang, F.7
Franzblau, S.G.8
Lewis, W.H.9
McNeil, M.R.10
-
35
-
-
0034678644
-
4-Thiazolidinones: Novel inhibitors of the bacterial enzyme MurB
-
Andres C J, Bronson J J, D'Andrea S V, Deshpande M S, Falk P J, Grant-Young K A, Harte W E, Ho H T, Misco P F, Robertson J G, Stock D, Sun Y & Walsh A W, 4-Thiazolidinones: Novel inhibitors of the bacterial enzyme MurB, Bioorg Med Chem Lett, 10 (2000) 715-717.
-
(2000)
Bioorg Med Chem Lett
, vol.10
, pp. 715-717
-
-
Andres, C.J.1
Bronson, J.J.2
D'Andrea, S.V.3
Deshpande, M.S.4
Falk, P.J.5
Grant-Young, K.A.6
Harte, W.E.7
Ho, H.T.8
Misco, P.F.9
Robertson, J.G.10
Stock, D.11
Sun, Y.12
Walsh, A.W.13
-
36
-
-
0034710712
-
A new class of anti-tuberculosis agents
-
Jones P B, Parrish N M, Houston T A, Stapon A, Bansal N P, Dick J D & Townsend C A, A new class of anti-tuberculosis agents, J Med Chem, 43 (2000) 3304-3314.
-
(2000)
J Med Chem
, vol.43
, pp. 3304-3314
-
-
Jones, P.B.1
Parrish, N.M.2
Houston, T.A.3
Stapon, A.4
Bansal, N.P.5
Dick, J.D.6
Townsend, C.A.7
-
37
-
-
0036224240
-
The M. tuberculosis antigen 85 complex and mycolyltransferase activity
-
Kremer L, Maughan W N, Wilson R A, Dover L G & Besra G S, The M. tuberculosis antigen 85 complex and mycolyltransferase activity, Lett Appl Microbiol, 34 (2002) 233-237.
-
(2002)
Lett Appl Microbiol
, vol.34
, pp. 233-237
-
-
Kremer, L.1
Maughan, W.N.2
Wilson, R.A.3
Dover, L.G.4
Besra, G.S.5
-
38
-
-
0036157457
-
Synthesis and biological evaluation of trehalose analogs as potential inhibitors of mycobacterial cell wall biosynthesis
-
Rose J D, Maddry J A, Comber R N, Suling W J, Wilson L N & Reynolds R C, Synthesis and biological evaluation of trehalose analogs as potential inhibitors of mycobacterial cell wall biosynthesis, Carbohydr Res, 337 (2002) 105-120.
-
(2002)
Carbohydr Res
, vol.337
, pp. 105-120
-
-
Rose, J.D.1
Maddry, J.A.2
Comber, R.N.3
Suling, W.J.4
Wilson, L.N.5
Reynolds, R.C.6
-
39
-
-
0028064838
-
Recognition of the lipid intermediate for arabinogalactan/arabinomannan biosynthesis and its relation to the mode of action of ethambutol on mycobacteria
-
Wolucka B A, McNeil M R, deHoffman E, Chojnaki T & Brennan P J, Recognition of the lipid intermediate for arabinogalactan/arabinomannan biosynthesis and its relation to the mode of action of ethambutol on mycobacteria, J Biol Chem, 269 (1994) 23328-23335.
-
(1994)
J Biol Chem
, vol.269
, pp. 23328-23335
-
-
Wolucka, B.A.1
McNeil, M.R.2
deHoffman, E.3
Chojnaki, T.4
Brennan, P.J.5
-
40
-
-
0029977936
-
Polyprenylphosphate-pentoses in mycobacteria are synthesized from 5-phosphoribose pyrophosphate
-
Scherman M S, Kalbe-Bournonville L, Bush D, Xin Y, Deng L & McNeil M, Polyprenylphosphate-pentoses in mycobacteria are synthesized from 5-phosphoribose pyrophosphate, J Biol Chem, 271 (1996) 29652-29658.
-
(1996)
J Biol Chem
, vol.271
, pp. 29652-29658
-
-
Scherman, M.S.1
Kalbe-Bournonville, L.2
Bush, D.3
Xin, Y.4
Deng, L.5
McNeil, M.6
-
41
-
-
0037073950
-
Synthesis and antituberculosis activity of C-phosphonate analogues of decaprenolphosphoarabinose, a key intermediate in the biosynthesis of mycobactedal arabinogalactan and lipoarabinomannan
-
Centrone C A & Lowary T L, Synthesis and antituberculosis activity of C-phosphonate analogues of decaprenolphosphoarabinose, a key intermediate in the biosynthesis of mycobactedal arabinogalactan and lipoarabinomannan. J Org Chem, 67 (2002) 8862-8870.
-
(2002)
J Org Chem
, vol.67
, pp. 8862-8870
-
-
Centrone, C.A.1
Lowary, T.L.2
-
42
-
-
0028156861
-
InhA, a gene encoding a target for isoniazid and ethionamide in M. tuberculosis
-
Banerjee A, Dubnau E, Quemard A, Balasubramanian V, Um K S, Wilson T, Collins D, de Lisle G & Jacobs W R Jr, InhA, a gene encoding a target for isoniazid and ethionamide in M. tuberculosis., Science, 263 (1994) 227-230.
