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Volumn 184, Issue 1-2, 2007, Pages 17-26

Neurodegeneration in autoimmune demyelination: Recent mechanistic insights reveal novel therapeutic targets

Author keywords

EAE; EGCG; HMG CoA reductase; MS; Neuronal damage; TRAIL

Indexed keywords

EPIGALLOCATECHIN GALLATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 33847635657     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2006.11.026     Document Type: Review
Times cited : (39)

References (130)
  • 1
    • 0037455718 scopus 로고    scopus 로고
    • Inhibition of ultraviolet B-mediated activation of nuclear factor kappaB in normal human epidermal keratinocytes by green tea constituent (-)-epigallocatechin-3-gallate
    • Afaq F., Adhami V.M., Ahmad N., and Mukhtar H. Inhibition of ultraviolet B-mediated activation of nuclear factor kappaB in normal human epidermal keratinocytes by green tea constituent (-)-epigallocatechin-3-gallate. Oncogene 22 (2003) 1035-1044
    • (2003) Oncogene , vol.22 , pp. 1035-1044
    • Afaq, F.1    Adhami, V.M.2    Ahmad, N.3    Mukhtar, H.4
  • 2
    • 0031444312 scopus 로고    scopus 로고
    • Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells
    • Ahmad N., Feyes D.K., Nieminen A.L., Agarwal R., and Mukhtar H. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J. Natl. Cancer Inst. 89 (1997) 1881-1886
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 1881-1886
    • Ahmad, N.1    Feyes, D.K.2    Nieminen, A.L.3    Agarwal, R.4    Mukhtar, H.5
  • 6
    • 33745906831 scopus 로고    scopus 로고
    • Death ligands and autoimmune demyelination
    • Aktas O., Prozorovski T., and Zipp F. Death ligands and autoimmune demyelination. Neuroscientist 12 (2006) 305-316
    • (2006) Neuroscientist , vol.12 , pp. 305-316
    • Aktas, O.1    Prozorovski, T.2    Zipp, F.3
  • 7
    • 0035806626 scopus 로고    scopus 로고
    • Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study
    • Albert M.A., Danielson E., Rifai N., and Ridker P.M. Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study. JAMA 286 (2001) 64-70
    • (2001) JAMA , vol.286 , pp. 64-70
    • Albert, M.A.1    Danielson, E.2    Rifai, N.3    Ridker, P.M.4
  • 9
    • 0035198891 scopus 로고    scopus 로고
    • N-acetylaspartate: usefulness as an indicator of viable neuronal tissue
    • Arnold D.L., De Stefano N., Matthews P.M., and Trapp B.D. N-acetylaspartate: usefulness as an indicator of viable neuronal tissue. Ann. Neurol. 50 (2001) 823-825
    • (2001) Ann. Neurol. , vol.50 , pp. 823-825
    • Arnold, D.L.1    De Stefano, N.2    Matthews, P.M.3    Trapp, B.D.4
  • 12
    • 27144432088 scopus 로고    scopus 로고
    • Failed central nervous system regeneration: a downside of immune privilege?
    • Bechmann I. Failed central nervous system regeneration: a downside of immune privilege?. Neuromolecular Med. 7 (2005) 217-228
    • (2005) Neuromolecular Med. , vol.7 , pp. 217-228
    • Bechmann, I.1
  • 14
    • 0033786776 scopus 로고    scopus 로고
    • Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand
    • Bielekova B., Goodwin B., Richert N., Cortese I., Kondo T., Afshar G., Gran B., Eaton J., Antel J., Frank J.A., McFarland H.F., and Martin R. Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand. Nat. Med. 6 (2000) 1167-1175
    • (2000) Nat. Med. , vol.6 , pp. 1167-1175
    • Bielekova, B.1    Goodwin, B.2    Richert, N.3    Cortese, I.4    Kondo, T.5    Afshar, G.6    Gran, B.7    Eaton, J.8    Antel, J.9    Frank, J.A.10    McFarland, H.F.11    Martin, R.12
  • 15
    • 0034026912 scopus 로고    scopus 로고
    • Acute axonal injury in multiple sclerosis:correlation with demyelination and inflammation
    • Bitsch A., Schuchardt J., Bunkowski S., Kuhlmann T., and Brück W. Acute axonal injury in multiple sclerosis:correlation with demyelination and inflammation. Brain 123 (2000) 1174-1183
    • (2000) Brain , vol.123 , pp. 1174-1183
    • Bitsch, A.1    Schuchardt, J.2    Bunkowski, S.3    Kuhlmann, T.4    Brück, W.5
  • 16
    • 0037441487 scopus 로고    scopus 로고
    • Axonal loss in the pathology of MS: consequences for understanding the progressive phase of the disease
    • Bjartmar C., Wujek J.R., and Trapp B.D. Axonal loss in the pathology of MS: consequences for understanding the progressive phase of the disease. J. Neurol. Sci. 206 (2003) 165-171
    • (2003) J. Neurol. Sci. , vol.206 , pp. 165-171
