-
1
-
-
0032934156
-
Functional roles of STAT family proteins: Lessons from knockout mice
-
Akira, S. (1999) Functional roles of STAT family proteins: lessons from knockout mice. Stem Cells 17, 138-146.
-
(1999)
Stem Cells
, vol.17
, pp. 138-146
-
-
Akira, S.1
-
2
-
-
0036138705
-
A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRL-mediated signaling pathway: Dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus
-
Aoki, N., Matsuda, T. (2002) A nuclear protein tyrosine phosphatase TC-PTP is a potential negative regulator of the PRL-mediated signaling pathway: dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus. Mol. Endocrinol. 16, 58-69.
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 58-69
-
-
Aoki, N.1
Matsuda, T.2
-
3
-
-
0036625960
-
The role of STATs in apoptosis
-
Battle, T. E., Frank, D. A. (2002) The role of STATs in apoptosis. Curr. Mol. Med. 2, 381-392.
-
(2002)
Curr. Mol. Med.
, vol.2
, pp. 381-392
-
-
Battle, T.E.1
Frank, D.A.2
-
4
-
-
0042324670
-
Interferon inducibility of STAT 1 activation and its prognostic significance in melanoma patients
-
Boudny, V., Kocak, I., Lauerova, L., Kovarik, J. (2003) Interferon inducibility of STAT 1 activation and its prognostic significance in melanoma patients. Folia Biol. (Praha) 49, 142-146.
-
(2003)
Folia Biol. (Praha)
, vol.49
, pp. 142-146
-
-
Boudny, V.1
Kocak, I.2
Lauerova, L.3
Kovarik, J.4
-
5
-
-
23044463075
-
Lack of STAT 1 phosphorylation at TYR 701 by IFNγ correlates with disease outcome in melanoma patients
-
Boudny, V., Dusek, L., Adamkova, L., Chumchalova, J., Kocak, I., Fait, V, Lauerova, L., Krejci, E., Kovarik, J. (2005) Lack of STAT 1 phosphorylation at TYR 701 by IFNγ correlates with disease outcome in melanoma patients. Neoplasma 52, 330-337.
-
(2005)
Neoplasma
, vol.52
, pp. 330-337
-
-
Boudny, V.1
Dusek, L.2
Adamkova, L.3
Chumchalova, J.4
Kocak, I.5
Fait, V.6
Lauerova, L.7
Krejci, E.8
Kovarik, J.9
-
6
-
-
0034658698
-
STATs in oncogenesis
-
Bowman, T., Garcia, R., Turkson, J., Jove, R. (2000) STATs in oncogenesis. Oncogene 19, 2474-2488.
-
(2000)
Oncogene
, vol.19
, pp. 2474-2488
-
-
Bowman, T.1
Garcia, R.2
Turkson, J.3
Jove, R.4
-
7
-
-
0030248417
-
JAKs and STATs branch out
-
Briscoe, J., Kohlhuber, F., Muller, M. (1996) JAKs and STATs branch out. Trends Cell Biol. 6, 336-340.
-
(1996)
Trends Cell Biol.
, vol.6
, pp. 336-340
-
-
Briscoe, J.1
Kohlhuber, F.2
Muller, M.3
-
8
-
-
0035142665
-
Activation of STAT proteins and growth control
-
Bromberg, J. F. (2001) Activation of STAT proteins and growth control. BioEssays 23, 161-169.
-
(2001)
BioEssays
, vol.23
, pp. 161-169
-
-
Bromberg, J.F.1
-
9
-
-
0034657336
-
The role of STATs in transcriptional control and their impact on cellular function
-
Bromberg, J., Darnell, J. E. Jr. (2000) The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19, 2468-2473.
-
(2000)
Oncogene
, vol.19
, pp. 2468-2473
-
-
Bromberg, J.1
Darnell Jr., J.E.2
-
10
-
-
0029799912
-
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon α and interferon γ
-
Bromberg, J. F., Horvath, C. M., Wen, Z., Schreiber, R. D., Darnell, J. E. Jr. (1996) Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon α and interferon γ. Proc. Natl. Acad. Sci. USA 93, 7673-7678.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7673-7678
-
-
Bromberg, J.F.1
Horvath, C.M.2
Wen, Z.3
Schreiber, R.D.4
Darnell Jr., J.E.5
-
11
-
-
0031820158
-
Epidermal growth factor-induced growth inhibition requires Stat1 activation
-
Bromberg, J. F., Fan, Z., Brown, C., Mendelsohn, J., Darnell, J. E. Jr. (1998) Epidermal growth factor-induced growth inhibition requires Stat1 activation. Cell Growth Differ. 9, 505-512.