-
(1994)
Science
, vol.263
, pp. 227-230
-
-
Banerjee, A.1
Dubnau, E.2
Quemard, A.3
Balasubramanian, V.4
Um, K.S.5
Wilson, T.6
Collins, D.7
de Lisle, G.8
Jacobs Jr., W.R.9
-
43
-
-
0038757566
-
Targeting tuberculosis and malaria through inhibition of enoyl reductase
-
Kuo M R, Morbidoni H R, Alland D, Sneddon S F, Gourlie B B, Staveski M M, Leonard M, Gregory J S, Janjigian A D, Lee C, Musser J M, Kreiswirth B, Iwamoto H, Perozzo R, Jacobs W R, Sacchettini J C & Fidock D A., Targeting tuberculosis and malaria through inhibition of enoyl reductase, J Biol Chem, 278 (2003) 20851-20859.
-
(2003)
J Biol Chem
, vol.278
, pp. 20851-20859
-
-
Kuo, M.R.1
Morbidoni, H.R.2
Alland, D.3
Sneddon, S.F.4
Gourlie, B.B.5
Staveski, M.M.6
Leonard, M.7
Gregory, J.S.8
Janjigian, A.D.9
Lee, C.10
Musser, J.M.11
Kreiswirth, B.12
Iwamoto, H.13
Perozzo, R.14
Jacobs, W.R.15
Sacchettini, J.C.16
Fidock, D.A.17
-
44
-
-
0005690525
-
-
in by C Curius, S Ghisla & N Blau (Walter de Gruyter, Berlin, Germany)
-
Temple C G, in Chemistry and Biology of Pteridines, by C Curius, S Ghisla & N Blau (Walter de Gruyter, Berlin, Germany) 1990, 1009-1014.
-
Chemistry and Biology of Pteridines
, vol.1990
, pp. 1009-1014
-
-
Temple, C.G.1
-
45
-
-
0020612067
-
1,2-dihydropyrido[3,4-b]pyrazines: Structure-activity relationships
-
Temple C G, Wheeler G P, Elliott R D, Rose J D & Comber R N, Montgomery J A, 1,2-dihydropyrido[3,4-b]pyrazines: Structure-activity relationships, J Med Chem, 26 (1983) 91-95.
-
(1983)
J Med Chem
, vol.26
, pp. 91-95
-
-
Temple, C.G.1
Wheeler, G.P.2
Elliott, R.D.3
Rose, J.D.4
Comber, R.N.5
Montgomery, J.A.6
-
46
-
-
0035996108
-
2-Alkoxycarbonylaminopyridines: Inhibitors of Mycobacterium tuberculosis FtsZ
-
White E L, Suling W J, Ross L J, Seitz L E & Reynolds R C, 2-Alkoxycarbonylaminopyridines: Inhibitors of Mycobacterium tuberculosis FtsZ., J Antimicrob Chemother, 50 (2002) 111-114.
-
(2002)
J Antimicrob Chemother
, vol.50
, pp. 111-114
-
-
White, E.L.1
Suling, W.J.2
Ross, L.J.3
Seitz, L.E.4
Reynolds, R.C.5
-
47
-
-
0033802522
-
Antimycobacterial activities of 2,4-diamino-5-deazapteridine derivatives and effects on mycobacterial dihydrofolate reductase
-
Suling W J, Seitz L E, Pathak V, Westbrook L, Barrow E W, Zywno-Van-Ginkel S, Reynolds R C, Piper J R & Barrow W W, Antimycobacterial activities of 2,4-diamino-5-deazapteridine derivatives and effects on mycobacterial dihydrofolate reductase, Antimicrob Ag Chemother, 44 (2000) 2784-2793.
-
(2000)
Antimicrob Ag Chemother
, vol.44
, pp. 2784-2793
-
-
Suling, W.J.1
Seitz, L.E.2
Pathak, V.3
Westbrook, L.4
Barrow, E.W.5
Zywno-Van-Ginkel, S.6
Reynolds, R.C.7
Piper, J.R.8
Barrow, W.W.9
-
48
-
-
0036754614
-
Synthesis of glycosylated beta-amino acids as new class of antitubercular agents
-
Tripathi R. P, Tripathi R, Tiwari V K, Bala L, Sinha S, Srivastava A, Srivastava R & Srivastava B S, Synthesis of glycosylated beta-amino acids as new class of antitubercular agents, Eur J Med Chem, 37 (2002) 773-781.
-
(2002)
Eur J Med Chem
, vol.37
, pp. 773-781
-
-
Tripathi, R.P.1
Tripathi, R.2
Tiwari, V.K.3
Bala, L.4
Sinha, S.5
Srivastava, A.6
Srivastava, R.7
Srivastava, B.S.8
-
49
-
-
0022479574
-
Single amino acid substitutions in the enzyme acetolactate synthase confer resistance to the herbicide sulfometuron methyl
-
Yadav N, McDevitt R E, Benard S & Falco S C, Single amino acid substitutions in the enzyme acetolactate synthase confer resistance to the herbicide sulfometuron methyl, Proc Natl Acad Sci, 83 (1986) 4418-4422.
