-
1
-
-
0030840464
-
STATs and gene regulation
-
Darnell JE Jr. STATs and gene regulation [review]. Science 1997; 277:1630-1635.
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell Jr., J.E.1
-
2
-
-
0344440953
-
Regulation of cytokine signaling by SOCS family molecules
-
Fujimoto M, Naka T. Regulation of cytokine signaling by SOCS family molecules. Trends Immunol 2003; 24:659-666.
-
(2003)
Trends Immunol
, vol.24
, pp. 659-666
-
-
Fujimoto, M.1
Naka, T.2
-
3
-
-
0034841006
-
Negative regulation of cytokine signaling
-
Greenhalgh CJ, Hilton DJ. Negative regulation of cytokine signaling. J Leuk Biol 2001; 70:348-356.
-
(2001)
J Leuk Biol
, vol.70
, pp. 348-356
-
-
Greenhalgh, C.J.1
Hilton, D.J.2
-
4
-
-
0029069145
-
Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
-
Schindler C, Darnell JE Jr. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway [review]. Annu Rev Biochem 1995; 64:621-651.
-
(1995)
Annu Rev Biochem
, vol.64
, pp. 621-651
-
-
Schindler, C.1
Darnell Jr., J.E.2
-
5
-
-
0032772912
-
STAT signaling in the pathogenesis and treatment of cancer
-
Frank DA. STAT signaling in the pathogenesis and treatment of cancer [review]. Mol Med 1999; 5:432-456.
-
(1999)
Mol Med
, vol.5
, pp. 432-456
-
-
Frank, D.A.1
-
6
-
-
0036233585
-
Cytokine signaling in 2002: New surprises in the JAK/STAT pathway
-
O'Shea JJ, Gadina M, Schreiber RD. Cytokine signaling in 2002: new surprises in the JAK/STAT pathway [review]. Cell 2002; 109 (Suppl):S121-S131.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
-
-
O'Shea, J.J.1
Gadina, M.2
Schreiber, R.D.3
-
7
-
-
0034658024
-
Serine phosphorylation of STATs
-
Decker T, Kovarik P. Serine phosphorylation of STATs. Oncogene 2000; 19:2628-2637.
-
(2000)
Oncogene
, vol.19
, pp. 2628-2637
-
-
Decker, T.1
Kovarik, P.2
-
8
-
-
0035862950
-
Specificity of signaling by STAT 1 depends on SH2 and C-terminal domains that regulate Ser 727 phosphorylation, differentially affecting specific target gene expression
-
Kovarik P, Mangold M, Ramsauer K, Heidari H, Steinborn R, Zotter A, et al. Specificity of signaling by STAT 1 depends on SH2 and C-terminal domains that regulate Ser 727 phosphorylation, differentially affecting specific target gene expression. EMBO J 2001; 20:91-100.
-
(2001)
EMBO J
, vol.20
, pp. 91-100
-
-
Kovarik, P.1
Mangold, M.2
Ramsauer, K.3
Heidari, H.4
Steinborn, R.5
Zotter, A.6
-
9
-
-
1642463842
-
The roles of JAK/STAT signaling in Drosophila immune responses
-
Agaisse H, Perrimon N. The roles of JAK/STAT signaling in Drosophila immune responses. Immunol Rev 2004; 198:72-82.
-
(2004)
Immunol Rev
, vol.198
, pp. 72-82
-
-
Agaisse, H.1
Perrimon, N.2
-
10
-
-
11144357779
-
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
-
Wang T, Niu G, Kortylewski M, Burdelya L, Shain K, Zhang S, et al. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nat Med 2004; 10:48-54.
-
(2004)
Nat Med
, vol.10
, pp. 48-54
-
-
Wang, T.1
Niu, G.2
Kortylewski, M.3
Burdelya, L.4
Shain, K.5
Zhang, S.6
-
11
-
-
19944387916
-
IL-2 overcomes the unresponsiveness but fails to reverse the regulatory function of antigen-induced T regulatory cells
-
Anderson PO, Sundstedt A, Yazici Z, Minaee S, Woolf R, Nicolson K, et al. IL-2 overcomes the unresponsiveness but fails to reverse the regulatory function of antigen-induced T regulatory cells. J Immunol 2005; 174:310-319.
