Novel pyridazino[4,3-b]indoles with dual inhibitory activity against Mycobacterium tuberculosis and monoamine oxidase

Journal of Medicinal Chemistry

Volumn 47, Issue 13, 2004, Pages 3455-3461

  Velezheva, Valeriya S ^a   Brennan, Patrick J ^b   Marshakov, Vladimir Yu ^b   Gusev, Dmitrij V ^b   Lisichkina, Inessa N ^b   Peregudov, Alexander S ^b   Tchernousova, Larisa N ^c   Smirnova, Tatiana G ^c   Andreevskaya, Sofia N ^c   Medvedev, Alexei E ^c  

^a A N NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS   (Russian Federation)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ISONIAZID; MONOAMINE OXIDASE INHIBITOR; PYRIDAZINO[4,3 B]INDOLE; RIFAMPICIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATION; RAT; REDUCTION; TUBERCULOSIS;

ANIMALS; ANTITUBERCULAR AGENTS; INDOLES; MITOCHONDRIA, LIVER; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; MYCOBACTERIUM TUBERCULOSIS; PYRIDAZINES; RATS;

EID: 2942550559     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030479g     Document Type: Article

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