-
(1986)
Proc Natl Acad Sci
, vol.83
, pp. 4418-4422
-
-
Yadav, N.1
McDevitt, R.E.2
Benard, S.3
Falco, S.C.4
-
50
-
-
0034678644
-
4-Thiazolidinones: Novel inhibitors of the bacterial enzyme MurB
-
Andres C J, Bronson J J, D'Andrea S V, Deshpande M S, Falk P J, Grant-Young K A, Harte W E, Ho H T, Misco P F, Robertson J G, Stock D, Sun Y & Walsh A W, 4-Thiazolidinones: novel inhibitors of the bacterial enzyme MurB, Bioorg Med Chem Lett, 10 (2000) 715-717.
-
(2000)
Bioorg Med Chem Lett
, vol.10
, pp. 715-717
-
-
Andres, C.J.1
Bronson, J.J.2
D'Andrea, S.V.3
Deshpande, M.S.4
Falk, P.J.5
Grant-Young, K.A.6
Harte, W.E.7
Ho, H.T.8
Misco, P.F.9
Robertson, J.G.10
Stock, D.11
Sun, Y.12
Walsh, A.W.13
-
51
-
-
2942550559
-
Novel pyridazino[4,3-b]indoles with dual inhibitory activity against M. tuberculosis and monoamine oxidase
-
Velezheva V S, Brennan P J, Marshakov V Y, Gusev D V, Lisichkina I N, Pergudov A S, Tchernousova L N, Smirnova T G, Andreevskaya S N & Medvedev A E, Novel pyridazino[4,3-b]indoles with dual inhibitory activity against M. tuberculosis and monoamine oxidase, J Med Chem, 47 (2004) 3455-3461.
-
(2004)
J Med Chem
, vol.47
, pp. 3455-3461
-
-
Velezheva, V.S.1
Brennan, P.J.2
Marshakov, V.Y.3
Gusev, D.V.4
Lisichkina, I.N.5
Pergudov, A.S.6
Tchernousova, L.N.7
Smirnova, T.G.8
Andreevskaya, S.N.9
Medvedev, A.E.10
-
52
-
-
19944429772
-
A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis
-
Andries K, A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis, Science, 307 (2005) 223-227.
-
(2005)
Science
, vol.307
, pp. 223-227
-
-
Andries, K.1
-
53
-
-
0037075792
-
Synthesis and antimycobacterial activity of 6-arylpurines: The requirements for the N-9 substituent in active anti-mycobacterial purines
-
Gundersen L, Nissen-Meyer J & Spilsberg B, Synthesis and antimycobacterial activity of 6-arylpurines: The requirements for the N-9 substituent in active anti-mycobacterial purines, J Med Chem, 45 (2002) 1383-1386.
-
(2002)
J Med Chem
, vol.45
, pp. 1383-1386
-
-
Gundersen, L.1
Nissen-Meyer, J.2
Spilsberg, B.3
-
54
-
-
0346100650
-
Anti-mycobacterial agents: 1-Thio analogues of purine
-
Pathak A K, Pathak V, Seitz L E, Suling W J & Reynolds R C, Anti-mycobacterial agents: 1-Thio analogues of purine, J Med Chem, 47 (2004) 273-276.
-
(2004)
J Med Chem
, vol.47
, pp. 273-276
-
-
Pathak, A.K.1
Pathak, V.2
Seitz, L.E.3
Suling, W.J.4
Reynolds, R.C.5
-
55
-
-
19544390716
-
New small-molecule synthetic antimycobacterials
-
Ballell L, Field R A, Duncan K & Young R J, New small-molecule synthetic antimycobacterials, Antimicrob Ag Chemother, 49 (2005) 2153-2163.
-
(2005)
Antimicrob Ag Chemother
, vol.49
, pp. 2153-2163
-
-
Ballell, L.1
Field, R.A.2
Duncan, K.3
Young, R.J.4
-
56
-
-
0031753303
-
Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains
-
Deidda D, Lampis G, Fioravanti R, Biava M, Portea G, Zanetti S & Pompei R, Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains, Antimicrob Ag Chemother, 42 (1998) 3035-3037.
-
(1998)
Antimicrob Ag Chemother
, vol.42
, pp. 3035-3037
-
-
Deidda, D.1
Lampis, G.2
Fioravanti, R.3
Biava, M.4
Portea, G.5
Zanetti, S.6
Pompei, R.7
-
57
-
-
0036029005
-
BM 212 and its derivatives as a new class of anti-mycobacterial active agents
-
Biava M, BM 212 and its derivatives as a new class of anti-mycobacterial active agents, Curr Med Chem, 9 (1995) 1859-1869.
-
(1995)
Curr Med Chem
, vol.9
, pp. 1859-1869
-
-
Biava, M.1
-
58
-
-
0035833112
-
Anti-mycobacterial activity of 9-sulfonylated/ sulfenylated-6-mercaptopurine derivatives
-
Scozzafava A, Mastrolenzo A & Supuran C T, Anti-mycobacterial activity of 9-sulfonylated/sulfenylated-6-mercaptopurine derivatives, Bioorg Med Chem Lett, 11 (2001) 1675-1678.