    • Bjartmar, C.1    Wujek, J.R.2    Trapp, B.D.3
  • 17
    • 0042123685 scopus 로고    scopus 로고
    • Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration
    • Bo L., Vedeler C.A., Nyland H., Trapp B.D., and Mork S.J. Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration. Mult. Scler. 9 (2003) 323-331
    • (2003) Mult. Scler. , vol.9 , pp. 323-331
    • Bo, L.1    Vedeler, C.A.2    Nyland, H.3    Trapp, B.D.4    Mork, S.J.5
  • 19
    • 33645230364 scopus 로고    scopus 로고
    • Direct neuronal effects of statins
    • Bosel J., and Endres M. Direct neuronal effects of statins. Nervenarzt 77 (2006) 289-293
    • (2006) Nervenarzt , vol.77 , pp. 289-293
    • Bosel, J.1    Endres, M.2
  • 21
    • 0025770041 scopus 로고
    • Concentrations of pravastatin and lovastatin in cerebrospinal fluid in healthy subjects
    • Botti R.E., Triscari J., Pan H.Y., and Zayat J. Concentrations of pravastatin and lovastatin in cerebrospinal fluid in healthy subjects. Clin. Neuropharmacol. 14 (1991) 256-261
    • (1991) Clin. Neuropharmacol. , vol.14 , pp. 256-261
    • Botti, R.E.1    Triscari, J.2    Pan, H.Y.3    Zayat, J.4
  • 22
    • 0033621780 scopus 로고    scopus 로고
    • p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes
    • Boussiotis V.A., Freeman G.J., Taylor P.A., Berezovskaya A., Grass I., Blazar B.R., and Nadler L.M. p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes. Nat. Med. 6 (2000) 290-297
    • (2000) Nat. Med. , vol.6 , pp. 290-297
    • Boussiotis, V.A.1    Freeman, G.J.2    Taylor, P.A.3    Berezovskaya, A.4    Grass, I.5    Blazar, B.R.6    Nadler, L.M.7
  • 24
    • 0030056639 scopus 로고    scopus 로고
    • Mechanisms of immune injury in multiple sclerosis
    • Brosnan C.F., and Raine C.S. Mechanisms of immune injury in multiple sclerosis. Brain Pathol. 6 (1996) 243-257
    • (1996) Brain Pathol. , vol.6 , pp. 243-257
    • Brosnan, C.F.1    Raine, C.S.2
  • 25
    • 0242585496 scopus 로고    scopus 로고
    • Neutralization of TRAIL death pathway protects human neuronal cell line from beta-amyloid toxicity
    • Cantarella G., Uberti D., Carsana T., Lombardo G., Bernardini R., and Memo M. Neutralization of TRAIL death pathway protects human neuronal cell line from beta-amyloid toxicity. Cell Death Differ. 10 (2003) 134-141
    • (2003) Cell Death Differ. , vol.10 , pp. 134-141
    • Cantarella, G.1    Uberti, D.2    Carsana, T.3    Lombardo, G.4    Bernardini, R.5    Memo, M.6
  • 26
    • 21944448962 scopus 로고    scopus 로고
    • Short-lived plasma blasts are the main B cell effector subset during the course of multiple sclerosis
    • Cepok S., Rosche B., Grummel V., Vogel F., Zhou D., Sayn J., Sommer N., Hartung H.P., and Hemmer B. Short-lived plasma blasts are the main B cell effector subset during the course of multiple sclerosis. Brain 128 (2005) 1667-1676
    • (2005) Brain , vol.128 , pp. 1667-1676
    • Cepok, S.1    Rosche, B.2    Grummel, V.3    Vogel, F.4    Zhou, D.5    Sayn, J.6    Sommer, N.7    Hartung, H.P.8    Hemmer, B.9
  • 28
    • 32144454172 scopus 로고    scopus 로고
    • The many roles of chemokines and chemokine receptors in inflammation
    • Charo I.F., and Ransohoff R.M. The many roles of chemokines and chemokine receptors in inflammation. N. Engl. J. Med. 354 (2006) 610-621
    • (2006) N. Engl. J. Med. , vol.354 , pp. 610-621
    • Charo, I.F.1    Ransohoff, R.M.2
  • 30
    • 0036746177 scopus 로고    scopus 로고
    • Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate
    • Choi J.Y., Park C.S., Kim D.J., Cho M.H., Jin B.K., Pie J.E., and Chung W.G. Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate. Neurotoxicology 23 (2002) 367-374
    • (2002) Neurotoxicology , vol.23 , pp. 367-374
    • Choi, J.Y.1    Park, C.S.2    Kim, D.J.3    Cho, M.H.4    Jin, B.K.5    Pie, J.E.6    Chung, W.G.7
  • 31
    • 0141751841 scopus 로고    scopus 로고
    • Tea and cancer prevention: studies in animals and humans
    • Chung F.L., Schwartz J., Herzog C.R., and Yang Y.M. Tea and cancer prevention: studies in animals and humans. J. Nutr. 133 (2003) 3268S-3274S
    • (2003) J. Nutr. , vol.133
    • Chung, F.L.1    Schwartz, J.2    Herzog, C.R.3    Yang, Y.M.4
  • 34
    • 0037062481 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy
    • Danesh F.R., Sadeghi M.M., Amro N., Philips C., Zeng L., Lin S., Sahai A., and Kanwar Y.S. 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 8301-8305