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 505-512
-
-
Bromberg, J.F.1
Fan, Z.2
Brown, C.3
Mendelsohn, J.4
Darnell Jr., J.E.5
-
12
-
-
0036554816
-
Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
-
Buettner, R., Mora, L. B., Jove, R. (2002) Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin. Cancer Res. 8, 945-954.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 945-954
-
-
Buettner, R.1
Mora, L.B.2
Jove, R.3
-
13
-
-
0034616170
-
Interleukin-4 mediates cell growth inhibition through activation of Stat1
-
Chang, T. L., Peng, X., Fu, X. Y. (2000) Interleukin-4 mediates cell growth inhibition through activation of Stat1. J. Biol. Chem. 275, 10212-10217.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10212-10217
-
-
Chang, T.L.1
Peng, X.2
Fu, X.Y.3
-
14
-
-
0034254726
-
How Stat1 mediates constitutive gene expression: A complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene
-
Chattedee-Kishore, M., Wright, K. L., Ting, J. P., Stark, G. R. (2000). How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene. EMBO J. 19, 4111-4122.
-
(2000)
EMBO J.
, vol.19
, pp. 4111-4122
-
-
Chattedee-Kishore, M.1
Wright, K.L.2
Ting, J.P.3
Stark, G.R.4
-
15
-
-
0029923780
-
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WNF1/CIP1 mediated by STAT1
-
Chin, Y. E., Kitagawa, M., Su, W. C., You, Z. H., Iwamoto, Y., Fu, X. Y. (1996) Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WNF1/CIP1 mediated by STAT1. Science 272, 719-722.
-
(1996)
Science
, vol.272
, pp. 719-722
-
-
Chin, Y.E.1
Kitagawa, M.2
Su, W.C.3
You, Z.H.4
Iwamoto, Y.5
Fu, X.Y.6
-
16
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell, J. E. Jr., Kerr, I. M., Stark, Q. R. (1994) Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415-1421.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell Jr., J.E.1
Kerr, I.M.2
Stark, Q.R.3
-
17
-
-
2642588293
-
Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: Exacerbation of joint inflammation in STAT-1 gene-knockout mice
-
de Hooge, A. S., van de Loo, F. A., Koenders, M. L., Bennink, M. B., Arntz, O. J., Kolbe, T., van den Berg, W. B. (2004) Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice. Arthritis Rheum. 50, 2014-2023.
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 2014-2023
-
-
de Hooge, A.S.1
van de Loo, F.A.2
Koenders, M.L.3
Bennink, M.B.4
Arntz, O.J.5
Kolbe, T.6
van den Berg, W.B.7
-
18
-
-
0030024563
-
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
-
Durbin, J. E., Hackenmiller, R., Simon, M. C., Levy, D. E. (1996) Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. Cell 84, 443-450.
-
(1996)
Cell
, vol.84
, pp. 443-450
-
-
Durbin, J.E.1
Hackenmiller, R.2
Simon, M.C.3
Levy, D.E.4
-
19
-
-
0034655279
-
Type I IFN modulates innate and specific antiviral immunity
-
Durbin, J. E., Fernandez-Sesma, A., Lee, C. K., Rao, T. D., Frey, A. B., Moran, T. M., Vukmanovic, S., Garcia-Sastre, A., Levy, D. E. (2000) Type I IFN modulates innate and specific antiviral immunity. J. Immunol. 164, 4220-4228.
-
(2000)
J. Immunol.
, vol.164
, pp. 4220-4228
-
-
Durbin, J.E.1
Fernandez-Sesma, A.2
Lee, C.K.3
Rao, T.D.4
Frey, A.B.5
Moran, T.M.6
Vukmanovic, S.7
Garcia-Sastre, A.8
Levy, D.E.9
-
20
-
-
29144475515
-
Global changes in STAT target selection and transcription regulation upon interferon treatments
-
Hartman, S. E., Bertone, P., Nath, A. K., Royce, T. E., Gerstein, M., Weissman, S., Snyder, M. (2005) Global changes in STAT target selection and transcription regulation upon interferon treatments. Genes Dev. 19, 2953-2968.
-
(2005)
Genes Dev.
