Synthesis and antituberculosis activity of C-phosphonate analogues of decaprenolphosphoarabinose, a key intermediate in the biosynthesis of mycobacterial arabinogalactan and lipoarabinomannan

Journal of Organic Chemistry

Volumn 67, Issue 25, 2002, Pages 8862-8870

  Centrone, Charla A ^a   Lowary, Todd L ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITUBERCULOSIS ACTIVITY;

BACTERIA; BIOSYNTHESIS; CELLS; DISEASES; ENZYMES; ESTERS; OLEFINS; PATHOLOGY;

POLYSACCHARIDES;

ALKENE; ARABINOGALACTAN; ARABINOSE DERIVATIVE; DECAPRENOLPHOSPHOARABINOSE DERIVATIVE; IMIDE; LIPOARABINOMANNAN; PHOSPHONIC ACID DERIVATIVE; POLYSACCHARIDE; TRANSFERASE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; ARABINOSYLTRANSFERASE; GALACTAN; GLYCOSYLTRANSFERASE; LIPOPOLYSACCHARIDE;

ANTIBACTERIAL ACTIVITY; ARTICLE; BIOSYNTHESIS; CELL WALL; DRUG STRUCTURE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; CARBOHYDRATE ANALYSIS; CATALYSIS; CHEMICAL STRUCTURE; CYCLIZATION; METABOLISM; MICROBIOLOGICAL EXAMINATION; SYNTHESIS;

ANTITUBERCULAR AGENTS; CARBOHYDRATE SEQUENCE; CATALYSIS; CYCLIZATION; GALACTANS; LIPOPOLYSACCHARIDES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; PENTOSYLTRANSFERASES; PHOSPHONIC ACIDS;

EID: 0037073950     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo026247r     Document Type: Article

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