메뉴 건너뛰기




Volumn 56, Issue 4, 2006, Pages 425-446

Wnt gradient formation: From source to sink

Author keywords

Morphogen gradient; Wingless; Wnt

Indexed keywords

EMBRYO; FLY; LIGAND; MORPHOGENESIS; PROTEIN;

EID: 33845350848     PISSN: 15707555     EISSN: None     Source Type: Journal    
DOI: 10.1163/157075606778967793     Document Type: Conference Paper
Times cited : (1)

References (81)
  • 2
    • 0035152025 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless
    • Baeg, G.H., Lin, X., Khare, N., Baumgartner, S. & Perrimon, N. (2001) Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development, 1, 87-94.
    • (2001) Development , vol.1 , pp. 87-94
    • Baeg, G.H.1    Lin, X.2    Khare, N.3    Baumgartner, S.4    Perrimon, N.5
  • 3
    • 0028842141 scopus 로고
    • Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface
    • Bejsovec, A. & Wieschaus, E. (1995) Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface. Genetics, 1, 309-320.
    • (1995) Genetics , vol.1 , pp. 309-320
    • Bejsovec, A.1    Wieschaus, E.2
  • 5
    • 0032577556 scopus 로고    scopus 로고
    • Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing
    • Cadigan, K.M., Fish, M.P., Rulifson, E.J. & Nusse, R. (1998) Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing. Cell, 5, 767-777.
    • (1998) Cell , vol.5 , pp. 767-777
    • Cadigan, K.M.1    Fish, M.P.2    Rulifson, E.J.3    Nusse, R.4
  • 6
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: A common theme in animal development
    • Cadigan, K.M. & Nusse, R. (1997) Wnt signaling: A common theme in animal development. Genes Dev., 24, 3286-3305.
    • (1997) Genes Dev. , vol.24 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 8
    • 0035860538 scopus 로고    scopus 로고
    • Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal
    • Chamoun, Z., Mann, R.K., Nellen, D., von Kessler, D.P., Bellotto, M., Beachy, P.A. & Basler, K. (2001) Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal. Science, 5537, 2080-2084.
    • (2001) Science , vol.5537 , pp. 2080-2084
    • Chamoun, Z.1    Mann, R.K.2    Nellen, D.3    von Kessler, D.P.4    Bellotto, M.5    Beachy, P.A.6    Basler, K.7
  • 9
    • 1842853184 scopus 로고    scopus 로고
    • Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates
    • Chen, M.H., Li, Y.J., Kawakami, T., Xu, S.M. & Chuang, P.T. (2004) Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates. Genes Dev., 6, 641-659.
    • (2004) Genes Dev. , vol.6 , pp. 641-659
    • Chen, M.H.1    Li, Y.J.2    Kawakami, T.3    Xu, S.M.4    Chuang, P.T.5
  • 10
    • 0030297553 scopus 로고    scopus 로고
    • Dual roles for patched in sequestering and transducing Hedgehog
    • Chen, Y. & Struhl, G. (1996) Dual roles for patched in sequestering and transducing Hedgehog. Cell, 3, 553-563.
    • (1996) Cell , vol.3 , pp. 553-563
    • Chen, Y.1    Struhl, G.2
  • 11
    • 0029240522 scopus 로고
    • Morphogens in vertebrate development: How do they work?
    • Cooke, J. (1995) Morphogens in vertebrate development: How do they work? Bioessays, 2, 93-96.
    • (1995) Bioessays , vol.2 , pp. 93-96
    • Cooke, J.1
  • 12
    • 18744400798 scopus 로고    scopus 로고
    • Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
    • Daniels, D.L. & Weis, W.I. (2005) Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation. Nat. Struct. Mol. Biol., 4, 364-371.
    • (2005) Nat. Struct. Mol. Biol. , vol.4 , pp. 364-371
    • Daniels, D.L.1    Weis, W.I.2
  • 13
    • 0032745206 scopus 로고    scopus 로고
    • A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates wnt-1 signaling
    • Dennis, S., Aikawa, M., Szeto, W., d'Amore, P.A. & Papkoff, J. (1999) A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates wnt-1 signaling. J. Cell Sci., 112, 3815-3820.
