JAK/STAT signaling is associated with cardiac dysfunction during ischemia and reperfusion

Circulation

Volumn 104, Issue 3, 2001, Pages 325-329

  Mascareno, Eduardo ^a   El Shafei, Mohammed ^a   Maulik, Nilanjana ^b   Sato, M ^b   Guo, Yueling ^a   Das, Dipak K ^b   Siddiqui, M A Q ^a,c  

^a SUNY Downstate Medical Center   (United States)

^b UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^c SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

Angiotensin; Ischemia; Renin; Reperfusion; Signal transduction

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSINOGEN; JANUS KINASE; LOSARTAN; MESSENGER RNA; TYRPHOSTIN;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BINDING AFFINITY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HUMAN; MALE; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REPERFUSION;

EID: 0035902571     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.104.3.325     Document Type: Article

References (23)

1. Derangement in renin-angiotensin regulation in the pathogenesis of hypertension
2. Regression of increased left ventricular mass by antihypertensives
3. Angiotensin-converting enzyme DD genotype in patients with ischaemic or idiopathic dilated cardiomyopathy
4. 1 receptor subtype
5. Molecular signalling mechanisms controlling growth and function of cardiac fibroblasts
6. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro
7. Effects of an angiotensin II antagonist on ischemic and nonischemic isolated rat hearts
8. Bradykinin-dependent cardioprotective effects of losartan against ischemia and reperfusion in rat hearts
9. Use of losartan to examine the role of the cardiac renin-angiotensin system in myocardial dysfunction during ischemia and reperfusion
10. Signal transduction and activator of transcription (STAT) protein-dependent activation of angiotensinogen promoter: A cellular signal for hypertrophy in cardiac muscle
11. Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice
12. Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy
13. Cytokine receptor signaling
14. Leukemia inhibitory factor, a potent cardiac hypertrophic cytokine, activates the Jak/Stat pathway in rat cardiomyocytes
15. Cardiotrophin-I: A multifunctional cytokine that signals via LIF receptor Gp 130 dependent pathways
16. Active renin and angiotensinogen in cardiac interstitial fluid after myocardial infarction
17. Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
18. Improved 4- and 6-hour myocardial preservation by hypoxic preconditioning
19. Myocardial protection by preconditioning of heart with losartan, an angiotensin II type 1-receptor blocker: Implication of bradykinin-dependent and bradykinin-independent mechanisms
20. β-Adrenergic receptor subtypes differentially affect apoptosis in adult rat cardiomyocytes
21. Cardiotrophin-I increases angiotensin mRNA in rat cardiac myocytes through STAT3: An autocrine loop for hypertrophy
22. Mechanism of induced susceptibility to angiotensin II-induced apoptosis in ventricular cardiomyocytes of spontaneously hypertensive rats
23. Apoptosis induction and inhibition of cellular proliferation by angiotensin II: Possible implications and perspectives