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 8301-8305
    • Danesh, F.R.1    Sadeghi, M.M.2    Amro, N.3    Philips, C.4    Zeng, L.5    Lin, S.6    Sahai, A.7    Kanwar, Y.S.8
  • 35
    • 84974201150 scopus 로고
    • The histology of disseminated sclerosis
    • Dawson J. The histology of disseminated sclerosis. Trans. R. Soc. Edinb. 50 (1916) 517-740
    • (1916) Trans. R. Soc. Edinb. , vol.50 , pp. 517-740
    • Dawson, J.1
  • 37
    • 0344737604 scopus 로고    scopus 로고
    • Activation of microglial poly(ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage
    • Diestel A., Aktas O., Hackel D., Hake I., Meier S., Raine C.S., Nitsch R., Zipp F., and Ullrich O. Activation of microglial poly(ADP-ribose)-polymerase-1 by cholesterol breakdown products during neuroinflammation: a link between demyelination and neuronal damage. J. Exp. Med. 198 (2003) 1729-1740
    • (2003) J. Exp. Med. , vol.198 , pp. 1729-1740
    • Diestel, A.1    Aktas, O.2    Hackel, D.3    Hake, I.4    Meier, S.5    Raine, C.S.6    Nitsch, R.7    Zipp, F.8    Ullrich, O.9
  • 38
  • 39
    • 0037085319 scopus 로고    scopus 로고
    • Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain
    • Dörr J., Bechmann I., Waiczies S., Aktas O., Walczak H., Krammer P.H., Nitsch R., and Zipp F. Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain. J. Neurosci. 22 (2002) RC209
    • (2002) J. Neurosci. , vol.22
    • Dörr, J.1    Bechmann, I.2    Waiczies, S.3    Aktas, O.4    Walczak, H.5    Krammer, P.H.6    Nitsch, R.7    Zipp, F.8
  • 40
  • 42
    • 0242509835 scopus 로고    scopus 로고
    • Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes
    • Ehrlich S., Infante-Duarte C., Seeger B., and Zipp F. Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes. Cytokine 24 (2003) 244-253
    • (2003) Cytokine , vol.24 , pp. 244-253
    • Ehrlich, S.1    Infante-Duarte, C.2    Seeger, B.3    Zipp, F.4
  • 43
    • 33748996772 scopus 로고    scopus 로고
    • Discontinuation of statin treatment in stroke patients
    • Endres M., and Laufs U. Discontinuation of statin treatment in stroke patients. Stroke 37 (2006) 2640-2643
    • (2006) Stroke , vol.37 , pp. 2640-2643
    • Endres, M.1    Laufs, U.2
  • 44
    • 0036892110 scopus 로고    scopus 로고
    • Epileptic seizures, cranial neuralgias and paroxysmal symptoms in remitting and progressive multiple sclerosis
    • Eriksson M., Ben Menachem E., and Andersen O. Epileptic seizures, cranial neuralgias and paroxysmal symptoms in remitting and progressive multiple sclerosis. Mult. Scler. 8 (2002) 495-499
    • (2002) Mult. Scler. , vol.8 , pp. 495-499
    • Eriksson, M.1    Ben Menachem, E.2    Andersen, O.3
  • 46
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • Ferguson B., Matyszak M.K., Esiri M.M., and Perry V.H. Axonal damage in acute multiple sclerosis lesions. Brain 120 (1997) 393-399
    • (1997) Brain , vol.120 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 47
    • 24644435506 scopus 로고    scopus 로고
    • Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease
    • Frenkel D., Maron R., Burt D.S., and Weiner H.L. Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease. J. Clin. Invest. 115 (2005) 2423-2433
    • (2005) J. Clin. Invest. , vol.115 , pp. 2423-2433
    • Frenkel, D.1    Maron, R.2    Burt, D.S.3    Weiner, H.L.4
  • 48
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis-the plaque and its pathogenesis
    • Frohman E.M., Racke M.K., and Raine C.S. Multiple sclerosis-the plaque and its pathogenesis. N. Engl. J. Med. 354 (2006) 942-955
    • (2006) N. Engl. J. Med. , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 49
    • 0036341291 scopus 로고    scopus 로고
    • Smac agonists sensitize for Apo2L/TRAIL-or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
    • Fulda S., Wick W., Weller M., and Debatin K.-M. Smac agonists sensitize for Apo2L/TRAIL-or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo. Nat. Med. 8 (2002) 808-815
    • (2002) Nat. Med. , vol.8 , pp. 808-815
    • Fulda, S.1    Wick, W.2    Weller, M.3    Debatin, K.-M.4
  • 50
    • 0035114219 scopus 로고    scopus 로고
    • Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition
    • Garcia-Roman N., Alvarez A.M., Toro M.J., Montes A., and Lorenzo M.J. Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition. Mol. Cell. Neurosci. 17 (2001) 329-341
