The M. tuberculosis antigen 85 complex and mycolyltransferase activity

Letters in Applied Microbiology

Volumn 34, Issue 4, 2002, Pages 233-237

  Kremer, L ^a   Maughan, W N ^a   Wilson, R A ^a   Dover, L G ^a   Besra, G S ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI; MONOCLONAL ANTIBODIES; RECOMBINANT PROTEINS; TUBES (COMPONENTS);

CELL WALLS; CONDITION; HETEROLOGOUS EXPRESSION; IN-VITRO; M. TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; SECRETED PROTEIN;

ANTIGENS;

BACTERIAL ANTIGEN; ENZYME; MONOCLONAL ANTIBODY; MYCOLYLTRANSFERASE; PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

TUBERCULOSIS;

ANALYTIC METHOD; ARTICLE; CELL WALL; CONTROLLED STUDY; DENATURATION; ENZYME ACTIVITY; ESCHERICHIA COLI; GENOME; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN PURIFICATION; TUBERCULOSIS;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NEGIBACTERIA; UNCULTURED ACTINOMYCETE;

EID: 0036224240     PISSN: 02668254     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1472-765x.2002.01091.x     Document Type: Article

References (12)

1. Characterization of fibronectin-binding antigens released by Mycobacterium tuberculosis and Mycobacterium bovis BCG
2. An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (Antigen 85B), a mycolyl transferase
3. Disruption of the genes encoding antigen 85A and antigen 85B of Mycobacterium tuberculosis H37Rv: Effect on growth in culture and in macrophages
4. Role of the major antigen of Myco-bacterium tuberculosis in cell wall biogenesis
5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
6. Isoelectrophoretic characterization of protein antigens present in mycobacterial culture filtrates and recognized by monoclonal antibodies directed against the Mycobacterium bovis BCG antigen 85 complex
7. Mapping of TH1 helper T-cell epitopes on major secreted mycobacterial antigen 85A in mice infected with live Mycobacterium bovis BCG
8. Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope
9. Enhanced production of recombinant Mycobacterium tuberculosis antigens in Escherichia coli by replacement of low-usage codons
10. The novel fibronectin-binding motif and key residues of mycobacteria
11. Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines