Polyglutamine-expanded ataxin-7 decreases nuclear translocation of NF-κB p65 and impairs NF-κB activity by inhibiting proteasome activity of cerebellar neurons

Cellular Signalling

Volumn 19, Issue 3, 2007, Pages 573-581

  Wang, Hung Li ^a   He, Cai Ying ^a   Chou, An Hsun ^a,b   Yeh, Tu Hsueh ^b   Chen, Ying Ling ^a,c   Li, Allen H ^b  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Ataxin 7; Cerebellum; NF B; Polyglutamine expanded ataxin 7; Proteasome; Spinocerebellar ataxia type 7

Indexed keywords

ATAXIN 7; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CASPASE 9; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; POLYGLUTAMINE; PROTEASOME; PROTEIN BCL XL; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING AFFINITY; CELL CULTURE; CELL SURVIVAL; CEREBELLUM; CONTROLLED STUDY; CYTOSOL; DNA BINDING; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ADENOVIRIDAE; ANIMALS; CELL NUCLEUS; CELLS, CULTURED; CEREBELLUM; ESCHERICHIA COLI; GENETIC VECTORS; NERVE TISSUE PROTEINS; NEURONS; NF-KAPPA B; PEPTIDES; PLASMIDS; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; TRANSCRIPTION FACTOR RELA; TRANSFORMATION, GENETIC;

EID: 33846220180     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2006.08.006     Document Type: Article

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