-
2
-
-
0027369395
-
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
-
Sadlack B., Merz H., Schorle H., Schimpl A., Feller A.C., Horak I. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell. 75:1993;253-261.
-
(1993)
Cell
, vol.75
, pp. 253-261
-
-
Sadlack, B.1
Merz, H.2
Schorle, H.3
Schimpl, A.4
Feller, A.C.5
Horak, I.6
-
3
-
-
0028784289
-
Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
-
Willerford D.M., Chen J., Ferry J.A., Davidson L., Ma A., Alt F.W. Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity. 3:1995;521-530.
-
(1995)
Immunity
, vol.3
, pp. 521-530
-
-
Willerford, D.M.1
Chen, J.2
Ferry, J.A.3
Davidson, L.4
Ma, A.5
Alt, F.W.6
-
4
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn R., Lohler J., Rennick D., Rajewsky K., Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell. 75:1993;263-274.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
5
-
-
0028982242
-
Transforming growth factor-beta 1 null mice. An animal model for inflammatory disorders
-
Kulkarni A.B., Ward J.M., Yaswen L., Mackall C.L., Bauer S.R., Huh C.G., et al. Transforming growth factor-beta 1 null mice. An animal model for inflammatory disorders. Am J Pathol. 146:1995;264-275.
-
(1995)
Am J Pathol
, vol.146
, pp. 264-275
-
-
Kulkarni, A.B.1
Ward, J.M.2
Yaswen, L.3
MacKall, C.L.4
Bauer, S.R.5
Huh, C.G.6
-
6
-
-
0027922467
-
Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice
-
Mombaerts P., Mizoguchi E., Grusby M.J., Glimcher L.H., Bhan A.K., Tonegawa S. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell. 75:1993;274-282.
-
(1993)
Cell
, vol.75
, pp. 274-282
-
-
Mombaerts, P.1
Mizoguchi, E.2
Grusby, M.J.3
Glimcher, L.H.4
Bhan, A.K.5
Tonegawa, S.6
-
7
-
-
0027517545
-
Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice
-
Powrie F., Leach M.W., Mauze S., Caddle L.B., Coffman R.L. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. Int Immunol. 5:1993;1461-1471.
-
(1993)
Int Immunol
, vol.5
, pp. 1461-1471
-
-
Powrie, F.1
Leach, M.W.2
Mauze, S.3
Caddle, L.B.4
Coffman, R.L.5
-
8
-
-
0028972499
-
Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin
-
Hermiston M.L., Gordon J.I. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science. 270:1995;1203-1207.
-
(1995)
Science
, vol.270
, pp. 1203-1207
-
-
Hermiston, M.L.1
Gordon, J.I.2
-
9
-
-
0032534043
-
A novel model of inflammatory bowel disease: Mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis
-
Panwala C.M., Jones J.C., Viney J.L. A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. J Immunol. 161:1998;5733-5744.
-
(1998)
J Immunol
, vol.161
, pp. 5733-5744
-
-
Panwala, C.M.1
Jones, J.C.2
Viney, J.L.3
-
10
-
-
0034657336
-
The role of STATs in transcriptional control and their impact on cellular function
-
Bromberg J., Darnell J.E. The role of STATs in transcriptional control and their impact on cellular function. Oncogene. 19:2000;2468-2473.
-
(2000)
Oncogene
, vol.19
, pp. 2468-2473
-
-
Bromberg, J.1
Darnell, J.E.2
-
11
-
-
0034657958
-
Roles of STAT3 defined by tissue-specific gene targeting
-
Akira S. Roles of STAT3 defined by tissue-specific gene targeting. Oncogene. 19:2000;2607-2611.
-
(2000)
Oncogene
, vol.19
, pp. 2607-2611
-
-
Akira, S.1
-
12
-
-
0030935260
-
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
-
Takeda K., Noguchi K., Shi W., Tanaka T., Matsumoto M., Yoshida N., et al. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc Natl Acad Sci U S A. 94:1997;3801-3804.
-
(1997)
Proc Natl Acad Sci U S a
, vol.94
, pp. 3801-3804
-
-
Takeda, K.1
Noguchi, K.2
Shi, W.3
Tanaka, T.4
Matsumoto, M.5
Yoshida, N.6
-
13
-
-
0035131190
-
Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation in the liver
-
Alonzi T., Maritano D., Gorgoni B., Rizzuto G., Libert C., Poli V. Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation in the liver. Mol Cell Biol. 21:2001;1621-1632.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1621-1632
-
-
Alonzi, T.1
Maritano, D.2
Gorgoni, B.3
Rizzuto, G.4
Libert, C.5
Poli, V.6
-
15
-
-
0032539008
-
Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects
-
Betz U.A., Bloch W., van den Broek M., Yoshida K., Taga T., Kishimoto T., et al. Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects. J Exp Med. 188:1998;1955-1965.