-
(2001)
Bioorg Med Chem Lett
, vol.11
, pp. 1675-1678
-
-
Scozzafava, A.1
Mastrolenzo, A.2
Supuran, C.T.3
-
59
-
-
0036009868
-
Higher acyclic nitrogen containing deoxy sugar derivatives: A new lead in the generation of antimycobacterial chemotherapeutics
-
Pathak R, Shaw A K, Bhaduri A P, Chandrasekhar K V G, Sinha S, Srivastava A, Srivastava K K, Chaturvedi V, Srivastava R, Srivastava B S & Arora S, Higher acyclic nitrogen containing deoxy sugar derivatives: a new lead in the generation of antimycobacterial chemotherapeutics. Bioorg Med Chem, 10 (2002) 1695-1702.
-
(2002)
Bioorg Med Chem
, vol.10
, pp. 1695-1702
-
-
Pathak, R.1
Shaw, A.K.2
Bhaduri, A.P.3
Chandrasekhar, K.V.G.4
Sinha, S.5
Srivastava, A.6
Srivastava, K.K.7
Chaturvedi, V.8
Srivastava, R.9
Srivastava, B.S.10
Arora, S.11
-
60
-
-
0036339777
-
Baylis-Hillman reaction: Convenient ascending syntheses and biological evaluation of acyclic deoxy monosaccharides as potential anti-mycobacterial agents
-
Pathak R, Pant C S, Shaw A K, Bhaduri A P, Gaikwad A N, Sinha S, Srivastava A, Srivastava K K, Chaturvedi V, Srivastava R & Srivastava B S, Baylis-Hillman reaction: Convenient ascending syntheses and biological evaluation of acyclic deoxy monosaccharides as potential anti-mycobacterial agents, Bioorg Med Chem, 10 (2002) 3187-3196.
-
(2002)
Bioorg Med Chem
, vol.10
, pp. 3187-3196
-
-
Pathak, R.1
Pant, C.S.2
Shaw, A.K.3
Bhaduri, A.P.4
Gaikwad, A.N.5
Sinha, S.6
Srivastava, A.7
Srivastava, K.K.8
Chaturvedi, V.9
Srivastava, R.10
Srivastava, B.S.11
-
61
-
-
0033594440
-
Synthesis and antimalarial activity of 11 dispiro-1,2,4,5-tetraoxane analogues of WR 148999. 7,8,15,16-tetraoxadispiro[5.2.5.2]hexadecanes substituted at the 1 and 10 positions with unsaturated and polar functional groups
-
Dong Y, Matile H, Chollet J, Kaminsky R, Wood K & Vennerstrom J L, Synthesis and antimalarial activity of 11 dispiro-1,2,4,5-tetraoxane analogues of WR 148999. 7,8,15,16-tetraoxadispiro[5.2.5.2]hexadecanes substituted at the 1 and 10 positions with unsaturated and polar functional groups, J Med Chem, 42 (1999) 1477-1480.
-
(1999)
J Med Chem
, vol.42
, pp. 1477-1480
-
-
Dong, Y.1
Matile, H.2
Chollet, J.3
Kaminsky, R.4
Wood, K.5
Vennerstrom, J.L.6
-
62
-
-
0018101097
-
Chemical constituents of Gentianaceae. XXIV. Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs
-
Ghosal S, Biswas K & Chauduri R K, Chemical constituents of Gentianaceae. XXIV. Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs, J Pharm Sci, 67 (1978) 721-722.
-
(1978)
J Pharm Sci
, vol.67
, pp. 721-722
-
-
Ghosal, S.1
Biswas, K.2
Chauduri, R.K.3
-
63
-
-
0036241998
-
Synthesis and anti-tubercular evaluation of 4-quinolylhydrazones
-
Savini L, Chiasserini L, Gaeta A & Pellerano C, Synthesis and anti-tubercular evaluation of 4-quinolylhydrazones, Bioorg Med Chem, 10 (2002) 2193-2198.
-
(2002)
Bioorg Med Chem
, vol.10
, pp. 2193-2198
-
-
Savini, L.1
Chiasserini, L.2
Gaeta, A.3
Pellerano, C.4
-
64
-
-
0035445139
-
Influence of the replacement of the oxo function with the thioxo group on the antimycobacterial activity of 3-aryl-6,8-dichloro-2H-1,3-benzoxazine-2,4(3H)-diones and 3-arylquinazoline-2,4(1H,3H)-diones
-
Waisser K, Gregor J, Dostál H, Kubicová L, Klimeǒvá V & Kaustová J, Influence of the replacement of the oxo function with the thioxo group on the antimycobacterial activity of 3-aryl-6,8-dichloro-2H-1,3-benzoxazine-2,4(3H)-diones and 3-arylquinazoline-2,4(1H,3H)-diones, Farmaco. 56 (2001) 803-807.
-
(2001)
Farmaco
, vol.56
, pp. 803-807
-
-
Waisser, K.1
Gregor, J.2
Dostál, H.3
Kubicová, L.4
Klimeǒvá, V.5
Kaustová, J.6
-
65
-
-
0037332267
-
Antimycobacterial 3-aryl-2H-1,3-benzoxazine-2,4(3H)-diones
-
Waisser K, Bures O, Holy P, Kunes J, Oswald R, Jiraskova L, Pour M, Klimesova V, Palat K, Kaustova J, Danse H M & Mollmann U, Antimycobacterial 3-aryl-2H-1,3-benzoxazine-2,4(3H)-diones, Pharmazie, 58 (2003) 83-94.