    • (1999) J. Cell Sci. , vol.112 , pp. 3815-3820
    • Dennis, S.1    Aikawa, M.2    Szeto, W.3    d'Amore, P.A.4    Papkoff, J.5
  • 14
    • 0035067146 scopus 로고    scopus 로고
    • Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region
    • Dorfman, R. & Shilo, B.Z. (2001) Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region. Development, 6, 965-972.
    • (2001) Development , vol.6 , pp. 965-972
    • Dorfman, R.1    Shilo, B.Z.2
  • 15
    • 0028929367 scopus 로고
    • Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos
    • Du, S.J., Purcell, S.M., Christian, J.L., McGrew, L.L. & Moon, R.T. (1995) Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos. Mol. Cell Biol., 5, 2625-2634.
    • (1995) Mol. Cell Biol. , vol.5 , pp. 2625-2634
    • Du, S.J.1    Purcell, S.M.2    Christian, J.L.3    McGrew, L.L.4    Moon, R.T.5
  • 16
    • 0035368514 scopus 로고    scopus 로고
    • Regulated endocytic routing modulates wingless signaling in Drosophila embryos
    • Dubois, L., Lecourtois, M., Alexandre, C., Hirst, E. & Vincent, J.P. (2001) Regulated endocytic routing modulates wingless signaling in Drosophila embryos. Cell, 5, 613-624.
    • (2001) Cell , vol.5 , pp. 613-624
    • Dubois, L.1    Lecourtois, M.2    Alexandre, C.3    Hirst, E.4    Vincent, J.P.5
  • 17
    • 0032524323 scopus 로고    scopus 로고
    • The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors
    • Dyson, S. & Gurdon, J.B. (1998) The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. Cell, 4, 557-568.
    • (1998) Cell , vol.4 , pp. 557-568
    • Dyson, S.1    Gurdon, J.B.2
  • 18
    • 0033625428 scopus 로고    scopus 로고
    • Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development
    • Faure, S., Lee, M.A., Keller, T., ten Dijke, P. & Whitman, M. (2000) Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development. Development, 13, 2917-2931.
    • (2000) Development , vol.13 , pp. 2917-2931
    • Faure, S.1    Lee, M.A.2    Keller, T.3    ten Dijke, P.4    Whitman, M.5
  • 19
    • 0037321854 scopus 로고    scopus 로고
    • Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog
    • Gallet, A., Rodriguez, R., Ruel, L. & Therond, P.P. (2003) Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog. Dev. Cell, 2, 191-204.
    • (2003) Dev. Cell , vol.2 , pp. 191-204
    • Gallet, A.1    Rodriguez, R.2    Ruel, L.3    Therond, P.P.4
  • 20
    • 9644264342 scopus 로고    scopus 로고
    • Temporal modulation of the Hedgehog morphogen gradient by a patched-dependent targeting to lysosomal compartment
    • Gallet, A. & Therond, P.P. (2005) Temporal modulation of the Hedgehog morphogen gradient by a patched-dependent targeting to lysosomal compartment. Dev. Biol., 1, 51-62.
    • (2005) Dev. Biol. , vol.1 , pp. 51-62
    • Gallet, A.1    Therond, P.P.2
  • 21
    • 0036570660 scopus 로고    scopus 로고
    • Wingful, an extracellular feedback inhibitor of Wingless
    • Gerlitz, O. & Basler, K. (2002) Wingful, an extracellular feedback inhibitor of Wingless. Genes Dev., 9, 1055-1059.
    • (2002) Genes Dev. , vol.9 , pp. 1055-1059
    • Gerlitz, O.1    Basler, K.2
  • 22
    • 0036111641 scopus 로고    scopus 로고
    • HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient
    • Giraldez, A.J., Copley, R.R. & Cohen, S.M. (2002) HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient. Dev. Cell, 5, 667-676.
    • (2002) Dev. Cell , vol.5 , pp. 667-676
    • Giraldez, A.J.1    Copley, R.R.2    Cohen, S.M.3
  • 23
    • 13244292984 scopus 로고    scopus 로고
    • Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog
    • Glise, B., Miller, C.A., Crozatier, M., Halbisen, M.A., Wise, S., Olson, D.J., Vincent, A. & Blair, S.S. (2005) Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog. Dev. Cell, 2, 255-266.
