Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathway

Journal of Biological Chemistry

Volumn 275, Issue 9, 2000, Pages 6462-6468

  Huang, Yao Qi ^a   Li, Jian Jun ^a   Karpatkin, Simon ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; ISOENZYME; PROTEIN P21; PROTEIN P53; PROTEINASE ACTIVATED RECEPTOR 1; STAT1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; THROMBIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; RECEPTOR BINDING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; CASPASES; CELL DIVISION; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA; DNA-BINDING PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MEGAKARYOCYTES; MICE; PHOSPHORYLATION; RECEPTOR, PAR-1; RECEPTORS, THROMBIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; THROMBIN; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED; UP-REGULATION;

ANIMALIA; MURINAE; RICKETTSIA SP. PAR;

EID: 0034057086     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.9.6462     Document Type: Article

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