-
(2005)
J Immunol
, vol.174
, pp. 310-319
-
-
Anderson, P.O.1
Sundstedt, A.2
Yazici, Z.3
Minaee, S.4
Woolf, R.5
Nicolson, K.6
-
12
-
-
0036480027
-
Suppressors of cytokine signalling (SOCS): Inhibitors of the JAK/STAT pathway
-
Cooney RN. Suppressors of cytokine signalling (SOCS): inhibitors of the JAK/STAT pathway. Shock 2002; 17:83-90.
-
(2002)
Shock
, vol.17
, pp. 83-90
-
-
Cooney, R.N.1
-
13
-
-
0242285719
-
STAT proteins: From normal control of cellular events to tumorigenesis
-
Calo V, Migliavacca M, Bazan V, Macaluso M, Buscemi M, Gebbia N, Russo A. STAT proteins: from normal control of cellular events to tumorigenesis. J Cell Physiol 2003; 197:157-168.
-
(2003)
J Cell Physiol
, vol.197
, pp. 157-168
-
-
Calo, V.1
Migliavacca, M.2
Bazan, V.3
Macaluso, M.4
Buscemi, M.5
Gebbia, N.6
Russo, A.7
-
14
-
-
0345492424
-
SOCS 3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer
-
He B, You L, Uematsu K, Zang K, Xu Z, Lee AY, et al. SOCS 3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer. Proc Natl Acad Sci USA 2003; 100:14 133-14 138.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14133-14138
-
-
He, B.1
You, L.2
Uematsu, K.3
Zang, K.4
Xu, Z.5
Lee, A.Y.6
-
15
-
-
0035006109
-
Tyrosine-phosphorylated SOCS 3 inhibits STAT activation but binds to p120 RasGAP and activates Ras
-
Cacalano NA, Sanden D, Johnston JA. Tyrosine-phosphorylated SOCS 3 inhibits STAT activation but binds to p120 RasGAP and activates Ras. Nat Cell Biol 2001; 3:460-465.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 460-465
-
-
Cacalano, N.A.1
Sanden, D.2
Johnston, J.A.3
-
16
-
-
0033973215
-
Defective JAK-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-alpha
-
Pansky A, Hildebrand P, Fasler-Kan E, Baselgia L, Ketterer S, Beglinger C, Heim MH. Defective JAK-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-alpha. Int J Cancer 2000; 85:720-725.
-
(2000)
Int J Cancer
, vol.85
, pp. 720-725
-
-
Pansky, A.1
Hildebrand, P.2
Fasler-Kan, E.3
Baselgia, L.4
Ketterer, S.5
Beglinger, C.6
Heim, M.H.7
-
17
-
-
22244457944
-
Expression of STAT 1 and STAT 2 in malignant melanoma does not correlate with response to interferon-alpha adjuvant therapy
-
Lesinski GB, Valentino D, Hade EM, Jones S, Chaudhury AR, Walker MJ, Carson WE 3rd. Expression of STAT 1 and STAT 2 in malignant melanoma does not correlate with response to interferon-alpha adjuvant therapy. Cancer Immunol Immunother 2005; 54:815-825.
-
(2005)
Cancer Immunol Immunother
, vol.54
, pp. 815-825
-
-
Lesinski, G.B.1
Valentino, D.2
Hade, E.M.3
Jones, S.4
Chaudhury, A.R.5
Walker, M.J.6
Carson III, W.E.7
-
18
-
-
0022393181
-
Characteristics of cultured human melanocytes isolated from different stages of tumor progression
-
Herlyn M, Thurin J, Balaban G, Bennicelli JL, Herlyn D, Elder DE, et al. Characteristics of cultured human melanocytes isolated from different stages of tumor progression. Cancer Res 1985; 45:5670-5676.