    • (2005) Dev. Cell , vol.2 , pp. 255-266
    • Glise, B.1    Miller, C.A.2    Crozatier, M.3    Halbisen, M.A.4    Wise, S.5    Olson, D.J.6    Vincent, A.7    Blair, S.S.8
  • 24
    • 0025744384 scopus 로고
    • Secretion and movement of wingless protein in the epidermis of the Drosophila embryo
    • Gonzalez, F., Swales, L., Bejsovec, A., Skaer, H. & Martinez Arias, A. (1991) Secretion and movement of wingless protein in the epidermis of the Drosophila embryo. Mech. Dev., 1, 43-54.
    • (1991) Mech. Dev. , vol.1 , pp. 43-54
    • Gonzalez, F.1    Swales, L.2    Bejsovec, A.3    Skaer, H.4    Martinez Arias, A.5
  • 25
    • 13244257603 scopus 로고    scopus 로고
    • The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog
    • Gorfinkiel, N., Sierra, J., Callejo, A., Ibanez, C. & Guerrero, I. (2005) The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog. Dev. Cell, 2, 241-253.
    • (2005) Dev. Cell , vol.2 , pp. 241-253
    • Gorfinkiel, N.1    Sierra, J.2    Callejo, A.3    Ibanez, C.4    Guerrero, I.5
  • 26
    • 0029940972 scopus 로고    scopus 로고
    • Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily
    • Graff, J.M., Bansal, A. & Melton, D.A. (1996) Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily. Cell, 4, 479-487.
    • (1996) Cell , vol.4 , pp. 479-487
    • Graff, J.M.1    Bansal, A.2    Melton, D.A.3
  • 27
    • 0035823004 scopus 로고    scopus 로고
    • Argosomes: A potential vehicle for the spread of morphogens through epithelia
    • Greco, V., Hannus, M. & Eaton, S. (2001) Argosomes: A potential vehicle for the spread of morphogens through epithelia. Cell, 5, 633-645.
    • (2001) Cell , vol.5 , pp. 633-645
    • Greco, V.1    Hannus, M.2    Eaton, S.3
  • 29
    • 0342299882 scopus 로고    scopus 로고
    • The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis
    • Hacker, U., Lin, X. & Perrimon, N. (1997) The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development, 18, 3565-3573.
    • (1997) Development , vol.18 , pp. 3565-3573
    • Hacker, U.1    Lin, X.2    Perrimon, N.3
  • 30
    • 0030885710 scopus 로고    scopus 로고
    • Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila
    • Haerry, T.E., Heslip, T.R., Marsh, J.L. & O'Connor, M.B. (1997) Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila. Development, 16, 3055-3064.
    • (1997) Development , vol.16 , pp. 3055-3064
    • Haerry, T.E.1    Heslip, T.R.2    Marsh, J.L.3    O'Connor, M.B.4
  • 31
    • 14844365003 scopus 로고    scopus 로고
    • Drosophila glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc
    • Han, C., Yan, D., Belenkaya, T.Y. & Lin, X. (2005) Drosophila glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc. Development, 4, 667-679.
    • (2005) Development , vol.4 , pp. 667-679
    • Han, C.1    Yan, D.2    Belenkaya, T.Y.3    Lin, X.4
  • 33
    • 0034161499 scopus 로고    scopus 로고
    • A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling
    • Hofmann, K. (2000) A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling. Trends Biochem. Sci., 3, 111-112.
    • (2000) Trends Biochem. Sci. , vol.3 , pp. 111-112
    • Hofmann, K.1
  • 34
    • 0029844213 scopus 로고    scopus 로고
    • Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos
    • Hoppler, S., Brown, J.D. & Moon, R.T. (1996) Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos. Genes Dev., 21, 2805-2817.
    • (1996) Genes Dev. , vol.21 , pp. 2805-2817
    • Hoppler, S.1    Brown, J.D.2    Moon, R.T.3
  • 36
    • 0030450052 scopus 로고    scopus 로고
    • The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing
    • Kadowaki, T., Wilder, E., Klingensmith, J., Zachary, K. & Perrimon, N. (1996) The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes Dev., 24, 3116-3128.