    • (2001) Mol. Cell. Neurosci. , vol.17 , pp. 329-341
    • Garcia-Roman, N.1    Alvarez, A.M.2    Toro, M.J.3    Montes, A.4    Lorenzo, M.J.5
  • 51
    • 0037530542 scopus 로고    scopus 로고
    • Vulnerability of human neurons to T cell-mediated cytotoxicity
    • Giuliani F., Goodyer C.G., Antel J.P., and Yong V.W. Vulnerability of human neurons to T cell-mediated cytotoxicity. J. Immunol. 171 (2003) 368-379
    • (2003) J. Immunol. , vol.171 , pp. 368-379
    • Giuliani, F.1    Goodyer, C.G.2    Antel, J.P.3    Yong, V.W.4
  • 52
    • 33746729791 scopus 로고    scopus 로고
    • Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
    • Gold R., Linington C., and Lassmann H. Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain 129 Pt 8 (2006) 1953-1971
    • (2006) Brain , vol.129 , Issue.PART 8 , pp. 1953-1971
    • Gold, R.1    Linington, C.2    Lassmann, H.3
  • 53
    • 0038322504 scopus 로고    scopus 로고
    • Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis
    • Greenwood J., Walters C.E., Pryce G., Kanuga N., Beraud E., Baker D., and Adamson P. Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis. FASEB J. 17 (2003) 905-907
    • (2003) FASEB J. , vol.17 , pp. 905-907
    • Greenwood, J.1    Walters, C.E.2    Pryce, G.3    Kanuga, N.4    Beraud, E.5    Baker, D.6    Adamson, P.7
  • 54
    • 33646354412 scopus 로고    scopus 로고
    • Statin therapy and autoimmune disease: from protein prenylation to immunomodulation
    • Greenwood J., Steinman L., and Zamvil S.S. Statin therapy and autoimmune disease: from protein prenylation to immunomodulation. Nat. Rev. Immunol. 6 (2006) 358-370
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 358-370
    • Greenwood, J.1    Steinman, L.2    Zamvil, S.S.3
  • 56
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial
    • Group THPSC. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 360 (2002) 7-22
    • (2002) Lancet , vol.360 , pp. 7-22
    • Group THPSC1
  • 57
    • 0031881755 scopus 로고    scopus 로고
    • Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors
    • Hamelin B.A., and Turgeon J. Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors. Trends Pharmacol. Sci. 19 (1998) 26-37
    • (1998) Trends Pharmacol. Sci. , vol.19 , pp. 26-37
    • Hamelin, B.A.1    Turgeon, J.2
  • 59
    • 0029670477 scopus 로고    scopus 로고
    • Translational control of p27Kip1 accumulation during the cell cycle
    • Hengst L., and Reed S.I. Translational control of p27Kip1 accumulation during the cell cycle. Science 271 (1996) 1861-1864
    • (1996) Science , vol.271 , pp. 1861-1864
    • Hengst, L.1    Reed, S.I.2
  • 62
    • 0035863835 scopus 로고    scopus 로고
    • Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis
    • Hilliard B., Wilmen A., Seidel C., Liu T.-S.L., Göke R., and Chen Y. Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis. J. Immunol. 166 (2001) 1314-1319
    • (2001) J. Immunol. , vol.166 , pp. 1314-1319
    • Hilliard, B.1    Wilmen, A.2    Seidel, C.3    Liu, T.-S.L.4    Göke, R.5    Chen, Y.6
  • 64
    • 0029286303 scopus 로고
    • Control of signal transduction and morphogenesis by Ras
    • Hughes D.A. Control of signal transduction and morphogenesis by Ras. Semin. Cell. Biol. 6 (1995) 89-94
    • (1995) Semin. Cell. Biol. , vol.6 , pp. 89-94
    • Hughes, D.A.1
  • 65
    • 1842608971 scopus 로고    scopus 로고
    • Indirect evidence for early widespread gray matter involvement in relapsing-remitting multiple sclerosis
    • Inglese M., Ge Y., Filippi M., Falini A., Grossman R.I., and Gonen O. Indirect evidence for early widespread gray matter involvement in relapsing-remitting multiple sclerosis. Neuroimage 21 (2004) 1825-1829
    • (2004) Neuroimage , vol.21 , pp. 1825-1829
    • Inglese, M.1    Ge, Y.2    Filippi, M.3    Falini, A.4    Grossman, R.I.5    Gonen, O.6
  • 67
    • 0026647293 scopus 로고
    • Role of CD8+ T cells in murine experimental allergic encephalomyelitis
    • Jiang H., Zhang S.I., and Pernis B. Role of CD8+ T cells in murine experimental allergic encephalomyelitis. Science 256 (1992) 1213-1215
    • (1992) Science , vol.256 , pp. 1213-1215
    • Jiang, H.1    Zhang, S.I.2    Pernis, B.3
  • 69
    • 0032740780 scopus 로고    scopus 로고
    • Prevention of UVB-induced immunosuppression in mice by the green tea polyphenol (-)-epigallocatechin-3-gallate may be associated with alterations in IL-10 and IL-12 production