, vol.19
, pp. 2953-2968
-
-
Hartman, S.E.1
Bertone, P.2
Nath, A.K.3
Royce, T.E.4
Gerstein, M.5
Weissman, S.6
Snyder, M.7
-
21
-
-
0034057086
-
Thrombin inhibits tumor cell growth in association with up-regulation of p21 (waf/cipl) and caspases via a p53-independent, STAT1-dependent pathway
-
Huang, Y. Q., Li, J. J., Karpatkin, S. (2000) Thrombin inhibits tumor cell growth in association with up-regulation of p21 (waf/cipl) and caspases via a p53-independent, STAT1-dependent pathway J. Biol. Chem. 275, 6462-6468.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6462-6468
-
-
Huang, Y.Q.1
Li, J.J.2
Karpatkin, S.3
-
22
-
-
0028921573
-
Jaks, and Stats in signaling by the cytokine receptor superfamily
-
Ihle, J. N., Kerr, I. M. (1995) Jaks, and Stats in signaling by the cytokine receptor superfamily. Trends Genet. 11, 69-74.
-
(1995)
Trends Genet.
, vol.11
, pp. 69-74
-
-
Ihle, J.N.1
Kerr, I.M.2
-
23
-
-
0036005884
-
The roles of IFN γ in protection against tumor development and cancer immunoediting
-
Ikeda, H., Old, L. J., Schreiber, R. D. (2002) The roles of IFN γ in protection against tumor development and cancer immunoediting. Cytokine Growth Factor Rev. 13, 95-109.
-
(2002)
Cytokine Growth Factor Rev.
, vol.13
, pp. 95-109
-
-
Ikeda, H.1
Old, L.J.2
Schreiber, R.D.3
-
25
-
-
0036790295
-
The C-terminal activation domain of the STAT-1 transcription factor is necessary and sufficient for stress-induced apoptosis
-
Janjua, S., Stephanou, A., Latchman, D. S. (2002) The C-terminal activation domain of the STAT-1 transcription factor is necessary and sufficient for stress-induced apoptosis. Cell Death Differ. 9, 1140-1146.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 1140-1146
-
-
Janjua, S.1
Stephanou, A.2
Latchman, D.S.3
-
26
-
-
0032560475
-
Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice
-
Kaplan, D. H., Shankaran, V., Dighe, A. S., Stockert, E., Aguet, M., Old, L. J., Schreiber, R. D. (1998) Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice. Proc. Natl. Acad. Sci. USA 95, 7556-7561.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7556-7561
-
-
Kaplan, D.H.1
Shankaran, V.2
Dighe, A.S.3
Stockert, E.4
Aguet, M.5
Old, L.J.6
Schreiber, R.D.7
-
27
-
-
15444353992
-
Apoptosis of colorectal adenocarcinoma (COLO 201) by tumour necrosis factor-α (TNF-α) and/or interferon-γ (IFN-γ), resulting from down-modulation of Bcl-2 expression
-
Koshiji, M., Adachi, Y., Sogo, S., Taketani, S., Oyaizu, N., Than, S., Inaba, M., Phawa, S., Hioki, K., Ikehara, S. (1998) Apoptosis of colorectal adenocarcinoma (COLO 201) by tumour necrosis factor-α (TNF-α) and/or interferon-γ (IFN-γ), resulting from down-modulation of Bcl-2 expression. Clin. Exp. Immunol. 111, 211-218.
-
(1998)
Clin. Exp. Immunol.
, vol.111
, pp. 211-218
-
-
Koshiji, M.1
Adachi, Y.2
Sogo, S.3
Taketani, S.4
Oyaizu, N.5
Than, S.6
Inaba, M.7
Phawa, S.8
Hioki, K.9
Ikehara, S.10
-
28
-
-
33646973354
-
Interferon γ but not α induce SOCS 3 expression of human melanoma cell lines
-
Kovarik, A., Fojtova, M., Boudny, V., Adamkova, L., Lauerova, L., Kovarik, J. (2005) Interferon γ but not α induce SOCS 3 expression of human melanoma cell lines. Melanoma Res. 15, 481-488.
-
(2005)
Melanoma Res.
, vol.15
, pp. 481-488
-
-
Kovarik, A.1
Fojtova, M.2
Boudny, V.3
Adamkova, L.4
Lauerova, L.5
Kovarik, J.6
-
29
-
-
0642364433
-
Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation
-
Kovarik, J., Boudny, V., Kocak, I., Lauerova, L., Fait, V, Vagundova, M. (2003) Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. Int. J. Mol. Med. 12, 335-340.
-
(2003)
Int. J. Mol. Med.