-
(1985)
Cancer Res
, vol.45
, pp. 5670-5676
-
-
Herlyn, M.1
Thurin, J.2
Balaban, G.3
Bennicelli, J.L.4
Herlyn, D.5
Elder, D.E.6
-
19
-
-
0642364433
-
Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation
-
Kovarik J, Boudny V, Kocak I, Lauerova L, Fait V, Vagundova M. Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. Int J Mol Med 2003; 12:335-340.
-
(2003)
Int J Mol Med
, vol.12
, pp. 335-340
-
-
Kovarik, J.1
Boudny, V.2
Kocak, I.3
Lauerova, L.4
Fait, V.5
Vagundova, M.6
-
20
-
-
0032127465
-
Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation
-
Kovarik P, Stoiber D, Novy M, Decker T. Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation. EMBO J 1998; 17:3660-3668.
-
(1998)
EMBO J
, vol.17
, pp. 3660-3668
-
-
Kovarik, P.1
Stoiber, D.2
Novy, M.3
Decker, T.4
-
21
-
-
0036789933
-
p38 MAPK enhances STAT 1-dependent transcription independently of Ser-727 phosphorylation
-
Ramsauer K, Sadzak I, Porras A, Pilz A, Nebreda AR, Decker T, Kovarik P. p38 MAPK enhances STAT 1-dependent transcription independently of Ser-727 phosphorylation. Proc Natl Acad Sci USA 2002; 99:12859-12864.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12859-12864
-
-
Ramsauer, K.1
Sadzak, I.2
Porras, A.3
Pilz, A.4
Nebreda, A.R.5
Decker, T.6
Kovarik, P.7
-
22
-
-
0038441502
-
Phosphorylation of the Stat1 transactivating domain is required for the response to type I interferons
-
Pilz A, Ramsauer K, Heidari H, Leitges M, Kovarik P, Decker T. Phosphorylation of the Stat1 transactivating domain is required for the response to type I interferons. EMBO Rep 2003; 4:368-373.
-
(2003)
EMBO Rep
, vol.4
, pp. 368-373
-
-
Pilz, A.1
Ramsauer, K.2
Heidari, H.3
Leitges, M.4
Kovarik, P.5
Decker, T.6
-
23
-
-
0031581086
-
Cloning and characterization of novel CIS family genes
-
Masuhara M, Sakamoto H, Matsumoto A, Suzuki R, Yasukawa H, Mitsui K, et al. Cloning and characterization of novel CIS family genes. Biochem Biophys Res Commun 1997; 239:439-446.
-
(1997)
Biochem Biophys Res Commun
, vol.239
, pp. 439-446
-
-
Masuhara, M.1
Sakamoto, H.2
Matsumoto, A.3
Suzuki, R.4
Yasukawa, H.5
Mitsui, K.6
-
24
-
-
0036644335
-
Impaired IFN-gamma-dependent inflammatory responses in human keratinocytes overexpressing the suppressor of cytokine signaling 1
-
Federici M, Giustizieri ML, Scarponi C, Girolomoni G, Albanesi C. Impaired IFN-gamma-dependent inflammatory responses in human keratinocytes overexpressing the suppressor of cytokine signaling 1. J Immunol 2002; 169:434-442.
-
(2002)
J Immunol
, vol.169
, pp. 434-442
-
-
Federici, M.1
Giustizieri, M.L.2
Scarponi, C.3
Girolomoni, G.4
Albanesi, C.5
-
25
-
-
0037108433
-
Constitutive expression of SOCS 3 confers resistance to IFN alpha in chronic myelogenous leukemia cells
-
Sakai I, Takeuchi K, Yamauchi H, Narumi H, Fujita S. Constitutive expression of SOCS 3 confers resistance to IFN alpha in chronic myelogenous leukemia cells. Blood 2002; 100:2926-2931.