    • (1996) Genes Dev. , vol.24 , pp. 3116-3128
    • Kadowaki, T.1    Wilder, E.2    Klingensmith, J.3    Zachary, K.4    Perrimon, N.5
  • 37
    • 5044250261 scopus 로고    scopus 로고
    • Spatial regulation of Wingless morphogen distribution and signaling by Dally-like protein
    • Kirkpatrick, C.A., Dimitroff, B.D., Rawson, J.M. & Selleck, S.B. (2004) Spatial regulation of Wingless morphogen distribution and signaling by Dally-like protein. Dev. Cell, 4, 513-523.
    • (2004) Dev. Cell , vol.4 , pp. 513-523
    • Kirkpatrick, C.A.1    Dimitroff, B.D.2    Rawson, J.M.3    Selleck, S.B.4
  • 38
    • 5044249440 scopus 로고    scopus 로고
    • Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity
    • Kreuger, J., Perez, L., Giraldez, A.J. & Cohen, S.M. (2004) Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity. Dev. Cell, 4, 503-512.
    • (2004) Dev. Cell , vol.4 , pp. 503-512
    • Kreuger, J.1    Perez, L.2    Giraldez, A.J.3    Cohen, S.M.4
  • 39
    • 0030604688 scopus 로고    scopus 로고
    • Morphogens, compartments, and pattern: Lessons from drosophila?
    • Lawrence, P.A. & Struhl, G. (1996) Morphogens, compartments, and pattern: Lessons from drosophila? Cell, 7, 951-961.
    • (1996) Cell , vol.7 , pp. 951-961
    • Lawrence, P.A.1    Struhl, G.2
  • 40
    • 0032425036 scopus 로고    scopus 로고
    • Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc
    • Lecuit, T. & Cohen, S.M. (1998) Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc. Development, 24, 4901-4907.
    • (1998) Development , vol.24 , pp. 4901-4907
    • Lecuit, T.1    Cohen, S.M.2
  • 41
    • 0033566126 scopus 로고    scopus 로고
    • Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling
    • Lin, X. & Perrimon, N. (1999) Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling. Nature, 6741, 281-284.
    • (1999) Nature , vol.6741 , pp. 281-284
    • Lin, X.1    Perrimon, N.2
  • 42
    • 0042131956 scopus 로고    scopus 로고
    • A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor
    • Liu, G., Bafico, A., Harris, V.K. & Aaronson, S.A. (2003) A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor. Mol. Cell Biol., 16, 5825-5835.
    • (2003) Mol. Cell Biol. , vol.16 , pp. 5825-5835
    • Liu, G.1    Bafico, A.2    Harris, V.K.3    Aaronson, S.A.4
  • 43
    • 0032960350 scopus 로고    scopus 로고
    • A Wnt signaling pathway controls hox gene expression and neuroblast migration in C. elegans
    • Maloof, J.N., Whangbo, J., Harris, J.M., Jongeward, G.D. & Kenyon, C. (1999) A Wnt signaling pathway controls hox gene expression and neuroblast migration in C. elegans. Development, 1, 37-49.
    • (1999) Development , vol.1 , pp. 37-49
    • Maloof, J.N.1    Whangbo, J.2    Harris, J.M.3    Jongeward, G.D.4    Kenyon, C.5
  • 44
    • 18244427021 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
    • Mao, J., Wang, J., Liu, B., Pan, W., Farr 3rd, G.H., Flynn, C., Yuan, H., Takada, S., Kimelman, D., Li, L. & Wu, D. (2001) Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol. Cell., 4, 801-809.
    • (2001) Mol. Cell. , vol.4 , pp. 801-809
    • Mao, J.1    Wang, J.2    Liu, B.3    Pan, W.4    Farr III, G.H.5    Flynn, C.6    Yuan, H.7    Takada, S.8    Kimelman, D.9    Li, L.10    Wu, D.11
  • 45
    • 30644480899 scopus 로고    scopus 로고
    • The endocytic pathway and formation of the Wingless morphogen gradient
    • Marois, E., Mahmoud, A. & Eaton, S. (2006) The endocytic pathway and formation of the Wingless morphogen gradient. Development, 2, 307-317.
    • (2006) Development , vol.2 , pp. 307-317
    • Marois, E.1    Mahmoud, A.2    Eaton, S.3
  • 46
    • 0027097821 scopus 로고
    • Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line
    • Mason, J.O., Kitajewski, J. & Varmus, H.E. (1992) Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line. Mol. Biol. Cell, 5, 521-533.