, vol.12
, pp. 335-340
-
-
Kovarik, J.1
Boudny, V.2
Kocak, I.3
Lauerova, L.4
Fait, V.5
Vagundova, M.6
-
30
-
-
0035862950
-
Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression
-
Kovarik, P., Mangold, M., Ramsauer, K., Heidari, H., Steinborn, R., Zotter, A., Levy, D. E., Muller, M., Decker, T. (2001) Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression. EMBO J. 20, 91-100.
-
(2001)
EMBO J.
, vol.20
, pp. 91-100
-
-
Kovarik, P.1
Mangold, M.2
Ramsauer, K.3
Heidari, H.4
Steinborn, R.5
Zotter, A.6
Levy, D.E.7
Muller, M.8
Decker, T.9
-
31
-
-
0030659512
-
Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases
-
Kumar, A., Commane, M., Flickinger, T. W., Horvath, C. M., Stark, G. R. (1997) Defective TNF-α-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases. Science 278, 1630-1632.
-
(1997)
Science
, vol.278
, pp. 1630-1632
-
-
Kumar, A.1
Commane, M.2
Flickinger, T.W.3
Horvath, C.M.4
Stark, G.R.5
-
32
-
-
0034292328
-
Distinct requirements for IFNs and STAT1 in NK cell function
-
Lee, C. K., Rao, D. T., Gertner, R., Gimeno, R., Frey, A. B., Levy, D. E. (2000a) Distinct requirements for IFNs and STAT1 in NK cell function. J. Immunol. 165, 3571-3577.
-
(2000)
J. Immunol.
, vol.165
, pp. 3571-3577
-
-
Lee, C.K.1
Rao, D.T.2
Gertner, R.3
Gimeno, R.4
Frey, A.B.5
Levy, D.E.6
-
33
-
-
0034142230
-
STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-γ
-
Lee, C. K., Smith, E., Gimeno, R., Gertner, R., Levy, D. E. (2000b) STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-γ. J. Immunol. 164, 1286-1292.
-
(2000)
J. Immunol.
, vol.164
, pp. 1286-1292
-
-
Lee, C.K.1
Smith, E.2
Gimeno, R.3
Gertner, R.4
Levy, D.E.5
-
34
-
-
0000146587
-
Differential regulation and function of Fas expression on glial cells
-
Lee, S. J., Zhou, T., Choi, C., Wang, Z., Benveniste, E. N. (2000c) Differential regulation and function of Fas expression on glial cells. J. Immunol. 164, 1277-1285.
-
(2000)
J. Immunol.
, vol.164
, pp. 1277-1285
-
-
Lee, S.J.1
Zhou, T.2
Choi, C.3
Wang, Z.4
Benveniste, E.N.5
-
35
-
-
0034658690
-
Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice
-
Levy, D. E., Gilliland, D. G. (2000) Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice. Oncogene 19, 2505-2510.
-
(2000)
Oncogene
, vol.19
, pp. 2505-2510
-
-
Levy, D.E.1
Gilliland, D.G.2
-
36
-
-
0142027777
-
Distribution of NF-κB-binding sites across human chromosome 22
-
Martone, R., Euskirchen, G., Bertone, P., Hartman, S., Royce, T. E., Luscombe, N. M., Rinn, J. L., Nelson, F. K., Miller, P., Gerstein, M., Weissman, S., Snyder, M. (2003) Distribution of NF-κB-binding sites across human chromosome 22. Proc. Natl. Acad. Sci. USA 100, 12247-12252.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12247-12252
-
-
Martone, R.1
Euskirchen, G.2
Bertone, P.3
Hartman, S.4
Royce, T.E.5
Luscombe, N.M.6
Rinn, J.L.7
Nelson, F.K.8
Miller, P.9
Gerstein, M.10
Weissman, S.11
Snyder, M.12
-
37
-
-
0035902571
-
JAK/STAT signaling is associated with cardiac dysfunction during ischemia and reperfusion
-
Mascareno, E., El-Shafei, M., Maulik, N., Sato, M., Guo, Y., Das, D. K., Siddiqui, M. A. (2001) JAK/STAT signaling is associated with cardiac dysfunction during ischemia and reperfusion. Circulation 104, 325-329.
-
(2001)
Circulation
, vol.104
, pp. 325-329
-
-
Mascareno, E.1
El-Shafei, M.2
Maulik, N.3
Sato, M.4
Guo, Y.5
Das, D.K.6
Siddiqui, M.A.7
-
38
-
-
13344282731
-
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
-
Meraz, M. A., White, J. M., Sheehan, K. C., Bach, E. A., Rodig, S. J., Dighe, A. S., Kaplan, D. H., Riley, J. K., Greenlund, A. C., Campbell, D., Carver-Moore, K., DuBois, R. N., Clark, R., Aguet, M., Schreiber, R. D. (1996) Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84, 431-442.
