New groups of antimycobacterial agents: 6-chloro-3-phenyl-4-thioxo-2H- 1,3-benzoxazine-2(3H)-ones and 6-chloro-3-phenyl-2H-1,3-benzoxazine-2,4(3H)- dithiones

European Journal of Medicinal Chemistry

Volumn 35, Issue 7-8, 2000, Pages 733-741

  Waisser, Karel ^a   Gregor, Jiří ^a   Kubicová, Lenka ^a   Klimešová, Věra ^a   Kuneš, Jiří ^a   MacHáček, Miloš ^a   Kaustová, Jarmila ^b  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^b Regional Institute of Hygiene   (Czech Republic)

Author keywords

1,3 benzoxazine 2,4 diones; 1,3 benzoxazine 2,4 dithiones; 4 thioxo 1,3 benzoxazine 2 ones; Antimycobacterial activity; Cosine coefficient; Quantitative structure activity relationship

Indexed keywords

6 CHLORO 3 PHENYL 2H 1,3 BENZOXAZINE 2,4(3H)DITHIONE; 6 CHLORO 3 PHENYL 4 THIOXO 2H 1,3 BENZOXAZINE 2(3H) ONE; ANTIMYCOBACTERIAL AGENT; ISONIAZID; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL MODIFICATION; DRUG SYNTHESIS; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REACTION ANALYSIS; TUBERCULOSIS;

EID: 0033913636     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(00)00174-4     Document Type: Article

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