    • (1992) Mol. Biol. Cell , vol.5 , pp. 521-533
    • Mason, J.O.1    Kitajewski, J.2    Varmus, H.E.3
  • 47
    • 0031239988 scopus 로고    scopus 로고
    • Activin has direct long-range signalling activity and can form a concentration gradient by diffusion
    • McDowell, N., Zorn, A.M., Crease, D.J. & Gurdon, J.B. (1997) Activin has direct long-range signalling activity and can form a concentration gradient by diffusion. Curr. Biol., 9, 671-681.
    • (1997) Curr. Biol. , vol.9 , pp. 671-681
    • McDowell, N.1    Zorn, A.M.2    Crease, D.J.3    Gurdon, J.B.4
  • 48
    • 0036153448 scopus 로고    scopus 로고
    • The Wnts
    • Reviews3001
    • Miller, J.R. (2002) The Wnts. Genome Biol., 3(1), Reviews3001.
    • (2002) Genome Biol. , vol.3 , Issue.1
    • Miller, J.R.1
  • 49
    • 0032568795 scopus 로고    scopus 로고
    • Coordination of growth and cell division in the Drosophila wing
    • Neufeld, T.P., de la Cruz, A.F., Johnston, L.A. & Edgar, B.A. (1998) Coordination of growth and cell division in the Drosophila wing. Cell, 7, 1183-1193.
    • (1998) Cell , vol.7 , pp. 1183-1193
    • Neufeld, T.P.1    de la Cruz, A.F.2    Johnston, L.A.3    Edgar, B.A.4
  • 50
    • 0031020656 scopus 로고    scopus 로고
    • Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing
    • Neumann, C.J. & Cohen, S.M. (1997) Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing. Development, 4, 871-880.
    • (1997) Development , vol.4 , pp. 871-880
    • Neumann, C.J.1    Cohen, S.M.2
  • 51
    • 0032514852 scopus 로고    scopus 로고
    • Interpretation of a BMP activity gradient in Drosophila embryos depends on synergistic signaling by two type I receptors, SAX and TKV
    • Nguyen, M., Park, S., Marques, G. & Arora, K. (1998) Interpretation of a BMP activity gradient in Drosophila embryos depends on synergistic signaling by two type I receptors, SAX and TKV. Cell, 4, 495-506.
    • (1998) Cell , vol.4 , pp. 495-506
    • Nguyen, M.1    Park, S.2    Marques, G.3    Arora, K.4
  • 52
    • 0344464720 scopus 로고    scopus 로고
    • Wnts and Hedgehogs: Lipid-modified proteins and similarities in signaling mechanisms at the cell surface
    • Nusse, R. (2003) Wnts and Hedgehogs: Lipid-modified proteins and similarities in signaling mechanisms at the cell surface. Development, 22, 5297-5305.
    • (2003) Development , vol.22 , pp. 5297-5305
    • Nusse, R.1
  • 53
    • 18344378499 scopus 로고    scopus 로고
    • Lipoprotein particles are required for Hedgehog and Wingless signalling
    • Panakova, D., Sprong, H., Marois, E., Thiele, C. & Eaton, S. (2005) Lipoprotein particles are required for Hedgehog and Wingless signalling. Nature, 7038, 58-65.
    • (2005) Nature , vol.7038 , pp. 58-65
    • Panakova, D.1    Sprong, H.2    Marois, E.3    Thiele, C.4    Eaton, S.5
  • 54
    • 0033598401 scopus 로고    scopus 로고
    • Casein kinase I transduces Wnt signals
    • Peters, J.M., McKay, R.M., McKay, J.P. & Graff, J.M. (1999) Casein kinase I transduces Wnt signals. Nature, 6751, 345-350.
    • (1999) Nature , vol.6751 , pp. 345-350
    • Peters, J.M.1    McKay, R.M.2    McKay, J.P.3    Graff, J.M.4
  • 55
    • 0034704842 scopus 로고    scopus 로고
    • The progeny of wingless-expressing cells deliver the signal at a distance in Drosophila embryos
    • Pfeiffer, S., Alexandre, C., Calleja, M. & Vincent, J.P. (2000) The progeny of wingless-expressing cells deliver the signal at a distance in Drosophila embryos. Curr. Biol., 6, 321-324.