-
(1996)
Cell
, vol.84
, pp. 431-442
-
-
Meraz, M.A.1
White, J.M.2
Sheehan, K.C.3
Bach, E.A.4
Rodig, S.J.5
Dighe, A.S.6
Kaplan, D.H.7
Riley, J.K.8
Greenlund, A.C.9
Campbell, D.10
Carver-Moore, K.11
DuBois, R.N.12
Clark, R.13
Aguet, M.14
Schreiber, R.D.15
-
39
-
-
0027434082
-
Complementation of a mutant cell line: Central role of the 91 kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathways
-
Muller, M., Laxton, C., Briscoe, J., Schindler, C., Improta, T., Darnell, J. E. Jr, Stark, G. R., Kerr, I. M. (1993) Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathways. EMBO J. 12, 4221-4228.
-
(1993)
EMBO J.
, vol.12
, pp. 4221-4228
-
-
Muller, M.1
Laxton, C.2
Briscoe, J.3
Schindler, C.4
Improta, T.5
Darnell Jr., J.E.6
Stark, G.R.7
Kerr, I.M.8
-
40
-
-
0033213901
-
Negative regulation of cytokine signaling: STAT-induced STAT inhibitor
-
Naka, T., Fujimoto, M., Kishimoto, T. (1999) Negative regulation of cytokine signaling: STAT-induced STAT inhibitor. Trends Biochem. Sci. 24, 394-398.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 394-398
-
-
Naka, T.1
Fujimoto, M.2
Kishimoto, T.3
-
41
-
-
0346024088
-
Impaired development of CD4+ CD25+ regulatory T cells in the absence of STAT1: Increased susceptibility to autoimmune disease
-
Nishibori, T., Tanabe, Y., Su, L., David, M. (2004) Impaired development of CD4+ CD25+ regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease. J. Exp. Med. 199, 25-34.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 25-34
-
-
Nishibori, T.1
Tanabe, Y.2
Su, L.3
David, M.4
-
42
-
-
0030985893
-
Interferon-γ modulates a p53-independent apoptotic pathway and apoptosis-related gene expression
-
Ossina, N. K., Cannas, A., Powers, V. C., Fitzpatrick, P. A., Knight, J. D., Gilbert, J. R., Shekhtman, E. M., Tomei, L. D., Umansky, S. R., Kiefer, M. C. (1997) Interferon-γ modulates a p53-independent apoptotic pathway and apoptosis-related gene expression. J. Biol. Chem. 272, 16351-16357.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16351-16357
-
-
Ossina, N.K.1
Cannas, A.2
Powers, V.C.3
Fitzpatrick, P.A.4
Knight, J.D.5
Gilbert, J.R.6
Shekhtman, E.M.7
Tomei, L.D.8
Umansky, S.R.9
Kiefer, M.C.10
-
43
-
-
0033973215
-
Defective Jak-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-α
-
Pansky, A., Hildebrand, P., Fasler-Kan, E., Baselgia, L., Ketterer, S., Beglinger, C., Heim, M. H. (2000) Defective Jak-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-α. Int. J. Cancer 85, 720-725.
-
(2000)
Int. J. Cancer
, vol.85
, pp. 720-725
-
-
Pansky, A.1
Hildebrand, P.2
Fasler-Kan, E.3
Baselgia, L.4
Ketterer, S.5
Beglinger, C.6
Heim, M.H.7
-
44
-
-
0034658696
-
Complex roles of Stat1 in regulating gene expression
-
Ramana, C. V., Chatterjee-Kishore, M., Nguyen, H., Stark, G. R. (2000) Complex roles of Stat1 in regulating gene expression. Oncogene 19, 2619-2627.
-
(2000)
Oncogene
, vol.19
, pp. 2619-2627
-
-
Ramana, C.V.1
Chatterjee-Kishore, M.2
Nguyen, H.3
Stark, G.R.4
-
45
-
-
0034960254
-
STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2
-
Sahni, M., Raz, R., Coffin, J. D., Levy, D., Basilico, C. (2001) STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2. Development 128, 2119-2129.