-
(2003)
Pharmazie
, vol.58
, pp. 83-94
-
-
Waisser, K.1
Bures, O.2
Holy, P.3
Kunes, J.4
Oswald, R.5
Jiraskova, L.6
Pour, M.7
Klimesova, V.8
Palat, K.9
Kaustova, J.10
Danse, H.M.11
Mollmann, U.12
-
66
-
-
0034830902
-
Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1,4-di-N-oxide
-
Ganley B, Chowdhury G, Bhansali J, Daniels J S & Gates K S, Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1,4-di-N-oxide, Bioorg Med Chem, 9 (2001) 2395-2401.
-
(2001)
Bioorg Med Chem
, vol.9
, pp. 2395-2401
-
-
Ganley, B.1
Chowdhury, G.2
Bhansali, J.3
Daniels, J.S.4
Gates, K.S.5
-
67
-
-
1342324049
-
Synthesis, anti-mycobacterial, anti-trichomonas and anti-candida in vitro activities of 2-substituted-6,7-difluoro-3-methylquinoxaline 1,4-dioxides
-
Carta A, Loriga M, Paglietti G, Mattana A, Fiori P L, Mollicotti P, Sechi L & Zannetti S, Synthesis, anti-mycobacterial, anti-trichomonas and anti-candida in vitro activities of 2-substituted-6,7-difluoro-3-methylquinoxaline 1,4-dioxides, Eur J Med Chem, 39 (2004) 195-203.
-
(2004)
Eur J Med Chem
, vol.39
, pp. 195-203
-
-
Carta, A.1
Loriga, M.2
Paglietti, G.3
Mattana, A.4
Fiori, P.L.5
Mollicotti, P.6
Sechi, L.7
Zannetti, S.8
-
68
-
-
0035093384
-
Anti-mycobacterial activity of new quinoxaline-2-carbonitrile and quinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives
-
Ortega M A, Montoya M E, Jaso A, Zarranz B, Tirapu I, Aldana I & Monge A, Anti-mycobacterial activity of new quinoxaline-2-carbonitrile and quinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives, Pharmazie, 56 (2001) 205-207.
-
(2001)
Pharmazie
, vol.56
, pp. 205-207
-
-
Ortega, M.A.1
Montoya, M.E.2
Jaso, A.3
Zarranz, B.4
Tirapu, I.5
Aldana, I.6
Monge, A.7
-
69
-
-
0037447952
-
Synthesis and antimycobacterial activity of new quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives
-
Zarranz B, Jaso A, Aldana I & Monge A, Synthesis and antimycobacterial activity of new quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives, Bioorg Med Chem, 11 (2003) 2149-2156.
-
(2003)
Bioorg Med Chem
, vol.11
, pp. 2149-2156
-
-
Zarranz, B.1
Jaso, A.2
Aldana, I.3
Monge, A.4
-
70
-
-
0001945179
-
Design of compounds active against Mycobacterium tuberculosis
-
Waisser K, Klimesova V & Odlerová Z, Design of compounds active against Mycobacterium tuberculosis, Folia Pharm Univ Carol, 18 (1995) 31-37.
-
(1995)
Folia Pharm Univ Carol
, vol.18
, pp. 31-37
-
-
Waisser, K.1
Klimesova, V.2
Odlerová, Z.3
-
71
-
-
0030762464
-
Synthesis and antimycobacterial activity of some new 3-heterocyclic substituted chromones
-
Gasparova R, Lacova M, El-Shaaer H M & Odlerová Z, Synthesis and antimycobacterial activity of some new 3-heterocyclic substituted chromones, Farmaco, 52 (1997) 251-253.
-
(1997)
Farmaco
, vol.52
, pp. 251-253
-
-
Gasparova, R.1
Lacova, M.2
El-Shaaer, H.M.3
Odlerová, Z.4
-
72
-
-
0141923187
-
Synthesis and biological evaluation of benzo[d]isothiazole, benzothiazole and thiazole Schiff bases
-
Vicini P, Geronikaki A, Incerti M, Busonera B, Poni G, Cabras C A & La Co!la P, Synthesis and biological evaluation of benzo[d]isothiazole, benzothiazole and thiazole Schiff bases, Bioorg Med Chem, 11 (2003) 4785-4789.
-
(2003)
Bioorg Med Chem
, vol.11
, pp. 4785-4789
-
-
Vicini, P.1
Geronikaki, A.2
Incerti, M.3
Busonera, B.4
Poni, G.5
Cabras, C.A.6
La Colla, P.7
-
73
-
-
0036241998
-
Synthesis and anti-tubercular evaluation of 4-quinolylhydrazones
-
Savini L, Chiasserini L, Gaeta A & Pellerano C, Synthesis and anti-tubercular evaluation of 4-quinolylhydrazones, Bioorg Med Chem, 10 (2002) 2193-2198.
-
(2002)
Bioorg Med Chem
, vol.10
, pp. 2193-2198
-
-
Savini, L.1
Chiasserini, L.2
Gaeta, A.3
Pellerano, C.4
-
74
-
-
0036121495
-
Synthesis of 1,3-thiazine derivatives and their evaluation as potential antimycobacterial agents
-
Koketsu M, Tanaka K, Takenaka Y, Kwong C D & Ishihara H, Synthesis of 1,3-thiazine derivatives and their evaluation as potential antimycobacterial agents, Eur J Pharm Sci, 15 (2002) 307-310.