    • (2000) Curr. Biol. , vol.6 , pp. 321-324
    • Pfeiffer, S.1    Alexandre, C.2    Calleja, M.3    Vincent, J.P.4
  • 57
    • 0033520472 scopus 로고    scopus 로고
    • Structural basis for FGF receptor dimerization and activation
    • Plotnikov, A.N., Schlessinger, J., Hubbard, S.R. & Mohammadi, M. (1999) Structural basis for FGF receptor dimerization and activation. Cell, 5, 641-650.
    • (1999) Cell , vol.5 , pp. 641-650
    • Plotnikov, A.N.1    Schlessinger, J.2    Hubbard, S.R.3    Mohammadi, M.4
  • 58
    • 0029844909 scopus 로고    scopus 로고
    • Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction
    • Reichsman, F., Smith, L. & Cumberledge, S. (1996) Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction. J. Cell Biol., 3, 819-827.
    • (1996) J. Cell Biol. , vol.3 , pp. 819-827
    • Reichsman, F.1    Smith, L.2    Cumberledge, S.3
  • 59
    • 0025094664 scopus 로고
    • Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless
    • Riggleman, B., Schedl, P. & Wieschaus, E. (1990) Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless. Cell, 3, 549-560.
    • (1990) Cell , vol.3 , pp. 549-560
    • Riggleman, B.1    Schedl, P.2    Wieschaus, E.3
  • 61
    • 0035680634 scopus 로고    scopus 로고
    • Generating patterns from fields of cells. Examples from Drosophila segmentation
    • Sanson, B. (2001) Generating patterns from fields of cells. Examples from Drosophila segmentation. EMBO Rep., 12, 1083-1088.
    • (2001) EMBO Rep. , vol.12 , pp. 1083-1088
    • Sanson, B.1
  • 62
    • 0034191875 scopus 로고    scopus 로고
    • Proteoglycans and pattern formation: Sugar biochemistry meets developmental genetics
    • Selleck, S.B. (2000) Proteoglycans and pattern formation: Sugar biochemistry meets developmental genetics. Trends Genet., 5, 206-212.
    • (2000) Trends Genet. , vol.5 , pp. 206-212
    • Selleck, S.B.1
  • 63
    • 0035917498 scopus 로고    scopus 로고
    • Apical localization of wingless transcripts is required for wingless signaling
    • Simmonds, A.J., dos Santos, G., Livne-Bar, I. & Krause, H.M. (2001) Apical localization of wingless transcripts is required for wingless signaling. Cell, 2, 197-207.
    • (2001) Cell , vol.2 , pp. 197-207
    • Simmonds, A.J.1    dos Santos, G.2    Livne-Bar, I.3    Krause, H.M.4
  • 64
    • 0034704824 scopus 로고    scopus 로고
    • Wingless gradient formation in the Drosophila wing
    • Strigini, M. & Cohen, S.M. (2000) Wingless gradient formation in the Drosophila wing. Curr. Biol., 6, 293-300.
    • (2000) Curr. Biol. , vol.6 , pp. 293-300
    • Strigini, M.1    Cohen, S.M.2
  • 65
    • 0028178786 scopus 로고
    • Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs
    • Tabata, T. & Kornberg, T.B. (1994) Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell, 1, 89-102.
    • (1994) Cell , vol.1 , pp. 89-102
    • Tabata, T.1    Kornberg, T.B.2
  • 67
    • 0037066744 scopus 로고    scopus 로고
    • Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum
    • Tanaka, K., Kitagawa, Y. & Kadowaki, T. (2002) Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum. J. Biol. Chem., 15, 12816-12823.
    • (2002) J. Biol. Chem. , vol.15 , pp. 12816-12823
    • Tanaka, K.1    Kitagawa, Y.2    Kadowaki, T.3
  • 68
    • 0343967010 scopus 로고    scopus 로고
    • Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs
    • Tanimoto, H., Itoh, S., ten Dijke, P. & Tabata, T. (2000) Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs. Mol. Cell, 1, 59-71.
    • (2000) Mol. Cell , vol.1 , pp. 59-71
    • Tanimoto, H.1    Itoh, S.2    ten Dijke, P.3    Tabata, T.4
  • 69
    • 0033636094 scopus 로고    scopus 로고
    • Dpp gradient formation in the Drosophila wing imaginal disc
    • Teleman, A.A. & Cohen, S.M. (2000) Dpp gradient formation in the Drosophila wing imaginal disc. Cell, 6, 971-980.