-
(2001)
Development
, vol.128
, pp. 2119-2129
-
-
Sahni, M.1
Raz, R.2
Coffin, J.D.3
Levy, D.4
Basilico, C.5
-
46
-
-
0026725868
-
Proteins of transcription factor ISGF-3: One gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon α
-
Schindler, C., Fu, X. Y., Improta, T., Aebersold, R., Darnell, J. E. Jr. (1992) Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon α. Proc. Natl. Acad. Sci. USA 89, 7836-7839.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7836-7839
-
-
Schindler, C.1
Fu, X.Y.2
Improta, T.3
Aebersold, R.4
Darnell Jr., J.E.5
-
47
-
-
0028937707
-
Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity
-
Seidel, H. M., Milocco, L. H., Lamb, P., Darnell, J. E. Jr., Stein, R. B., Rosen, J. (1995) Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity. Proc. Natl. Acad. Sci. USA 92, 3041-3045.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3041-3045
-
-
Seidel, H.M.1
Milocco, L.H.2
Lamb, P.3
Darnell Jr., J.E.4
Stein, R.B.5
Rosen, J.6
-
48
-
-
0035953308
-
IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
-
Shankaran, V., Ikeda, H., Bruce, A. T., White, J. M., Swanson, P. E., Old, L. J., Schreiber, R. D. (2001) IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 410, 1107-1111.
-
(2001)
Nature
, vol.410
, pp. 1107-1111
-
-
Shankaran, V.1
Ikeda, H.2
Bruce, A.T.3
White, J.M.4
Swanson, P.E.5
Old, L.J.6
Schreiber, R.D.7
-
49
-
-
0035879751
-
IFN-γ induces cell death in human hepatoma cells through a TRAIL/death receptor-mediated apoptotic pathway
-
Shin, E. C., Ahn, J. M., Kim, C. H., Choi, Y., Alin, Y. S., Kim, H., Kim, S. J., Park, J. H. (2001) IFN-γ induces cell death in human hepatoma cells through a TRAIL/death receptor-mediated apoptotic pathway. Int. J. Cancer 93, 262-268.
-
(2001)
Int. J. Cancer
, vol.93
, pp. 262-268
-
-
Shin, E.C.1
Ahn, J.M.2
Kim, C.H.3
Choi, Y.4
Alin, Y.S.5
Kim, H.6
Kim, S.J.7
Park, J.H.8
-
50
-
-
0032921172
-
The STAT family of proteins in cytokine signaling
-
Shuai, K. (1999) The STAT family of proteins in cytokine signaling. Prog. Biophys. Mol. Biol. 71, 405-422.
-
(1999)
Prog. Biophys. Mol. Biol.
, vol.71
, pp. 405-422
-
-
Shuai, K.1
-
51
-
-
0034657917
-
Modulation of STAT signaling by STAT-interacting proteins
-
Shuai, K. (2000) Modulation of STAT signaling by STAT-interacting proteins. Oncogene 19, 2638-2644.
-
(2000)
Oncogene
, vol.19
, pp. 2638-2644
-
-
Shuai, K.1
-
52
-
-
0027772891
-
Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins
-
Shuai, K., Ziemiecki, A., Wilks, A. F., Harpur, A. G., Sadowski, H. B., Gilman, M. Z., Darnell, J. E. (1993) Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins. Nature 366, 580-583.
-
(1993)
Nature
, vol.366
, pp. 580-583
-
-
Shuai, K.1
Ziemiecki, A.2
Wilks, A.F.3
Harpur, A.G.4
Sadowski, H.B.5
Gilman, M.Z.6
Darnell, J.E.7
-
53
-
-
0031657551
-
How cells respond to interferons
-
Stark, G. R., Kerr, I. M., Williams, B. R., Silverman, R. H., Schreiber, R. D. (1998) How cells respond to interferons. Annu. Rev. Biochem. 67, 227-264.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.3
Silverman, R.H.4
Schreiber, R.D.5
-
54
-
-
0032966863
-
Negative regulation of the JAK/STAT pathway
-
Starr, R., Hilton, D. J. (1999) Negative regulation of the JAK/STAT pathway. BioEssays 21, 47-52.
-
(1999)
BioEssays
, vol.21
, pp. 47-52
-
-
Starr, R.1
Hilton, D.J.2
-
55
-
-
0034616164
-
Ischemia-induced STAT-1 expression and activation play a critical role in cardiomyocyte apoptosis
-
Stephanou, A., Brar, B. K., Scarabelli, T. M., Jonassen, A. K., Yellon, D. M., Marber, M. S., Knight, R. A., Latchman, D. S. (2000) Ischemia-induced STAT-1 expression and activation play a critical role in cardiomyocyte apoptosis. J. Biol. Chem. 275, 10002-10008.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10002-10008
-
-
Stephanou, A.1
Brar, B.K.2
Scarabelli, T.M.3
Jonassen, A.K.4
Yellon, D.M.5
Marber, M.S.6
Knight, R.A.7
Latchman, D.S.8
-
56
-
-
32144463144
-
Opposing actions of STAT-1 and STAT-3
-
Stephanou, A., Latchman, D. S. (2005) Opposing actions of STAT-1 and STAT-3. Growth Factors 23, 177-182.