    • Katiyar S.K., Challa A., McCormick T.S., Cooper K.D., and Mukhtar H. Prevention of UVB-induced immunosuppression in mice by the green tea polyphenol (-)-epigallocatechin-3-gallate may be associated with alterations in IL-10 and IL-12 production. Carcinogenesis 20 (1999) 2117-2124
    • (1999) Carcinogenesis , vol.20 , pp. 2117-2124
    • Katiyar, S.K.1    Challa, A.2    McCormick, T.S.3    Cooper, K.D.4    Mukhtar, H.5
  • 71
    • 0033870097 scopus 로고    scopus 로고
    • Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions
    • Kornek B., Storch M.K., Weissert R., Wallstroem E., Stefferl A., Olsson T., Linington C., Schmidbauer M., and Lassmann H. Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions. Am. J. Pathol. 157 (2000) 267-276
    • (2000) Am. J. Pathol. , vol.157 , pp. 267-276
    • Kornek, B.1    Storch, M.K.2    Weissert, R.3    Wallstroem, E.4    Stefferl, A.5    Olsson, T.6    Linington, C.7    Schmidbauer, M.8    Lassmann, H.9
  • 73
    • 0034533147 scopus 로고    scopus 로고
    • Statins as a newly recognized type of immunomodulator
    • Kwak B., Mulhaupt F., Myit S., and Mach F. Statins as a newly recognized type of immunomodulator. Nat. Med. 6 (2000) 1399-1402
    • (2000) Nat. Med. , vol.6 , pp. 1399-1402
    • Kwak, B.1    Mulhaupt, F.2    Myit, S.3    Mach, F.4
  • 74
    • 0034733810 scopus 로고    scopus 로고
    • Protective effects of the green tea polyphenol (-)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils
    • Lee S., Suh S., and Kim S. Protective effects of the green tea polyphenol (-)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils. Neurosci. Lett. 287 (2000) 191-194
    • (2000) Neurosci. Lett. , vol.287 , pp. 191-194
    • Lee, S.1    Suh, S.2    Kim, S.3
  • 75
  • 76
    • 0034851553 scopus 로고    scopus 로고
    • Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration
    • Levites Y., Weinreb O., Maor G., Youdim M.B., and Mandel S. Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration. J. Neurochem. 78 (2001) 1073-1082
    • (2001) J. Neurochem. , vol.78 , pp. 1073-1082
    • Levites, Y.1    Weinreb, O.2    Maor, G.3    Youdim, M.B.4    Mandel, S.5
  • 77
    • 0033213758 scopus 로고    scopus 로고
    • Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate
    • Liang Y.C., Lin-Shiau S.Y., Chen C.F., and Lin J.K. Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate. J. Cell Biochem. 75 (1999) 1-12
    • (1999) J. Cell Biochem. , vol.75 , pp. 1-12
    • Liang, Y.C.1    Lin-Shiau, S.Y.2    Chen, C.F.3    Lin, J.K.4
  • 78
    • 0036322869 scopus 로고    scopus 로고
    • Isoprenoids as mediators of the biological effects of statins
    • Liao J.K. Isoprenoids as mediators of the biological effects of statins. J. Clin. Invest. 110 (2002) 285-288
    • (2002) J. Clin. Invest. , vol.110 , pp. 285-288
    • Liao, J.K.1
  • 79
    • 20444394379 scopus 로고    scopus 로고
    • Mechanisms of axonal degeneration in EAE-lessons from CNTF and MHC I knockout mice
    • Linker R.A., Sendtner M., and Gold R. Mechanisms of axonal degeneration in EAE-lessons from CNTF and MHC I knockout mice. J. Neurol Sci. 233 (2005) 167-172
    • (2005) J. Neurol Sci. , vol.233 , pp. 167-172
    • Linker, R.A.1    Sendtner, M.2    Gold, R.3
  • 80
    • 0037126058 scopus 로고    scopus 로고
    • Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice
    • Lu Y.P., Lou Y.R., Xie J.G., Peng Q.Y., Liao J., Yang C.S., Huang M.T., and Conney A.H. Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 12455-12460
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 12455-12460
    • Lu, Y.P.1    Lou, Y.R.2    Xie, J.G.3    Peng, Q.Y.4    Liao, J.5    Yang, C.S.6    Huang, M.T.7    Conney, A.H.8
  • 81
    • 0037094010 scopus 로고    scopus 로고
    • Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells
    • Lünemann J.D., Waiczies S., Ehrlich S., Wendling U., Seeger B., Kamradt T., and Zipp F. Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells. J. Immunol. 168 (2002) 4881-4888
    • (2002) J. Immunol. , vol.168 , pp. 4881-4888
    • Lünemann, J.D.1    Waiczies, S.2    Ehrlich, S.3    Wendling, U.4    Seeger, B.5    Kamradt, T.6    Zipp, F.7
  • 82
    • 0026751291 scopus 로고
    • Elevated secretion of reactive nitrogen and oxygen intermediates by inflammatory leukocytes in hyperacute experimental autoimmune encephalomyelitis: enhancement by the soluble products of encephalitogenic T cells
