Synthesis, antimycobacterial activities and cytotoxicity on V79 of 3-[4′-Y-(1,1′-biphenyl)-4-yl]-N,N-dimethyl-3-(4-X-phenyl)-2- propen-1-amine derivatives

European Journal of Medicinal Chemistry

Volumn 36, Issue 10, 2001, Pages 843-850

  De Souza, Ana O ^a   Santos Júnior, Rubens R ^b   Ferreira Júlio, João F ^a   Rodriguez, Jaime A ^c   Melo, Patrícia S ^a   Haun, Marcela ^a   Sato, Daisy N ^b   Durán, Nelson ^a,d  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b INSTITUTO ADOLFO LUTZ   (Brazil)

^c UNIVERSIDAD DE TALCA   (Chile)

^d UNIVERSIDADE DE MOGI DAS CRUZES   (Brazil)

Author keywords

2 propen 1 amine; Antimycobacterial activity; Cytotoxicity; Synthesis; V79 cells

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AMINE; ANTIMYCOBACTERIAL AGENT; NEUTRAL RED; NUCLEIC ACID;

ACYLATION; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIUM ISOLATION; CELL VIABILITY; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFECT; DRUG SYNTHESIS; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEIC ACID ANALYSIS; REDUCTION; WITTIG REACTION;

ALKENES; ANIMALS; ANTITUBERCULAR AGENTS; BIPHENYL COMPOUNDS; CELL LINE; CRICETINAE; FIBROBLASTS; LUNG; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS;

EID: 0035492471     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(01)01263-6     Document Type: Article

References (20)