-
(2005)
Growth Factors
, vol.23
, pp. 177-182
-
-
Stephanou, A.1
Latchman, D.S.2
-
57
-
-
0030896404
-
Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism
-
Su, W. C., Kitagawa, M., Xue, N., Xie, B., Garofalo, S., Cho, J., Deng, C., Horton, W. A., Fu, X. Y. (1997) Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism. Nature 386, 288-292.
-
(1997)
Nature
, vol.386
, pp. 288-292
-
-
Su, W.C.1
Kitagawa, M.2
Xue, N.3
Xie, B.4
Garofalo, S.5
Cho, J.6
Deng, C.7
Horton, W.A.8
Fu, X.Y.9
-
58
-
-
0035313059
-
IFN-γ/TNF-α synergism as the final effector in autoimmune diabetes: A key role for STAT1/IFN regulatory factor-1 pathway in pancreatic β cell death
-
Suk, K., Kim, S., Kim, Y H., Kim, K. A., Chang, I., Yagita, H., Shong, M., Lee, M. S. (2001) IFN-γ/TNF-α synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic β cell death. J. Immunol. 166, 4481-4489.
-
(2001)
J. Immunol.
, vol.166
, pp. 4481-4489
-
-
Suk, K.1
Kim, S.2
Kim, Y.H.3
Kim, K.A.4
Chang, I.5
Yagita, H.6
Shong, M.7
Lee, M.S.8
-
59
-
-
0037129205
-
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β
-
Takayanagi, H., Kim, S., Matsuo, K., Suzuki, H., Suzuki, T., Sato, K., Yokochi, T., Oda, H., Nakamura, K., Ida, N., Wagner, E. F., Taniguchi, T. (2002) RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β. Nature 416, 744-749.
-
(2002)
Nature
, vol.416
, pp. 744-749
-
-
Takayanagi, H.1
Kim, S.2
Matsuo, K.3
Suzuki, H.4
Suzuki, T.5
Sato, K.6
Yokochi, T.7
Oda, H.8
Nakamura, K.9
Ida, N.10
Wagner, E.F.11
Taniguchi, T.12
-
60
-
-
0034046605
-
STAT family of transcription factors in cytokine-mediated biological responses
-
Takeda, K., Akira, S. (2000) STAT family of transcription factors in cytokine-mediated biological responses. Cytokine Growth Factor Rev. 11, 199-207.
-
(2000)
Cytokine Growth Factor Rev.
, vol.11
, pp. 199-207
-
-
Takeda, K.1
Akira, S.2
-
61
-
-
0036318564
-
Identification of a nuclear Stat1 protein tyrosine phosphatase
-
ten Hoeve, J., de Jesus Ibarra-Sanchez, M., Fu, Y., Zhu, W., Tremblay, M., David, M., Shuai, K. (2002) Identification of a nuclear Stat1 protein tyrosine phosphatase. Mol. Cell. Biol. 22, 5662-5668.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5662-5668
-
-
ten Hoeve, J.1
de Jesus Ibarra-Sanchez, M.2
Fu, Y.3
Zhu, W.4
Tremblay, M.5
David, M.6
Shuai, K.7
-
62
-
-
8544281698
-
STAT1: A modulator of chemotherapy-induced apoptosis
-
Thomas, M., Finnegan, C. E., Rogers, K. M., Purcell, J. W., Trimble, A., Johnston, P. G, Boland, M. P. (2004) STAT1: a modulator of chemotherapy-induced apoptosis. Cancer Res. 64, 8357-8364.
-
(2004)
Cancer Res.
, vol.64
, pp. 8357-8364
-
-
Thomas, M.1
Finnegan, C.E.2
Rogers, K.M.3
Purcell, J.W.4
Trimble, A.5
Johnston, P.G.6
Boland, M.P.7
-
63
-
-
33845539491
-
Serine-phosphorylated STAT1 is a prosurvival factor in Wilms' tumor pathogenesis
-
doi:10.1038/sj.onc.1209742
-
Timofeeva, O. A., Plisov, S., Evseev, A. A., Peng, S., Jose-Kampfner, M., Lovvorn, H. N., Dome, J. S., Perantoni, A. O. (2006) Serine-phosphorylated STAT1 is a prosurvival factor in Wilms' tumor pathogenesis. Oncogene 25, doi:10.1038/sj.onc.1209742.