    • MacMicking J.D., Willenborg D.O., Weidemann M.J., Rockett K.A., and Cowden W.B. Elevated secretion of reactive nitrogen and oxygen intermediates by inflammatory leukocytes in hyperacute experimental autoimmune encephalomyelitis: enhancement by the soluble products of encephalitogenic T cells. J. Exp. Med. 176 (1992) 303-307
    • (1992) J. Exp. Med. , vol.176 , pp. 303-307
    • MacMicking, J.D.1    Willenborg, D.O.2    Weidemann, M.J.3    Rockett, K.A.4    Cowden, W.B.5
  • 83
    • 0033984436 scopus 로고    scopus 로고
    • Current perspectives on statins
    • Maron D.J., Fazio S., and Linton M.F. Current perspectives on statins. Circulation 101 (2000) 207-213
    • (2000) Circulation , vol.101 , pp. 207-213
    • Maron, D.J.1    Fazio, S.2    Linton, M.F.3
  • 84
    • 0033562658 scopus 로고    scopus 로고
    • CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons
    • Martin-Villalba A., Herr I., Jeremias I., Hahne M., Brandt R., Vogel J., Schenkel J., Herdegen T., and Debatin K.-M. CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons. J. Neurosci. 19 (1999) 3809-3817
    • (1999) J. Neurosci. , vol.19 , pp. 3809-3817
    • Martin-Villalba, A.1    Herr, I.2    Jeremias, I.3    Hahne, M.4    Brandt, R.5    Vogel, J.6    Schenkel, J.7    Herdegen, T.8    Debatin, K.-M.9
  • 86
    • 0037235059 scopus 로고    scopus 로고
    • Blockade of HMG-CoA reductase activity causes changes in microtubule-stabilizing protein tau via suppression of geranylgeranylpyrophosphate formation: implications for Alzheimer's disease
    • Meske V., Albert F., Richter D., Schwarze J., and Ohm T.G. Blockade of HMG-CoA reductase activity causes changes in microtubule-stabilizing protein tau via suppression of geranylgeranylpyrophosphate formation: implications for Alzheimer's disease. Eur. J. Neurosci. 17 (2003) 93-102
    • (2003) Eur. J. Neurosci. , vol.17 , pp. 93-102
    • Meske, V.1    Albert, F.2    Richter, D.3    Schwarze, J.4    Ohm, T.G.5
  • 89
    • 0033391076 scopus 로고    scopus 로고
    • Green tea in chemoprevention of cancer
    • Mukhtar H., and Ahmad N. Green tea in chemoprevention of cancer. Toxicol. Sci. 52 (1999) 111-117
    • (1999) Toxicol. Sci. , vol.52 , pp. 111-117
    • Mukhtar, H.1    Ahmad, N.2
  • 91
    • 0035918278 scopus 로고    scopus 로고
    • Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo
    • Nam S., Smith D.M., and Dou Q.P. Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo. J. Biol. Chem. 276 (2001) 13322-13330
    • (2001) J. Biol. Chem. , vol.276 , pp. 13322-13330
    • Nam, S.1    Smith, D.M.2    Dou, Q.P.3
  • 93
    • 2442589337 scopus 로고    scopus 로고
    • Are statins a treatment option for multiple sclerosis?
    • Neuhaus O., Stuve O., Zamvil S.S., and Hartung H.P. Are statins a treatment option for multiple sclerosis?. Lancet Neurol 3 (2004) 369-371
    • (2004) Lancet Neurol , vol.3 , pp. 369-371
    • Neuhaus, O.1    Stuve, O.2    Zamvil, S.S.3    Hartung, H.P.4
  • 94
    • 0036602982 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases
    • Neumann H., Medana I.M., Bauer J., and Lassmann H. Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases. Trends Neurosci. 25 (2002) 313-319
    • (2002) Trends Neurosci. , vol.25 , pp. 313-319
    • Neumann, H.1    Medana, I.M.2    Bauer, J.3    Lassmann, H.4
  • 95
    • 0034596514 scopus 로고    scopus 로고
    • Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)
    • Nitsch R., Bechmann I., Deisz R.A., Haas D., Lehmann T.N., Wendling U., and Zipp F. Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL). Lancet 356 (2000) 827-828
    • (2000) Lancet , vol.356 , pp. 827-828
    • Nitsch, R.1    Bechmann, I.2    Deisz, R.A.3    Haas, D.4    Lehmann, T.N.5    Wendling, U.6    Zipp, F.7
  • 96
    • 1542267742 scopus 로고    scopus 로고
    • Direct impact of T cells on neurons revealed by two-photon microscopy in living brain tissue
    • Nitsch R., Pohl E.E., Smorodchenko A., Infante-Duarte C., Aktas O., and Zipp F. Direct impact of T cells on neurons revealed by two-photon microscopy in living brain tissue. J. Neurosci. 24 (2004) 2458-2464
    • (2004) J. Neurosci. , vol.24 , pp. 2458-2464
    • Nitsch, R.1    Pohl, E.E.2    Smorodchenko, A.3    Infante-Duarte, C.4    Aktas, O.5    Zipp, F.6
  • 98
    • 0034528569 scopus 로고    scopus 로고
    • Immunomodulation: a new role for statins?