    • (2000) Cell , vol.6 , pp. 971-980
    • Teleman, A.A.1    Cohen, S.M.2
  • 70
    • 0037343952 scopus 로고    scopus 로고
    • Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity
    • Tolwinski, N.S., Wehrli, M., Rives, A., Erdeniz, N., DiNardo, S. & Wieschaus, E. (2003) Wg/Wnt signal can be transmitted through arrow/ LRP5,6 and Axin independently of Zw3/Gsk3beta activity. Dev. Cell, 3, 407-418.
    • (2003) Dev. Cell , vol.3 , pp. 407-418
    • Tolwinski, N.S.1    Wehrli, M.2    Rives, A.3    Erdeniz, N.4    DiNardo, S.5    Wieschaus, E.6
  • 73
    • 0027368963 scopus 로고
    • Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein
    • van den Heuvel, M., Harryman-Samos, C., Klingensmith, J., Perrimon, N. & Nusse, R. (1993) Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. Embo. J., 13, 5293-5302.
    • (1993) Embo. J. , vol.13 , pp. 5293-5302
    • van den Heuvel, M.1    Harryman-Samos, C.2    Klingensmith, J.3    Perrimon, N.4    Nusse, R.5
  • 74
    • 0024453493 scopus 로고
    • Distribution of the wingless gene product in Drosophila embryos: A protein involved in cell-cell communication
    • van den Heuvel, M., Nusse, R., Johnston, P. & Lawrence, P.A. (1989) Distribution of the wingless gene product in Drosophila embryos: A protein involved in cell-cell communication. Cell, 4, 739-749.
    • (1989) Cell , vol.4 , pp. 739-749
    • van den Heuvel, M.1    Nusse, R.2    Johnston, P.3    Lawrence, P.A.4
  • 76
    • 0033565533 scopus 로고    scopus 로고
    • Wnt-induced dephosphorylation of axin releases betacatenin from the axin complex
    • Willert, K., Shibamoto, S. & Nusse, R. (1999) Wnt-induced dephosphorylation of axin releases betacatenin from the axin complex. Genes Dev., 14, 1768-1773.
    • (1999) Genes Dev. , vol.14 , pp. 1768-1773
    • Willert, K.1    Shibamoto, S.2    Nusse, R.3
  • 77
    • 0024786826 scopus 로고
    • Positional information revisited
    • Wolpert, L. (1989) Positional information revisited. Development, 3-12.
    • (1989) Development , pp. 3-12
    • Wolpert, L.1
  • 78
    • 0036830126 scopus 로고    scopus 로고
    • Ligand receptor interactions in the Wnt signaling pathway in Drosophila
    • Wu, C.H. & Nusse, R. (2002) Ligand receptor interactions in the Wnt signaling pathway in Drosophila. J. Biol. Chem., 44, 41762-41769.
    • (2002) J. Biol. Chem. , vol.44 , pp. 41762-41769
    • Wu, C.H.1    Nusse, R.2
  • 79
    • 0033574527 scopus 로고    scopus 로고
    • Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability
    • Yamaoto, H., Kishida, S., Kishida, M., Ikeda, S., Takada, S. & Kikuchi, A. (1999) Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability. J. Biol. Chem., 16, 10681-10684.
    • (1999) J. Biol. Chem. , vol.16 , pp. 10681-10684
    • Yamaoto, H.1    Kishida, S.2    Kishida, M.3    Ikeda, S.4    Takada, S.5    Kikuchi, A.6
  • 80
    • 0030606264 scopus 로고    scopus 로고
    • Direct and long-range action of a wingless morphogen gradient
    • Zecca, M., Basler, K. & Struhl, G. (1996) Direct and long-range action of a wingless morphogen gradient. Cell, 5, 833-844.
    • (1996) Cell , vol.5 , pp. 833-844
    • Zecca, M.1    Basler, K.2    Struhl, G.3
  • 81
    • 4043154959 scopus 로고    scopus 로고
    • Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine
    • Zhai, L., Chaturvedi, D. & Cumberledge, S. (2004) Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine. J. Biol. Chem., 32, 33220-33227.
    • (2004) J. Biol. Chem. , vol.32 , pp. 33220-33227
    • Zhai, L.1    Chaturvedi, D.2    Cumberledge, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.