-
(2006)
Oncogene
, vol.25
-
-
Timofeeva, O.A.1
Plisov, S.2
Evseev, A.A.3
Peng, S.4
Jose-Kampfner, M.5
Lovvorn, H.N.6
Dome, J.S.7
Perantoni, A.O.8
-
64
-
-
1242316989
-
STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis
-
Townsend, P. A., Scarabelli, T. M., Davidson, S. M., Knight, R. A., Latchman, D. S., Stephanou, A. (2004) STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis. J. Biol. Chem. 279, 5811-5820.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5811-5820
-
-
Townsend, P.A.1
Scarabelli, T.M.2
Davidson, S.M.3
Knight, R.A.4
Latchman, D.S.5
Stephanou, A.6
-
65
-
-
0036793979
-
Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer
-
Widschwendter, A., Tonko-Geymayer, S., Welte, T., Daxenbichler, G., Marth, C., Doppler, W. (2002) Prognostic significance of signal transducer and activator of transcription 1 activation in breast cancer. Clin. Cancer Res. 8, 3065-3074.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3065-3074
-
-
Widschwendter, A.1
Tonko-Geymayer, S.2
Welte, T.3
Daxenbichler, G.4
Marth, C.5
Doppler, W.6
-
66
-
-
0030712998
-
Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma
-
Wong, L. H., Krauer, K. G., Hatzinisiriou, I., Estcourt, M. J., Hersey, P., Tam, N. D., Edmondson, S., Devenish, R. J., Ralph, S. J. (1997) Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma. J. Biol. Chem. 272, 28779-28785.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28779-28785
-
-
Wong, L.H.1
Krauer, K.G.2
Hatzinisiriou, I.3
Estcourt, M.J.4
Hersey, P.5
Tam, N.D.6
Edmondson, S.7
Devenish, R.J.8
Ralph, S.J.9
-
67
-
-
33750577456
-
Proximal genomic localization of STAT1 binding and regulated transcriptional activity
-
Wormald, S., Hilton, D. J., Smyth, G. K., Speed, T. P. (2006a) Proximal genomic localization of STAT1 binding and regulated transcriptional activity. BMC Genomics 7, 254.
-
(2006)
BMC Genomics
, vol.7
, pp. 254
-
-
Wormald, S.1
Hilton, D.J.2
Smyth, G.K.3
Speed, T.P.4
-
68
-
-
33744963148
-
The comparative roles of suppressor of cytokine signaling-1 and -3 in the inhibition and desensitization of cytokine signaling
-
Wormald, S., Zhang, J. G., Krebs, D. L., Mielke, L. A., Silver, J., Alexander, W. S., Speed, T. P., Nicola, N. A., Hilton, D. J. (2006b) The comparative roles of suppressor of cytokine signaling-1 and -3 in the inhibition and desensitization of cytokine signaling. J. Biol. Chem. 281, 11135-11143.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 11135-11143
-
-
Wormald, S.1
Zhang, J.G.2
Krebs, D.L.3
Mielke, L.A.4
Silver, J.5
Alexander, W.S.6
Speed, T.P.7
Nicola, N.A.8
Hilton, D.J.9
-
69
-
-
0032528191
-
Expression of signal transducers and activators of transcription proteins in acute myeloid leukemia blasts
-
Xia, Z., Baer, M. R., Block, A. W., Baumann, H., Wetzler, M. (1998) Expression of signal transducers and activators of transcription proteins in acute myeloid leukemia blasts. Cancer Res. 58, 3173-3180.
-
(1998)
Cancer Res.
, vol.58
, pp. 3173-3180
-
-
Xia, Z.1
Baer, M.R.2
Block, A.W.3
Baumann, H.4
Wetzler, M.5
-
70
-
-
0032125574
-
IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: Requirement of STAT1 protein for up-regulation of Fas and FasL expression
-
Xu, X., Fu, X. Y, Plate, J., Chong, A. S. (1998) IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression. Cancer Res. 58, 2832-2837.
-
(1998)
Cancer Res.
, vol.58
, pp. 2832-2837
-
-
Xu, X.1
Fu, X.Y.2
Plate, J.3
Chong, A.S.4
-
71
-
-
0032980574
-
Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway
-
You, M., Yu, D. H., Feng, G. S. (1999) Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway. Mol. Cell. Biol. 19, 2416-2424.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2416-2424
-
-
You, M.1
Yu, D.H.2
Feng, G.S.3
|