    • Palinski W. Immunomodulation: a new role for statins?. Nat. Med. 6 (2000) 1311-1312
    • (2000) Nat. Med. , vol.6 , pp. 1311-1312
    • Palinski, W.1
  • 99
    • 0034842126 scopus 로고    scopus 로고
    • Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions
    • Peterson J.W., Bo L., Mork S., Chang A., and Trapp B.D. Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann. Neurol. 50 (2001) 389-400
    • (2001) Ann. Neurol. , vol.50 , pp. 389-400
    • Peterson, J.W.1    Bo, L.2    Mork, S.3    Chang, A.4    Trapp, B.D.5
  • 100
    • 0033958462 scopus 로고    scopus 로고
    • Glutamate excitotoxicity in a model of multiple sclerosis
    • Pitt D., Werner P., and Raine C.S. Glutamate excitotoxicity in a model of multiple sclerosis. Nat. Med. 6 (2000) 67-70
    • (2000) Nat. Med. , vol.6 , pp. 67-70
    • Pitt, D.1    Werner, P.2    Raine, C.S.3
  • 101
    • 33645854917 scopus 로고    scopus 로고
    • The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons
    • Pooler A.M., Xi S.C., and Wurtman R.J. The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons. J. Neurochem. 97 (2006) 716-723
    • (2006) J. Neurochem. , vol.97 , pp. 716-723
    • Pooler, A.M.1    Xi, S.C.2    Wurtman, R.J.3
  • 102
    • 0025999293 scopus 로고
    • ras isoprenylation is required for ras-induced but not for NGF-induced neuronal differentiation of PC12 cells
    • Qiu M.S., Pitts A.F., Winters T.R., and Green S.H. ras isoprenylation is required for ras-induced but not for NGF-induced neuronal differentiation of PC12 cells. J. Cell Biol. 115 (1991) 795-808
    • (1991) J. Cell Biol. , vol.115 , pp. 795-808
    • Qiu, M.S.1    Pitts, A.F.2    Winters, T.R.3    Green, S.H.4
  • 104
    • 0035963529 scopus 로고    scopus 로고
    • Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events
    • Ridker P.M., Rifai N., Clearfield M., Downs J.R., Weis S.E., Miles J.S., and Gotto A.M. Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events. N. Engl. J. Med. 344 (2001) 1959-1965
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1959-1965
    • Ridker, P.M.1    Rifai, N.2    Clearfield, M.3    Downs, J.R.4    Weis, S.E.5    Miles, J.S.6    Gotto, A.M.7
  • 106
    • 0028281788 scopus 로고
    • In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors
    • Saheki A., Terasaki T., Tamai I., and Tsuji A. In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors. Pharm. Res. 11 (1994) 305-311
    • (1994) Pharm. Res. , vol.11 , pp. 305-311
    • Saheki, A.1    Terasaki, T.2    Tamai, I.3    Tsuji, A.4
  • 107
    • 1842510494 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis
    • Schulz J.G., Bosel J., Stoeckel M., Megow D., Dirnagl U., and Endres M. HMG-CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis. J. Neurochem. 89 (2004) 24-32
    • (2004) J. Neurochem. , vol.89 , pp. 24-32
    • Schulz, J.G.1    Bosel, J.2    Stoeckel, M.3    Megow, D.4    Dirnagl, U.5    Endres, M.6
  • 108
    • 0037420492 scopus 로고    scopus 로고
    • Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial
    • Sever P.S., Dahlof B., Poulter N.R., Wedel H., Beevers G., Caulfield M., Collins R., Kjeldsen S.E., Kristinsson A., McInnes G.T., Mehlsen J., Nieminen M., O'Brien E., and Ostergren J. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 361 (2003) 1149-1158
    • (2003) Lancet , vol.361 , pp. 1149-1158
    • Sever, P.S.1    Dahlof, B.2    Poulter, N.R.3    Wedel, H.4    Beevers, G.5    Caulfield, M.6    Collins, R.7    Kjeldsen, S.E.8    Kristinsson, A.9    McInnes, G.T.10    Mehlsen, J.11    Nieminen, M.12    O'Brien, E.13    Ostergren, J.14
  • 110
    • 0035067635 scopus 로고    scopus 로고
    • Electrically active axons degenerate when exposed to nitric oxide
    • Smith K.J., Kapoor R., Hall S.M., and Davies M. Electrically active axons degenerate when exposed to nitric oxide. Ann. Neurol. 49 (2001) 470-476
    • (2001) Ann. Neurol. , vol.49 , pp. 470-476
    • Smith, K.J.1    Kapoor, R.2    Hall, S.M.3    Davies, M.4
  • 111
    • 0033963231 scopus 로고    scopus 로고
    • Autoimmune encephalomyelitis ameliorated by AMPA antagonists
    • Smith T., Groom A., Zhu B., and Turski L. Autoimmune encephalomyelitis ameliorated by AMPA antagonists. Nat. Med. 6 (2000) 62-66
    • (2000) Nat. Med. , vol.6 , pp. 62-66
    • Smith, T.1    Groom, A.2    Zhu, B.3    Turski, L.4
  • 113
    • 0033538533 scopus 로고    scopus 로고
    • Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin
    • Stanislaus R., Pahana K., Singhb A.K., and Singh I. Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin. Neurosci. Lett. 269 (1999) 71-74
    • (1999) Neurosci. Lett. , vol.269 , pp. 71-74
    • Stanislaus, R.1    Pahana, K.2    Singhb, A.K.3    Singh, I.4
  • 114
    • 0035888090 scopus 로고    scopus 로고
    • Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis
    • Stanislaus R., Singh A.K., and Singh I. Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis. J. Neurosci. Res. 66 (2001) 155-162
    • (2001) J. Neurosci. Res. , vol.66 , pp. 155-162
    • Stanislaus, R.1    Singh, A.K.2    Singh, I.3
  • 115
    • 0029965137 scopus 로고    scopus 로고
    • A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry
    • Steinman L. A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry. Proc. Natl. Acad. Sci. U. S. A. 93 (2002) 2253-2256
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 2253-2256
    • Steinman, L.1
  • 116
    • 0037882036 scopus 로고    scopus 로고
    • Optic neuritis, a new variant of experimental encephalomyelitis, a durable model for all seasons, now in its seventieth year
    • Steinman L. Optic neuritis, a new variant of experimental encephalomyelitis, a durable model for all seasons, now in its seventieth year. J. Exp. Med. 197 (2003) 1065-1071
    • (2003) J. Exp. Med. , vol.197 , pp. 1065-1071
    • Steinman, L.1
  • 118
    • 0023904339 scopus 로고
    • Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T-T cell interactions
    • Sun D., Qin Y., Chluba J., Epplen J.T., and Wekerle H. Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T-T cell interactions. Nature 332 (1988) 843-845
    • (1988) Nature , vol.332 , pp. 843-845
    • Sun, D.1    Qin, Y.2    Chluba, J.3    Epplen, J.T.4    Wekerle, H.5
  • 123
    • 27744437031 scopus 로고    scopus 로고
    • Modulating T cell signaling cascades by HMG-CoA reductase inhibitors
    • Waiczies S., Prozorovski T., and Zipp F. Modulating T cell signaling cascades by HMG-CoA reductase inhibitors. Signal Transduct. 5 (2005) 231-244
    • (2005) Signal Transduct. , vol.5 , pp. 231-244
    • Waiczies, S.1    Prozorovski, T.2    Zipp, F.3
  • 124
    • 0037307981 scopus 로고    scopus 로고
    • Nitric oxide and the axonal death cascade
    • Waxman S.G. Nitric oxide and the axonal death cascade. Ann. Neurol. 53 (2003) 150-153
    • (2003) Ann. Neurol. , vol.53 , pp. 150-153
    • Waxman, S.G.1
  • 126
    • 0033772113 scopus 로고    scopus 로고
    • Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors
    • Wolozin B., Kellman W., Ruosseau P., Celesia G.G., and Siegel G. Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch. Neurol. 57 (2000) 1439-1443
    • (2000) Arch. Neurol. , vol.57 , pp. 1439-1443
    • Wolozin, B.1    Kellman, W.2    Ruosseau, P.3    Celesia, G.G.4    Siegel, G.5
  • 127
    • 0031815389 scopus 로고    scopus 로고
    • Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols
    • Yang G.Y., Liao J., Kim K., Yurkow E.J., and Yang C.S. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols. Carcinogenesis 19 (1998) 611-616
    • (1998) Carcinogenesis , vol.19 , pp. 611-616
    • Yang, G.Y.1    Liao, J.2    Kim, K.3    Yurkow, E.J.4    Yang, C.S.5
  • 128
    • 0346749450 scopus 로고    scopus 로고
    • 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect cortical neurons from excitotoxicity
    • Zacco A., Togo J., Spence K., Ellis A., Lloyd D., Furlong S., and Piser T. 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect cortical neurons from excitotoxicity. J. Neurosci. 23 (2003) 11104-11111
    • (2003) J. Neurosci. , vol.23 , pp. 11104-11111
    • Zacco, A.1    Togo, J.2    Spence, K.3    Ellis, A.4    Lloyd, D.5    Furlong, S.6    Piser, T.7
  • 129
    • 0942278990 scopus 로고    scopus 로고
    • Association between statin use and Alzheimer's disease
    • Zamrini E., McGwin G., and Roseman J.M. Association between statin use and Alzheimer's disease. Neuroepidemiology 23 (2004) 94-98
    • (2004) Neuroepidemiology , vol.23 , pp. 94-98
    • Zamrini, E.1    McGwin, G.2    Roseman, J.M.3
  • 130
    • 33747890559 scopus 로고    scopus 로고
    • Zipp, F., Aktas, O., in press. The brain as a target of inflammatory processes: common pathways link inflammatory and neurodegenerative diseases. Trends Neurosci. 29, 518-527.


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