-
(2002)
Eur J Pharm Sci
, vol.15
, pp. 307-310
-
-
Koketsu, M.1
Tanaka, K.2
Takenaka, Y.3
Kwong, C.D.4
Ishihara, H.5
-
76
-
-
0035492471
-
Synthesis, antimycobacterial activities and cytotoxicity on V79 of 3-[4′-Y-(1,1′-biphenyl)-4-yl]-N,N-dimethyl-3-(4-X-phenyl)-2- propen-1-amine derivatives
-
De Souza A O, Santos R R Jr, Ferreira-Julio J F, Rodríguez J A, Melo P S, Haun M, Sato D N & Durán N, Synthesis, antimycobacterial activities and cytotoxicity on V79 of 3-[4′-Y-(1,1′-biphenyl)-4-yl]-N,N-dimethyl-3-(4-X-phenyl)-2- propen-1-amine derivatives. Eur J Med Chem, 36 (2001) 843-850.
-
(2001)
Eur J Med Chem
, vol.36
, pp. 843-850
-
-
De Souza, A.O.1
Santos Jr., R.R.2
Ferreira-Julio, J.F.3
Rodríguez, J.A.4
Melo, P.S.5
Haun, M.6
Sato, D.N.7
Durán, N.8
-
77
-
-
0034633853
-
Combination of molecular modeling and quantitative structure-activity relationship analysis in the study of antimycobacterial activity of pyridine derivatives
-
Klimesova V, Palat K, Waisser K & Klimes J, Combination of molecular modeling and quantitative structure-activity relationship analysis in the study of antimycobacterial activity of pyridine derivatives, Int J Pharm, 207 (2000) 1-6.
-
(2000)
Int J Pharm
, vol.207
, pp. 1-6
-
-
Klimesova, V.1
Palat, K.2
Waisser, K.3
Klimes, J.4
-
78
-
-
0036170331
-
Chloropyrimidines as a new class of antimicrobial agents
-
Agarwal N, Srivastava P, Raghuwanshi S K, Upadhyay D N, Sinha S, Shukla P K & Ram V J, Chloropyrimidines as a new class of antimicrobial agents, Bioorg Med Chem, 10 (2002) 869-874.
-
(2002)
Bioorg Med Chem
, vol.10
, pp. 869-874
-
-
Agarwal, N.1
Srivastava, P.2
Raghuwanshi, S.K.3
Upadhyay, D.N.4
Sinha, S.5
Shukla, P.K.6
Ram, V.J.7
-
79
-
-
0006987982
-
New toluidine derivatives with antimycobacterial and antifungal activities
-
Biava M, Fioravanti R, Porretta G C, Sleiter G, Ettorre A, Deidda D, Lampis G & Pompei R, New toluidine derivatives with antimycobacterial and antifungal activities, Med Chem Res, (1997) 228-250.
-
(1997)
Med Chem Res
, pp. 228-250
-
-
Biava, M.1
Fioravanti, R.2
Porretta, G.C.3
Sleiter, G.4
Ettorre, A.5
Deidda, D.6
Lampis, G.7
Pompei, R.8
-
80
-
-
0032429957
-
Toluidine derivatives with antimycobacterial and antifungal activities
-
Biava M, Fioravanti R, Porretta G C, Sleiter G, Ettorre A, Deidda D, Lampis G & Pompei R, Toluidine derivatives with antimycobacterial and antifungal activities, Med Chem Res, (1998) 523-533.
-
(1998)
Med Chem Res
, pp. 523-533
-
-
Biava, M.1
Fioravanti, R.2
Porretta, G.C.3
Sleiter, G.4
Ettorre, A.5
Deidda, D.6
Lampis, G.7
Pompei, R.8
-
81
-
-
0035048959
-
Antimycobacterial activity of 1-deaza-7,8-dihydropteridine derivatives against Mycobacterium tuberculosis and Mycobacterium avium complex in vitro
-
Suling W J & Maddry J A, Antimycobacterial activity of 1-deaza-7,8-dihydropteridine derivatives against Mycobacterium tuberculosis and Mycobacterium avium complex in vitro, J Antimicrob Chemother, 47 (2001) 451-454.
-
(2001)
J Antimicrob Chemother
, vol.47
, pp. 451-454
-
-
Suling, W.J.1
Maddry, J.A.2
-
82
-
-
0034058145
-
Oxazolidinones, A review
-
Diekema D J & Jones R N, Oxazolidinones, A review, Drugs, 59 (2000) 7-16.
-
(2000)
Drugs
, vol.59
, pp. 7-16
-
-
Diekema, D.J.1
Jones, R.N.2
-
83
-
-
0029942573
-
In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents
-
Zurenko G E, Yagi B H, Schaadt R D, Allison J W, Kilburn J O, Glickman S E, Hutchinson D K, Barbachyn M R & Brickner S J, In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents, Antimicrob Ag Chemother, 40 (1996) 839-845.
