Inhibition of pp60(c-Src) reduces Bcl-X(L) expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors

Oncogene

Volumn 18, Issue 33, 1999, Pages 4654-4662

  Karni, Rotem ^a   Jove, Richard ^b   Levitzki, Alexander ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

Bcl X; c Src; EGFR; HER 2

Indexed keywords

COMPLEMENTARY RNA; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; LUCIFERASE; PHOSPHOTRANSFERASE; PROTEIN BCL X; STAT3 PROTEIN; COMPLEMENTARY DNA; DNA BINDING PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR 1; PROTEIN; PROTEIN BCL 2; PROTEIN KINASE P60; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER GENETICS; CARCINOGENESIS; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; ONCOGENE NEU; ONCOGENE SRC; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; REPORTER GENE; SIGNAL TRANSDUCTION; BIOSYNTHESIS; CELL TRANSFORMATION; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION; GENETICS; METABOLISM;

ANIMALIA;

BCL-X PROTEIN; CELL TRANSFORMATION, NEOPLASTIC; DNA, ANTISENSE; DNA-BINDING PROTEINS; GENE EXPRESSION; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS;

EID: 0033584297     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202835     Document Type: Article

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