-
(1998)
J Exp Med
, vol.188
, pp. 1955-1965
-
-
Betz, U.A.1
Bloch, W.2
Van Den Broek, M.3
Yoshida, K.4
Taga, T.5
Kishimoto, T.6
-
16
-
-
0035029433
-
A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent
-
Vooijs M., Jonkers J., Berns A. A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent. EMBO Rep. 2:2001;292-297.
-
(2001)
EMBO Rep
, vol.2
, pp. 292-297
-
-
Vooijs, M.1
Jonkers, J.2
Berns, A.3
-
17
-
-
0031057872
-
Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease
-
Parronchi P., Romagnani P., Annunziato F., Sampognaro S., Becchio A., Giannarini L., et al. Type 1 T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease. Am J Pathol. 150:1997;823-832.
-
(1997)
Am J Pathol
, vol.150
, pp. 823-832
-
-
Parronchi, P.1
Romagnani, P.2
Annunziato, F.3
Sampognaro, S.4
Becchio, A.5
Giannarini, L.6
-
18
-
-
0031568001
-
Induction and prevention of colonic inflammation in IL-2-deficient mice
-
Ehrhardt R.O., Ludviksson B.R., Gray B., Neurath M., Strober W. Induction and prevention of colonic inflammation in IL-2-deficient mice. J Immunol. 158:1997;566-573.
-
(1997)
J Immunol
, vol.158
, pp. 566-573
-
-
Ehrhardt, R.O.1
Ludviksson, B.R.2
Gray, B.3
Neurath, M.4
Strober, W.5
-
19
-
-
0032530697
-
IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice
-
Davidson N.J., Hudak S.A., Lesley R.E., Menon S., Leach M.W., Rennick D.M. IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice. J Immunol. 161:1998;3143-3149.
-
(1998)
J Immunol
, vol.161
, pp. 3143-3149
-
-
Davidson, N.J.1
Hudak, S.A.2
Lesley, R.E.3
Menon, S.4
Leach, M.W.5
Rennick, D.M.6
-
20
-
-
0026047091
-
The role of interferon alpha/beta in the induction of intestinal pathology in mice
-
Garside P., Felstein M.V., Green E.A., Mowat A.M. The role of interferon alpha/beta in the induction of intestinal pathology in mice. Immunology. 74:1991;279-283.
-
(1991)
Immunology
, vol.74
, pp. 279-283
-
-
Garside, P.1
Felstein, M.V.2
Green, E.A.3
Mowat, A.M.4
-
21
-
-
0033034365
-
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
-
Takeda K., Clausen B.E., Kaisho T., Tsujimura T., Terada N., Forster I., et al. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity. 10:1999;39-49.
-
(1999)
Immunity
, vol.10
, pp. 39-49
-
-
Takeda, K.1
Clausen, B.E.2
Kaisho, T.3
Tsujimura, T.4
Terada, N.5
Forster, I.6
-
22
-
-
0037452789
-
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity
-
Welte T., Zhang S.S., Wang T., Zhang Z., Hesslein D.G., Yin Z., et al. STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc Natl Acad Sci U S A. 100:2003;1879-1884.
-
(2003)
Proc Natl Acad Sci U S a
, vol.100
, pp. 1879-1884
-
-
Welte, T.1
Zhang, S.S.2
Wang, T.3
Zhang, Z.4
Hesslein, D.G.5
Yin, Z.6
-
23
-
-
0033523019
-
Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action
-
Riley J.K., Takeda K., Akira S., Schreiber R.D. Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action. J Biol Chem. 274:1999;16513-16521.
-
(1999)
J Biol Chem
, vol.274
, pp. 16513-16521
-
-
Riley, J.K.1
Takeda, K.2
Akira, S.3
Schreiber, R.D.4
-
24
-
-
0030917254
-
Interleukin-11: Review of molecular, cell biology, and clinical use
-
Du X., Williams D.A. Interleukin-11: review of molecular, cell biology, and clinical use. Blood. 89:1997;3897-3908.
-
(1997)
Blood
, vol.89
, pp. 3897-3908
-
-
Du, X.1
Williams, D.A.2
-
25
-
-
0035898315
-
Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation
-
Ernst M., Inglese M., Waring P., Campbell I.K., Bao S., Clay F.J., et al. Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation. J Exp Med. 194:2001;189-203.