-
(1996)
Antimicrob Ag Chemother
, vol.40
, pp. 839-845
-
-
Zurenko, G.E.1
Yagi, B.H.2
Schaadt, R.D.3
Allison, J.W.4
Kilburn, J.O.5
Glickman, S.E.6
Hutchinson, D.K.7
Barbachyn, M.R.8
Brickner, S.J.9
-
84
-
-
13344284628
-
Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity
-
Barbachyn M R, Hutchinson, Brickner S J, Cynamon M H, Kilburn J O, Klemens S P, Glickman S E, Grega K C, Hendges S K, Toops D S, Ford C W & Zurenko G E, Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity, J Med Chem, 39 (1996) 680-685.
-
(1996)
J Med Chem
, vol.39
, pp. 680-685
-
-
Barbachyn, M.R.1
Hutchinson Brickner, S.J.2
Cynamon, M.H.3
Kilburn, J.O.4
Klemens, S.P.5
Glickman, S.E.6
Grega, K.C.7
Hendges, S.K.8
Toops, D.S.9
Ford, C.W.10
Zurenko, G.E.11
-
85
-
-
0013797020
-
Studies on pyrrolnitrin, a new antibiotic. I. Isolation and properties of pyrrolnitri
-
Arima K, Imanaka H, Kousaka M, Fukuda A & Tamura G, Studies on pyrrolnitrin, a new antibiotic. I. Isolation and properties of pyrrolnitri, J Antibiot Ser A, 18 (1968) 201-204.
-
(1968)
J Antibiot Ser A
, vol.18
, pp. 201-204
-
-
Arima, K.1
Imanaka, H.2
Kousaka, M.3
Fukuda, A.4
Tamura, G.5
-
86
-
-
1842630349
-
Synthesis and preliminary evaluation of some pyrazine containing thiazolines and thiazolidinones as antimicrobial agents
-
Bonde C G & Gaikwad N J, Synthesis and preliminary evaluation of some pyrazine containing thiazolines and thiazolidinones as antimicrobial agents, Bioorg Med Chem, 12 (2004) 2151-2161.
-
(2004)
Bioorg Med Chem
, vol.12
, pp. 2151-2161
-
-
Bonde, C.G.1
Gaikwad, N.J.2
-
87
-
-
0033913636
-
New groups of antimycobacterial agents: 6-chloro-3-phenyl-4-thioxo-2H-1,3-benzoxazine-2(3H)-ones and 6-chloro-3-phenyl-2H-1,3-benzoxazine-2,4(3H)-dithiones
-
Waisser K, Gregor J, Kubicova L, Klimesova V, Kunes J, Machacek M & Kaustova J, New groups of antimycobacterial agents: 6-chloro-3-phenyl-4-thioxo-2H-1,3-benzoxazine-2(3H)-ones and 6-chloro-3-phenyl-2H-1,3-benzoxazine-2,4(3H)-dithiones, Eur J Med Chem, 35 (2000) 733-741.
-
(2000)
Eur J Med Chem
, vol.35
, pp. 733-741
-
-
Waisser, K.1
Gregor, J.2
Kubicova, L.3
Klimesova, V.4
Kunes, J.5
Machacek, M.6
Kaustova, J.7
-
88
-
-
0033549680
-
Novel antimycobacterial benzoxazole alkaloids from the West Indian Sea whip Pseudopterogorgia elisabethae
-
Rodriguez A D, Ramirez C, Rodriguez II & Gonzalez E, Novel antimycobacterial benzoxazole alkaloids from the West Indian Sea whip Pseudopterogorgia elisabethae, Org Letts, 1 (1999) 527-530.
-
(1999)
Org Letts
, vol.1
, pp. 527-530
-
-
Rodriguez, A.D.1
Ramirez, C.2
Rodriguez, I.I.3
Gonzalez, E.4
-
89
-
-
0031734041
-
Tuberculosis: A search for novel therapy starting with natural products
-
Mitscher L A & Baker W, Tuberculosis: A search for novel therapy starting with natural products, Med Res Rev, 18 (1997) 363-374.
-
(1997)
Med Res Rev
, vol.18
, pp. 363-374
-
-
Mitscher, L.A.1
Baker, W.2
-
90
-
-
0033987119
-
In vitro Investigation of the Antimicrobial Activities of Novel Tetramethylpiperidine-Substituted Phenazines against Mycobacterium tuberculosis
-
Van Rensburg C E J, Joone G K, Sirgel F A, Matlola N M & O'Sullivan J F, In vitro Investigation of the Antimicrobial Activities of Novel Tetramethylpiperidine-Substituted Phenazines against Mycobacterium tuberculosis, Chemother, 46 (2000) 43-48.
-
(2000)
Chemother
, vol.46
, pp. 43-48
-
-
Van Rensburg, C.E.J.1
Joone, G.K.2
Sirgel, F.A.3
Matlola, N.M.4
O'Sullivan, J.F.5
-
91
-
-
14444274371
-
Pyranocoumarins from tropical species of the genus Calophyllum: A chemotaxonomic study of extracts in the National Cancer Institute collection
-
McKee T C, Covington C D, Fuller R W, Bokesch H R, Young S, Cardellina II J H, Kadushin M R, Soejarto D D, Stevens P F, Cragg G M & Boyd M R, Pyranocoumarins from tropical species of the genus Calophyllum: A chemotaxonomic study of extracts in the National Cancer Institute collection, J Nat Prod, 61 (1998) 1252-1256.