-
(2002)
Blood
, vol.100
, pp. 2926-2931
-
-
Sakai, I.1
Takeuchi, K.2
Yamauchi, H.3
Narumi, H.4
Fujita, S.5
-
26
-
-
1842741016
-
Analysis of SOCS 3 promoter responses to interferon gamma
-
Gatto L, Berlato C, Poli V, Tininini S, Kinjyo I, Yoshimura A, et al. Analysis of SOCS 3 promoter responses to interferon gamma. J Biol Chem 2004; 279:13746-13754.
-
(2004)
J Biol Chem
, vol.279
, pp. 13746-13754
-
-
Gatto, L.1
Berlato, C.2
Poli, V.3
Tininini, S.4
Kinjyo, I.5
Yoshimura, A.6
-
27
-
-
0036731485
-
STATs: Transcriptional control and biological impact
-
Levy DE, Darnell JE Jr. STATs: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002; 3:651-662.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell Jr., J.E.2
-
28
-
-
0030712998
-
Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT 1, STAT 2, and p48-ISGF3gamma
-
Wong LH, Krauer KG, Hatzinisiriou I, Estcourt MJ, Hersey P, Tam ND, et al. Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT 1, STAT 2, and p48-ISGF3gamma. J Biol Chem 1997; 272:28779-28785.
-
(1997)
J Biol Chem
, vol.272
, pp. 28779-28785
-
-
Wong, L.H.1
Krauer, K.G.2
Hatzinisiriou, I.3
Estcourt, M.J.4
Hersey, P.5
Tam, N.D.6
-
29
-
-
13244249577
-
Interferons alpha and gamma induce p53-dependent and p53-independent apoptosis, respectively
-
Porta C, Hadj-Slimane R, Nejmeddine M, Pampin M, Tovey MG, Espert L, et al. Interferons alpha and gamma induce p53-dependent and p53-independent apoptosis, respectively. Oncogene 2005; 24:605-615.
-
(2005)
Oncogene
, vol.24
, pp. 605-615
-
-
Porta, C.1
Hadj-Slimane, R.2
Nejmeddine, M.3
Pampin, M.4
Tovey, M.G.5
Espert, L.6
-
30
-
-
0035810953
-
Stat 1-independent regulation of gene expression in response to IFN-gamma
-
Ramana CV, Gil MP, Han Y, Ransohoff RM, Schreiber RD, Stark GR. Stat 1-independent regulation of gene expression in response to IFN-gamma. Proc Natl Acad Sci USA 2001; 98:6674-6679.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6674-6679
-
-
Ramana, C.V.1
Gil, M.P.2
Han, Y.3
Ransohoff, R.M.4
Schreiber, R.D.5
Stark, G.R.6
-
31
-
-
11844305684
-
Stat1-independent induction of SOCS 3 by interferon-gamma is mediated by sustained activation of Stat 3 in mouse embryonic fibroblasts
-
Ramana CV, Kumar A, Enelow R. Stat1-independent induction of SOCS 3 by interferon-gamma is mediated by sustained activation of Stat 3 in mouse embryonic fibroblasts. Biochem Biophys Res Commun 2005; 327:727-733.
-
(2005)
Biochem Biophys Res Commun
, vol.327
, pp. 727-733
-
-
Ramana, C.V.1
Kumar, A.2
Enelow, R.3
-
32
-
-
4644278484
-
Expression of SOCS 1, suppressor of cytokine signalling 1, in human melanoma
-
Li Z, Metze D, Nashan D, Muller-Tidow C, Serve HL, Poremba C, et al. Expression of SOCS 1, suppressor of cytokine signalling 1, in human melanoma. J Invest Dermatol 2004; 123:737-745.
-
(2004)
J Invest Dermatol
, vol.123
, pp. 737-745
-
-
Li, Z.1
Metze, D.2
Nashan, D.3
Muller-Tidow, C.4
Serve, H.L.5
Poremba, C.6
|