-
(2001)
J Exp Med
, vol.194
, pp. 189-203
-
-
Ernst, M.1
Inglese, M.2
Waring, P.3
Campbell, I.K.4
Bao, S.5
Clay, F.J.6
-
26
-
-
0036796060
-
Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice
-
Tebbutt N.C., Giraud A.S., Inglese M., Jenkins B., Waring P., Clay F.J., et al. Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice. Nat Med. 8:2002;1089-1097.
-
(2002)
Nat Med
, vol.8
, pp. 1089-1097
-
-
Tebbutt, N.C.1
Giraud, A.S.2
Inglese, M.3
Jenkins, B.4
Waring, P.5
Clay, F.J.6
-
27
-
-
18344410191
-
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo
-
Atreya R., Mudter J., Finotto S., Mullberg J., Jostock T., Wirtz S., et al. Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in Crohn disease and experimental colitis in vivo. Nat Med. 6:2000;583-588.
-
(2000)
Nat Med
, vol.6
, pp. 583-588
-
-
Atreya, R.1
Mudter, J.2
Finotto, S.3
Mullberg, J.4
Jostock, T.5
Wirtz, S.6
-
28
-
-
0032576359
-
Acquired increase in leucocyte binding by intestinal microvascular endothelium in inflammatory bowel disease
-
Binion D.G., West G.A., Volk E.E., Drazba J.A., Ziats N.P., Petras R.E., et al. Acquired increase in leucocyte binding by intestinal microvascular endothelium in inflammatory bowel disease. Lancet. 352:1998;1742-1746.
-
(1998)
Lancet
, vol.352
, pp. 1742-1746
-
-
Binion, D.G.1
West, G.A.2
Volk, E.E.3
Drazba, J.A.4
Ziats, N.P.5
Petras, R.E.6
-
30
-
-
0033402848
-
Monocyte chemoattractant protein 1-dependent leukocytic infiltrates are responsible for autoimmune disease in MRL-Fas(lpr) mice
-
Tesch G.H., Maifert S., Schwarting A., Rollins B.J., Kelley V.R. Monocyte chemoattractant protein 1-dependent leukocytic infiltrates are responsible for autoimmune disease in MRL-Fas(lpr) mice. J Exp Med. 190:1999;1813-1824.
-
(1999)
J Exp Med
, vol.190
, pp. 1813-1824
-
-
Tesch, G.H.1
Maifert, S.2
Schwarting, A.3
Rollins, B.J.4
Kelley, V.R.5
-
31
-
-
0037799912
-
Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice
-
Kobayashi M., Kweon M.N., Kuwata H., Schreiber R.D., Kiyono H., Takeda K., et al. Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice. J Clin Invest. 111:2003;1297-1308.
-
(2003)
J Clin Invest
, vol.111
, pp. 1297-1308
-
-
Kobayashi, M.1
Kweon, M.N.2
Kuwata, H.3
Schreiber, R.D.4
Kiyono, H.5
Takeda, K.6
-
32
-
-
0033556011
-
Immune events associated with the cure of established tumors and spontaneous metastases by local and systemic interleukin 12
-
Cavallo F., Di Carlo E., Butera M., Verrua R., Colombo M.P., Musiani P., et al. Immune events associated with the cure of established tumors and spontaneous metastases by local and systemic interleukin 12. Cancer Res. 59:1999;414-421.
-
(1999)
Cancer Res
, vol.59
, pp. 414-421
-
-
Cavallo, F.1
Di Carlo, E.2
Butera, M.3
Verrua, R.4
Colombo, M.P.5
Musiani, P.6
-
33
-
-
0027507239
-
Neutrophil-mediated damage to human vascular endothelium. Role of cytokine activation
-
Westlin W.F., Gimbrone M.A. Neutrophil-mediated damage to human vascular endothelium. Role of cytokine activation. Am J Pathol. 142:1993;117-128.
-
(1993)
Am J Pathol
, vol.142
, pp. 117-128
-
-
Westlin, W.F.1
Gimbrone, M.A.2
-
34
-
-
0035102228
-
STAT-3 activation is required for normal G-CSF-dependent proliferation and granulocytic differentiation
-
McLemore M.L., Grewal S., Liu F., Archambault A., Poursine-Laurent J., Haug J., et al. STAT-3 activation is required for normal G-CSF-dependent proliferation and granulocytic differentiation. Immunity. 14:2001;193-204.