-
(1998)
J Nat Prod
, vol.61
, pp. 1252-1256
-
-
McKee, T.C.1
Covington, C.D.2
Fuller, R.W.3
Bokesch, H.R.4
Young, S.5
Cardellina II, J.H.6
Kadushin, M.R.7
Soejarto, D.D.8
Stevens, P.F.9
Cragg, G.M.10
Boyd, M.R.11
-
92
-
-
0030439224
-
Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1
-
Currens M J, Gulakowski R J, Mariner J M, Moran R A, Buckheit R W Jr., Gustafson K R, McMahon J B & Boyd M R, Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1, J Pharmacol Exp Therap, 279 (1996) 645-651.
-
(1996)
J Pharmacol Exp Therap
, vol.279
, pp. 645-651
-
-
Currens, M.J.1
Gulakowski, R.J.2
Mariner, J.M.3
Moran, R.A.4
Buckheit Jr., R.W.5
Gustafson, K.R.6
McMahon, J.B.7
Boyd, M.R.8
-
93
-
-
0031806247
-
Inhibition of human immunodeficiency virus type 1 reverse transcriptase activity by cordatolides isolated from Calophyllum cordato-oblongum
-
Dharmaratne H R, Wanigasekera W M, Mata-Greenwood E & Pezzuto J M, Inhibition of human immunodeficiency virus type 1 reverse transcriptase activity by cordatolides isolated from Calophyllum cordato-oblongum, Planta Medica, 64 (1998) 460-461.
-
(1998)
Planta Medica
, vol.64
, pp. 460-461
-
-
Dharmaratne, H.R.1
Wanigasekera, W.M.2
Mata-Greenwood, E.3
Pezzuto, J.M.4
-
96
-
-
0033971447
-
Pharmacokinetics and tissue distribution of rifametane, a new 3-azinomethyl-rifamycin derivative, in several animal species
-
Bruzzese T, Rimaroli C, Bonabello A, Mozzi G, Ajay S & Cooverj N D, Pharmacokinetics and tissue distribution of rifametane, a new 3-azinomethyl-rifamycin derivative, in several animal species, Arzneimittel-Forschung, 50 (2000) 60-71.
-
(2000)
Arzneimittel-Forschung
, vol.50
, pp. 60-71
-
-
Bruzzese, T.1
Rimaroli, C.2
Bonabello, A.3
Mozzi, G.4
Ajay, S.5
Cooverj, N.D.6
-
97
-
-
0023733430
-
The antibacterial activity of a new 3-azinomethylrifamycin
-
Strippoli V, Bruzzese T, Galli R & Siminetti N, The antibacterial activity of a new 3-azinomethylrifamycin. Il Farmaco Ed Sci, 43 (1988) 619-625.
-
(1988)
Il Farmaco Ed Sci
, vol.43
, pp. 619-625
-
-
Strippoli, V.1
Bruzzese, T.2
Galli, R.3
Siminetti, N.4
-
98
-
-
0030961425
-
Treatment of multidrug-resistant pulmonary tuberculosis with interferon-gamma via aerosol
-
Condos R, Rom W M & Schluger N W, Treatment of multidrug-resistant pulmonary tuberculosis with interferon-gamma via aerosol, Lancet, 349 (1997) 1513-1515.
-
(1997)
Lancet
, vol.349
, pp. 1513-1515
-
-
Condos, R.1
Rom, W.M.2
Schluger, N.W.3
-
99
-
-
0029295913
-
Thalidomide treatment reduces tumour necrosis factor production and enhances weight gain in patients with pulmonary tuberculosis
-
Tramontana J M, Utaipat T, Molloy A, Akarasewi P, Burroughs M, Makonkawkeyoon S, Johnson B, Klausner J D, Rom W & Kaplan G, Thalidomide treatment reduces tumour necrosis factor production and enhances weight gain in patients with pulmonary tuberculosis. Molec Med, 1 (1995) 384-387.
-
(1995)
Molec Med
, vol.1
, pp. 384-387
-
-
Tramontana, J.M.1
Utaipat, T.2
Molloy, A.3
Akarasewi, P.4
Burroughs, M.5
Makonkawkeyoon, S.6
Johnson, B.7
Klausner, J.D.8
Rom, W.9
Kaplan, G.10
-
100
-
-
0034679958
-
Lipid lunch for persistent pathogen
-
Bishai W, Lipid lunch for persistent pathogen, Nature, 406 (2000) 683-685.
-
(2000)
Nature
, vol.406
, pp. 683-685
-
-
Bishai, W.1
-
101
-
-
0342794213
-
Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase 101 Nature
-
McKinney J D, Honer zu Bentrup K, Munoz Elias E J, Miczak A, Chen B, Chan W T, Swenson D, Sacchettini J C, Jacobs W R Jr & Russell D G, Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase, Nature, 406 (2000) 735-738.
-
(2000)
, vol.406
, pp. 735-738
-
-
McKinney, J.D.1
Honer zu Bentrup, K.2
Munoz Elias, E.J.3
Miczak, A.4
Chen, B.5
Chan, W.T.6
Swenson, D.7
Sacchettini, J.C.8
Jacobs Jr., W.R.9
Russell, D.G.10
|