-
(2001)
Immunity
, vol.14
, pp. 193-204
-
-
McLemore, M.L.1
Grewal, S.2
Liu, F.3
Archambault, A.4
Poursine-Laurent, J.5
Haug, J.6
-
35
-
-
0025690778
-
Role of intestinal microflora in initiation and perpetuation of inflammatory bowel disease
-
Sartor R.B. Role of intestinal microflora in initiation and perpetuation of inflammatory bowel disease. Can J Gastroenterol. 4:1990;271-277.
-
(1990)
Can J Gastroenterol
, vol.4
, pp. 271-277
-
-
Sartor, R.B.1
-
36
-
-
0028987562
-
Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice
-
Wysocka M., Kubin M., Vieira L.Q., Ozmen L., Garotta G., Scott P., et al. Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Eur J Immunol. 25:1995;672-676.
-
(1995)
Eur J Immunol
, vol.25
, pp. 672-676
-
-
Wysocka, M.1
Kubin, M.2
Vieira, L.Q.3
Ozmen, L.4
Garotta, G.5
Scott, P.6
-
37
-
-
0023270053
-
CD4 monoclonal antibody pairs for immunosuppression and tolerance induction
-
Qin S., Cobbold S., Tighe H., Benjamin R., Waldmann H. CD4 monoclonal antibody pairs for immunosuppression and tolerance induction. Eur J Immunol. 17:1987;1159-1165.
-
(1987)
Eur J Immunol
, vol.17
, pp. 1159-1165
-
-
Qin, S.1
Cobbold, S.2
Tighe, H.3
Benjamin, R.4
Waldmann, H.5
-
38
-
-
0014253825
-
Antibiotic decontamination of the digestive tract of mice. Technical procedures
-
van der Waaij D., Sturm C.A. Antibiotic decontamination of the digestive tract of mice. Technical procedures. Lab Anim Care. 18:1968;1-10.
-
(1968)
Lab Anim Care
, vol.18
, pp. 1-10
-
-
Van Der Waaij, D.1
Sturm, C.A.2
-
39
-
-
0008771783
-
Murine macrophages: Isolation, cultivation and characterization
-
L.A. Herzenberg, D.M. Weir, & L.A. Herzenberg. Boston: Blackwell C. Blackwell Science
-
Doyle A.G., Fraser I.P. Murine macrophages: isolation, cultivation and characterization. Herzenberg L.A., Weir D.M., Herzenberg L.A. Weir's handbook of experimental immunology. 1996;154.1-154.8 Blackwell C. Blackwell Science, Boston.
-
(1996)
Weir's Handbook of Experimental Immunology
, pp. 1541-1548
-
-
Doyle, A.G.1
Fraser, I.P.2
-
40
-
-
0029813545
-
Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses
-
Berg D.J., Davidson N., Kuhn R., Muller W., Menon S., Holland G., et al. Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J Clin Invest. 98:1996;1010-1020.
-
(1996)
J Clin Invest
, vol.98
, pp. 1010-1020
-
-
Berg, D.J.1
Davidson, N.2
Kuhn, R.3
Muller, W.4
Menon, S.5
Holland, G.6
-
41
-
-
0034326620
-
DNA vaccination against rat her-2/Neu p185 more effectively inhibits carcinogenesis than transplantable carcinomas in transgenic BALB/c mice
-
Rovero S., Amici A., Carlo E.D., Bei R., Nanni P., Quaglino E., et al. DNA vaccination against rat her-2/Neu p185 more effectively inhibits carcinogenesis than transplantable carcinomas in transgenic BALB/c mice. J Immunol. 165:2000;5133-5142.
-
(2000)
J Immunol
, vol.165
, pp. 5133-5142
-
-
Rovero, S.1
Amici, A.2
Carlo, E.D.3
Bei, R.4
Nanni, P.5
Quaglino, E.6
-
42
-
-
0034665093
-
The combined action of IL-15 and IL-12 gene transfer can induce tumor cell rejection without T and NK cell involvement
-
Di Carlo E., Comes A., Basso S., De Ambrosis A., Meazza R., Musiani P., et al. The combined action of IL-15 and IL-12 gene transfer can induce tumor cell rejection without T and NK cell involvement. J Immunol. 165:2000;3111-3118.
-
(2000)
J Immunol
, vol.165
, pp. 3111-3118
-
-
Di Carlo, E.1
Comes, A.2
Basso, S.3
De Ambrosis, A.4
Meazza, R.5
Musiani, P.6
|